nih-gov/www.nih.gov/node/37216
2025-02-26 13:17:41 -05:00

569 lines
44 KiB
Text
Raw Permalink Blame History

This file contains invisible Unicode characters

This file contains invisible Unicode characters that are indistinguishable to humans but may be processed differently by a computer. If you think that this is intentional, you can safely ignore this warning. Use the Escape button to reveal them.

This file contains Unicode characters that might be confused with other characters. If you think that this is intentional, you can safely ignore this warning. Use the Escape button to reveal them.

<!DOCTYPE html>
<html class="no-js" lang="en" dir="ltr" prefix="content: http://purl.org/rss/1.0/modules/content/ dc: http://purl.org/dc/terms/ foaf: http://xmlns.com/foaf/0.1/ rdfs: http://www.w3.org/2000/01/rdf-schema# sioc: http://rdfs.org/sioc/ns# sioct: http://rdfs.org/sioc/types# skos: http://www.w3.org/2004/02/skos/core# xsd: http://www.w3.org/2001/XMLSchema#">
<head>
<title>Mediterranean diet may slow development of Alzheimers disease | National Institutes of Health (NIH)</title>
<meta charset="utf-8" />
<script type="text/javascript">
//<![CDATA[
var usasearch_config = { siteHandle:"nih" };
var script = document.createElement("script");
script.type = "text/javascript";
script.src = "//search.usa.gov/javascripts/remote.loader.js";
document.getElementsByTagName("head")[0].appendChild(script);
//]]>
</script><link rel="shortcut icon" href="https://www.nih.gov/favicon.ico" type="image/vnd.microsoft.icon" />
<meta name="google-site-verification" content="rjIoO4vW0AYgltSYvxM1L_CzGIkq28kHf9gHIASKx8s" />
<link rel="profile" href="http://www.w3.org/1999/xhtml/vocab" />
<meta http-equiv="cleartype" content="on" />
<link rel="apple-touch-icon" href="https://www.nih.gov/sites/all/themes/nih/apple-touch-icon.png" />
<meta name="description" content="Researchers found that eating a Mediterranean diet slows some changes in the brain that may indicate early Alzheimers disease." />
<meta name="keywords" content="Alzheimers, dementia, Mediterranean diet, cerebral cortex, beta-amyloid, β-amyloid, FDG-PET glucose metabolism, CMRglc, PiB-PET, Lisa Mosconi, Neurology" />
<meta name="robots" content="follow, index" />
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
<meta name="generator" content="Drupal 7 (http://drupal.org)" />
<link rel="canonical" href="https://www.nih.gov/news-events/nih-research-matters/mediterranean-diet-may-slow-development-alzheimers-disease" />
<link rel="shortlink" href="https://www.nih.gov/node/37216" />
<meta http-equiv="content-language" content="EN" />
<meta property="og:site_name" content="National Institutes of Health (NIH)" />
<meta property="og:type" content="article" />
<meta property="og:title" content="Mediterranean diet may slow development of Alzheimers disease" />
<meta property="og:url" content="https://www.nih.gov/news-events/nih-research-matters/mediterranean-diet-may-slow-development-alzheimers-disease" />
<meta property="og:description" content="Researchers found that eating a Mediterranean diet slows some changes in the brain that may indicate early Alzheimers disease." />
<meta property="og:updated_time" content="2018-05-22T11:52:17-04:00" />
<meta property="og:image:url" content="https://www.nih.gov/sites/default/files/news-events/research-matters/2018/20180510-alzheimers.jpg" />
<meta name="twitter:card" content="summary" />
<meta name="twitter:title" content="Mediterranean diet may slow development of Alzheimers disease" />
<meta name="twitter:url" content="https://www.nih.gov/news-events/nih-research-matters/mediterranean-diet-may-slow-development-alzheimers-disease" />
<meta name="twitter:description" content="Researchers found that eating a Mediterranean diet slows some changes in the brain that may indicate early Alzheimers disease." />
<meta property="article:published_time" content="2018-05-14T14:35:10-04:00" />
<meta property="article:modified_time" content="2018-05-22T11:52:17-04:00" />
<meta name="owner" content="OD" />
<meta name="published_date" content="2018-05-14T14:35:10-04:00" />
<meta name="last_revision" content="2018-05-22T11:52:17-04:00" />
<link type="text/css" rel="stylesheet" href="https://www.nih.gov/sites/default/files/css/css_PfvPCWanzn7FjDwZqwAHhPoOxYKwkQP-RZSK1pFFG0s.css" media="all" />
<link type="text/css" rel="stylesheet" href="https://www.nih.gov/sites/default/files/css/css__mIWP9gcStq74isjZVoAAsiih8VXwJoN75Nyw_BXrj0.css" media="screen" />
<style media="print">#sb-container{position:relative;}#sb-overlay{display:none;}#sb-wrapper{position:relative;top:0;left:0;}#sb-loading{display:none;}
</style>
<link type="text/css" rel="stylesheet" href="https://www.nih.gov/sites/default/files/css/css_jENQOQqZCRFGZK__DTefxYiXR2RUf03k1ugj3_Vg7vk.css" media="all" />
<link type="text/css" rel="stylesheet" href="//cdn.jsdelivr.net/qtip2/3.0.3/jquery.qtip.min.css" media="all" />
<link type="text/css" rel="stylesheet" href="https://www.nih.gov/sites/default/files/css/css_3yt-b0M1HNJsvKsXwYjh5TEtX2lJGAvJvtmVAfORYZs.css" media="all" />
