2133 lines
78 KiB
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2133 lines
78 KiB
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<meta name="description" content="The National Institutes of Health has awarded three new contracts totaling $36.7 million for the development of new COVID-19 diagnostic testing technologies and production of specimen collection kits and swabs. The Rapid Acceleration of Diagnostics (RADx) initiative has advanced the scale-up of 25 testing projects since July 2020, which now include lab-based, point-of-care, and potential at-home formats." />
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|
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<div class="desktop:grid-col-4 submenu-list-container">
|
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|
||
<div class="usa-nav__submenu-item">
|
||
<span class="nolink"> <span class="usa-nav__submenu-heading">EXPLORE and LEARN</span>
|
||
</span>
|
||
</div>
|
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|
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|
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|
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|
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|
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|
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|
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<ul id="basic-nav-section-3" class="usa-nav__submenu-list">
|
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|
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|
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<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/Understanding-Medical-Scans-App" target="_self" class="link" data-drupal-link-system-path="node/68546"> <span>Medical Imaging App</span>
|
||
</a>
|
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|
||
</li>
|
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|
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|
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|
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|
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<li class="usa-nav__submenu-item">
|
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|
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|
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|
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|
||
<a href="/science-education/beams-challenge" class="link" data-drupal-link-system-path="node/143486"> <span>Lesson Plans</span>
|
||
</a>
|
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|
||
</li>
|
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|
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|
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|
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<li class="usa-nav__submenu-item">
|
||
|
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|
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|
||
|
||
<a href="/science-education/meet-a-scientist" class="link" data-drupal-link-system-path="node/141721"> <span>Meet a Scientist</span>
|
||
</a>
|
||
|
||
</li>
|
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|
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|
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|
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<li class="usa-nav__submenu-item">
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<a href="https://www.youtube.com/playlist?list=PLYH1eUq1QYrqrvA6HRRgKHcPsoJoJA6Kj" target="_blank" class="link"> <span>Featured Videos</span>
|
||
</a>
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</li>
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<li class="usa-nav__submenu-item">
|
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|
||
<a href="/science-education/glossary" target="_self" class="link" data-drupal-link-system-path="science-education/glossary"> <span>Glossary</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
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|
||
|
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|
||
</div>
|
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|
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|
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</div>
|
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</div>
|
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<li class="usa-nav__primary-item">
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<button type="button" class="usa-accordion__button usa-nav__link " aria-expanded="false" aria-controls="extended-mega-nav-section-5">
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<span>News & Events </span>
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</button>
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<div id="extended-mega-nav-section-5" class="usa-nav__submenu usa-megamenu" hidden="">
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<div class="grid-row mm-container">
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<div class="desktop:grid-col flex-auto duplicated-parent">
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<div class="usa-nav__submenu-item">
|
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<span><a href="/news-events" target="_self" class="link" data-drupal-link-system-path="node/156671">News & Events</a> <span class="uswds-arrow-forward"></span></span>
|
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</div>
|
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</div>
|
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</div>
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<div class="usa-nav__submenu-item">
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<span target="_self" class="nolink"> <span class="usa-nav__submenu-heading">NEWS</span>
|
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</span>
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<ul id="basic-nav-section-1" class="usa-nav__submenu-list">
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<li class="usa-nav__submenu-item">
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|
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<a href="/news-events/newsroom" class="link" data-drupal-link-system-path="news-events/newsroom"> <span>Newsroom</span>
|
||
</a>
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|
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</li>
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<li class="usa-nav__submenu-item">
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<a href="/news-events/press-releases" target="_self" class="link" data-drupal-link-system-path="news-events/press-releases"> <span>Press Releases</span>
|
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</a>
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<li class="usa-nav__submenu-item">
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<a href="/news-events/science-highlights" target="_self" class="link" data-drupal-link-system-path="news-events/science-highlights"> <span>Science Highlights</span>
|
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<li class="usa-nav__submenu-item">
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<a href="/news-events/nibib-news" target="_self" class="link" data-drupal-link-system-path="news-events/nibib-news"> <span>NIBIB in the News</span>
