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123 KiB
XML
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<div><div class="rprt"><div class="rprtnum nohighlight"><span>1.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC5068859/figure/fig8/" ref="ordinalpos=1&ncbi_uid=9759907&link_uid=PMC5068859" href="/pmc/articles/PMC5068859/"><img src="/pmc/articles/instance/5068859/bin/737fig8.gif" src-large="/pmc/articles/instance/5068859/bin/737fig8.jpg" alt="Figure 8" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC5068859/" ref="ordinalpos=1&ncbi_uid=9759907&link_uid=PMC5068859" image-link="/pmc/articles/PMC5068859/figure/fig8/" class="imagepopup">Figure 8. From: Commonalities in Development of Pure Breeds and Population Isolates Revealed in the Genome of the Sardinian Fonni's <span class="highlight" style="background-color:">Dog</span>. </a></p><div class="supp"><p class="details"><div>(A) Admixture predictions by three computational algorithms. TreeMix three_pop analysis (green arrow) identified Fonni’s <span class="highlight" style="background-color:">Dog</span> contribution to the Portuguese Water <span class="highlight" style="background-color:">Dog</span>/Cane Paratore clade at 17.43% with <i>P</i> = 0.00723. ANGSD (red dashed line) calculated significant values of <i>D</i>(<i>O</i>, Fonni’s <span class="highlight" style="background-color:">Dog</span>; Komondor, Cane Corso) = 0.039, <i>Z</i> = 4.366; <i>D</i>(<i>O</i>, Komondor; Fonni’s <span class="highlight" style="background-color:">Dog</span>, Cane Corso) = 0.031, <i>Z</i> = 3.920; <i>D</i>(<i>O</i>, Fonni’s <span class="highlight" style="background-color:">Dog</span>; Saluki, Cane Corso) = 0.033, <i>Z</i> = 3.893; <i>D</i>(<i>O</i>, Saluki; Fonni’s <span class="highlight" style="background-color:">Dog</span>, Cane Corso) = 0.040, <i>Z</i> = 5.075. AdmixTools (blue dashed line) supports the findings of TreeMix with significant <i>D</i>-statistic values for Fonni’s <span class="highlight" style="background-color:">Dog</span> and Portuguese Water <span class="highlight" style="background-color:">Dog</span> of <i>D</i>(<i>O</i>, Portuguese Water <span class="highlight" style="background-color:">Dog</span>; Fonni’s <span class="highlight" style="background-color:">Dog</span>, <i>X</i>) = −0.0139 to −0.1287, <i>Z</i> = −3.737 to −25.274; <i>D</i>(<i>O</i>, Fonni’s <span class="highlight" style="background-color:">Dog</span>; Portuguese Water <span class="highlight" style="background-color:">Dog</span>, <i>X</i>) = −0.0127 to −0.1309, <i>Z</i> = −3.078 to −25.797; <i>D</i>(<i>O</i>, Fonni’s <span class="highlight" style="background-color:">Dog</span>; <i>X</i>, Portuguese Water <span class="highlight" style="background-color:">Dog</span>) = 0.0100–0.0767, <i>Z</i> = 3.016–22.189; Cane Paratore of <i>D</i>(<i>O</i>, Cane Paratore; Fonni’s <span class="highlight" style="background-color:">Dog</span>, <i>X</i>) = −0.0104 to −0.1317, <i>Z</i> = −3.108 to −26.025; <i>D</i>(<i>O</i>, Fonni’s <span class="highlight" style="background-color:">Dog</span>; Cane Paratore, <i>X</i>) = −0.0096 to −0.1289, <i>Z</i> = −3.055 to −25.805; <i>D</i>(<i>O</i>, Fonni’s <span class="highlight" style="background-color:">Dog</span>; <i>X</i>, Cane Paratore) = 0.0104–0.0811, <i>Z</i> = 3.643–22.974; Komondor of <i>D</i>(<i>O</i>, Fonni’s <span class="highlight" style="background-color:">Dog</span>; Komondor, <i>X</i>) = −0.0116 to −0.1123; <i>D</i>(<i>O</i>, Fonni’s <span class="highlight" style="background-color:">Dog</span>; <i>X</i>, Komondor) = 0.0116–0.1280, <i>Z</i> = 3.142–25.720; and Saluki of <i>D</i>(Saluki, <i>X</i>; Fonni’s <span class="highlight" style="background-color:">Dog</span>, <i>Y</i>) = 0.007–0.131, <i>Z</i> = 3.047–29.352. TreeMix predicted phylogenies with (B) 1 or(C) 25 allowed introgression events, and corresponding standard error residuals for (D) 1 and (E) 25 introgressions.</div></p></div><div class="aux"><div class="resc">Dayna L. Dreger, et al. Genetics. 2016 Oct;204(2):737-755.</div><p class="links"><a class="dblinks" href="/pubmed/27519604" ref="ordinalpos=1&ncbi_uid=9759907&link_uid=27519604">Citation</a><a class="dblinks" href="/pmc/articles/PMC5068859/" ref="ordinalpos=1&ncbi_uid=9759907&link_uid=PMC5068859">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>2.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC10087160/figure/cea14216-fig-0004/" ref="ordinalpos=2&ncbi_uid=27719207&link_uid=PMC10087160" href="/pmc/articles/PMC10087160/"><img src="/pmc/articles/instance/10087160/bin/CEA-53-88-g004.gif" src-large="/pmc/articles/instance/10087160/bin/CEA-53-88-g004.jpg" alt="FIGURE 4" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC10087160/" ref="ordinalpos=2&ncbi_uid=27719207&link_uid=PMC10087160" image-link="/pmc/articles/PMC10087160/figure/cea14216-fig-0004/" class="imagepopup">FIGURE 4. From: Sensitization to molecular <span class="highlight" style="background-color:">dog</span> allergens in an adult population: Results from the West Sweden Asthma Study. </a></p><div class="supp"><p class="details"><div>Current <span class="highlight" style="background-color:">dog</span> owners show increased levels of sIgE to Can f 3 and Can f 5. Venn diagram of the sIgE positivity for lipocalins, albumin and prostatic kallikrein among non‐current <span class="highlight" style="background-color:">dog</span> owners (A); among current <span class="highlight" style="background-color:">dog</span> owners (B). Comparison of median sIgE levels to each <span class="highlight" style="background-color:">dog</span> allergen component by current <span class="highlight" style="background-color:">dog</span> ownership (current <span class="highlight" style="background-color:">dog</span> owners <i>n</i> = 46, non‐current <span class="highlight" style="background-color:">dog</span> owners, <i>n</i> = 267) in all study group (C). Comparison of median sIgE levels to each <span class="highlight" style="background-color:">dog</span> allergen component by current <span class="highlight" style="background-color:">dog</span> ownership (current <span class="highlight" style="background-color:">dog</span> owners <i>n</i> = 35, non‐current <span class="highlight" style="background-color:">dog</span> owners, <i>n</i> = 183) among subjects sensitized to at least one <span class="highlight" style="background-color:">dog</span> allergen component (D). %, percentage of those sensitized to respective allergen components within each group. D, current <span class="highlight" style="background-color:">dog</span> ownership; e5, <span class="highlight" style="background-color:">dog</span> dander immunoglobulin E; sIgE, specific immunoglobulin E. In (C,D) data are presented as median, and whiskers indicate the minimum and maximum values. *Of note, one person can be sensitized to several <span class="highlight" style="background-color:">dog</span> allergen components and thus, the same person can be included in several of the groups.</div></p></div><div class="aux"><div class="resc">Saliha Selin Özuygur Ermis, et al. Clin Exp Allergy. 2023 Jan;53(1):88-104.</div><p class="links"><a class="dblinks" href="/pubmed/35984703" ref="ordinalpos=2&ncbi_uid=27719207&link_uid=35984703">Citation</a><a class="dblinks" href="/pmc/articles/PMC10087160/" ref="ordinalpos=2&ncbi_uid=27719207&link_uid=PMC10087160">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>3.