1788 lines
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1788 lines
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<p>Use these free education and outreach materials in your community and on social media to spread the word about mental health and related topics.</p>
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<p>NIMH supports research at universities, medical centers, and other institutions via grants, contracts, and cooperative agreements. Learn more about NIMH research areas, policies, resources, and initiatives.</p>
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<p>The Division of Intramural Research Programs (IRP) is the internal research division of the NIMH. Over 40 research groups conduct basic neuroscience research and clinical investigations of mental illnesses, brain function, and behavior at the NIH campus in Bethesda, Maryland. Learn more about research conducted at NIMH.</p>
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<p>Learn about NIMH priority areas for research and funding that have the potential to improve mental health care over the short, medium, and long term.</p>
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<p><a href="/funding/opportunities-announcements/clinical-trials-foas">Support for Clinical Trials at NIMH</a></p>
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<h2 class="index_news_year_header">Updates by Year</h2>
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<li class="index_year_list_item link-container"><a href="/news/science-updates/2025" class="single-link">2025</a></li>
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<h2 class="index_news_topic_header">Updates by Topic</h2>
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<h3 class="index_news_topic_subheader" data-am-aggnav="level1"><span>Health Topics</span></h3>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/anxiety-disorders">Anxiety Disorders</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/autism-spectrum-disorder-asd">Autism Spectrum Disorder (ASD)</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/bipolar-disorder">Bipolar Disorder</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/covid-19">COVID-19</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/depression">Depression</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/disruptive-mood-dysregulation-disorder-dmdd">Disruptive Mood Dysregulation Disorder</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/hiv-aids">HIV/AIDS</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/obsessive-compulsive-disorder-ocd">Obsessive-Compulsive Disorder (OCD)</a></li>
|
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/post-traumatic-stress-disorder-ptsd">Post-Traumatic Stress Disorder (PTSD)</a></li>
|
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/psychosis">Psychosis</a></li>
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<h3 class="index_news_topic_subheader" data-am-aggnav="level1"><span>Populations</span></h3>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/children-and-adolescents">Children and Adolescents</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/global-mental-health">Global Mental Health</a></li>
|
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/mens-mental-health">Men’s Mental Health</a></li>
|
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/military-servicemembers">Military Service Members</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/older-adults">Older Adults</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/womens-mental-health">Women’s Mental Health</a></li>
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<h3 class="index_news_topic_subheader" data-am-aggnav="level1"><span>Research</span></h3>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/the-brain-initiative">BRAIN Initiative</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/clinical-research-and-trials">Clinical Research and Trials</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/health-disparities">Health Disparities</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/mental-health-services-research">Mental Health Services Research</a></li>
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/research-funding">Research Funding</a></li>
|
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/treatments">Treatments</a></li>
|
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|
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<ul class="index_news_topic_list">
|
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/nimhs-75th-anniversary">75th Anniversary</a></li>
|
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<li class="index_topic_list_item link-container"><a class="index_topic_list_text" href="/news/science-updates/institute-announcements">Institute Announcements</a></li>
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<div class="titleblock">
|
||
<h1 class="titleblock__title" id="title">Science Updates About Genetics</h1>
|
||
</div>
|
||
<dl class="aggregator_news">
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2025/study-illuminates-the-genetic-architecture-of-bipolar-disorder"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/thumbnails/genomics-bipolar-thumbnail.jpg"
|
||
alt="DNA strand. "
|
||
data-mid="23497"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2025/study-illuminates-the-genetic-architecture-of-bipolar-disorder">Study Illuminates the Genetic Architecture of Bipolar Disorder</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2025-03-04">March 4, 2025
|
||
• Research Highlight</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Largest-ever genome-wide study of a diverse group of people with bipolar disorder sheds new light on the genetic architecture underlying the disorder.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2024/new-gene-delivery-method-paves-the-way-for-advanced-brain-therapies"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/thumbnails/gene-delivery-thumbnail.jpg"
|
||
alt="Illustration of a brain intertwined with a DNA double helix, depicted as a network of glowing, purple connections on a dark background."
