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3429 lines
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259 KiB
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<h1 class="res_name"><a href="/gene/">Gene</a></h1>
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<h2 class="res_tagline">Genes and mapped phenotypes</h2>
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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="books">Books</option><option value="structure">Structure</option><option value="omim">OMIM</option><option value="medgen" class="last">MedGen</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<h2 class="offscreen_noflow">Result Filters</h2>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'9315',linkname:'',idsfromresult:'7173',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li><li class="fil_val"><a href="#" data-value_id="seq-refseqgene">RefSeqGene</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67ca1a1969195c35ad7bddb8" data-hid="MCID_67c90f2d64f30b25346ccae2" data-qky="9315" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
|
||
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<span style="display: block; text-align: center;">S</span>
|
||
<span style="display: block; text-align: center;">I</span>
|
||
<span style="display: block; text-align: center;">D</span>
|
||
<span style="display: block; text-align: center;">E</span>
|
||
<span style="display: block; text-align: center;">B</span>
|
||
<span style="display: block; text-align: center;">A</span>
|
||
<span style="display: block; text-align: center;">R</span>
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|
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<div>
|
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|
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|
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</div>
|
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<div class="">
|
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<div><span id="result_sel" class="nowrap"></span><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.ResultCount" sid="1" type="hidden" id="resultcount" value="1" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.RunLastQuery" sid="1" type="hidden" /></div>
|
||
|
||
</div>
|
||
<div id="messagearea" class="empty">
|
||
|
||
<div><ul class="messages" id="FacetsMsg"></ul><div><ul class="messages gene-fc-message"><li class="info icon"><span class="icon">Showing Current items.</span></li></ul></div></div>
|
||
|
||
|
||
</div>
|
||
<div class="rprt full-rprt">
|
||
<div>
|
||
<div class="rprt-header">
|
||
<input type="hidden" id="gene-tax-id" value="9606" />
|
||
<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">TPO</span> thyroid peroxidase [ <em class="tax">Homo sapiens</em> (human)
|
||
]
|
||
</h1>
|
||
<span class="geneid">Gene ID: 7173, updated on
|
||
4-Mar-2025</span>
|
||
</div>
|
||
<div class="download-datasets">
|
||
<script type="text/javascript" src="https://cdnjs.cloudflare.com/ajax/libs/axios/0.23.0/axios.min.js"></script>
|
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<h4 class="download-datasets-popper jig-ncbipopper" id="download-asm" style="align-self:start" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#download-datasets-popper-menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, groupName: 'entrez_pg', adjustFit:'none'" role="button" aria-expanded="false" aria-haspopup="true">
|
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<svg alt="download" class="dlbtn-icon" x="0px" y="0px" width="15px" height="15px" viewBox="0 0 60 60" enable-background="new 0 0 60 60" xml:space="preserve">
|
||
<g>
|
||
<polygon points="48.75,36.25 48.75,48.75 11.25,48.75 11.25,36.25 5,36.25 5,55 55,55 55,36.25 "></polygon>
|
||
<polygon points="42.5,23.75 36.25,23.75 36.25,5 23.75,5 23.75,23.75 17.5,23.75 30,42.5 "></polygon>
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||
</g>
|
||
</svg>
|
||
<a href="#">Download Datasets</a>
|
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</h4>
|
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<div id="download-datasets-popper-menu" style="display:none;">
|
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<div class="input-group">
|
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|
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<label for="datasets-ft-gene-seq-fasta">Gene Sequences (FASTA)</label>
|
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</div>
|
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<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-transcript-seq-fasta" value="FASTA_RNA" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-transcript-seq-fasta">Transcript sequences (FASTA)</label>
|
||
</div>
|
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<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-protein-seq-fasta" value="FASTA_PROTEIN" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-protein-seq-fasta">Protein sequences(FASTA)</label>
|
||
</div>
|
||
<p style="margin-left:5px;">In addition, your package will include a detailed data report in both TSV and JSONL formats.</p>
|
||
<div class="input-group">
|
||
<label for="datasets-download-file-name">File name</label>
|
||
<input type="text" id="datasets-download-file-name" placeholder="Name your file" style="padding:5px;" value="TPO_datasets.zip" />
|
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</div>
|
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<input type="hidden" id="download-datasets-base-url" value="https://api.ncbi.nlm.nih.gov/datasets/v2alpha/gene/download" />
|
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|
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|
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<span class="ui-button-text">Download</span>
|
||
</button>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-body">
|
||
|
||
|
||
<div class="rprt-section gene-summary">
|
||
<section class="rprt-section-header" id="summary">
|
||
<h2 id="header-summary">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-summary .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Summary</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Summary_2" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div id="summaryDiv" class="section">
|
||
<dl id="summaryDl">
|
||
<dt class="noline"> Official
|
||
Symbol</dt>
|
||
<dd class="noline">TPO<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt> Official
|
||
Full Name</dt>
|
||
<dd>thyroid peroxidase<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt>Primary source</dt>
|
||
<dd>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12015" data-gblink-text="Ensembl">HGNC:HGNC:12015</a>
|
||
</dd>
|
||
<dt>See related</dt>
|
||
<dd>
|
||
<a href="http://www.ensembl.org/id/ENSG00000115705" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000115705">Ensembl:ENSG00000115705</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim/606765" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=7173&link_uid=606765">MIM:606765;</a>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:12015" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=7173&link_uid=HGNC:12015">AllianceGenome:HGNC:12015</a>
|
||
</dd>
|
||
<dt>Gene type</dt>
|
||
<dd>protein coding</dd>
|
||
<dt>RefSeq status</dt>
|
||
<dd>REVIEWED</dd>
|
||
<dt>Organism</dt>
|
||
<dd class="tax">
|
||
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&ncbi_uid=7173&link_uid=9606">Homo sapiens</a>
|
||
</dd>
|
||
<dt>Lineage</dt>
|
||
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
|
||
<dt>Also known as</dt>
|
||
<dd>MSA; TPX; TDH2A</dd>
|
||
<dt>Summary</dt>
|
||
<dd>This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]</dd>
|
||
<dt>Annotation information</dt>
|
||
<dd>Note: TPO (Gene ID: 7173) and THPO (Gene ID: 7066) share the TPO symbol/alias in common. TPO is a widely used alternative name for thrombopoietin (THPO), which can be confused with the official symbol for TPO, thyroid peroxidase. [27 Jun 2018]</dd>
|
||
<dt>Expression</dt>
|
||
<dd>Restricted expression toward thyroid (RPKM 463.8) <a href="#gene-expression">See more</a></dd>
|
||
<dt>Orthologs</dt>
|
||
<dd class="ortholog-links">
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene/22018">mouse</a>
|
||
<a href="/gene/7173/ortholog/">all</a>
|
||
</dd>
|
||
<dt style="padding-top:.5em;">
|
||
<span class="new-icon">NEW</span>
|
||
</dt>
|
||
<dd style="padding-top:.5em;">
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/7173/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
|
||
<br />
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/7173/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-genomic-context">
|
||
<section class="rprt-section-header" id="genomic-context">
|
||
<h2 id="header-genomic-context">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-context .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic context</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Context" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="gc_cont">
|
||
<div class="gt_cont_contents">
|
||
<div style="float:right"><span>See TPO in </span><a href="/genome/gdv/?context=gene&acc=7173" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
|
||
<dl class="dl-chr-info" style="float:left;margin-top:0;">
|
||
<dt>Location: </dt>
|
||
<dd>
|
||
<span style="display:inline-block;">2p25.3</span>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
<dl class="dl-chr-info exon-count">
|
||
<dt>Exon count: </dt>
|
||
<dd>22</dd>
|
||
</dl>
|
||
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="">
|
||
<thead>
|
||
<tr>
|
||
<th style="max-width:15%">Annotation release</th>
|
||
<th style="max-width:10%">Status</th>
|
||
<th>Assembly</th>
|
||
<th>
|
||
<span title="Chromosome">Chr</span>
|
||
</th>
|
||
<th>Location</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=7173&link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
|
||
<td>2</td>
|
||
<td>NC_000002.12 (1374047..1543673) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=7173&link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
|
||
<td>2</td>
|
||
<td>NC_060926.1 (1414928..1549090) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_09</td>
|
||
<td>previous assembly</td>
|
||
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=7173&link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
|
||
<td>2</td>
|
||
<td>NC_000002.11 (1417235..1547445) </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<p class="withnote margin_t2em"><strong>Chromosome 2 - NC_000002.12</strong><img usemap="#nbrMap7173_568815596" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=7173&nuc_gi=568815596&n0=SNTG2&n1=LOC124905965&n2=LOC129660567&n3=LOC126806102&n4=LOC122710286&n5=LOC127272277&n6=LOC127272278&n7=LOC127272279&n8=LOC127272280&n9=LOC105373359&n10=LOC127272281&n11=TPO&n12=LOC127272282&n13=LOC127272283&n14=LOC126806103&n15=LOC127272284&n16=LOC124905966&n17=LOC127272285&n18=LOC127272286&n19=LOC127272287&n20=LOC127272288&n21=LOC126806104&n22=LOC129932981&n23=LOC102723730&n24=LOC127272289&n25=LOC127272290&n26=LOC127272291&n27=LOC124907722&n28=LOC127272292&n29=LOC127272293&n30=LOC127272294" /><map name="nbrMap7173_568815596" id="nbrMap7173_568815596">
|
||
<area shape="rect" onMouseOver="showtip(this,event,'syntrophin gamma 2')" onMouseOut="hidetip()" coords="37,23,297,31" alt="Neighboring gene syntrophin gamma 2" href="/gene/54221" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC124905965')" onMouseOut="hidetip()" coords="170,35,240,43" alt="Neighboring gene uncharacterized LOC124905965" href="/gene/124905965" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr2:1260844-1260999')" onMouseOut="hidetip()" coords="173,47,243,55" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr2:1260844-1260999" href="/gene/129660567" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'BRD4-independent group 4 enhancer GRCh37_chr2:1265169-1266368')" onMouseOut="hidetip()" coords="176,59,246,67" alt="Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr2:1265169-1266368" href="/gene/126806102" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 1386')" onMouseOut="hidetip()" coords="188,71,258,79" alt="Neighboring gene Sharpr-MPRA regulatory region 1386" href="/gene/122710286" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1309663-1310386')" onMouseOut="hidetip()" coords="200,83,270,91" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1309663-1310386" href="/gene/127272277" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1310387-1311109')" onMouseOut="hidetip()" coords="201,95,271,103" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1310387-1311109" href="/gene/127272278" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr2:1312058-1312678')" onMouseOut="hidetip()" coords="202,107,272,115" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:1312058-1312678" href="/gene/127272279" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1312679-1313298')" onMouseOut="hidetip()" coords="202,119,272,127" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1312679-1313298" href="/gene/127272280" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105373359')" onMouseOut="hidetip()" coords="203,131,273,139" alt="Neighboring gene uncharacterized LOC105373359" href="/gene/105373359" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:1370519-1371072')" onMouseOut="hidetip()" coords="234,143,304,151" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1370519-1371072" href="/gene/127272281" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:1391744-1392312')" onMouseOut="hidetip()" coords="246,35,316,43" alt="Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:1391744-1392312" href="/gene/127272282" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:1407339-1407839')" onMouseOut="hidetip()" coords="255,47,325,55" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1407339-1407839" href="/gene/127272283" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:1421072-1422271')" onMouseOut="hidetip()" coords="263,59,333,67" alt="Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:1421072-1422271" href="/gene/126806103" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:1451513-1452123')" onMouseOut="hidetip()" coords="280,71,350,79" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1451513-1452123" href="/gene/127272284" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC124905966')" onMouseOut="hidetip()" coords="300,23,394,31" alt="Neighboring