<link type="text/css" rel="stylesheet" href="//fonts.googleapis.com/css?family=Droid+Sans:700,regular|Droid+Serif:italic,regular&amp;subset=latin" media="all" />
<link type="text/css" rel="stylesheet" href="https://www.nih.gov/sites/default/files/css/css_E4VlyxyL3JMcT6dslWLGb0uQdoI2bh_Xj0N65V-bcWo.css" media="all" />
<link type="text/css" rel="stylesheet" href="https://www.nih.gov/sites/default/files/css/css_5rDMv37-JxnNA70cRr_1jlAjVs56DCb8EN4XB2QLl0c.css" media="all" />
<!--[if lte IE 8]>
<link type="text/css" rel="stylesheet" href="https://www.nih.gov/sites/default/files/css/css_aLJB_yHt22A_mQek4IRDNsur5tEkCpqLe72j_w6QHQ0.css" media="all" />
<![endif]-->
<link type="text/css" rel="stylesheet" href="https://www.nih.gov/sites/default/files/css/css_KviiBystpJcQq4MplcQZvCFxnu9V763f5bPq_AKh4xM.css" media="all" />
<script src="https://www.nih.gov/sites/default/files/js/js_mQAv54bz2JVXcwS5QWlz0fVY9Os67zeu9bgNqtlVLPY.js"></script>
<script src="//code.jquery.com/jquery-2.2.4.min.js"></script>
<script>window.jQuery || document.write("<script src='/sites/all/modules/contrib/jquery_update/replace/jquery/2.2/jquery.min.js'>\x3C/script>")</script>
<script>jQuery.migrateMute=true;jQuery.migrateTrace=false;</script>
<script src="//code.jquery.com/jquery-migrate-1.4.1.min.js"></script>
<script>window.jQuery && window.jQuery.migrateWarnings || document.write("<script src='/sites/all/modules/contrib/jquery_update/replace/jquery-migrate/1.4.1/jquery-migrate.min.js'>\x3C/script>")</script>
<script src="https://www.nih.gov/sites/default/files/js/js_9sGTPBGcOGZjLiSLGrYEnuUf8VdvLmL_DEZNNNbnHXk.js"></script>
<script src="https://www.nih.gov/sites/default/files/js/js_hNnF7a_sbk6nZ2-mOamHzalYND7HBHDLRInsaU93HDk.js"></script>
<script>document.createElement( "picture" );</script>
<script src="https://www.nih.gov/sites/default/files/js/js_gHk2gWJ_Qw_jU2qRiUmSl7d8oly1Cx7lQFrqcp3RXcI.js"></script>
<script src="//cdn.jsdelivr.net/qtip2/3.0.3/jquery.qtip.min.js"></script>
<script defer="defer" src="//script.crazyegg.com/pages/scripts/0011/2616.js"></script>
<script src="https://www.nih.gov/sites/default/files/js/js_3s0l7MQ3oYmGkNAypyzCJq3a0wT85XX_P1SLgnph5K4.js"></script>
<script>
Shadowbox.path = "/sites/all/libraries/shadowbox/";
</script>
<script>jQuery.extend(Drupal.settings, {"basePath":"\/","pathPrefix":"","setHasJsCookie":0,"instances":"{\u0022default\u0022:{\u0022content\u0022:{\u0022text\u0022:\u0022\u0022},\u0022style\u0022:{\u0022tip\u0022:false,\u0022classes\u0022:\u0022\u0022},\u0022position\u0022:{\u0022at\u0022:\u0022bottom right\u0022,\u0022adjust\u0022:{\u0022method\u0022:\u0022\u0022},\u0022my\u0022:\u0022top left\u0022,\u0022viewport\u0022:false},\u0022show\u0022:{\u0022event\u0022:\u0022mouseenter \u0022},\u0022hide\u0022:{\u0022event\u0022:\u0022mouseleave \u0022}}}","qtipDebug":"{\u0022leaveElement\u0022:0}","shadowbox":{"animate":true,"animateFade":true,"animSequence":"wh","auto_enable_all_images":1,"auto_gallery":1,"autoplayMovies":true,"continuous":false,"counterLimit":10,"counterType":"default","displayCounter":true,"displayNav":true,"enableKeys":true,"fadeDuration":0.34999999999999998,"handleOversize":"resize","handleUnsupported":"link","initialHeight":160,"initialWidth":320,"language":"en","modal":false,"overlayColor":"#000","overlayOpacity":0.80000000000000004,"resizeDuration":0.55000000000000004,"showMovieControls":true,"slideshowDelay":0,"viewportPadding":20,"useSizzle":false},"picture":{"mappings":[["Sidebar media mappings","sidebar_media_mappings"],["Floated media mappings","floated_media_mappings"],["Not Set","not_set"]],"label":"Image size (required)"},"extlink":{"extTarget":"_blank","extClass":"ext","extLabel":"(link is external)","extImgClass":0,"extIconPlacement":0,"extSubdomains":1,"extExclude":"(.\\.nih\\.gov.)|(.\\.cancer\\.gov.)|(.\\.genome\\.gov.)|(.\\.drugabuse\\.gov.)|(locatorplus\\.gov.)|(.\\.govdelivery\\.com.)|(.\\.hatchbuck\\.com.)|(nihseniorhealth\\.gov.)|(clinicaltrials\\.gov.)|(search\\.usa\\.gov\\\/search\\?affiliate\\=hip.)|(search\\.gov\\\/search\\?affiliate\\=hip.)|(drugabuse\\.gov.)|(medlineplus\\.gov.)|(collegedrinkingprevention\\.gov.)|(smokefree\\.gov.)|(arpa-h\\.gov.)|(nih\\.sharepoint\\.com)","extInclude":"(.\\.pagefreezer\\.com.)","extCssExclude":".media, .emergency-message, .slideshow-main, .bean-home-slideshow-2l-block","extCssExplicit":"","extAlert":"_blank","extAlertText":"You are leaving the NIH website.\r\n\r\nThis external link provides additional information that is consistent with the intended purpose of this site. NIH cannot attest to the accuracy of a non-federal site.\r\n\r\nLinking to a non-federal site does not constitute an endorsement by NIH or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site\u2019s privacy policy when you follow the link.","mailtoClass":"mailto","mailtoLabel":"(link sends e-mail)","extUseFontAwesome":0}});</script>
<script type="application/javascript" id="uws-snippet">
// Verint Unified WebSDK Integration Snippet v2.3
//
// Instructions: please embed this snippet directly into every page of your website template.