|
||
data-mid="23209"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2024/new-gene-delivery-method-paves-the-way-for-advanced-brain-therapies">New Gene Delivery Method Paves the Way for Advanced Brain Therapies</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2024-08-15">August 15, 2024
|
||
• Research Highlight</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>A new study, funded in part by the National Institute of Mental Health, describes a promising new gene delivery vehicle that could advance treatment for brain disorders. </p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2024/scientists-map-networks-regulating-gene-function-in-the-human-brain"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news/abstract-dna-molecule-helix-and-brain-120x120.jpg"
|
||
alt="Illustration of a DNA helix over top of a human brain"
|
||
data-mid="23094"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2024/scientists-map-networks-regulating-gene-function-in-the-human-brain">Scientists Map Networks Regulating Gene Function in the Human Brain</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2024-05-23">May 23, 2024
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>An NIMH-funded research consortium has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2024/gene-based-therapy-restores-cellular-development-and-function-in-brain-cells-from-people-with-timothy-syndrome"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/thumb-fig-5c-staining1.jpg"
|
||
alt="Image showing transplanted human cortical organoids made from cells taken from individuals with Timothy syndrome with immunostaining. Chen et al., Nature. "
|
||
data-mid="23048"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2024/gene-based-therapy-restores-cellular-development-and-function-in-brain-cells-from-people-with-timothy-syndrome">Gene-Based Therapy Restores Cellular Development and Function in Brain Cells From People With Timothy Syndrome</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2024-04-24">April 24, 2024
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>In a proof-of-concept study, researchers demonstrated the effectiveness of a potential new therapy for Timothy syndrome, an often life-threatening and rare genetic disorder that affects a wide range of bodily systems, leading to severe cardiac, neurological, and psychiatric symptoms as well as physical differences such as webbed fingers and toes. </p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2024/decades-of-dedication-and-collaboration-unraveling-the-hiv-mystery"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/news/science-news/2024/swarm_of_human_immunodeficiency_virus_thumb.jpg"
|
||
alt="Swarm of human immunodeficiency virus. Credit: istock/fpm."
|
||
data-mid="22845"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2024/decades-of-dedication-and-collaboration-unraveling-the-hiv-mystery">Decades of Dedication and Collaboration: Unraveling the HIV Mystery</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2024-01-29">January 29, 2024
|
||
• Feature Story</time> • <span class='anniversary-tag'>75th Anniversary</span>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>In celebration of NIMHs 75th anniversary, we reflect on decades of work by the institute to understand and eradicate HIV.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2024/researchers-expand-understanding-of-genetic-mechanisms-underlying-fragile-x-syndrome"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/thumbnails/Spatially%20coordinated%20heterochromatinization_Thumbnail_1.jpg"
|
||
alt="Illustration of an X chromosome cut open to expose a piece of the DNA strand."
|
||
data-mid="22755"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2024/researchers-expand-understanding-of-genetic-mechanisms-underlying-fragile-x-syndrome">Researchers Expand Understanding of Genetic Mechanisms Underlying Fragile X Syndrome</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2024-01-18">January 18, 2024
|
||
• Research Highlight</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>An NIMH-supported study of the 3D genome revealed widespread silencing of genes with important roles in brain function in fragile X syndrome and related disorders.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2023/scientists-unveil-complete-cell-map-of-a-whole-mammalian-brain"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/news/science-news/2023/BICCN%20Thumbnail.jpg"
|
||
alt="Spatial distribution of diverse cell types in the mouse brain. Here, MERFISH was used to measure 500 genes in the mouse brain to reveal the complex distribution of cell types throughout the brain. Courtesy of Yao/van Velthoven/Zeng, Allen Institute."
|
||
data-mid="22739"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2023/scientists-unveil-complete-cell-map-of-a-whole-mammalian-brain">Scientists Unveil Complete Cell Map of a Whole Mammalian Brain</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2023-12-13">December 13, 2023
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>For the first time ever, an international team of researchers has created a complete cell atlas of a whole mammalian brain.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2023/scientists-unveil-detailed-cell-maps-of-the-human-brain-and-the-nonhuman-primate-brain"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/news/science-news/2023/Thumbnail_Abstract%20image%20of%20brain%20with%20lines%20and%20dots_0.jpg"
|
||
alt="Illustration of abstract brain on blue background."
