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<p class="pretitle"><a href="/about-nih/what-we-do/impact-nih-research/revolutionizing-science">Revolutionizing Science</a></p><div class='syndicate'><h1>Resource Sharing</h1><div><p>NIH spearheads the sharing of resources across the research enterprise to advance science in ways that were not previously possible.</p>
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<h3>Genomic Data Sharing</h3>
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<p></p><div class="media media-element-container media-feature_teaser"><div id="file-73346" class="file file-image file-image-jpeg">
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<!--[if IE 9]><video style="display: none;"><![endif]-->
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--genetic-data-sharing.jpg?itok=I1yOLcbd&timestamp=1675181214 1x" media="screen and (min-width: 800px)"></source>
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/about-nih/impact/resource-sharing--genetic-data-sharing.jpg?itok=rOSOrQ-e&timestamp=1675181214 1x" media="screen and (min-width: 600px)"></source>
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/about-nih/impact/resource-sharing--genetic-data-sharing.jpg?itok=ZwS4DENj&timestamp=1675181214 1x" media="screen and (min-width: 480px)"></source>
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/about-nih/impact/resource-sharing--genetic-data-sharing.jpg?itok=NwcQpTvd&timestamp=1675181214 1x" media="screen and (min-width: 0)"></source>
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<!--[if IE 9]></video><![endif]-->
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<img class="media-element" src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--genetic-data-sharing.jpg?itok=I1yOLcbd&timestamp=1675181214" alt="Illustration of the hierarchical ontology of genes, cellular components and processes derived from large genomic datasets." title="Genomic Data Sharing" />
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<p>Data and resources shared by NIH significantly bolstered the research community’s ability to investigate the effects of gene behavior on complex diseases. This widespread sharing of information led to new insights into type 1 diabetes, coronary artery disease, bipolar disorder, and schizophrenia, among others.</p>
|
||
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<p class="credit">Image credit: Janusz Dutkowski and Trey Ideker, University of California, San Diego</p>
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<li>Variations in genes can affect the way that genes behave in health and disease.</li>
|
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<li>In 2014, NIH released the Genomic Data Sharing Policy, which set forth expectations and facilitated the sharing of genomic research data broadly and responsibly.</li>
|
||
<li>The NIH Common Fund Genotype-Tissue Expression Project created a catalog of genetic variants that includes over 17,000 RNA-sequencing samples from 948 donors, and a related online resource stores and shares data that has been used to support over 7,000 publications, an example of how genomic data can be more impactful when it is shared.</li>
|
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<h3>Instrument Sharing</h3>
|
||
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<p></p><div class="media media-element-container media-feature_teaser"><div id="file-73356" class="file file-image file-image-jpeg">
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--instrument-sharing.jpg?itok=BPj51KQo&timestamp=1675181321 1x" media="screen and (min-width: 800px)"></source>
|
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/about-nih/impact/resource-sharing--instrument-sharing.jpg?itok=Y7Px2pgI&timestamp=1675181321 1x" media="screen and (min-width: 600px)"></source>
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/about-nih/impact/resource-sharing--instrument-sharing.jpg?itok=MeRNXZbA&timestamp=1675181321 1x" media="screen and (min-width: 480px)"></source>
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/about-nih/impact/resource-sharing--instrument-sharing.jpg?itok=o-_WDPeY&timestamp=1675181321 1x" media="screen and (min-width: 0)"></source>
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<!--[if IE 9]></video><![endif]-->
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<img class="media-element" src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--instrument-sharing.jpg?itok=BPj51KQo&timestamp=1675181321" alt="Researchers looking at images of mouse muscle fibers on the confocal microscope's projection screen." title="Instrument Sharing" />