// For optimal performance, this should be embedded directly into the template, not referenced as
// an external file.
//
// DO NOT MODIFY BELOW THIS LINE *****************************************
(function () {
var cookies = document.cookie.split("; ").reduce(function (o, i) { var p = i.split("="); o[p[0]] = p[1]; return o; }, {});
var containerValue = cookies.uws_container_override && JSON.parse(decodeURIComponent(cookies.uws_container_override));
var config = {
moduleHost: "ucm-us.verint-cdn.com",
configHost: "ucm-us.verint-cdn.com",
siteKey: "nih-gov",
container: containerValue || "live",
loadTime: Date.now()
};
var readyCallbacks = []; window.uwsReady = function (callback) { readyCallbacks.push(callback); };
var sdkPath = "//" + [config.moduleHost, "files/sites", config.siteKey, config.container, "sdk.js"].join("/");
var script = document.createElement("script"); script.src = sdkPath; script.async = true; script.type = "module";
script.addEventListener("load", function () { window.unifiedSDK.start(config, readyCallbacks); });
document.head.appendChild(script);
})();
// DO NOT MODIFY ABOVE THIS LINE *****************************************
</script>
</head>
<body class="html not-front not-logged-in page-node page-node- page-node-37216 node-type-nih-research-matters section navigation-nih-research-matters section-news-events">
<a href="#main-content" class="element-invisible element-focusable">Skip to main content</a>
<noscript aria-hidden="true"><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-5CBCNW2" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>
<div class="l-page has-one-sidebar has-sidebar-second">
<div class="l-page-content">
<header class="l-header" role="banner">
<div class="l-ribbon-wrapper">
<ul class="l-ribbon">
<li><span class="ribbon-hhs"></span><a href="https://www.hhs.gov">U.S. Department of Health &amp; Human Services</a><span class="ribbon-right"></span></li>
</ul>
</div> <div class="l-banner-wrapper">
<div class="l-banner">
<div class="l-branding">
<a class="nih-logo icon-nih-logo" href="/" title="National Institutes of Health (NIH) - Turning Discovery into Health" rel="home"><img src="/sites/all/themes/nih/images/nih-logo-color.png" width="390" height="60" alt="National Institutes of Health (NIH) - Turning Discovery into Health" /></a>
</div>
<!-- DigitalGov Search -->
<form accept-charset="UTF-8" action="https://search.nih.gov/search" id="search" class="search-form site-search" method="get">
<div style="margin:0;padding:0;display:inline"><input name="utf8" type="hidden" value="&#x2713;" /></div>
<input id="affiliate" name="affiliate" type="hidden" value="nih" />
<label for="query" class="hide">Search the NIH Website</label>
<input autocomplete="on" class="usagov-search-autocomplete form-field form-field-site-search" id="query" name="query" type="text" placeholder="Search NIH" /><input type="submit" name="commit" value="Search" class="form-button form-button-site-search" />
</form>
<ul class="banner-utilities">
<li><a href="/virtual-tour">Virtual Tour</a></li>
<li><a href="https://ned.nih.gov/">Staff Directory</a></li>
<li><a href="https://salud.nih.gov">En Espa&ntilde;ol</a></li>
</ul>
</div>
</div>
</header>
<div class="l-navigation-wrapper">
<!-- ****************** SITE MENU ****************** -->
<h2 class="element-invisible">Site Menu</h2>
<nav class="l-menu-wrapper">
<ul class="l-menu">
<!-- ********* HOME TAB (Mobile view only) ********* -->
<li class="tab-wrapper tab-wrapper-home">
<div class="tab home"><a href="/"><span>Home</span></a></div>
</li>
<!-- ********* HEALTH INFO TAB ********* -->
<li class="tab-wrapper tab-wrapper-healthinfo tab-wrapper-left">
<div class="tab"><a href="/health-information"><span>Health Information</span></a></div>
<div class="megamenu">
<div class="megamenu-col megamenu-leftcol">
<ul class="sub-menu">
<li><a href="https://www.hhs.gov/programs/social-services/health-care-facilities/index.html">Health Care Providers & Facilities</a></li>
<li><a href="/health-information/health-info-lines">Health Info Lines</a></li>
<li><a href="https://www.healthcare.gov">HealthCare.gov</a></li>
<li><a href="/research-training/science-education">Science Education Resources</a></li>
<li><a href="/health-information/nih-clinical-research-trials-you">NIH Clinical Research Trials and You</a></li>
<li><a href="/institutes-nih/nih-office-director/office-communications-public-liaison/clear-communication/talking-your-doctor">Talking to Your Doctor</a></li>
<!--<li><a href="/institutes-nih/nih-office-director/office-communications-public-liaison/clear-communication/clear-health-nih" title="">Clear Health AZ</a></li>-->
</ul>
<p class="more-wrapper"><a class="button gold" href="/health-information" title="More Health Information">More &raquo;</a></p>
</div>
<div class="megamenu-col megamenu-rightcol">
<form id="hipsearch" accept-charset="UTF-8" action="https://search.nih.gov/search" method="get" class="search-form">
<p class="subhead"><label for="query2">Search Health Topics</label></p>
<div class="input-wrapper">
<div style="margin:0;padding:0;display:inline"><input name="utf8" type="hidden" value="&#x2713;" /></div>
<input id="affiliate" name="affiliate" type="hidden" value="hip" />
<input type="hidden" name="dc" value="940" />
<input autocomplete="on" maxlength="50" class="usagov-search-autocomplete form-field form-field-search" id="query2" name="query" type="text" />
<input name="commit" type="submit" value="Go" id="searchbutton" class="form-button" />
