935 lines
52 KiB
Text
935 lines
52 KiB
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<div> <p>Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.</p>
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<select data-drupal-selector="edit-topic" id="edit-topic" name="topic" class="form-select"><option value="All">- Any -</option><option value="3">About NEI</option><option value="246">Age-Related Macular Degeneration</option><option value="389">Aging</option><option value="390">Albinism</option><option value="237">Amblyopia (Lazy Eye) </option><option value="391">Announcements</option><option value="365">AREDS/AREDS2</option><option value="392">Artificial Intelligence</option><option value="52">Astigmatism</option><option value="107">Bietti's Crystalline Dystrophy</option><option value="393">Bioinformatics</option><option value="108">Blepharitis</option><option value="167">Blindness</option><option value="394">Cancer</option><option value="238">Cataracts</option><option value="433">Central Retinal Vein Occlusion (CRVO) </option><option value="384">Cerebral Visual Impairment (CVI)</option><option value="395">Children</option><option value="109">Coloboma</option><option value="239">Color Blindness</option><option value="396">Contact Lenses</option><option value="363">Convergence Insufficiency</option><option value="397">Cornea</option><option value="243">Corneal Conditions</option><option value="398">Devices</option><option value="13">Diabetic Eye Disease</option><option value="240">Dry Eye</option><option value="103">Education Programs</option><option value="399">Epidemiology</option><option value="400">Eye Safety</option><option value="386">Farsightedness (Hyperopia)</option><option value="134">Floaters</option><option value="401" selected="selected">Gene Therapy</option><option value="402">Genetics</option><option value="12">Glaucoma</option><option value="403">Health Disparities</option><option value="44">Healthy Vision</option><option value="404">Imaging</option><option value="405">Immunology</option><option value="350">Infectious Disease</option><option value="112">Keratoconus</option><option value="55">Leber Congenital Amaurosis</option><option value="406">Lens</option><option value="42">Macular Edema</option><option value="137">Microphthalmia</option><option value="48">Myopia</option><option value="385">Nearsightedness (Myopia)</option><option value="349">Neuroscience</option><option value="407">Nutrition & Lifestyle</option><option value="8">Optic Nerve Disorders</option><option value="130">Pink Eye</option><option value="387">Presbyopia</option><option value="409">Public Health</option><option value="56">Rare Diseases</option><option value="244">Refractive Errors</option><option value="364">Regenerative Medicine</option><option value="7">Retina</option><option value="57">Retinitis Pigmentosa</option><option value="150">Retinoblastoma</option><option value="119">Retinopathy of Prematurity</option><option value="410">Small Business</option><option value="151">Stargardt Disease</option><option value="41">Stem Cells</option><option value="411">Strabismus</option><option value="412">Training</option><option value="152">Usher Syndrome</option><option value="58">Uveitis</option><option value="241">Vision Rehabilitation</option><option value="413">Visual Processing</option><option value="414">Women's Eye and Vision Health</option></select>
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<a href="/about/news-and-events/news?topic=All#block-nei-content" class="c-filter__pill">Gene Therapy</a><a href="/about/news-and-events/news#block-nei-content" class="c-filter__pill--clear">Clear all filters</a>
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53 items
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<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2024-12/optic-nerves-998x665.jpg?itok=xeekyoXZ" width="200" height="200" alt="optic nerves" />
|
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<a class="c-teaser__link" href="/about/news-and-events/news/nerve-regrowth-sight">
|
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Nerve regrowth in sight
|
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</a>
|
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</h2>
|
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<p class="c-teaser__date">
|
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<time datetime="2024-12-05T14:50:42-05:00">December 5, 2024</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
UConn scientists led by Ephraim Trakhtenberg regrew optic nerves in mice through eye injections of fibronectin peptides (pieces of the larger protein).