|
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</a>
|
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|
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</li>
|
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|
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</ul>
|
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</div>
|
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<div class="desktop:grid-col-4 submenu-list-container">
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<div class="usa-nav__submenu-item">
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<span class="nolink"> <span class="usa-nav__submenu-heading">EVENTS</span>
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</span>
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<ul id="basic-nav-section-2" class="usa-nav__submenu-list">
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<a href="/news-events/meetings-events/upcoming-events" class="link" data-drupal-link-system-path="news-events/meetings-events/upcoming-events"> <span>Upcoming Events</span>
|
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</a>
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<li class="usa-nav__submenu-item">
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<a href="/news-events/meetings-events/past-events" class="link" data-drupal-link-system-path="news-events/meetings-events/past-events"> <span>Past Events</span>
|
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</a>
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</li>
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<li class="usa-nav__submenu-item">
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<a href="/news-events/meetings-events/photo-galleries" class="link" data-drupal-link-system-path="news-events/meetings-events/photo-galleries"> <span>Event Photos</span>
|
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</a>
|
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|
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</li>
|
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|
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</ul>
|
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|
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|
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</div>
|
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<div class="desktop:grid-col-4 submenu-list-container">
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<div class="usa-nav__submenu-item">
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<span target="_self" class="nolink"> <span class="usa-nav__submenu-heading">MEDIA RESOURCES</span>
|
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</span>
|
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</div>
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<ul id="basic-nav-section-3" class="usa-nav__submenu-list">
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<li class="usa-nav__submenu-item">
|
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|
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|
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|
||
|
||
<a href="/science-education/science-topics" target="_self" class="link" data-drupal-link-system-path="node/131271"> <span>Science Topics</span>
|
||
</a>
|
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|
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</li>
|
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|
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|
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|
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|
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<li class="usa-nav__submenu-item">
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|
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|
||
<a href="mailto:nibibpress@mail.nih.gov" target="_self" class="link"> <span>Contact Us</span>
|
||
</a>
|
||
|
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</li>
|
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|
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|
||
</ul>
|
||
|
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|
||
|
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|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
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</li>
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<li class="usa-nav__primary-item">
|
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<button type="button" class="usa-accordion__button usa-nav__link " aria-expanded="false" aria-controls="extended-mega-nav-section-6">
|
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<span>About NIBIB </span>
|
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</button>
|
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<div id="extended-mega-nav-section-6" class="usa-nav__submenu usa-megamenu" hidden="">
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<div class="grid-row mm-container">
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<div class="desktop:grid-col flex-auto duplicated-parent">
|
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<div class="usa-nav__submenu-item">
|
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<span><a href="/about-nibib" target="_self" class="link" data-drupal-link-system-path="node/156676">About NIBIB</a> <span class="uswds-arrow-forward"></span></span>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
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<div class="grid-row mm-container">
|
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|
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|
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|
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<div class="desktop:grid-col-4 submenu-list-container">
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<div class="usa-nav__submenu-item">
|
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<span target="_self" class="nolink"> <span class="usa-nav__submenu-heading">WHO WE ARE</span>
|
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</span>
|
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</div>
|
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|
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<ul id="basic-nav-section-1" class="usa-nav__submenu-list">
|
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<li class="usa-nav__submenu-item">
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|
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|
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|
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<a href="/about-nibib/mission" target="_self" class="link" data-drupal-link-system-path="node/79861"> <span>Mission & History</span>
|
||
</a>
|
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|
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</li>
|
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|
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<li class="usa-nav__submenu-item">
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|
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|
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|
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|