</div>
</form>
<p class="subhead">Quick Links</p>
<ul class="sub-menu">
<li><a class="minibadge minibadge-medlineplus" href="https://medlineplus.gov/"><span class="minibadge-text">MedlinePlus Health Info</span></a></li>
<li><a class="minibadge minibadge-newsinhealth" href="https://newsinhealth.nih.gov/"><span class="minibadge-text">NIH News in Health</span></a></li>
<li><a class="minibadge minibadge-wellnesstoolkits" href="/health-information/your-healthiest-self-wellness-toolkits"><span class="minibadge-text">Wellness Toolkits</span></a></li>
</ul>
</div>
</div>
</li>
<!-- ********* GRANTS TAB ********* -->
<li class="tab-wrapper tab-wrapper-grants tab-wrapper-left">
<div class="tab"><a href="/grants-funding"><span>Grants & Funding</span></a></div>
<div class="megamenu">
<div class="megamenu-col megamenu-leftcol">
<ul>
<li><a href="https://grants.nih.gov">Grants Home Page</a></li>
<li><a href="https://grants.nih.gov/funding/index.htm">Find Funding</a></li>
<li><a href="https://grants.nih.gov/grants/how-to-apply-application-guide/due-dates-and-submission-policies/due-dates.htm">Due Dates</a></li>
<li><a href="https://grants.nih.gov/grants/how-to-apply-application-guide.html">How to Apply</a></li>
<li><a href="https://grants.nih.gov/grants/about_grants.htm">About Grants</a></li>
<li><a href="https://grants.nih.gov/policy/index.htm">Policy &amp; Compliance</a></li>
<li><a href="https://nexus.od.nih.gov/all/">Grants News/Blog</a></li>
<li><a href="https://grants.nih.gov/funding/contracts.htm">Contracts</a></li>
<li><a href="https://www.lrp.nih.gov/">Loan Repayment</a></li>
</ul>
<p class="more-wrapper"><a class="button gold" href="/grants-funding" title="More Grants &amp; Funding Information">More &raquo;</a></p>
</div>
<div class="megamenu-col megamenu-rightcol">
<p class="subhead">Quick Links</p>
<ul>
<li><a class="minibadge minibadge-report" href="https://report.nih.gov/"><span class="minibadge-text">RePORT</span></a></li>
<li><a class="minibadge minibadge-era" href="https://commons.era.nih.gov/commons/"><span class="minibadge-text">eRA Commons</span></a></li>
<li><a class="minibadge minibadge-commonfund" href="https://commonfund.nih.gov/"><span class="minibadge-text">NIH Common Fund</span></a></li>
</ul>
</div>
</div>
</li>
<!-- ********* NEWS TAB ********* -->
<li class="tab-wrapper tab-wrapper-news tab-wrapper-left">
<div class="tab"><a href="/news-events"><span>News &amp; Events</span></a></div>
<div class="megamenu">
<div class="megamenu-col megamenu-leftcol">
<ul>
<li><a href="/news-events/news-releases">News Releases</a></li>
<li><a href="/news-events/digital-media-kits">Digital Media Kits</a></li>
<li><a href="/news-events/media-resources">Media Resources</a></li>
<li><a href="/news-events/media-contacts">Media Contacts</a></li>
<li><a href="/news-events/images-b-roll">Images and B-roll</a></li>
<li><a href="/news-events/events">Events</a></li>
<li><a href="/news-events/social-media-outreach">Social Media</a></li>
</ul>
<p class="more-wrapper"><a class="button gold" href="/news-events" title="More News &amp; Events">More &raquo;</a></p>
</div>
<div class="megamenu-col megamenu-rightcol">
<p class="subhead">Quick Links</p>
<ul>
<li><a class="minibadge minibadge-newsinhealth" href="https://newsinhealth.nih.gov/"><span class="minibadge-text">NIH News in Health</span></a></li>
<li><a class="minibadge minibadge-researchmatters" href="/news-events/nih-research-matters"><span class="minibadge-text">NIH Research Matters</span></a></li>
<li><a class="minibadge minibadge-nihrecord" href="https://nihrecord.nih.gov/"><span class="minibadge-text">NIH Record</span></a></li>
</ul>
</div>
</div>
</li>
<!-- ********* RESEARCH TAB ********* -->
<li class="tab-wrapper tab-wrapper-research tab-wrapper-right">
<div class="tab"><a href="/research-training"><span>Research &amp; Training</span></a></div>
<div class="megamenu">
<div class="megamenu-col megamenu-leftcol">
<ul>
<li><a href="/research-training/medical-research-initiatives">Medical Research Initiatives</a></li>
<li><a href="/research-training/science-highlights">Science Highlights</a></li>
<li><a href="/research-training/science-education">Science Education</a></li>
<li><a href="/research-training/research-nih-labs-clinics">Research in NIH Labs &amp; Clinics</a></li>
<li><a href="/research-training/training-opportunities">Training Opportunities</a></li>
<li><a href="/research-training/library-resources">Library Resources</a></li>
<li><a href="/research-training/research-resources">Research Resources</a></li>
<li><a href="/research-training/clinical-research-resources">Clinical Research Resources</a></li>
<li><a href="/research-training/safety-regulation-guidance">Safety, Regulation and Guidance</a></li>
</ul>
<p class="more-wrapper"><a class="button gold" href="/research-training" title="More Research &amp; Training">More &raquo;</a></p>
</div>
<div class="megamenu-col megamenu-rightcol">
<p class="subhead">Quick Links</p>
<ul>
<li><a class="minibadge minibadge-pubmed" href="https://pubmed.ncbi.nlm.nih.gov"><span class="minibadge-text">PubMed</span></a></li>
<li><a class="minibadge minibadge-stemcell" href="https://stemcells.nih.gov"><span class="minibadge-text">Stem Cell Information</span></a></li>
<li><a class="minibadge minibadge-oppnet" href="https://oppnet.nih.gov"><span class="minibadge-text">OppNet</span></a></li>
<li><a class="minibadge minibadge-nidb" href="https://intramural.nih.gov"><span class="minibadge-text">NIDB</span></a></li>
