845 lines
61 KiB
Text
845 lines
61 KiB
Text
<!DOCTYPE html>
|
||
<html lang="en" dir="ltr" prefix="og: https://ogp.me/ns#" data-nid="11738">
|
||
<head>
|
||
<meta charset="utf-8" />
|
||
<meta name="description" content="The largest neuroimaging study of conduct disorder to date, with funding from NIH, has revealed extensive changes in brain structure among young people with the disorder. The largest difference was a smaller area of the brain’s outer layer, known as the cerebral cortex, which is critical for many aspects of behavior, cognition and emotion." />
|
||
<link rel="canonical" href="https://www.nimh.nih.gov/news/science-updates/2024/youth-with-conduct-disorder-show-widespread-differences-in-brain-structure" />
|
||
<meta property="og:site_name" content="National Institute of Mental Health (NIMH)" />
|
||
<meta property="og:title" content="Youth With Conduct Disorder Show Widespread Differences in Brain Structure" />
|
||
<meta property="og:description" content="The largest neuroimaging study of conduct disorder to date, with funding from NIH, has revealed extensive changes in brain structure among young people with the disorder. The largest difference was a smaller area of the brain’s outer layer, known as the cerebral cortex, which is critical for many aspects of behavior, cognition and emotion." />
|
||
<meta property="og:image" content="https://www.nimh.nih.gov/sites/default/files/styles/full/public/images/news/social-media/conduct-disorder-brain-structure-social-media.jpg?itok=WmC9c1Dr" />
|
||
<meta name="twitter:card" content="summary_large_image" />
|
||
<meta name="twitter:description" content="The largest neuroimaging study of conduct disorder to date, with funding from NIH, has revealed extensive changes in brain structure among young people with the disorder. The largest difference was a smaller area of the brain’s outer layer, known as the cerebral cortex, which is critical for many aspects of behavior, cognition and emotion." />
|
||
<meta name="twitter:title" content="Youth With Conduct Disorder Show Widespread Differences in Brain Structure" />
|
||
<meta name="twitter:site" content="@nimhgov" />
|
||
<meta name="twitter:image" content="https://www.nimh.nih.gov/sites/default/files/styles/full/public/images/news/social-media/conduct-disorder-brain-structure-social-media.jpg?itok=WmC9c1Dr" />
|
||
<meta name="google-site-verification" content="lKfmfhtNgohd8-snRwpaLWOcbbkS_saLoN9IUJKBvUM" />
|
||
<meta name="Generator" content="Drupal 10 (https://www.drupal.org)" />
|
||
<meta name="MobileOptimized" content="width" />
|
||
<meta name="HandheldFriendly" content="true" />
|
||
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
|
||
<script>
|
||
var mainDomain = document.location.hostname.match(/(([^.\/]+\.[^.\/]{2,3}\.[^.\/]{2})|(([^.\/]+\.)[^.\/]{2,4}([^.\/]+\.)[^.\/]{2,4}))(\/.*)?$/)[1];
|
||
try{dataLayer.push({'baseDomain': mainDomain.toLowerCase()});}
|
||
catch(err){ dataLayer = [{'baseDomain': mainDomain.toLowerCase()}];} (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':
|
||
new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],
|
||
j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src=
|
||
'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);
|
||
})(window,document,'script','dataLayer','GTM-T58NF4');
|
||
</script>
|
||
<script>
|
||
window._monsido = window._monsido || {
|
||
token: "VsAIOc905Tjeazm18evt9w",
|
||
statistics: {
|
||
enabled: true,
|
||
cookieLessTracking: true,
|
||
documentTracking: {
|
||
enabled: true,
|
||
documentCls: "",
|
||
documentIgnoreCls: "",
|
||
documentExt: ["doc","docx","pdf","ppt","pptx","rtf","txt","xls","xlsx"],
|
||
},
|
||
},
|
||
heatmap: {
|
||
enabled: true,
|
||
},
|
||
};
|
||
</script>
|
||
<script type="text/javascript" src="https://app-script.monsido.com/v2/monsido-script.js" async></script>
|
||
<link rel="icon" href="/themes/nimhtheme/favicon.ico" type="image/vnd.microsoft.icon" />
|
||
|
||
<title>Youth With Conduct Disorder Show Widespread Differences in Brain Structure - National Institute of Mental Health (NIMH)</title>
|
||
<link rel="stylesheet" media="all" href="/sites/default/files/css/css_ZTsUHDjQheI_A-r3j4HasLaMAxDXgu8kk05RpTWGtEs.css?delta=0&language=en&theme=nimhtheme&include=eJxNybsNwCAMBcCFIMxkwgMs-RPFbtg-ba49xWBqkyXxXjc9yW7FWHduKNoS7yQ18gjb-of7EtTpllHiREJbp8AH6ZgfHQ" />
|
||
<link rel="stylesheet" media="all" href="/sites/default/files/css/css_hCFOd9odoQi9Sb_-X1tdJUsdnGzf9PI7mC1Uc81hfRY.css?delta=1&language=en&theme=nimhtheme&include=eJxNybsNwCAMBcCFIMxkwgMs-RPFbtg-ba49xWBqkyXxXjc9yW7FWHduKNoS7yQ18gjb-of7EtTpllHiREJbp8AH6ZgfHQ" />
|
||
<link rel="stylesheet" media="all" href="//fonts.googleapis.com/css?family=Open+Sans:400,700|Roboto:400,500|Petit+Formal+Script" />
|
||
|
||
|
||
</head>
|
||
<body>
|
||
<a href="#main-content" class="visually-hidden focusable">
|
||
Skip to main content
|
||
</a>
|
||
<noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-T58NF4" height="0" width="0" style="display:none;visibility:hidden"></iframe>
|
||
</noscript>
|
||
|
||
<div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas>
|
||
<div class="layout-container">
|
||
<div>
|
||
<div id="block-nimhtheme-governmentdomainbanner" class="block block-block-content block-block-content976fab65-59c7-46e1-bf9f-cf5178b680b4">
|
||
|
||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><section class="usa-banner" aria-label="Official website of the United States government"><div class="usa-accordion"><header class="usa-banner__header"><div class="usa-banner__inner"><div class="grid-col-auto"><img class="usa-banner__header-flag" aria-hidden="true" src="/themes/nimhtheme/uswds/images/us_flag_small.png" alt></div><div class="grid-col-fill tablet:grid-col-auto" aria-hidden="true"><p class="usa-banner__header-text">An official website of the United States government</p><p class="usa-banner__header-action">Here’s how you know</p></div><p class="m-0 p-0"><button class="usa-accordion__button usa-banner__button" type="button" aria-expanded="false" aria-controls="gov-banner-default"><span class="usa-banner__button-text">Here’s how you know</span></button></p></div></header><div class="usa-banner__content usa-accordion__content" id="gov-banner-default" hidden><div class="grid-row grid-gap-lg"><div class="usa-banner__guidance tablet:grid-col-6"><p><img class="usa-banner__icon usa-media-block__img" src="/themes/nimhtheme/uswds/images/icon-dot-gov.svg" role="img" alt aria-hidden="true"></p><div class="usa-media-block__body"><p><strong>Official websites use .gov</strong><br>A <strong>.gov</strong> website belongs to an official government organization in the United States.