|
||
data-mid="22601"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2023/scientists-unveil-detailed-cell-maps-of-the-human-brain-and-the-nonhuman-primate-brain">Scientists Unveil Detailed Cell Maps of the Human Brain and the Nonhuman Primate Brain </a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2023-10-12">October 12, 2023
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>A group of international scientists have mapped the genetic, cellular, and structural makeup of the human brain and the nonhuman primate brain, allowing for a deeper knowledge of the cellular basis of brain function and dysfunction, helping pave the way for a new generation of precision therapeutics for people with mental disorders and other disorders of the brain.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2023/researchers-solve-the-puzzle-of-a-brain-receptors-activation"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/thumbnails/Glycine-docking-GPR158_Thumbnail%20image_0.jpg"
|
||
alt="Model showing glycine (teal) docking on the receptor GPR158. The dotted lines show contacts glycine molecule forms with GPR158. Courtesy of the Martemyanov lab, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology."
|
||
data-mid="22322"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2023/researchers-solve-the-puzzle-of-a-brain-receptors-activation">Researchers Solve the Puzzle of a Brain Receptor’s Activation</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2023-06-20">June 20, 2023
|
||
• Research Highlight</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Researchers in a NIMH-supported study identified a new receptor for glycine that helps enhance communication between nerve cells in the brain and offers a potential new target for treating mental disorders.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2023/researchers-unlock-genetic-mutations-contributing-to-disorders-in-the-brain"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/multicolor-brain-tn_0.jpg"
|
||
alt="Multi-colored brain in space with a dotted background. Courtesy of the Gleeson Lab for Pediatric Brain Disease, University of California San Diego and Rady Children's Institute for Genomic Medicine."
|
||
data-mid="22154"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2023/researchers-unlock-genetic-mutations-contributing-to-disorders-in-the-brain">Researchers Unlock Genetic Mutations Contributing to Disorders in the Brain </a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2023-04-10">April 10, 2023
|
||
• Research Highlight</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Researchers identified novel genes with mosaic mutations contributing to treatment-resistant pediatric epilepsy and pointing to specific disrupted pathways in cortical development.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2023/new-nih-study-reveals-shared-genetic-markers-underlying-substance-use-disorders"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/thumbnails/NIDA%20genetics%20release%20-%20stadium%20crowd%20-%20thumbnail.jpg"
|
||
alt="Overhead shot of crowd watching a sports event."
|
||
data-mid="22096"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2023/new-nih-study-reveals-shared-genetic-markers-underlying-substance-use-disorders">New NIH Study Reveals Shared Genetic Markers Underlying Substance Use Disorders</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2023-03-22">March 22, 2023
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Analyzing genomic data from more than 1 million people, researchers have identified genes that are commonly inherited across substance use disorders, regardless of the substance being used.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2022/researchers-map-the-genetic-landscape-of-schizophrenia-in-the-brain"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/Thumbnail-Image_Researchers-Map-the-Genetic-Landscape-in-Schizophrenia-thumbnail.png"
|
||
alt="DNA strand beside a side profile of a head with the brain illuminated, on an abstract digital background "
|
||
data-mid="21856"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2022/researchers-map-the-genetic-landscape-of-schizophrenia-in-the-brain">Researchers Map the Genetic Landscape of Schizophrenia in the Brain</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2022-11-29">November 29, 2022
|
||
• Research Highlight</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>In a comprehensive postmortem genetic analysis of the caudate nucleus in the brain, NIMH-supported researchers identified many genes associated with schizophrenia risk, including a gene that regulates the flow of the chemical messenger dopamine.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2022/nih-brain-initiative-launches-projects-to-develop-cell-atlases-and-molecular-tools-for-cell-access"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/neuronal-connections.png"
|
||
alt="Illustration of neuronal connections."