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC10370749/figure/pone.0288137.g002/" ref="ordinalpos=3&ncbi_uid=28767382&link_uid=PMC10370749" href="/pmc/articles/PMC10370749/"><img src="/pmc/articles/instance/10370749/bin/pone.0288137.g002.gif" src-large="/pmc/articles/instance/10370749/bin/pone.0288137.g002.jpg" alt="Fig 2" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC10370749/" ref="ordinalpos=3&ncbi_uid=28767382&link_uid=PMC10370749" image-link="/pmc/articles/PMC10370749/figure/pone.0288137.g002/" class="imagepopup">Fig 2. Emotion ratings for <span class="highlight" style="background-color:">dog</span> image categories (Happy <span class="highlight" style="background-color:">Dog</span>, Aggressive <span class="highlight" style="background-color:">Dog</span>, Neutral <span class="highlight" style="background-color:">Dog</span>) between age groups.. From: Matters of development and experience: Evaluation of <span class="highlight" style="background-color:">dog</span> and human emotional expressions by children and adults. </a></p><div class="supp"><p class="details"><div>Ratings are displayed separately for participants with experience of living in the same household with a <span class="highlight" style="background-color:">dog</span> (with <span class="highlight" style="background-color:">dog</span> experience) or without such experiences (no <span class="highlight" style="background-color:">dog</span> experience). Value 0 means that participants have answered incorrectly when asked what kind of emotion there is in the image and value 1 that they have answered correctly. Statistically significant differences between the participant groups are represented by asterisks (**p<0.01 and *p<0.05).</div></p></div><div class="aux"><div class="resc">Heini Törnqvist, et al. PLoS One. 2023;18(7):e0288137.</div><p class="links"><a class="dblinks" href="/pubmed/37494304" ref="ordinalpos=3&ncbi_uid=28767382&link_uid=37494304">Citation</a><a class="dblinks" href="/pmc/articles/PMC10370749/" ref="ordinalpos=3&ncbi_uid=28767382&link_uid=PMC10370749">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>4.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC3986229/figure/pone-0094732-g004/" ref="ordinalpos=4&ncbi_uid=6027217&link_uid=PMC3986229" href="/pmc/articles/PMC3986229/"><img src="/pmc/articles/instance/3986229/bin/pone.0094732.g004.gif" src-large="/pmc/articles/instance/3986229/bin/pone.0094732.g004.jpg" alt="Figure 4" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC3986229/" ref="ordinalpos=4&ncbi_uid=6027217&link_uid=PMC3986229" image-link="/pmc/articles/PMC3986229/figure/pone-0094732-g004/" class="imagepopup">Figure 4. Regulation of NR4A1 mRNA in normal, vehicle and CI treated <span class="highlight" style="background-color:">dog</span> LV I/R and non-I/R regions by microarray and RT-PCR.. From: Chymase Mediates Injury and Mitochondrial Damage in Cardiomyocytes during Acute Ischemia/Reperfusion in the <span class="highlight" style="background-color:">Dog</span>. </a></p><div class="supp"><p class="details"><div>Table (a) demonstrates Genesping GX.11 fold change from microarray and p value for mRNA intensity value of NR4A1 and ATF3 in normal, I/R and non-I/R vehicle- and CI-treated <span class="highlight" style="background-color:">dog</span> LV. Panel b demonstrates real-time RT-PCR validation of NR4A1 (left) and ATF3 (right) mRNA in normal, I/R and non-I/R vehicle- (Veh-nIR) and CI-treated <span class="highlight" style="background-color:">dog</span> LV. Normal <span class="highlight" style="background-color:">dog</span>, n = 5; Veh <span class="highlight" style="background-color:">dog</span>, n = 6; CI <span class="highlight" style="background-color:">dog</span>, n = 6.</div></p></div><div class="aux"><div class="resc">Junying Zheng, et al. PLoS One. 2014;9(4):e94732.</div><p class="links"><a class="dblinks" href="/pubmed/24733352" ref="ordinalpos=4&ncbi_uid=6027217&link_uid=24733352">Citation</a><a class="dblinks" href="/pmc/articles/PMC3986229/" ref="ordinalpos=4&ncbi_uid=6027217&link_uid=PMC3986229">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>5.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC5710885/figure/F6/" ref="ordinalpos=5&ncbi_uid=11675812&link_uid=PMC5710885" href="/pmc/articles/PMC5710885/"><img src="/pmc/articles/instance/5710885/bin/oncotarget-08-90796-g006.gif" src-large="/pmc/articles/instance/5710885/bin/oncotarget-08-90796-g006.jpg" alt="Figure 6" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC5710885/" ref="ordinalpos=5&ncbi_uid=11675812&link_uid=PMC5710885" image-link="/pmc/articles/PMC5710885/figure/F6/" class="imagepopup">Figure 6. IgE binding studies of B cell peptides of Can f 6 with the <span class="highlight" style="background-color:">dog</span> allergic children’s sera and NHS by ELISA. From: Canis familiaris allergen Can f 6: expression, purification and analysis of B-cell epitopes in Chinese <span class="highlight" style="background-color:">dog</span> allergic children. </a></p><div class="supp"><p class="details"><div><b>A.</b> The results of <span class="highlight" style="background-color:">dog</span> allergic children’s sera compared to the normal human serum (NHS) of the first B cell epitope (P1). <b>B.</b> The results of <span class="highlight" style="background-color:">dog</span> allergic children’s sera compared to NHS of P2. <b>C.</b> The results of <span class="highlight" style="background-color:">dog</span> allergic children’s sera compared to NHS of P3. <b>D.</b> The results of <span class="highlight" style="background-color:">dog</span> allergic children’s sera compared to NHS of P4. <b>E.</b> The results of <span class="highlight" style="background-color:">dog</span> allergic children’s sera compared to NHS of P5. <b>F.</b> The results of <span class="highlight" style="background-color:">dog</span> allergic children’s sera compared to NHS of an unrelevant control peptide (P6) from the Can f 6 sequence.</div></p></div><div class="aux"><div class="resc">Yu-Jie Wang, et al. Oncotarget. 2017 Oct 31;8(53):90796-90807.</div><p class="links"><a class="dblinks" href="/pubmed/29207604" ref="ordinalpos=5&ncbi_uid=11675812&link_uid=29207604">Citation</a><a class="dblinks" href="/pmc/articles/PMC5710885/" ref="ordinalpos=5&ncbi_uid=11675812&link_uid=PMC5710885">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>6.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC8614278/figure/animals-11-03136-f001/" ref="ordinalpos=6&ncbi_uid=22097192&link_uid=PMC8614278" href="/pmc/articles/PMC8614278/"><img src="/pmc/articles/instance/8614278/bin/animals-11-03136-g001.gif" src-large="/pmc/articles/instance/8614278/bin/animals-11-03136-g001.jpg" alt="Figure 1" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC8614278/" ref="ordinalpos=6&ncbi_uid=22097192&link_uid=PMC8614278" image-link="/pmc/articles/PMC8614278/figure/animals-11-03136-f001/" class="imagepopup">Figure 1. From: Insight into the Candidate Genes and Enriched Pathways Associated with Height, Length, Length to Height Ratio and Body-Weight of Korean Indigenous Breed, Jindo <span class="highlight" style="background-color:">Dog</span> Using Gene Set Enrichment-Based GWAS Analysis. </a></p><div class="supp"><p class="details"><div>The phenotypic variation of Jindo <span class="highlight" style="background-color:">dog</span>. (<b>A</b>). Male Jindo <span class="highlight" style="background-color:">dog</span> with height 35.5 cm, length 38.5 cm, LHR 114.1, (<b>B</b>). Female Jindo <span class="highlight" style="background-color:">dog</span> with height 35 cm, length 40 cm, LHR 114.3, (<b>C</b>). Female Jindo <span class="highlight" style="background-color:">dog</span> with height 42 cm, length 43 cm, LHR 102.4, (<b>D</b>). Female Jindo <span class="highlight" style="background-color:">dog</span> with height 47 cm, length 48 cm, LHR 102.1, (<b>E</b>). Female Jindo <span class="highlight" style="background-color:">dog</span> with height 50 cm, length 54 cm, LHR 108, (<b>F</b>). Female Jindo <span class="highlight" style="background-color:">dog</span> with height 51.5 cm, length 54.4 cm, LHR 105.6, (<b>G</b>). Female Jindo <span class="highlight" style="background-color:">dog</span> with height 49 cm, length 52 cm, LHR 106.1, (<b>H</b>). Male Jindo <span class="highlight" style="background-color:">dog</span> with height 52.0 cm, length 55.5 cm, LHR 106.7.</div></p></div><div class="aux"><div class="resc">Sunirmal Sheet, et al. Animals (Basel). 2021 Nov;11(11):3136.