<li><a class="minibadge minibadge-nihblueprint" href="https://neuroscienceblueprint.nih.gov"><span class="minibadge-text">NIH Blueprint for Neuroscience Research</span></a></li>
</ul>
</div>
</div>
</li>
<!-- ********* INSTITUTES TAB ********* -->
<li class="tab-wrapper tab-wrapper-institutes tab-wrapper-right">
<div class="tab"><a href="/institutes-nih"><span>Institutes at NIH</span></a></div>
<div class="megamenu">
<div class="megamenu-col megamenu-leftcol">
<ul>
<li><a href="/institutes-nih/list-institutes-centers">List of Institutes and Centers</a></li>
<li><a href="/institutes-nih/nih-office-director">NIH Office of the Director</a></li>
<li><a href="/institutes-nih/directors-nih-institutes-centers">Directors of NIH Institutes and Centers</a></li>
<li><a href="/institutes-nih/nih-institute-center-contact-information">NIH Institute and Center Contact Information</a></li>
</ul>
<p class="more-wrapper"><a class="button gold" href="/institutes-nih" title="More About the Institutes at NIH">More &raquo;</a></p>
</div>
<div class="megamenu-col megamenu-rightcol">
<p class="subhead">Quick Links</p>
<ul class="ic-acronymn-list">
<li><a href="https://www.cancer.gov" title="National Cancer Institute">NCI</a></li>
<li><a href="https://nei.nih.gov" title="National Eye Institute">NEI</a></li>
<li><a href="https://www.nhlbi.nih.gov" title="National Heart, Lung, and Blood Institute">NHLBI</a></li>
<li><a href="https://www.genome.gov" title="National Human Genome Research Institute">NHGRI</a></li>
<li><a href="https://www.nia.nih.gov" title="National Institute on Aging">NIA</a></li>
<li><a href="https://www.niaaa.nih.gov" title="National Institute on Alcohol Abuse and Alcoholism">NIAAA</a></li>
<li><a href="https://www.niaid.nih.gov" title="National Institute of Allergy and Infectious Diseases">NIAID</a></li>
<li><a href="https://www.niams.nih.gov" title="National Institute of Arthritis and Musculoskeletal and Skin Diseases">NIAMS</a></li>
<li><a href="https://www.nibib.nih.gov" title="National Institute of Biomedical Imaging and Bioengineering">NIBIB</a></li>
<li><a href="https://www.nichd.nih.gov" title="Eunice Kennedy Shriver National Institute of Child Health and Human Development">NICHD</a></li>
<li><a href="https://www.nidcd.nih.gov" title="National Institute on Deafness and Other Communication Disorders">NIDCD</a></li>
<li><a href="https://www.nidcr.nih.gov" title="National Institute of Dental and Craniofacial Research">NIDCR</a></li>
<li><a href="https://www.niddk.nih.gov" title="National Institute of Diabetes and Digestive and Kidney Diseases">NIDDK</a></li>
<li><a href="https://nida.nih.gov" title="National Institute on Drug Abuse">NIDA</a></li>
<li><a href="https://www.niehs.nih.gov" title="National Institute of Environmental Health Sciences">NIEHS</a></li>
<li><a href="https://www.nigms.nih.gov" title="National Institute of General Medical Sciences">NIGMS</a></li>
<li><a href="https://www.nimh.nih.gov" title="National Institute of Mental Health">NIMH</a></li>
<li><a href="https://www.nimhd.nih.gov" title="National Institute on Minority Health and Health Disparities">NIMHD</a></li>
<li><a href="https://www.ninds.nih.gov" title="National Institute of Neurological Disorders and Stroke">NINDS</a></li>
<li><a href="https://www.ninr.nih.gov" title="National Institute of Nursing Research">NINR</a></li>
<li><a href="https://www.nlm.nih.gov" title="National Library of Medicine">NLM</a></li>
<li><a href="https://www.cc.nih.gov" title="NIH Clinical Center">CC</a></li>
<li><a href="https://www.cit.nih.gov" title="Center for Information Technology">CIT</a></li>
<li><a href="https://www.csr.nih.gov" title="Center for Scientific Review">CSR</a></li>
<li><a href="https://www.fic.nih.gov" title="Fogarty International Center">FIC</a></li>
<li><a href="https://ncats.nih.gov" title="National Center for Advancing Translational Sciences">NCATS</a></li>
<li><a href="https://nccih.nih.gov" title="National Center for Complementary and Integrative Health">NCCIH</a></li>
</ul>
</div>
</div>
</li>
<!-- ********* ABOUT TAB ********* -->
<li class="tab-wrapper tab-wrapper-about tab-wrapper-right">
<div class="tab"><a href="/about-nih"><span>About NIH</span></a></div>
<div class="megamenu">
<div class="megamenu-col megamenu-leftcol">
<ul>
<li><a href="/about-nih/who-we-are">Who We Are</a></li>
<li><a href="/about-nih/what-we-do">What We Do</a></li>
<li><a href="https://hr.nih.gov/jobs">Jobs at NIH</a></li>
<li><a href="/about-nih/visitor-information">Visitor Information</a></li>
<li><a href="/about-nih/frequently-asked-questions">Frequently Asked Questions</a></li>
<li><a href="/about-nih/contact-us">Contact Us</a></li>
<!--<li><a href="/about-nih/explore-nih">Explore NIH</a></li>-->
</ul>
<p class="more-wrapper"><a class="button gold" href="/about-nih" title="More About NIH">More &raquo;</a></p>
</div>
<div class="megamenu-col megamenu-rightcol">
<p class="subhead">Quick Links</p>
<ul>
<li><a href="/about-nih/who-we-are/nih-director">The NIH Director</a></li>
<li><a href="/virtual-tour">Take the Virtual Tour</a></li>
<li><a href="/about-nih/what-we-do/nih-turning-discovery-into-health">NIH&hellip;Turning Discovery Into Health<sup>&reg;</sup></a></li>
<li><a href="/about-nih/what-we-do/impact-nih-research">Impact of NIH Research</a></li>
<li><a href="/about-nih/what-we-do/science-health-public-trust">Science, Health, and Public Trust</a></li>
</ul>