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<a href="/about-nibib/directors-corner" target="_self" class="link" data-drupal-link-system-path="node/121791"> <span>Director's Corner</span>
|
||
</a>
|
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|
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</li>
|
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|
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<li class="usa-nav__submenu-item">
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|
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|
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|
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<a href="/about-nibib/organizational-chart" target="_self" class="link" data-drupal-link-system-path="node/18836"> <span>Organization Chart</span>
|
||
</a>
|
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|
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</li>
|
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<li class="usa-nav__submenu-item">
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|
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|
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|
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|
||
<a href="/about-nibib/advisory-council" target="_self" class="link" data-drupal-link-system-path="node/876"> <span>Advisory Council</span>
|
||
</a>
|
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|
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</li>
|
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|
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|
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|
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<li class="usa-nav__submenu-item">
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|
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|
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|
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|
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<a href="/about-nibib/careers-at-NIBIB" target="_self" class="link" data-drupal-link-system-path="node/131241"> <span>Jobs @ NIBIB</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
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|
||
</ul>
|
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|
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|
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|
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|
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</div>
|
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|
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|
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<div class="desktop:grid-col-4 submenu-list-container">
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<div class="usa-nav__submenu-item">
|
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<span target="_self" class="nolink"> <span class="usa-nav__submenu-heading">WHAT WE DO</span>
|
||
</span>
|
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</div>
|
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|
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|
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|
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<ul id="basic-nav-section-2" class="usa-nav__submenu-list">
|
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<li class="usa-nav__submenu-item">
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|
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|
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|
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|
||
<a href="/about-nibib/strategic-plan" target="_self" class="link" data-drupal-link-system-path="node/11846"> <span>Strategic Plan</span>
|
||
</a>
|
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|
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</li>
|
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|
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<li class="usa-nav__submenu-item">
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|
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|
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|
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|
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<a href="/about-nibib/budget" target="_self" class="link" data-drupal-link-system-path="node/911"> <span>Budget</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
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|
||
</ul>
|
||
|
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|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
|
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</ul>
|
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|
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|
||
|
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|
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|
||
|
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|
||
<div class="usa-nav__secondary">
|
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<div>
|
||
<section aria-label="search component" id="nibib-header-search" data-drupal-selector="search-block-form" role="search">
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<form id="search-block-form" accept-charset="UTF-8" class="usa-search usa-search--small" role="search" action="/searching" method="get">
|
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<label class="usa-sr-only" for="search-field-en-small">Search</label>
|
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<input aria-label="Search" class="usa-input" id="edit-keys" data-drupal-selector="edit-keys" data-original-title="Enter the terms you wish to search for." data-toggle="tooltip" type="search" name="q" value="" tabindex="-1"/>
|
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<button class="usa-button js-form-submit form-submit" name="search_btn" type="submit" value="Search" tabindex="-1">
|
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<img src="/themes/custom/nibib/assets/uswds/img/usa-icons-bg/search--white.svg" class="usa-search__submit-icon" alt="Search" />
|
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</button>
|
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</form>
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</section>
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</div>
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|
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<ul class="header-nav__secondary-list">
|
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<li class="header-nav__secondary-item">
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<a href="/es/nibib-en-espanol"> En Español
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</a>
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</li>
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<li class="header-nav__secondary-item">
|
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<a target="_blank" class="link-list-serve" href="https://public.govdelivery.com/accounts/USNIBIB/subscriber/edit?preferences=true#tab1"> Join LISTSERV
|
||
</a>
|
||
</li>
|
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</ul>
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|
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|
