2209 lines
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|
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|
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<span class="staff-card--header--name"><a href="/about-nibib/staff/kari-ashmont" title="View Kari Ashmont's profile">Kari Ashmont</a>
|
||
, Ph.D.
|
||
<a href="mailto:kari.ashmont@nih.gov" title="Email Kari Ashmont" >
|
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<svg class="usa-icon" aria-hidden="true" focusable="false" role="img">
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<span>
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<div class="field field--name-field-staff-title field--type-entity-reference field--label-hidden field__item">Translational Team Lead</div>
|
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</span>
|
||
</div>
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</div>
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</div>
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</div></div>
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|
||
<h2>Purpose</h2>
|
||
<p>The C3i Program is designed to provide medical device innovators with the specialized business frameworks and essential tools for successful translation of biomedical technologies from the lab (concept) to the market (clinic). Through this program, the NIH fosters the development and commercialization of early-stage biomedical technologies by engaging investigators who are interested in better understanding the value of their innovation in addressing an unmet market need. The curriculum and customized mentoring provided by the C3i Program are intended to guide investigators as they assess the commercial viability and potential business opportunity for their innovation.</p>
|
||
<h2>Program description</h2>
|
||
<p>The C3i Program is a 24-week entrepreneurial training course, divided into two 12-week phases, and consists of one in-person event, weekly teleconferences, lectures, and coursework. Participants in the C3i Program will develop a comprehensive set of core skills that will enable them to:</p>
|
||
<ol>
|
||
<li>evaluate whether a compelling unmet market need exists for their proposed solution</li>
|
||
<li>assess whether there is a viable business opportunity that can be built to meet this need</li>
|
||
<li>build a compelling pitch presentation to secure support from potential investors and other business partners.</li>
|
||
</ol>
|
||
<p>The teams will be guided through a series of lectures and interactive exercises, pressure-testing commercial viability of ideas using universal business criteria as well as the unique requirements of medical device commercialization. Participants also work with experienced business advisors and subject matter experts who provide insights into the market sector, intellectual property, regulatory, and reimbursement requirements specific for their projects.</p>
|
||
<p>The first 12 weeks, Phase I of the course, will focus on characterizing the unmet market need, identifying the customer and stakeholder segments, conducting customer and stakeholder interviews, and validating the business opportunity. The second 12 weeks, Phase II of the course, will provide commercialization planning support, covering intellectual property strategy, regulatory and reimbursement requirements, risk assessment, milestone creation and valuation, and preparations for pitching to investors and/or strategic partners.</p>
|
||
<p>The C3i Program is being offered to investigators with active NIH-funded research grants from participating Institutes and Centers. All costs associated with participation in the program are covered with the exception of travel to and from the in-person events. </p>
|
||
<h2 dir="auto">Participating Institutes/Centers</h2>
|
||
<p>The following Institutes and Centers are currently participating in the C3i course. Prospective applicants are strongly encouraged to contact NIH Scientific/Research staff for more information about this program before submitting an application.</p>
|
||
<p><strong>National Institute on Aging (</strong><a href="https://www.nia.nih.gov/"><strong>NIA</strong></a><strong>)</strong><br>Rajesh Kumar<br>Telephone: 301-402-7785<br>Email: <a href="mailto:rajesh.kumar3@nih.gov">rajesh.kumar3@nih.gov</a></p>
|
||
<p><strong>National Institute of Biomedical Imaging and Bioengineering (</strong><a href="https://www.nibib.nih.gov/"><strong>NIBIB</strong></a><strong>)</strong><br>Kari Ashmont<br>Telephone: 301-451-4772<br>Email: <a href="mailto:NIBIB-SBIR@mail.nih.gov">NIBIB-SBIR@mail.nih.gov</a></p>
|
||