</p></div></div><div class="usa-banner__guidance tablet:grid-col-6"><p><img class="usa-banner__icon usa-media-block__img" src="/themes/nimhtheme/uswds/images/icon-https.svg" role="img" alt aria-hidden="true"></p><div class="usa-media-block__body"><p><strong>Secure .gov websites use HTTPS</strong><br>A <strong>lock</strong> ( <span class="icon-lock"><svg class="usa-banner__lock-image" width="52" height="64" viewBox="0 0 52 64" role="img" aria-labelledby="banner-lock-description-default" focusable="false"><title id="banner-lock-title-default">Lock</title> <desc id="banner-lock-description-default">Locked padlock icon</desc> <path fill="#000000" fill-rule="evenodd" d="M26 0c10.493 0 19 8.507 19 19v9h3a4 4 0 0 1 4 4v28a4 4 0 0 1-4 4H4a4 4 0 0 1-4-4V32a4 4 0 0 1 4-4h3v-9C7 8.507 15.507 0 26 0zm0 8c-5.979 0-10.843 4.77-10.996 10.712L15 19v9h22v-9c0-6.075-4.925-11-11-11z" /></svg></span>) or <strong>https://</strong> means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.</p></div></div></div></div></div></section></div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
<div class="header-wrapper">
|
||
<div class="header-container">
|
||
<header role="banner">
|
||
<div id="main-header-layout" >
|
||
<div id="block-sitebranding-2" class="block block-system block-system-branding-block">
|
||
|
||
|
||
<a href="/" title="NIMH Home" rel="home">
|
||
<img src="/themes/nimhtheme/nimh-logo.svg" alt="NIMH Logo" />
|
||
</a>
|
||
|
||
</div>
|
||
<div id="block-nimhtheme-incrisisstickybox" class="block block-block-content block-block-content34cda229-f96b-4500-8796-12d7fc307d77">
|
||
|
||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><div id="nimh-in-crisis-callout"><a href="https://988lifeline.org/"><i class="fa-light fa-circle-exclamation" aria-hidden="true"></i> In Crisis? Call or Text 988 <i class="fa-regular fa-angles-right"></i></a></div></div>
|
||
|
||
</div>
|
||
<div id="block-tagline" class="block block-block-content block-block-contentf3b653dc-7e5d-4582-8234-a93001424fde">
|
||
|
||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><p id="tagline">Transforming the understanding
|
||
<br>
|
||
and treatment of mental illnesses.
|
||
</p></div>
|
||
|
||
</div>
|
||
<div id="block-nimhtheme-searchsite" class="block block-block-content block-block-content0946d2cf-ffcf-44fb-b65d-3057740945c0">
|
||
|
||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><p class="m-0 text-small text-right d-none d-lg-block"><a href="/">Home</a> | <a href="/site-info/contact-nimh" data-entity-type="node" data-entity-uuid="3b82dd34-6040-4763-a9ff-db0c3d5b6a38" data-entity-substitution="canonical">Contact Us</a> | <a href="/health/find-help" data-entity-type="node" data-entity-uuid="95a25c22-6bc4-4ac3-ad7b-d3aca76eaed0" data-entity-substitution="canonical">Help for Mental Illnesses</a></p><div class="mobile-helper-icons"><span class="hidden-md hidden-lg"><i class="fas fa-search search_icon"></i></span> <span class="menu_icon sb-toggle-right hidden-md hidden-lg"><i class="fas fa-bars"></i></span></div><form class="search-in-banner" accept-charset="UTF-8" action="/search-nimh" id="search_form" method="get" name="Search" role="search"><p class="mt-2 mb-1"><label for="query"><span class="hidden">Search the NIMH Website: </span></label><input class="searchbox usagov-search-autocomplete ui-autocomplete-input" aria-label="Search the NIMH website" autocomplete="off" id="query" name="query" placeholder="Search the NIMH website" type="text"> <input type="submit" value="Search"></p></form><div class="hidden-xs hidden-sm"><p class="small text-right m-0"><a href="/health/topics/espanol" data-entity-type="node" data-entity-uuid="d6df42f3-6876-496e-918c-cc34cc7681f7" data-entity-substitution="canonical" lang="es">Información en español</a></p></div></div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</header>
|
||
</div>
|
||
</div> <div id="menu_horizontal" class="primary-menu-container">
|
||
<div>
|
||
<nav id="block-nimhtheme-main-menu" role="navigation" aria-label="Main navigation" id="block-nimhtheme-main-menu">
|
||
|
||
|
||
|
||
|
||
<ul class="main-menu-content">
|
||
<li class="navmenu_link">
|
||
<a href="/health" class="main-menu__health" data-drupal-link-system-path="node/1925">Mental Health Information</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/get-involved" class="main-menu__getinvolved" data-drupal-link-system-path="node/2019">Get Involved</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/research" class="main-menu__research" data-drupal-link-system-path="node/7518">Research</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/funding" class="main-menu__funding" data-drupal-link-system-path="node/1128">Funding</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/news" class="main-menu__news" data-drupal-link-system-path="node/2128">News & Events</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about" class="main-menu__about" data-drupal-link-system-path="node/7558">About Us</a>
|
||
</li>
|
||
</ul>
|
||
<div class="megamenu_container">
|
||
<div id="health-megamenu" class="megamenu">
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/health/topics">
|
||
<h2>Health Topics</h2>
|
||
<p>NIMH offers expert-reviewed information on mental disorders and a range of topics.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/health/statistics">
|
||
<h2>Statistics</h2>
|
||
<p>NIMH statistics pages include statistics on the prevalence, treatment, and costs of mental illness for the population of the United States.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/health/publications">
|
||
<h2>Brochures and Fact Sheets</h2>
|
||
<p>Download, read, and order free NIMH brochures and fact sheets about mental disorders and related topics.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/health/find-help">
|
||
<h2>Help for Mental Illnesses</h2>
|
||
<p>If you or someone you know has a mental illness, there are ways to get help. Use these resources to find help for yourself, a friend, or a family member.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/health/trials">
|
||
<h2>Clinical Trials</h2>
|
||