gene uncharacterized LOC124905966" href="/gene/124905966" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1492359-1492916')" onMouseOut="hidetip()" coords="302,95,372,103" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1492359-1492916" href="/gene/127272285" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1492917-1493474')" onMouseOut="hidetip()" coords="303,107,373,115" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1492917-1493474" href="/gene/127272286" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:1499759-1500394')" onMouseOut="hidetip()" coords="307,119,377,127" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1499759-1500394" href="/gene/127272287" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:1519727-1520228')" onMouseOut="hidetip()" coords="318,35,388,43" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1519727-1520228" href="/gene/127272288" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:1544276-1545475')" onMouseOut="hidetip()" coords="331,47,401,55" alt="Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:1544276-1545475" href="/gene/126806104" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 11103')" onMouseOut="hidetip()" coords="337,59,407,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11103" href="/gene/129932981" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC102723730')" onMouseOut="hidetip()" coords="338,131,408,139" alt="Neighboring gene uncharacterized LOC102723730" href="/gene/102723730" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'NANOG hESC enhancer GRCh37_chr2:1575946-1576447')" onMouseOut="hidetip()" coords="349,143,419,151" alt="Neighboring gene NANOG hESC enhancer GRCh37_chr2:1575946-1576447" href="/gene/127272289" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:1586454-1586968')" onMouseOut="hidetip()" coords="353,71,423,79" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1586454-1586968" href="/gene/127272290" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:1586969-1587483')" onMouseOut="hidetip()" coords="353,155,423,163" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1586969-1587483" href="/gene/127272291" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC124907722')" onMouseOut="hidetip()" coords="353,167,423,175" alt="Neighboring gene uncharacterized LOC124907722" href="/gene/124907722" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1594967-1595486')" onMouseOut="hidetip()" coords="353,179,423,187" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1594967-1595486" href="/gene/127272292" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1595487-1596006')" onMouseOut="hidetip()" coords="353,191,423,199" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1595487-1596006" href="/gene/127272293" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1596007-1596524')" onMouseOut="hidetip()" coords="353,203,423,211" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1596007-1596524" href="/gene/127272294" />
|
||
</map>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-genomic-regions-transcripts-products">
|
||
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
|
||
<h2 id="header-genomic-regions-transcripts-products">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
|
||
</div>
|
||
<div>
|
||
<p class="choose">
|
||
<label for="accession" class="label">Genomic Sequence: </label>
|
||
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="7173">
|
||
<option value="NC_000002.12_1374046_1543672">NC_000002.12 Chromosome 2 Reference GRCh38.p14 Primary Assembly</option>
|
||
<option value="NT_187529.1_96660_223094">NT_187529.1 Chromosome 2 Reference GRCh38.p14 ALT_REF_LOCI_1</option>
|
||
<option value="NG_011581.2_44417_174627">NG_011581.2 RefSeqGene</option>
|
||
<option value="NC_060926.1_1414927_1549089">NC_060926.1 Chromosome 2 Alternate T2T-CHM13v2.0</option>
|
||
<option value="NC_000002.11_1417234_1547444">NC_000002.11 Chromosome 2 Reference GRCh37.p13 Primary Assembly</option>
|
||
</select>
|
||
</p>
|
||
</div>
|
||
<div id="NC_000002" class="divAccession">
|
||
<div class="seq-viewer">
|
||
<p class="note-link">
|
||
<strong>Go to nucleotide:</strong>
|
||
<a title="Nucleotide Graphic report" href="/nuccore/NC_000002.12?report=graph&from=1348602&to=1569116&app_context=Gene&assm_context=GCF_000001405.40" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NC_000002.12">Graphics</a>
|
||
<a title="Nucleotide FASTA report" href="/nuccore/NC_000002.12?report=fasta&from=1374047&to=1543673" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NC_000002.12">FASTA</a>
|
||
<a title="Nucleotide GenBank report" href="/nuccore/NC_000002.12?report=genbank&from=1374047&to=1543673" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NC_000002.12">GenBank</a>
|
||
</p>
|
||
<div id="divNC_000002" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&embedded=true&noslider=1&id=NC_000002.12&from=1348602&to=1569116&app_context=Gene&assm_context=GCF_000001405.40">
|
||
<a href="?appname=ncbigene&embedded=true&noslider=1&id=NC_000002.12&from=1348602&to=1569116&app_context=Gene&assm_context=GCF_000001405.40"></a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000002.12" sid="1" type="hidden" id="nucleotideLink_NC_000002_12_1374046_1543672" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000002.12?report=graph&amp;from=1348602&amp;to=1569116&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NC_000002.12">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000002.12?report=fasta&amp;from=1374047&amp;to=1543673" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NC_000002.12">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000002.12?report=genbank&amp;from=1374047&amp;to=1543673" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NC_000002.12">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000002.12" sid="1" type="hidden" id="relString_NC_000002_12_1374046_1543672" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000002.12&amp;from=1348602&amp;to=1569116&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NT_187529.1" sid="1" type="hidden" id="nucleotideLink_NT_187529_1_96660_223094" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NT_187529.1?report=graph&amp;from=77695&amp;to=242059&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NT_187529.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NT_187529.1?report=fasta&amp;from=96661&amp;to=223095" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NT_187529.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NT_187529.1?report=genbank&amp;from=96661&amp;to=223095" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NT_187529.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NT_187529.1" sid="1" type="hidden" id="relString_NT_187529_1_96660_223094" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NT_187529.1&amp;from=77695&amp;to=242059&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NG_011581.2" sid="1" type="hidden" id="nucleotideLink_NG_011581_2_44417_174627" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NG_011581.2?report=graph&amp;from=24885&amp;to=194159&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NG_011581.2">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NG_011581.2?report=fasta&amp;from=44418&amp;to=174628" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NG_011581.2">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NG_011581.2?report=genbank&amp;from=44418&amp;to=174628" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NG_011581.2">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NG_011581.2" sid="1" type="hidden" id="relString_NG_011581_2_44417_174627" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NG_011581.2&amp;from=24885&amp;to=194159&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060926.1" sid="1" type="hidden" id="nucleotideLink_NC_060926_1_1414927_1549089" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_060926.1?report=graph&amp;from=1394803&amp;to=1569213&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NC_060926.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_060926.1?report=fasta&amp;from=1414928&amp;to=1549090" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NC_060926.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_060926.1?report=genbank&amp;from=1414928&amp;to=1549090" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NC_060926.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060926.1" sid="1" type="hidden" id="relString_NC_060926_1_1414927_1549089" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_060926.1&amp;from=1394803&amp;to=1569213&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000002.11" sid="1" type="hidden" id="nucleotideLink_NC_000002_11_1417234_1547444" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000002.11?report=graph&amp;from=1397702&amp;to=1566976&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NC_000002.11">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000002.11?report=fasta&amp;from=1417235&amp;to=1547445" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NC_000002.11">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000002.11?report=genbank&amp;from=1417235&amp;to=1547445" ref="ordinalpos=1&amp;ncbi_uid=7173&amp;link_uid=NC_000002.11">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000002.11" sid="1" type="hidden" id="relString_NC_000002_11_1417234_1547444" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000002.11&amp;from=1397702&amp;to=1566976&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" />
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-gene-expression">
|
||
<section class="rprt-section-header" id="gene-expression">
|
||
<h2 id="header-gene-expression">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Expression</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">
|
||
<a href="/gene/7173/?report=expression" data-url="/gene/7173/?report=expression" id="gene-expression-see-details">See details</a>
|
||
</div>
|
||
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/7173" data-report-type="summary">
|
||
<div>
|
||
<script type="text/javascript">
|
||
|
||
window.tissues_data = {'adrenal 10wk': {'id': '7173_Adrenal_10wk_PRJNA270632', 'gene': 7173, 'source_name': 'adrenal 10wk', 'full_rpkm': 0.0214181, 'exp_rpkm': 0.0214, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284754}, 'adrenal 16wk': {'id': '7173_Adrenal_16wk_PRJNA270632', 'gene': 7173, 'source_name': 'adrenal 16wk', 'full_rpkm': 0.0860901, 'exp_rpkm': 0.0861, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284755}, 'adrenal 18wk': {'id': '7173_Adrenal_18wk_PRJNA270632', 'gene': 7173, 'source_name': 'adrenal 18wk', 'full_rpkm': 0.1527, 'exp_rpkm': 0.153, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284756}, 'adrenal 20wk': {'id': '7173_Adrenal_20wk_PRJNA270632', 'gene': 7173, 'source_name': 'adrenal 20wk', 'full_rpkm': 0.0781028, 'exp_rpkm': 0.0781, 'var': 0.00382092, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284757}, 'heart 10wk': {'id': '7173_Heart_10wk;_PRJNA270632', 'gene': 7173, 'source_name': 'heart 10wk', 'full_rpkm': 0.0, 'exp_rpkm': 0.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284758}, 'heart 11wk': {'id': '7173_Heart_11wk;_PRJNA270632', 'gene': 7173, 'source_name': 'heart 11wk', 'full_rpkm': 0.000447851, 'exp_rpkm': 0.000448, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284759}, 'heart 17wk': {'id': '7173_Heart_17wk;_PRJNA270632', 'gene': 7173, 'source_name': 'heart 17wk', 'full_rpkm': 0.00116158, 'exp_rpkm': 0.00116, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284760}, 'heart 18wk': {'id': '7173_Heart_18wk;_PRJNA270632', 'gene': 7173, 'source_name': 'heart 18wk', 'full_rpkm': 0.0, 'exp_rpkm': 0.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284761}, 'heart 20wk': {'id': '7173_Heart_20wk_PRJNA270632', 'gene': 7173, 'source_name': 'heart 20wk', 'full_rpkm': 0.0, 'exp_rpkm': 0.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284762}, 'intestine 10wk': {'id': '7173_Intestine_10wk_PRJNA270632', 'gene': 7173, 'source_name': 'intestine 10wk', 'full_rpkm': 0.00688393, 'exp_rpkm': 0.00688, 'var': 8.44048e-08, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284763}, 'intestine 11wk': {'id': '7173_Intestine_11wk_PRJNA270632', 'gene': 7173, 'source_name': 'intestine 11wk', 'full_rpkm': 0.0, 'exp_rpkm': 0.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284764}, 'intestine 15wk': {'id': '7173_Intestine_15wk_PRJNA270632', 'gene': 7173, 'source_name': 'intestine 15wk', 'full_rpkm': 0.0559903, 'exp_rpkm': 0.056, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284765}, 'intestine 17wk': {'id': '7173_Intestine_17wk_PRJNA270632', 'gene': 7173, 'source_name': 'intestine 17wk', 'full_rpkm': 0.0, 'exp_rpkm': 0.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284766}, 'intestine 20wk': {'id': '7173_Intestine_20wk_PRJNA270632', 'gene': 7173, 'source_name': 'intestine 20wk', 'full_rpkm': 0.00885849, 'exp_rpkm': 0.00886, 'var': 7.84728e-05, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284767}, 'kidney 10wk': {'id': '7173_Kidney_10wk_PRJNA270632', 'gene': 7173, 'source_name': 'kidney 10wk', 'full_rpkm': 0.0379033, 'exp_rpkm': 0.0379, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284768}, 'kidney 16wk': {'id': '7173_Kidney_16wk_PRJNA270632', 'gene': 7173, 'source_name': 'kidney 16wk', 'full_rpkm': 0.0, 'exp_rpkm': 0.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406247284769}, 'kidney 20wk': {'id': '7173_Kidney_20wk_PRJNA270632', 'gene': 7173, 'source_name': 'kidney 20wk', 'full_rpkm': 0.0, 'exp_rpkm': 0.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406248333312}, 'lung 10wk': {'id': '7173_Lung_10wk_PRJNA270632', 'gene': 7173, 'source_name': 'lung 10wk', 'full_rpkm': 0.00678131, 'exp_rpkm': 0.00678, 'var': 4.59862e-05, 'project_desc': 'PRJNA270632', '_version_': 1785734406248333313}, 'lung 17wk': {'id': '7173_Lung_17wk_PRJNA270632', 'gene': 7173, 'source_name': 'lung 17wk', 'full_rpkm': 0.0, 'exp_rpkm': 0.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406248333314}, 'lung 20wk': {'id': '7173_Lung_20wk_PRJNA270632', 'gene': 7173, 'source_name': 'lung 20wk', 'full_rpkm': 0.00130376, 'exp_rpkm': 0.0013, 'var': 1.6998e-06, 'project_desc': 'PRJNA270632', '_version_': 1785734406248333315}, 'stomach 10wk': {'id': '7173_Stomach_10wk_PRJNA270632', 'gene': 7173, 'source_name': 'stomach 10wk', 'full_rpkm': 0.00888952, 'exp_rpkm': 0.00889, 'var': 1.40152e-05, 'project_desc': 'PRJNA270632', '_version_': 1785734406248333316}, 'stomach 16wk': {'id': '7173_Stomach_16wk_PRJNA270632', 'gene': 7173, 'source_name': 'stomach 16wk', 'full_rpkm': 0.0, 'exp_rpkm': 0.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406248333317}, 'stomach 18wk': {'id': '7173_Stomach_18wk_PRJNA270632', 'gene': 7173, 'source_name': 'stomach 18wk', 'full_rpkm': 0.0, 'exp_rpkm': 0.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406248333318}, 'stomach 20wk': {'id': '7173_Stomach_20wk_PRJNA270632', 'gene': 7173, 'source_name': 'stomach 20wk', 'full_rpkm': 0.0034061, 'exp_rpkm': 0.00341, 'var': 2.320308e-05, 'project_desc': 'PRJNA270632', '_version_': 1785734406248333319}};
