923 lines
52 KiB
Text
923 lines
52 KiB
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<div> <p>Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.</p>
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<a href="/about/news-and-events/news?initiatives=All&page=1#block-nei-content" class="c-filter__pill">Neurobiology Neurodegeneration and Repair Lab</a><a href="/about/news-and-events/news#block-nei-content" class="c-filter__pill--clear">Clear all filters</a>
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20 items
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<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2020-04/DNA%20methylation%20FINAL.jpg?itok=hj2Q-fg9" width="200" height="200" alt="DNA methylation process" />
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<a class="c-teaser__link" href="/about/news-and-events/news/nei-researchers-link-age-related-dna-modifications-susceptibility-eye-disease">
|
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NEI researchers link age-related DNA modifications to susceptibility to eye disease
|
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</a>
|
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|
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<time datetime="2020-04-21T15:38:10-04:00">April 21, 2020</time>
|
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</p>
|
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<div class="c-teaser__summary">
|
||
National Eye Institute (NEI) researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression.
|
||
</div>
|
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<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2020-04/photoreceptors%20at%203%20mths%20vs2.jpg?itok=HUfS_5UA" width="200" height="200" alt="photoreceptors" />
|
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|
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<a class="c-teaser__link" href="/about/news-and-events/news/researchers-restore-sight-mice-turning-skin-cells-light-sensing-eye-cells">
|
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Researchers restore sight in mice by turning skin cells into light-sensing eye cells
|
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</a>
|
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</h2>
|
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<p class="c-teaser__date">
|
||
<time datetime="2020-04-15T10:12:06-04:00">April 15, 2020</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision. The lab-made rods enabled blind mice to detect light after the cells were transplanted into the animals’ eyes.
|
||
</div>
|
||
</div>
|
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</div></div></div>
|
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<div class="c-sidebar-widget__list-item views-row">
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<div class="field-content"><div class="c-teaser">
|
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<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2019-05/AMD_0.jpg?itok=O2XtvVQj" width="200" height="200" alt="Two boys smile at camera. Dark spot in center of image represents vision loss from AMD." />
|
||
|
||
|
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|
||
</div>
|
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|
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<div class="c-teaser__content">
|
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<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/nih-researchers-home-genes-linked-age-related-macular-degeneration">
|
||
NIH Researchers Home in on Genes Linked to Age-Related Macular Degeneration
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2019-02-11T00:00:00-05:00">February 11, 2019</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration (AMD), a leading cause of vision loss and blindness among people age 65 and older.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
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<div class="field-content"><div class="c-teaser">
|
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<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/CRISPR%20mediated%20NRL%20knockdown_labels%20removed.jpg?itok=mCetOeAU" width="200" height="200" alt="Image of a mouse retina" />
|
||
|
||
|
||
|
||
</div>
|
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|
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<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/nih-scientists-deploy-crispr-preserve-photoreceptors-mice">
|
||
NIH scientists deploy CRISPR to preserve photoreceptors in mice
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2017-03-14T00:00:00-04:00">March 14, 2017</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Silencing a gene called Nrl in mice prevents the loss of cells from degenerative diseases of the retina, according to a new study. The findings could lead to novel therapies for preventing vision loss from human diseases such as retinitis pigmentosa.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
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<div class="field-content"><div class="c-teaser">
|
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<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/Palczewski%20Photo.jpg?itok=5fSrtlNo" width="200" height="200" alt="Retinal degeneration in mice" />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/drugs-already-market-prevent-light-induced-retinal-degeneration-mice">
|
||
Drugs already on market prevent light-induced retinal degeneration in mice
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2016-08-04T00:00:00-04:00">August 4, 2016</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
||
<div class="field-content"><div class="c-teaser">
|
||
<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/rods-and-cones_news_1.jpg?itok=1gi74aLG" width="200" height="200" alt="Rods and Cones image" />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/nih-vision-scientists-test-theory-how-rods-our-retina-originated">
|
||
NIH Vision Scientists Test Theory of How Rods in our Retina Originated
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2016-06-20T00:00:00-04:00">June 20, 2016</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Retinas from our earliest vertebrate ancestors had cone-like photoreceptors, presumably allowing them to see in daylight, but little ability to see at night.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
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<div class="field-content"><div class="c-teaser">
|
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<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/swaroop_photos_1.jpg?itok=GxJmTSxq" width="200" height="200" alt="The researchers developed a technique to study live cells in patches of retina, shown here by confocal microscopy. After 2 hours, the vast majority of the cells are alive (green); only a few cells at the perimeter have died (stained red with a dye)." />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/retinal-cells-work-little-reserve-energy-may-explain-vulnerability-eye-diseases">
|
||
Retinal Cells Work with Little Reserve Energy; May Explain Vulnerability to Eye Diseases
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2016-01-08T00:00:00-05:00">January 8, 2016</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Our eyes are especially demanding when it comes to energy: Along with our brain, they require a substantial amount of power to keep them functioning and healthy.
|
||
</div>
|
||
</div>
|
||
</div></div></div>
|
||
<div class="c-sidebar-widget__list-item views-row">
|
||
<div class="field-content"><div class="c-teaser">
|
||
<div class="c-teaser__image">
|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/news/cilia_grow.jpg?itok=eIbtywen" width="200" height="200" alt="Individual cilia grow from the basal body of a cell with assistance from distal and subdistal appendages (Credit: Shobi Veleri, Ph.D., National Eye Institute)" />
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<div class="c-teaser__content">
|
||
<h2 class="c-teaser__header">
|
||
<a class="c-teaser__link" href="/about/news-and-events/news/nih-study-reveals-gene-critical-early-development-cilia">
|
||
NIH study reveals gene critical to the early development of cilia
|
||
</a>
|
||
</h2>
|
||
<p class="c-teaser__date">
|
||
<time datetime="2014-07-03T13:59:00-04:00">July 3, 2014</time>
|
||
</p>
|
||
<div class="c-teaser__summary">
|
||
Researchers at the National Eye Institute (NEI) have described the functions of a gene responsible for anchoring cilia — sensory hair-like extensions present on almost every cell of the body.
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<img loading="lazy" src="/sites/default/files/styles/thumbnail/public/2019-05/AMD_0.jpg?itok=O2XtvVQj" width="200" height="200" alt="Two boys smile at camera. Dark spot in center of image represents vision loss from AMD." />
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<a class="c-teaser__link" href="/about/news-and-events/news/three-studies-point-same-risk-gene-age-related-macular-degeneration">
|
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Three studies point to same risk gene for age-related macular degeneration
|
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|
||
</h2>
|
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<p class="c-teaser__date">
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<time datetime="2013-09-23T15:35:39-04:00">September 23, 2013</time>
|
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|
||
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|
||
Three studies reported in Nature Genetics have converged on the same gene as a rare, but powerful risk factor for age-related macular degeneration (AMD), a common cause of vision loss in older people.
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<a class="c-teaser__link" href="/about/news-and-events/news/additional-genes-associated-age-related-macular-degeneration-identified">
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Additional Genes Associated with Age-Related Macular Degeneration Identified
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<time datetime="2010-04-12T17:48:34-04:00">April 12, 2010</time>
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<div class="c-teaser__summary">
|
||
A large genetic study of age-related macular degeneration (AMD) has identified three new genes associated with this blinding eye disease-two involved in the cholesterol pathway.
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