<p>If you or a friend or family member are thinking about taking part in clinical research, this page contains basic information about clinical trials.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div id="getinvolved-megamenu" class="megamenu">
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/get-involved/public-involvement">
|
||
<h2>Stakeholder Engagement</h2>
|
||
<p>Find out how NIMH engages a range of stakeholder organizations as part of its efforts to ensure the greatest public health impact of the research we support.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/get-involved/connect-with-nimh">
|
||
<h2>Connect with NIMH</h2>
|
||
<p>Learn more about NIMH newsletters, public participation in grant reviews, research funding, clinical trials, the NIMH Gift Fund, and connecting with NIMH on social media. </p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/get-involved/digital-shareables">
|
||
<h2>Digital Shareables</h2>
|
||
<p>Use these free education and outreach materials in your community and on social media to spread the word about mental health and related topics.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/get-involved/science-education">
|
||
<h2>Science Education</h2>
|
||
<p>Use these free digital, outreach materials in your community and on social media to spread the word about mental health.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/get-involved/events">
|
||
<h2>Upcoming Observances and Related Events</h2>
|
||
<p>Get Involved observances calendar</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div id="research-megamenu" class="megamenu">
|
||
<div class="menu_flexbox_span6">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/research/research-funded-by-nimh">
|
||
<h2>Research Funded by NIMH</h2>
|
||
<p>NIMH supports research at universities, medical centers, and other institutions via grants, contracts, and cooperative agreements. Learn more about NIMH research areas, policies, resources, and initiatives.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span6">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/research/research-conducted-at-nimh">
|
||
<h2>Research Conducted at NIMH (Intramural Research Program)</h2>
|
||
<p>The Division of Intramural Research Programs (IRP) is the internal research division of the NIMH. Over 40 research groups conduct basic neuroscience research and clinical investigations of mental illnesses, brain function, and behavior at the NIH campus in Bethesda, Maryland. Learn more about research conducted at NIMH.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span6">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/research/priority-research-areas">
|
||
<h2>Priority Research Areas</h2>
|
||
<p>Learn about NIMH priority areas for research and funding that have the potential to improve mental health care over the short, medium, and long term.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span6">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/research/research-funded-by-nimh/research-resources">
|
||
<h2>Resources for Researchers</h2>
|
||
<p>Information about resources such as data, tissue, model organisms and imaging resources to support the NIMH research community.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div id="funding-megamenu" class="megamenu">
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/funding/opportunities-announcements">
|
||
<h2>Opportunities & Announcements</h2>
|
||
<p>Find all NIMH and cross-NIH funding opportunities.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/funding/funding-strategy-for-research-grants">
|
||
<h2>Funding Strategy for Grants</h2>
|
||
<p>Read more about the NIMH Strategic Plan for Research, Strategic Research Priorities, the anatomy of NIMH funding, and our yearly funding strategy for research grants.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/funding/grant-writing-and-application-process">
|
||
<h2>Application Process</h2>
|
||
<p>Explore the NIMH grant application process, including how to write your grant, how to submit your grant, and how the review process works.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/funding/managing-your-grant">
|
||
<h2>Managing Grants</h2>
|
||
<p>Learn about how NIMH manages research grants, including policies and reporting requirements.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/funding/clinical-research">
|
||
<h2>Clinical Research</h2>
|
||
<p>Find the latest NIH and NIMH policies, guidance, and resources for clinical research.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/funding/training">
|
||
<h2>Training</h2>
|
||
<p>Explore NIMH research training and career development opportunities.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/funding/sbir">
|
||
<h2>Small Business Research</h2>
|
||
<p>Learn about funding opportunities for small businesses.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner_extra">
|
||
<div class="menu_inner_pad">
|
||
<section class="box">
|
||
<h3>Quick Links</h3>
|
||
<p><a href="/funding/opportunities-announcements/funding-grant-news">Funding & Grant News</a></p>
|
||
<p><a href="/funding/opportunities-announcements/clinical-trials-foas">Support for Clinical Trials at NIMH</a></p>
|
||
</section>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div id="news-megamenu" class="megamenu">
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/news/science-updates">
|
||
<h2>Science Updates</h2>
|
||
<p>List of NIMH science updates including press releases, research highlights, and institute announcements.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/news/events">
|
||
<h2>Meetings and Events</h2>
|
||
<p>Details about upcoming events—including meetings, conferences, workshops, lectures, webinars, and chats—sponsored by NIMH.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/news/media">
|
||
<h2>Multimedia</h2>
|
||
<p>NIMH videos and podcasts featuring science news, lecture series, meetings, seminars, and special events.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/news/social-media">
|
||
<h2>Social Media</h2>
|
||
<p>The latest information and resources on mental disorders shared on X, Facebook, YouTube, LinkedIn, and Instagram.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/news/press-resources">
|
||
<h2>Press Resources</h2>
|
||
<p>Information about NIMH, research results, summaries of scientific meetings, and mental health resources.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/news/email-updates">