|
||
data-mid="21029"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2022/nih-brain-initiative-launches-projects-to-develop-cell-atlases-and-molecular-tools-for-cell-access">NIH BRAIN Initiative Launches Projects to Develop Cell Atlases and Molecular Tools for Cell Access</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2022-09-22">September 22, 2022
|
||
• Institute Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>The National Institutes of Health has launched two transformative projects supported by the Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative: The BRAIN Initiative® Cell Atlas Network and the Armamentarium for Precision Brain Cell Access.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2022/autism-and-congenital-heart-disease-share-underlying-molecular-network"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/research-highlights/featured-images/blue_molecule_things_featured.jpg"
|
||
alt="3D rendering of a molecule"
|
||
data-mid="21296"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2022/autism-and-congenital-heart-disease-share-underlying-molecular-network">Autism and Congenital Heart Disease Share Underlying Molecular Network</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2022-03-17">March 17, 2022
|
||
• Research Highlight</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>A recent study of gene networks may hold some promising clues about shared mechanisms underlying autism spectrum disorder and congenital heart disease, two physiologically distinct disorders that often co-occur.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2021/nih-fda-and-15-private-organizations-join-forces-to-increase-effective-gene-therapies-for-rare-diseases"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/bespoke_gene_featured.jpg"
|
||
alt="Word cloud with text arranged on background. "
|
||
data-mid="21053"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2021/nih-fda-and-15-private-organizations-join-forces-to-increase-effective-gene-therapies-for-rare-diseases">NIH, FDA and 15 Private Organizations Join Forces to Increase Effective Gene Therapies for Rare Diseases</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2021-10-29">October 29, 2021
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>The newly launched Bespoke Gene Therapy Consortium (BGTC), part of the NIH Accelerating Medicines Partnership (AMP) program, aims to optimize and streamline the gene therapy development process to help fill the unmet medical needs of people with rare diseases.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2021/nih-brain-initiative-unveils-detailed-atlas-of-the-mammalian-primary-motor-cortex"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/neuronal-connections.png"
|
||
alt="Illustration of neuronal connections."
|
||
data-mid="21029"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2021/nih-brain-initiative-unveils-detailed-atlas-of-the-mammalian-primary-motor-cortex">NIH BRAIN Initiative Unveils Detailed Atlas of the Mammalian Primary Motor Cortex</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2021-10-06">October 6, 2021
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>The NIH Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative Cell Census Network (BICCN) has unveiled an atlas of cell types and an anatomical neuronal wiring diagram for the mammalian primary motor cortex, derived from detailed studies of mice, monkeys, and humans.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2021/genomic-data-from-more-than-41000-people-shed-new-light-on-bipolar-disorder"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/gwas_bipolar_disorder_120x120.png"
|
||
alt="Image of brain and DNA strands"
|
||
data-mid="21023"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2021/genomic-data-from-more-than-41000-people-shed-new-light-on-bipolar-disorder">Genomic Data From More Than 41,000 People Shed New Light on Bipolar Disorder</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2021-09-29">September 29, 2021
|
||
• Research Highlight</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>In the largest genome-wide association study of bipolar disorder to date, researchers found about twice as many genetic locations associated with bipolar disorder as reported in previous studies. These and other findings help improve our understanding of the biological origins of bipolar disorder.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2021/researchers-use-exosome-based-strategy-to-block-hiv-in-mice"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/exosomes_featured.png"
|
||
alt=" A high-powered black and white microscope image showing exosomes, nanosized parts of cells. (Credit: Surya Shrivastava / City of Hope"
|
||
data-mid="21005"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2021/researchers-use-exosome-based-strategy-to-block-hiv-in-mice">Researchers Use Exosome-Based Strategy to Block HIV in Mice</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2021-09-21">September 21, 2021
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>In this NIMH-funded study, researchers used exosomes to deliver novel protein into the cells of mice infected with HIV. The protein attached to HIV’s genetic material and prevented it from replicating, resulting in reduced levels of HIV in the bone marrow, spleen, and brain.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2021/gene-readouts-contribute-to-distinctness-of-mental-disorders"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/dna_structure.jpg"
|
||
alt="Illustration of DNA double helix"
|
||
data-mid="17606"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2021/gene-readouts-contribute-to-distinctness-of-mental-disorders">Gene Readouts Contribute To Distinctness of Mental Disorders</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2021-02-09">February 9, 2021
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>A new study conducted by researchers at NIMH suggests that differences in the expression of gene transcripts – readouts copied from DNA that help maintain and build our cells – may hold the key to understanding how mental disorders with shared genetic risk factors result in different patterns of onset, symptoms, course of illness, and treatment responses.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2020/nih-funded-study-sheds-light-on-abnormal-neural-function-in-rare-genetic-disorder"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/brain_blue_neurons_featured.jpg"
|
||
alt="Image of brain neurons"
|
||
data-mid="17506"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2020/nih-funded-study-sheds-light-on-abnormal-neural-function-in-rare-genetic-disorder">NIH-funded Study Sheds Light on Abnormal Neural Function in Rare Genetic Disorder</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2020-09-28">September 28, 2020
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>A genetic study has identified neuronal abnormalities in the electrical activity of cortical cells derived from people with a rare genetic disorder called 22q11.2 deletion syndrome.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2020/genetic-variations-highlight-the-importance-of-metabolic-processes-in-anorexia"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/research-highlights/featured-images/molecular_structure_illustration.jpg"