</div><p class="links"><a class="dblinks" href="/pubmed/34827868" ref="ordinalpos=6&ncbi_uid=22097192&link_uid=34827868">Citation</a><a class="dblinks" href="/pmc/articles/PMC8614278/" ref="ordinalpos=6&ncbi_uid=22097192&link_uid=PMC8614278">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>7.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC9223617/figure/pntd.0010469.g003/" ref="ordinalpos=7&ncbi_uid=24413857&link_uid=PMC9223617" href="/pmc/articles/PMC9223617/"><img src="/pmc/articles/instance/9223617/bin/pntd.0010469.g003.gif" src-large="/pmc/articles/instance/9223617/bin/pntd.0010469.g003.jpg" alt="Fig 3" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC9223617/" ref="ordinalpos=7&ncbi_uid=24413857&link_uid=PMC9223617" image-link="/pmc/articles/PMC9223617/figure/pntd.0010469.g003/" class="imagepopup">Fig 3. Comparison of Waiwai <span class="highlight" style="background-color:">dog</span> shelves used in the past and current Waiwai <span class="highlight" style="background-color:">dog</span> houses.. From: A mixed-methods approach to understanding domestic <span class="highlight" style="background-color:">dog</span> health and disease transmission risk in an indigenous reserve in Guyana, South America. </a></p><div class="supp"><p class="details"><div>A) View of the interior of a communal Waiwai house in Konashen, Guyana circa 1955, showing a <span class="highlight" style="background-color:">dog</span> leashed on a <span class="highlight" style="background-color:">dog</span> shelf on the left. Scanned black and white negative. Interior with hammocks, three people and a <span class="highlight" style="background-color:">dog</span>. Negative of slide 2. Object no: ARC/GUP/004/003 Horniman Museum and Gardens. B) <span class="highlight" style="background-color:">Dog</span> house in Masakenari Village, Guyana in 2019.</div></p></div><div class="aux"><div class="resc">Marissa S. Milstein, et al. PLoS Negl Trop Dis. 2022 Jun;16(6):e0010469.</div><p class="links"><a class="dblinks" href="/pubmed/35687596" ref="ordinalpos=7&ncbi_uid=24413857&link_uid=35687596">Citation</a><a class="dblinks" href="/pmc/articles/PMC9223617/" ref="ordinalpos=7&ncbi_uid=24413857&link_uid=PMC9223617">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>8.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC2270093/figure/fig03/" ref="ordinalpos=8&ncbi_uid=1343499&link_uid=PMC2270093" href="/pmc/articles/PMC2270093/"><img src="/pmc/articles/instance/2270093/bin/tjp0527-0467-f3.gif" src-large="/pmc/articles/instance/2270093/bin/tjp0527-0467-f3.jpg" alt="Figure 3" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC2270093/" ref="ordinalpos=8&ncbi_uid=1343499&link_uid=PMC2270093" image-link="/pmc/articles/PMC2270093/figure/fig03/" class="imagepopup">Figure 3. Protein studies in <span class="highlight" style="background-color:">dog</span> atrium. From: Molecular evidence for a role of Shaw (Kv3) potassium channel subunits in potassium currents of <span class="highlight" style="background-color:">dog</span> atrium. </a></p><div class="supp"><p class="details"><div><i>A,</i> Western blots of membrane proteins prepared from <span class="highlight" style="background-color:">dog</span> atrium (lane 1, DA1) and isolated <span class="highlight" style="background-color:">dog</span> atrial myocytes (lane 2, DA2) probed with a Kv3.1 antibody. Lane 3, <span class="highlight" style="background-color:">dog</span> atrial membrane preparation after pre-incubation of antibody with Kv3.1 peptide (Pre-inc). <i>B,</i> Western blots with Kv1.5 antibody obtained with human atrial (HA) and <span class="highlight" style="background-color:">dog</span> atrial (DA) tissues.</div></p></div><div class="aux"><div class="resc">Lixia Yue, et al. J Physiol. 2000 Sep 15;527(Pt 3):467-478.</div><p class="links"><a class="dblinks" href="/pubmed/10990534" ref="ordinalpos=8&ncbi_uid=1343499&link_uid=10990534">Citation</a><a class="dblinks" href="/pmc/articles/PMC2270093/" ref="ordinalpos=8&ncbi_uid=1343499&link_uid=PMC2270093">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>9.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC11572942/figure/F1/" ref="ordinalpos=9&ncbi_uid=35713146&link_uid=PMC11572942" href="/pmc/articles/PMC11572942/"><img src="/pmc/articles/instance/11572942/bin/OC-AAPJ240072F001.gif" src-large="/pmc/articles/instance/11572942/bin/OC-AAPJ240072F001.jpg" alt="Figure 1." /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC11572942/" ref="ordinalpos=9&ncbi_uid=35713146&link_uid=PMC11572942" image-link="/pmc/articles/PMC11572942/figure/F1/" class="imagepopup">Figure 1. From: Do commercial <span class="highlight" style="background-color:">dog</span> extracts cross-react with Felis domesticus allergen 1. </a></p><div class="supp"><p class="details"><div>AP <span class="highlight" style="background-color:">dog</span>, CV <span class="highlight" style="background-color:">dog</span>, and UF <span class="highlight" style="background-color:">dog</span> SDS-PAGE. SDS-PAGE = sodium dodecyl-sulfate polyacrylamide gel electrophoresis; AP = acetone precipitated <span class="highlight" style="background-color:">dog</span> hair and dander extract; CV = conventional <span class="highlight" style="background-color:">dog</span> hair and dander extract; UP = ultrafiltered <span class="highlight" style="background-color:">dog</span> hair and dander extract; MW = molecular weight.</div></p></div><div class="aux"><div class="resc">Tasha Hellu, et al. Allergy Asthma Proc. 2024 Nov;45(6):447-452.</div><p class="links"><a class="dblinks" href="/pubmed/39517074" ref="ordinalpos=9&ncbi_uid=35713146&link_uid=39517074">Citation</a><a class="dblinks" href="/pmc/articles/PMC11572942/" ref="ordinalpos=9&ncbi_uid=35713146&link_uid=PMC11572942">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>10.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC7117499/figure/fig3/" ref="ordinalpos=10&ncbi_uid=16762522&link_uid=PMC7117499" href="/pmc/articles/PMC7117499/"><img src="/pmc/articles/instance/7117499/bin/gr3.gif" src-large="/pmc/articles/instance/7117499/bin/gr3.jpg" alt="Fig. 3" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC7117499/" ref="ordinalpos=10&ncbi_uid=16762522&link_uid=PMC7117499" image-link="/pmc/articles/PMC7117499/figure/fig3/" class="imagepopup">Fig. 3. From: Genetic diversity of Hungarian canine distemper virus strains. </a></p><div class="supp"><p class="details"><div>Phylogenetic tree constructed upon the complete nucleotide sequences of the H genes of representative CDVs and the selected Hungarian strains. The code, accession number and provenience for the sequences used in the present study are as follow: <span class="highlight" style="background-color:">Dog</span> 98-002 Jpn (AB025270, Japan), <span class="highlight" style="background-color:">Dog</span> KDK1 Jpn (AB025271, Japan), <span class="highlight" style="background-color:">Dog</span> 26D Jpn (AB040766, Japan), <span class="highlight" style="background-color:">Dog</span> Hm3 Jpn (AB040767, Japan), <span class="highlight" style="background-color:">Dog</span> Hm6 Jpn (AB040768, Japan), <span class="highlight" style="background-color:">Dog</span> 00Lm Jpn (AB212730, Japan), <span class="highlight" style="background-color:">Dog</span> P945 Jpn (AB212964, Japan), <span class="highlight" style="background-color:">Dog</span> S124C Jpn (AB212965, Japan), <span class="highlight" style="background-color:">Dog</span> A75/17 USA (AF164967, USA), <span class="highlight" style="background-color:">Dog</span> Chn (AF172411, China), Giant Panda Chn (AF178038, China), Lesser Panda Chn (AF178039, China), Snyder Hill (AF259552, Germany), Onderstepoort (AF378705, South Africa), <span class="highlight" style="background-color:">Dog</span> DK91 Dnk (AF478544, Denmark), <span class="highlight" style="background-color:">Dog</span> Trk (AY093674, Turkey), <span class="highlight" style="background-color:">Dog</span> 5804 Ger (AY386315, Germany), <span class="highlight" style="background-color:">Dog</span> TN