2130 lines
77 KiB
Text
2130 lines
77 KiB
Text
<!DOCTYPE html>
|
||
<html lang="en" dir="ltr" prefix="content: http://purl.org/rss/1.0/modules/content/ dc: http://purl.org/dc/terms/ foaf: http://xmlns.com/foaf/0.1/ og: http://ogp.me/ns# rdfs: http://www.w3.org/2000/01/rdf-schema# schema: http://schema.org/ sioc: http://rdfs.org/sioc/ns# sioct: http://rdfs.org/sioc/types# skos: http://www.w3.org/2004/02/skos/core# xsd: http://www.w3.org/2001/XMLSchema# ">
|
||
<head>
|
||
<meta charset="utf-8" />
|
||
<meta name="description" content="Researchers are developing new MRI contrast agents that are activated in low oxygen environments enabling improved diagnosis and treatment of hypoxic tumors as well as other diseases." />
|
||
<meta name="keywords" content="Cancer Imaging tracer,Magnetic Resonance Imaging (MRI)" />
|
||
<link rel="canonical" href="https://www.nibib.nih.gov/news-events/newsroom/mri-contrast-agent-targets-hypoxic-disease" />
|
||
<link rel="shortlink" href="https://www.nibib.nih.gov/node/142226" />
|
||
<meta name="generator" content="Drupal 8 (http://drupal.org)" />
|
||
<meta property="og:site_name" content="National Institute of Biomedical Imaging and Bioengineering" />
|
||
<meta property="og:title" content="MRI contrast agent targets hypoxic disease" />
|
||
<meta property="og:description" content="Researchers are developing new MRI contrast agents that are activated in low oxygen environments enabling improved diagnosis and treatment of hypoxic tumors as well as other diseases." />
|
||
<meta property="og:image" content="https://www.nibib.nih.gov/sites/default/files/2023-03/Hypoxia-FBTW-800x418_0.jpg" />
|
||
<meta name="twitter:card" content="summary_large_image" />
|
||
<meta name="twitter:site" content="@NIBIBgov" />
|
||
<meta name="twitter:title" content="MRI contrast agent targets hypoxic disease" />
|
||
<meta name="twitter:description" content="Researchers are developing new MRI contrast agents that are activated in low oxygen environments enabling improved diagnosis and treatment of hypoxic tumors as well as other diseases." />
|
||
<meta name="twitter:image:alt" content="A computer generated image of a tumor with blood vessels and the words "imaging hypoxia"" />
|
||
<meta name="twitter:image" content="https://www.nibib.nih.gov/sites/default/files/2023-03/Hypoxia-FBTW-800x418_1.jpg" />
|
||
<meta name="Generator" content="Drupal 10 (https://www.drupal.org)" />
|
||
<meta name="MobileOptimized" content="width" />
|
||
<meta name="HandheldFriendly" content="true" />
|
||
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
|
||
<link rel="icon" href="/themes/custom/nibib/assets/img/favicon-2024.ico" type="image/vnd.microsoft.icon" />
|
||
<script>window.a2a_config=window.a2a_config||{};a2a_config.callbacks=[];a2a_config.overlays=[];a2a_config.templates={};</script>
|
||
|
||
<title>MRI contrast agent targets hypoxic disease</title>
|
||
<link rel="stylesheet" media="all" href="/sites/default/files/css/css_PGHNMkCzMAYVG6Ibanv-jaFgOXnu9K-JOmZ4DdEVBvQ.css?delta=0&language=en&theme=nibib&include=eJyFUNFuwzAI_CEr-SSEbZLSuGAZ0iV_Pyftpk6KtBd0hw7uAHN2RdlHfINhaioe0IwcWO6UXNuYzIa0UOZOoBM4oF2phL4MfK90yoQod6oQCRo99En5aqiiUIFXjau7CjzZOBa6UjcywpZuMK2SWWZoPN8cjDPBxNtp-r-nN2Q5prVWbb4KO5NB_8N53BE_REzLscm1jh8YOKmE33-wZBKPRdMyfuCQtNGY21qxDHjH7U8jMxadA21eWJaf7puGiYtTz4nVuVsJR47jeYQF283p0fMYfQOUirET" />
|
||
<link rel="stylesheet" media="all" href="/sites/default/files/css/css_aEF6OqZqjqJLoh0a2euYBizjn0L0bvyOyKjN-8ltJN4.css?delta=1&language=en&theme=nibib&include=eJyFUNFuwzAI_CEr-SSEbZLSuGAZ0iV_Pyftpk6KtBd0hw7uAHN2RdlHfINhaioe0IwcWO6UXNuYzIa0UOZOoBM4oF2phL4MfK90yoQod6oQCRo99En5aqiiUIFXjau7CjzZOBa6UjcywpZuMK2SWWZoPN8cjDPBxNtp-r-nN2Q5prVWbb4KO5NB_8N53BE_REzLscm1jh8YOKmE33-wZBKPRdMyfuCQtNGY21qxDHjH7U8jMxadA21eWJaf7puGiYtTz4nVuVsJR47jeYQF283p0fMYfQOUirET" />
|
||
<link rel="stylesheet" media="all" href="/sites/default/files/css/css_11GMEshzEGbOCSQllNQaVK4LkoqZwZLhLy6lyXEy8Gc.css?delta=2&language=en&theme=nibib&include=eJyFUNFuwzAI_CEr-SSEbZLSuGAZ0iV_Pyftpk6KtBd0hw7uAHN2RdlHfINhaioe0IwcWO6UXNuYzIa0UOZOoBM4oF2phL4MfK90yoQod6oQCRo99En5aqiiUIFXjau7CjzZOBa6UjcywpZuMK2SWWZoPN8cjDPBxNtp-r-nN2Q5prVWbb4KO5NB_8N53BE_REzLscm1jh8YOKmE33-wZBKPRdMyfuCQtNGY21qxDHjH7U8jMxadA21eWJaf7puGiYtTz4nVuVsJR47jeYQF283p0fMYfQOUirET" />
|
||
|
||
|
||
<!-- Google Tag Manager -->
|
||
<script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':
|
||
new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],
|
||
j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src=
|
||
'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);
|
||
})(window,document,'script','dataLayer','GTM-T4JGL8');</script>
|
||
<!-- End Google Tag Manager -->
|
||
</head>
|
||
<body class="fontyourface">
|
||
<a href="#main-content" class="usa-sr-only focusable">
|
||
Skip to main content
|
||
</a>
|
||
|
||
<div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas>
|
||
|
||
|
||
|
||
|
||
<section class="usa-banner">
|
||
<div class="usa-overlay"></div>
|
||
<section class="usa-banner" aria-label="Official website of the United States government">
|
||
<div class="usa-accordion">
|
||
<header class="usa-banner__header">
|
||
<div class="usa-banner__inner">
|
||
<div class="grid-col-auto">
|
||
<img
|
||
aria-hidden="true" class="usa-banner__header-flag" src="/themes/custom/nibib/assets/uswds/img/us_flag_small.png" alt="USA flag"/>
|
||
</div>
|
||
<div class="grid-col-fill tablet:grid-col-auto" aria-hidden="true">
|
||
<p class="usa-banner__header-text">
|
||
An official website of the United States government
|
||
</p>
|
||
<p class="usa-banner__header-action">Here’s how you know</p>
|
||
</div>
|
||
<button type="button" class="usa-accordion__button usa-banner__button" aria-expanded="false" aria-controls="gov-banner-default-default">
|
||
<span class="usa-banner__button-text">Here’s how you know</span>
|
||
</button>
|
||
</div>
|
||
</header>
|
||
<div class="usa-banner__content usa-accordion__content" id="gov-banner-default-default">
|
||
<div class="grid-row grid-gap-lg">
|
||
<div class="usa-banner__guidance mobile-lg:grid-col-6 tablet:grid-col-4 desktop:grid-col-3">
|
||
<img class="usa-banner__icon usa-media-block__img " src="/themes/custom/nibib/assets/uswds/img/icon-dot-gov.svg" role="img" alt="Dot gov icon" aria-hidden="true"/>
|
||
<div class="usa-media-block__body">
|
||
<p>
|
||
<strong>Official websites use .gov</strong><br/>A
|
||
<strong>.gov</strong>
|
||
website belongs to an official government organization in the United States.</p>
|
||
</div>
|
||
</div>
|
||
<div class="usa-banner__guidance mobile-lg:grid-col-6 tablet:grid-col-4 desktop:grid-col-3">
|
||
<img class="usa-banner__icon usa-media-block__img" src="/themes/custom/nibib/assets/uswds/img/icon-https.svg" role="img" alt="Lock Icon" aria-hidden="true"/>
|
||
<div class="usa-media-block__body">
|
||
<p>
|
||
<strong>Secure .gov websites use HTTPS</strong><br/>A
