747 lines
38 KiB
Text
747 lines
38 KiB
Text
|
|
<!DOCTYPE html>
|
|
<html lang="en" dir="ltr">
|
|
<head>
|
|
<meta charset="utf-8" />
|
|
<meta name="description" content="About the image: Rod Bipolar Cells in the Retinal Circuitry." />
|
|
<meta name="google" content="vityevxlt8UuVFWvgz9_YwmJ5F0Nby_B3t54LLh-3Zw,lACaj571Gx_VdLF3HKSKUf1Wxx0H_bWxO3BYDZ_C1uw" />
|
|
<meta name="google-site-verification" content="vityevxlt8UuVFWvgz9_YwmJ5F0Nby_B3t54LLh-3Zw" />
|
|
<meta name="google-site-verification" content="lACaj571Gx_VdLF3HKSKUf1Wxx0H_bWxO3BYDZ_C1uw" />
|
|
<meta name="google-site-verification" content="UDfyeEAWNX_rJUHwog9j1kziEnByGwhkSJGLJclUWDA" />
|
|
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
|
|
<script type="application/ld+json">{
|
|
"@context": "https://schema.org",
|
|
"@graph": [
|
|
{
|
|
"@type": "WebPage",
|
|
"@id": "https://www.nei.nih.gov/research/research-labs-and-branches/photoreceptor-physiology-group",
|
|
"breadcrumb": {
|
|
"@type": "BreadcrumbList",
|
|
"itemListElement": [
|
|
{
|
|
"@type": "ListItem",
|
|
"position": 1,
|
|
"name": "Home",
|
|
"item": "https://www.nei.nih.gov/"
|
|
},
|
|
{
|
|
"@type": "ListItem",
|
|
"position": 2,
|
|
"name": "Research at NEI",
|
|
"item": "https://www.nei.nih.gov/research"
|
|
},
|
|
{
|
|
"@type": "ListItem",
|
|
"position": 3,
|
|
"name": "Research Labs and Branches",
|
|
"item": "https://www.nei.nih.gov/research/research-labs-and-branches"
|
|
},
|
|
{
|
|
"@type": "ListItem",
|
|
"position": 4,
|
|
"name": "Photoreceptor Physiology Group",
|
|
"item": "https://www.nei.nih.gov/research/research-labs-and-branches/photoreceptor-physiology-group"
|
|
}
|
|
]
|
|
},
|
|
"author": {
|
|
"@type": "GovernmentOrganization",
|
|
"@id": "https://www.nei.nih.gov",
|
|
"name": "National Eye Institute",
|
|
"url": "https://www.nei.nih.gov"
|
|
},
|
|
"publisher": {
|
|
"@type": "GovernmentOrganization",
|
|
"@id": "https://www.nei.nih.gov",
|
|
"name": "National Eye Institute",
|
|
"url": "https://www.nei.nih.gov"
|
|
}
|
|
}
|
|
]
|
|
}</script>
|
|
<link rel="icon" type="image/png" href="/themes/custom/nei/images/favicon.png" />
|
|
<link rel="apple-touch-icon" href="/themes/custom/nei/images/apple-touch-icon.png" />
|
|
<meta name="last-updated" content="Dec 18, 2024, 3:41:14 PM" />
|
|
<link rel="icon" href="/themes/custom/nei/favicon.ico" type="image/vnd.microsoft.icon" />
|
|
<link rel="alternate" hreflang="en" href="https://www.nei.nih.gov/research/research-labs-and-branches/photoreceptor-physiology-group" />
|
|
<link rel="canonical" href="https://www.nei.nih.gov/research/research-labs-and-branches/photoreceptor-physiology-group" />
|
|
<link rel="shortlink" href="https://www.nei.nih.gov/node/3773" />
|
|
|
|
<title>Photoreceptor Physiology Group | National Eye Institute</title>
|
|
<link rel="preload" href="/themes/custom/nei/fonts/Aleo-Bold.woff2" as="font" type="font/woff2" crossorigin>
|
|
<link rel="preload" href="/themes/custom/nei/fonts/Lato-Regular.woff2" as="font" type="font/woff2" crossorigin>
|
|
<link rel="stylesheet" media="all" href="/sites/default/files/css/css_PGSk_7b88hq2qr_--_38MLvoj1ffr9jv3JhnNJTnKUM.css?delta=0&language=en&theme=nei&include=eJw1ytEKgCAMRuEXsnwk-dMxrOliTqi3j4iuDnycfFCprpbyHK4tDb-FRvwSshrFYvOErNhxBUHnCaYEcbJ_61Qji26Q5ZXa-QH_YCJ9" />
|
|
<link rel="stylesheet" media="all" href="/themes/custom/nei/css/style.css?sraguf" />
|
|
|
|
<script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"","currentPath":"node\/3773","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","gtag":{"tagId":"","consentMode":false,"otherIds":[],"events":[],"additionalConfigInfo":[]},"suppressDeprecationErrors":true,"ajaxPageState":{"libraries":"eJxdjFsOwjAMBC8U6iNFbmKZgPNQ7BTK6SmgCsrPrndkTbhSTFa7D0OtZq-2Cil8yoWOj5WYYT8c18pC3pCBt_jfE17wfoTZCRYeyORRjPruLmhpIS-b2EvFmArD73CFErDUGeWkoadmekCb5fXVsCN3bGeF2EdDmb5kGqWNWZKeKTpd1SjDjEpuSXRTeOeUaxxCT9WYZ50","theme":"nei","theme_token":null},"ajaxTrustedUrl":{"form_action_p_pvdeGsVG5zNF_XLGPTvYSKCf43t8qZYSwcfZl2uzM":true},"gtm":{"tagId":null,"settings":{"data_layer":"dataLayer","include_classes":false,"allowlist_classes":"google\nnonGooglePixels\nnonGoogleScripts\nnonGoogleIframes","blocklist_classes":"customScripts\ncustomPixels","include_environment":false,"environment_id":"","environment_token":""},"tagIds":["GTM-TLVNS7W"]},"user":{"uid":0,"permissionsHash":"c48594e108b5c1c2bea409821b71477d5bc2724c8cae6d31f1d985af0daab85c"}}</script>