|
||
|
||
|
||
|
||
|
||
window.details_data = {"adrenal 10wk": [{"id": "metadata_9606_SAMN03267754", "gene": 7173, "sample_id": "SAMN03267754", "full_rpkm": 0.0214181, "exp_rpkm": 0.0214, "exp_total": 430, "project_desc": "PRJNA270632", "_version_": 1785734387345653765, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 10wk", "exp_Mcount": 4852.92}], "adrenal 16wk": [{"id": "metadata_9606_SAMN03267755", "gene": 7173, "sample_id": "SAMN03267755", "full_rpkm": 0.0860901, "exp_rpkm": 0.0861, "exp_total": 2589, "project_desc": "PRJNA270632", "_version_": 1785734387345653764, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 16wk", "exp_Mcount": 7269.31}], "adrenal 18wk": [{"id": "metadata_9606_SAMN03267761", "gene": 7173, "sample_id": "SAMN03267761", "full_rpkm": 0.1527, "exp_rpkm": 0.153, "exp_total": 4217, "project_desc": "PRJNA270632", "_version_": 1785734387345653763, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 18wk", "exp_Mcount": 6675.41}], "adrenal 20wk": [{"id": "metadata_9606_SAMN03267762", "gene": 7173, "sample_id": "SAMN03267762", "full_rpkm": 0.139916, "exp_rpkm": 0.14, "exp_total": 4377, "project_desc": "PRJNA270632", "_version_": 1785734387345653761, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 20wk", "exp_Mcount": 7561.75}, {"id": "metadata_9606_SAMN03267753", "gene": 7173, "sample_id": "SAMN03267753", "full_rpkm": 0.0162893, "exp_rpkm": 0.0163, "exp_total": 448, "project_desc": "PRJNA270632", "_version_": 1785734387345653762, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 20wk", "exp_Mcount": 6647.98}], "heart 10wk": [{"id": "metadata_9606_SAMN03267750", "gene": 7173, "sample_id": "SAMN03267750", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387345653760, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 10wk", "exp_Mcount": 5340.16}], "heart 11wk": [{"id": "metadata_9606_SAMN03267763", "gene": 7173, "sample_id": "SAMN03267763", "full_rpkm": 0.000447851, "exp_rpkm": 0.000448, "exp_total": 11, "project_desc": "PRJNA270632", "_version_": 1785734387344605210, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 11wk", "exp_Mcount": 5937.09}], "heart 17wk": [{"id": "metadata_9606_SAMN03267757", "gene": 7173, "sample_id": "SAMN03267757", "full_rpkm": 0.00116158, "exp_rpkm": 0.00116, "exp_total": 38, "project_desc": "PRJNA270632", "_version_": 1785734387344605209, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 17wk", "exp_Mcount": 7907.66}], "heart 18wk": [{"id": "metadata_9606_SAMN03267751", "gene": 7173, "sample_id": "SAMN03267751", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605208, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 18wk", "exp_Mcount": 6380.91}], "heart 20wk": [{"id": "metadata_9606_SAMN03267756", "gene": 7173, "sample_id": "SAMN03267756", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605205, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 10856.4}, {"id": "metadata_9606_SAMN03267764", "gene": 7173, "sample_id": "SAMN03267764", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605206, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 5097.56}, {"id": "metadata_9606_SAMN03267760", "gene": 7173, "sample_id": "SAMN03267760", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605207, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 5994.06}], "intestine 10wk": [{"id": "metadata_9606_SAMN03267752", "gene": 7173, "sample_id": 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"full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605199, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 20wk", "exp_Mcount": 3894.01}], "kidney 10wk": [{"id": "metadata_9606_SAMN03267784", "gene": 7173, "sample_id": "SAMN03267784", "full_rpkm": 0.0379033, "exp_rpkm": 0.0379, "exp_total": 741, "project_desc": "PRJNA270632", "_version_": 1785734387344605197, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 10wk", "exp_Mcount": 4725.59}], "kidney 16wk": [{"id": "metadata_9606_SAMN03267772", "gene": 7173, "sample_id": "SAMN03267772", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605196, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 16wk", "exp_Mcount": 15288.2}], "kidney 20wk": [{"id": "metadata_9606_SAMN03267777", "gene": 7173, "sample_id": "SAMN03267777", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605195, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 20wk", "exp_Mcount": 10280.0}], "lung 10wk": [{"id": "metadata_9606_SAMN03267770", "gene": 7173, "sample_id": "SAMN03267770", "full_rpkm": 0.0135626, "exp_rpkm": 0.0136, "exp_total": 334, "project_desc": "PRJNA270632", "_version_": 1785734387344605193, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5952.75}, {"id": "metadata_9606_SAMN03267767", "gene": 7173, "sample_id": "SAMN03267767", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605194, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5231.26}], "lung 17wk": [{"id": "metadata_9606_SAMN03267778", "gene": 7173, "sample_id": "SAMN03267778", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605191, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 6254.23}, {"id": "metadata_9606_SAMN03267776", "gene": 7173, "sample_id": "SAMN03267776", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605192, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 3743.33}], "lung 20wk": [{"id": "metadata_9606_SAMN03267780", "gene": 7173, "sample_id": "SAMN03267780", "full_rpkm": 0.00260753, "exp_rpkm": 0.00261, "exp_total": 100, "project_desc": "PRJNA270632", "_version_": 1785734387344605189, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 9270.13}, {"id": "metadata_9606_SAMN03267768", "gene": 7173, "sample_id": "SAMN03267768", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605190, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 6352.54}], "stomach 10wk": [{"id": "metadata_9606_SAMN03267773", "gene": 7173, "sample_id": "SAMN03267773", "full_rpkm": 0.0126332, "exp_rpkm": 0.0126, "exp_total": 344, "project_desc": "PRJNA270632", "_version_": 1785734387344605187, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 6582.02}, {"id": "metadata_9606_SAMN03267779", "gene": 7173, "sample_id": "SAMN03267779", "full_rpkm": 0.00514583, "exp_rpkm": 0.00515, "exp_total": 154, "project_desc": "PRJNA270632", "_version_": 1785734387344605188, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 7234.02}], "stomach 16wk": [{"id": "metadata_9606_SAMN03267774", "gene": 7173, "sample_id": "SAMN03267774", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605186, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 16wk", "exp_Mcount": 6219.43}], "stomach 18wk": [{"id": "metadata_9606_SAMN03267771", "gene": 7173, "sample_id": "SAMN03267771", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605185, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 18wk", "exp_Mcount": 5820.42}], "stomach 20wk": [{"id": "metadata_9606_SAMN03267765", "gene": 7173, "sample_id": "SAMN03267765", "full_rpkm": 0.0102183, "exp_rpkm": 0.0102, "exp_total": 190, "project_desc": "PRJNA270632", "_version_": 1785734387342508032, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4494.58}, {"id": "metadata_9606_SAMN03267781", "gene": 7173, "sample_id": "SAMN03267781", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387343556608, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4566.24}, {"id": "metadata_9606_SAMN03267783", "gene": 7173, "sample_id": "SAMN03267783", "full_rpkm": 0.0, "exp_rpkm": 0.0, "exp_total": 0, "project_desc": "PRJNA270632", "_version_": 1785734387344605184, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4804.58}]}
|
||
window.taxId = 9606
|
||
</script>
|
||
|
||
|
||
<div>
|
||
|
||
|
||
|
||
<select name="p" id="project-selector">
|
||
|
||
|
||
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="SRP056969" data-bioproject="PRJNA280600">
|
||
|
||
RNA sequencing of total RNA from 20 human tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="ERP003613" data-bioproject="PRJEB4337">
|
||
|
||
HPA RNA-seq normal tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
</select>
|
||
|
||
|
||
|
||
<ul id="project-summary">
|
||
<li id="project-summary-title">Project title:
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
|
||
|
||
|
||
|
||
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
|
||
</li>
|
||
|
||
<li id="project-summary-pubs">Publication:
|
||
|
||
|
||
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
<div id="gene-expr-details" class="expression-chart"></div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<script type="text/javascript" src="https://www.gstatic.com/charts/loader.js"></script>
|
||
<script type="text/javascript">
|
||
google.charts.load('current', {
|
||
'packages':[ 'corechart']
|
||
});
|
||
|
||
</script>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-bibliography">
|
||
<section class="rprt-section-header" id="bibliography"><h2 id="header-bibliography"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-bibliography .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Bibliography</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Bibliography" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
<div class="rprt-section-body" style="">
|
||
<div class="generif-pubmed">
|
||
<h3 id="relatedarticlesinpubmed">
|
||
<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
|
||
</h3>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li>
|
||
<a href="/pubmed/16614712/" ref="ordinalpos=1&ncbi_uid=7173&link_uid=16614712">The efficacy of the thyroid peroxidase marker for distinguishing follicular thyroid carcinoma from follicular adenoma.</a>
|
||
<span class="pubmed-auth-date"> Savin S, <em>et al</em>. Exp Oncol, 2006 Mar. PMID 16614712</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/17845204/" ref="ordinalpos=2&ncbi_uid=7173&link_uid=17845204">Value of combined clinical information and thyroid peroxidase antibodies in pregnancy for the prediction of postpartum thyroid dysfunction.</a>
|
||
<span class="pubmed-auth-date"> Mamede da Costa S, <em>et al</em>. Am J Reprod Immunol, 2007 Oct. PMID 17845204</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/17696828/" ref="ordinalpos=3&ncbi_uid=7173&link_uid=17696828">Effects of 12 months treatment with L-selenomethionine on serum anti-TPO Levels in Patients with Hashimoto's thyroiditis.</a>
|
||
<span class="pubmed-auth-date"> Mazokopakis EE, <em>et al</em>. Thyroid, 2007 Jul. PMID 17696828</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/17547680/" ref="ordinalpos=4&ncbi_uid=7173&link_uid=17547680">Two compound heterozygous mutations (c.215delA/c.2422T-->C and c.387delC/c.1159G-->A) in the thyroid peroxidase gene responsible for congenital goitre and iodide organification defect.</a>
|
||
<span class="pubmed-auth-date"> Rivolta CM, <em>et al</em>. Clin Endocrinol (Oxf), 2007 Aug. PMID 17547680</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/17468186/" ref="ordinalpos=5&ncbi_uid=7173&link_uid=17468186">High prevalence of thyroid peroxidase gene mutations in patients with thyroid dyshormonogenesis.</a>
|
||
<span class="pubmed-auth-date"> Avbelj M, <em>et al</em>. Eur J Endocrinol, 2007 May. PMID 17468186</span>
|
||
</li>
|
||
</ol>
|
||
<p class="see-all-pm">
|
||
<a href="/pubmed?LinkName=gene_pubmed&from_uid=7173" title="See all 184 citations in Pubmed">See all (184) citations in PubMed</a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="generif-pubmed generif">
|
||
<h3 id="generifsgenereferencesintofunctions">
|
||
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
|
||
</h3>
|
||
<div>
|
||
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38482822" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=7173&link_uid=38482822">Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity.</a>
|
||
<div id="gene-popper1" class="gene-rif-popper">Title: Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38542286" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=7173&link_uid=38542286">Is There a Link between Thyroid Peroxidase Gene Promoter Polymorphisms and Autoimmune Thyroiditis in the Polish Population?</a>
|
||