|
||
<strong>lock</strong>
|
||
(
|
||
<span class="icon-lock">
|
||
<svg xmlns="http://www.w3.org/2000/svg" width="52" height="64" viewbox="0 0 52 64" class="usa-banner__lock-image" role="img" aria-labelledby="banner-lock-description-default" focusable="false">
|
||
<title id="banner-lock-title-default">Lock</title>
|
||
<desc id="banner-lock-description-default">Locked padlock icon</desc>
|
||
<path fill="#000000" fill-rule="evenodd" d="M26 0c10.493 0 19 8.507 19 19v9h3a4 4 0 0 1 4 4v28a4 4 0 0 1-4 4H4a4 4 0 0 1-4-4V32a4 4 0 0 1 4-4h3v-9C7 8.507 15.507 0 26 0zm0 8c-5.979 0-10.843 4.77-10.996 10.712L15 19v9h22v-9c0-6.075-4.925-11-11-11z"/>
|
||
</svg>
|
||
</span>) or
|
||
<strong>https://</strong>
|
||
means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.</p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</section>
|
||
</section>
|
||
|
||
<div class="usa-overlay"></div>
|
||
|
||
<header class="usa-header usa-header--extended usa-header--extended-megamenu " id="header" role="banner">
|
||
<div class="region region-header usa-navbar desktop:padding-y-1 desktop:padding-x-0">
|
||
|
||
<div class="usa-logo site-logo" id="logo">
|
||
<a class="logo-img" href="/" accesskey="1" title="National Instititue of Biomedical Imaging and Bioengineering (NIBIB), Home" aria-label="Home">
|
||
<img src="/sites/default/files/NIBIB_Logo_Master_2023.svg" alt="National Instititue of Biomedical Imaging and Bioengineering (NIBIB), Home" />
|
||
</a>
|
||
</div>
|
||
<button type="button" class="usa-menu-btn">Menu</button>
|
||
</div>
|
||
|
||
<nav aria-label="Primary navigation" class="usa-nav">
|
||
<div class="usa-nav__inner">
|
||
<button type="button" class="usa-nav__close">
|
||
<img src="/themes/custom/nibib/assets/uswds/img/usa-icons/close.svg" role="img" alt="Close"/>
|
||
</button>
|
||
|
||
|
||
|
||
|
||
|
||
<ul class="usa-nav__primary usa-accordion">
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__primary-item">
|
||
|
||
<button type="button" class="usa-accordion__button usa-nav__link " aria-expanded="false" aria-controls="extended-mega-nav-section-1">
|
||
<span>Funding </span>
|
||
</button>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div id="extended-mega-nav-section-1" class="usa-nav__submenu usa-megamenu" hidden="">
|
||
|
||
<div class="grid-row mm-container">
|
||
<div class="desktop:grid-col flex-auto duplicated-parent">
|
||
<div class="usa-nav__submenu-item">
|
||
<span><a href="/funding" class="link" data-drupal-link-system-path="node/156661">Funding</a> <span class="uswds-arrow-forward"></span></span>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="grid-row mm-container">
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span class="nolink"> <span class="usa-nav__submenu-heading">FUNDING OPPORTUNITIES</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-1" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/funding/opportunities/all" class="link" data-drupal-link-system-path="funding/opportunities/all"> <span>All Funding Opportunities</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/funding/opportunities/research" class="link" data-drupal-link-system-path="funding/opportunities/research"> <span>Research Opportunities</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/funding/opportunities/training" class="link" data-drupal-link-system-path="funding/opportunities/training"> <span>Training Opportunities</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/funding/opportunities/small-business" class="link" data-drupal-link-system-path="funding/opportunities/small-business"> <span>Small Business Opportunities</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/funding/opportunities/limited-resource-Institutions" class="link" data-drupal-link-system-path="funding/opportunities/limited-resource-Institutions"> <span>Limited-resource Institutions</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span class="nolink"> <span class="usa-nav__submenu-heading">FUNDING RESOURCES</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-2" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/funding/notices" class="link" data-drupal-link-system-path="funding/notices"> <span>Funding Notices</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/funding/policies" target="_self" class="link" data-drupal-link-system-path="node/147366"> <span>Funding Policies</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/funding/nibib-data-management-sharing" class="link" data-drupal-link-system-path="node/138366"> <span>NIBIB Data Management and Sharing </span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/funding/resources" target="_self" class="link" data-drupal-link-system-path="node/147391"> <span>Research Resources</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__primary-item">
|
||
|
||
<button type="button" class="usa-accordion__button usa-nav__link " aria-expanded="false" aria-controls="extended-mega-nav-section-2">
|
||
<span>Research & Training Programs </span>
|
||
</button>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div id="extended-mega-nav-section-2" class="usa-nav__submenu usa-megamenu" hidden="">
|
||
|
||
<div class="grid-row mm-container">
|
||
<div class="desktop:grid-col flex-auto duplicated-parent">
|
||
<div class="usa-nav__submenu-item">
|
||
<span><a href="/programs" class="link" data-drupal-link-system-path="node/156656">Research & Training Programs</a> <span class="uswds-arrow-forward"></span></span>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="grid-row mm-container">
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span class="nolink"> <span class="usa-nav__submenu-heading">PROGRAMS</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-1" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/division-applied-science-technology-dast" target="_self" class="link" data-drupal-link-system-path="node/41841"> <span>Biomedical Imaging</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/division-discovery-science-technology-ddst" target="_self" class="link" data-drupal-link-system-path="node/142251"> <span>Bioengineering</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/division-health-informatics-technologies-dhit" target="_self" class="link" data-drupal-link-system-path="node/41846"> <span>Informatics</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/division-interdisciplinary-training-didt" class="link" data-drupal-link-system-path="node/47546"> <span>Training</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/small-business-programs" class="link" data-drupal-link-system-path="node/156681"> <span>Small Business</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span class="nolink"> <span class="usa-nav__submenu-heading">COLLABORATIONS TO ACCELERATE TECHNOLOGY</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-2" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/radx-innovation-funnel" class="link" data-drupal-link-system-path="node/146966"> <span>RADx