|
|
<script src="/sites/default/files/js/js_WgzMsgqb-MiW-Z2aLffGQHepZwX2hWrEHSrb46WqZrk.js?scope=header&delta=0&language=en&theme=nei&include=eJxdjEEOgCAMBD-E9kmkYrOpqdQAMerr5eBBvUx29jCp8HUKQOkZAe4wiY1B6Pj7yAsf33MNmZvuEq0nojnPmkFvCVmUYD6xDTUV3Vq9ATUbLxk"></script>
|
|
<script src="https://script.crazyegg.com/pages/scripts/0117/6571.js" async></script>
|
|
<script src="/modules/contrib/google_tag/js/gtag.js?sraguf"></script>
|
|
<script src="/modules/contrib/google_tag/js/gtm.js?sraguf"></script>
|
|
|
|
</head>
|
|
<body class="t-lab_page t-node__3773 path-research-research-labs-and-branches-photoreceptor-physiology-group">
|
|
<a href="#main-content" class="u-skip-link">
|
|
Skip to content
|
|
</a>
|
|
<noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-TLVNS7W"
|
|
height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>
|
|
|
|
<div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas>
|
|
|
|
<div id="u-page-outer" class="u-outer">
|
|
<div class="views-element-container site-notice-block" id="block-views-block-site-notices-block-1">
|
|
|
|
|
|
|
|
|
|
|
|
<div>
|
|
<div class="js-view-dom-id-bca3892fe522a94248c74087cbf8646ffbc018befc8d0e64978ba8c06dc01631 site-notices">
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
</div>
|
|
</div>
|
|
|
|
|
|
|
|
</div>
|
|
|
|
|
|
<img src="/themes/custom/nei/images/NEI-logo-tagline.svg" alt="" width="200" height="48" class="u-print-only">
|
|
<div class="r-global-header">
|
|
<div id="r-header-outer" class="r-header">
|
|
|
|
<div class="r-header-inner">
|
|
|
|
<div id="block-nei-branding" class="o-block--logo" role="banner">
|
|
|
|
|
|
|
|
|
|
|
|
<div class="o-logo">
|
|
<a href="/" class="o-logo__link" title="Home" rel="home"><span class="o-logo__text">National Eye Institute</span> <span class="o-logo__tagline">Research Today… Vision Tomorrow</span></a>
|
|
</div>
|
|
|
|
|
|
</div>
|
|
|
|
<div id="block-neimenubutton-2">
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
<div class="o-menu-toggle"><button class="o-menu-toggle__btn" id="menu-toggle__btn" aria-controls="block-mainnavigation" aria-expanded="true">Menu</button></div>
|
|
|
|
|
|
|
|
|
|
</div>
|
|
<div class="language-switcher-language-url has-no-translation" id="block-languageswitcher" role="navigation" aria-label="Language switcher">
|
|
|
|
|
|
<ul class="links">
|
|
<li class="is-active">
|
|
<a href="/research/research-labs-and-branches/photoreceptor-physiology-group" class="language-link is-active" lang="en" data-drupal-link-system-path="node/3773" aria-current="page">English</a>
|
|
</li>
|
|
<li>
|
|
<a href="/espanol/node/3773" class="language-link is-active" lang="es" data-drupal-link-system-path="node/3773" aria-current="page"> Español</a>
|
|
</li>
|
|
</ul>
|
|
|
|
|
|
</div>
|
|
<div class="search-global c-search--global" data-drupal-selector="search-global" id="block-globalsearchform" role="search">
|
|
|
|
|
|
|
|
|
|
|
|
|
|
<form action="/research/research-labs-and-branches/photoreceptor-physiology-group" method="post" id="search-global" accept-charset="UTF-8">
|
|
<div class="c-form__inner">
|
|
<div class="js-form-item form-item js-form-type-textfield form-item-global-terms js-form-item-global-terms">
|
|
<label for="edit-global-terms">Search the site</label>
|
|
<input data-drupal-selector="edit-global-terms" type="text" id="edit-global-terms" name="global-terms" value="" size="30" maxlength="128" placeholder="Search the site" class="form-text" />
|
|
|
|
</div>
|
|
<input data-drupal-selector="form-5lfiohy-ep-smnstpphbkj7zznkcvkhxitn2laan4ko" type="hidden" name="form_build_id" value="form-5LfIOHy-eP-sMNSTpPHbkj7zzNkcvkhXiTn2LaaN4ko" />
|
|
<input data-drupal-selector="edit-search-global" type="hidden" name="form_id" value="search_global" />
|
|