<div id="gene-popper2" class="gene-rif-popper">Title: Is There a Link between Thyroid Peroxidase Gene Promoter Polymorphisms and Autoimmune Thyroiditis in the Polish Population?</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/37780999" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=7173&link_uid=37780999">Homozygous Mutations in Thyroid Peroxidase (TPO) in Hypothyroidism with Intellectual Disability, Developmental Delay, and Hearing and Ocular Anomalies in Two Families: Severe Manifestation of Untreated TPO-deficiency Poses a Diagnostic Dilemma.</a>
|
||
<div id="gene-popper3" class="gene-rif-popper">Title: Homozygous Mutations in Thyroid Peroxidase (TPO) in Hypothyroidism with Intellectual Disability, Developmental Delay, and Hearing and Ocular Anomalies in Two Families: Severe Manifestation of Untreated TPO-deficiency Poses a Diagnostic Dilemma.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/37407700" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=7173&link_uid=37407700">TPO as an indicator of lymph node metastasis and recurrence in papillary thyroid carcinoma.</a>
|
||
<div id="gene-popper4" class="gene-rif-popper">Title: TPO as an indicator of lymph node metastasis and recurrence in papillary thyroid carcinoma.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36737753" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=7173&link_uid=36737753">Variants in TPO rs2048722, PTCSC2 rs925489 and SEMA4G rs4919510 affect thyroid carcinoma susceptibility risk.</a>
|
||
<div id="gene-popper5" class="gene-rif-popper">Title: Variants in TPO rs2048722, PTCSC2 rs925489 and SEMA4G rs4919510 affect thyroid carcinoma susceptibility risk.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36989526" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=7173&link_uid=36989526">Longitudinal Associations Between TPO Gene Variants and Thyroid Peroxidase Antibody Seroconversion in a Population-Based Study: Tehran Thyroid Study.</a>
|
||
<div id="gene-popper6" class="gene-rif-popper">Title: Longitudinal Associations Between TPO Gene Variants and Thyroid Peroxidase Antibody Seroconversion in a Population-Based Study: Tehran Thyroid Study.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36537574" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=7173&link_uid=36537574">Cryo-electron microscopy structures of human thyroid peroxidase (TPO) in complex with TPO antibodies.</a>
|
||
<div id="gene-popper7" class="gene-rif-popper">Title: Cryo-electron microscopy structures of human thyroid peroxidase (TPO) in complex with TPO antibodies.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36542322" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=7173&link_uid=36542322">Hypomethylation of Thyroid Peroxidase as a Biomarker for Hepatocellular Carcinoma with Tumor Thrombosis.</a>
|
||
<div id="gene-popper8" class="gene-rif-popper">Title: Hypomethylation of Thyroid Peroxidase as a Biomarker for Hepatocellular Carcinoma with Tumor Thrombosis.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/35507000" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=7173&link_uid=35507000">Mutational screening of the TPO and DUOX2 genes in Argentinian children with congenital hypothyroidism due to thyroid dyshormonogenesis.</a>
|
||
<div id="gene-popper9" class="gene-rif-popper">Title: Mutational screening of the TPO and DUOX2 genes in Argentinian children with congenital hypothyroidism due to thyroid dyshormonogenesis.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/34896620" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=7173&link_uid=34896620">TSH stimulation of human thyroglobulin and thyroid peroxidase gene transcription is partially dependent on internalization.</a>
|
||
<div id="gene-popper10" class="gene-rif-popper">Title: TSH stimulation of human thyroglobulin and thyroid peroxidase gene transcription is partially dependent on internalization.</div>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<div class="submit-genrif">
|
||
<span>Submit:</span>
|
||
<a href="/gene/submit-generif/?geneId=7173&sym=TPO&name=thyroid peroxidase&org=Homo sapiens">New GeneRIF</a>
|
||
<a href="/RefSeq/update.cgi?geneid=7173&symbol=TPO;task=fixpub">Correction</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&report=generif&term=7173" class="seeall-generif">See all GeneRIFs (134)</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-phenotypes">
|
||
<section class="rprt-section-header" id="phenotypes">
|
||
<h2 id="header-phenotypes">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body info-phenotype">
|
||
<p class="nochild-link">
|
||
<a href="/gtr/tests/?term=TPO[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/gap/PheGenI?tab=1&gene=7173">Review eQTL and phenotype association data in this region using PheGenI</a>
|
||
</p>
|
||
<div>
|
||
<h3 id="associatedconditions">Associated conditions</h3>
|
||
<table class="jig-ncbigrid gtr-associated-cond">
|
||
<thead>
|
||
<tr>
|
||
<th class="description">Description</th>
|
||
<th>Tests</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>
|
||
<a href="/gtr/conditions/C1291299" ref="ncbi_uid=7173&link_uid=C1291299">Deficiency of iodide peroxidase</a>
|
||
<div class="gtr-associated-cond-extra">
|
||
<span class="gtr-associated-cond-extra-i">MedGen: <a href="/medgen/C1291299" ref="ncbi_uid=7173&link_uid=C1291299">C1291299</a></span>
|
||
<span class="gtr-associated-cond-extra-i">OMIM: <a href="https://www.ncbi.nlm.nih.gov/omim/274500" ref="ncbi_uid=7173"> 274500</a></span>
|
||
<span class="gtr-associated-cond-extra-i">GeneReviews: <span>Not available</span></span>
|
||
</div>
|
||
</td>
|
||
<td>
|
||
<a href="/gtr/tests/?term=C1291299[DISCUI]&condition=C1291299&compare_labs=1" ref="ncbi_uid=7173">Compare labs</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
<div>
|
||
<h3 id="ebigwascatalog">EBI GWAS Catalog</h3>
|
||
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
|
||
<thead>
|
||
<tr>
|
||
<th class="description">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>A genome-wide association study on thyroid function and anti-thyroid peroxidase antibodies in Koreans.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/24722205">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/24722205">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/24554482">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/24554482">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/24586183">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/24586183">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-variation">
|
||
<section class="rprt-section-header" id="variation">
|
||
<h2 id="header-variation">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Variation</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p class="nochild-link">
|
||
<a href="/clinvar/?term=TPO[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/dbvar?LinkName=gene_dbvar&from_uid=7173" ref="log$=recordlinks">See studies and variants in dbVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=7173[geneid]&assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=7173[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
|
||
</p>
|
||
<set></set>
|
||
<set></set>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-pathways">
|
||
<section class="rprt-section-header" id="pathways">
|
||
<h2 id="header-pathways">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-pathways .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Pathways from PubChem</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<ul class="geneinfo-subsec infopathway">
|
||
<iframe title="Pathways in which the gene target is involved" class="pubchem-widget" scrolling="no" src="https://pubchem.ncbi.nlm.nih.gov/gene/7173#section=Pathways&embed=true&hide_all_headings=true&page_size=25" style="border: 0; width: 100%;"></iframe>
|
||
<script type="text/javascript" src="https://pubchem.ncbi.nlm.nih.gov/pcfe/libs/iframeResizer.min.js"></script>
|
||
<script type="text/javascript">iFrameResize({log: false, checkOrigin: false}, '.pubchem-widget')</script>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-interactions">
|
||
<section class="rprt-section-header" id="interactions">
|
||
<h2 id="header-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/7173/data/interaction/',webserviceParams: 'p$l=Ajax&p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th id="inter-prod">Products</th>
|
||
<th id="inter-interactant">Interactant</th>
|
||
<th id="inter-otherGene">Other Gene</th>
|
||
<th id="inter-compl">Complex</th>
|
||
<th id="inter-source">Source</th>
|
||
<th id="inter-pubs">Pubs</th>
|
||
<th id="inter-desc">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-general-gene-info">
|
||
<section class="rprt-section-header" id="general-gene-info">
|
||
<h2 id="header-general-gene-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General gene information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="gene-markers">
|
||
<h3 id="markers">
|
||
<a class="jig-ncbitoggler">Markers</a>
|
||
</h3>
|
||
<div>
|
||
<ul class="marker odd">
|
||
<li class="marker">GDB:196990 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=155907%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=7173&link_uid=155907">UniSTS:155907</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">D8S2035 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=7452%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=7173&link_uid=7452">UniSTS:7452</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">GDB:197520 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=155936%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=7173&link_uid=155936">UniSTS:155936</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">GDB:196336 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=24890%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=7173&link_uid=24890">UniSTS:24890</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">D2S1515E (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=58695%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=7173&link_uid=58695">UniSTS:58695</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">GDB:181259 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=155227%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=7173&link_uid=155227">UniSTS:155227</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">RH48044 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=61887%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=7173&link_uid=61887">UniSTS:61887</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">GDB:180406 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=155094%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=7173&link_uid=155094">UniSTS:155094</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">TPOX (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=240638%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=7173&link_uid=240638">UniSTS:240638</a></li></ul></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div></div>
|
||
|
||
<div class="infosec">
|
||
<h3 id="homology">
|
||
<a class="jig-ncbitoggler-open">Homology</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>
|
||
<a href="/gene/7173/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
|
||
</li>
|
||
<a href="https://www.orthodb.org/?ncbi=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8178" target="_blank">
|
||
Orthologs from OrthoDB
|
||
</a>
|
||
</ul>
|
||
</div>
|
||
|
||
<!--<component id="Gene_InfoPathway"/>-->
|
||
|
||
|
||
<div class="gene-ontology infosec">
|
||
<h3 id="gene-ontology">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Gene Ontology</span>
|
||
</a>
|
||
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
|
||
</h3>
|
||
<div class="ontology-tables">
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Function</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005509">enables calcium ion binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-1-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0020037">enables heme binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-2-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004447">enables iodide peroxidase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-3-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004601">enables peroxidase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-4-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004601">enables peroxidase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-5-0" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Process</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0098869">involved_in cellular oxidant detoxification</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-1-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0035162">involved_in embryonic hemopoiesis</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-2-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/21149635" target="_blank" title="PubMed ID 21149635" ref="ordinalpos=1&ncbi_uid=7173&link_uid=21149635">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0042446">involved_in hormone biosynthetic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-3-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0042744">involved_in hydrogen peroxide catabolic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-4-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006979">involved_in response to oxidative stress</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-5-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006590">involved_in thyroid hormone generation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-6-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006590">involved_in thyroid hormone generation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-7-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Component</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0009986">located_in cell surface</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-1-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005615">located_in extracellular space</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> HDA</a>
