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<div class="h1">Accessing CCRIS Content from PubChem</div>
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<p>CCRIS content are migrated to PubChem. Follow the steps below to find the CCRIS content in PubChem.</p>
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<ol>
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<li>Start CCRIS search in PubChem
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<ol style="list-style-type: lower-alpha;">
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<li>Clicking on the <a href="https://www.ncbi.nlm.nih.gov/pcsubstance?term=%22Chemical%20Carcinogenesis%20Research%20Information%20System%20(CCRIS)%22%5BSourceName%5D%20AND%20hasnohold%5Bfilt%5D">CCRIS in PubChem</a> link on the <a href="https://www.nlm.nih.gov/toxnet/index.html">TOXNET transition page</a>, OR</li>
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<li>Clicking on the <a href="https://www.ncbi.nlm.nih.gov/pcsubstance?term=%22Chemical%20Carcinogenesis%20Research%20Information%20System%20(CCRIS)%22%5BSourceName%5D%20AND%20hasnohold%5Bfilt%5D">9,562 Live Substances</a> link on the <a href="https://pubchem.ncbi.nlm.nih.gov/source/22070"> PubChem data source page for CCRIS</a>, or simply search “CCRIS" at the <a href="https://pubchem.ncbi.nlm.nih.gov/">PubChem homepage</a>, to see the CCRIS data source page in PubChem.<br /><br /></li>
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</ol>
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</li>
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<li>The link will take you to PubChem Substance search results page. Enter a chemical search term followed by “AND” <em>without the quotes </em>before the “Carcinogenesis Research Information System
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<p><img class="img-fluid" src="images/Accessing_CCRIS_Content_from_PubChem/Image_001.png" alt="Screen capture of PubChem Substance showing a search term of " /></p>
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</li>
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<li>Clicking on the chemical in the search results will take you to the PubChem Substance record page from the source CCRIS.
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<p><img class="img-fluid" src="images/Accessing_CCRIS_Content_from_PubChem/Image_002.png" alt="Screen capture of PubChem Substance showing CCRIS Acrylamide record." /></p>
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</li>
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<li>In the “Contents” table on the right, click on <strong>Depositor Comments</strong>. CCRIS meta data is shown in this section, including the Data type.
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<p><img class="img-fluid" src="images/Accessing_CCRIS_Content_from_PubChem/Image_003.png" alt="Screen capture of PubChem Substance showing Depositor Comments section of the CCRIS Acrylamide record" /></p>
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</li>
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<li>In the “Contents” table, click on “Biological Test Results”. In the <strong>BioAssay Results </strong>table, click on any of the links in the <strong>Activity </strong>column.
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<p><img class="img-fluid" src="images/Accessing_CCRIS_Content_from_PubChem/Image_004.png" alt="Screen capture of PubChem Substance showing Bioassay Results section of the CCRIS Acrylamide record." /></p>
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</li>
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<li>Now you are at PubChem BioAssay page for this chemical and this type of bioassay.
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<p><img class="img-fluid" src="images/Accessing_CCRIS_Content_from_PubChem/Image_005.png" alt="Screen capture of PubChem BioAssay showing the CCRIS Acrylamide and CCRIS carcinogenicity studies record." /></p>
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</li>
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<li>Scroll down to the <strong>Test Results </strong>section. Here you will see all the results of this type of bioassay for this chemical. Screen capture of PubChem BioAssay showing the CCRIS Acrylamide and CCRIS carcinogenicity studies record.
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<p><img class="img-fluid" src="images/Accessing_CCRIS_Content_from_PubChem/Image_006.png" alt="Screen capture of PubChem BioAssay showing the CCRIS Acrylamide and Test Results of the CCRIS carcinogenicity studies." /></p>
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</li>
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<li>Scroll down to the next section <strong>Related Bioactivities</strong>. Other types of bioassays in CCRIS are shown here.
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<p><img class="img-fluid" src="images/Accessing_CCRIS_Content_from_PubChem/Image_007.png" alt="Screen capture of PubChem BioAssay showing the CCRIS Acrylamide and Other Bioassay section of the CCRIS carcinogenicity studies." /></p>
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</li>
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<li>Clicking on any of the links in Activity column will take you to the BioAssay page for this type of bioassay. Scroll down to the Test Results section to view the test results data.
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<p><img class="img-fluid" src="images/Accessing_CCRIS_Content_from_PubChem/Image_008.png" alt="Screen capture of PubChem BioAssay showing the CCRIS Acrylamide and Test Results of the CCRIS mutagenicity studies." /></p>
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</li>
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</ol>
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<p class=”margin-top-5”><small>Last Reviewed: September 19, 2019</small></p>
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