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<p>NIH accelerates scientific discovery through supporting the purchase of state-of-the-art commercially available instruments that are too expensive to be acquired by an individual researcher. These instruments are used on a shared basis across institutions, enabling them to be used by multiple researchers and projects.</p>
|
||
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<p class="credit">Image credit: Rhoda Baer, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH</p>
|
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<li>Shared resources are cost-efficient and beneficial to thousands of researchers in hundreds of institutions nationwide.</li>
|
||
<li>Since 2012, NIH funded the purchase of over 1,100 scientific instruments, which advanced and enabled new NIH-funded research. </li>
|
||
<li>Over 11,000 research publications have cited the use of NIH-supported instruments. Through this program, biomedical researchers gained access to modern scientific instruments that they would not otherwise have been able to use due to the exceedingly high cost of purchasing advanced scientific equipment.</li>
|
||
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<h3>Behavioral Science</h3>
|
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<!--[if IE 9]><video style="display: none;"><![endif]-->
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--behavioral-science.jpg?itok=-6PyXWog&timestamp=1675181214 1x" media="screen and (min-width: 800px)"></source>
|
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/about-nih/impact/resource-sharing--behavioral-science.jpg?itok=x4MsBvwv&timestamp=1675181214 1x" media="screen and (min-width: 600px)"></source>
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/about-nih/impact/resource-sharing--behavioral-science.jpg?itok=BBWOgmky&timestamp=1675181214 1x" media="screen and (min-width: 480px)"></source>
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<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/about-nih/impact/resource-sharing--behavioral-science.jpg?itok=2HNALDXP&timestamp=1675181214 1x" media="screen and (min-width: 0)"></source>
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<!--[if IE 9]></video><![endif]-->
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<img class="media-element" src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--behavioral-science.jpg?itok=-6PyXWog&timestamp=1675181214" alt="A scientist holds up a tank of zebrafish to observe their behavior." title="Behavioral Science" />
|
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</picture> </div>
|
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|
||
<p>NIH-funded research improved our understanding of human behavior and transformed how human behavioral research is conducted. For example, NIH supports a collection of more than 250 behavioral science measures, targets, and experimental outcomes in a publicly accessible repository.</p>
|
||
|
||
<p class="credit">Image credit: Ernesto del Aguila III, National Human Genome Research Institute, NIH</p>
|
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<li>The NIH Common Fund Science of Behavior Change Program demonstrated how interventions focused on behavioral change, such as adherence to medical regimens, can influence health behaviors and be measured at the psychological, behavioral, social, and biological levels.</li>
|
||
<li>Human behavioral interventions are relevant to many disease conditions, such as disrupted sleep, type 2 diabetes, dementia, and chronic pain.</li>
|
||
</ul>
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</div>
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<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Back</a></div>
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<h3>Stem Cells</h3>
|
||
|
||
<p></p><div class="media media-element-container media-feature_teaser"><div id="file-73366" class="file file-image file-image-jpeg">
|
||
|
||
<h2 class="element-invisible"><a href="/impact/resource-sharing-stem-cells.jpg">resource-sharing--stem-cells.jpg</a></h2>
|
||
|
||
|
||
<div class="content">
|
||
<picture title="Stem Cells" class="media-element">
|
||
<!--[if IE 9]><video style="display: none;"><![endif]-->
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--stem-cells.jpg?itok=gVMBLq_0&timestamp=1675181321 1x" media="screen and (min-width: 800px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/about-nih/impact/resource-sharing--stem-cells.jpg?itok=E7X0IsQw&timestamp=1675181321 1x" media="screen and (min-width: 600px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/about-nih/impact/resource-sharing--stem-cells.jpg?itok=Fnee5Cmv&timestamp=1675181321 1x" media="screen and (min-width: 480px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/about-nih/impact/resource-sharing--stem-cells.jpg?itok=mmkA8m44&timestamp=1675181321 1x" media="screen and (min-width: 0)"></source>