<div data-drupal-selector="edit-global-actions" class="form-actions js-form-wrapper form-wrapper" id="edit-global-actions"><input data-drupal-selector="edit-global-submit" type="submit" id="edit-global-submit" name="op" value="Search" class="button js-form-submit form-submit" />
|
|
</div>
|
|
|
|
</div>
|
|
</form>
|
|
|
|
|
|
|
|
|
|
|
|
</div>
|
|
|
|
</div>
|
|
|
|
</div>
|
|
|
|
<div class="r-menu-primary">
|
|
<nav aria-label="Main navigation" id="block-mainnavigation" class="o-menu-main__outer">
|
|
|
|
<ul class="o-menu o-menu-main"> <li class="o-menu-main__item o-menu-main__item--expanded o-menu-main__item--no-js"> <a href="/learn-about-eye-health" class="o-menu-main__link" data-drupal-link-system-path="node/39">Learn About Eye Health</a>
|
|
<ul class="o-menu o-menu-main__submenu"> <li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/learn-about-eye-health/healthy-vision" class="o-menu-main__link" data-drupal-link-system-path="node/788">Healthy Vision</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/learn-about-eye-health/eye-conditions-and-diseases" class="o-menu-main__link" data-drupal-link-system-path="learn-about-eye-health/eye-conditions-and-diseases">Eye Conditions and Diseases</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/learn-about-eye-health/eye-health-data-and-statistics" class="o-menu-main__link" data-drupal-link-system-path="node/825">Eye Health Data and Statistics</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/learn-about-eye-health/campaigns" class="o-menu-main__link" data-drupal-link-system-path="node/3859">Campaigns</a>
|
|
</li>
|
|
<li class="o-menu-main__item"> <a href="/learn-about-eye-health/vision-rehabilitation" class="o-menu-main__link" data-drupal-link-system-path="node/3865">Vision Rehabilitation</a>
|
|
</li>
|
|
<li class="o-menu-main__item"> <a href="/learn-about-eye-health/nei-for-kids" class="o-menu-main__link" data-drupal-link-system-path="node/162">NEI for Kids</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/learn-about-eye-health/outreach-resources" class="o-menu-main__link" data-drupal-link-system-path="node/125">Outreach Resources</a>
|
|
</li>
|
|
</ul>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--expanded o-menu-main__item--no-js"> <a href="/grants-and-training" class="o-menu-main__link" data-drupal-link-system-path="node/143">Grants and Training</a>
|
|
<ul class="o-menu-main__submenu o-menu"> <li class="o-menu-main__item"> <a href="/grants-and-training/how-apply" class="o-menu-main__link" data-drupal-link-system-path="node/145">How to Apply</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/grants-and-training/funding-opportunities" class="o-menu-main__link" data-drupal-link-system-path="node/144">Funding Opportunities</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/grants-and-training/training-nei" class="o-menu-main__link" data-drupal-link-system-path="node/146">Training at NEI</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/grants-and-training/funding-training-and-career-development" class="o-menu-main__link" data-drupal-link-system-path="node/152">Funding for Training and Career Development</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/grants-and-training/policies-and-procedures" class="o-menu-main__link" data-drupal-link-system-path="node/149">Policies and Procedures</a>
|
|
</li>
|
|
<li class="o-menu-main__item"> <a href="/grants-and-training/Prior-Approval-Requests" class="o-menu-main__link" data-drupal-link-system-path="node/3918">Prior Approval Requests</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/grants-and-training/resources-researchers" class="o-menu-main__link" data-drupal-link-system-path="node/150">Resources for Researchers</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/grants-and-training/contact-grants-and-funding-staff" class="o-menu-main__link" data-drupal-link-system-path="node/151">Contact Grants and Funding Staff</a>
|
|
</li>
|
|
</ul>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--expanded o-menu-main__item--no-js"> <a href="/research" class="o-menu-main__link" data-drupal-link-system-path="node/41">Research at NEI</a>
|
|