Tech Innovation Funnel</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/interagency-modeling-analysis-group-imag" class="link" data-drupal-link-system-path="node/121821"> <span>Interagency Modeling and Analysis Group (IMAG)</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/point-care-technologies-research-network" class="link" data-drupal-link-system-path="node/121936"> <span>Point-of-Care Technology Network (POCTRN)</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/medical-imaging-data-resource-center" class="link" data-drupal-link-system-path="node/127326"> <span>Medical Imaging Data Resource (MIDRC)</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/radx-tech-program/mars" class="link" data-drupal-link-system-path="node/133076"> <span>RADx Mobile At-home Reporting (MARS)</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/programs/national-centers-biomedical-imaging-bioengineering" class="link" data-drupal-link-system-path="node/143396"> <span>National Technology Centers Program (P41)</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__primary-item">
|
||
|
||
<button type="button" class="usa-accordion__button usa-nav__link " aria-expanded="false" aria-controls="extended-mega-nav-section-3">
|
||
<span>Labs @ NIBIB </span>
|
||
</button>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div id="extended-mega-nav-section-3" class="usa-nav__submenu usa-megamenu" hidden="">
|
||
|
||
<div class="grid-row mm-container">
|
||
<div class="desktop:grid-col flex-auto duplicated-parent">
|
||
<div class="usa-nav__submenu-item">
|
||
<span><a href="/labs-at-nibib" class="link" data-drupal-link-system-path="node/156726">Labs @ NIBIB</a> <span class="uswds-arrow-forward"></span></span>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="grid-row mm-container">
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span class="nolink"> <span class="usa-nav__submenu-heading">RESOURCES AND CORES</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-1" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/center-for-biomedical-engineering-technology-acceleration-beta" class="link" data-drupal-link-system-path="node/140991"> <span>BETA Center</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/advanced-imaging-and-microscopy-aim-resource" target="_self" class="link" data-drupal-link-system-path="node/69321"> <span>Advanced Imaging/Microscopy</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/trans-nih-shared-resource-biomedical-engineering-and-physical-science-beps" target="_self" class="link" data-drupal-link-system-path="node/13551"> <span>Biomed Engineering/Physical Science</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/ideas-lab" class="link" data-drupal-link-system-path="node/135571"> <span>IDEAS Resource</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/molecular-tracer-and-imaging-core-facility" class="link" data-drupal-link-system-path="node/138926"> <span>Molecular Tracer and Imaging Core</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span class="nolink"> <span class="usa-nav__submenu-heading">LABS</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-2" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/laboratory-cellular-imaging-and-macromolecular-biophysics-lcimb" target="_self" class="link" data-drupal-link-system-path="node/141566"> <span>Cellular Imaging</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/dynamics-macromolecular-assembly" class="link" data-drupal-link-system-path="node/138901"> <span>Dynamics of Macromolecular Assembly</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/section-immunoengineering" class="link" data-drupal-link-system-path="node/138956"> <span>Immunoengineering</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/section-mechanics-tissue-remodeling-integrating-computational-experimental-systems" target="_self" class="link" data-drupal-link-system-path="node/144586"> <span>Mechanics and Tissue Remodeling</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/section-mechanobiology" class="link" data-drupal-link-system-path="node/138971"> <span>Mechanobiology</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/quantitative-medical-imaging" target="_self" class="link" data-drupal-link-system-path="node/138916"> <span>Quantitative Imaging</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span target="_self" class="nolink"> <span class="usa-nav__submenu-heading">RELATED LINKS</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-3" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/besip" target="_self" class="link" data-drupal-link-system-path="node/34251"> <span>Summer Internship at NIBIB</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/labs-at-nibib/nibib-board-scientific-counselors" target="_self" class="link" data-drupal-link-system-path="node/32501"> <span>Board of Scientific Counselors</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__primary-item">
|
||
|
||
<button type="button" class="usa-accordion__button usa-nav__link " aria-expanded="false" aria-controls="extended-mega-nav-section-4">
|
||
<span>Science Education </span>
|
||
</button>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div id="extended-mega-nav-section-4" class="usa-nav__submenu usa-megamenu" hidden="">
|
||
|
||
<div class="grid-row mm-container">
|
||
<div class="desktop:grid-col flex-auto duplicated-parent">
|
||
<div class="usa-nav__submenu-item">
|
||
<span><a href="/science-education" target="_self" class="link" data-drupal-link-system-path="node/156666">Science Education</a> <span class="uswds-arrow-forward"></span></span>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="grid-row mm-container">
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span target="_self" class="nolink"> <span class="usa-nav__submenu-heading">SCIENCE TOPICS</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-1" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/artificial-intelligence-ai" class="link" data-drupal-link-system-path="node/114791"> <span>Artificial Intelligence (AI)</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/biomaterial-technologies" class="link" data-drupal-link-system-path="node/156766"> <span>Biomaterial Technologies</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/computational-modeling" class="link" data-drupal-link-system-path="node/31416"> <span>Computational Modeling</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/computed-tomography-ct" class="link" data-drupal-link-system-path="node/18996"> <span>Computed Tomography (CT) </span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/magnetic-resonance-imaging-mri" target="_self" class="link" data-drupal-link-system-path="node/18786"> <span>Magnetic Resonance Imaging (MRI)</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/mammography" class="link" data-drupal-link-system-path="node/19036"> <span>Mammography</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/medical-device-technologies" class="link" data-drupal-link-system-path="node/156341"> <span>Medical Device Technologies</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/medical-simulators" class="link" data-drupal-link-system-path="node/156431"> <span>Medical Simulators</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span class="nolink"> <span class="usa-nav__submenu-heading">SCIENCE TOPICS cont…</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-2" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/nuclear-medicine" target="_self" class="link" data-drupal-link-system-path="node/18831"> <span>Nuclear Medicine</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/optical-imaging" target="_self" class="link" data-drupal-link-system-path="node/31426"> <span>Optical Imaging</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/rapid-diagnostics" class="link" data-drupal-link-system-path="node/157006"> <span>Rapid Diagnostics</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/rehabilitation-engineering" class="link" data-drupal-link-system-path="node/30891"> <span>Rehabilitation Engineering</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/robotic-and-bionic-medical-devices" target="_self" class="link" data-drupal-link-system-path="node/153676"> <span>Robotic and Bionic Medical Devices</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/sensors" class="link" data-drupal-link-system-path="node/34241"> <span>Sensors</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/telehealth" class="link" data-drupal-link-system-path="node/33346"> <span>Telehealth</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/ultrasound" target="_self" class="link" data-drupal-link-system-path="node/18766"> <span>Ultrasound</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics/x-rays" target="_self" class="link" data-drupal-link-system-path="node/19176"> <span>X-Rays</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span class="nolink"> <span class="usa-nav__submenu-heading">EXPLORE and LEARN</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-3" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/Understanding-Medical-Scans-App" target="_self" class="link" data-drupal-link-system-path="node/68546"> <span>Medical Imaging App</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/beams-challenge" class="link" data-drupal-link-system-path="node/143486"> <span>Lesson Plans</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/meet-a-scientist" class="link" data-drupal-link-system-path="node/141721"> <span>Meet a Scientist</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="https://www.youtube.com/playlist?list=PLYH1eUq1QYrqrvA6HRRgKHcPsoJoJA6Kj" target="_blank" class="link"> <span>Featured Videos</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/glossary" target="_self" class="link" data-drupal-link-system-path="science-education/glossary"> <span>Glossary</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__primary-item">
|
||
|
||
<button type="button" class="usa-accordion__button usa-nav__link " aria-expanded="false" aria-controls="extended-mega-nav-section-5">
|
||
<span>News & Events </span>
|
||
</button>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div id="extended-mega-nav-section-5" class="usa-nav__submenu usa-megamenu" hidden="">
|
||
|
||
<div class="grid-row mm-container">
|
||
<div class="desktop:grid-col flex-auto duplicated-parent">
|
||
<div class="usa-nav__submenu-item">
|
||
<span><a href="/news-events" target="_self" class="link" data-drupal-link-system-path="node/156671">News & Events</a> <span class="uswds-arrow-forward"></span></span>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="grid-row mm-container">
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span target="_self" class="nolink"> <span class="usa-nav__submenu-heading">NEWS</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-1" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/news-events/newsroom" class="link" data-drupal-link-system-path="news-events/newsroom"> <span>Newsroom</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/news-events/press-releases" target="_self" class="link" data-drupal-link-system-path="news-events/press-releases"> <span>Press Releases</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/news-events/science-highlights" target="_self" class="link" data-drupal-link-system-path="news-events/science-highlights"> <span>Science Highlights</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/news-events/nibib-news" target="_self" class="link" data-drupal-link-system-path="news-events/nibib-news"> <span>NIBIB in the News</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span class="nolink"> <span class="usa-nav__submenu-heading">EVENTS</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-2" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/news-events/meetings-events/upcoming-events" class="link" data-drupal-link-system-path="news-events/meetings-events/upcoming-events"> <span>Upcoming Events</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/news-events/meetings-events/past-events" class="link" data-drupal-link-system-path="news-events/meetings-events/past-events"> <span>Past Events</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/news-events/meetings-events/photo-galleries" class="link" data-drupal-link-system-path="news-events/meetings-events/photo-galleries"> <span>Event Photos</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span target="_self" class="nolink"> <span class="usa-nav__submenu-heading">MEDIA RESOURCES</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-3" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/science-education/science-topics" target="_self" class="link" data-drupal-link-system-path="node/131271"> <span>Science Topics</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="mailto:nibibpress@mail.nih.gov" target="_self" class="link"> <span>Contact Us</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__primary-item">
|
||
|
||
<button type="button" class="usa-accordion__button usa-nav__link " aria-expanded="false" aria-controls="extended-mega-nav-section-6">
|
||
<span>About NIBIB </span>
|
||
</button>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div id="extended-mega-nav-section-6" class="usa-nav__submenu usa-megamenu" hidden="">
|
||
|
||
<div class="grid-row mm-container">
|
||
<div class="desktop:grid-col flex-auto duplicated-parent">
|
||
<div class="usa-nav__submenu-item">
|
||
<span><a href="/about-nibib" target="_self" class="link" data-drupal-link-system-path="node/156676">About NIBIB</a> <span class="uswds-arrow-forward"></span></span>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="grid-row mm-container">
