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nih-gov/www.niaaa.nih.gov/about-niaaa/our-staff/mark-d-egli-phd
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Mark D. Egli, Ph.D.
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<p class="profile-item-title">Acting Director</p>
<h1 class="h2 profile-item-name">Mark D. Egli, Ph.D.</h1>
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Behavioral Science; Pain and alcohol interactions; Preclinical Therapeutics Discovery </div>
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</v:shape><![endif]--><!--[if !vml]--><!--[endif]--><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><o:p></o:p></span></p>
<p class="Default" style="margin-top:0in;line-height:normal"><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">Dr. Mark Egli is Director of the Division of Neuroscience and Behavior at the U.S. National Institutes of Health (NIH) National Institute on Alcohol Abuse and Alcoholism (NIAAA). He manages an extramural research grant portfolio, encompassing studies on the neural and behavioral aspects of Alcohol Use Disorder (AUD), as well as research on associated chronic pain conditions, cognitive impairment, and recovery processes. <o:p></o:p></span></span></p>
<p class="Default" style="margin-top:0in;line-height:normal"><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">Dr. Egli represents NIAAA on the </span></span><span class="Hyperlink0"><a href="https://heal.nih.gov"><span style="font-size:14.0pt;
color:black;mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:
90.197%;background:white"><span style="color:windowtext">NIH Helping to End Addiction Long-term</span></span><span lang="FR" style="font-size:14.0pt;
color:black;mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:
90.197%;background:white;mso-ansi-language:FR"><span style="color:windowtext">® </span></span><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">(HEAL) </span></span><span lang="FR" style="font-size:14.0pt;
color:black;mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:
90.197%;background:white;mso-ansi-language:FR"><span style="color:windowtext">Initiative</span></span></a></span><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">, contributing to funding opportunities for research on treatments for co-occurring AUD-OUD, and the influence of alcohol misuse on chronic pain. He provides expert advice to the </span></span><span class="Hyperlink0"><a href="https://pspp.ninds.nih.gov"><span style="font-size:14.0pt;color:black;
mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:90.197%;
background:white"><span style="color:windowtext">National Institute of Neurological Disorders and Stroke (NINDS) Preclinical Screening Platform for Pain (PSPP)</span></span></a></span><span style="font-size:14.0pt;color:black;
mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:90.197%;
background:white"><span style="color:windowtext"> program aligned with the HEAL goal of identifying and profiling non-addictive therapeutics for pain. Dr. Egli also represents NIAAA on the </span></span><span class="Hyperlink0"><a href="https://www.painconsortium.nih.gov"><span style="font-size:14.0pt;
color:black;mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:
90.197%;background:white"><span style="color:windowtext">NIH Pain Consortium</span></span></a></span><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">.<o:p></o:p></span></span></p>
<p class="Default" style="margin-top:0in;line-height:normal"><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">Dr. Egli launched the </span></span><span class="Hyperlink0"><a href="https://grants.nih.gov/grants/guide/notice-files/NOT-AA-19-021.html"><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">NIAAA Preclinical Medication Efficacy Testing Program </span></span></a></span><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">in 2007 and continues to promote discovery of therapeutic mechanisms for AUD. He represents NIAAA on the NIH Common Fund's </span></span><span class="Hyperlink0"><a href="https://commonfund.nih.gov/complementarie"><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">Complement Animal Research In Experimentation (Complement-ARIE) Program</span></span></a></span><span style="font-size:14.0pt;color:black;
mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:90.197%;
background:white"><span style="color:windowtext"> to promote lab or computer-based research approaches that more accurately model human biology, and complement or replace traditional research models.<o:p></o:p></span></span></p>
<p class="Default" style="margin-top:0in;line-height:normal"><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">Dr. Egli was a founding member and previous Chair of the NIH Program Leadership Committee, contributed to the </span></span><span class="Hyperlink0"><a href="https://orwh.od.nih.gov/e-learning/sex-as-biological-variable-primer"><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">NIH Sex as a Biological Variable</span></span></a></span><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext"> policy, and led recommendations for innovative scientific collaborations as part of the ongoing NIH COVID-19 Response Intra-Action Review. <o:p></o:p></span></span></p>
<p class="Default" style="margin-top:0in;line-height:normal"><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:
windowtext">Dr. Egli received his doctorate in psychology from the University of Minnesota with an emphasis on the e</span></span><span lang="PT" style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white;mso-ansi-language:PT"><span style="color:windowtext">xperimental </span></span><span style="font-size:14.0pt;
color:black;mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:
90.197%;background:white"><span style="color:windowtext">analysis of behavior and behavioral p</span></span><span lang="IT" style="font-size:14.0pt;color:black;
mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:90.197%;
background:white;mso-ansi-language:IT"><span style="color:windowtext">harmacology. </span></span><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:
black;mso-style-textfill-fill-alpha:90.197%;background:white"><span style="color:windowtext">He conducted research on environmental and genetic influences on behavior and cognition in people with intellectual disabilities at the Vanderbilt University Kennedy Center. He</span></span><span lang="FR" style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:90.197%;background:white;mso-ansi-language:FR"><span style="color:windowtext"> continue</span></span><span style="font-size:14.0pt;
color:black;mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:
90.197%;background:white"><span style="color:windowtext">s to be motivated by the profound impact NIH has on improving public health and seeks opportunities to expand research and policy in the behavioral and health sciences.<o:p></o:p></span></span></p>
</div>
</div>
<h3>Selected Publications</h3>
<div class="content-field">
<div><p class="Default" style="margin-top:0in;margin-right:0in;margin-bottom:6.0pt;
margin-left:0in;line-height:normal"><span lang="IT" style="font-size:14.0pt;
mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple;mso-ansi-language:IT"><span style="mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">Egli M</span></span><span style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">. (2018) Advancing pharmacotherapy development from preclinical a</span></span><span lang="ES-TRAD" style="font-size:14.0pt;mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple;mso-ansi-language:
ES-TRAD"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">nimal </span></span><span style="font-size:14.0pt;mso-style-textoutline-type:
none;mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">s</span></span><span lang="SV" style="font-size:14.0pt;mso-style-textoutline-type:
none;mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple;mso-ansi-language:
SV"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">tudies. In: Grant K., Lovinger D. (eds) </span></span><i><span style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">The Neuropharmacology of Alcohol. Handbook of Experimental Pharmacology</span></span></i><span lang="SV" style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
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solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple;mso-ansi-language:SV"><span style="mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">, 248:537-78</span></span><span style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">. </span></span><span class="Hyperlink1"><span style="color:black;
mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:100.0%"><a href="https://www.ncbi.nlm.nih.gov/pubmed/29374834"><span style="font-size:
14.0pt;color:black;mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:
100.0%;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple;font-weight:normal"><span style="color:black;mso-style-textfill-fill-color:
black;mso-style-textfill-fill-alpha:100.0%;mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">LINK</span></span></a></span></span><span style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><o:p></o:p></span></p>
<p class="Default" style="margin-top:0in;margin-right:0in;margin-bottom:6.0pt;
margin-left:0in;line-height:normal"><span class="None"><span lang="IT" style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple;mso-ansi-language:IT"><span style="mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">Guizzetti M, Davies DL, Egli M</span></span></span><span class="None"><span lang="SV" style="font-size:
14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple;mso-ansi-language:SV"><span style="mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">, Finn DA, Molina P, Regunathan S, Robinson DL, Sohrabji F. </span></span></span><span class="None"><span style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">(2016) Sex and the Lab: An a</span></span></span><span class="None"><span lang="ES-TRAD" style="font-size:14.0pt;mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple;mso-ansi-language:
ES-TRAD"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
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0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
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solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
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0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
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solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">sex in cell and animal</span></span></span><span class="None"><span style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
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simple;mso-ansi-language:ES-TRAD"><span style="mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
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0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple"> </span></span></span><span class="None"><span style="font-size:14.0pt;mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">s</span></span></span><span class="None"><span lang="SV" style="font-size:
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simple;mso-ansi-language:SV"><span style="mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">tudies. </span></span></span><span class="None"><i><span style="font-size:14.0pt;mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">Alcoholism: Experimental and Clinical Research,</span></span></i></span><span class="None"><span lang="SV" style="font-size:14.0pt;mso-style-textoutline-type:
none;mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple;mso-ansi-language:
SV"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"> 40(6):1182-91.</span></span></span><span class="None"><span lang="SV" style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"> </span></span></span><span class="Hyperlink1"><span style="color:black;
mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:100.0%"><a href="https://www.ncbi.nlm.nih.gov/pubmed/27154003"><span style="font-size:
14.0pt;color:black;mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:
100.0%;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple;font-weight:normal"><span style="color:black;mso-style-textfill-fill-color:
black;mso-style-textfill-fill-alpha:100.0%;mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">LINK</span></span></a></span></span><span style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
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solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><o:p></o:p></span></p>
<p class="Default" style="margin-top:0in;margin-right:0in;margin-bottom:6.0pt;
margin-left:0in;line-height:normal"><span class="None"><span lang="DE" style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple;mso-ansi-language:DE"><span style="mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">Suchankova P, Yan J, Schwandt ML, Stangl BL, Caparelli EC, Momenan R, Jerlhag E, Engel JA, Hodgkinson CA, </span></span></span><span class="None"><span lang="IT" style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple;mso-ansi-language:IT"><span style="mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">Egli M</span></span></span><span class="None"><span style="font-size:14.0pt;mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">, Lopez MF, Becker HC, Goldman D, Heilig M, Ramchandani VA, Leggio L. (2015) The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence. </span></span></span><span class="None"><i><span style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">Translational Psychiatry</span></span></i></span><span class="None"><span style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">. 2015 Jun 16;5:e583. doi: 10.1038/tp.2015.68</span></span></span><span class="None"><span lang="SV" style="font-size:14.0pt;mso-style-textoutline-type:
none;mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
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0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple;mso-ansi-language:
SV"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">.</span></span></span><span class="None"><span lang="SV" style="font-size:
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bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"> </span></span></span><span class="Hyperlink1"><span style="color:black;
mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:100.0%"><a href="https://www.ncbi.nlm.nih.gov/pubmed/26080318"><span style="font-size:
14.0pt;color:black;mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:
100.0%;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple;font-weight:normal"><span style="color:black;mso-style-textfill-fill-color:
black;mso-style-textfill-fill-alpha:100.0%;mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">LINK</span></span></a></span></span><span style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
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solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><o:p></o:p></span></p>
<p class="Default" style="margin-top:0in;margin-right:0in;margin-bottom:6.0pt;
margin-left:0in;line-height:normal"><span class="None"><span lang="IT" style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple;mso-ansi-language:IT"><span style="mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple">Egli M</span></span></span><span class="None"><span style="font-size:14.0pt;mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">, Koob GF, Edwards S (2012) Alcohol dependence as a chronic pain disorder. </span></span></span><span class="None"><i><span style="font-size:14.0pt;
mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">Neuroscience and Biobehavioral Reviews</span></span></i></span><span class="None"><span lang="SV" style="font-size:14.0pt;mso-style-textoutline-type:
none;mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple;mso-ansi-language:
SV"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">, 36:2179-92.</span></span></span><span class="None"><span lang="SV" style="font-size:14.0pt;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"><span style="mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple"> </span></span></span><span class="Hyperlink1"><span style="color:black;
mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:100.0%"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612891/"><span style="font-size:14.0pt;color:black;mso-style-textfill-fill-color:black;
mso-style-textfill-fill-alpha:100.0%;mso-style-textoutline-type:none;
mso-style-textoutline-outlinestyle-dpiwidth:0pt;mso-style-textoutline-outlinestyle-linecap:
round;mso-style-textoutline-outlinestyle-join:bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:
0%;mso-style-textoutline-outlinestyle-dash:solid;mso-style-textoutline-outlinestyle-align:
center;mso-style-textoutline-outlinestyle-compound:simple;font-weight:normal"><span style="color:black;mso-style-textfill-fill-color:black;mso-style-textfill-fill-alpha:
100.0%;mso-style-textoutline-type:none;mso-style-textoutline-outlinestyle-dpiwidth:
0pt;mso-style-textoutline-outlinestyle-linecap:round;mso-style-textoutline-outlinestyle-join:
bevel;mso-style-textoutline-outlinestyle-pctmiterlimit:0%;mso-style-textoutline-outlinestyle-dash:
solid;mso-style-textoutline-outlinestyle-align:center;mso-style-textoutline-outlinestyle-compound:
simple">LINK</span></span></a></span></span><o:p></o:p></p>
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