|
||
alt="artistic illustration of a molecular structure"
|
||
data-mid="16045"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2020/genetic-variations-highlight-the-importance-of-metabolic-processes-in-anorexia">Genetic Variations Highlight the Importance of Metabolic Processes in Anorexia</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2020-07-22">July 22, 2020
|
||
• Research Highlight</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>The need to identify effective targets for intervention in anorexia nervosa is pressing, as patient outcomes are often poor. An NIMH-funded genome-wide association study suggests that metabolic processes may play an important role in the disorder, offering a promising new avenue for investigation.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2020/study-shows-highly-reproducible-sex-differences-in-aspects-of-human-brain-anatomy"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/human_brain_blueprint_featured.jpg"
|
||
alt="blueprint style line drawing of human brain"
|
||
data-mid="17694"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2020/study-shows-highly-reproducible-sex-differences-in-aspects-of-human-brain-anatomy">Study Shows Highly Reproducible Sex Differences in Aspects of Human Brain Anatomy</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2020-07-20">July 20, 2020
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>A scientific analysis of more than 2,000 brain scans found evidence for highly reproducible sex differences in the volume of certain regions in the human brain.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2020/large-scale-genetics-study-sheds-light-on-developmental-origins-of-autism"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/research-highlights/featured-images/double_helix_dna_strands.jpg"
|
||
alt="This image shows double-helix DNA strands."
|
||
data-mid="16042"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2020/large-scale-genetics-study-sheds-light-on-developmental-origins-of-autism">Large-Scale Genetics Study Sheds Light on Developmental Origins of Autism</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2020-03-06">March 6, 2020
|
||
• Research Highlight</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Researchers were able to identify different types of rare genetic variations associated with autism spectrum disorder by analyzing data shared via the NIMH-funded Autism Sequencing Consortium.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2019/schizophrenia-risk-gene-linked-to-cognitive-deficits-in-mice"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/neuronal_spines_featured.png"
|
||
alt="Neuronal spines"
|
||
data-mid="17752"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2019/schizophrenia-risk-gene-linked-to-cognitive-deficits-in-mice">Schizophrenia Risk Gene Linked to Cognitive Deficits in Mice</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2019-10-24">October 24, 2019
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Mice with an impaired version of one the few genes definitively linked to schizophrenia showed abnormalities in working memory, mimicking those commonly seen in schizophrenia patients.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2019/gene-regulators-work-together-for-oversized-impact-on-schizophrenia-risk"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/induced_human_neuron_featured.jpg"
|
||
alt="microscopic image of an induced human neuron"
|
||
data-mid="17677"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2019/gene-regulators-work-together-for-oversized-impact-on-schizophrenia-risk">Gene Regulators Work Together for Oversized Impact on Schizophrenia Risk</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2019-09-23">September 23, 2019
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Gene expression regulators work together to raise an individual’s risk of developing schizophrenia. Schizophrenia-like gene expression changes modeled in human neurons matched changes found in patients’ brains.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2018/2000-human-brains-yield-clues-to-how-genes-raise-risk-for-mental-illnesses"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/brain_molecular_structure_featured.jpg"
|
||
alt="brain scan showing molecular structure"
|
||
data-mid="17564"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2018/2000-human-brains-yield-clues-to-how-genes-raise-risk-for-mental-illnesses">2,000 Human Brains Yield Clues to How Genes Raise Risk for Mental Illnesses</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2018-12-20">December 20, 2018
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>PsychENCODE researchers are discovering the biological mechanisms by which mental illness risk genes work in the human brain.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2018/nih-brain-initiative-debuts-cell-census-of-mouse-motor-cortex-for-starters"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/mouse_optic_region_cells_featured.jpg"
|
||
alt="Mouse preoptic region cell clusters"
|
||
data-mid="17753"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2018/nih-brain-initiative-debuts-cell-census-of-mouse-motor-cortex-for-starters">NIH BRAIN Initiative Debuts Cell Census of Mouse Motor Cortex – for Starters</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2018-11-01">November 1, 2018
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>NIH BRAIN Initiative Cell Census Network (BICCN) has debuted its first data release, which focuses on motor cortex. In a related development, researchers have discovered cellular secrets of key social behaviors – mating, parenting, and aggression – in mouse hypothalamus.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2018/inherited-variations-in-noncoding-sections-of-dna-associated-with-autism"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/dna_helix_featured.jpg"
|
||
alt="Illustration of a DNA double helix"
|
||
data-mid="17604"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2018/inherited-variations-in-noncoding-sections-of-dna-associated-with-autism">Inherited Variations in Noncoding Sections of DNA Associated with Autism</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2018-05-30">May 30, 2018
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>A new study has identified an association between paternally-inherited rare structural variants in noncoding segments of genes and the development of autism spectrum disorder (ASD). The study adds to a growing body of research describing genetic contributors to ASD.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2018/suspect-molecules-overlap-in-autism-schizophrenia-bipolar-disorder"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/transcriptome-correlation-featured.jpg"
|
||
alt="Chart shows correlations of gene expression between mental disorders."