</div>
</div>
</li>
</ul>
<div class="tab-bkgnd"></div><!-- For pixel rounding issue -->
</nav>
<!-- ****************** END SITE MENU ****************** -->
</div>
<div class="l-main-wrapper">
<div class="l-main" id="page-content">
<h2 class="element-invisible">You are here</h2><div class="breadcrumb"><a href="/">Home</a> » <a href="/news-events">News &amp; Events</a> » <a href="/news-events/nih-research-matters">NIH Research Matters</a></div> <div class="l-region l-region--section-header">
<div id="block-block-101" class="block block--block sectionheader block--block-101" id="block-block-101" class="block block--block sectionheader block--block-101">
<div class="content" class="block__content">
<h2><a href="/news-events/nih-research-matters">NIH Research Matters</a></h2> </div>
</div>
</div>
<div class="l-content-wrapper">
<div class="l-content" role="main">
<a id="main-content"></a>
<div about="/news-events/nih-research-matters/mediterranean-diet-may-slow-development-alzheimers-disease" typeof="sioc:Item foaf:Document" class="ds-1col node node--nih-research-matters view-mode-full node--full node--nih-research-matters--full clearfix">
<p class="publishdate"><span property="dc:date" datatype="xsd:dateTime" content="2018-05-15T00:00:00-04:00" class="date-display-single">May 15, 2018</span></p><div class='syndicate'><h1>Mediterranean diet may slow development of Alzheimers disease </h1><div class="callout callout-with-border"><h3>At a Glance</h3>
<ul>
<li>Researchers found that eating a Mediterranean diet slows some changes in the brain that may indicate early Alzheimers disease.</li>
<li>The results point to a lifestyle change that could help reduce the risk of this type of age-related dementia.</li>
</ul></div><div class="media-float-right"><div class="media media-element-container media-shadowbox_sidebar"><div class="ds-1col file file-image file-image-jpeg view-mode-shadowbox_sidebar clearfix">
<a href="https://www.nih.gov/sites/default/files/news-events/research-matters/2018/20180510-alzheimers.jpg"><img class="sb-image sb-individual media-element file-shadowbox-sidebar" title="Pet scans of brain activity" typeof="foaf:Image" src="https://www.nih.gov/sites/default/files/news-events/research-matters/2018/20180510-alzheimers.jpg" width="1000" height="665" alt="Pet scans of brain activity" /></a><span class="caption">PET scans show the higher brain activity of a 50-year-old woman on a Mediterranean-style diet (left, image shows more red, which indicates higher activity) and a 50-year-old on a Western diet most of her life (right, image shows much less red). Arrows point to areas that are typically affected by Alzheimers disease, with lower activity for Western diet. </span><span class="credit">Weill Cornell Medicine</span></div>
</div></div>
<p>Alzheimers disease is the most common type of dementia that occurs with aging. Experts estimate that more than 5 million Americans are currently living with the disease. But scientists know little about what lifestyle factors might protect people against developing Alzheimers disease. They do know that brain changes associated with the disease can occur decades before symptoms are seen.</p>
<p>In previous work, a research team led by Dr. Lisa Mosconi from Weill Cornell Medicine found differences in brain imaging scans between people who reported eating a Mediterranean diet and those who ate a standard Western diet. A Mediterranean diet is high in foods such as fruits, vegetables, and lean protein. In contrast, a standard Western diet contains an excess of red meat, saturated fats, and refined sugar. The differences that the research team found may signal early Alzheimers disease.</p>
<p>In a new study, Mosconi and her colleagues measured changes in brains over time. They performed baseline brain imaging in 34 people who ate a Mediterranean diet and 36 people who ate a Western diet. The volunteers ranged in age from 30 to 60 and showed no symptoms of dementia when the study began. The researchers then repeated the scans at least two years later. The study was supported by NIHs National Institute on Aging (NIA). Results were published online in <em>Neurology</em> on April 13, 2018.</p>
<p>The brain scans taken at the beginning showed that the people who ate a Western diet already had more beta-amyloid deposits than those who ate a Mediterranean diet. Beta-amyloid is a protein known to collect in the brains of people with Alzheimers disease. The brains of those who ate a Western diet also showed lower energy use—a sign of brain activity—at the beginning of the study than those who ate a Mediterranean diet. Both these differences suggest the early development of dementia.</p>
<p>In the follow-up scans, people in the Western diet group showed even greater beta-amyloid deposits and reductions in energy use than the Mediterranean diet group. Factors such as age, sex, and a gene linked to Alzheimers risk didnt account for the differences.</p>
<p>“Were seeing these changes only in parts of the brain specifically affected by Alzheimers, and in relatively young adults,” Mosconi says. “It all points to the way we eat putting us at risk for Alzheimers down the line. If your diet isnt balanced, you really need to make an effort to fix it, if not for your body, then for your brain.”</p>