<ul class="o-menu-main__submenu o-menu"> <li class="o-menu-main__item"> <a href="/about/news-and-events/news" title="Research News" class="o-menu-main__link" data-drupal-link-system-path="about/news-and-events/news">Research News</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/research/clinical-trials" class="o-menu-main__link" data-drupal-link-system-path="node/132">Clinical Trials</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/research/research-labs-and-branches" class="o-menu-main__link" data-drupal-link-system-path="node/270">Research Labs and Branches</a>
|
|
</li>
|
|
<li class="o-menu-main__item"> <a href="/research/jobs-and-training-opportunities-nei" class="o-menu-main__link" data-drupal-link-system-path="node/564">Jobs and Training Opportunities at NEI</a>
|
|
</li>
|
|
<li class="o-menu-main__item"> <a href="/research/seminars" class="o-menu-main__link" data-drupal-link-system-path="node/4048">NEI Research Seminars</a>
|
|
</li>
|
|
</ul>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--expanded o-menu-main__item--no-js"> <a href="/about" class="o-menu-main__link" data-drupal-link-system-path="node/275">About NEI</a>
|
|
<ul class="o-menu-main__submenu o-menu"> <li class="o-menu-main__item"> <a href="/about/strategic-planning" class="o-menu-main__link" data-drupal-link-system-path="node/2857">Strategic Planning</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/about/news-and-events" class="o-menu-main__link" data-drupal-link-system-path="node/131">News and Events</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/about/goals-and-accomplishments" class="o-menu-main__link" data-drupal-link-system-path="node/281">Goals and Accomplishments</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/about/nei-history" class="o-menu-main__link" data-drupal-link-system-path="node/282">NEI History</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/about/nei-leadership" class="o-menu-main__link" data-drupal-link-system-path="node/415">NEI Leadership</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/about/budget-and-congress" class="o-menu-main__link" data-drupal-link-system-path="node/395">Budget and Congress</a>
|
|
</li>
|
|
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/about/advisory-committees" class="o-menu-main__link" data-drupal-link-system-path="node/285">Advisory Committees</a>
|
|
</li>
|
|
<li class="o-menu-main__item"> <a href="/learn-about-eye-health/outreach-resources/national-eye-health-education-program" title="National Eye Health Education Program" class="o-menu-main__link" data-drupal-link-system-path="node/265">National Eye Health Education Program</a>
|
|
</li>
|
|
<li class="o-menu-main__item"> <a href="/about/donate-nei" class="o-menu-main__link" data-drupal-link-system-path="node/286">Donate to NEI</a>
|
|
</li>
|
|
</ul>
|
|
</li>
|
|
</ul>
|
|
|
|
|
|
</nav>
|
|
|
|
|
|
</div>
|
|
</div>
|
|
|
|
<div class="o-overlay" aria-hidden="true"></div>
|
|
|
|
<div class="r-breadcrumb">
|
|
|
|
<div id="block-nei-breadcrumbs">
|
|
|
|
|
|
|
|
|
|
|
|
<nav aria-label="Breadcrumb">
|
|
<ol class="c-breadcrumb">
|
|
<li>
|
|
<a href="/">Home</a>
|
|
</li>
|
|
<li>
|
|
<a href="/research">Research at NEI</a>
|
|
</li>
|
|
<li>
|
|
<a href="/research/research-labs-and-branches">Research Labs and Branches</a>
|
|
</li>
|
|
<li>
|
|
Photoreceptor Physiology Group
|
|
</li>
|
|
</ol>
|
|
</nav>
|
|
|
|
|
|
|
|
</div>
|
|
|
|
|
|
</div>
|
|
|
|
|
|
|
|
<div class="r-page-header">
|
|
<div class="o-page-header">
|
|
|
|
<div id="block-nei-page-title">
|
|
|
|
|
|
|
|
|
|
|
|
|
|
<h1>
|
|
<span>Photoreceptor Physiology Group</span>
|
|
</h1>
|
|
|
|
|
|
|
|
|
|
</div>
|
|
|
|
|
|
|
|
|
|
</div>
|
|
</div>
|
|
|
|
<div class="r-highlighted">
|
|
<div data-drupal-messages-fallback class="hidden"></div>
|
|
|
|
|
|
</div>
|
|
|
|
<div class="r-help">
|
|
|
|
</div>
|
|
<main id="main-content" class="r-main">
|
|
<div class="r-pre-content">
|
|
|
|
</div>
|
|
|
|
<div class="r-splitter">
|
|
<div class="r-content">
|
|
|
|
<div id="block-nei-content">
|
|
|
|
|
|
|
|
|
|
|
|
<article data-history-node-id="3773">
|
|
<div>
|
|
<div class="r-content">
|
|
|
|