|
||
data-mid="17845"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2018/suspect-molecules-overlap-in-autism-schizophrenia-bipolar-disorder">Suspect Molecules Overlap in Autism, Schizophrenia, Bipolar Disorder</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2018-03-01">March 1, 2018
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Depression, schizophrenia and autism spectrum disorder share some of the same patterns of suspect gene expression – molecular signatures.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2017/nih-completes-atlas-of-human-dna-differences-that-influence-gene-expression"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/gtex_featured.jpg"
|
||
alt="gene illustration"
|
||
data-mid="17650"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2017/nih-completes-atlas-of-human-dna-differences-that-influence-gene-expression">NIH Completes Atlas of Human DNA Differences that Influence Gene Expression</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2017-10-12">October 12, 2017
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>NIH researchers have completed an atlas documenting how DNA influence human gene expression.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2017/breakthrough-method-yields-trove-of-neuron-subtypes-gene-regulators"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/neuron_subtype_featured.jpg"
|
||
alt="Epigenomic signatures of neuron subtypes"
|
||
data-mid="17770"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2017/breakthrough-method-yields-trove-of-neuron-subtypes-gene-regulators">Breakthrough Method Yields Trove of Neuron Subtypes, Gene Regulators</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2017-08-10">August 10, 2017
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Scientists have discovered a trove of neuronal subtypes by identifying their unique epigenomic signatures.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2017/our-brains-harbor-residual-echo-of-neanderthal-genes"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/neanderthal_brain_vision_featured.jpg"
|
||
alt="Neanderthal gene-influenced brain visual system areas"
|
||
data-mid="17737"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2017/our-brains-harbor-residual-echo-of-neanderthal-genes">Our Brains Harbor “Residual Echo” of Neanderthal Genes</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2017-07-24">July 24, 2017
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Researchers have produced the first direct evidence that parts of our brains implicated in mental disorders may be shaped by a “residual echo” from our ancient past. The more a person’s genome carries genetic vestiges of Neanderthals, the more certain parts of his or her brain and skull resemble those of humans’ evolutionary cousins that went extinct 40,000 years ago.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2017/nimh-grantee-wins-one-of-sciences-most-coveted-prizes"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/clarity_featured.jpg"
|
||
alt="3-D analysis of intact mouse hippocampus"
|
||
data-mid="17572"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2017/nimh-grantee-wins-one-of-sciences-most-coveted-prizes">NIMH Grantee Wins One of Science’s Most Coveted Prizes</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2017-05-31">May 31, 2017
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>NIMH grantee Karl Deisseroth, M.D., Ph.D., of Stanford University, has been awarded one of science’s most generous prizes. A German foundation presented the inventor of technologies that are transforming neuroscience with its 4 million euros Fresenius Prize.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2017/estrogen-alters-memory-circuit-function-in-women-with-gene-variant"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/pet_hippocampus_activation_featured.jpg"
|
||
alt="hippocampus PET scan"
|
||
data-mid="17788"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2017/estrogen-alters-memory-circuit-function-in-women-with-gene-variant">Estrogen Alters Memory Circuit Function in Women with Gene Variant</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2017-04-19">April 19, 2017
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Brain scans reveal that fluctuations in estrogen can trigger atypical functioning in a key brain memory circuit in women with a common version of a gene. Since working memory function is often disturbed in mental disorders, such gene-hormone interactions are suspect mechanisms that may confer risk.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2017/delayed-walking-may-signal-spontaneous-gene-anomalies-in-autism"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/delayedtoddlerwalking.jpg"
|
||
alt="Toddler walking - delayed"
|
||
data-mid="17590"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2017/delayed-walking-may-signal-spontaneous-gene-anomalies-in-autism">Delayed Walking May Signal Spontaneous Gene Anomalies in Autism </a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2017-03-24">March 24, 2017
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Researchers have discovered a pattern of genetic glitches and behavioral features, such as delayed walking, in some cases of autism spectrum disorder (ASD) that could ultimately lead to identification of subgroups and improved treatment.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2017/a-third-of-suspect-mutations-in-asd-just-noise"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/asd_mutation.png"