<p>The researchers estimate that there may be as much as a three-and-a-half-year delay in progression of Alzheimers disease in people who have eaten a Mediterranean diet for many years, rather than a standard Western diet. Research that involves larger and more diverse groups of people over longer periods of time is needed to confirm these findings. More work is also needed to understand exactly how a Mediterranean diet may protect people from harmful brain changes.</p>
<p>—by Sharon Reynolds</p></div><h2 class="label-above">Related Links</h2><ul class="spaced print-urls"><li><a href="https://www.nih.gov/news-events/nih-research-matters/compound-repairs-features-alzheimers-disease-mice" target="_top">Compound Repairs Features of Alzheimers Disease in Mice</a></li><li><a href="https://www.nih.gov/news-events/nih-research-matters/alzheimers-protein-may-have-natural-antibiotic-role" target="_top">Alzheimers Protein May Have Natural Antibiotic Role</a></li><li><a href="https://www.nih.gov/news-events/nih-research-matters/new-genes-tied-alzheimers-disease" target="_top">New Genes Tied to Alzheimers Disease</a></li><li><a href="https://newsinhealth.nih.gov/special-issues/seniors/dealing-dementia" target="_top">Dealing with Dementia</a></li><li><a href="https://www.nia.nih.gov/health/alzheimers-disease-fact-sheet" target="_top">Alzheimers Disease Fact Sheet</a></li><li><a href="https://www.nia.nih.gov/health/frequently-asked-questions-about-alzheimers-disease" target="_top">Frequently Asked Questions About Alzheimer's Disease</a></li></ul><p class="footnote"><strong class="label-inline">References:&nbsp;</strong><a href="https://www.ncbi.nlm.nih.gov/pubmed/29653991">Mediterranean diet and 3-year Alzheimer brain biomarker changes in middle-aged adults.</a> Berti V, Walters M, Sterling J, Quinn CG, Logue M, Andrews R, Matthews DC, Osorio RS, Pupi A, Vallabhajosula S, Isaacson RS, de Leon MJ, Mosconi L. <em>Neurology</em>. 2018 Apr 13. pii: 10.1212/WNL.0000000000005527. doi: 10.1212/WNL.0000000000005527. [Epub ahead of print] PMID: 29653991.</p><p class="footnote"><strong class="label-inline">Funding:&nbsp;</strong>NIHs National Institute on Aging; Weill Cornell Medical College Department of Neurology; and Alzheimers Prevention Clinic, Weill Cornell Memory Disorders Program.</p>
</div>
<div class="lastupdated">
</div> </div>
<aside class="l-region l-region--sidebar-second masonry-container">
<div id="block-ds-extras-in-this-edition" class="block block--ds-extras box block--ds-extras-in-this-edition" id="block-ds-extras-in-this-edition" class="block block--ds-extras box block--ds-extras-in-this-edition">
<h3 class="block__title">In this Edition</h3>
<div class="content" class="block__content">
<div class="view view-nih-rm-in-this-edition view-id-nih_rm_in_this_edition view-display-id-default view-dom-id-7c2570633b5280b123b613b781f1f095">
<div class="view-content">
<div>
<p><a href="/news-events/nih-research-matters/mediterranean-diet-may-slow-development-alzheimers-disease" class="active">Mediterranean diet may slow development of Alzheimers disease </a></p> </div>
<div>
<p><a href="/news-events/nih-research-matters/spinal-cord-stimulation-improves-hand-grip-after-cervical-spinal-injury">Spinal cord stimulation improves hand grip after cervical spinal injury</a></p> </div>
<div>
<p><a href="/news-events/nih-research-matters/butterfly-wing-inspires-design-glaucoma-sensor">Butterfly wing inspires design of glaucoma sensor </a></p> </div>
</div>
</div> </div>
</div>
<div id="block-bean-research-matters-search" class="block block--bean box block--bean-research-matters-search" id="block-bean-research-matters-search" class="block block--bean box block--bean-research-matters-search">
<h3 class="block__title">Search NIH Research Matters</h3>
<div class="content" class="block__content">
<div about="/block/research-matters---search" class="ds-1col entity entity-bean bean-research-matters-block view-mode-default clearfix">
<!-- DigitalGov Search -->
<form id="directorsearch" accept-charset="UTF-8" action="https://search.nih.gov/search/docs" method="get" class="search-form">
<div class="input-wrapper">
<div style="margin:0;padding:0;display:inline"><input name="utf8" type="hidden" value="✓" /></div>
<input id="affiliate" name="affiliate" type="hidden" value="nih" />
<input type="hidden" name="dc" value="678" />
<label for="query2" class="hide">Search NIH Research Matters' stories</label>
<input autocomplete="off" class="usagov-search-autocomplete form-field form-field-search" id="query2" name="query" type="text" />
<input name="commit" type="submit" value="Go" id="searchbutton" class="form-button" />
</div>
</form>
</div>
</div>
</div>
<div id="block-bean-research-matters-contact-us" class="block block--bean box block--bean-research-matters-contact-us" id="block-bean-research-matters-contact-us" class="block block--bean box block--bean-research-matters-contact-us">
<h3 class="block__title">Connect with Us</h3>
<div class="content" class="block__content">
<div about="/block/research-matters---contact-us" class="ds-1col entity entity-bean bean-research-matters-block view-mode-default clearfix">
<p><a class="button-link" href="https://service.govdelivery.com/accounts/USNIH/subscriber/new?topic_id=USNIH_48" onclick="window.open(this.href,'popup','width=725,height=500,left=25,top=25,location=no,resizable=yes,scrollbars=yes,status=yes');return false;">Subscribe to get NIH Research Matters by email</a></p>
<ul class="icon-list">
<li><a class="icon-link rss-monochrome" href="/nih-research-matters/feed.xml"><span class="icon"></span>RSS feed</a></li>