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span target="_self" class="nolink"> <span class="usa-nav__submenu-heading">WHO WE ARE</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-1" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/about-nibib/mission" target="_self" class="link" data-drupal-link-system-path="node/79861"> <span>Mission & History</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/about-nibib/directors-corner" target="_self" class="link" data-drupal-link-system-path="node/121791"> <span>Director's Corner</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/about-nibib/organizational-chart" target="_self" class="link" data-drupal-link-system-path="node/18836"> <span>Organization Chart</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/about-nibib/advisory-council" target="_self" class="link" data-drupal-link-system-path="node/876"> <span>Advisory Council</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/about-nibib/careers-at-NIBIB" target="_self" class="link" data-drupal-link-system-path="node/131241"> <span>Jobs @ NIBIB</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="desktop:grid-col-4 submenu-list-container">
|
||
|
||
<div class="usa-nav__submenu-item">
|
||
<span target="_self" class="nolink"> <span class="usa-nav__submenu-heading">WHAT WE DO</span>
|
||
</span>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<ul id="basic-nav-section-2" class="usa-nav__submenu-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/about-nibib/strategic-plan" target="_self" class="link" data-drupal-link-system-path="node/11846"> <span>Strategic Plan</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
<li class="usa-nav__submenu-item">
|
||
|
||
|
||
|
||
|
||
<a href="/about-nibib/budget" target="_self" class="link" data-drupal-link-system-path="node/911"> <span>Budget</span>
|
||
</a>
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="usa-nav__secondary">
|
||
<div>
|
||
<section aria-label="search component" id="nibib-header-search" data-drupal-selector="search-block-form" role="search">
|
||
<form id="search-block-form" accept-charset="UTF-8" class="usa-search usa-search--small" role="search" action="/searching" method="get">
|
||
<label class="usa-sr-only" for="search-field-en-small">Search</label>
|
||
<input aria-label="Search" class="usa-input" id="edit-keys" data-drupal-selector="edit-keys" data-original-title="Enter the terms you wish to search for." data-toggle="tooltip" type="search" name="q" value="" tabindex="-1"/>
|
||
<button class="usa-button js-form-submit form-submit" name="search_btn" type="submit" value="Search" tabindex="-1">
|
||
<img src="/themes/custom/nibib/assets/uswds/img/usa-icons-bg/search--white.svg" class="usa-search__submit-icon" alt="Search" />
|
||
</button>
|
||
</form>
|
||
</section>
|
||
</div>
|
||
|
||
|
||
|
||
<ul class="header-nav__secondary-list">
|
||
<li class="header-nav__secondary-item">
|
||
<a href="/es/nibib-en-espanol"> En Español
|
||
</a>
|
||
</li>
|
||
<li class="header-nav__secondary-item">
|
||
<a target="_blank" class="link-list-serve" href="https://public.govdelivery.com/accounts/USNIBIB/subscriber/edit?preferences=true#tab1"> Join LISTSERV
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
</nav>
|
||
</header>
|
||
|
||
<main class="main-content usa-layout-docs usa-section " role="main" id="main-content">
|
||
<div class="grid-container">
|
||
<div class="grid-row breadcrumb-social-share-bar">
|
||
<div class="tablet:grid-col-6 desktop:grid-col-8">
|
||
<div>
|
||
|
||
<div id="block-breadcrumbs" class="block block-system block-system-breadcrumb-block">
|
||
|
||
|
||
<nav class="usa-breadcrumb--wrap" role="navigation" aria-label="breadcrumb">
|
||
<ol class="usa-breadcrumb__list">
|
||
<li class="usa-breadcrumb__list-item">
|
||
<a href="/" class="usa-breadcrumb__link"><span>Home</span></a>
|
||
</li>
|
||
<li class="usa-breadcrumb__list-item">
|
||
<a href="/news-events" class="usa-breadcrumb__link"><span>News & Events</span></a>
|
||
</li>
|
||
<li class="usa-breadcrumb__list-item">
|
||
<a href="/news-events/newsroom" class="usa-breadcrumb__link"><span>Newsroom</span></a>
|
||
</li>
|
||
</ol>
|
||
</nav>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
<div class="tablet:grid-col-6 desktop:grid-col-4">
|
||
<div>
|
||
|
||
<div id="block-addtoanysharebuttons" class="block block-addtoany block-addtoany-block">
|
||
|
||
|
||
<span class="a2a_kit a2a_kit_size_32 addtoany_list" data-a2a-url="https://www.nibib.nih.gov/news-events/newsroom/mri-contrast-agent-targets-hypoxic-disease" data-a2a-title="MRI contrast agent targets hypoxic disease"><a class="a2a_button_email"><span class="a2a_svg a2a_s_a2a a2a_s_email a2a-box"><img src="/themes/custom/nibib/assets/img/email-a2a.svg" border="0" alt="Facebook" width="27" height="27"></span></a><a class="a2a_button_facebook"><span class="a2a_svg a2a_s_a2a a2a_s_facebook a2a-box"><img src="/themes/custom/nibib/assets/img/facebook-a2a.svg" border="0" alt="Facebook" width="27" height="27"></span></a><a class="a2a_button_linkedin"><span class="a2a_svg a2a_s_a2a a2a_s_linkedin a2a-box"><img src="/themes/custom/nibib/assets/img/linkedin-a2a.svg" border="0" alt="Facebook" width="27" height="27"></span></a><a class="a2a_button_twitter"><span class="a2a_svg a2a_s_a2a a2a_s_x a2a-box"><img src="/themes/custom/nibib/assets/img/x-a2a.svg" border="0" alt="Facebook" width="27" height="27"></span
|
||
</a><a class="a2a_button_whatsapp"><span class="a2a_svg a2a_s_a2a a2a_s_whatsapp a2a-box"><img src="/themes/custom/nibib/assets/img/whatsapp-a2a.svg" border="0" alt="Facebook" width="27" height="27"></span></a><a class="a2a_dd addtoany_share"><span class="a2a_svg a2a_s_a2a a2a_s_share a2a-box"><img src="/themes/custom/nibib/assets/img/share-a2a.svg" border="0" alt="Share" width="27" height="27"></span></a></span>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="">
|
||
<div data-drupal-messages-fallback class="hidden"></div>
|
||
|
||
|
||
</div>
|
||
|
||
<div class="grid-row ">
|
||
|
||
</div>
|
||
|
||
<div class="grid-row grid-gap">
|
||
|
||
<div class="usa-layout-docs__main desktop:grid-col-fill">
|
||
|
||
<div id="block-nibib-page-title" class="block--page-title-block">
|
||
|
||
|
||
<h1 class="margin-0 page-header">
|
||
<span>MRI contrast agent targets hypoxic disease</span>
|
||
</h1>
|
||
|
||
</div>
|
||
|
||
<div id="block-nibib-content" class="block block-system block-system-main-block">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<article data-history-node-id="142226" about="/news-events/newsroom/mri-contrast-agent-targets-hypoxic-disease" class="news node node--type-news is-promoted full clearfix">
|
||
<div class="content">
|
||
<div class="grid-row">
|
||
<div class="grid-col flex-auto news--type-date"><strong>
|
||
|
||