|
||
<h2>Email Updates</h2>
|
||
<p>Updates about mental health topics, including NIMH news, upcoming events, mental disorders, funding opportunities, and research.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/news/innovation-speaker-series">
|
||
<h2>Innovation Speaker Series</h2>
|
||
<p>An annual lecture series dedicated to innovation, invention, and scientific discovery.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span4">
|
||
<div class="menu_inner_extra">
|
||
<div class="menu_inner_pad">
|
||
<h3>Contact the Press Office</h3>
|
||
<p>301-443-4536</p>
|
||
<p><a class="single-link" href="mailto:NIMHpress@nih.gov">NIMHpress@nih.gov</a></p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div id="about-megamenu" class="megamenu">
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/about/director">
|
||
<h2>About the Acting NIMH Director</h2>
|
||
<p>Learn more about the Acting Director of the NIMH, Shelli Avenevoli, Ph.D.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/about/advisory-boards-and-groups">
|
||
<h2>Advisory Boards and Groups</h2>
|
||
<p>Read about the boards and groups that advise and provide guidance to the Institute.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/about/strategic-planning-reports">
|
||
<h2>Strategic Plan</h2>
|
||
<p>Learn more about NIMH's roadmap for the Institute’s research priorities over the next five years.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/about/organization">
|
||
<h2>Offices and Divisions</h2>
|
||
<p>Learn more about the functions of each NIMH office and division.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/about/budget">
|
||
<h2>Budget</h2>
|
||
<p>Read the annual NIMH Congressional Justifications.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/about/careers">
|
||
<h2>Careers at NIMH</h2>
|
||
<p>Search for jobs, including scientific, administrative and executive careers at NIMH.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/about/staff-directories">
|
||
<h2>Staff Directories</h2>
|
||
<p>Find the names, telephone numbers, email addresses, and office locations of NIMH staff.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/about/nimh-history">
|
||
<h2>History</h2>
|
||
<p>Explore key milestones, discoveries, and the impact of NIMH-funded studies on mental health.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner">
|
||
<a class="megamenu_nav_i" href="/about/connect-with-nimh">
|
||
<h2>Getting to NIMH</h2>
|
||
<p>Find directions, maps, parking information, and other visitor information for NIMH.</p>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="menu_flexbox_span3">
|
||
<div class="menu_inner_extra">
|
||
<div class="menu_inner_pad">
|
||
<h3>Quick Links</h3>
|
||
<p><strong><a href="/about/connect-with-nimh/donate-to-mental-health-research" title="Donate to Mental Health Research">Contribute to Mental Health Research</a></strong></p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
</nav>
|
||
<nav id="block-mobilenavigation" role="navigation" aria-label="Mobile navigation" id="block-mobilenavigation">
|
||
|
||
|
||
|
||
<p class="mobile-menu-close"><i class="fas fa-times fa-2x"></i></p>
|
||
<ul class="main-menu-content">
|
||
<li class="navmenu_link">
|
||
<a href="/health" class="mobile-menu-top-level health-menu" data-drupal-link-system-path="node/1925">Mental Health Information</a>
|
||
<ul>
|
||
<li class="navmenu_link">
|
||
<a href="/health" data-drupal-link-system-path="node/1925">Mental Health Information Home</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/health/topics" data-drupal-link-system-path="node/1926">Health Topics</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/health/statistics" data-drupal-link-system-path="node/1243">Statistics</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/health/publications" data-drupal-link-system-path="node/1927">Brochures and Fact Sheets</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/health/find-help" data-drupal-link-system-path="node/1944">Help for Mental Illnesses</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/health/trials" data-drupal-link-system-path="node/2009">Clinical Trials</a>
|
||
</li>
|
||
</ul>
|
||
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/get-involved" class="mobile-menu-top-level getinvolved-menu" data-drupal-link-system-path="node/2019">Get Involved</a>
|
||
<ul>
|
||
<li class="navmenu_link">
|
||
<a href="/get-involved" data-drupal-link-system-path="node/2019">Get Involved Home</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/get-involved/public-involvement" data-drupal-link-system-path="node/2127">Stakeholder Engagement</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/get-involved/connect-with-nimh" data-drupal-link-system-path="node/8488">Connect with NIMH</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/get-involved/digital-shareables" data-drupal-link-system-path="node/7521">Digital Shareables</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/get-involved/science-education" data-drupal-link-system-path="node/10164">Science Education</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/get-involved/events" data-drupal-link-system-path="node/8489">Upcoming Observances and Related Events</a>
|
||
</li>
|
||
</ul>
|
||
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/research" class="mobile-menu-top-level research-menu" data-drupal-link-system-path="node/7518">Research</a>
|
||
<ul>
|
||
<li class="navmenu_link">
|
||
<a href="/research" data-drupal-link-system-path="node/7518">Research Home</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/research/research-funded-by-nimh" data-drupal-link-system-path="node/1992">Research Funded by NIMH</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/research/research-conducted-at-nimh" data-drupal-link-system-path="node/1123">Research Conducted at NIMH (Intramural Research Program)</a>
|
||
</li>
|
||
</ul>
|
||
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/funding" class="mobile-menu-top-level funding-menu" data-drupal-link-system-path="node/1128">Funding</a>
|
||
<ul>
|
||
<li class="navmenu_link">
|
||