<li><a class="icon-link facebook-monochrome" href="https://www.facebook.com/ResearchMatters"><span class="icon"></span>Facebook</a></li>
<li><a class="icon-link email-monochrome" href="mailto:nihresearchmatters@od.nih.gov"><span class="icon"></span>Email us</a></li>
</ul>
<p><strong>Mailing Address:</strong><br />
NIH Research Matters<br />
Bldg. 31, Rm. 5B52, MSC 2094<br />
Bethesda, MD 20892-2094</p></div>
</div>
</div>
<div id="block-bean-research-matters-popular-stori" class="block block--bean box block--bean-research-matters-popular-stori" id="block-bean-research-matters-popular-stori" class="block block--bean box block--bean-research-matters-popular-stori">
<h3 class="block__title">Popular Stories</h3>
<div class="content" class="block__content">
<div about="/block/research-matters---popular-stori" class="ds-1col entity entity-bean bean-research-matters-block view-mode-default clearfix">
<p><a href="https://www.nih.gov/news-events/nih-research-matters/research-context-can-we-slow-aging">Research in Context: Can we slow aging?</a></p>
<p><a href="https://www.nih.gov/news-events/nih-research-matters/brain-changes-observed-during-pregnancy">Brain changes observed during pregnancy</a></p>
<p><a href="https://www.nih.gov/news-events/nih-research-matters/research-context-detecting-cancer">Research in Context: Detecting cancer</a></p>
<p><a href="https://www.nih.gov/news-events/nih-research-matters/risk-future-burden-dementia-united-states">Risk and future burden of dementia in the United States </a></p>
<p><a href="https://www.nih.gov/news-events/nih-research-matters/complete-wiring-map-adult-fruit-fly-brain">Complete wiring map of an adult fruit fly brain</a></p>
</div>
</div>
</div>
<div id="block-bean-research-matters-about" class="block block--bean box block--bean-research-matters-about" id="block-bean-research-matters-about" class="block block--bean box block--bean-research-matters-about">
<h3 class="block__title">About NIH Research Matters</h3>
<div class="content" class="block__content">
<div about="/block/research-matters---about" class="ds-1col entity entity-bean bean-research-matters-block view-mode-default clearfix">
<p><strong>Editor:</strong> Harrison Wein, Ph.D.</p>
<p><strong>Assistant Editors:</strong> Vicki Contie and Brian Doctrow, Ph.D.</p>
<p><strong><em>NIH Research Matters </em></strong>is a weekly update of NIH research highlights reviewed by NIHs experts. It's published by the <a href="/institutes-nih/nih-office-director/office-communications-public-liaison">Office of Communications and Public Liaison</a> in the <a href="/institutes-nih/nih-office-director">NIH Office of the Director</a>.</p>
<p>ISSN 2375-9593</p>
</div>
</div>
</div>
</aside>
</div>
<div class="l-connect-wrapper">
<div class="l-connect">
<h2 class="element-invisible">Connect with Us</h2>
<ul>
<li><a class="contactus-monochrome" href="/about-nih/contact-us"><span class="icon"></span>Contact Us</a></li>
<li><a class="twitter-monochrome" href="https://twitter.com/NIH"><span class="icon"></span>X</a></li>
<li><a class="facebook-monochrome" href="https://www.facebook.com/nih.gov"><span class="icon"></span>Facebook</a></li>
<li><a class="instagram-monochrome" href="https://www.instagram.com/nihgov/"><span class="icon"></span>Instagram</a></li>
<li><a class="youtube-monochrome" href="https://www.youtube.com/user/nihod"><span class="icon"></span>YouTube</a></li>
<li><a class="flickr-monochrome" href="https://www.flickr.com/photos/nihgov/"><span class="icon"></span>Flickr</a></li>
<li><a class="social-monochrome" href="/news-events/social-media-outreach"><span class="icon"></span>More Social Media from NIH</a></li>
</ul>
</div>
</div>
</div>
</div>
<div class="l-footer-wrapper">
<footer class="l-footer" role="contentinfo">
<h2 class="element-invisible">Footer</h2>
<ul>
<li><a href="/">NIH Home</a></li>
<li><a href="/virtual-tour">Virtual Tour</a></li>
<li><a href="https://salud.nih.gov">En Español</a></li>
<li><a href="/about-nih/visitor-information">Visitor Information</a></li>
<li><a href="/about-nih/frequently-asked-questions">Frequently Asked Questions</a></li>
<li><a href="/privacy-policy">Privacy Policy</a></li>
<li><a href="/disclaimers">Disclaimers</a></li>
<li><a href="/accessibility">Accessibility</a></li>
<li><a href="/nih-website-archives">NIH Website Archives</a></li>
</ul>
<ul>
<li><a href="/nondiscrimination-notice">Nondiscrimination Notice</a></li>
<li><a href="/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office">Freedom of Information Act</a></li>
<li><a href="https://www.edi.nih.gov/no-fear-act">No Fear Act</a></li>
<li><a href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html">HHS Vulnerability Disclosure</a></li>
<li><a href="https://oig.hhs.gov">Office of Inspector General</a></li>
<li><a class="lastTab" href="https://www.usa.gov/">USA.gov</a></li>
</ul>
<p>NIH&hellip;Turning Discovery Into Health<sup>&reg;</sup></p>
<p>National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892</p>
<p><a href="https://www.hhs.gov">U.S. Department of Health and Human Services</a></p>
</footer>
</div>
<div class="back-to-top"><a href="#"><span class="icon-arrow-up"></span><span class="text">Back to Top</span></a></div>
</div>
</div>
<script src="https://www.nih.gov/sites/default/files/js/js_7Ukqb3ierdBEL0eowfOKzTkNu-Le97OPm-UqTS5NENU.js"></script>
<script src="https://www.nih.gov/sites/default/files/js/js_E9yUYWK8EMydR0HMIp2PahVxPAClXyH0Cnh782A15UM.js"></script>
</body>
</html>