<img src="/sites/default/files/styles/large/public/2022-09/retinal-circuitry.jpg?itok=a8MiYreN" alt="Rod Bipolar Cells in the Retinal Circuitry" />
|
|
|
|
|
|
<div class="c-section">
|
|
<h2>About our work</h2>
|
|
<div>
|
|
<div><div class="c-text">
|
|
|
|
|
|
|
|
|
|
<p><em>About the image: Rod Bipolar Cells in the Retinal Circuitry.</em></p><p>The photoreceptors of the retina have been studied extensively over the past decades. However, much of the downstream processing from photoreceptors remains to be determined. Traditionally textbooks and review articles have argued that the function of the retina is to simply convey the visual stimulus to the brain, where complex computations can take place. However, the neural circuitry of the retina has a marvelous complexity consisting of ~130-140 clearly distinct cell types. How these cells process the visual information from the photoreceptors is a fascinating enigma and answering these questions will reveal fundamental mechanisms and strategies used in neural processing and sensory signaling.</p><p>We use comprehensive approach spanning from molecules to behavior and utilize a variety of very specific animal models. To answer our research questions, we use state-of-the art electrophysiological and behavioral experiments <em>combined</em> with molecular and genetic methods of the highest standard. Our experiments are performed on several unique genetically modified mouse lines that display altered photoresponses and signaling properties, as well as other species whose variations in retinal anatomy and physiology can further inform these questions. Thus, our research will greatly benefit our understanding of visual disorders such as Stationary Night Blindness, Retinal Degeneration and other impairments in low light level vision affecting the rod photoreceptors and their retinal circuitry. The long-term goal is to have a substantial impact on vision rescue therapies and artificial vision. Research methods will include single cell patch-clamp recordings, whole retina electroretinogram recordings and behavioral experiments.</p><h2>News from this lab</h2><ul><li><a href="https://www.nei.nih.gov/about/news-and-events/news/scientists-shine-light-how-eyes-adapt-dark">Scientists shine light on how eyes adapt to the dark</a></li><li><a href="https://www.nei.nih.gov/about/news-and-events/news/nih-researchers-decode-retinal-circuits-circadian-rhythm-pupillary-light-response">Photoreceptor cells in mice drive vision and non-vision functions using distinct circuits in the eye</a></li></ul>
|
|
|
|
|
|
</div>
|
|
</div>
|
|
</div>
|
|
</div>
|
|
|
|
|
|
<div class="c-section">
|
|
<h2>Selected publications</h2>
|
|
<div>
|
|
<div><div class="c-text">
|
|
|
|
|
|
|
|
|
|
<p>Bocchero U, Pahlberg J. <a href="https://pubmed.ncbi.nlm.nih.gov/37973380/">Origin of Discrete and Continuous Dark Noise in Rod Photoreceptors</a>. (2023) eNeuro 10(11): doi: 10.1523/ENEURO.0390-23.2023. PMID: 37973380; PMCID: PMC10687842.</p><p>Campla CK, Bocchero U, Strickland R, Nellissery J, Advani J, Ignatova I, Srivastava D, Aponte AM, Wang Y, Gumerson J, Martemyanov K, Artemyev NO, <strong>Pahlberg J</strong>*, Swaroop A* (2022)<br><a href="https://pubmed.ncbi.nlm.nih.gov/36180221/">Frmpd1 facilitates trafficking of G-protein transducin and modulates synaptic function in rod photoreceptors of mammalian retina</a>. eneuro:ENEURO.0348-0322.202</p><p>Corinne Beier*, Ulisse Bocchero*, Lior Levy, Zhijing Zhang, Nange Jin, Stephen Massey, Cristophe Ribelayga, Kirill Martemyanov, Samer Hattar, <strong>Johan Pahlberg</strong>. <a href="https://pubmed.ncbi.nlm.nih.gov/35767957/">Divergent outer retinal circuits drive image and non-image visual behaviors.</a> <em>Cell Reports </em>(2022) 39(13):111003.</p><h2><strong>Invited Peer-Reviewed Book chapters and Review Articles:</strong></h2><p>Johan Pahlberg, Anurima Majumder, Nikolai O. Artemyev. <a href="https://pubmed.ncbi.nlm.nih.gov/29564791/"><em><span>Ex vivo</span></em> functional evaluation of synaptic transmission from rods to rod bipolar cells in mice</a>. <em>In Methods in Molecular Biology: Mouse Retinal Phenotyping</em><span> (2018) 1753:203-216.</span></p><p>Johan Pahlberg, Alapakkam Sampath. The mitigation of transduction and synaptic noise in sensory systems is key to setting detection threshold. <em>Bioessays </em>(2011) 33(6): 438-477.</p>