<p><strong>Eunice Kennedy Shriver National Institute of Child Health and Human Development (</strong><a href="https://www.nichd.nih.gov/"><strong>NICHD</strong></a><strong>)</strong><br>Toyin Ajisafe, Ph.D.<br>Telephone: 301-827-9242<br>Email: <a href="mailto:toyin.ajisafe@nih.gov">toyin.ajisafe@nih.gov</a></p>
|
||
<p><strong>National Institute of Diabetes and Digestive and Kidney Diseases (</strong><a href="https://www.niddk.nih.gov/"><strong>NIDDK</strong></a><strong>)</strong><br>Daniel Gossett, Ph.D.<br>Telephone: 301-569-0395<br>Email: <a href="mailto:daniel.gossett@nih.gov">daniel.gossett@nih.gov</a></p>
|
||
<p><strong>National Institute of General Medical Sciences (</strong><a href="https://www.nigms.nih.gov/"><strong>NIGMS</strong></a><strong>)</strong><br>Eddie Billingslea<br>Phone: 301-451-4317<br>Email: <a href="mailto:eddie.billingslea@nih.gov">eddie.billingslea@nih.gov</a></p>
|
||
<p><strong>National Institute of Mental Health (</strong><a href="https://www.nimh.nih.gov/index.shtml"><strong>NIMH</strong></a><strong>)</strong><br>Paige Anderson<br>Phone: 301-827-6550<br>Email: <a href="mailto:paige.anderson@nih.gov">paige.anderson@nih.gov</a></p>
|
||
<p><strong>National Institute of Neurological Disorders and Stroke (</strong><a href="https://www.ninds.nih.gov/"><strong>NINDS</strong></a><strong>)</strong><br>Emily Caporello<br>Telephone: 301-496-1779<br>Email: <a href="mailto:mily.caporello@nih.gov">emily.caporello@nih.gov</a></p>
|
||
<p><strong>National Heart, Lung, and Blood Institute (</strong><a href="https://www.nhlbi.nih.gov/"><strong>NHLBI</strong></a><strong>)</strong><br>Stephanie Davis<br>Telephone: 301-496-2149<br>Email: <a href="mailto:NHLBI_SBIR@mail.nih.gov">NHLBI_SBIR@mail.nih.gov</a></p>
|
||
<p><strong>National Institute of Nursing Research (</strong><a href="https://www.ninr.nih.gov/"><strong>NINR</strong></a><strong>)</strong><br>Kristopher Bough<br>Telephone: 301-337-1372<br>Email: <a href="mailto:kristopher.bough@nih.gov">kristopher.bough@nih.gov</a></p>
|
||
<p><strong>Brain Research through Advancing Innovative Neurotechnologies® (</strong><a href="https://braininitiative.nih.gov/"><strong>BRAIN</strong></a><strong>) Initiative</strong><br>For investigators with active BRAIN Initiative awards through NIMH, NIA, NIBIB and NINDS please contact the NIH Scientific/Research staff for that Institute (see above).</p>
|
||
<p><strong>For all other BRAIN Initiative investigators, please contact:</strong> <br>Jaclyn Durkin<br>Email: <a href="mailto:jaclyn.durkin@nih.gov" data-extlink>jaclyn.durkin@nih.gov</a> <br>Paige Anderson<br>Telephone: 301-827-6550<br>Email: <a href="mailto:paige.anderson@nih.gov" data-extlink>paige.anderson@nih.gov</a></p>
|
||
<h2>Eligibility</h2>
|
||
<p>The C3i Program is being offered to investigators with active NIH-funded research projects from participating Institutes and Centers. It is designed for medical device innovators who are interested in understanding whether they have a compelling commercialization opportunity and how they can package this opportunity to interest investors and/or business partners. Much of the course is dedicated to validating the basis for further investment of time, energy, and money by the Project Team and future business partners. Project Teams are pushed to question and challenge the fundamental assumptions and basis for the 'business hypothesis' they are trying to validate during the Program.</p>
|
||
<p>It is strongly recommended that Project Teams consist of at least two members: 1) Inventor or Technical Lead, and 2) Business Lead. The Inventor or Technical Lead has primary responsibility for achieving the technical success of the project. The Technical Lead should be the PD/PI for the parent award project, or a co-investigator, with in-depth knowledge of the technology or innovation. The Business Lead has primary responsibility for guiding the overall business development and commercialization strategy for the project. For existing companies, the Business Lead should be the Chief Executive Office (CEO) or other C-level officer (e.g. Chief Technology Officer or Chief Operating Officer). For academic teams, the Business Lead should be an individual with a deep commitment to investigate the commercial landscape surrounding the innovation and would be most likely to take on the role of CEO if a company were to be formed. In the scenario in which the Technical Lead (PD/PI) might also serve as the Business Lead (CEO) for the project, applicants are encouraged to consider identifying an additional Project Team member with considerable commitment to the project. Project Team members are not required to be key personnel on the parent award project.</p>
|
||