<a href="/funding" data-drupal-link-system-path="node/1128">Funding Home</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/funding/opportunities-announcements" data-drupal-link-system-path="node/1029">Opportunities & Announcements</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/funding/funding-strategy-for-research-grants/strategy-for-research-grants" data-drupal-link-system-path="node/1137">Strategy for Research Grants</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/funding/grant-writing-and-application-process" data-drupal-link-system-path="node/1995">Grant Writing & Approval Process</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/funding/managing-your-grant" data-drupal-link-system-path="node/1140">Managing Grants</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/funding/clinical-research" data-drupal-link-system-path="node/1190">Clinical Research</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/funding/training" data-drupal-link-system-path="node/2007">Research Training and Career Development Opportunities</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/funding/sbir" data-drupal-link-system-path="node/1674">Small Business Research</a>
|
||
</li>
|
||
</ul>
|
||
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/news" class="mobile-menu-top-level news-menu" data-drupal-link-system-path="node/2128">News & Events</a>
|
||
<ul>
|
||
<li class="navmenu_link">
|
||
<a href="/news" data-drupal-link-system-path="node/2128">News & Events Home</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/news/science-updates" data-drupal-link-system-path="node/4730">Science Updates</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/news/events" data-drupal-link-system-path="node/1986">Meetings and Events</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/news/media" data-drupal-link-system-path="node/5039">Multimedia</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/news/social-media" data-drupal-link-system-path="node/1659">Social Media</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/news/press-resources" data-drupal-link-system-path="node/1653">Press Resources</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/news/email-updates" data-drupal-link-system-path="node/2023">Email Updates</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/news/innovation-speaker-series" data-drupal-link-system-path="node/7539">Innovation Speaker Series</a>
|
||
</li>
|
||
</ul>
|
||
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about" class="mobile-menu-top-level about-menu" data-drupal-link-system-path="node/7558">About Us</a>
|
||
<ul>
|
||
<li class="navmenu_link">
|
||
<a href="/about" data-drupal-link-system-path="node/7558">About Us Home</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about/director" data-drupal-link-system-path="node/7459">About the Acting NIMH Director</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about/advisory-boards-and-groups" data-drupal-link-system-path="node/1964">Advisory Boards and Groups</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about/strategic-planning-reports" data-drupal-link-system-path="node/1959">Strategic Plan</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about/organization" data-drupal-link-system-path="node/1963">Offices and Divisions</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about/budget" data-drupal-link-system-path="node/1967">Budget</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about/careers" data-drupal-link-system-path="node/1960">Careers at NIMH</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about/staff-directories" data-drupal-link-system-path="node/2030">Staff Directories</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about/nimh-history" data-drupal-link-system-path="node/11838">History</a>
|
||
</li>
|
||
<li class="navmenu_link">
|
||
<a href="/about/connect-with-nimh" data-drupal-link-system-path="node/7564">Getting to NIMH</a>
|
||
</li>
|
||
</ul>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</nav>
|
||
|
||
</div>
|
||
|
||
</div> <div class="submenu">
|
||
<div class="container">
|
||
<div class="row">
|
||
<div class="col-md-12">
|
||
<ul class="group navbar">
|
||
<li class="span navbarli"><a href="/news/science-updates" class="navbari topnav subroot">Science Updates</a></li>
|
||
<li class="span navbarli"><a href="/news/events" class="navbari topnav subroot">Meetings and Events</a></li>
|
||
<li class="span navbarli"><a href="/news/media" class="navbari topnav subroot">Multimedia</a></li>
|
||
<li class="span navbarli"><a href="/news/social-media" class="navbari topnav subroot">Social Media</a></li>
|
||
<li class="span navbarli"><a href="/news/press-resources" class="navbari topnav subroot">Press Resources</a></li>
|
||
<li class="span navbarli"><a href="/news/email-updates" class="navbari topnav subroot">Email Updates</a></li>
|
||
<li class="span navbarli"><a href="/news/innovation-speaker-series" class="navbari topnav subroot">Innovation Speaker Series</a></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div>
|
||
<div data-drupal-messages-fallback class="hidden"></div>
|
||
|
||
</div>
|
||
<div id="wrapper" class="pt-3 pt-sm-3 pt-md-3 pt-lg-0">
|
||
<div class="container pt-5 pt-sm-5 pt-md-5 pt-lg-0">
|
||
<div class="row"><div class="col-md-12 hidden-xs"><div class="breadcrumbs"><nav id="breadcrumbs" class="breadcrumbs__nav" aria-label="breadcrumb links" data-dirids="2293 2764 3481"><a href="/" data-dirlevel="0">Home</a> > <a href="/news" data-refid="2128" data-dirlevel="1" data-dirid="2293" >News & Events</a> > <a href="/news/science-updates" data-refid="4730" data-dirlevel="2" data-dirid="2764" >Science Updates</a> > <a href="/news/science-updates/2024" data-refid="11428" data-dirlevel="3" data-dirid="3481" >Science Updates from 2024</a> > <span data-refid="11738" data-dirlevel="4" data-dirid="3481" data-isleaf="1">Youth With Conduct Disorder Show Widespread Differences in Brain Structure</span></nav></div></div></div>
|
||
<div id="main_container">
|
||
<section class="share_links_wrap">
|
||
<div class="share_links_wrap_inner">
|
||
<h6 class="share_links_header">Share Page</h6>
|
||
<div class="share_links">
|
||
<a href="https://www.facebook.com/dialog/share?app_id=1086499805165807&display=popup&href=https://www.nimh.nih.gov%2Fnews%2Fscience-updates%2F2024%2Fyouth-with-conduct-disorder-show-widespread-differences-in-brain-structure&redirect_uri=https://www.nimh.nih.gov%2Fnews%2Fscience-updates%2F2024%2Fyouth-with-conduct-disorder-show-widespread-differences-in-brain-structure" rel="external noopener noreferrer" target="_blank" class="external-disclaimer" aria-label="Share this page on Facebook"><span class="facebook-share"><i class="fab fa-facebook-f"></i></span></a>