|
|
|
|
|
|
</div>
|
|
</div>
|
|
<div>
|
|
<div class="c-image c-image--medium">
|
|
<div class="c-image__src">
|
|
<img src="https://www.nei.nih.gov/sites/default/files/styles/medium/public/2022-07/photoreceptor-physiology-group.jpg?itok=65qwfnZh" alt="Photoreceptor Physiology Group" width="900" height="786">
|
|
</div>
|
|
</div>
|
|
</div>
|
|
</div>
|
|
</div>
|
|
|
|
</div>
|
|
</div>
|
|
|
|
<div class="c-group__staff-list c-section" id="key-staff">
|
|
<h2>Photoreceptor Physiology Group key staff</h2>
|
|
<div class="views-element-container">
|
|
<div class="js-view-dom-id-752d57f7df8d9e72c8a8f1080a5153b5513ff162d8def359a7ce98f2dd927ba9 lab-staff">
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
<table class="cols-4">
|
|
<caption>
|
|
Key staff table
|
|
</caption>
|
|
<thead>
|
|
<tr>
|
|
<th id="view-title-table-column" class="views-field views-field-title" scope="col">Name</th>
|
|
<th id="view-field-lab-staff-title-table-column" class="views-field views-field-field-lab-staff-title" scope="col">Title</th>
|
|
<th id="view-field-email-table-column" class="views-field views-field-field-email" scope="col">Email</th>
|
|
<th id="view-field-phone-table-column" class="views-field views-field-field-phone" scope="col">Phone</th>
|
|
</tr>
|
|
</thead>
|
|
<tbody>
|
|
<tr>
|
|
<td headers="view-title-table-column" class="views-field views-field-title"><a href="/research/research-labs-and-branches/we-are-nei-intramural/ulisse-bocchero" hreflang="en">Ulisse Bocchero</a> </td>
|
|
<td headers="view-field-lab-staff-title-table-column" class="views-field views-field-field-lab-staff-title">Postdoctoral Fellow </td>
|
|
<td headers="view-field-email-table-column" class="views-field views-field-field-email"><a href="mailto:Ulisse.Bocchero@nih.gov">Ulisse.Bocchero@nih.gov</a> </td>
|
|
<td headers="view-field-phone-table-column" class="views-field views-field-field-phone"> </td>
|
|
</tr>
|
|
<tr>
|
|
<td headers="view-title-table-column" class="views-field views-field-title"><a href="/research/research-labs-and-branches/we-are-nei-intramural/edgar-cuapio-diaz" hreflang="en">Edgar Cuapio-Diaz</a> </td>
|
|
<td headers="view-field-lab-staff-title-table-column" class="views-field views-field-field-lab-staff-title">Postbac Fellow </td>
|
|
<td headers="view-field-email-table-column" class="views-field views-field-field-email"><a href="mailto:edgar.cuapo-diaz@nih.gov">edgar.cuapo-diaz@nih.gov</a> </td>
|
|
<td headers="view-field-phone-table-column" class="views-field views-field-field-phone"> </td>
|
|
</tr>
|
|
<tr>
|
|
<td headers="view-title-table-column" class="views-field views-field-title"><a href="/research/research-labs-and-branches/we-are-nei-intramural/irina-ignatova" hreflang="en">Irina Ignatova</a> </td>
|
|
<td headers="view-field-lab-staff-title-table-column" class="views-field views-field-field-lab-staff-title">Postdoctoral Fellow </td>
|
|
<td headers="view-field-email-table-column" class="views-field views-field-field-email"><a href="mailto:irina.ignatova@nih.gov">irina.ignatova@nih.gov</a> </td>
|
|
<td headers="view-field-phone-table-column" class="views-field views-field-field-phone"> </td>
|
|
</tr>
|
|
<tr>
|
|
<td headers="view-title-table-column" class="views-field views-field-title"><a href="/research/research-labs-and-branches/we-are-nei-intramural/johan-pahlberg" hreflang="en">Johan Pahlberg, Ph.D.</a> </td>
|
|
<td headers="view-field-lab-staff-title-table-column" class="views-field views-field-field-lab-staff-title">Senior Scientist </td>
|
|
<td headers="view-field-email-table-column" class="views-field views-field-field-email"><a href="mailto:johan.pahlberg@nih.gov">johan.pahlberg@nih.gov</a> </td>
|
|
<td headers="view-field-phone-table-column" class="views-field views-field-field-phone">(301) 451-1307 </td>
|
|
</tr>
|
|
</tbody>
|
|
</table>
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
</div>
|
|
</div>
|
|
|
|
</div>
|
|
|
|