|
||
alt="ASD gene mutation"
|
||
data-mid="17531"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2017/a-third-of-suspect-mutations-in-asd-just-noise">A Third of Suspect Mutations in ASD Just “Noise”</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2017-03-23">March 23, 2017
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Researchers have narrowed suspected genetic causes of autism and related developmental disabilities by ruling out what they call the “noise of benign variation.”</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2017/sex-hormone-sensitive-gene-complex-linked-to-premenstrual-mood-disorder"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/esc-ez_gene_featured.png"
|
||
alt="ESC/E(Z) gene complex"
|
||
data-mid="17611"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2017/sex-hormone-sensitive-gene-complex-linked-to-premenstrual-mood-disorder">Sex Hormone–Sensitive Gene Complex Linked to Premenstrual Mood Disorder</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2017-01-03">January 3, 2017
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Researchers have discovered molecular mechanisms that may underlie a woman’s susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2016/molecular-tool-parses-social-fear-circuit-intertwined-with-aggression-hub"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/cane_visualized_neurons_featured.jpg"
|
||
alt="CANE visualized neurons"
|
||
data-mid="17566"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2016/molecular-tool-parses-social-fear-circuit-intertwined-with-aggression-hub">Molecular Tool Parses Social Fear Circuit Intertwined with Aggression Hub</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2016-11-30">November 30, 2016
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>A genetic engineering tool has disentangled seemingly hopelessly intertwined brain circuits for social fear and aggression in mice. </p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2016/worldwide-study-seeks-to-unlock-the-brains-genetic-code"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/magnifying_glass_brain_featured.jpg"
|
||
alt="medical background with magnifying glass examining brain"
|
||
data-mid="17710"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2016/worldwide-study-seeks-to-unlock-the-brains-genetic-code">Worldwide Study Seeks to Unlock the Brain’s Genetic Code</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2016-11-17">November 17, 2016
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Big data pinpoints genetic variation linked to brain volume and risk for disorders.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2016/nih-nearly-doubles-investment-in-brain-initiative-research"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/brainfy16_featured.jpg"
|
||
alt="BRAIN Initiative research"
|
||
data-mid="17524"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2016/nih-nearly-doubles-investment-in-brain-initiative-research">NIH Nearly Doubles Investment in BRAIN Initiative Research</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2016-10-13">October 13, 2016
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>NIH’s third round of grants to support the goals of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative total just over $150 million.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2016/powered-up-probe-ids-schizophrenia-genes-that-stunt-brain-development"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/rna_molecule_featured.png"
|
||
alt="Cropped image of RNA molecule"
|
||
data-mid="17835"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2016/powered-up-probe-ids-schizophrenia-genes-that-stunt-brain-development">Powered-Up Probe ID’s Schizophrenia Genes That Stunt Brain Development</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2016-09-27">September 27, 2016
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Scientists have pinpointed several schizophrenia-related gene variants that alter expression of other genes in illness-implicated circuitry of the human brain.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2016/schizophrenia-autism-risk-gene-trajectories-point-to-shared-causes"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/leinprimateatlasgraph-120.png"
|
||
alt="Gene activation by cortex layer featured image"
|
||
data-mid="17681"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2016/schizophrenia-autism-risk-gene-trajectories-point-to-shared-causes">Schizophrenia, Autism Risk Gene Trajectories Point to Shared Causes</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2016-08-12">August 12, 2016
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Schizophrenia, autism risk gene trajectories point to shared causes</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2016/tapping-crowd-sourced-data-unearths-a-trove-of-depression-genes"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/chromosomes_and_double_helix-featured.jpg"
|
||
alt="chromosomes and double helix"
|
||
data-mid="17571"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2016/tapping-crowd-sourced-data-unearths-a-trove-of-depression-genes">Tapping Crowd-Sourced Data Unearths a Trove of Depression Genes</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2016-08-01">August 1, 2016