<div class="field field--name-field-news-type field--type-entity-reference field--label-hidden field__item">Science Highlights</div>
|
||
</strong></div>
|
||
<div class="grid-col flex-auto news--type-date"><strong>
|
||
|
||
<div class="field field--name-field-publication-date field--type-datetime field--label-hidden field__item">March 22, 2023</div>
|
||
</strong></div>
|
||
</div>
|
||
<h3> Chemical cage is designed to shuttle probe to low-oxygen targets </h3>
|
||
|
||
<div id="node--news--more-from-author">
|
||
<h3>Media Contacts</h3>
|
||
<p>Jessica Meade<br/>
|
||
<a href="mailto:nibibpress@mail.nih.gov">nibibpress@mail.nih.gov</a><br/>
|
||
<a href="tel:301-496-3500">301-496-3500</a><br/>
|
||
<a href="/more-content-by/jessica-meade">More by this author</a></p>
|
||
</div>
|
||
|
||
|
||
<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Hypoxia, a lack of oxygen, is associated with numerous diseases including cancer, heart disease, arthritis, and diabetes. Certain tumors grow very rapidly in hypoxic environments and the ability to identify such tumors could be extremely useful for determining the best course of treatment. Using non-invasive magnetic resonance imaging (MRI) would be an ideal way to image such tumors but is a challenge because the standard contrast agents do not work well in hypoxic tissues with few blood vessels. Now researchers funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are developing new MRI contrast agents that are activated in low oxygen environments enabling improved diagnosis and treatment of hypoxic tumors as well as other diseases that have a hypoxic component. </p>
|
||
<p>For over 30 years contrast agents such as gadolinium have been used to obtain enhanced MRI images. The agents are made from a group of elements known as the rare-earth metals that have unique magnetic properties.</p>
|
||
<figure role="group" class="align-left">
|
||
<img alt="A computer generated image of a tumor with blood vessels and the words "imaging hypoxia"" data-entity-type="file" data-entity-uuid="173e9901-564f-4384-b2c0-20777200a8d7" height="255" src="/sites/default/files/inline-images/hypoxia%20580%20x%20320.jpg" width="464" loading="lazy"></p>
|
||
<figcaption>Artist’s rendition of decreasing oxygen levels moving from the periphery to the center of a solid tumor. Credit: adapted from S. A. Subasinghe et al., Biosensors 2022, 12(7), 478</figcaption>
|
||
</figure>
|
||
<p>Chemists at Wayne State University in collaboration with researchers at Baylor College of Medicine are using another rare-earth metal—europium (Eu)—to obtain enhanced MRI images of areas of hypoxic disease in the body. The team, led by Matthew J. Allen, Ph.D. professor and chair of the department of chemistry, have been working with Eu because it has the distinct property of creating a bright MRI signal in response to low oxygen levels. </p>
|
||
<p>The idea of using Eu as an MRI-enhancing agent, however, comes with an interesting twist. Although it gives a bright MRI signal in low-oxygen environments, if it contacts normal, higher oxygen levels it is inactivated. Because MRI contrast agents need to be shuttled through the circulatory system—in the highly oxygenated blood—Eu would be inactivated before reaching a low-oxygen target such as a tumor that grows rapidly in a low-oxygen environment. </p>
|
||
<p>“This is the type of problem biomedical engineers like to try to solve,” explains Tatjana Atanasijevic, PhD., manager of the program in molecular probes and imaging agents at NIBIB, which funded the work. “The Wayne State team is well suited to engineering a biochemical solution to shuttling Eu through the circulation to target tissues.” </p>
|
||
<p>Allen’s team set out to design a protective “chemical cage” that would surround the Eu in the circulation—fending off the oxygen, which has a relentless chemical “need” to interact with such compounds, and, in this case change the Eu structure to the irreversible inactive form. </p>
|
||
<p>They designed and synthesized a chemical library of 20 compounds with subtle variations in their structure which caused them to bind in chemically different ways to the Eu. </p>
|
||
<p>The Eu compounds were tested using MRI when added to an oxygen-rich solution. The compounds that were rapidly deactivated by oxygen would basically go dark on the MRI. However, one of the compounds, designated Eu-5 maintained the baseline MRI “glow” that is seen when the Eu has not been deactivated. </p>
|
||
<figure role="group" class="align-right">
|
||
<img alt="Image of the chemical structure of the Eu compound, it has a red Eu in the middle with black lines and atoms surrounding it" data-entity-type="file" data-entity-uuid="eb694cd8-a5de-4134-8094-34dc57932968" src="/sites/default/files/inline-images/Eu%205%20compound%20400%20x%20356.jpg" width="400" height="356" loading="lazy"></p>
|
||
<figcaption>Protective “molecular cage” surrounding an atom of europium. Credit: M.J Allen Wayne State University.</figcaption>
|
||
</figure>
|
||
<p>“The Eu-5 compound successfully fended-off the attacking oxygen in the solution,” explained Allen. “The MRI signal coming from Eu-5 gives us a clear indication that the chemical cage is successfully protecting Eu from being deactivated by oxygen.”</p>
|
||
<p>To test its effectiveness, researchers injected Eu-5 into the tail vein of a mouse where it was challenged to survive in the oxygen-rich blood. An MRI of the mouse after several minutes in the high oxygen environment indicated that the Eu remained intact—maintaining a persistent signal under MRI in the blood vessels. This result contrasted with the non-protective compounds that essentially went dark in the mouse experiment due to oxygen inactivation. </p>
|
||
<p>“Because it is so reactive, oxygen will inevitably break through chemical structures designed to keep it at bay,” said Allen. “What Eu-5 has accomplished is dramatically slowing the process, which would enable the compound to move through the blood to arrive at hypoxic tissue targets making it useful as an MRI probe to identify and monitor regions of low oxygen in tissues.”</p>
|
||
<p>The group is now in the process of more extensive testing of Eu-5 in mouse models of disease. A first test of Eu-5 will be its ability to travel successfully through the circulatory system of a mouse cancer experimental model and arrive at and enhance the MRI of hypoxic tumors. Because hypoxia in solid tumors is associated with poor prognosis and resistance to certain therapeutics, Eu-5 enhanced MRI images of hypoxic tumors could be an extremely valuable clinical tool for improved cancer treatment. </p>
|
||
<p>The work was reported in the Journal of the American Chemical Society<sup>1</sup>. This research was supported by grant R01EB027103 from the National Institute of Biomedical Imaging and Bioengineering, the National Cancer Institute, and the National Institute of General Medical Sciences. The authors acknowledge the use of the 9.4T MRI at the Small Animal Imaging Facility at Texas Children’s Hospital.</p>