<p>While the C3i Program is designed for interactive learning and one-on-one coaching elements, there is a structure and cadence to the course such that consistent participation is required across the exercises and sessions, which build upon each other. Thus, the Program is only recommended for Participants who can commit the time and effort to actively and consistently participate in the Boot Camps and one-on-one coaching sessions (estimated 10-15 hours per week).</p>
|
||
<p>Eligible grant award mechanisms are listed below for each participating Institute and Center:</p>
|
||
<ul>
|
||
<li><strong>The National Institute of Aging (NIA) </strong>will support active grant awards from SBIR/STTR (R41, R42, R43, R44) activity codes.</li>
|
||
<li><strong>The National Institute of Biomedical Imaging and Bioengineering (NIBIB)</strong> will support active grant awards from SBIR/STTR (R41, R42, R43, R44) and research project (R00, R01, U01, P41) activity codes.</li>
|
||
<li><strong>The Eunice Kennedy Shriver National Institute of Child Health and Human Development (</strong><a href="https://www.nichd.nih.gov/"><strong>NICHD</strong></a><strong>)</strong> will support active grant awards from SBIR/STTR (R41, R42, R43, R44) and research project activity codes including K99/R00, R01, R61/R33, R15, R21, R25, U01, and P50. Applicants are encouraged to contact NICHD prior to submitting to ascertain eligibility and program alignment</li>
|
||
<li><strong>The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) </strong>will support active Phase I SBIR/STTR grant awards (including Phase I of a Fast-Track award) with the following activity codes R41, R42, R43, R44. <span style="color:#333333;font-family:"Arial",sans-serif;font-size:13.5pt;">The NIDDK will also support prior eC3i participants whose eC3i eligibility was based on a NIDDK R00, R01, R15, R21, R25, RC2, P01, P20, P50.</span><span><o:p></o:p></span></li>
|
||
<li><strong>The National Institute of General Medical Sciences (NIGMS) </strong>will support active SBIR/STTR awards (R41, R42, R43, R44) and active grant awards from the Technology Development R01 program.</li>
|
||
<li><strong>The National Institute of Mental Health (NIMH)</strong> will support active grant awards from SBIR/STTR (R41, R42, R43, R44) and research grants including R01 and U01 activity codes. Specifically, grantees developing devices focused on the Central Nervous System, Psychiatry or Autism, including those utilized as interventions, biomarkers, assessments/diagnostics and digital health technologies, would be considered eligible. Please contact Paige Anderson prior to submitting to ensure your award is eligible.</li>
|
||
<li><strong>The National Institute of Neurological Disorders and Stroke (NINDS)</strong> will support active grant awards from SBIR/STTR (R41, R42, R43, R44, U44) and research project (R01, R24, U01, U24, UG3/UH3, UH2/UH3) activity codes.</li>
|
||
<li><strong>The National Heart, Lung, and Blood Institute (NHLBI)</strong> will support active grant awards from SBIR/STTR (R41, R42, R43, R44) and research project (P01, P41, U54, R00, R01, R21, R24, R33, R61, U01, U44, UG3/UH3, UH2/UH3, R35, K01, K08, K23, K25, F31, F30, T32, R03, F32, K99, Contract Mechanisms) activity codes.</li>
|
||
<li><strong>National Institute of Nursing Research (NINR)</strong> will support active grant awards from SBIR/STTR (R41, R42, R43, R44) and research project (R01, R21) activity codes.</li>
|
||
<li><strong>Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative: </strong>active grant awards from BRAIN-funded SBIR/STTR (R41, R42, R43, R44), or research project (F32, F99/K00, K99/R00, R01, R24, R25, R34, R41, R42, R43, R44, RF1, U01, U19, U24, U44, UF1, UG3/UH3, UH2/UH3) activity codes. Prospective BRAIN applicants are strongly encouraged to contact their program officer for more information about this program before submitting an application.</li>
|
||
</ul>
|
||
<h2>Course Details</h2>
|
||
<p><strong>Boot Camp 1</strong></p>
|
||
<p>Project Teams kick-off their C3i Program experience with an intensive, 2-day virtual workshop. Through a series of lectures and interactive exercises, Project Teams are introduced to key concepts and tools they can use to validate the unmet need and the business opportunity. During the exercises, Project Teams receive mentoring from Business Advisors, as well as feedback from other participating Project Teams.</p>
|
||
<p><strong>Weekly One-on-Ones/Stakeholder Interviews</strong></p>
|
||