|
||
<div id="evidence-code-2-2" class="ecode">
|
||
<br />
|
||
<a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a>
|
||
</div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/22664934" target="_blank" title="PubMed ID 22664934" ref="ordinalpos=1&ncbi_uid=7173&link_uid=22664934">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005615">is_active_in extracellular space</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-3-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">located_in plasma membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-4-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-general-protein-info">
|
||
<section class="rprt-section-header" id="general-protein-info">
|
||
<h2 id="header-general-protein-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General protein information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<dl>
|
||
<dt>Preferred Names</dt>
|
||
<dd>thyroid peroxidase</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt>Names</dt>
|
||
<dd>thyroid microsomal antigen</dd>
|
||
<dd>thyroperoxidase</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_000538.3</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001193673.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001193674.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_783650.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_783652.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_783653.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_011508682.2</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_024308853.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_024308855.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_024308856.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_024308857.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_024308858.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_024308859.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_024308860.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_024308861.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047301608.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047301609.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047301610.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047301611.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047301612.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047301613.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199614.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199615.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199616.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199617.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199618.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199619.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199620.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199621.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199622.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199623.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199624.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054199625.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/1.11.1.8">1.11.1.8</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-reference-sequences">
|
||
<section class="rprt-section-header" id="reference-sequences">
|
||
<h2 id="header-reference-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p>
|
||
<span class="new-icon">NEW</span>
|
||
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&ids=7173&utm_source=gene&utm_medium=referral&utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
|
||
</p>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
|
||
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
|
||
Genomes</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
|
||
<p id="refseq-expl"> These reference sequences are curated independently of the genome
|
||
annotation cycle, so their versions may not match the RefSeq versions in the current
|
||
genome build. Identify version mismatches by comparing the version of the RefSeq in
|
||
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
|
||
transcripts, and products</a> above. </p>
|
||
<h4 id="genomic-p81959008">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NG_011581.2 RefSeqGene</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>44418..174628</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NG_011581.2?from=44418&to=174628&report=genbank" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NG_011581.2?from=44418&to=174628&report=genbank">GenBank</a>, <a href="/nuccore/NG_011581.2?from=44418&to=174628&report=fasta" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NG_011581.2?from=44418&to=174628&report=fasta">FASTA</a>, <a href="/nuccore/NG_011581.2?from=24885&to=194159&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NG_011581.2?from=24885&to=194159&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p102882256">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/NM_000547.6">NM_000547.6</a> → <a href="/protein/NP_000538.3">NP_000538.3</a> thyroid peroxidase isoform a precursor</p>
|
||
<p>
|
||
<a href="/ipg/NP_000538.3/" ref="ncbi_uid=7173">See identical proteins and their annotated locations for NP_000538.3</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as TPO1).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC141930, AW874082, BC063107, BC095448, J02969">AC141930, AW874082, BC063107, BC095448, J02969</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS1643.1">CCDS1643.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/P07202" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">P07202</a>, <a href="https://www.uniprot.org/uniprot/P09934" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">P09934</a>, <a href="https://www.uniprot.org/uniprot/P09935" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">P09935</a>, <a href="https://www.uniprot.org/uniprot/Q8IUL0" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8IUL0</a>, <a href="https://www.uniprot.org/uniprot/Q8NF94" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8NF94</a>, <a href="https://www.uniprot.org/uniprot/Q8NF95" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8NF95</a>, <a href="https://www.uniprot.org/uniprot/Q8NF96" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8NF96</a>, <a href="https://www.uniprot.org/uniprot/Q8NF97" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8NF97</a>, <a href="https://www.uniprot.org/uniprot/Q8TCI9" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8TCI9</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q502Y3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q502Y3</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000318820.7" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENSP00000318820.7</a>, <a href="http://www.ensembl.org/id/ENST00000345913.8" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENST00000345913.8</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_000538.3">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">742</span> → <span class="cddto">795</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">167</span> → <span class="cddto">734</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=311536">pfam07645</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">796</span> → <span class="cddto">838</span></dt>
|
||
<dd class="clearfix"> EGF_CA; Calcium-binding EGF domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001206744.2">NM_001206744.2</a> → <a href="/protein/NP_001193673.1">NP_001193673.1</a> thyroid peroxidase isoform a precursor</p>
|
||
<p>
|
||
<a href="/ipg/NP_001193673.1/" ref="ncbi_uid=7173">See identical proteins and their annotated locations for NP_001193673.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (6) lacks a segment in the 5' UTR and encodes the same isoform (a, also known as TPO1), compared to variant 1.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC141930, BC095448, Y00406">AC141930, BC095448, Y00406</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS1643.1">CCDS1643.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/P07202" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">P07202</a>, <a href="https://www.uniprot.org/uniprot/P09934" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">P09934</a>, <a href="https://www.uniprot.org/uniprot/P09935" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">P09935</a>, <a href="https://www.uniprot.org/uniprot/Q8IUL0" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8IUL0</a>, <a href="https://www.uniprot.org/uniprot/Q8NF94" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8NF94</a>, <a href="https://www.uniprot.org/uniprot/Q8NF95" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8NF95</a>, <a href="https://www.uniprot.org/uniprot/Q8NF96" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8NF96</a>, <a href="https://www.uniprot.org/uniprot/Q8NF97" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8NF97</a>, <a href="https://www.uniprot.org/uniprot/Q8TCI9" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q8TCI9</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q502Y3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q502Y3</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000329869.4" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENSP00000329869.4</a>, <a href="http://www.ensembl.org/id/ENST00000329066.9" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENST00000329066.9</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001193673.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">742</span> → <span class="cddto">795</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">167</span> → <span class="cddto">734</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=311536">pfam07645</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">796</span> → <span class="cddto">838</span></dt>
|
||
<dd class="clearfix"> EGF_CA; Calcium-binding EGF domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001206745.2">NM_001206745.2</a> → <a href="/protein/NP_001193674.1">NP_001193674.1</a> thyroid peroxidase isoform b precursor</p>
|
||
<p>
|
||
<a href="/ipg/NP_001193674.1/" ref="ncbi_uid=7173">See identical proteins and their annotated locations for NP_001193674.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (7) lacks a segment in the 5' UTR and an in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (b, also known as TPO2) that is shorter than isoform a.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC141930, BC063107, BE046044, J02969, X17358">AC141930, BC063107, BE046044, J02969, X17358</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS1644.1">CCDS1644.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q502Y3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q502Y3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001193674.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">685</span> → <span class="cddto">738</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">167</span> → <span class="cddto">677</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281139">pfam03098</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">151</span> → <span class="cddto">642</span></dt>
|
||
<dd class="clearfix"> An_peroxidase; Animal haem peroxidase</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=284955">pfam07645</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">739</span> → <span class="cddto">781</span></dt>
|
||
<dd class="clearfix"> EGF_CA; Calcium-binding EGF domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_175719.4">NM_175719.4</a> → <a href="/protein/NP_783650.1">NP_783650.1</a> thyroid peroxidase isoform b precursor</p>
|
||
<p>
|
||
<a href="/ipg/NP_783650.1/" ref="ncbi_uid=7173">See identical proteins and their annotated locations for NP_783650.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (2) lacks an an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (b, also known as TPO2) that is shorter than isoform a.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC141930, AW874082, BC063107, BC095448, J02970">AC141930, AW874082, BC063107, BC095448, J02970</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS1644.1">CCDS1644.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q502Y3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q502Y3</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000371636.3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENSP00000371636.3</a>, <a href="http://www.ensembl.org/id/ENST00000382201.7" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENST00000382201.7</a></dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_783650.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">685</span> → <span class="cddto">738</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">167</span> → <span class="cddto">677</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281139">pfam03098</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">151</span> → <span class="cddto">642</span></dt>
|
||
<dd class="clearfix"> An_peroxidase; Animal haem peroxidase</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=284955">pfam07645</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">739</span> → <span class="cddto">781</span></dt>
|
||
<dd class="clearfix"> EGF_CA; Calcium-binding EGF domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_175721.3">NM_175721.3</a> → <a href="/protein/NP_783652.1">NP_783652.1</a> thyroid peroxidase isoform d precursor</p>
|
||
<p>
|
||