Chn (AY390347, China), Racoon 00-2601 USA (AY438597, USA), Racoon 01-2676 USA (AY498692, USA), Racoon 01-2641 USA (AY526496, USA), Racoon 01-2689 USA (AY649446, USA), <span class="highlight" style="background-color:">Dog</span> 18133 USA (AY964108, USA), <span class="highlight" style="background-color:">Dog</span> 19876 USA (AY964110, USA), <span class="highlight" style="background-color:">Dog</span> 25259 USA (AY964114, USA), <span class="highlight" style="background-color:">Dog</span> NTU 1 Jpn (DQ191175, Japan), <span class="highlight" style="background-color:">Dog</span> NTU Jpn (DQ191765, Japan), <span class="highlight" style="background-color:">Dog</span> 324-03 Ita (DQ494317, Italy), <span class="highlight" style="background-color:">Dog</span> 265 Ita (DQ494318, Italy), Ferret Ger (X84999, Germany), Convac (Z35493, Denmark), Mink Dnk (Z47759, Denmark), <span class="highlight" style="background-color:">Dog</span> Dnk (Z47761, Denmark), Black Leopard USA (Z47763, USA), Javelina USA (Z47764, USA), Chinese Leopard USA (Z54156, USA), <span class="highlight" style="background-color:">Dog</span> 404 Ger (Z77671, Germany), <span class="highlight" style="background-color:">Dog</span> Grn (Z47760, Greenland), Seal PDV2 Rus (X84998, Russia), <span class="highlight" style="background-color:">Dog</span> 179-94 Ita (DQ226087, Italy), <span class="highlight" style="background-color:">Dog</span> Yanaka Jpn (D85755, Japan), <span class="highlight" style="background-color:">Dog</span> Hamamatsu Jpn (D85754, Japan).</div></p></div><div class="aux"><div class="resc">Zoltán Demeter, et al. Vet Microbiol. 2007 Jun 21;122(3):258-269.</div><p class="links"><a class="dblinks" href="/pubmed/17350769" ref="ordinalpos=10&ncbi_uid=16762522&link_uid=17350769">Citation</a><a class="dblinks" href="/pmc/articles/PMC7117499/" ref="ordinalpos=10&ncbi_uid=16762522&link_uid=PMC7117499">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>11.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC524033/figure/F6/" ref="ordinalpos=11&ncbi_uid=544269&link_uid=PMC524033" href="/pmc/articles/PMC524033/"><img src="/pmc/articles/instance/524033/bin/1743-422X-1-2-6.gif" src-large="/pmc/articles/instance/524033/bin/1743-422X-1-2-6.jpg" alt="Figure 6" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC524033/" ref="ordinalpos=11&ncbi_uid=544269&link_uid=PMC524033" image-link="/pmc/articles/PMC524033/figure/F6/" class="imagepopup">Figure 6. From: Genetically distant American Canine distemper virus lineages have recently caused epizootics with somewhat different characteristics in raccoons living around a large suburban zoo in the USA. </a></p><div class="supp"><p class="details"><div><i>H</i>-gene 70% majority rule parsimony consensus tree. Arrows or boxes demarcate locations of viruses from this study. GenBank accession numbers are: (1) CDV 00-2601 (Illinois raccoon, Table 3); (2) Chinese leopard (Z54156); (3) 01-2641 (Illinois raccoon, Table 3); (4) black leopard (Z47763); (5) black panther (Z54166); (6 – 8, Illinois raccoons, Table 3); (9) raccoon (Z47765); (10) A75/17 (AF164967); (11) <span class="highlight" style="background-color:">dog</span> (USA) (Z47762); (12) javelina (Z47764); (13) raccoon <span class="highlight" style="background-color:">dog</span> Tanu (AB016776); (14) <span class="highlight" style="background-color:">dog</span> (Taiwan) (AY378091); (15) <span class="highlight" style="background-color:">dog</span> Hamam (D85754); (16) <span class="highlight" style="background-color:">dog</span> KDK1 (AB025271); (17) <span class="highlight" style="background-color:">dog</span> Ueno (D85753); (18) <span class="highlight" style="background-color:">dog</span> Yanaka (D85755); (19) giant panda (AF178038); (20) <span class="highlight" style="background-color:">dog</span> 5804 (AY386315); (21) <span class="highlight" style="background-color:">dog</span> Denmark (Z47761); (22) <span class="highlight" style="background-color:">dog</span> 91A (AF478544); (23) <span class="highlight" style="background-color:">dog</span> isolate A (AF478543); (24) <span class="highlight" style="background-color:">dog</span> 91B (AF478546); (25) <span class="highlight" style="background-color:">dog</span> 91C (AF478548); (26) <span class="highlight" style="background-color:">dog</span> 91D (AF478550); (27) <span class="highlight" style="background-color:">dog</span> isolate C (AF478547); (28) <span class="highlight" style="background-color:">dog</span> isolate B (AF478545); (29) <span class="highlight" style="background-color:">dog</span> isolate D (AF478549); (30) <span class="highlight" style="background-color:">dog</span> isolate 2544 (Z77672); (31) <span class="highlight" style="background-color:">dog</span> isolate 404 (Z77671); (32) <span class="highlight" style="background-color:">dog</span> isolate 4513 (Z77673); (33) <span class="highlight" style="background-color:">dog</span> (Turkey) (AY093674); (34) ferret (X84999); (35) mink (Z47759); (36) lesser panda (AF178039); (37) Siberian seal (X84998); (38) <span class="highlight" style="background-color:">dog</span> (China) (AF172411); (39) <span class="highlight" style="background-color:">dog</span> (Greenland) (Z47760); (40) <span class="highlight" style="background-color:">dog</span> 26D (AB040766); (41) <span class="highlight" style="background-color:">dog</span> 5B (AY297453); (42) <span class="highlight" style="background-color:">dog</span> 5VD (AY297454); (43) <span class="highlight" style="background-color:">dog</span> 98-002 (AB025270); (44) <span class="highlight" style="background-color:">dog</span> HM-3 (AB040767); (45) <span class="highlight" style="background-color:">dog</span> HM-6 (AB040768); (46 – 54, Illinois raccoons, Table 3), (55) Snyder Hill (AF259552); (56) Onderstepoort (AF378705); (57) PDV-1 (AF479274).</div></p></div><div class="aux"><div class="resc">John A Lednicky, et al. Virol J. 2004;1:2-2.</div><p class="links"><a class="dblinks" href="/pubmed/15507154" ref="ordinalpos=11&ncbi_uid=544269&link_uid=15507154">Citation</a><a class="dblinks" href="/pmc/articles/PMC524033/" ref="ordinalpos=11&ncbi_uid=544269&link_uid=PMC524033">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>12.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC3464546/figure/F2/" ref="ordinalpos=12&ncbi_uid=5371327&link_uid=PMC3464546" href="/pmc/articles/PMC3464546/"><img src="/pmc/articles/instance/3464546/bin/zbc0431226320002.gif" src-large="/pmc/articles/instance/3464546/bin/zbc0431226320002.jpg" alt="FIGURE 2." /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC3464546/" ref="ordinalpos=12&ncbi_uid=5371327&link_uid=PMC3464546" image-link="/pmc/articles/PMC3464546/figure/F2/" class="imagepopup">FIGURE 2. From: Serine 123 Phosphorylation Modulates p21 Protein Stability and Activity by Suppressing Ubiquitin-independent Proteasomal Degradation. </a></p><div class="supp"><p class="details"><div><b>Serine 123 phosphorylation is required for expression of the phosphorylated p21 isoform.