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141 lines
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12 KiB
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<title>GEO DataSet Browser</title>
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<link rel="stylesheet" type="text/css" href="/core/extjs/ext-2.1/resources/css/ext-all.css" />
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<meta name="author" content="geo" />
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<meta name="keywords" content="GDS, GEO DataSets, GEO, Gene Expression Omnibus, NCBI, National Center for Biotechnology Information" />
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<meta name="description" content="Comparable experimental sample sets assembled from the Gene Expression Omnibus (GEO) repository." />
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<meta name="ncbi_app" content="gdsbrowser" /><meta name="ncbi_db" content="Gds" /><meta name="ncbi_term" content="GDS2971[ACCN]" /><meta name="ncbi_pagesize" content="20" /><meta name="ncbi_sortorder" content="" /><meta name="ncbi_pageno" content="1" /><meta name="ncbi_resultcount" content="1" /><meta name="ncbi_pdid" content="gdsbrowser" /><meta name="ncbi_sessionid" content="CE8B5AF87C7FFCB1_0191SID" />
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{"name":"GDSBrowser_L.GDSBrowser_C.GDSBrowserFooter","type":"Portlet","realname":"GDSBrowser_L.GDSBrowser_C.GDSBrowserFooter","shortname":"GDSBrowserFooter"}]}]};
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<meta name='referrer' content='origin-when-cross-origin'/><link type="text/css" rel="stylesheet" href="//static.pubmed.gov/portal/portal3rc.fcgi/4199987/css/4874/4955/3251144/186073/3251483/5182.css" /><script type="text/javascript">
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</script></head>
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<body>
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<div id="all">
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<div id="header">
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<div id="ncbi-image">
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<a href="/">
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<img width="145" height="66" border="0" alt="National Center for Biotechnology Information (NCBI)" src="/geo/img/ncbi_logo.gif" />
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</a>
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</div>
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<div id="gds-image">
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<a href="/sites/GDSbrowser/">
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<img alt="GEO DataSet Browser" src="/geo/img/GDSbrowser_logo.png" />
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</a>
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</div>
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<div id="geo-image">
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<a href="/geo/">
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<img border="0" alt="Gene Expression Omnibus (GEO)" src="/geo/img/geo_main.gif" />
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</a>
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</div>
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</div>
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<div id="main">
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<form enctype="application/x-www-form-urlencoded" name="GDSBrowserQuery" method="post" onsubmit="return false;" action="/sites/GDSbrowser" id="GDSBrowserQuery">
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<div id="query">
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<table summary="Query bar components">
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<div id="search_bar"><label for="term">Search for </label><input name="GDSBrowser_L.GDSBrowser_C.GDSBrowserQuery.Term" sid="1" type="text" id="term" value="GDS2971[ACCN]" size="45" /> <button name="GDSBrowser_L.GDSBrowser_C.GDSBrowserQuery.Search" sid="1" id="SearchButton" submit="yes">Search</button> <button name="GDSBrowser_L.GDSBrowser_C.GDSBrowserQuery.Clear" sid="1" id="ClearButton">Clear</button> <button name="GDSBrowser_L.GDSBrowser_C.GDSBrowserQuery.ShowAll" sid="1" id="ShowAll" submit="yes">Show All</button> <a class="button" href="/gds?term=gds[filter]">Advanced Search</a></div>
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<div id="details"><table id="gds_details" class="gds_panel" summary="GEO DataSet Details"><tr class="caption"><th colspan="5">
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DataSet Record GDS2971:
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<a href="/geoprofiles?term=GDS2971[ACCN]" target="_blank" class="button" title="View Expression Profiles">
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Expression Profiles
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</a><a href="#details" class="button" onclick="displayAnalysis(2971); return true" title="Data Analysis Tools">
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Data Analysis Tools
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</a><a href="#details" class="button" onclick="displaySamples(2971); return true" title="Sample Subsets">
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Sample Subsets
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</a></th></tr><tr><th scope="row" class="not_caption">
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Title:
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</th><td colspan="3">Hemiasterlin analog HTI-286 effect on docetaxel-resistant prostate cancer cell line</td><td id="detailsRightCol" rowspan="7"><fieldset><legend>Cluster Analysis</legend><a id="clusterLink" title="GDS2971 Cluster Analysis" href="/geo/gds/analyze/analyze.cgi?ID=GDS2971" target="_blank"><img alt="GDS2971 Cluster Image" width="80" height="80" src="/geo/img/UPGMA/UCorrelated/GDS2971i.png" /></a></fieldset><fieldset><legend>Download</legend><ul><li><a href="https://ftp.ncbi.nlm.nih.gov/geo/datasets/GDS2nnn/GDS2971/soft/GDS2971_full.soft.gz" title="Contains DataSet information, experiment variable subsets and expression value measurements (plain text, tab-delimited format)." class="dataset-soft-full">