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</div>
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</div>
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</nav>
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</header>
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|
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<main class="main-content usa-layout-docs usa-section " role="main" id="main-content">
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<div class="grid-container">
|
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<div class="grid-row breadcrumb-social-share-bar">
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<div class="tablet:grid-col-6 desktop:grid-col-8">
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<div>
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<div id="block-breadcrumbs" class="block block-system block-system-breadcrumb-block">
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<nav class="usa-breadcrumb--wrap" role="navigation" aria-label="breadcrumb">
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<ol class="usa-breadcrumb__list">
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<li class="usa-breadcrumb__list-item">
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<a href="/" class="usa-breadcrumb__link"><span>Home</span></a>
|
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</li>
|
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<li class="usa-breadcrumb__list-item">
|
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<a href="/news-events" class="usa-breadcrumb__link"><span>News & Events</span></a>
|
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</li>
|
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<li class="usa-breadcrumb__list-item">
|
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<a href="/news-events/newsroom" class="usa-breadcrumb__link"><span>Newsroom</span></a>
|
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</li>
|
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</ol>
|
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</nav>
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</div>
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</div>
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</div>
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<div class="tablet:grid-col-6 desktop:grid-col-4">
|
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<div>
|
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|
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<div id="block-addtoanysharebuttons" class="block block-addtoany block-addtoany-block">
|
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|
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|
||
<span class="a2a_kit a2a_kit_size_32 addtoany_list" data-a2a-url="https://www.nibib.nih.gov/news-events/newsroom/nih%E2%80%99s-radx-tech-program-inks-additional-contracts-covid-19-diagnostic-tests-and-supplies" data-a2a-title="NIH’s RADx Tech program inks additional contracts for COVID-19 diagnostic tests and supplies "><a class="a2a_button_email"><span class="a2a_svg a2a_s_a2a a2a_s_email a2a-box"><img src="/themes/custom/nibib/assets/img/email-a2a.svg" border="0" alt="Facebook" width="27" height="27"></span></a><a class="a2a_button_facebook"><span class="a2a_svg a2a_s_a2a a2a_s_facebook a2a-box"><img src="/themes/custom/nibib/assets/img/facebook-a2a.svg" border="0" alt="Facebook" width="27" height="27"></span></a><a class="a2a_button_linkedin"><span class="a2a_svg a2a_s_a2a a2a_s_linkedin a2a-box"><img src="/themes/custom/nibib/assets/img/linkedin-a2a.svg" border="0" alt="Facebook" width="27" height="27"></span></a><a class="a2a_button_twitter"><span class="a2a_svg a2a_s_a2a a2a_s_x a2a-box"><img src="/themes/custom/nibib/assets/img/x-a2a.svg" border="0" alt="Facebook" width="27" height="27"></span
|
||
</a><a class="a2a_button_whatsapp"><span class="a2a_svg a2a_s_a2a a2a_s_whatsapp a2a-box"><img src="/themes/custom/nibib/assets/img/whatsapp-a2a.svg" border="0" alt="Facebook" width="27" height="27"></span></a><a class="a2a_dd addtoany_share"><span class="a2a_svg a2a_s_a2a a2a_s_share a2a-box"><img src="/themes/custom/nibib/assets/img/share-a2a.svg" border="0" alt="Share" width="27" height="27"></span></a></span>
|
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|
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</div>
|
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</div>
|
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|
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</div>
|
||
</div>
|
||
|
||
<div class="">
|
||
<div data-drupal-messages-fallback class="hidden"></div>
|
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|
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|
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</div>
|
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|
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<div class="grid-row ">
|
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|
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</div>
|
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|
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<div class="grid-row grid-gap">
|
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|
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<div class="usa-layout-docs__main desktop:grid-col-fill">
|
||
|
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<div id="block-nibib-page-title" class="block--page-title-block">
|
||
|
||
|
||
<h1 class="margin-0 page-header">
|
||
<span>NIH’s RADx Tech program inks additional contracts for COVID-19 diagnostic tests and supplies </span>
|
||
</h1>
|
||
|
||
</div>
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<article data-history-node-id="123511" about="/news-events/newsroom/nih%E2%80%99s-radx-tech-program-inks-additional-contracts-covid-19-diagnostic-tests-and-supplies" class="news node node--type-news is-promoted full clearfix">
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<div class="content">
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<div class="grid-col flex-auto news--type-date"><strong>
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<div class="field field--name-field-news-type field--type-entity-reference field--label-hidden field__item">Science Highlights</div>
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</strong></div>
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<div class="grid-col flex-auto news--type-date"><strong>
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<div class="field field--name-field-publication-date field--type-datetime field--label-hidden field__item">January 12, 2021</div>
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</strong></div>
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</div>
|
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<h3> New awards expand the range of diagnostic testing platforms and address supply shortages </h3>
|
||
|
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<div id="node--news--more-from-author">
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<h3>Media Contacts</h3>
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<p>Patricia Wiley<br/>
|
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<a href="mailto:nibibpress@mail.nih.gov">nibibpress@mail.nih.gov</a><br/>