|
||
<p>-<em>Written by Thomas Johnson, Ph.D.</em></p>
|
||
<p><br><br />
|
||
<a href="https://pubmed.ncbi.nlm.nih.gov/36475663/">Systemic Delivery of Divalent Europium from Ligand Screening with Implications to Direct Imaging of Hypoxia. Md Mamunur Rashid, Brooke A. Corbin, Pavan Jella, Caitlyn J. Ortiz, Md. Abul Hassan Samee, Robia G. Pautler, and Matthew J. Allen Journal of the American Chemical Society 2022 144 (50), 23053-23060 DOI: 10.1021/jacs.2c10373</a></p>
|
||
</div>
|
||
|
||
</div>
|
||
</article>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</main>
|
||
|
||
<footer class="usa-footer usa-footer--big">
|
||
<div class="usa-footer__primary-section">
|
||
<div class="grid-container pre-footer">
|
||
<div class="prefooter-row">
|
||
<div class="pre-footer-col">
|
||
<div>
|
||
<nav role="navigation" aria-labelledby="block-nibib-prefootermenu1-menu" id="block-nibib-prefootermenu1">
|
||
|
||
<h2 id="block-nibib-prefootermenu1-menu">Research</h2>
|
||
|
||
|
||
|
||
<ul class="menu menu--pre-footer-menu-1 nav">
|
||
<li class="first">
|
||
<a href="/programs/division-interdisciplinary-training-didt/debut" class="first" data-drupal-link-system-path="node/121961">DEBUT</a>
|
||
</li>
|
||
<li>
|
||
<a href="/funding/opportunities/all" data-drupal-link-system-path="funding/opportunities/all">Funding Opportunities</a>
|
||
</li>
|
||
<li>
|
||
<a href="/labs-at-nibib" data-drupal-link-system-path="node/156726">Labs@NIBIB</a>
|
||
</li>
|
||
<li class="last">
|
||
<a href="/programs/division-interdisciplinary-training-didt" class="last" data-drupal-link-system-path="node/47546">Training</a>
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
</nav>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
<div class="pre-footer-col">
|
||
<div>
|
||
<nav role="navigation" aria-labelledby="block-nibib-prefootermenu2-menu" id="block-nibib-prefootermenu2">
|
||
|
||
<h2 id="block-nibib-prefootermenu2-menu">EXPLORE</h2>
|
||
|
||
|
||
|
||
<ul class="menu menu--pre-footer-menu-2 nav">
|
||
<li class="first">
|
||
<a href="/news-events/newsroom" class="first" data-drupal-link-system-path="news-events/newsroom">Newsroom</a>
|
||
</li>
|
||
<li>
|
||
<a href="/news-events/meetings-events/upcoming-events" data-drupal-link-system-path="news-events/meetings-events/upcoming-events">Events</a>
|
||
</li>
|
||
<li>
|
||
<a href="/science-education" data-drupal-link-system-path="node/156666">Science Education</a>
|
||
</li>
|
||
<li class="last">
|
||
<a href="/about-nibib/strategic-plan" class="last" data-drupal-link-system-path="node/11846">Strategic Plan</a>
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
</nav>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
<div class="pre-footer-col">
|
||
<div>
|
||
<nav role="navigation" aria-labelledby="block-nibib-prefootermenu3-menu" id="block-nibib-prefootermenu3">
|
||
|
||
<h2 id="block-nibib-prefootermenu3-menu">SITE INFO</h2>
|
||
|
||
|
||
|
||
<ul class="menu menu--pre-footer-menu-3 nav">
|
||
<li class="first">
|
||
<a href="/disclaimer" class="first" data-drupal-link-system-path="node/18756">Disclaimer</a>
|
||
</li>
|
||
<li>
|
||
<a href="/policies" data-drupal-link-system-path="node/18761">Policies</a>
|
||
</li>
|
||
<li>
|
||
<a href="/sitemap" data-drupal-link-system-path="sitemap">Sitemap</a>
|
||
</li>
|
||
<li class="last">
|
||
<a href="/about-nibib/staff" class="last" data-drupal-link-system-path="about-nibib/staff">Staff Directory</a>
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
</nav>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
<div class="pre-footer-col">
|
||
<div>
|
||
|
||
<div id="block-nibib-listserv" class="block block-simple-block block-simple-blockprefooter-block-4">
|
||
|
||
<h2 class="block-title" >LISTSERV</h2>
|
||
|
||
<div class="usa-sign-up">
|
||
<form class="usa-form" accept-charset="UTF-8" action="https://public.govdelivery.com/accounts/USNIBIB/subscribers/qualify" id="GD-snippet-form" method="post">
|
||
<input name="utf8" type="hidden" value="✓">
|
||
<input name="authenticity_token" type="hidden" value="3VodVbPSwVMsPIIUJqtTROIeRmelSDuxCCzkKeiQhgJhy86M45yuIBHV3dt6P927jW7W5igGxTijSVid0BSqLQ=="> Get the latest NIBIB news and updates <label class="usa-sr-only" for="email">Email Address</label><br />
|
||
<input class="usa-input" id="email" name="email" placeholder="Email Address" type="text">
|
||
<input class="usa-button usa-button--secondary" name="commit" type="submit" value="Submit"> </p>
|
||
</form>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="footer-agency">
|
||
<div class="grid-container">
|
||
<div class="grid-row">
|
||
<div class="usa-footer__logo footer-agency--column">
|
||
<div class="mobile-lg:grid-col-auto">
|
||
<a href="https://nibib.nih.gov">
|
||
<img class="usa-footer__logo-img" src="/themes/custom/nibib/assets/img/NIBIB_Logo_Master_2024-footer.png" alt="Agency logo">
|
||
</a>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="footer-agency--column">
|
||
<div class="usa-footer__contact-links ">
|
||
<div class="usa-footer__contact-links-title">
|
||
<h5>STAY IN TOUCH</h5>
|
||
</div>
|
||
<div class="usa-footer__social-links grid-row grid-gap-1">
|
||
<div class="grid-col-auto">
|
||
<a class="usa-social-link usa-social-link--facebook" href="https://www.facebook.com/nibibgov">
|
||
<img class="usa-social-link__icon" src="/themes/custom/nibib/assets/uswds/img/usa-icons/facebook.svg" alt="Facebook">
|
||
</a>
|
||
</div>
|
||
|
||
<div class="grid-col-auto">
|
||
<a class="usa-social-link usa-social-link--twitter" href="https://twitter.com/nibibgov">
|
||
<img class="usa-social-link__icon" src="/themes/custom/nibib/assets/uswds/img/usa-icons/x.svg" alt="Twitter">
|
||
</a>
|
||
</div>
|
||
|
||
<div class="grid-col-auto">
|
||
<a class="usa-social-link usa-social-link--youtube" href="https://www.youtube.com/user/NIBIBTV">
|
||
<img class="usa-social-link__icon" src="/themes/custom/nibib/assets/uswds/img/usa-icons/youtube.svg" alt="YouTube">
|
||
</a>
|
||
</div>
|
||
|
||
<div class="grid-col-auto">
|
||
<a class="usa-social-link usa-social-link--linkedin" href="https://www.linkedin.com/company/national-institute-of-biomedical-imaging-and-bioengineering-nibib/">
|
||
<img class="usa-social-link__icon" src="/themes/custom/nibib/assets/uswds/img/usa-icons/linkedin.svg" alt="LinkedIn">
|
||
</a>
|
||
</div>
|
||
|
||
<div class="grid-col-auto">
|
||
<a class="usa-social-link usa-social-link--rss" href="https://www.nibib.nih.gov/rss-feeds">
|
||
<img class="usa-social-link__icon" src="/themes/custom/nibib/assets/uswds/img/usa-icons/rss_feed.svg" alt="RSS">
|
||
</a>
|
||
</div>
|
||
</div>
|
||
<div class="usa-footer__contact-links-contact">
|
||
<a href="/contact-us">Contact Us</a>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="usa-footer__secondary-section">