|
||
<a href="https://x.com/intent/post?url=https://www.nimh.nih.gov%2Fnews%2Fscience-updates%2F2024%2Fyouth-with-conduct-disorder-show-widespread-differences-in-brain-structure&text=Youth%20With%20Conduct%20Disorder%20Show%20Widespread%20Differences%20in%20Brain%20Structure" rel="external noopener noreferrer" target="_blank" class="external-disclaimer" aria-label="Share this page on X"><span class="twitter-share"><i class="fab fa-x-twitter"></i></span></a>
|
||
<a href="https://www.linkedin.com/shareArticle?mini=true&url=https://www.nimh.nih.gov%2Fnews%2Fscience-updates%2F2024%2Fyouth-with-conduct-disorder-show-widespread-differences-in-brain-structure&title=Youth%20With%20Conduct%20Disorder%20Show%20Widespread%20Differences%20in%20Brain%20Structure" rel="external noopener noreferrer" target="_blank" class="external-disclaimer" aria-label="Share this page on LinkedIn"><span class="linkedin-share"><i class="fa-brands fa-linkedin-in"></i></span></a>
|
||
<a href="mailto:?subject=I%20Saw%20This%20on%20www.nimh.nih.gov%20--%20Youth%20With%20Conduct%20Disorder%20Show%20Widespread%20Differences%20in%20Brain%20Structure&body=https://www.nimh.nih.gov%2Fnews%2Fscience-updates%2F2024%2Fyouth-with-conduct-disorder-show-widespread-differences-in-brain-structure" aria-label="Share this page by email"><span class="email-share"><i class="fas fa-envelope"></i></span></a>
|
||
<button class="print_icon" aria-label="Open print helper modal"><i class="fas fa-print"></i></button>
|
||
</div>
|
||
</div>
|
||
</section>
|
||
<div class="row">
|
||
<div class="flex_main_container col-md-12">
|
||
<div class="visible-xs sidebar-menu-helper">
|
||
<p class="leftnav_menu_toggle sb-toggle-left">Menu <i class="fas fa-long-arrow-alt-right"
|
||
aria-hidden="true"></i></p>
|
||
</div>
|
||
<aside class="layout-sidebar-first" role="complementary">
|
||
<section class="navblock areanav_child">
|
||
<h2 class="navblock__header">Contact(s)</h2>
|
||
<p class="navblock__text"><span class="vcard"><span
|
||
class="fn org">NIMH Press Office</span><br> <span class="tel">301-443-4536</span><br> <a
|
||
href="mailto:NIMHpress@nih.gov">NIMHpress@nih.gov</a></span></p>
|
||
<br>
|
||
<p><a href="/news/press-resources">Press Resources</a></p>
|
||
</section>
|
||
<section class="navblock areanav_child">
|
||
<h2 class="navblock__header">More Science Updates about</h2>
|
||
<ul class="navblock__list">
|
||
<li class="navblock__list__item link-container"><a href="/news/science-updates/brain-anatomy-and-physiology"
|
||
class="single-link">Brain Anatomy and Physiology</a></li>
|
||
<li class="navblock__list__item link-container"><a href="/news/science-updates/children-and-adolescents"
|
||
class="single-link">Children and Adolescents</a></li>
|
||
|
||
</ul>
|
||
</section>
|
||
</aside>
|
||
<div id="main_content" class="areanav-true sidebar-false">
|
||
<main id="main-content">
|
||
<article id="main_content_inner">
|
||
<div id="block-nimhtheme-local-tasks"></div>
|
||
<div class="titleblock">
|
||
<h1 class="titleblock__title" id="title">Youth With Conduct Disorder Show Widespread Differences in Brain Structure</h1>
|
||
</div>
|
||
<p id="subtitle">NIH-funded study of conduct disorder identifies new brain areas associated with the disorder, offering future directions for research efforts and clinical practice</p>
|
||
|
||
<p class="pagestamp_news_wrap">
|
||
<time class="pagestamp_news_time" datetime="2024-07-17">July 17, 2024</time>
|
||
• <span class="pagestamp_news_type">Press Release</span></p>
|
||
|
||
<html><body><p>A neuroimaging study of young people who exhibit a persistent pattern of disruptive, aggressive, and antisocial behavior, known as conduct disorder, has revealed extensive changes in brain structure. The most pronounced difference was a smaller area of the brain’s outer layer, known as the cerebral cortex, which is critical for many aspects of behavior, cognition, and emotion. The study, co-authored by researchers at the National Institutes of Health (NIH), is published in <em>The Lancet Psychiatry</em>.</p><p>“Conduct disorder has among the highest burden of any mental disorder in youth. However, it remains understudied and undertreated. Understanding brain differences associated with the disorder takes us one step closer to developing more effective approaches to diagnosis and treatment, with the ultimate aim of improving long-term outcomes for children and their families,” said co-author Daniel Pine, M.D., Chief of the Section on Development and Affective Neuroscience in NIH’s National Institute of Mental Health. “Critical next steps are to follow children over time to determine if differences in brain structure seen in this study are a cause of conduct disorder or a long-term consequence of living with the disorder.”</p><p>A collaborative group of researchers examined standardized MRI data from youth ages 7 to 21 who had participated in 15 studies from around the world. Analyses compared the surface area and thickness of the cerebral cortex and the volume of deeper subcortical brain regions between 1,185 youth diagnosed with conduct disorder and 1,253 youth without the disorder. Additional analyses compared the cortical and subcortical brain measures between boys and girls, age of symptom onset (childhood vs. adolescence), and level of empathy and other prosocial traits (high vs. low).</p><p>Youth with conduct disorder had lower total surface area across the cortex and in 26 of 34 individual regions, two of which showed significant changes in cortical thickness. Youth with conduct disorder also had lower volume in several subcortical brain regions, including the amygdala, hippocampus, and thalamus, which play a central role in regulating behaviors that are often challenging for people with the disorder. Although some of these brain regions, like the prefrontal cortex and amygdala, had been linked to conduct disorder in previous studies, other regions were implicated in the disorder for the first time.</p><p>The associations with brain structure did not differ between boys and girls and were seen across conduct disorder subgroups based on age of onset and level of prosocial traits. Youth who exhibited signs of a more severe form of the disorder, indicated by a low level of empathy, guilt, and remorse, showed the greatest number of brain changes.</p><figure role="group">