|
||
<!--[if IE 9]></video><![endif]-->
|
||
<img class="media-element" src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--stem-cells.jpg?itok=gVMBLq_0&timestamp=1675181321" alt="A circular cluster of cells colored in red, green, and blue to indicate specific proteins and cell components." title="Stem Cells" />
|
||
</picture> </div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<p>NIH-supported science enabled the first U.S. clinical trial of patient-derived stem cell therapy to treat age-related macular degeneration. By developing scientific resources that could be shared with the broader scientific community, NIH accelerated the development of stem cell-based therapies that are potential tools for regenerative medicine.</p>
|
||
|
||
<p class="credit">Image credit: National Eye Institute, NIH</p>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Flip</a></div>
|
||
</div>
|
||
|
||
<div class="flipcard-back">
|
||
<div class="flipcard-content">
|
||
<ul class="spaced">
|
||
<li>The clinical trial used a type of patient-derived stem cell called induced pluripotent stem cells (iPSCs), which are adult cells reprogrammed to behave like embryonic stem cells—a type of stem cell that can become any cell in the body. </li>
|
||
<li>NIH developed and made available several iPSC cell lines for research and clinical use.</li>
|
||
<li>Other research groups are now using this protocol to develop therapeutics and working to overcome technical hurdles that will enable these cells to be used beyond research, such as in regular clinical practice.</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Back</a></div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="box flipcard">
|
||
<div class="flipcard-front">
|
||
<div class="flipcard-content">
|
||
<h3>Cancer Statistics</h3>
|
||
|
||
<p></p><div class="media media-element-container media-feature_teaser"><div id="file-73336" class="file file-image file-image-jpeg">
|
||
|
||
<h2 class="element-invisible"><a href="/impact/resource-sharing-cancer-statistics.jpg">resource-sharing--cancer-statistics.jpg</a></h2>
|
||
|
||
|
||
<div class="content">
|
||
<picture title="Cancer Statistics" class="media-element">
|
||
<!--[if IE 9]><video style="display: none;"><![endif]-->
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--cancer-statistics.jpg?itok=7nvr0V_5&timestamp=1675181214 1x" media="screen and (min-width: 800px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/about-nih/impact/resource-sharing--cancer-statistics.jpg?itok=tCYLMNVd&timestamp=1675181214 1x" media="screen and (min-width: 600px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/about-nih/impact/resource-sharing--cancer-statistics.jpg?itok=b2qczdya&timestamp=1675181214 1x" media="screen and (min-width: 480px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/about-nih/impact/resource-sharing--cancer-statistics.jpg?itok=xxlC0rMv&timestamp=1675181214 1x" media="screen and (min-width: 0)"></source>
|
||
<!--[if IE 9]></video><![endif]-->
|
||
<img class="media-element" src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--cancer-statistics.jpg?itok=7nvr0V_5&timestamp=1675181214" alt="Illustration of a human head and neck, with a rainbow of colored sticks emanating from a star image in the center of the head and radiating out to various pink- and purple-colored globes depicting viruses associated with head and neck cancers." title="Cancer Statistics" />
|
||
</picture> </div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<p>NIH and CDC fund the nation’s premiere resource for cancer statistics, the Surveillance, Epidemiology, and End Results (SEER) program. SEER collects data from multiple cancer registries—covering ~48% of the U.S. population—which can support an enormous variety of research studies and be used to inform nonprofit, state, and federal reports and policy changes.</p>
|
||
|
||
<p class="credit">Image credit: Ernesto del Aguila III, National Human Genome Research Institute, NIH</p>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Flip</a></div>
|
||
</div>
|
||
|
||
<div class="flipcard-back">
|
||
<div class="flipcard-content">
|
||
<ul class="spaced">
|
||
<li>SEER data are used to measure progress against cancer and identify challenges that need to be addressed. </li>
|
||
