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<div> <p>Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.</p>
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163 items
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<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/beltran_still_for_web.jpg?itok=wQHtMpnd" width="200" height="200" alt="Image of gene therapy preserved vision in a study involving dogs." />
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<div class="c-teaser__content">
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<a class="c-teaser__link" href="/about/news-and-events/news/gene-therapy-staves-blindness-retinitis-pigmentosa-canine-model">
|
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Gene Therapy Staves Off Blindness from Retinitis Pigmentosa in Canine Model
|
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</a>
|
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</h2>
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<p class="c-teaser__date">
|
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<time datetime="2015-10-13T13:24:56-04:00">October 13, 2015</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Gene therapy preserved vision in a study involving dogs with naturally occurring, late-stage retinitis pigmentosa, according to research funded by the National Eye Institute (NEI), part of the National Institutes of Health.
|
||
</div>
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</div>
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|
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<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/ND4_gene.jpg?itok=Efdo-2ut" width="200" height="200" alt="Dr. John Guy and colleagues added a homing signal to a virus in order to deliver the ND4 gene into mitochondria. A marker for the gene is shown in red and the ND4 protein is shown in green, inside retinal ganglion cells in the mouse eye. The nuclei of retinal ganglion cells are shown in blue. Credit: Dr. Hong Yu, Bascom Palmer." />
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</div>
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|
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<div class="c-teaser__content">
|
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<h2 class="c-teaser__header">
|
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<a class="c-teaser__link" href="/about/news-and-events/news/scientists-test-new-gene-therapy-vision-loss-mitochondrial-disease">
|
||
Scientists Test New Gene Therapy for Vision Loss From a Mitochondrial Disease
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2015-10-05T09:31:48-04:00">October 5, 2015</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Researchers funded by the National Institutes of Health have developed a novel mouse model for the vision disorder Leber hereditary optic neuropathy (LHON), and found that they can use gene therapy to improve visual function in the mice.
|
||
</div>
|
||
</div>
|
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</div></div></div>
|
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<div class="c-sidebar-widget__list-item views-row">
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<div class="field-content"><div class="c-teaser">
|
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<div class="c-teaser__image">
|
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|
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<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/mice_AQP0_mutations_v2.jpg?itok=xPpOD8P4" width="200" height="200" alt="Mice with AQP0 mutations (top) had disorderly fiber cells compared to mice with healthy AQP0." />
|
||
|
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|
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|
||
</div>
|
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|
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<div class="c-teaser__content">
|
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<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/defective-lens-protein-implicated-cataract-shown-culprit-presbyopia">
|
||
Defective Lens Protein Implicated in Cataract Shown Culprit in Presbyopia
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2015-08-04T00:00:00-04:00">August 4, 2015</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Loss or defects of a protein previously shown to play a key a role in cataract, the clouding of the lens that commonly strikes people in their seventies, has now been shown to contribute to presbyopia.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
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<div class="field-content"><div class="c-teaser">
|
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<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/neural_activity_retina.jpg?itok=381FpiuP" width="200" height="200" alt="Artist's rendering of neural activity in the retina. Light that enters the eye activates rod and cone photoreceptors, which in turn activate retinal ganglion cells. Signals travel to the brain via retinal ganglion cell axons. Photo credit: National Eye Institute." />
|
||
|
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|
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|
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</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/nih-launches-research-gaze-deeply-your-eyes">
|
||
NIH Launches Research to Gaze Deeply Into Your Eyes
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2015-05-01T10:40:09-04:00">May 1, 2015</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Five bold projects will develop new technology to noninvasively image cells of the eye in unprecedented detail.The National Eye Institute (NEI) announced the awards as part of its Audacious Goals Initiative.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
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<div class="field-content"><div class="c-teaser">
|
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<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2019-05/News_Grantee_Placeholder.png?itok=CCnZ6UNM" width="200" height="200" alt="Grantee News" />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/stem-cell-injection-may-soon-reverse-vision-loss-caused-age-related-macular-degeneration">
|
||
Stem Cell Injection May Soon Reverse Vision Loss Caused By Age-Related Macular Degeneration
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2015-04-15T10:30:16-04:00">April 15, 2015</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
||
<div class="field-content"><div class="c-teaser">
|
||
<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/amd-hiv.jpg?itok=bd4IR2lD" width="200" height="200" alt="Degenerated RPE cells from mice with geographic atrophy are shown at left. Treating the mice with NRTIs protected the RPE cells. Photos courtesy of Jayakrishna Ambati, M.D." />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/hiv-drugs-show-promise-dry-amd">
|
||
HIV drugs show promise for “dry” AMD
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2014-12-22T00:00:00-05:00">December 22, 2014</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
A class of medications long used to curb HIV infection shows promise as a therapy for age-related macular degeneration (AMD), suggest findings from an NIH-funded study.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
||
<div class="field-content"><div class="c-teaser">
|
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<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/retinal_pigment_epithelium.jpg?itok=nzRB4oUt" width="200" height="200" alt="Retinal pigment epithelium derived from induced pluripotent stem cells. Photo credit: Dr. Kapil Bharti." />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/gene-profiling-technique-accelerate-stem-cell-therapies-eye-diseases">
|
||
Gene profiling technique to accelerate stem cell therapies for eye diseases
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2014-07-16T00:00:00-04:00">July 16, 2014</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Researchers at the National Institutes of Health have developed a technique that will speed up the production of stem-cell derived tissues.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
||
<div class="field-content"><div class="c-teaser">
|
||
<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2019-05/News_Grantee_Placeholder.png?itok=CCnZ6UNM" width="200" height="200" alt="Grantee News" />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/patient-specific-stem-cells-and-personalized-gene-therapy">
|
||
Patient-Specific Stem Cells and Personalized Gene Therapy
|
||
</a>
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Columbia University Medical Center (CUMC) researchers have created a way to develop personalized gene therapies for patients with retinitis pigmentosa (RP), a leading cause of vision loss.
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Making artificial vision look more natural
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In laboratory tests, researchers have used electrical stimulation of retinal cells to produce the same patterns of activity that occur when the retina sees a moving object.
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Researchers Use Human Stem Cells to Create Light-Sensitive Retina in a Dish
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Using a type of human stem cell, researchers have created a three-dimensional complement of human retinal tissue in the laboratory, which notably includes functioning photoreceptor cells capable of responding to light
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