</b> <i>A</i>, sequence similarity between human and <span class="highlight" style="background-color:">dog</span> p21. <i>Shaded areas</i> indicate the regions for replacing <span class="highlight" style="background-color:">dog</span> p21 with that of human p21 and vice versa. <i>B</i>, schematic representation of various <span class="highlight" style="background-color:">dog</span> and human p21 mutants. <i>C</i>, region, from amino acid 117 to 126, in <span class="highlight" style="background-color:">dog</span> p21, required for expression of two <span class="highlight" style="background-color:">dog</span> p21 isoforms. Three micrograms of pcDNA3 vectors that express HA-tagged wild-type <span class="highlight" style="background-color:">dog</span> p21, <span class="highlight" style="background-color:">dog</span> p21(Hu 38–74), <span class="highlight" style="background-color:">dog</span> p21(Hu 74–83), <span class="highlight" style="background-color:">dog</span> p21(Hu 84–93), <span class="highlight" style="background-color:">dog</span> p21(Hu 107–116), <span class="highlight" style="background-color:">dog</span> p21(Hu 117–126), and <span class="highlight" style="background-color:">dog</span> p21(Hu 127–136) was transfected into Cf2Th cells for 24 h followed by Western blot analysis to determine the levels of p21 proteins, actin, and GAPDH. <i>D</i>, 3 μg of pCDNA3 vectors that express HA-tagged wild-type <span class="highlight" style="background-color:">dog</span> p21, wild-type human p21, human p21(<span class="highlight" style="background-color:">Dog</span> 117–136), human p21(<span class="highlight" style="background-color:">Dog</span> 117–126), human p21(R122H), and human p21(G124P) transfected into 293T cells for 24 h, followed by Western blot analysis to determine the levels of p21 proteins, actin, and GAPDH. <i>E</i>, Cf2Th cells transiently transfected with pcDNA3 vectors expressing human p21(<span class="highlight" style="background-color:">Dog</span> 117–136), human p21(<span class="highlight" style="background-color:">Dog</span> 117–126), human p21(R122H), and human p21(G124P) for 24 h. The cell lysates were treated with or without λ phosphatase (300 units) for 30 min, followed by Western blot analysis to determine the level of p21 proteins, actin, and GAPDH. <i>F</i>, proline at 124 requirement for expression of two <span class="highlight" style="background-color:">dog</span> p21 isoforms. Three micrograms of pcDNA3 vectors that express HA-tagged wild-type <span class="highlight" style="background-color:">dog</span> p21, <span class="highlight" style="background-color:">dog</span> p21(Hu 117–126), <span class="highlight" style="background-color:">dog</span> p21(L120V), <span class="highlight" style="background-color:">dog</span> p21(H122R), <span class="highlight" style="background-color:">dog</span> p21(P124G), and <span class="highlight" style="background-color:">dog</span> p21(R126Q) was transfected into Cf2Th cells for 24 h followed by Western blot analysis to determine the levels of p21 proteins, actin, and GAPDH. <i>G</i>, serine 123 phosphorylation responsibility for expression of two <span class="highlight" style="background-color:">dog</span> p21 isoforms. Three micrograms of pcDNA3 vectors that express HA-tagged wild-type <span class="highlight" style="background-color:">dog</span> p21, <span class="highlight" style="background-color:">dog</span> p21(Hu 117–126), <span class="highlight" style="background-color:">dog</span> p21(S123A), and <span class="highlight" style="background-color:">dog</span> p21(S123D) was transfected into Cf2Th cells for 24 h followed by Western blot analysis to determine the levels of p21 proteins, actin, and GAPDH.</div></p></div><div class="aux"><div class="resc">Xiangling Chen, et al. J Biol Chem. 2012 Oct 5;287(41):34410-34418.</div><p class="links"><a class="dblinks" href="/pubmed/22908227" ref="ordinalpos=12&ncbi_uid=5371327&link_uid=22908227">Citation</a><a class="dblinks" href="/pmc/articles/PMC3464546/" ref="ordinalpos=12&ncbi_uid=5371327&link_uid=PMC3464546">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>13.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC2516253/figure/F1/" ref="ordinalpos=13&ncbi_uid=1483383&link_uid=PMC2516253" href="/pmc/articles/PMC2516253/"><img src="/pmc/articles/instance/2516253/bin/zpq9990843960001.gif" src-large="/pmc/articles/instance/2516253/bin/zpq9990843960001.jpg" alt="Fig. 1." /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC2516253/" ref="ordinalpos=13&ncbi_uid=1483383&link_uid=PMC2516253" image-link="/pmc/articles/PMC2516253/figure/F1/" class="imagepopup">Fig. 1. From: Extracellular loop C of NPC1L1 is important for binding to ezetimibe. </a></p><div class="supp"><p class="details"><div>[<sup>3</sup>H]AS binds directly to <span class="highlight" style="background-color:">dog</span> NPC1L1-K<sub>v</sub>1.1. (<i>A</i>) 2D model of <span class="highlight" style="background-color:">dog</span> NPC1L1-K<sub>v</sub>1.1. The membrane topology of <span class="highlight" style="background-color:">dog</span> NPC1L1 was predicted with HMMTOP and TMHMM servers available through http://expasy.org/tools/#ptm and manually refined. The pentahelical SSD is highlighted in purple. (<i>B</i> and <i>C</i>) <span class="highlight" style="background-color:">Dog</span> NPC1L1-K<sub>v</sub>1.1 is functional. <span class="highlight" style="background-color:">Dog</span> NPC1L1-K<sub>v</sub>1.1/MDCKII-Flp (<i>B</i>) or <span class="highlight" style="background-color:">dog</span> NPC1L1/MDCKII-Flp (<i>C</i>) cells were seeded on 96-well plates and incubated with increasing concentrations of [<sup>3</sup>H]AS for 4 h at 37°C. Specific binding was fit to a single-site saturation model yielding <i>K</i><sub>d</sub>/<i>B</i><sub>max</sub> values of 1.15 nM/3370 cpm for <span class="highlight" style="background-color:">Dog</span> NPC1L1-K<sub>v</sub>1.1/MDCKII-Flp cells (●) and 1.28 nM/6436 cpm for <span class="highlight" style="background-color:">dog</span> NPC1L1/MDCKII-Flp cells (▲). (<i>Inset</i>) [<sup>3</sup>H]cholesterol flux into <span class="highlight" style="background-color:">dog</span> NPC1L1-K<sub>v</sub>1.1/MDCKII-Flp cells (●) and <span class="highlight" style="background-color:">dog</span> NPC1L1/MDCKII-Flp cells (▲) was performed as described in the <i>Experimental Procedures</i> in the presence of increasing concentrations of PS. [<sup>3</sup>H]Ch flux was fit to a single-site inhibition model, yielding IC<sub>50</sub> values of 0.21 (<i>B</i>) and 0.24 nM (<i>C</i>) for <span class="highlight" style="background-color:">dog</span> NPC1L1-K<sub>v</sub>1.1/MDCKII-Flp cells (●) and <span class="highlight" style="background-color:">dog</span> NPC1L1/MDCKII-Flp cells (▲), respectively. (<i>D</i>) Strategy for affinity purification of <span class="highlight" style="background-color:">dog</span> NPC1L1-K<sub>v</sub>1.1. (<i>E</i> and <i>F</i>) Immunoprecipitation of <span class="highlight" style="background-color:">dog</span> NPC1L1-K<sub>v</sub>1.1 from membranes and cells. Membranes from <span class="highlight" style="background-color:">dog</span> NPC1L1-K<sub>v</sub>1.1/MDCKII-Flp (<i>E</i>) or <span class="highlight" style="background-color:">dog</span> NPC1L1/MDCKII-Flp (<i>F</i>) cells were incubated with 20 nM [<sup>3</sup>H]AS overnight and solubilized with 1% digitonin/0.03% sodium taurocholate for 30 min at 4°C, as described in <i>Experimental Procedures</i>. Solubilization of 35% or 26% of membrane bound [<sup>3</sup>H]AS activity from either <span class="highlight" style="background-color:">dog</span> NPC1L1-K<sub>v</sub>1.1 or <span class="highlight" style="background-color:">dog</span> NPC1L1 membranes, respectively, was obtained. Solubilized [<sup>3</sup>H]AS activity (S) was incubated with protein A Sepharose beads coated with an anti-K<sub>v</sub>1.1 antibody for 3 h at 4°C. Unbound [<sup>3</sup>H]AS activity (U) was collected, and the beads were washed three times before determination of [<sup>3</sup>H]AS bound (P). [<sup>3</sup>H]AS in U and P has been corrected to account for the dissociation of bound [<sup>3</sup>H]AS (<i>t</i><sub>1/2</sub> ≈6 h) during the time of immunoprecipitation. [<sup>3</sup>H]AS recovered in P of <span class="highlight" style="background-color:">dog</span> NPC1L1/MDCKII-Flp is identical to that obtained in the absence of anti-K<sub>v</sub>1.1 antibody. <span class="highlight" style="background-color:">Dog</span> NPC1L1-K<sub>v</sub>1.1/MDCKII-Flp (<i>E Inset</i>) or <span class="highlight" style="background-color:">dog</span> NPC1L1/MDCKII-Flp (<i>F Inset</i>) cells were incubated with 20 nM [<sup>3</sup>H]AS overnight. Free [<sup>3</sup>H]AS was removed from cells by aspiration as described in <i>Experimental Procedures</i>, and the [<sup>3</sup>H]AS activity bound to cells was solubilized with 1% digitonin/0.03% sodium taurocholate for 30 min at 4°C. The solubilized [<sup>3</sup>H]AS