<a href="/ipg/NP_783652.1/" ref="ncbi_uid=7173">See identical proteins and their annotated locations for NP_783652.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (4) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (d, also known as TPO4) compared to isoform a. This variant lacks the 5'-most non-coding exon because of alternate splicing, the extension at the 5' end is uncertain.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AW874082, AY136822, CB986756, DA958481, M55702, X17358, Y00406">AW874082, AY136822, CB986756, DA958481, M55702, X17358, Y00406</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q502Y3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q502Y3</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000263886.6" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENSP00000263886.6</a>, <a href="http://www.ensembl.org/id/ENST00000346956.7" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENST00000346956.7</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_783652.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">742</span> → <span class="cddto">795</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">167</span> → <span class="cddto">734</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281139">pfam03098</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">151</span> → <span class="cddto">699</span></dt>
|
||
<dd class="clearfix"> An_peroxidase; Animal haem peroxidase</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_175722.3">NM_175722.3</a> → <a href="/protein/NP_783653.1">NP_783653.1</a> thyroid peroxidase isoform e precursor</p>
|
||
<p>
|
||
<a href="/ipg/NP_783653.1/" ref="ncbi_uid=7173">See identical proteins and their annotated locations for NP_783653.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (5) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (e, also known as TPO5) that is shorter than isoform a. This variant lacks the 5'-most non-coding exon because of alternate splicing, the extension at the 5' end is uncertain.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AF439430, AF533528, AW874082, BC095448, CD608890, DA958481">AF439430, AF533528, AW874082, BC095448, CD608890, DA958481</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS1646.1">CCDS1646.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q502Y3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q502Y3</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000371633.1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENSP00000371633.1</a>, <a href="http://www.ensembl.org/id/ENST00000382198.5" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENST00000382198.5</a></dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_783653.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">569</span> → <span class="cddto">622</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=265428">cl14561</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span> → <span class="cddto">561</span></dt>
|
||
<dd class="clearfix"> An_peroxidase_like; Animal heme peroxidases and related proteins</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281139">pfam03098</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">151</span> → <span class="cddto">526</span></dt>
|
||
<dd class="clearfix"> An_peroxidase; Animal haem peroxidase</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=284955">pfam07645</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">623</span> → <span class="cddto">665</span></dt>
|
||
<dd class="clearfix"> EGF_CA; Calcium-binding EGF domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
|
||
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> The following sections contain reference sequences that belong to a
|
||
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
|
||
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
|
||
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
|
||
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
|
||
assemblies. Model RNAs and proteins are also reported here.</p>
|
||
<h3 id="refseq-sequencedescription-p69408816">Reference GRCh38.p14 Primary Assembly</h3>
|
||
<h4 id="genomic-p69408816">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_000002.12 Reference GRCh38.p14 Primary Assembly</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>1374047..1543673</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_000002.12?from=1374047&to=1543673&report=genbank" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NC_000002.12?from=1374047&to=1543673&report=genbank">GenBank</a>, <a href="/nuccore/NC_000002.12?from=1374047&to=1543673&report=fasta" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NC_000002.12?from=1374047&to=1543673&report=fasta">FASTA</a>, <a href="/nuccore/NC_000002.12?from=1348602&to=1569116&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NC_000002.12?from=1348602&to=1569116&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p77302176">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047445652.1">XM_047445652.1</a> → <a href="/protein/XP_047301608.1">XP_047301608.1</a> thyroid peroxidase isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/H0Y6H4" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">H0Y6H4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047445655.1">XM_047445655.1</a> → <a href="/protein/XP_047301611.1">XP_047301611.1</a> thyroid peroxidase isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/H0Y6H4" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">H0Y6H4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047445654.1">XM_047445654.1</a> → <a href="/protein/XP_047301610.1">XP_047301610.1</a> thyroid peroxidase isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/H0Y6H4" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">H0Y6H4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047445656.1">XM_047445656.1</a> → <a href="/protein/XP_047301612.1">XP_047301612.1</a> thyroid peroxidase isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/H0Y6H4" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">H0Y6H4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047445653.1">XM_047445653.1</a> → <a href="/protein/XP_047301609.1">XP_047301609.1</a> thyroid peroxidase isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/H0Y6H4" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">H0Y6H4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_024453089.2">XM_024453089.2</a> → <a href="/protein/XP_024308857.1">XP_024308857.1</a> thyroid peroxidase isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/H0Y6H4" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">H0Y6H4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_024308857.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">742</span> → <span class="cddto">795</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">167</span> → <span class="cddto">734</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011510380.4">XM_011510380.4</a> → <a href="/protein/XP_011508682.2">XP_011508682.2</a> thyroid peroxidase isoform X2</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q53QT2" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q53QT2</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011508682.2">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">754</span> → <span class="cddto">807</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">179</span> → <span class="cddto">746</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=311536">pfam07645</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">808</span> → <span class="cddto">850</span></dt>
|
||
<dd class="clearfix"> EGF_CA; Calcium-binding EGF domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_024453090.2">XM_024453090.2</a> → <a href="/protein/XP_024308858.1">XP_024308858.1</a> thyroid peroxidase isoform X4</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q502Y3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q502Y3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_024308858.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">754</span> → <span class="cddto">807</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">179</span> → <span class="cddto">746</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047445657.1">XM_047445657.1</a> → <a href="/protein/XP_047301613.1">XP_047301613.1</a> thyroid peroxidase isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q53QT2" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q53QT2</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_024453091.2">XM_024453091.2</a> → <a href="/protein/XP_024308859.1">XP_024308859.1</a> thyroid peroxidase isoform X6</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q502Y3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q502Y3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_024308859.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">697</span> → <span class="cddto">750</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">179</span> → <span class="cddto">689</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=311536">pfam07645</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">751</span> → <span class="cddto">793</span></dt>
|
||
<dd class="clearfix"> EGF_CA; Calcium-binding EGF domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_024453092.2">XM_024453092.2</a> → <a href="/protein/XP_024308860.1">XP_024308860.1</a> thyroid peroxidase isoform X7</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q502Y3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q502Y3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_024308860.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">697</span> → <span class="cddto">750</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">179</span> → <span class="cddto">689</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_024453093.2">XM_024453093.2</a> → <a href="/protein/XP_024308861.1">XP_024308861.1</a> thyroid peroxidase isoform X8</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q502Y3" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q502Y3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_024308861.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">581</span> → <span class="cddto">634</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=311536">pfam07645</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">635</span> → <span class="cddto">677</span></dt>
|
||
<dd class="clearfix"> EGF_CA; Calcium-binding EGF domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=326323">cl14561</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">13</span> → <span class="cddto">573</span></dt>
|
||
<dd class="clearfix"> An_peroxidase_like; Animal heme peroxidases and related proteins</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_024453085.2">XM_024453085.2</a> → <a href="/protein/XP_024308853.1">XP_024308853.1</a> thyroid peroxidase isoform X1</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/H0Y6H4" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">H0Y6H4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_024308853.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">754</span> → <span class="cddto">807</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">179</span> → <span class="cddto">746</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_024453088.2">XM_024453088.2</a> → <a href="/protein/XP_024308856.1">XP_024308856.1</a> thyroid peroxidase isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/H0Y6H4" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">H0Y6H4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_024308856.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">742</span> → <span class="cddto">795</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">167</span> → <span class="cddto">734</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_024453087.2">XM_024453087.2</a> → <a href="/protein/XP_024308855.1">XP_024308855.1</a> thyroid peroxidase isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/H0Y6H4" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">H0Y6H4</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000405788.1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENSP00000405788.1</a>, <a href="http://www.ensembl.org/id/ENST00000422464.5" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">ENST00000422464.5</a></dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_024308855.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=153056">cd00033</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">742</span> → <span class="cddto">795</span></dt>
|
||
<dd class="clearfix"> CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=188657">cd09825</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">167</span> → <span class="cddto">734</span></dt>
|
||
<dd class="clearfix"> thyroid_peroxidase; Thyroid peroxidase (TPO)</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h3 id="refseq-sequencedescription-p26302992">Reference GRCh38.p14 ALT_REF_LOCI_1</h3>
|
||
<h4 id="genomic-p26302992">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NT_187529.1 Reference GRCh38.p14 ALT_REF_LOCI_1</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>96661..223095</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NT_187529.1?from=96661&to=223095&report=genbank" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NT_187529.1?from=96661&to=223095&report=genbank">GenBank</a>, <a href="/nuccore/NT_187529.1?from=96661&to=223095&report=fasta" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NT_187529.1?from=96661&to=223095&report=fasta">FASTA</a>, <a href="/nuccore/NT_187529.1?from=77695&to=242059&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NT_187529.1?from=77695&to=242059&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h3 id="refseq-sequencedescription-p96351232">Alternate T2T-CHM13v2.0</h3>
|
||