|
||
<a href="tel:301-496-3500">301-496-3500</a><br/>
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<a href="/more-content-by/patricia-wiley">More by this author</a></p>
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</div>
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||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The National Institutes of Health has awarded three new contracts totaling $36.7 million for the development of new COVID-19 diagnostic testing technologies and production of specimen collection kits and swabs. The <a href="https://www.nih.gov/research-training/medical-research-initiatives/radx">Rapid Acceleration of Diagnostics (RADx) initiative</a> has advanced the scale-up of 25 testing projects since July 2020, which now include lab-based, point-of-care, and potential at-home formats. </p>
|
||
<div class="pull-quote-right pull-quote blue-green">NIH launched the RADx<sup>SM</sup> initiative to speed innovation for COVID-19 testing. There are four RADx programs: </p>
|
||
<ul>
|
||
<li><a href="https://www.nih.gov/research-training/medical-research-initiatives/radx/radx-programs#radx-atp">RADx Advanced Technologies Platforms (RADx ATP)</a></li>
|
||
<li><a href="https://www.nih.gov/research-training/medical-research-initiatives/radx/radx-programs#radx-tech">RADx Tech </a></li>
|
||
<li><a href="https://www.nih.gov/research-training/medical-research-initiatives/radx/radx-programs#radx-up">RADx Underserved Populations (RADx-UP)</a></li>
|
||
<li><a href="https://www.nih.gov/research-training/medical-research-initiatives/radx/radx-programs#radx-rad">RADx Radical (RADx-rad)</a></li>
|
||
</ul>
|
||
</div>
|
||
<p>During a 15-week span earlier this year, the RADx Tech program solicited and received more than 700 proposals from diagnostic device developers at universities and businesses—from start-ups to large companies—proposing new diagnostic technology concepts to address the urgent need for COVID-19 testing. The program qualified 137 of the proposed ideas to enter a deep dive evaluation, of which 47 emerged for further development and validation. The newly awarded projects move now to the next phase of scale-up and commercialization.</p>
|
||
<p>“NIH’s RADx initiative has sparked innovation and produced an impressive array of COVID-19 test platforms—from lab-based to point-of-care, and soon to follow at-home tests,” said Bruce Tromberg, Ph.D., director of the National Institute of Biomedical Imaging and Bioengineering (NIBIB), and leader of RADx Tech, one of the four components of the NIH RADx initiative. “Along with sophisticated diagnostic tools, we also have tapped into products that address supply shortages, continuing our support to speed and augment public health efforts to contain the virus and return the nation to normal activities.”</p>
|
||
<p>This announcement includes testing technologies for the point-of-care, as well as the potential for at-home test administration. As well, RADx Tech announced support for technologies that will enhance the collection of specimens, an integral aspect of the diagnostic testing process.</p>
|
||
<h3>New sample collection methods to overcome swab shortages</h3>
|
||
<figure role="group" class="align-left">
|
||
<img alt="COVID19 testing technologies and supplies" data-entity-type="file" data-entity-uuid="45870791-2463-4580-8176-c95a09c5fcf6" height="270" src="/sites/default/files/inline-images/Fourth%20RADx%20phase%20twos%20lg%20th%20360%20x%20228.jpg" width="430" loading="lazy"></p>
|
||
<figcaption>Among the technologies being supported by the RADx initiative to advance COVID-19 testing are a 15-minute, lateral-flow rapid antigen test and innovative sample-collection swabs. Photos courtesy of ANP Technologies (left); Yukon Medical (right).</figcaption>
|
||
</figure>
|
||
<p>Shortages of essential supplies—from personal protective equipment for healthcare workers and ventilators for patients—have compounded already difficult logistics in responding to the COVID-19 pandemic in the United States. With increased demand for diagnostic tests, supply deficits for specimen collection swabs and kits have also posed problems. RADx support for alternatives to standard swabs will help meet the high demand and alleviate supply bottlenecks.</p>
|
||
<h4>Oasis Diagnostics Corporation, Vancouver, Washington</h4>
|
||
<p>Unique saliva and cheek swab collection kits used with multiple types of testing platforms, such as RT-PCR, antigen, and next-generation sequencing. The collection kits purify saliva specimens, mitigating various problems related to viscosity and impurities. The collection kit can be used for at-home, self-collection, or at the point-of-need, as samples remain stable at room temperature.</p>
|
||
<h4>Yukon Medical, Durham, North Carolina</h4>
|
||
<p>Three swab types<a name="_Hlk60822847">—</a>for nasal, mid-turbinate, and nasopharyngeal samples—are designed for optimal sample collection and maximum release and can be used with multiple testing methods. The swabs also have a breakpoint that can be customized to the specific diagnostic test to reduce the risk of sample contamination. Nasopharyngeal swabs require administration by a healthcare professional, mid-turbinate swabbing requires clinical observation, and nasal swabs allow at-home, self-collection.</p>
|
||
<h3>New rapid antigen tests for point of care with potential at-home test formats</h3>
|
||
<h4>ANP Technologies, Newark, Delaware</h4>
|
||
<p>A lateral flow immunoassay platform technology that detects SARS-CoV-2 antigens in nasal samples. The rapid antigen test delivers results in 15 minutes at the point of care and is being validated for potential at-home use.</p>
|
||
<h4>Quidel, San Diego</h4>
|
||
<p>RADx Advanced Technology Platforms (RADx-ATP) expanded its earlier contract with Quidel to now include the QuickVue SARS Antigen Test, for which the U.S. Food and Drug Administration granted emergency use authorization on Dec. 18, 2020, for use in point-of-care settings. (The original contract announced this past summer was for Quidel’s Sofia SARS Antigen FIA test kit.)</p>
|
||
<p>The QuickVue test uses a dipstick—a simple paper-like test strip that is dipped into a specimen tube—to detect SARS-CoV-2 antigens in nasal samples. Results are displayed in 10 minutes without a specialized electronic reader. It will be offered for a competitive price and in quantities that permit broad distribution in the United States. The test is undergoing further validation for potential at-home use.</p>
|
||
<hr>
|
||
<p>The NIH RADx initiative is comprised of <a href="https://www.nih.gov/research-training/medical-research-initiatives/radx/radx-programs">four programs</a> that address COVID-19 pandemic challenges and corresponding responses from the scientific community. The RADx Tech and the RADx Advanced Technology Program leverage the Point-of-Care Technology Research Network (POCTRN) administered by NIBIB and spanning multiple leading universities, to manage, evaluate, and validate technologies. In addition, RADx initiative partnerships with federal agencies, including the Biomedical Advanced Research and Development Authority, the Office of the Assistant Secretary of Health, Department of Defense, and FDA are critical to RADx initiative success.</p>
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