activity (S) was immunoprecipitated as indicated in <i>D</i>. Data in <i>E</i> and <i>F</i> are representative of 10 and 8 independent experiments from membranes and cells, respectively. (<i>G</i>) Characterization of affinity-purified <span class="highlight" style="background-color:">dog</span> NPC1L1-K<sub>v</sub>1.1. The solubilized (S), unbound (U), and purified (P) material of the immunoprecipitation from <span class="highlight" style="background-color:">dog</span> NPC1L1-K<sub>v</sub>1.1/MDCKII-Flp and <span class="highlight" style="background-color:">dog</span> NPC1L1/MDCKII-Flp membranes was resolved by SDS/PAGE, transferred onto a PVDF membrane, and analyzed with an anti-K<sub>v</sub>1.1 antibody. Two proteins of <i>M</i><sub>r</sub> 125 and 165 kDa are specifically recognized by the anti-K<sub>v</sub>1.1 antibody in the three NPC1L1-K<sub>v</sub>1.1 but not NPC1L1 samples. (<i>H</i>) Purified material (P) from <i>G</i> was resolved by SDS/PAGE and visualized by silver staining. Two bands at 125 and 165 kDa (indicated by red arrows) are present in the material purified from <span class="highlight" style="background-color:">dog</span> NPC1L1 K<sub>v</sub>1.1 but not <span class="highlight" style="background-color:">dog</span> NPC1L1. (<i>I</i>) Quantification histogram displaying the relative specificities scored by relative peptide queries (rPQ) of affinity-purified proteins identified by LC-MS/MS sequencing of the gel lanes in <i>H</i>. * indicates proteins for which MS/MS spectra are assigned from <span class="highlight" style="background-color:">dog</span> NPC1L1 K<sub>v</sub>1.1 but not <span class="highlight" style="background-color:">dog</span> NPC1L1-material. Values were 12 queries for NPC1L1 (gi 148223061) and 2 queries for Trx-related protein (gi 73963782).</div></p></div><div class="aux"><div class="resc">Adam B. Weinglass, et al. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11140-11145.</div><p class="links"><a class="dblinks" href="/pubmed/18682566" ref="ordinalpos=13&ncbi_uid=1483383&link_uid=18682566">Citation</a><a class="dblinks" href="/pmc/articles/PMC2516253/" ref="ordinalpos=13&ncbi_uid=1483383&link_uid=PMC2516253">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>14.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC7914568/figure/antibiotics-10-00171-f002/" ref="ordinalpos=14&ncbi_uid=19476047&link_uid=PMC7914568" href="/pmc/articles/PMC7914568/"><img src="/pmc/articles/instance/7914568/bin/antibiotics-10-00171-g002.gif" src-large="/pmc/articles/instance/7914568/bin/antibiotics-10-00171-g002.jpg" alt="Figure 2" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC7914568/" ref="ordinalpos=14&ncbi_uid=19476047&link_uid=PMC7914568" image-link="/pmc/articles/PMC7914568/figure/antibiotics-10-00171-f002/" class="imagepopup">Figure 2. From: Transmission Chains of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae at the Companion Animal Veterinary Clinic–Household Interface. </a></p><div class="supp"><p class="details"><div>Multi-locus sequence typing-distance based phylogenetic tree for extended-spectrum beta-lactamase-producing <i>Escherichia coli</i> isolates. D, <span class="highlight" style="background-color:">dog</span>; C, cat; CD, colonized <span class="highlight" style="background-color:">dog</span>; O, owner; lower case letter, environment; H1, household 1; H2, household 2; D68, <span class="highlight" style="background-color:">dog</span> 10; D5, <span class="highlight" style="background-color:">dog</span> 1; H1O1 t1 SK1, owner household 1; H1O1 t4, owner household 1; H1CD1 t1 SK2 <span class="highlight" style="background-color:">dog</span> household 1; D9, <span class="highlight" style="background-color:">dog</span> 1; D40, <span class="highlight" style="background-color:">dog</span> 5; D10, <span class="highlight" style="background-color:">dog</span> 2; D18, <span class="highlight" style="background-color:">dog</span> 1; C16 SK1, cat 2; D17, <span class="highlight" style="background-color:">dog</span> 2; H1CD1 t2, <span class="highlight" style="background-color:">dog</span> household 1; H1CD1 t1 SK1, <span class="highlight" style="background-color:">dog</span> household 1; H1f1, <span class="highlight" style="background-color:">dog</span>’s sleeping basket (living room); H1c1, water bowl; H1O1 t1 SK2, owner household 1; s7, <span class="highlight" style="background-color:">dog</span> cage; D69 SK2, <span class="highlight" style="background-color:">dog</span> 11; H1m1, carpet; h1y1, kitchen sponge; H1g1, <span class="highlight" style="background-color:">dog</span>’s blanket on terrace; D48, <span class="highlight" style="background-color:">dog</span> 7; H1O1 t2, owner household 1; H1h1, <span class="highlight" style="background-color:">dog</span>’s sleeping basket (bedroom); i11, small cabinet; H1CD1 t3, <span class="highlight" style="background-color:">dog</span> household 1; C17, cat 3; H1CD1 t4 SK2, <span class="highlight" style="background-color:">dog</span> household 1; D26, <span class="highlight" style="background-color:">dog</span> 3; C16 SK2, cat 2; H2O2 t2, owner household 2; H2O2 t1, owner household 2; D58 SK2, <span class="highlight" style="background-color:">dog</span> 9; D72, <span class="highlight" style="background-color:">dog</span> 12; *, whole genome sequencing conducted.</div></p></div><div class="aux"><div class="resc">Kira Schmitt, et al. Antibiotics (Basel). 2021 Feb;10(2):171.</div><p class="links"><a class="dblinks" href="/pubmed/33572066" ref="ordinalpos=14&ncbi_uid=19476047&link_uid=33572066">Citation</a><a class="dblinks" href="/pmc/articles/PMC7914568/" ref="ordinalpos=14&ncbi_uid=19476047&link_uid=PMC7914568">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>15.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC11098500/figure/ppat.1012204.g003/" ref="ordinalpos=15&ncbi_uid=31683434&link_uid=PMC11098500" href="/pmc/articles/PMC11098500/"><img src="/pmc/articles/instance/11098500/bin/ppat.1012204.g003.gif" src-large="/pmc/articles/instance/11098500/bin/ppat.1012204.g003.jpg" alt="Fig 3" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC11098500/" ref="ordinalpos=15&ncbi_uid=31683434&link_uid=PMC11098500" image-link="/pmc/articles/PMC11098500/figure/ppat.1012204.g003/" class="imagepopup">Fig 3. Crystal structure of chimeric SARS-CoV-2 RBD complexed with chimeric raccoon <span class="highlight" style="background-color:">dog</span> ACE2.. From: Structural basis for raccoon <span class="highlight" style="background-color:">dog</span> receptor recognition by SARS-CoV-2. </a></p><div class="supp"><p class="details"><div>(<b>A</b>) Overall structure of the complex. The chimeric RBD contains the core structure (in cyan) from SARS-CoV-1 RBD and receptor-binding motif (RBM) (in magenta) from SARS-CoV-2 RBD. The chimeric raccoon <span class="highlight" style="background-color:">dog</span> ACE2 contains the core structure (in green) from human ACE2 and three virus-binding motifs (VBMs) (in orange) from raccoon <span class="highlight" style="background-color:">dog</span> ACE2. (<b>B</b>) Structural interface between SARS-CoV-2 RBM and raccoon <span class="highlight" style="background-color:">dog</span> VBMs. Three virus-binding hotspots are highlighted. The key residues that differ between human ACE2 and raccoon <span class="highlight" style="background-color:">dog</span> ACE2 are shown in sticks.</div></p></div><div class="aux"><div class="resc">Fu-Chun Hsueh, et al. PLoS Pathog. 2024 May;20(5):e1012204.</div><p class="links"><a class="dblinks" href="/pubmed/38709834" ref="ordinalpos=15&ncbi_uid=31683434&link_uid=38709834">Citation</a><a class="dblinks" href="/pmc/articles/PMC11098500/" ref="ordinalpos=15&ncbi_uid=31683434&link_uid=PMC11098500">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>16.