<li>SEER has also been linked to the Medicare database, creating a valuable source of detailed information on Medicare recipients with cancer.</li>
|
||
<li>SEER data have been used as the primary dataset in >17,000 publications and have been referenced in >86,000 publications.</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Back</a></div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="box flipcard">
|
||
<div class="flipcard-front">
|
||
<div class="flipcard-content">
|
||
<h3>Genomic Data</h3>
|
||
|
||
<p></p><div class="media media-element-container media-feature_teaser"><div id="file-73351" class="file file-image file-image-jpeg">
|
||
|
||
<h2 class="element-invisible"><a href="/impact/resource-sharing-genomic-data.jpg">resource-sharing--genomic-data.jpg</a></h2>
|
||
|
||
|
||
<div class="content">
|
||
<picture title="Genomic Data" class="media-element">
|
||
<!--[if IE 9]><video style="display: none;"><![endif]-->
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--genomic-data.jpg?itok=5ghQcPRF&timestamp=1675181321 1x" media="screen and (min-width: 800px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/about-nih/impact/resource-sharing--genomic-data.jpg?itok=QW7z6VIx&timestamp=1675181321 1x" media="screen and (min-width: 600px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/about-nih/impact/resource-sharing--genomic-data.jpg?itok=aoAEkarF&timestamp=1675181321 1x" media="screen and (min-width: 480px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/about-nih/impact/resource-sharing--genomic-data.jpg?itok=mbN09QGn&timestamp=1675181321 1x" media="screen and (min-width: 0)"></source>
|
||
<!--[if IE 9]></video><![endif]-->
|
||
<img class="media-element" src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--genomic-data.jpg?itok=5ghQcPRF&timestamp=1675181321" alt="Illustration of DNA double helix plugging into data servers to convey genomic data." title="Genomic Data" />
|
||
</picture> </div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<p>The NIH-funded Genomic Data Commons (GDC) enables researchers to share data in a way that allows the data to be reused and compared across different projects. This fosters a culture of collaboration and makes it much easier for researchers to access high-quality datasets for their research.</p>
|
||
|
||
<p class="credit">Image credit: Ernesto del Aguila III, National Human Genome Research Institute, NIH</p>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Flip</a></div>
|
||
</div>
|
||
|
||
<div class="flipcard-back">
|
||
<div class="flipcard-content">
|
||
<ul class="spaced">
|
||
<li>The GDC contains data from multiple cancer genomic datasets, including the Cancer Genome Atlas (TGCA) and the Therapeutically Applicable Research to Generate Effective Therapies (TARGET) database. </li>
|
||
<li>The GDC currently contains 2.9 petabytes (1 petabyte = 500 billion pages of standard printed text!) of primary sequencing data from over 60 projects. Since its inception in 2016, the GDC has been cited in over 400 publications.</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Back</a></div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="box flipcard">
|
||
<div class="flipcard-front">
|
||
<div class="flipcard-content">
|
||
<h3>ClinicalTrials.Gov</h3>
|
||
|
||
<p></p><div class="media media-element-container media-feature_teaser"><div id="file-73341" class="file file-image file-image-jpeg">
|
||
|
||
<h2 class="element-invisible"><a href="/impact/resource-sharing-clinicaltrials-gov.jpg">resource-sharing--clinicaltrials-gov.jpg</a></h2>
|
||
|
||
|
||
<div class="content">
|
||
<picture title="ClinicalTrials.gov" class="media-element">
|
||
<!--[if IE 9]><video style="display: none;"><![endif]-->
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--clinicaltrials-gov.jpg?itok=gva6w_8E&timestamp=1675181214 1x" media="screen and (min-width: 800px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/about-nih/impact/resource-sharing--clinicaltrials-gov.jpg?itok=kOohTmTh&timestamp=1675181214 1x" media="screen and (min-width: 600px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/about-nih/impact/resource-sharing--clinicaltrials-gov.jpg?itok=D2cyNBOB&timestamp=1675181214 1x" media="screen and (min-width: 480px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/about-nih/impact/resource-sharing--clinicaltrials-gov.jpg?itok=tBtZeIon&timestamp=1675181214 1x" media="screen and (min-width: 0)"></source>
|
||
<!--[if IE 9]></video><![endif]-->
|
||
<img class="media-element" src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--clinicaltrials-gov.jpg?itok=gva6w_8E&timestamp=1675181214" alt="Child is reading a book with one eye covered as part of clinical trial." title="ClinicalTrials.gov" />
