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<p>The Advanced Research Projects Agency for Health (<a href="https://arpa-h.gov/">ARPA-H</a>), an agency within the U.S. Department of Health and Human Services (HHS), today announced the teams to receive awards from its Transplantation of Human Eye Allografts (<a href="https://arpa-h.gov/research-and-funding/programs/thea">THEA</a>) program. The agency’s commitment is up to $125 million, for a series of groundbreaking investments to develop the first-ever complete eye transplantation procedure and restore vision for the blind and visually impaired.</p><p>“This project’s goal—transplanting a functional human eye—is bold. Achieving it would be nothing short of remarkable and life-changing for people with major vision loss," said Kapil Bharti, Ph.D., NEI scientific director and a collaborator on one of the four newly funded project teams.</p><p>The teams are led by</p><ul><li>InGel Therapeutics in Allston, Mass. (TA 2), focusing on 3-D printed click-lock gel technology with micro-tunneled scaffolds containing stem cell-derived retinal cells.</li><li>Stanford University (TAs 1, 2, and 3), focusing on donor eye procurement, developing new strategies to promote survival and regeneration of the transplanted cells, and performing transplant surgeries. <a href="https://med.stanford.edu/ophthalmology/news-and-media/news-archive/2024-stories/vision-restoring-whole-eye-transplants-may-soon-be-a-reality.html">Stanford news story</a>.</li><li>The University of Colorado Anschutz Medical Campus (TAs 2 and 3), focusing on developing novel stem cell and bioelectronic technologies to promote nerve regeneration and performing transplant surgeries. <a href="https://news.cuanschutz.edu/news-stories/university-of-colorado-anschutz-medical-campus-led-team-receives-up-to-46-million-to-develop-innovative-treatment-to-cure-blindness">U. Colorado news story</a>.</li><li>The University of Miami Bascom Palmer Eye Institute (TA 1), focusing on donor eye procurement and preservation outside the body with its eye-ECMOTM device. <a href="https://news.med.miami.edu/bascom-palmer-receives-multimillion-dollar-award-to-support-whole-eye-transplant/">U. Miami news story</a>.</li></ul><p><a href="https://arpa-h.gov/news-and-events/arpa-h-announces-pioneering-investments-restore-vision-people-who-are-blind">ARPA-H announcement</a></p>
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