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC7333044/figure/fig2/" ref="ordinalpos=16&ncbi_uid=17617727&link_uid=PMC7333044" href="/pmc/articles/PMC7333044/"><img src="/pmc/articles/instance/7333044/bin/BMRI2020-2615787.002.gif" src-large="/pmc/articles/instance/7333044/bin/BMRI2020-2615787.002.jpg" alt="Figure 2" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC7333044/" ref="ordinalpos=16&ncbi_uid=17617727&link_uid=PMC7333044" image-link="/pmc/articles/PMC7333044/figure/fig2/" class="imagepopup">Figure 2. From: Detection of Metalloproteases and Cysteine Proteases RNA Transcripts of Leishmania (Leishmania) infantum in Ear Edge Skin of Naturally Infected Dogs. </a></p><div class="supp"><p class="details"><div>Expression of metalloprotease and cysteine protease genes from <i>Leishmania</i> (<i>L.</i>) <i>infantum</i> in naturally infected dogs. Total RNA from <span class="highlight" style="background-color:">dog</span>'s ear edge skin was extracted and reverse transcription polymerase chain reactions (RT-PCR) were performed using specific primers for the <i>β</i>-actin (a), metalloprotease (b), and cysteine protease (c) genes. RT-PCR products were resolved on a 2% agarose gels stained with Nancy-520. A 100 bp DNA ladder (L) was used as a molecular weight marked and revealed single 87 bp, 202 bp, and 227 bp fragments, respectively, in the tested cDNA samples. Asymptomatic (<span class="highlight" style="background-color:">Dog</span> 2, <span class="highlight" style="background-color:">Dog</span> 4, Dog6, <span class="highlight" style="background-color:">Dog</span> 11, <span class="highlight" style="background-color:">Dog</span> 12, <span class="highlight" style="background-color:">Dog</span> 16, and <span class="highlight" style="background-color:">Dog</span> 19), oligosymptomatic (<span class="highlight" style="background-color:">Dog</span> 3, <span class="highlight" style="background-color:">Dog</span> 5, <span class="highlight" style="background-color:">Dog</span> 7, <span class="highlight" style="background-color:">Dog</span> 8, <span class="highlight" style="background-color:">Dog</span> 9, <span class="highlight" style="background-color:">Dog</span> 10, <span class="highlight" style="background-color:">Dog</span> 13, <span class="highlight" style="background-color:">Dog</span> 14, and <span class="highlight" style="background-color:">Dog</span> 20) and polysymptomatic (<span class="highlight" style="background-color:">Dog</span> 1, <span class="highlight" style="background-color:">Dog</span> 15, <span class="highlight" style="background-color:">Dog</span> 17 and <span class="highlight" style="background-color:">Dog</span> 21).</div></p></div><div class="aux"><div class="resc">Laura Barral Veloso, et al. Biomed Res Int. 2020;2020:2615787.</div><p class="links"><a class="dblinks" href="/pubmed/32685457" ref="ordinalpos=16&ncbi_uid=17617727&link_uid=32685457">Citation</a><a class="dblinks" href="/pmc/articles/PMC7333044/" ref="ordinalpos=16&ncbi_uid=17617727&link_uid=PMC7333044">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>17.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC5988334/figure/pntd.0006490.g001/" ref="ordinalpos=17&ncbi_uid=12619599&link_uid=PMC5988334" href="/pmc/articles/PMC5988334/"><img src="/pmc/articles/instance/5988334/bin/pntd.0006490.g001.gif" src-large="/pmc/articles/instance/5988334/bin/pntd.0006490.g001.jpg" alt="Fig 1" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC5988334/" ref="ordinalpos=17&ncbi_uid=12619599&link_uid=PMC5988334" image-link="/pmc/articles/PMC5988334/figure/pntd.0006490.g001/" class="imagepopup">Fig 1. From: Cost-effectiveness of <span class="highlight" style="background-color:">dog</span> rabies vaccination programs in East Africa. </a></p><div class="supp"><p class="details"><div>Cases of <span class="highlight" style="background-color:">dog</span> rabies for alternative <span class="highlight" style="background-color:">dog</span> rabies vaccination programs in East Africa: A. Low levels of transmission; B. High levels of transmission<sup>a</sup> Footnotes: a. Results for two scenarios for <span class="highlight" style="background-color:">dog</span> rabies vaccination programs in an East African population of 1 million persons (approximately 2/3 urban, 1/3 rural), with approximately 82,000 dogs (). Vaccination programs: Option 1, annual mass <span class="highlight" style="background-color:">dog</span> vaccination, resulting in 50% of the <span class="highlight" style="background-color:">dog</span> population vaccinated, and Option 2, biannual (twice per year) mass <span class="highlight" style="background-color:">dog</span> vaccination, resulting in 20% of the <span class="highlight" style="background-color:">dog</span> population vaccinated for each vaccination program. Rabies transmission risk is defined, in part, by the number of bites per rabid <span class="highlight" style="background-color:">dog</span> to another <span class="highlight" style="background-color:">dog</span> (see ).</div></p></div><div class="aux"><div class="resc">Rebekah H. Borse, et al. PLoS Negl Trop Dis. 2018 May;12(5):e0006490.</div><p class="links"><a class="dblinks" href="/pubmed/29791440" ref="ordinalpos=17&ncbi_uid=12619599&link_uid=29791440">Citation</a><a class="dblinks" href="/pmc/articles/PMC5988334/" ref="ordinalpos=17&ncbi_uid=12619599&link_uid=PMC5988334">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>18.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC5725459/figure/Fig1/" ref="ordinalpos=18&ncbi_uid=11727850&link_uid=PMC5725459" href="/pmc/articles/PMC5725459/"><img src="/pmc/articles/instance/5725459/bin/41598_2017_17817_Fig1_HTML.gif" src-large="/pmc/articles/instance/5725459/bin/41598_2017_17817_Fig1_HTML.jpg" alt="Figure 1" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC5725459/" ref="ordinalpos=18&ncbi_uid=11727850&link_uid=PMC5725459" image-link="/pmc/articles/PMC5725459/figure/Fig1/" class="imagepopup">Figure 1. From: Functional and evolutionary analysis of Korean bob-tailed native <span class="highlight" style="background-color:">dog</span> using whole-genome sequencing data. </a></p><div class="supp"><p class="details"><div>Examples of Donggyeong <span class="highlight" style="background-color:">dog</span>-specific non-synonymous SNPs and consequential amino acid variants. Top panel shows gene structure with the direction of transcription (blue arrow). Bottom panel indicates positions of non-synonymous SNPs and comparison of amino acids among different <span class="highlight" style="background-color:">dog</span> breeds and related species. Two different amino acids corresponding to two nucleotide variants in Donggyeong <span class="highlight" style="background-color:">dog</span> are shown together with a slash delimiter. The dash symbol represents a gap in multiple sequene alignment. DG: Donggyeong <span class="highlight" style="background-color:">dog</span>, DQ: Diquing village <span class="highlight" style="background-color:">dog</span>, KM: Kunming <span class="highlight" style="background-color:">dog</span>, YJ: Yingjiang village <span class="highlight" style="background-color:">dog</span>, GS: German shepherd, LJ: Lijiang village <span class="highlight" style="background-color:">dog</span>, TM: Tibetan mastiff. Other <span class="highlight" style="background-color:">dog</span> breeds not shown here contained the same variant as <span class="highlight" style="background-color:">dog</span> breeds with blue color shown in this figure.</div></p></div><div class="aux"><div class="resc">Daehwan Lee, et al. Sci Rep. 2017;7:17303.</div><p class="links"><a class="dblinks" href="/pubmed/29230066" ref="ordinalpos=18&ncbi_uid=11727850&link_uid=29230066">Citation</a><a class="dblinks" href="/pmc/articles/PMC5725459/" ref="ordinalpos=18&ncbi_uid=11727850&link_uid=PMC5725459">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>19.