<h4 id="genomic-p96351232">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_060926.1 Alternate T2T-CHM13v2.0</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>1414928..1549090</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_060926.1?from=1414928&to=1549090&report=genbank" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NC_060926.1?from=1414928&to=1549090&report=genbank">GenBank</a>, <a href="/nuccore/NC_060926.1?from=1414928&to=1549090&report=fasta" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NC_060926.1?from=1414928&to=1549090&report=fasta">FASTA</a>, <a href="/nuccore/NC_060926.1?from=1394803&to=1569213&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=7173&link_uid=NC_060926.1?from=1394803&to=1569213&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p102858320">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343642.1">XM_054343642.1</a> → <a href="/protein/XP_054199617.1">XP_054199617.1</a> thyroid peroxidase isoform X10</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0M8X1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">A0M8X1</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343640.1">XM_054343640.1</a> → <a href="/protein/XP_054199615.1">XP_054199615.1</a> thyroid peroxidase isoform X10</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0M8X1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">A0M8X1</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343641.1">XM_054343641.1</a> → <a href="/protein/XP_054199616.1">XP_054199616.1</a> thyroid peroxidase isoform X10</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0M8X1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">A0M8X1</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343646.1">XM_054343646.1</a> → <a href="/protein/XP_054199621.1">XP_054199621.1</a> thyroid peroxidase isoform X13</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q53QT2" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q53QT2</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343645.1">XM_054343645.1</a> → <a href="/protein/XP_054199620.1">XP_054199620.1</a> thyroid peroxidase isoform X12</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0M8X1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">A0M8X1</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343650.1">XM_054343650.1</a> → <a href="/protein/XP_054199625.1">XP_054199625.1</a> thyroid peroxidase isoform X15</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0M8X1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">A0M8X1</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343643.1">XM_054343643.1</a> → <a href="/protein/XP_054199618.1">XP_054199618.1</a> thyroid peroxidase isoform X1</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q59GZ9" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q59GZ9</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343639.1">XM_054343639.1</a> → <a href="/protein/XP_054199614.1">XP_054199614.1</a> thyroid peroxidase isoform X9</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q53QT2" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">Q53QT2</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343647.1">XM_054343647.1</a> → <a href="/protein/XP_054199622.1">XP_054199622.1</a> thyroid peroxidase isoform X14</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0M8X1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">A0M8X1</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343648.1">XM_054343648.1</a> → <a href="/protein/XP_054199623.1">XP_054199623.1</a> thyroid peroxidase isoform X4</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0M8X1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">A0M8X1</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343644.1">XM_054343644.1</a> → <a href="/protein/XP_054199619.1">XP_054199619.1</a> thyroid peroxidase isoform X11</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0M8X1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">A0M8X1</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054343649.1">XM_054343649.1</a> → <a href="/protein/XP_054199624.1">XP_054199624.1</a> thyroid peroxidase isoform X6</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0M8X1" ref="itool=Gene_FullReport&PrId=5380&uid=7173&nlmid=&db=gene">A0M8X1</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<h3 class="genomerefseqs gene_std_toggler">
|
||
<a class="jig-ncbitoggler">Suppressed Reference Sequence(s)</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> The following Reference Sequences have been suppressed. <a href="#expl-suppressed-desc" id="expl-suppressed">Explain</a></p>
|
||
<p id="expl-suppressed-desc" style="display:none">These RefSeqs were suppressed for the
|
||
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
|
||
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
|
||
their accession.version below.</p>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/28558985">NM_175720.1</a>: Suppressed sequence</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>NM_175720.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-related-sequences">
|
||
<section class="rprt-section-header" id="related-sequences">
|
||
<h2 id="header-related-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Related sequences</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/7173/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th colspan="2" id="rs-nucleo">Nucleotide</th>
|
||
<th rowspan="2" id="rs-protein">Protein</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-heading">Heading</th>
|
||
<th id="rs-heading-acc">Accession and Version</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
|
||
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-genepept">GenPept Link</th>
|
||
<th id="rs-uniprot">UniProtKB Link</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="rs-prot-acc">P07202.4</td>
|
||
<td headers="rs-link rs-genepept">
|
||
<a href="/protein/160281455" ref="ordinalpos=1&ncbi_uid=7173&link_uid=160281455">GenPept</a>
|
||
</td>
|
||
<td>
|
||
<a href="https://www.uniprot.org/uniprot/P07202">UniProtKB/Swiss-Prot:P07202</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-additional-links">
|
||
|
||
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="lsdb"><h3 class="withnote" id="locusspecificdatabases"><a class="jig-ncbitoggler-open">Locus-specific Databases</a></h3><div><ul class="locusdb"><li><a href="http://databases.lovd.nl/shared/genes/TPO" ref="from_uid=7173" class="lsdblink">TPO database</a></li></ul></div></div>
|
||
|
||
<h3 class="withnote" id="genelinkout">
|
||
<a class="jig-ncbitoggler">Gene LinkOut</a>
|
||
</h3><div>
|
||
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
|
||
<div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Other Literature Sources</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Dryad Digital Repository</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://datadryad.org/stash/dataset/doi:10.5061/dryad.5230v" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=7893">
|
||
<span>Dryad Digital Repository</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Chemical Information</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=7911">
|
||
<span>Interologous Interaction Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>MilliporeSigma</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/TPO?lang=en&region=US" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=9978">
|
||
<span>Tpo products</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Medical</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>MedlinePlus Health Information</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://medlineplus.gov/genetics/gene/tpo" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=3162">
|
||
<span>TPO gene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Molecular Biology Databases</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Bgee database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000115705" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=10418">
|
||
<span>TPO gene expression</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGPS</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://biogps.org/gene/7173/" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=5059">
|
||
<span>BioGPS</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=10164">
|
||
<span>BioGRID CRISPR Screen Phenotypes (14 hits/1360 screens)</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&format=genome&entry=TPO_1" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=9624">
|
||
<span>TPO_1</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://glygen.org/protein/P07202" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=10227">
|
||
<span>GlyGen glycoinformatics resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Guide to Pharmacology</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2526" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8191">
|
||
<span>thyroid peroxidase gene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span><span class="regis-rsc"></span>Human Gene Mutation Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.hgmd.cf.ac.uk/ac/gene.php?gene=TPO" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=3100">
|
||
<span>Human Gene Mutation Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Human eFP Browser</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&modeInput=Absolute&primaryGene=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&modeInput=Absolute&primaryGene=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Nervous&modeInput=Absolute&primaryGene=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>Ingenuity Pathways Analysis</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&p1=Entrez&p2=GV&s=&ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D7173%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=5628">
|
||
<span>Ingenuity Pathways Analysis</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InnateDB</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=25524" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=7894">
|
||
<span>InnateDB</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InterMine</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000115705" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=9169">
|
||
<span>InterMine</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=5174">
|
||
<span>Kyoto Encyclopedia of Genes and Genomes</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN61326/" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN61328/" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN61329/" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.orthodb.org/?ncbi=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8178">
|
||
<span>Orthologs</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=7987">
|
||
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=TPO" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8598">
|
||
<span>GeneCard for TPO</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Research Materials</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://addgene.org//browse/gene/7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=5304">
|
||
<span>Get Plasmids - Addgene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Bio-Techne</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/thyroid-peroxidase/antibodies?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=antibodies" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>Thyroid Peroxidase Antibodies</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/thyroid-peroxidase/proteins-enzymes?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=proteins" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>Thyroid Peroxidase Proteins</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/thyroid-peroxidase/elisa-kits?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=elisakits" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>Thyroid Peroxidase ELISA Kits</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Creative Biogene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.creative-biogene.com/genesearch/TPO.html" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=10094">
|
||
<span>thyroid peroxidase</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>ExactAntigen/Labome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/review/gene/human/thyroid-peroxidase-antibody.html" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagent review</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/gene/human/thyroid-peroxidase-antibody.html" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagents</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genscript.com/gene/7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8012">
|
||
<span>GenScript latest version of gene cDNA ORF Clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=26&field=5&key=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order TALEN/CRISPR clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?tax_id=9606&field=5&prt=16&key=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order miRNA target clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&field=5&key=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order full-length ORF clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneTex Inc</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=7173&type=03&page=1" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8117">
|
||
<span>Find Recombinant Proteins and Peptides</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=7173&type=01&page=1" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=8117">
|
||
<span>Find Quality Antibodies</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>OriGene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.origene.com/search?q=Tpo" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=7994">
|
||
<span>Order Tpo cDNA clone/Protein/Antibody/RNAi</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Tools</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>GeneMANIA</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://genemania.org/link?o=9606&g=7173" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=7529">