|
||
<article class="media media--type-image media--view-mode-default">
|
||
|
||
|
||
|
||
<span class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/images/news-items/image-library/brain-plots-of-regions-with-significant-differences-between-youth-with-and-without-conduct-disorder.jpg" width="1218" height="757" alt="Three panels showing plots of the brain. Panel A shows mean cortical thickness, Panel B shows mean surface area, and Panel C shows mean subcortical volume.">
|
||
|
||
</span>
|
||
|
||
</article>
|
||
|
||
<figcaption>Brain plots showing regions with significant group differences between youth with and without conduct disorder. Credit: Gao, Staginnus, et al., <a href="https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(24)00187-1/fulltext"><em>The Lancet Psychiatry</em></a>.</figcaption>
|
||
</figure>
|
||
<p>These findings from the largest, most diverse, and most robust study of conduct disorder to date are consistent with a growing body of evidence that the disorder is related to the structure of the brain. The study also provides novel evidence that brain changes are more widespread than previously shown, spanning all four lobes and both cortical and subcortical regions. These findings offer new avenues for investigating potential causal links between differences in brain structure and symptoms of conduct disorder and for targeting brain regions as part of clinical efforts to improve diagnosis and treatment.</p><p>Yidian Gao, Ph.D., at the University of Birmingham and Marlene Staginnus, Ph.D., at the University of Bath co-led the study, which was conducted by the international <a href="https://enigma.ini.usc.edu/ongoing/enigma-antisocial-behavior/" rel="external noreferrer">Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA)–Antisocial Behavior <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a> working group. The ENIGMA consortium received funding from multiple NIH institutes through a cross-NIH alliance that funds the <a href="https://commonfund.nih.gov/bd2k/fundedresearch" rel="external">Big Data to Knowledge Centers of Excellence <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a>.</p><h2>Reference:</h2><p>Gao, Y., Staginnus, M., & the ENIGMA-Antisocial Behavior Working Group. (2024). Cortical structure and subcortical volumes in conduct disorder: A coordinated analysis of 15 international cohorts from the ENIGMA Antisocial Behavior working group. <em>The Lancet Psychiatry, 11,</em> 620-632. <a href="https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(24)00187-1/fulltext" rel="external noreferrer">https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(24)00187-1/fulltext <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a></p><h2>Grant:</h2><p><a href="https://reporter.nih.gov/search/tmmMbv2W7k63Xu2-7go7rA/project-details/9517044" rel="external">EB020403 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a></p></body>
|
||
</html>
|
||
<div class="prtag">###</div>
|
||
|
||
<html><body><p><strong>About the National Institute of Mental Health (NIMH):</strong> The mission of the
|
||
<abbr title="National Institute of Mental Health">NIMH
|
||
</abbr> is to transform the understanding and treatment of mental illnesses through basic and clinical research, paving the way for prevention, recovery and cure. For more information, visit the <a href="/">NIMH website</a>.
|
||
</p>
|
||
</body>
|
||
</html>
|
||
|
||
<html><body><p><strong>About the National Institutes of Health (NIH)</strong>: NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about <abbr title="National Institutes of Health">NIH</abbr> and its programs, visit the <a href="https://www.nih.gov" rel="external">NIH website <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a>.</p>
|
||
<p><em>NIH…Turning Discovery Into Health<sup>®<br></sup></em></p>
|
||
</body>
|
||
</html>
|
||
|
||
|
||
</article>
|
||
</main>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<footer id="footer-contact">
|
||
<div class="footer-container container">
|
||
<div>
|
||
<div id="block-contactusfooter" class="block block-block-content block-block-contentc7a9e7bc-56ff-41ac-8678-60f3a9a54eeb">
|
||
|
||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><h2>NIMH Information Resource Center</h2><div><span class="small">Available in English and español</span></div><div class="row"><div class="col-xl-6 col-lg-6 col-md-6 col-sm-6 col-xs-12"><p class="phone"><em><i class="fas fa-phone" aria-hidden="true"> </i></em> <strong>Phone: </strong> <a href="tel:1-866-615-6464">1-866-615-6464</a> <br><em><i class="far fa-comments" aria-hidden="true"> </i></em> <strong>Live Online Chat: </strong> <a href="https://infocenter.nimh.nih.gov">Talk to a representative</a> <br><em><i class="far fa-envelope" aria-hidden="true"> </i></em> <strong>Email: </strong> <a href="mailto:nimhinfo@nih.gov">nimhinfo@nih.gov</a> <br><em><i class="far fa-clock" aria-hidden="true"> </i></em><strong>Hours:</strong> 8:30 a.m. – 5 p.m. ET, M-F</p></div><div class="col-xl-6 col-lg-6 col-md-6 col-sm-6 col-xs-12"><p><strong>Mail: </strong> National Institute of Mental Health <br>Office of Science Policy, Planning, and Communications <br>6001 Executive Boulevard, MSC 9663 <br>Bethesda, MD 20892-9663</p></div></div></div>
|
||
|
||
</div>
|
||
<div id="block-nimhtheme-linkdisclaimer" class="block block-block-content block-block-content43e6eaa7-a06a-4a06-9eff-b06d3dded90d">
|
||
|
||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><div id="footer-disclaimer"><h2>Disclaimer</h2><p>We link to external websites for informational purposes only, but we do not endorse or guarantee their accuracy. Once you leave our site, you will be subject to the new website’s privacy policy. Read NIMH’s <a href="/site-info/policies#part_2717"><u>full external linking policy</u></a> for more information.</p></div></div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</footer>
|
||
|
||
<footer id="footer-social">
|
||
<div class="footer-container container">
|
||
<div>
|
||
<div id="block-followusfooter" class="block block-block-content block-block-contentcafb1a66-d0fb-4772-b5c2-5c7d0773f849">
|
||
|
