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<a href="mailto:farran.briggs@nih.gov" target="_blank">Email</a>
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</span>
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<span class="c-contact__label c-contact__phone">
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301-480-2764
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<span>Building 49, Room 240</span>
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<span>49 Convent Drive</span>
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<span>Bethesda, </span>
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<span>
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Maryland
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<span>
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20892-4435
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<div class="c-section">
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<h2>Biography</h2>
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<div><p>Dr. Briggs received her bachelor’s degree in biology from Dartmouth College and then completed her PhD in biology at the University of California, San Diego working in the lab of Dr. Ed Callaway at the Salk Institute. Her postdoctoral training at the University of California, Davis under the mentorship of Dr. Marty Usrey, along with Drs. Barbara Chapman and Ron Mangun, was supported by an NRSA fellowship and then a Pathway to Independence Award (K99), both from the NEI. She established her independent laboratory first at the Geisel School of Medicine at Dartmouth and then became a tenured Associate Professor in Neuroscience and Brain and Cognitive Sciences at the University of Rochester. Her independent lab has been funded by the NIH, the National Science Foundation, and the Whitehall Foundation. In 2024, Dr. Briggs joined the NEI as a Senior Investigator and she is also a 2024 NIH Distinguished Scholar. She holds an Adjunct Professor position at the University of Rochester and an adjunct appointment with the National Institute of Mental Health (NIMH).</p></div>
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</div>
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<div class="c-section">
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<h2>Current research</h2>
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<div><p>The goal of our laboratory is to investigate how neuronal circuits in the early visual system encode and process visual information in healthy and disease states, and to understand how visual attention modulates these activities. Our research consistently links structure and function, e.g. exploring how particular cell types are wired together to establish specific components of visual perception. Current efforts focus on measuring and manipulating identified circuits in behaving subjects to assess neuronal contributions to active vision. The lab utilizes a combination of experimental methods including electrophysiology, optogenetics, and imaging in subjects performing visual discrimination tasks in conjunction with neuroanatomical and computational analysis approaches.</p><p>Current research questions include:</p><ol><li>How do reciprocal circuits connecting the visual thalamus and visual cortex contribute to visual discrimination and attention?</li><li>How does activity in thalamo-cortico-thalamic circuits mediate training-induced vision recovery following visual cortical stroke?</li><li>What alterations in retino-thalamo-cortical circuit structure and function generate visual deficits observed in schizophrenia?</li><li>How do early visual circuits incorporate contextual information during active, natural vision?</li></ol><p>At the core of our research is a commitment to honing and applying novel technologies to advance our understanding of neuronal structure and function. We continue to pursue novel methodological approaches, including chronically implantable dense multielectrode arrays, strategies for optimal circuit manipulation, and methods for unrestrained, natural vision studies performed in the laboratory. These efforts enable us to continue pushing the boundaries of what is possible in systems neuroscience to further our understanding of visual system structure and function in health and disease.</p></div>
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</div>
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<div class="c-section">
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<h2>Selected publications</h2>
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<div>
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<div><div class="c-text">
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<ol><li>Shah, S., Hembrook-Short, J., Mock, V., Briggs, F. (2024) <a href="https://pubmed.ncbi.nlm.nih.gov/39172780/">Correlated variability, and its attentional modulation, depend on anatomical connectivity</a>. <em>PNAS</em>: 121(35): 1-11 doi:10.1073/pnas.2318841121<br> </li><li>Adusei, M., Callaway, E.M., Usrey, W.M., Briggs, F. (2024) <a href="https://pubmed.ncbi.nlm.nih.gov/38479809/">Parallel streams of direct corticogeniculate feedback from mid-level extrastriate cortex in the macaque monkey</a>. <em>eNeuro</em>: 11(3): 1-15 doi:10.1523/eneuro.0364-23.2024<br> </li><li>Hu, W., Zhu, S., Briggs, F., Doyley, M. (2023) <a href="https://pubmed.ncbi.nlm.nih.gov/36681137/">Functional ultrasound imaging reveals 3D structure of orientation domains in ferret primary visual cortex</a>. <em>NeuroImage</em> 268: 119889<br> </li><li>Murphy, A.J., Shaw, L., Hasse, J.M., Goris, R.L.T., Briggs, F. (2021) <a href="https://pubmed.ncbi.nlm.nih.gov/32632511/">Optogenetic activation of corticogeniculate feedback stabilizes response gain and increases information coding in LGN neurons.<em> </em></a><em>J. Computational Neuroscience</em> 49(3): 259-271<br> </li><li>Hembrook-Short, J.R., Mock, V.L., Usrey, W.M., Briggs, F. (2019) <a href="https://pubmed.ncbi.nlm.nih.gov/30541911/">Attention enhances the efficacy of communication in V1 local circuits</a>. <em>J. Neuroscience</em> 39: 1066-1076</li><li>Mock, V.L., Luke, K.L., Hembrook-Short, J.R., Briggs, F. (2018) <a href="https://pubmed.ncbi.nlm.nih.gov/29975169/">Dynamic communication of attention signals between LGN and V1</a>. <em>J. Neurophysiology</em> 120(4): 1625-1639</li><li>Hasse, J.M. & Briggs, F. (2017) <a href="https://pubmed.ncbi.nlm.nih.gov/28698363/">Corticogeniculate feedback sharpens the temporal precision and spatial resolution of visual signals in the ferret</a>. <em>PNAS</em> 114(30): E6222-E6230</li><li>Hembrook-Short, J.R., Mock, V.L., Briggs, F. (2017) <a href="https://pubmed.ncbi.nlm.nih.gov/28648826/">Attentional modulation of neuronal activity depends on neuronal feature selectivity</a>. <em>Current Biology</em> 27(13): 1878-1887</li></ol>
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</div>
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</article>
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<p class="views-element-container c-last-updated" id="block-views-block-nei-last-updated-block-1"><strong>Actualización más reciente:</strong> 17 de enero de 2025</p>
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