|
||
<div class="grid-container">
|
||
<div class="grid-row">
|
||
<div class="pre-footer-col-fill">
|
||
<p class="margin-0"><a href="/">nibib.nih.gov</a><br/><em>An official website of the <Span class="link-underlined"><a href="https://www.nih.gov">National Institutes of Health</a></span> and the <Span class="link-underlined"><a href="https://www.hhs.gov">Department of Health and Human Services</a></span></em></p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div class="grid-container">
|
||
<div class="grid-row bottom-footer-links">
|
||
|
||
<div class="tablet:grid-col-12">
|
||
<nav class="usa-footer__nav usa-identifier__container">
|
||
|
||
<div class="grid-row ">
|
||
|
||
|
||
|
||
|
||
|
||
<div class="mobile-lg:grid-col-6 desktop:grid-col-3 footer-menu-item">
|
||
<strong><a href="https://www.nih.gov/about-nih" class="link usa-footer_secondary-link">About NIH</a></strong>
|
||
<ul class="usa-list usa-list--unstyled">
|
||
</ul>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="mobile-lg:grid-col-6 desktop:grid-col-3 footer-menu-item">
|
||
<strong><a href="https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office" class="link usa-footer_secondary-link">FOIA requests</a></strong>
|
||
<ul class="usa-list usa-list--unstyled">
|
||
</ul>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="mobile-lg:grid-col-6 desktop:grid-col-3 footer-menu-item">
|
||
<strong><a href="https://oig.hhs.gov/" class="link usa-footer_secondary-link">Office of the Inspector General</a></strong>
|
||
<ul class="usa-list usa-list--unstyled">
|
||
</ul>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="mobile-lg:grid-col-6 desktop:grid-col-3 footer-menu-item">
|
||
<strong><a href="https://www.nih.gov/privacy-policy" class="link usa-footer_secondary-link">Privacy policy</a></strong>
|
||
<ul class="usa-list usa-list--unstyled">
|
||
</ul>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="mobile-lg:grid-col-6 desktop:grid-col-3 footer-menu-item">
|
||
<strong><a href="https://www.nih.gov/accessibility" class="link usa-footer_secondary-link">Accessibility statement</a></strong>
|
||
<ul class="usa-list usa-list--unstyled">
|
||
</ul>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="mobile-lg:grid-col-6 desktop:grid-col-3 footer-menu-item">
|
||
<strong><a href="https://www.edi.nih.gov/no-fear-act" class="link usa-footer_secondary-link">No FEAR Act data</a></strong>
|
||
<ul class="usa-list usa-list--unstyled">
|
||
</ul>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="mobile-lg:grid-col-6 desktop:grid-col-3 footer-menu-item">
|
||
<strong><a href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html" class="link usa-footer_secondary-link">Vulnerability Disclosure</a></strong>
|
||
<ul class="usa-list usa-list--unstyled">
|
||
</ul>
|
||
</div>
|
||
|
||
</div>
|
||
</nav>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
<div class="grid-container ">
|
||
<div class="grid-row">
|
||
<div class="pre-footer-col-fill">
|
||
<p class="margin-0">Looking for U.S. government information and services? <Span class="link-underlined"><a href="https://USA.gov">Visit USA.gov</a></span></p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</footer>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"","currentPath":"node\/142226","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"ajaxPageState":{"libraries":"eJyFUEFywzAI_JBqPYlBEnaIFdAInMS_r-24nRzS6UWzC4t2AUtxRVkjnmAYu4oHNCMHlitl1x6z2ZBnKrwR2Ajs0D6phB4GvjY6ZEJUNqqQCDrd9E7l01BDoQqvNy3uKnBn41Tpk7qTEfZ8gXGRwjJB5-niYFwIRn4epv97ekeWfVpb0-6LsDMZbHc4ltvjh4R53n9ybfENA2eVP5tXC7-nYikknqrmOb7hkLVTLH1pWIfCWHUa8IrPQE-vLPNP66Rh5Oq0xcbmvDkLJ07x2MlOMlVNWL8sd27vRTPs60kXexQLtprTbUtsFI4K7DCOHW_00D5_AzYa0e4","theme":"nibib","theme_token":null},"ajaxTrustedUrl":[],"back_to_top":{"back_to_top_button_trigger":100,"back_to_top_speed":1200,"back_to_top_prevent_on_mobile":true,"back_to_top_prevent_in_admin":false,"back_to_top_button_type":"image","back_to_top_button_text":"Scroll to top"},"data":{"extlink":{"extTarget":true,"extTargetAppendNewWindowLabel":"(opens in a new window)","extTargetNoOverride":false,"extNofollow":true,"extTitleNoOverride":false,"extNoreferrer":false,"extFollowNoOverride":false,"extClass":"ext","extLabel":"(link is external)","extImgClass":false,"extSubdomains":true,"extExclude":"(.)\\.gov\/(.)|(.)\\.gov","extInclude":"","extCssExclude":".social_media_share_icons, ul.we-mega-menu-ul, .path-research-funding .main-container.container .row .col-sm-12 .dynamic-layouts-container .dynamic-layout-row.rows_one_col_one_two .col_two_row_one:nth-child(2) section.block.block-block-content:nth-child(1), .path-taxonomy .main-container.container .row .col-sm-12 .dynamic-layouts-container .dynamic-layout-row.rows_one_col_one_two .col_two_row_one:nth-child(2) section.block.block-block-content:nth-child(1),\r\n.path-frontpage .main-container.container .region.region-content #block-nibib-homepage-slider.background-gradient\r\n.carousel.slide .carousel-indicators li","extCssInclude":"","extCssExplicit":"","extAlert":true,"extAlertText":"You are leaving the NIBIB website.\r\nThis external link provides additional information that is consistent with the intended purpose of this site. NIBIB cannot attest to the accuracy of a non-federal site. Linking to a non-federal site does not constitute an endorsement by NIBIB or any of its employees of the sponsors or the information and products presented on the site. \r\nYou will be subject to the destination site`s privacy policy when you follow the link.","extHideIcons":false,"mailtoClass":"mailto","telClass":"tel","mailtoLabel":"(link sends email)","telLabel":"(link is a phone number)","extUseFontAwesome":false,"extIconPlacement":"append","extPreventOrphan":false,"extFaLinkClasses":"fa fa-external-link","extFaMailtoClasses":"fa fa-envelope-o","extAdditionalLinkClasses":"","extAdditionalMailtoClasses":"","extAdditionalTelClasses":"","extFaTelClasses":"fa fa-phone","whitelistedDomains":[],"extExcludeNoreferrer":""}},"mediaelement":{"attachSitewide":0,"setDimensions":1},"user":{"uid":0,"permissionsHash":"5d02273f88884bb823a737a4f2b97e7e823a3c5950c86691a545715b47c2093d"}}</script>
|
||
<script src="/sites/default/files/js/js_zBFxPNXr1NS-kanX453YeOx3wxq1--Bx50GXYmPRzHk.js?scope=footer&delta=0&language=en&theme=nibib&include=eJxNiUEOwjAMBD8UkidVm7hUbq04sl3R_h4OQSDtYWYWRKHod8GE_DTtkSrasYR-NsofL7unprYWsnNAMjFEt4wdV1qvEO7H95qaOleuZROtkIc34xH-i-6we-rpL_I3FFQ4SA"></script>
|
||
<script src="https://static.addtoany.com/menu/page.js" defer></script>
|
||
<script src="/sites/default/files/js/js__GbrvRvcTy8JkqPPbsvklrpF4XgTLmWwxa_7yejIe4Q.js?scope=footer&delta=2&language=en&theme=nibib&include=eJxNiUEOwjAMBD8UkidVm7hUbq04sl3R_h4OQSDtYWYWRKHod8GE_DTtkSrasYR-NsofL7unprYWsnNAMjFEt4wdV1qvEO7H95qaOleuZROtkIc34xH-i-6we-rpL_I3FFQ4SA"></script>
|
||
|
||
</body>
|
||
</html>
|