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DataSet full SOFT file
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</a></li><li><a href="https://ftp.ncbi.nlm.nih.gov/geo/datasets/GDS2nnn/GDS2971/soft/GDS2971.soft.gz" title="Contains DataSet information, experiment variable subsets, expression value measurements and up-to-date gene annotation for the DataSet Platform (plain text, tab-delimited format)." class="dataset-soft">
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DataSet SOFT file
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</a></li><li><a href="https://ftp.ncbi.nlm.nih.gov/geo/series/GSE8nnn/GSE8325/soft/GSE8325_family.soft.gz" title="Contains the complete, original, submitter-supplied records that form the basis of this DataSet (plain text, tab-delimited format)." class="series-family-soft">
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Series family SOFT file
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</a></li><li><a href="https://ftp.ncbi.nlm.nih.gov/geo/series/GSE8nnn/GSE8325/miniml/GSE8325_family.xml.tgz" title="Contains the complete, original, submitter-supplied records that form the basis of this DataSet (XML format)." class="series-family-miniml">
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Series family MINiML file
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</a></li><li><a href="https://ftp.ncbi.nlm.nih.gov/geo/platforms/GPL3nnn/GPL3877/annot/GPL3877.annot.gz" title="Contains up-to-date gene annotation for the DataSet Platform (plain text, tab-delimited format)." class="annotation-soft">
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Annotation SOFT file
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</a></li></ul></fieldset></td></tr><tr><th scope="row" class="not_caption">
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Summary:
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</th><td colspan="3">Analysis of prostate cancer LNCaP cells treated with the chemotherapeutic agent docetaxel or the hemiasterlin analog HTI-286. Like docetaxel, HTI-286 disrupts microtubule dynamics. But unlike docetaxel, HT-286 exhibits reduced multidrug resistance.</td></tr><tr><th scope="row" class="not_caption">Organism:
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</th><td colspan="3" class="species"><a target="_blank" href="/Taxonomy/Browser/wwwtax.cgi?mode=Undef&lvl=0&srchmode=1&name=Homo%20sapiens">Homo sapiens</a></td></tr><tr><th scope="row" class="not_caption">
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Platform:
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</th><td colspan="3"><a href="/geo/query/acc.cgi?acc=GPL3877" target="_blank">
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GPL3877</a>:
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PRHU05-S1-0006 (PC Human Operon v2 21k) </td></tr><tr><th scope="row" class="not_caption">Citation:</th><td colspan="3"><div class="PubmedCitation"><ul><li><span class="authors">Hadaschik BA, Ettinger S, Sowery RD, Zoubeidi A et al. </span><span class="title">Targeting prostate cancer with HTI-286, a synthetic analog of the marine sponge product hemiasterlin. </span><span class="source">Int J Cancer</span> 2008 May 15;122(10):2368-76. PMID: <a title="Link to PubMed record" href="https://www.ncbi.nlm.nih.gov/pubmed/18240145">18240145</a></li></ul></div></td></tr><tr><th scope="row" class="not_caption">
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Reference Series:
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</th><td><a href="/geo/query/acc.cgi?acc=GSE8325" target="_blank">
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GSE8325</a></td><th id="samp-cnt" class="not_caption">
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Sample count:
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</th><td>12</td></tr><tr><th scope="row" class="not_caption">
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Value type:
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</th><td>log2 ratio</td><th id="series-pub" class="not_caption">
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Series published:
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</th><td>2007/06/29</td></tr></table><div id="divExtra"></div></div>
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</div>
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<div id="footer">
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||
<ul>
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<li class="first"><a href="https://www.nlm.nih.gov/">NLM</a></li>
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<li><a href="https://www.nih.gov/">NIH</a></li>
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<li><a href="mailto:geo@ncbi.nlm.nih.gov">GEO Help</a></li>
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<li><a href="/geo/info/disclaimer.html">Disclaimer</a></li>
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<li><a href="https://www.nlm.nih.gov/accessibility.html">Accessibility</a></li>
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</ul>
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</div>
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</div>
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<script type="text/javascript" src="/portal/portal3rc.fcgi/rlib/js/InstrumentOmnitureBaseJS/InstrumentNCBIBaseJS/InstrumentPageStarterJS.js"></script>
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<script type="text/javascript">
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jQuery.getScript("/core/alerts/alerts.js", function () {
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galert(['div.nav_and_browser', 'div.header', '#universal_header', '#header'])
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</script>
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<!-- CE8B5AF87C7FFCB1_0191SID /projects/GEO/GDSBrowser@1.51 portal106 v4.1.r689238 Tue, Oct 22 2024 16:10:51 -->
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<script type='text/javascript' src='/portal/js/portal.js'></script><script type="text/javascript" src="//static.pubmed.gov/portal/portal3rc.fcgi/4199987/js/4962/4093349/4807/3867120/3251151.js" snapshot="GDSbrowser"></script></body>
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</html> |