|
||
</picture> </div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<p>Since 2000, the NIH-supported website, ClinicalTrials.gov, has provided easy access to information about nearly 400,000 publicly and privately supported clinical studies on a range of diseases and conditions in all 50 states and 220 countries. This resource is available to patients, their family members, health care professionals, and researchers.</p>
|
||
|
||
<p class="credit">Image credit: National Eye Institute, NIH</p>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Flip</a></div>
|
||
</div>
|
||
|
||
<div class="flipcard-back">
|
||
<div class="flipcard-content">
|
||
<ul class="spaced">
|
||
<li>NIH worked with FDA to develop the ClinicalTrials.gov website, which launched in 2000.</li>
|
||
<li>Anyone can use ClinicalTrials.gov to find a study for themselves or someone else, see results of completed studies, and learn how clinical research works. Researchers can also use the site to share up-to-date information about their clinical research. </li>
|
||
<li>ClinicalTrials.gov has information on nearly 400,000 registered studies, and in the past 12 months, the site has had 51 million unique visitors and 252 million page views.</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Back</a></div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="box flipcard">
|
||
<div class="flipcard-front">
|
||
<div class="flipcard-content">
|
||
<h3>PubMed</h3>
|
||
|
||
<p></p><div class="media media-element-container media-feature_teaser"><div id="file-73361" class="file file-image file-image-jpeg">
|
||
|
||
<h2 class="element-invisible"><a href="/impact/resource-sharing-pubmed.jpg">resource-sharing--pubmed.jpg</a></h2>
|
||
|
||
|
||
<div class="content">
|
||
<picture title="PubMed" class="media-element">
|
||
<!--[if IE 9]><video style="display: none;"><![endif]-->
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--pubmed.jpg?itok=3NI1Irnz&timestamp=1675181321 1x" media="screen and (min-width: 800px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/about-nih/impact/resource-sharing--pubmed.jpg?itok=42R1kxZ3&timestamp=1675181321 1x" media="screen and (min-width: 600px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/about-nih/impact/resource-sharing--pubmed.jpg?itok=XP855rbS&timestamp=1675181321 1x" media="screen and (min-width: 480px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/about-nih/impact/resource-sharing--pubmed.jpg?itok=hhf6RlMm&timestamp=1675181321 1x" media="screen and (min-width: 0)"></source>
|
||
<!--[if IE 9]></video><![endif]-->
|
||
<img class="media-element" src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--pubmed.jpg?itok=3NI1Irnz&timestamp=1675181321" alt="Illustration of the globe encircled by DNA sequences to convey worldwide sharing of genomic data." title="PubMed" />
|
||
</picture> </div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<p>Available online since 1996, PubMed is a free NIH-supported resource that facilitates the search and retrieval of biomedical and life sciences literature. The PubMed database contains more than 33 million citations and abstracts.</p>
|
||
|
||
<p class="credit">Image credit: Darryl Leja, NHGRI</p>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Flip</a></div>
|
||
</div>
|
||
|
||
<div class="flipcard-back">
|
||
<div class="flipcard-content">
|
||
<ul class="spaced">
|
||
<li>PubMed is the most frequently used scientific and medical literature database in the world.</li>
|
||
<li>PubMed has more than 2.5 billion daily searches by researchers, medical practitioners, and the public.</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Back</a></div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="box flipcard">
|
||
<div class="flipcard-front">
|
||
<div class="flipcard-content">
|
||
<h3>Research Facilities</h3>
|
||
|
||
<p></p><div class="media media-element-container media-feature_teaser"><div id="file-84231" class="file file-image file-image-jpeg">
|
||
|
||
<h2 class="element-invisible"><a href="/impact/resource-sharing-research-facilities.jpg">resource-sharing--research-facilities.jpg</a></h2>
|
||
|
||
|
||
<div class="content">
|
||
<picture title="Research Facilities" class="media-element">
|
||
<!--[if IE 9]><video style="display: none;"><![endif]-->
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--research-facilities.jpg?itok=MllxBA7S&timestamp=1735658355 1x" media="screen and (min-width: 800px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/about-nih/impact/resource-sharing--research-facilities.jpg?itok=ew1vT1IA&timestamp=1735658355 1x" media="screen and (min-width: 600px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/about-nih/impact/resource-sharing--research-facilities.jpg?itok=jBqPWgrt&timestamp=1735658355 1x" media="screen and (min-width: 480px)"></source>