|
||
</div>
|
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</div>
|
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</div></div></div>
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<div class="c-sidebar-widget__list-item views-row">
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<div class="c-teaser__image">
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<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2024-11/layers%20of%20retina.jpeg?itok=l95gwxMc" width="200" height="200" alt="" />
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<div class="c-teaser__content">
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<h2 class="c-teaser__header">
|
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<a class="c-teaser__link" href="/about/news-and-events/news/crispr-gene-editing-promising-blinding-disease-retinitis-pigmentosa">
|
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CRISPR gene editing promising for blinding disease retinitis pigmentosa
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2024-11-27T09:25:51-05:00">November 27, 2024</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
National Eye Institute-funded scientists using gene editing corrected a mutation in a mouse model of retinitis pigmentosa, an inherited blinding eye disorder. The gene editing strategy restored production of rhodopsin, and retinal function and structure
|
||
</div>
|
||
</div>
|
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</div></div></div>
|
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<div class="c-sidebar-widget__list-item views-row">
|
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<div class="field-content"><div class="c-teaser">
|
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<div class="c-teaser__image">
|
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|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/LCA_disorder.jpg?itok=pO9qcOct" width="200" height="200" alt="LCA is an inherited disorder that causes vision loss in childhood. It primarily affects the functioning of the retina, the light-sensitive tissue at the back of the eye, as shown here. Photo credit: National Eye Institute" />
|
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|
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|
||
|
||
</div>
|
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|
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<div class="c-teaser__content">
|
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<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/participants-pioneering-crispr-gene-editing-trial-see-vision-improve">
|
||
Participants of pioneering CRISPR gene editing trial see vision improve
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2024-05-06T11:09:39-04:00">May 6, 2024</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
About 79% of clinical trial participants experienced measurable improvement after receiving experimental, CRISPR-based gene editing that is designed to fix a rare form of blindness.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
||
<div class="field-content"><div class="c-teaser">
|
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<div class="c-teaser__image">
|
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|
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<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2024-03/subretinal-injection_creditOSU_thumb.png?itok=2C6o7P6O" width="200" height="200" alt="" />
|
||
|
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|
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|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/researchers-closing-genetic-treatments-hereditary-lung-disease-vision-loss">
|
||
Researchers closing in on genetic treatments for hereditary lung disease, vision loss
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2024-03-04T12:39:56-05:00">March 4, 2024</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions like inherited vision loss.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
||
<div class="field-content"><div class="c-teaser">
|
||
<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2024-01/canine-blindness_creditTaskinUPenn.jpeg?itok=9AhLpkQw" width="200" height="200" alt="fMRI of dog brain showing bright activation in the visual cortex." />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/using-fmri-new-vision-study-finds-promising-model-restoring-cone-function">
|
||
Using fMRI, new vision study finds promising model for restoring cone function
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2024-01-26T09:50:55-05:00">January 26, 2024</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Researchers have found that in dogs, fMRI can detect brain responses to daylight vision for black and white information as well as color information, and identify the area of the visual cortex that responds to stimulation of a cone-rich retinal region.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
||
<div class="field-content"><div class="c-teaser">
|
||
<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2019-02/normalvspigmentosas.jpg?itok=8Vj-X-GU" width="200" height="200" alt="The image on the left is labeled "Normal retina," and shows green rods and red cones. The image on the right is labeled "Retina affected by retinitis pigmentosa," and shows green rods that have broken down." />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/researchers-engineer-vivo-delivery-system-prime-editing-partially-restoring-vision-mice">
|
||
Researchers engineer in vivo delivery system for prime editing, partially restoring vision in mice
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2024-01-08T11:11:25-05:00">January 8, 2024</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
By adapting virus-like particles to carry the machinery for a type of gene editing called prime editing, scientists have corrected disease-causing mutations in animals and increased editing efficiency.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
||
<div class="field-content"><div class="c-teaser">
|
||
<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2023-10/Nanoparticle.jpg?itok=on1V4UTs" width="200" height="200" alt="" />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/new-gene-editing-technique-holds-potential-treating-childhood-blindness">
|
||
New gene-editing technique holds potential for treating childhood blindness
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2023-10-05T09:20:24-04:00">October 5, 2023</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Using a new experimental technique to fix faulty eye cells, a team led by University of Wisconsin researchers was able to repair a gene mutation that causes one form of childhood blindness.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
||
<div class="field-content"><div class="c-teaser">
|
||
<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2023-04/Dog.jpg?itok=q3QqtyCA" width="200" height="200" alt="" />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/precision-eye-therapy-dogs-ready-human-clinical-development">
|
||
Precision eye therapy for dogs ready for human clinical development
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2023-04-28T09:37:23-04:00">April 28, 2023</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
A successful gene therapy trialed at Michigan State University in dogs with an inherited eye disease is ready to be developed for clinical use in human patients with a rare condition called retinitis pigmentosa.
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Syndrome is a leading cause of combined deafness-blindness
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