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<div class="c-section">
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<h2>Biography</h2>
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<div><p>HaoHua Qian, Ph.D., is currently the head of the Visual Function Core at NEI. Prior to joining NEI in 2010, he was an Associate Professor of Neuroscience in the Department of Ophthalmology of Visual Sciences at the University of Illinois in Chicago. Before joining the University of Illinois, he was a postdoctoral fellow in the laboratory of Dr. John Dowling in the department of Molecular and Cellular Biology at Harvard University. In 1993, he was awarded a Grass Fellowship in Neurophysiology at the Marine Biological Laboratory in Woods Hole. He earned his Ph.D in Anatomy and Cell Biology at the University of Illinois at Chicago. Before that, he earned a Master’s degree in Neurobiology at the Shanghai Institute of Physiology, and a Bachelor’s degree in Biology at Nanjing University in China.</p></div>
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<div class="c-section">
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<h2>Current research</h2>
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<div><p>We are currently developing and testing novel techniques to evaluate visual function and performance in animal models. We are particularly interested in non-invasive recording methods that could allow us to follow vision of the animal over the time. We are focused on a combination of tools such as electrophysiological recordings, retinal and fundus imagining, and behavior tests that could provide complementary information about integrity and function at different stages of visual signal pathways.</p></div>
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<div class="c-section">
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<h2>Selected publications</h2>
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<div><div class="c-text">
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<ol><li>HeungSun KWon, Karl Kevala, Haohua Qian, Mones Abu-Asab, Samarjit Patnaik, Juan Marugan, Hee-Yong Kim <a href="https://pubmed.ncbi.nlm.nih.gov/36982411/">Targeting GPR110 to Improve Visual Function Impaired by Optic Nerve Injury</a>. Int J Mol Sci. 2023 Mar 10;24(6):5340. doi: 10.3390/ijms24065340.</li><li>Berkowitz BA, Podolsky RH, Childers KL, Burgoyne T, De Rossi G, Qian H, Roberts R, Katz R, Waseem R, Goodman C (2022) <a href="https://pubmed.ncbi.nlm.nih.gov/35816042/">Functional Changes Within the Rod Inner Segment Ellipsoid in Wildtype Mice: An Optical Coherence Tomography and Electron Microscopy Study</a>. Invest. Ophthal. Vis. Sci. 63(8):8. doi: 10.1167/iovs.63.8.8.PMID: 35816042 ; PMCID: PMC9284466.</li><li>Shasha Gao, Yong Zeng, Yichao Li, Ethan D. Cohen, Bruce A. Berkowitz and Haohua Qian (2022) <a href="https://pubmed.ncbi.nlm.nih.gov/36338188/">Fast and slow light-induced changes in murine outer retina OCT: Complimentary high spatial resolution functional biomarkers</a>. PNAS Nexus 2022 Oct 14;1(4):pgac208. doi: 10.1093/pnasnexus/pgac208. PMID: 36338188; PMCID: PMC9615127.</li><li>Ma Z, Jiao X, Agbaga MP, Anderson RE, Qian H, Li Q, Dong L, Hejtmancik JF. <a href="https://pubmed.ncbi.nlm.nih.gov/36361898/">A Bietti Crystalline Dystrophy Mouse Model Shows Increased Sensitivity to Light-Induced Injury</a>. Int J Mol Sci. 2022 Oct 28;23(21):13108. doi: 10.3390/ijms232113108. PMID: 36361898; PMCID: PMC9658898.</li><li>Berkowitz BA, Podolsky RH, Childers KL, Roberts R, Katz R, Waseem R, Robbings BM, Hass DT, Hurley JB, Sweet IR, Goodman C, Qian H, Alvisio B, Heaps S. <a href="https://pubmed.ncbi.nlm.nih.gov/36576748/">Transducin-Deficient Rod Photoreceptors Evaluated With Optical Coherence Tomography and Oxygen Consumption Rate Energy Biomarkers</a>. Invest Ophthalmol Vis Sci. 2022 Dec 1;63(13):22. doi: 10.1167/iovs.63.13.22. PMID: 36576748; PMCID: PMC9804021.</li><li>Shasha Gao, Yichao Li, David Bissig, Ethan D. Cohen, Robert H. Podolsky, Karen Lins Childers, Gregory Vernon, Sonia Chen, Bruce A. Berkowitz and Haohua Qian (2021) <a href="https://pubmed.ncbi.nlm.nih.gov/35577893/">Functional regulation of an outer retina hyporeflective band on optical coherence tomography images</a>. Scientific Reports 2021 May 13;11(1):10260. doi: 10.1038/s41598-021-89599-1. PMID: 33986362</li><li>Zeng Y, Qian H, Campos MM, Li Y, Vijayasarathy C, Sieving PA. (2021) <a href="https://pubmed.ncbi.nlm.nih.gov/34548657/">Rs1h-/y exon 3-del rat model of X-linked retinoschisis with early onset and rapid phenotype is rescued by RS1 supplementation</a>. Gene Ther. 2021 Sep 22. doi: 10.1038/s41434-021-00290-6. Epub ahead of print. PMID: 34548657; PMCID: PMC8938309.</li><li>Yichao Li, Ethan D. Cohen, Haohua Qian (2020) <a href="https://pubmed.ncbi.nlm.nih.gov/33100974/">Rod and cone coupling modulates photopic ERG responses in mouse retina</a>. Front. Cell. Neurosci. 2020 Sep 25;14:566712. doi: 10.3389/fncel.2020.566712. PMID: 33100974; PMCID: PMC7546330.</li><li>Yichao Li, Yikui Zhang, Sonia Chen, Gregory Vernon, Wai T. Wong, and Haohua Qian (2018) <a href="https://pubmed.ncbi.nlm.nih.gov/29490345/">Light-Dependent OCT Structure Changes in Photoreceptor Degenerative rd 10 Mouse Retina</a>. Invest. Ophthal. Vis. Sci. 59: 1084–1094.</li><li>Yichao Li, Robert N. Fariss, Jennifer W. Qian, Ethan D. Cohen, Haohua Qian (2016) <a href="https://pubmed.ncbi.nlm.nih.gov/27409460/">Light-induced thickening of photoreceptor outer segment layer detected by ultra-high resolution OCT imaging</a>. Invest. Ophthal. Vis. Sci. 57:OCT105– OCT111.</li></ol>
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<a href="https://pubmed.ncbi.nlm.nih.gov/?term=Haohua%20Qian%5BAuthor%5D">PubMed search for Haohua Qian</a>
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</article>
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<p class="views-element-container c-last-updated" id="block-views-block-nei-last-updated-block-1"><strong>Actualización más reciente:</strong> 9 de agosto de 2024</p>
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