|
||
<source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/about-nih/impact/resource-sharing--research-facilities.jpg?itok=g8ctAEoY&timestamp=1735658355 1x" media="screen and (min-width: 0)"></source>
|
||
<!--[if IE 9]></video><![endif]-->
|
||
<img class="media-element" src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/about-nih/impact/resource-sharing--research-facilities.jpg?itok=MllxBA7S&timestamp=1735658355" alt="NYU Langone Health’s Science Building" title="Research Facilities" />
|
||
</picture> </div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<p>Between 2004–2024, NIH funded the construction, renovation, and modernization of more than 300 research facilities in 45 states, Washington, D.C., and Puerto Rico, advancing cutting-edge biomedical research in a broad array of scientific areas, including cancer and infectious diseases.</p>
|
||
|
||
<p class="credit">Image credit: NYU Langone</p>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Flip</a></div>
|
||
</div>
|
||
|
||
<div class="flipcard-back">
|
||
<div class="flipcard-content">
|
||
<ul class="spaced">
|
||
<li>
|
||
<p>To promote cutting-edge research, NIH invests in building and updating facilities so that the most up-to-date technology and equipment is available to researchers.</p>
|
||
</li>
|
||
<li>
|
||
<p>NIH invests in modern physical infrastructure to advance all areas of biomedical research, from basic research to clinical trials.</p>
|
||
</li>
|
||
<li>
|
||
<p>NIH also supports the restoration of research facilities following disasters such as Hurricanes Sandy, Harvey, Irma, and Maria.</p>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="flipcard-button-wrapper"><a class="button-link-5em gray-light flipcard-button" href="javascript:;">Back</a></div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<h2>References</h2>
|
||
|
||
<h3>Genomic Data Sharing</h3>
|
||
|
||
<ol>
|
||
<li>NIH Genomic Data Sharing Policy: <a href="https://sharing.nih.gov/genomic-data-sharing-policy">https://sharing.nih.gov/genomic-data-sharing-policy</a></li>
|
||
<li>Database of Genotypes and Phenotypes: <a href="https://www.ncbi.nlm.nih.gov/gap/">https://www.ncbi.nlm.nih.gov/gap/</a></li>
|
||
<li>Genotype-Tissue Expression Program: <a href="https://commonfund.nih.gov/Gtex">https://commonfund.nih.gov/Gtex</a></li>
|
||
<li>GTEx Portal: <a href="https://gtexportal.org/home/">https://gtexportal.org/home/</a></li>
|
||
<li>Genotype – Tissue Expression (GTEx) Project: <a href="https://www.genome.gov/Funded-Programs-Projects/Genotype-Tissue-Expression-Project">https://www.genome.gov/Funded-Programs-Projects/Genotype-Tissue-Expression-Project</a></li>
|
||
<li>Gamazon ER, et al. <em>Nat Genet</em>. 2015;47(9):1091-8. PMID: <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552594/">26258848</a>.</li>
|
||
<li>Fromer M, et al. <em>Nat Neurosci</em>. 2016;19(11):1442-1453. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/27668389/">27668389</a>.</li>
|
||
<li>Article: Gene Duplication: New Analysis Shows How Extra Copies Split the Work: <a href="https://directorsblog.nih.gov/2016/05/31/gene-duplication-new-analysis-shows-how-extra-copies-split-the-work/">https://directorsblog.nih.gov/2016/05/31/gene-duplication-new-analysis-shows-how-extra-copies-split-the-work/</a></li>
|
||
</ol>
|
||
|
||
<h3>Instrument Sharing</h3>
|
||
|
||
<ol>
|
||
<li>S10 Instrumentation Search Results in RePORTER: <a href="https://reporter.nih.gov/search/xI5Pmyns9UCZNT4kOtydkw/projects?shared=true">https://reporter.nih.gov/search/xI5Pmyns9UCZNT4kOtydkw/projects?shared=true</a></li>
|
||
<li>NIH S10 Instrumentation Programs: Awards: <a href="https://orip.nih.gov/construction-and-instruments/s10-instrumentation-programs/filterable-awards-table">https://orip.nih.gov/construction-and-instruments/s10-instrumentation-programs/filterable-awards-table</a></li>
|
||
</ol>
|
||
|
||
<h3>Behavioral Science</h3>
|
||
|
||
<ol>
|
||
<li>Science of Behavior Change: <a href="https://commonfund.nih.gov/behaviorchange">https://commonfund.nih.gov/behaviorchange</a></li>
|
||
<li>The Measures of the Science of Behavior Change: <a href="https://measures.scienceofbehaviorchange.org/" target="_blank">https://measures.scienceofbehaviorchange.org/(link is external)</a></li>
|
||
<li>NIH Science of Behavior Change: <a href="https://www.nia.nih.gov/research/dbsr/science-behavior-change-sobc">https://www.nia.nih.gov/research/dbsr/science-behavior-change-sobc</a></li>