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC10484941/figure/Fig1/" ref="ordinalpos=19&ncbi_uid=29229562&link_uid=PMC10484941" href="/pmc/articles/PMC10484941/"><img src="/pmc/articles/instance/10484941/bin/41598_2023_41849_Fig1_HTML.gif" src-large="/pmc/articles/instance/10484941/bin/41598_2023_41849_Fig1_HTML.jpg" alt="Figure 1" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC10484941/" ref="ordinalpos=19&ncbi_uid=29229562&link_uid=PMC10484941" image-link="/pmc/articles/PMC10484941/figure/Fig1/" class="imagepopup">Figure 1. From: Modulation of <span class="highlight" style="background-color:">dog</span>–owner relationship and <span class="highlight" style="background-color:">dog</span> social and cognitive behavior by owner temperament and <span class="highlight" style="background-color:">dog</span> breed group. </a></p><div class="supp"><p class="details"><div>Main research questions (RQ1–RQ5). We examined the triadic connection between the <span class="highlight" style="background-color:">dog</span> owner temperament, <span class="highlight" style="background-color:">dog</span>–owner relationship, and the <span class="highlight" style="background-color:">dog</span> social and cognitive behavior (RQ1–3). Also <span class="highlight" style="background-color:">dog</span> physical activity connection with <span class="highlight" style="background-color:">dog</span>–owner relationship and <span class="highlight" style="background-color:">dog</span> behavior was examined (RQ4), and the modulation of the connection between the owner temperament and <span class="highlight" style="background-color:">dog</span> behavior by the <span class="highlight" style="background-color:">dog</span> breed group (herding dogs vs. primitive type breeds, RQ5).</div></p></div><div class="aux"><div class="resc">Miiamaaria V. Kujala, et al. Sci Rep. 2023;13:14739.</div><p class="links"><a class="dblinks" href="/pubmed/37679427" ref="ordinalpos=19&ncbi_uid=29229562&link_uid=37679427">Citation</a><a class="dblinks" href="/pmc/articles/PMC10484941/" ref="ordinalpos=19&ncbi_uid=29229562&link_uid=PMC10484941">Full text</a></p></div></div><div class="clear"></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><span>20.</span></div><div class="rslt"><a class="rprt_img figpopup imagepopup" image-link="/pmc/articles/PMC4855366/figure/Fig6/" ref="ordinalpos=20&ncbi_uid=9037146&link_uid=PMC4855366" href="/pmc/articles/PMC4855366/"><img src="/pmc/articles/instance/4855366/bin/13071_2016_1518_Fig6_HTML.gif" src-large="/pmc/articles/instance/4855366/bin/13071_2016_1518_Fig6_HTML.jpg" alt="Fig. 6" /></a><div class="rprt_cont"><p class="title"><a href="/pmc/articles/PMC4855366/" ref="ordinalpos=20&ncbi_uid=9037146&link_uid=PMC4855366" image-link="/pmc/articles/PMC4855366/figure/Fig6/" class="imagepopup">Fig. 6. From: Molecular identification and antigenic characterization of a merozoite surface antigen and a secreted antigen of Babesia canis (BcMSA1 and BcSA1). </a></p><div class="supp"><p class="details"><div>Evaluation of ICT based on rBcMSA1 and rBcSA1. <b>a</b> Cross-reactivity of ICT using rBcMSA1 with closely related parasite-infected canine sera: lane 1, <i>B. rossi</i>-infected <span class="highlight" style="background-color:">dog</span> serum; lane 2, <i>B. vogeli</i>-infected <span class="highlight" style="background-color:">dog</span> serum; lane 3, <i>B. gibsoni</i>-infected <span class="highlight" style="background-color:">dog</span> serum; lane 4, <i>L. infantum</i>-infected <span class="highlight" style="background-color:">dog</span> serum; lane 5, <i>B. canis-</i>infected <span class="highlight" style="background-color:">dog</span> serum; lane 6, a SPF <span class="highlight" style="background-color:">dog</span> serum; <b>b</b> Specific antibody responses to rBcMSA1 in sequential serum samples from a non-splenectomized <span class="highlight" style="background-color:">dog</span> experimentally infected with <i>B. canis</i>; <b>c</b> Cross-reactivity of rBcSA1 with closely related parasite-infected canine sera: lane 1, SPF <span class="highlight" style="background-color:">dog</span> serum; lane 2, <i>B. canis</i>-infected <span class="highlight" style="background-color:">dog</span> serum; lane 3, <i>B. rossi</i>-infected <span class="highlight" style="background-color:">dog</span> serum; lane 4, <i>B. vogeli</i>-infected <span class="highlight" style="background-color:">dog</span> serum; lane 5, <i>B. gibsoni</i>-infected <span class="highlight" style="background-color:">dog</span> serum; lane 6, <i>L. infantum</i>-infected <span class="highlight" style="background-color:">dog</span> serum; <b>d</b> Specific antibody responses to rBcSA1 in sequential serum samples from a non-splenectomized <span class="highlight" style="background-color:">dog</span> experimentally infected with <i>B. canis</i> </div></p></div><div class="aux"><div class="resc">Mo Zhou, et al. Parasit Vectors. 2016;9:257.</div><p class="links"><a class="dblinks" href="/pubmed/27141812" ref="ordinalpos=20&ncbi_uid=9037146&link_uid=27141812">Citation</a><a class="dblinks" href="/pmc/articles/PMC4855366/" ref="ordinalpos=20&ncbi_uid=9037146&link_uid=PMC4855366">Full text</a></p></div></div><div class="clear"></div></div></div></div>
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|
||
<li>
|
||
<a class="text-white" href="//www.nlm.nih.gov/">NLM</a>
|
||
</li>
|
||
<li>
|
||
<a class="text-white" href="https://www.nih.gov/">NIH</a>
|
||
</li>
|
||
<li>
|
||
<a class="text-white" href="https://www.hhs.gov/">HHS</a>
|
||
</li>
|
||
<li>
|
||
<a class="text-white" href="https://www.usa.gov/">USA.gov</a>
|
||
</li>
|
||
</ul>
|
||
</nav>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</section>
|
||
<script type="text/javascript" src="/portal/portal3rc.fcgi/rlib/js/InstrumentOmnitureBaseJS/InstrumentNCBIConfigJS/InstrumentNCBIBaseJS/InstrumentPageStarterJS.js?v=1"> </script>
|
||
<script type="text/javascript" src="/portal/portal3rc.fcgi/static/js/hfjs2.js"> </script>
|
||
</div>
|
||
|
||
</div>
|
||
<div><input name="EntrezSystem2.PEntrez.DbConnector.Db" sid="1" type="hidden" value="pmc" /><input name="EntrezSystem2.PEntrez.DbConnector.LastDb" sid="1" type="hidden" value="pmc" /><input name="EntrezSystem2.PEntrez.DbConnector.Term" sid="1" type="hidden" value="dog" /><input name="EntrezSystem2.PEntrez.DbConnector.LastTabCmd" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.DbConnector.LastQueryKey" sid="1" type="hidden" value="6028" /><input name="EntrezSystem2.PEntrez.DbConnector.IdsFromResult" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.DbConnector.LastIdsFromResult" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.DbConnector.LinkName" sid="1" type="hidden" /><input name="EntrezSystem2.PEntrez.DbConnector.LinkReadableName" sid="1" type="hidden" /><input name="EntrezSystem2.PEntrez.DbConnector.LinkSrcDb" sid="1" type="hidden" /><input name="EntrezSystem2.PEntrez.DbConnector.Cmd" sid="1" type="hidden" /><input name="EntrezSystem2.PEntrez.DbConnector.TabCmd" sid="1" type="hidden" /><input name="EntrezSystem2.PEntrez.DbConnector.QueryKey" sid="1" type="hidden" /></div>
|
||
<input type="hidden" name="p$a" id="p$a" /><input type="hidden" name="p$l" id="p$l" value="EntrezSystem2" /><input type="hidden" name="p$st" id="p$st" value="pmc" /><input name="SessionId" id="SessionId" value="CE8B5AF87C7FFCB1_0191SID" disabled="disabled" type="hidden" /><input name="Snapshot" id="Snapshot" value="/projects/PMC/PMCEntrez@3.28" disabled="disabled" type="hidden" /></form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<!-- CE8B5AF87C7FFCB1_0191SID /projects/PMC/PMCEntrez@3.28 portal106 v4.1.r689238 Tue, Oct 22 2024 16:10:51 -->
|
||
<span id="portal-csrf-token" style="display:none" data-token="CE8B5AF87C7FFCB1_0191SID"></span>
|
||
|
||
|
||
<script type='text/javascript' src='/portal/js/portal.js'></script><script type="text/javascript" src="//static.pubmed.gov/portal/portal3rc.fcgi/4213537/js/4200673/3812534/4087685/3812535/3781606/4120364/4191189/4080513/4181896/4186313/4191192/3758627/2146917/1053413/3812291/3908752/3423/2099570/4076482/3397055/4001808.js" snapshot="pmc"></script></body>
|
||
</html> |