<p>Following the completion of Boot Camp 1, Project Teams meet weekly with their Business Advisors throughout the course. These weekly one-on-one meetings are held via web or teleconference. During this time, Project Teams delve into validating both the unmet need and business opportunity of their technology, identifying and learning from the key stakeholder groups and organizations that will influence the commercialization success of their product. Due to the complexity of the health care system, the analysis of key stakeholders and how they stand to benefit or lose from the adoption of new technology is critical to understanding the potential business opportunity and to informing the go-to-market strategy, if there is one.</p>
|
||
<p>In between each weekly session, Project Teams conduct interviews with key stakeholders and report back how the findings have helped inform or refine the commercialization landscape for their envisioned product. It is recommended that a Project Team speaks with at least 30 stakeholders to gather sufficient breadth of perspective. It is equally important that these interviews are held with various stakeholder groups, as applicable for the envisioned product (e.g. health care provider, referring providers, patients, health care payor, purchasing agent or other entities with direct buying authority, potential strategic partner, potential investor, etc.).</p>
|
||
<p><strong>Group Teleconferences</strong></p>
|
||
<p>Following several weeks of stakeholder interviews, groups of Project Teams meet via web conference to present what they have learned from their stakeholder interviews. The goal of these group meetings is to share progress, receive feedback and coaching, and learn from the entire Business Advisor group. Several group teleconferences are held throughout the course on topics relevant to the business model and final pitch preparation.</p>
|
||
<p><strong>Lectures</strong></p>
|
||
<p>There are a number of lectures given throughout the course, addressing specific topics related to medical device commercialization. These lectures average 30 minutes in length with additional time for questions and discussion directly following the lecture. Subject matter experts are recruited to deliver these lectures. Some of these lectures are given during the Boot Camps and some are given via web conference.</p>
|
||
<p><strong>Boot Camp 2</strong></p>
|
||
<p>Between Phase 1 and Phase 2 of the program, an <strong>in-person</strong> workshop will be held to further engage with Business Advisors and Project Managers and to network with other participating teams. Lectures and interactive activities will be focused on topics being covered in Phase 2 around commercialization planning support.</p>
|
||
<p><strong>Final Presentations</strong></p>
|
||
<p>The final event of the Program consists of a 1.5-day virtual workshop in which teams reconvene to deliver final pitch presentations focused on the value proposition and the investment opportunity. As they have throughout the Program, Business Advisors will be on hand to provide real-time feedback and guidance.</p>
|
||
<p><strong>Business Advisors and Project Managers</strong></p>
|
||
<p>C3i Business Advisors and Project Managers serve as a critical and knowledgeable resource with direct and extensive experience in biomedical technology commercialization, particularly working with early-stage innovators and small companies. The role of the Business Advisor and Project Manager is to: 1) enhance the Team's understanding of the biomedical technology commercialization process, 2) hone the Team's business case and investor pitch, and 3) increase the Team's chance of securing follow-on funding, through SBIR, VC, strategic partners, and other capital sources. Each Project Team is assigned 1 Business Advisor and 1 Project Manager with the assignments largely based on the closest match between the business experience of the Business Advisor and the product the Project Teams are seeking to commercialize (e.g. devices, diagnostics, imaging).</p>
|
||
<h2>Apply Now!</h2>
|
||
<p>Applications are now open! Click the application link below to access and submit the application.</p>
|
||
<p><a class="usa-button usa-button--unstyled" href="https://www.nibib.nih.gov/research-program/c3i-program/nih_c3i_application">Application Link</a></p>
|
||
<h2>Timeline</h2>
|
||
<ul>
|
||
<li><strong>Application Due Date:</strong> August 2, 2024</li>
|
||
<li><strong>Notice of Participation: </strong>August 23, 2024</li>
|
||
<li><strong>Program Dates:</strong>
|
||
<ul>
|
||
<li>Program Start: October 1, 2024</li>
|
||
<li>Mid-Course Boot Camp (in-person): February 25-27, 2025</li>
|
||
<li>Final Presentations (virtual): May 1-2, 2025</li>
|
||
</ul>
|
||
</li>
|
||
</ul>
|
||
<p><strong>Email</strong><a href="mailto:NIBIB-SBIR@mail.nih.gov"><strong>NIBIB-SBIR@mail.nih.gov</strong></a><strong> if you have any questions.</strong></p>
|
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