||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><div class="row"><div class="col-lg-8 col-md-7 col-sm-12 followus"><h3>Follow Us</h3><p><a class="external-disclaimer" href="https://www.instagram.com/nimhgov/" title="NIMH Instagram" rel="external"><span class="hidden">Instagram</span><em><i class="fab fa-instagram" style="background:#005395;" aria-hidden="true"> </i></em></a> <a class="external-disclaimer" href="https://www.facebook.com/nimhgov" title="NIMH Facebook" rel="external"><span class="hidden">Facebook</span><em><i class="fab fa-facebook-f" style="background:#005395;" aria-hidden="true"> </i></em></a> <a class="external-disclaimer" href="https://www.linkedin.com/company/national-institute-of-mental-health-nimh" title="NIMH LinkedIn" rel="external"><span class="hidden">Linkedin</span><em><i class="fab fa-linkedin-in" style="background:#005395;" aria-hidden="true"> </i></em></a><a class="external-disclaimer" href="https://twitter.com/nimhgov" title="NIMH Twitter" rel="external"><span class="hidden">Twitter</span><em><i class="fab fa-x-twitter" style="background:#005395;" aria-hidden="true"> </i></em></a> <a class="external-disclaimer" href="https://www.youtube.com/nimhgov" title="NIMH YouTube" rel="external"><span class="hidden">YouTube</span><em><i class="fab fa-youtube" style="background:#005395;" aria-hidden="true"> </i></em></a><a href="/news/email-updates" title="NIMH Newsletters" data-entity-type="node" data-entity-uuid="72c6d25b-a844-48b0-be68-5c85cf5df771" data-entity-substitution="canonical"> <em><i class="far fa-file-alt" style="background:#005395;" aria-hidden="true"> </i></em></a><a href="/news/web-channels" title="NIMH News Feeds" data-entity-type="node" data-entity-uuid="26a1cafd-738b-443d-920f-c491f872d6d9" data-entity-substitution="canonical"> <em><i class="fas fa-rss" style="background:#005395;" aria-hidden="true"> </i></em></a></p></div><div class="col-lg-4 col-md-5 col-sm-12"><h3 class="mb-0">Subscribe to NIMH Email Updates</h3><form class="subscribe-in-banner" accept-charset="UTF-8" action="https://public.govdelivery.com/accounts/USNIMH/subscribers/qualify" method="get" name="Subscribe"><p><label><span class="hidden">Type email address...</span> <input class="subscribe_box" aria-label="Type email address..." name="email" placeholder="Type email address..." size="30" type="text"> </label><input type="submit" value="Subscribe"> </p></form></div></div><style>
|
||
.followus p a {
|
||
margin: .1rem;
|
||
}
|
||
.followus i.fab:hover, .followus i.far:hover, .followus i.fas:hover{
|
||
background-color: #00335e !important;
|
||
}
|
||
</style></div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</footer>
|
||
|
||
<footer id="footer-siteInfo">
|
||
<div class="footer-container container">
|
||
<div>
|
||
<div id="block-siteinfofooter" class="block block-block-content block-block-content7adf2027-35bd-4389-9dd4-330dcc3d17c4">
|
||
|
||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><div class="row" id="block-footer"><div class="col-xl-4 col-lg-4 col-md-4 col-sm-4 col-xs-12"><h5>NIMH Resources</h5><p><a href="/health/topics" data-entity-type="node" data-entity-uuid="f7e048e4-f68f-4b7f-afb8-6fb95336f6b3" data-entity-substitution="canonical">Health Topics</a> <br><a href="/health/publications" data-entity-type="node" data-entity-uuid="3a6321c0-9c96-45b6-8d5c-5f4eab17632b" data-entity-substitution="canonical">Brochures and Fact Sheets</a> <br><a href="/site-info/contact-nimh" data-entity-type="node" data-entity-uuid="3b82dd34-6040-4763-a9ff-db0c3d5b6a38" data-entity-substitution="canonical">Contact Us</a> <br><a href="/health/topics/espanol" data-entity-type="node" data-entity-uuid="d6df42f3-6876-496e-918c-cc34cc7681f7" data-entity-substitution="canonical">Información en español</a></p></div><div class="col-xl-4 col-lg-4 col-md-4 col-sm-4 col-xs-12"><h5>Policies and Notices</h5><p><a href="/site-info/privacy-policy" data-entity-type="node" data-entity-uuid="f9084068-f15e-4322-b69b-eb250f301bf4" data-entity-substitution="canonical">Privacy Policy</a> <br><a href="/site-info/policies" data-entity-type="node" data-entity-uuid="e7a9f3b0-b458-4dcd-84aa-2c373b217d3f" data-entity-substitution="canonical">Website Policies</a> <br><a href="http://www.nih.gov/icd/od/foia/index.htm" rel="external">FOIA <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon" aria-hidden="true"></i></a> <br><a href="/site-info/accessibility" data-entity-type="node" data-entity-uuid="35acaa5a-b4a3-4061-b0b9-018d0e02b011" data-entity-substitution="canonical">Accessibility</a> <br><a href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html" rel="external">HHS Vulnerability Disclosure <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon" aria-hidden="true"></i></a></p></div><div class="col-xl-4 col-lg-4 col-md-4 col-sm-4 col-xs-12"><h5>Federal Resources</h5><p><a href="http://www.nih.gov/" rel="external">National Institutes of Health (NIH) <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon" aria-hidden="true"></i></a> <br><a href="https://www.nih.gov/virtual-tour/" rel="external">NIH Virtual Tour <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon" aria-hidden="true"></i></a> <br><a href="https://www.hhs.gov" rel="external">U.S. Department of Health and Human Services <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon" aria-hidden="true"></i></a> <br><a href="http://www.usa.gov/" rel="external">USA.gov <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon" aria-hidden="true"></i></a></p></div></div><p class="institute_boilerplate">The National Institute of Mental Health (NIMH) is part of NIH, a component of the U.S. Department of Health and Human Services.</p></div>
|
||
|
||
</div>
|
||
<div id="block-backtotop" class="block block-block-content block-block-content2fd64a46-6d78-4c08-8260-bf3aad9aa46d">
|
||
|
||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><p class="hidden-sm hidden-xs" id="backtotop"><a href="#skipnav"><span class="bt-img"> </span><span>Top</span></a>
|
||
</p></div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</footer>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
<script src="/sites/default/files/js/js_Ar12EQc0ItFgOVOiA7ch7vfF-NWs4pUi1kGBcM1-7rw.js?scope=footer&delta=0&language=en&theme=nimhtheme&include=eJzLy8zNKMlIzU3VT8vPK0ksTy3Oz02NN9PJg4un5-QnJeboFicXZRaUFAMA0TwS7A"></script>
|
||
<script src="//kit.fontawesome.com/1ea3372bd6.js" crossorigin="anonymous"></script>
|
||
<script src="/sites/default/files/js/js_uIBU-5fuvQZZvnNDo5BMVNRXUN7VE0SzzMMTrzW1miA.js?scope=footer&delta=2&language=en&theme=nimhtheme&include=eJzLy8zNKMlIzU3VT8vPK0ksTy3Oz02NN9PJg4un5-QnJeboFicXZRaUFAMA0TwS7A"></script>
|
||
|
||
</body>
|
||
</html>
|