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Report on anterior segment inflammation and immunity posted
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Report summarizes discussions form April 2021 meeting
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February 2, 2022
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<a href="/about/news-and-events/news?topic=405" hreflang="en">Immunology</a>
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<a href="/about/news-and-events/news?initiatives=415" hreflang="en">Anterior Segment Initiative</a>
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<p>NEI has published an executive summary from the April 23, 2021, virtual workshop “Immunity and Inflammation in the Anterior Segment of the Eye," hosted by the NEI Anterior Segment Initiative.</p>
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<p>Eye inflammation is the fifth leading cause of blindness in the U.S. with estimated costs similar to that of diabetic retinopathy. Host mechanisms that regulate immunity play a critical role in ocular inflammation, even in conditions not typically considered “immune-based,” since immunity regulates not just inflammation but also host tissue response to various stressors. These include diabetic retinopathy, age-related maculopathies, and glaucoma, among others. In 2019, the National Eye Institute (NEI) launched the <a href="/about/goals-and-accomplishments/nei-research-initiatives/anterior-segment-initiative">Anterior Segment Initiative</a> to better understand inflammation and its relationship with ocular pain, dry eye disease, the microbiome, and other eye conditions.</p><p>The workshop identified relevant gaps in knowledge, barriers to the development of new therapies, and promising areas for research exploration.
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<a href="/sites/default/files/2022-02/ASI_Wrksh_EC_Summary_2022-01-31_1800_508.pdf" class="c-link__link">Read the executive summary (PDF 400KB)</a>
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