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April 18, 2023
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<p>Muna Naash, and colleagues, designed and generated a model expressing the most common human disease mutation in Usher syndrome type 2A, an inherited disorder that causes deafness and blindness.</p>
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<img src="https://www.nei.nih.gov/sites/default/files/styles/small/public/2023-04/Muna%20Naash.jpg?itok=UZPMHWEy" alt="Muna Nash" width="360" height="450">
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<p>Muna Naash, Ph.D., John S. Dunn Endowed Professor, University of Houston.</p>
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<p>Most Usher syndrome models successfully reproduce the hearing loss observed in patients but fail to model the visual problems. Also, no study has come close to examining the actual mechanics behind the illness, until now – even though establishing a model for USH2A that mirrors patient’s phenotypes has been an important goal for the future development of therapeutic strategies.</p>
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