<div class="c-group__staff-list c-section" id="alumni-staff">
|
|
<div class="views-element-container">
|
|
<div class="js-view-dom-id-89228c459258d7a2b52759d73ef7e0f882b5aed2df3dd89f96ec004c00e472fc lab-alumni">
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
</div>
|
|
</div>
|
|
|
|
</div>
|
|
|
|
</article>
|
|
|
|
|
|
|
|
</div>
|
|
|
|
|
|
|
|
<div id="block-researchatnei" class="c-callout c-callout--wide c-callout--rounded">
|
|
<figure class="c-callout__image">
|
|
<img src="/sites/default/files/styles/400px_square_crop/public/2019-04/shutterstock_605501567_333.jpg?itok=yofmpBZG" alt="">
|
|
</figure>
|
|
<div class="c-callout__content">
|
|
<h2 class="c-callout__heading">Research at NEI</h2>
|
|
|
|
|
|
|
|
|
|
<ul><li><a href="/research/research-labs-and-branches">Research Labs and Branches</a></li><li><a href="/research/research-labs-and-branches/we-are-nei-intramural">Principal Investigators</a></li><li><a href="/grants-and-training/training-nei">Training at NEI</a></li><li><a href="/about/news-and-events/news">Research News</a></li></ul>
|
|
|
|
|
|
</div>
|
|
</div>
|
|
|
|
<p class="views-element-container c-last-updated" id="block-views-block-nei-last-updated-block-1"><strong>Last updated:</strong> December 18, 2024</p>
|
|
|
|
|
|
</div>
|
|
<aside class="r-sidebar" role="complementary">
|
|
<div class="c-sidebar-widget">
|
|
<div class="c-chief">
|
|
<div class="c-chief__upper">
|
|
<div class="views-element-container">
|
|
<div class="o-table--sortable js-view-dom-id-e79dbdf371d87328bfe3dad19607022bd27920c0bab2dbe80cda7737676d6099 lab-staff">
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
<div class="views-row">
|
|
<div class="views-field views-field-field-lab-staff-headshot"><div class="field-content c-chief__image">
|
|
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2022-07/johan-pahlberg-bio-photo_0.jpg?itok=C7DyKMT2" width="200" height="200" alt="Johan Pahlberg, Ph.D., Principle Investigator" />
|
|
|
|
|
|
</div></div><div class="views-field views-field-view-node"><span class="field-content c-chief__bio"><p class="c-chief__title"><a href="/research/research-labs-and-branches/we-are-nei-intramural/johan-pahlberg" hreflang="en">Johan Pahlberg, Ph.D.</a></p>
|
|
<p></p>
|
|
<p class="c-chief__department-title">Senior Scientist</p>
|
|
<p class="c-chief__department-title"></p>
|
|
<p class="c-chief__email"><a href="mailto:johan.pahlberg@nih.gov">Email</a> </p>
|
|
<a href="/research/research-labs-and-branches/we-are-nei-intramural/johan-pahlberg" class="c-link__link">View bio</a></span></div></div>
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
</div>
|
|
</div>
|
|
|
|
</div>
|
|
</div>
|
|
<div class="c-sidebar-widget__contact-information">
|
|
<div class="c-sidebar-widget__header">
|
|
<h2 class="c-sidebar-widget__title">Contact <span>Information</span></h2>
|
|
</div>
|
|
<div class="views-element-container">
|
|
<div class="js-view-dom-id-d09c36122995e5258115adab481d646f7ef2e256b9501faf98d62704de807421 sidebar-address-labs">
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
<div>
|
|
<div class="c-sidebar-widget__contact-name">
|
|
|
|
<span>Photoreceptor Physiology Group</span>
|
|
|
|
</div>
|
|
|
|
<div class="c-sidebar-widget__contact-address">
|
|
Porter Neuroscience Research Center, Bldg 35<br>
|
|
|
|
|
|
|
|
|
|
35 Convent Dr., Room 3F-233
|
|
|
|
<br>
|
|
Bethesda,
|
|
Maryland
|
|
20892
|
|
</div>
|
|
|
|
<div class="c-sidebar-widget__contact-phone-fax">
|
|
|
|
|
|
<div>
|
|
<div><span>Phone:</span> (301) 451-1307</div>
|
|
</div>
|
|
|
|
|
|
</div>
|
|
</div>
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
</div>
|
|
</div>
|
|
|
|
<div class="c-sidebar-widget__contact-additional-info">
|
|
<a href="#key-staff" class="c-link__link">See additional lab contact information</a>
|
|
</div>
|
|
</div>
|
|
</div>
|
|
</aside>
|
|
</div>
|
|
</main>
|
|
|
|
<div class="r-footer">
|
|
<footer class="o-footer" role="contentinfo">
|
|
|
|
<div id="block-footer-2">
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
<div class="o-footer__row">
|
|