|
||
<li>Science of Behavior Change Program Highlights: <a href="https://commonfund.nih.gov/behaviorchange/programhighlights">https://commonfund.nih.gov/behaviorchange/programhighlights</a></li>
|
||
<li>Special issue of <em>Health Psychology</em>: The Science of Behavior Change: Implementing the Experimental Medicine Approach: <a href="https://psycnet.apa.org/PsycARTICLES/journal/hea/39/9" target="_blank">https://psycnet.apa.org/PsycARTICLES/journal/hea/39/9</a></li>
|
||
<li>Special issue of Behavior Therapy: An Experimental Therapeutics Focus on Novel Mechanistic Targets in Cognitive Behavioral Therapies: <a href="https://www.sciencedirect.com/journal/behavior-therapy/vol/54/issue/4">https://www.sciencedirect.com/journal/behavior-therapy/vol/54/issue/4</a></li>
|
||
<li>Checklist for Investigating Mechanisms in Behavioral Research: <a href="https://scienceofbehaviorchange.org/climbr-tool/">https://scienceofbehaviorchange.org/climbr-tool/</a></li>
|
||
</ol>
|
||
|
||
<h3>Stem Cells</h3>
|
||
|
||
<ol>
|
||
<li>Regenerative Medicine Program: <a href="https://commonfund.nih.gov/stemcells">https://commonfund.nih.gov/stemcells</a></li>
|
||
<li>Sharma R, et al. <em>Sci Transl Med</em>. 2019;11(475):eaat5580. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/30651323/">30651323</a>.</li>
|
||
<li>Article: NIH launches first U.S. clinical trial of patient-derived stem cell therapy to replace dying cells in retina: <a href="https://www.nih.gov/news-events/news-releases/nih-launches-first-us-clinical-trial-patient-derived-stem-cell-therapy-replace-dying-cells-retina">https://www.nih.gov/news-events/news-releases/nih-launches-first-us-clinical-trial-patient-derived-stem-cell-therapy-replace-dying-cells-retina</a></li>
|
||
<li>Article: NIH researchers rescue photoreceptors, prevent blindness in animal models of retinal degeneration: <a href="https://www.nih.gov/news-events/news-releases/nih-researchers-rescue-photoreceptors-prevent-blindness-animal-models-retinal-degeneration">https://www.nih.gov/news-events/news-releases/nih-researchers-rescue-photoreceptors-prevent-blindness-animal-models-retinal-degeneration</a></li>
|
||
<li>Stem Cell Translation Laboratory: <a href="https://ncats.nih.gov/stemcell">https://ncats.nih.gov/stemcell</a></li>
|
||
<li>AMD Integrative Biology Initiative: <a href="https://www.nei.nih.gov/about/goals-and-accomplishments/nei-research-initiatives/regenerative-medicine/amd-integrative-biology-initiative">https://www.nei.nih.gov/about/goals-and-accomplishments/nei-research-initiatives/regenerative-medicine/amd-integrative-biology-initiative</a></li>
|
||
</ol>
|
||
|
||
<h3>Cancer Statistics</h3>
|
||
|
||
<ol>
|
||
<li>Surveillance, Epidemiology and End Results (SEER) Program Metrics: <a href="https://seer.cancer.gov/about/factsheets/metrics.pdf">https://seer.cancer.gov/about/factsheets/metrics.pdf</a></li>
|
||
</ol>
|
||
|
||
<h3>Genomic Data</h3>
|
||
|
||
<ol>
|
||
<li>Heath AP, et al. <em>Nat Genet</em>. 2021;53(3):257-262. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/33619384/">33619384</a>.</li>
|
||
<li>Grossman RL, et al. <em>N Engl J Med</em>. 2016;375(12):1109-12. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/27653561/">27653561</a>.</li>
|
||
</ol>
|
||
|
||
<h3>ClinicalTrials.Gov</h3>
|
||
|
||
<ol>
|
||
<li>ClinicalTrials.gov: <a href="https://clinicaltrials.gov/">https://clinicaltrials.gov/</a></li>
|
||
</ol>
|
||
|
||
<h3>PubMed</h3>
|
||
|
||
<ol>
|
||
<li>PubMed Database: <a href="https://pubmed.ncbi.nlm.nih.gov/">https://pubmed.ncbi.nlm.nih.gov/</a></li>
|
||
</ol>
|
||
|
||
<h3>Research Facilities</h3>
|
||
|
||
<ol>
|
||
<li>ORIP Research Highlights: <a href="https://orip.nih.gov/about-orip/research-highlights">https://orip.nih.gov/about-orip/research-highlights</a></li>
|
||
<li>ORIP Extramural Construction Program: <a href="https://orip.nih.gov/division-construction-instruments/extramural-construction-programs">https://orip.nih.gov/division-construction-instruments/extramural-construction-programs</a></li>
|
||
<li>Article: NIH Partnered in Rebuilding and Transforming NYU Research Facilities From Aftermath of Superstorm Sandy: <a href="https://orip.nih.gov/about-orip/research-highlights/nih-partnered-rebuilding-and-transforming-nyu-research-facilities">https://orip.nih.gov/about-orip/research-highlights/nih-partnered-rebuilding-and-transforming-nyu-research-facilities</a></li>
|
||
</ol>
|
||
</div></div>
|
||
|
||
</div>
|
||
|
||
<div class="lastupdated">
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<p>This page last reviewed on December 31, 2024</p> </div> </div>
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