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<h1 itemprop="name">Ancillary Studies to Major Ongoing Clinical Studies</h1>
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<div >
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<p style="background: white;">NIDDK invites investigator-initiated (R01) research project applications for ancillary studies to ongoing large-scale clinical trials and epidemiological studies (parent studies) and disease databases supported by the Institute, other Institutes and Centers of the National Institutes of Health, other government agencies, or the private sector. Applications for ancillary studies may be submitted to <a href="https://grants.nih.gov/grants/guide/pa-files/pa-20-185.html">PA-20-185</a> or other appropriate notices of funding opportunities (NOFOs).</p>
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<p style="background: white;">Ancillary study proposals</p>
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<ul>
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<li style="background: white;">must extend knowledge of diseases being studied by parent study investigators under a defined protocol or study diseases and conditions outside of the original scope of the parent study but within the <a href="/research-funding/research-programs">research areas</a> and <a href="/about-niddk/meet-director/mission-vision">mission</a> of NIDDK</li>
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<li style="background: white;">must abide by the procedures for conducting ancillary studies established by the parent study</li>
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<li style="background: white;">may require additional data or sample collection</li>
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<li style="background: white;">may not interfere with the primary objectives of the parent study</li>
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</ul>
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<h2>Parent Study Examples</h2>
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<p style="background: white;">Select NIDDK-sponsored parent studies that are eligible for ancillary study proposals are listed below. View each website for study-specific ancillary study procedures.<span style="color: #575757;"> </span></p>
|
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<h3 id="demstudies">Diabetes Studies</h3>
|
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<ul>
|
||
<li><a href="https://dppos.bsc.gwu.edu/">Diabetes Prevention Program Outcomes Study (DPPOS)</a></li>
|
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<li><a href="http://diabeticfootconsortium.org/">Diabetic Foot Consortium</a></li>
|
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<li><a href="https://edic.bsc.gwu.edu/">Epidemiology of Diabetes Interventions and Complications Study (EDIC)</a></li>
|
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<li><a href="https://teddy.epi.usf.edu/">Environmental Determinants of Diabetes in the Young (TEDDY)</a></li>
|
||
<li><a href="https://www.atypicaldiabetesnetwork.org">RADIANT (Rare and Atypical Diabetes Network)</a><br />
|
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</li>
|
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<li><a href="https://t1dapc.net/">Type 1 Diabetes and Acute Pancreatitis Consortium (T1DAPC)</a> </li>
|
||
<li><a href="https://www.trialnet.org/">Type 1 Diabetes TrialNet</a></li>
|
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</ul>
|
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<h3 id="ddnstudies">Digestive Disease and Nutrition Studies</h3>
|
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<ul>
|
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<li><a href="https://www.connecticutchildrens.org/research/center-clinical-research/">Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed with Crohn’s Disease (CAMEO)</a></li>
|
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<li><a href="https://childrennetwork.org/">Childhood Liver Diseases Research and Education Network (ChiLDREN)</a><br />
|
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</li>
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<li><a href="https://www.cpdpc-research-consortium.org">Consortium to Study Chronic Pancreatitis, Diabetes and Pancreatic Cancer (CPDPC)</a>
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</li>
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<li><a href="http://www.dilin.org/">Drug-Induced Liver Injury Network (DILIN)</a></li>
|
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<li><a href="https://jhuccs1.us/gpcrc/Default.asp">Gastroparesis Clinical Research Consortium (GpCRC)</a></li>
|
||
<li><a href="https://www.youtube.com/watch?v=Dkt2PHFoSqo">Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)</a></li>
|
||
<li><a href="https://imalt.org/">Improving Medication Adherence In Children Who Had A Liver Transplant (iMALT)</a> </li>
|
||
<li><a href="https://www.ibdgenetics.org/">Inflammatory Bowel Disease Genetic Consortium (IBDGC)</a><br />
|
||
</li>
|
||
<li><a href="https://iscconsortium.org/">Intestinal Stem Cell Consortium (ISCC)</a></li>
|
||
<li><a href="https://www.lcnstudy.org/">Liver Cirrhosis Network (LCN)</a></li>
|
||
<li><a href="https://jhuccs1.us/nash/">Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)</a></li>
|
||
<li><a href="https://www.pancreasdivisum.com/">Sphincterotomy for Acute Recurrent Pancreatitis (SHARP)</a><br />
|
||
</li>
|
||
<li><a href="https://www.barretts-survent.com/contact-us">SURVeillance vs. ENdoscopic Eradication Therapy Trial (SURVENT)</a> </li>
|
||
<li><a href="https://t1dapc.net/">Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC)</a> </li>
|
||
<li><a href="https://www.glutechtrial.org">Gluten Technology and Education for Celiac Healing (GLUTECH Trial)</a></li>
|
||
<li><a href="https://www.cceb.med.upenn.edu/crcu/announcements/urbi-study-randomized-trial-utility-random-biopsies-patients-inflammatory-bowel">A Randomized Trial of the Utility of Random Biopsies in Patients with Inflammatory Bowel Disease (URBI Study)</a></li>
|
||
</ul>
|
||
<h3 id="kuhstudies">Kidney, Urology and Hematology Studies</h3>
|
||
<ul>
|
||
<li><a href="https://theapollonetwork.org/index.cfm">ApoL1 Long-term Kidney Transplantation Outcomes Consortium (APOLLO)</a></li>
|
||
<li><a href="http://www.cristudy.org/Chronic-Kidney-Disease/Chronic-Renal-Insufficiency-Cohort-Study/">Chronic Renal Insufficiency Cohort (CRIC) Study</a></li>
|
||
<li><a href="https://statepi.jhsph.edu/ckid/">Chronic Kidney Disease in Children (CkiD) Study</a></li>
|
||
<li><a href="https://curegn.org/">Cure Glomerulonephropathy (CureGN)</a></li>
|
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<li><a href="https://www.kpmp.org/">Kidney Precision Medicine Project (KPMP)</a></li>
|
||
<li><a href="https://www.neptune-study.org/">Nephrotic Syndrome Study Network (NEPTUNE)</a></li>
|
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<li><a href="https://www.rarediseasesnetwork.org/cms/porphyrias">Porphyria Consortium</a><br />
|
||
</li>
|
||
<li><a href="https://plusconsortium.umn.edu/">Prevention of Lower Urinary Tract Symptoms (PLUS)</a><br />
|
||
</li>
|
||
<li><a href="https://nih-lurn.org/">Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)</a></li>
|
||
<li><a href="https://usdrn.org/">Urinary Stone Disease Research Network (USDRN)</a></li>
|
||
<li><a href="https://www.thinkernextstudy.org/">Transplanting Hepatitis C Kidneys Into Negative KidnEy Recipients (THINKER-NEXT)</a></li>
|
||
<li><a href="https://cope-akistudy.pitt.edu/">Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI)</a><br />
|
||
</li>
|
||
</ul>
|
||
<h3 id="obesitystudies">Obesity Studies</h3>
|
||
<ul>
|
||
<li><a href="https://www.powers-study.org/">Physiology of the Weight Reduced State (POWERS)</a></li>
|
||
</ul>
|
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</div>
|
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<div class="dk-review-date">Last Reviewed October 2024</div>
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