<div class="o-footer__group o-footer__group--logo"><a class="o-logo__link" href="/" rel="home" title="Home"><span class="o-logo__text">National Eye Institute</span></a>
|
|
<ul class="o-menu-social">
|
|
<li class="o-menu-social__item"><a class="o-menu-social__link o-menu-social__link--facebook outlink-ignore" href="https://www.facebook.com/NationalEyeInstitute">Facebook</a></li>
|
|
<li class="o-menu-social__item"><a class="o-menu-social__link o-menu-social__link--twitter outlink-ignore" href="https://twitter.com/NatEyeInstitute">Twitter</a></li>
|
|
<li class="o-menu-social__item"><a class="o-menu-social__link o-menu-social__link--linkedin outlink-ignore" href="https://www.linkedin.com/company/national-eye-institute-nei">LinkedIn</a></li>
|
|
<li class="o-menu-social__item"><a class="o-menu-social__link o-menu-social__link--youtube outlink-ignore" href="https://www.youtube.com/user/neinih">YouTube</a></li>
|
|
</ul>
|
|
|
|
<p> </p>
|
|
</div>
|
|
|
|
<div class="o-footer__group o-footer__group--contact">
|
|
<h2 class="o-footer__title">Contact NEI</h2>
|
|
|
|
<ul class="o-menu-footer">
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/contact-us/">Contact Us</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://www.nih.gov/about-nih/visitor-information">Visit NIH</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://list.nih.gov/cgi-bin/wa.exe?SUBED1=insidenei&A=1">Get Email Updates from NEI</a></li>
|
|
</ul>
|
|
</div>
|
|
|
|
<div class="o-footer__group o-footer__group--policies">
|
|
<h2 class="o-footer__title">Policies</h2>
|
|
|
|
<ul class="o-menu-footer">
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/accessibility-information">Accessibility</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://www.nih.gov/nondiscrimination-notice-language-assistance-services">Information in Other Languages</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/nei-website-privacy-policy">Privacy</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/freedom-information-act">Freedom of Information Act (FOIA)</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/disclaimers">Disclaimers</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/web-policies ">Web Policies</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html ">Vulnerability Disclosure</a></li>
|
|
</ul>
|
|
</div>
|
|
|
|
<div class="o-footer__group o-footer__group--employees">
|
|
<h2 class="o-footer__title">For NEI Employees</h2>
|
|
|
|
<ul class="o-menu-footer">
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://intranet.nei.nih.gov">Intranet</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://intranet.nei.nih.gov/hr/Pages/emergency.aspx">Emergency Information</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://ned.nih.gov/search/search.aspx">NIH Staff Directory</a></li>
|
|
</ul>
|
|
</div>
|
|
</div>
|
|
|
|
<div class="o-footer__row">
|
|
<div class="o-footer__full o-footer__full--parent">
|
|
<ul class="o-menu-footer o-menu-footer--swing">
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://www.nih.gov/">NIH.gov</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://hhs.gov/">HHS.gov</a></li>
|
|
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://usa.gov/">USA.gov</a></li>
|
|
</ul>
|
|
</div>
|
|
</div>
|
|
|
|
|
|
|
|
|
|
|
|
</div>
|
|
|
|
|
|
</footer>
|
|
</div>
|
|
|
|
</div>
|
|
|
|
</div>
|
|
|
|
|
|
|
|
<div class="c-lb-wrapper" id="lb-wrapper" aria-hidden="true">
|
|
<div class="c-lb-overlay" tabindex="-1"></div>
|
|
<div role="dialog" class="c-lb" id="lb">
|
|
<div class="c-lb-header">
|
|
<button class="c-lb-close-btn"><span class="c-lb-close-btn-text">Close</span><span class="c-lb-close-btn-text times" aria-hidden="true">×</span></button>
|
|
</div>
|
|
<figure class="c-lb-figure">
|
|
<figcaption class="c-lb-caption"></figcaption>
|
|
</figure>
|
|
</div>
|
|
</div>
|
|
|
|
<script src="/sites/default/files/js/js_agazM-qm5cOcplNZo9kNIWFtUrwt0V1xgAKtLyM44Us.js?scope=footer&delta=0&language=en&theme=nei&include=eJxdjEEOgCAMBD-E9kmkYrOpqdQAMerr5eBBvUx29jCp8HUKQOkZAe4wiY1B6Pj7yAsf33MNmZvuEq0nojnPmkFvCVmUYD6xDTUV3Vq9ATUbLxk"></script>
|
|
<script src="/themes/custom/nei/js/scripts.js?sraguf"></script>
|
|
|
|
</body>
|
|
</html>
|