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Scientists have discovered 15 genome sites – the first ever – linked to depression in people of European ancestry. But – in a twist – the researchers didn’t have to sequence anyone’s genes! Instead, they analyzed data already shared by people who had purchased their own genetic profiles via an online service and elected to participate in its research option.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2016/genome-wide-study-yields-markers-of-lithium-response"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/high-chromosomes-featured.png"
|
||
alt="High Chromosomes"
|
||
data-mid="17674"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2016/genome-wide-study-yields-markers-of-lithium-response">Genome-Wide Study Yields Markers of Lithium Response</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2016-01-28">January 28, 2016
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Genome-Wide Study Yields Markers of Lithium Response</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2016/schizophrenias-strongest-known-genetic-risk-deconstructed"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/skyline-120x120.png"
|
||
alt="C4 tower in genomic skyline featured"
|
||
data-mid="17799"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2016/schizophrenias-strongest-known-genetic-risk-deconstructed">Schizophrenia’s Strongest Known Genetic Risk Deconstructed</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2016-01-27">January 27, 2016
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Versions of a gene linked to schizophrenia may trigger runaway pruning of the teenage brain&rsquo;s still-maturing communications infrastructure.The gene switched on more in people with the suspect versions, who faced a higher risk of developing the disorder.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2015/nih-supported-neurobiobank-joins-autism-brainnet-in-brain-donation-initiative"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/model_of_brain_side_view_featured.jpg"
|
||
alt="Side view of large model of human brain"
|
||
data-mid="17740"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2015/nih-supported-neurobiobank-joins-autism-brainnet-in-brain-donation-initiative">NIH-supported NeuroBioBank Joins Autism BrainNet in Brain Donation Initiative</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2015-11-17">November 17, 2015
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Two of the world’s largest brain tissue banks unify efforts to collect and distribute a critical number of brain donations for important autism research.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2015/a-patients-budding-cortex-in-a-dish"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/neurons_spheroids_brain_featured.png"
|
||
alt="Neurons and supporting cells in the spheroids form layers and organize themselves according to the architecture of the developing human brain and network with each other. Source: Sergiu Pasca, M.D., Stanford University"
|
||
data-mid="17741"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2015/a-patients-budding-cortex-in-a-dish">A Patient’s Budding Cortex -- in a Dish?</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2015-05-29">May 29, 2015
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Scientists have perfected mini cultured 3-D structures that grow and function much like the outer mantle – the key working tissue, or cortex – of the brain of the person from whom they were derived.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2015/gtex-findings-reveal-new-insights-into-how-dna-differences-influence-gene-activity-disease-susceptibility"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/genotype_tissue_expression_project_featured.png"
|
||
alt="Genotype-Tissue Expression Project chart shows locations for liver, heart and brain tissue within the human body"
|
||
data-mid="17637"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2015/gtex-findings-reveal-new-insights-into-how-dna-differences-influence-gene-activity-disease-susceptibility">GTEx Findings Reveal New Insights into how DNA Differences Influence Gene Activity, Disease Susceptibility</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2015-05-07">May 7, 2015
|
||
• Press Release</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Data resource begins to reveal how genetic variability influences key tissues in health and disease.</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
<div class="aggregated_container clearfix">
|
||
<div class="aggregated_desc_news_iwrap"><a href="/news/science-updates/2015/disorders-share-risk-gene-pathways-for-immune-epigenetic-regulation"><img class="aggregated_desc_iwrap_image"
|
||
src="/sites/default/files/images/news-items/featured-images/blue_dna_double_helix_featured.png"
|
||
alt="double helix"
|
||
data-mid="17560"></a>
|
||
</div>
|
||
<dt class="aggregated_news_term"><a class="aggregated_term_news_link"
|
||
href="/news/science-updates/2015/disorders-share-risk-gene-pathways-for-immune-epigenetic-regulation">Disorders Share Risk Gene Pathways for Immune, Epigenetic Regulation</a></dt>
|
||
<dd class="aggregated_news_desc">
|
||
<p class="aggregated_desc_news_stamp">
|
||
<time class="aggregated_desc_news_date"
|
||
datetime="2015-01-29">January 29, 2015
|
||
• Science Update</time>
|
||
</p>
|
||
<div class="aggregated_desc_news_summary">
|
||
<p>Risk genes for different mental disorders work through same pathways</p>
|
||
</div>
|
||
</dd>
|
||
</div>
|
||
</dl>
|
||
</article>
|
||
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|
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