|
||
<span>GeneMANIA</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Miscellaneous</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Reactome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://reactome.org/content/query?q=UniProt:P07202" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=4914">
|
||
<span>Reactome Entity:P07202</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-1430728" ref="itool=Gene_FullReport&uid=7173&nlmid=&db=gene&log$=linkoutlink&PrId=4914">
|
||
<span>Reactome Event:Metabolism</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="urls-in-genombrowser" style="display:none">
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div><input type="hidden" class="section_status_input" name="status_checked" id="status_checked" value="" /><input type="hidden" class="section_status_input" name="status_open" id="status_open" value="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_exist" id="status_exist" value="summary,context,region,expression,bibliography,phenotypes,variation,,interactions,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_closed" id="status_closed" value="" /><meta name="status_checked" content="" class="meta_section_status" /><meta name="status_open" content="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_exist" content="summary,context,region,expression,bibliography,phenotypes,variation,,interactions,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_closed" content="" class="meta_section_status" /><script type="text/javascript">
|
||
|
||
var section_status_meta = {
|
||
'status_checked': '',
|
||
'status_open': 'summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_exist': 'summary,context,region,expression,bibliography,phenotypes,variation,,interactions,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_closed': ''
|
||
};
|
||
|
||
|
||
/*
|
||
for (var o in section_status_meta) {
|
||
var meta=document.createElement('meta');
|
||
meta.name = o;
|
||
meta.content = section_status_meta[o];
|
||
var attr = document.createAttribute('data-ignore-limit');
|
||
attr.value = 'true';
|
||
meta.setAttributeNode(attr);
|
||
document.getElementsByTagName('head')[0].appendChild(meta);
|
||
}
|
||
*/
|
||
|
||
|
||
var __ncbi_sg_pingCallbacks_render_gene = function (data, evtObj, type) {
|
||
// data looks like {jsevent: "click", "link_id": "foo", ...}
|
||
// evtObj is the JS event object
|
||
// type is either "stat" (for applog) or "ga"
|
||
var extraData = {};
|
||
if (type == "stat") {
|
||
for (var o in section_status_meta) {
|
||
extraData[o] = section_status_meta[o];
|
||
}
|
||
|
||
return extraData;
|
||
|
||
}
|
||
}
|
||
|
||
|
||
</script></div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last" id="sidebar_tabular">
|
||
<!-- sidebar close/hide button-->
|
||
<div class="ui-helper-clearfix">
|
||
<a href="#" id="sidecontent_2_pullout" style="float:right;" class="sidecontentpullout_local collapse_button"><span>Hide sidebar >></span></a>
|
||
</div>
|
||
<!-- end sidebar close/hide button-->
|
||
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div id="gene-sidebar">
|
||
<div>
|
||
<div class="portlet brieflink dis-table-of-contents">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Table of contents</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li class="">
|
||
<a href="#summary">Summary</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-context">Genomic context</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#gene-expression">Expression</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#bibliography">Bibliography</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#phenotypes">Phenotypes</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#variation">Variation</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#pathways">Pathways from PubChem</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#interactions">Interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-gene-info">General gene information</a>
|
||
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-protein-info">General protein information</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#related-sequences">Related sequences</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#additional-links">Additional links</a>
|
||
<div class="subsection-links">
|
||
<a href="#lsdb">Locus-specific Databases</a>
|
||
</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Genome Browsers</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GenomeBrowsers" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="#">Loading...</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-related-info brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clone/order/gene/7173" ref="log$=recordlinks">Order cDNA clone</a>
|
||
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&from_uid=7173" ref="log$=recordlinks">BioAssay by Target (List)</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="//pubchem.ncbi.nlm.nih.gov/assay/bioactivity.html?geneid=7173" ref="log$=recordlinks">BioAssay by Target (Summary)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Summarized PubChem Data on the gene, showing the active data by default</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&from_uid=7173" ref="log$=recordlinks">BioAssay, by Gene target</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai_active&from_uid=7173" ref="log$=recordlinks">BioAssays, RNAi Target, Active</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent, which is identified as a hit in a RNAi screening and flagged as "active" in the corresponding BioAssay record</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&from_uid=7173" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&from_uid=7173" ref="log$=recordlinks">BioProjects</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&from_uid=7173" ref="log$=recordlinks">BioSystems</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&DATA=7173" ref="log$=recordlinks">CCDS</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&from_uid=7173" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&from_uid=7173" ref="log$=recordlinks">Conserved Domains</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&from_uid=7173" ref="log$=recordlinks">dbVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&from_uid=7173" ref="log$=recordlinks">Full text in PMC</a>
|
||
<div class="brieflinkpop offscreen_noflow">PMC links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&from_uid=7173" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&from_uid=7173" ref="log$=recordlinks">Functional Class</a>
|
||
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&from_uid=7173" ref="log$=recordlinks">Gene neighbors</a>
|
||
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&from_uid=7173" ref="log$=recordlinks">Genome</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&from_uid=7173" ref="log$=recordlinks">GEO Profiles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=7173[geneid]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&from_uid=7173" ref="log$=recordlinks">HomoloGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/medgen?LinkName=gene_medgen_diseases&from_uid=7173" ref="log$=recordlinks">MedGen</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in MedGen</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&from_uid=7173" ref="log$=recordlinks">Nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&from_uid=7173" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&from_uid=7173" ref="log$=recordlinks">Probe</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&from_uid=7173" ref="log$=recordlinks">Protein</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&from_uid=7173" ref="log$=recordlinks">PubChem Compound</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&from_uid=7173" ref="log$=recordlinks">PubChem Substance</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&from_uid=7173" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&from_uid=7173" ref="log$=recordlinks">PubMed (GeneRIF)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&from_uid=7173" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&from_uid=7173" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&from_uid=7173" ref="log$=recordlinks">RefSeq Proteins</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&from_uid=7173" ref="log$=recordlinks">RefSeq RNAs</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore/2310187194?report=graph" ref="log$=recordlinks">RefSeqGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeqGenes</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar_specific&from_uid=7173" ref="log$=recordlinks">Related gene-specific medical variations</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&from_uid=7173" ref="log$=recordlinks">SNP</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&from_uid=7173" ref="log$=recordlinks">Taxonomy</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/variation/view/?q=7173[geneid]" ref="log$=recordlinks">Variation Viewer</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-links-to-other-res brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Links to other resources</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12015">HGNC</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.ensembl.org/id/ENSG00000115705">Ensembl</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:12015">AllianceGenome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&org=9606&l=7173">AceView</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://databases.lovd.nl/shared/genes/TPO">TPO database</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=NM_000547">UCSC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&LIST=BC095448">MGC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=TPO&geneID=7173&typeOption=gene&which=2&pubOrderType=pubD&typeSubmit=GO&check=y">HuGE Navigator</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:7173">KEGG</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://reactome.org/content/query?q=UniProt:P07202">Reactome</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-general-info">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>General information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3840">FAQ</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3841/">Help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3842/">My NCBI help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK21085/">NCBI Handbook</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/statistics/">Statistics</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-related-sites">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related sites</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_RelatedSites" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-feedback">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Feedback</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Feedback" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&deptID=28049">Contact Help Desk</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=7173&symbol=TPO">Submit Correction</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/submit-generif?geneId=7173&sym=TPO&name=thyroid peroxidase&org=Homo sapiens">Submit GeneRIF</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-subscription">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Subscription</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Subscription" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<!-- <component id="Gene_RVFullReport.Gene_RightColMenuLinks"/>-->
|
||
<div class="portlet">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Recent activity</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<div id="HTDisplay" class="">
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Cmd" sid="1" type="hidden" />
|
||
<div class="action">
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory">
|
||
Clear
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn Off
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="2" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOff" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn On
|
||
</a>
|
||
</div>
|
||
<ul id="activity">
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67ca1a19b15b832ebc483c2d">TPO thyroid peroxidase [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">TPO thyroid peroxidase [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:7173</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67ca1a17a68b6b5afcaa1c8d">thyroid peroxidase isoform a precursor [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">thyroid peroxidase isoform a precursor [Homo sapiens]<div class="brieflinkpopdesc">gi|28558982|ref|NP_000538.3|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67ca1a1184f3725e5974647f">Tpo thyroid peroxidase [Mus musculus]</a>
|
||
<div class="ralinkpop offscreen_noflow">Tpo thyroid peroxidase [Mus musculus]<div class="brieflinkpopdesc">Gene ID:22018</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67ca1a0f84f3725e59745c35">thyroid peroxidase precursor [Mus musculus]</a>
|
||
<div class="ralinkpop offscreen_noflow">thyroid peroxidase precursor [Mus musculus]<div class="brieflinkpopdesc">gi|6678417|ref|NP_033443.1|</div></div>
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<div class="tertiary">Protein</div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67ca1a0ef4a390645e7a1cb0">PREDICTED: Mus musculus thyroid peroxidase (Tpo), transcript variant X1, mRNA</a>
|
||
<div class="ralinkpop offscreen_noflow">PREDICTED: Mus musculus thyroid peroxidase (Tpo), transcript variant X1, mRNA<div class="brieflinkpopdesc">gi|1907087299|ref|XM_011243856.3|</div></div>
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<div class="tertiary">Nucleotide</div>
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