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<meta name="keywords" content="CN378607, childhood malignant glioma, disease or syndrome, pediatric high-grade glioma, phgg, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A malignant high-grade glioma that occurs during childhood in the central nervous system." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=1053981
|
||
ConceptID=CN378607
|
||
-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Pediatric high-grade glioma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1053981</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier assigned by MedGen (starting with CN) for terms that cannot be identified in NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">CN378607</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>childhood malignant glioma; pediatric high-grade glioma; pHGG</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:1010030" target="_blank">MONDO:1010030</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A malignant high-grade glioma that occurs during childhood in the central nervous system. [from <a title="Monarch Initiative" href="https://monarchinitiative.org/" class="defSource" target="_blank">MONDO</a>]</div>
|
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</div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38849845">Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zuckermann M,
|
||
He C,
|
||
Andrews J,
|
||
Bagchi A,
|
||
Sloan-Henry R,
|
||
Bianski B,
|
||
Xie J,
|
||
Wang Y,
|
||
Twarog N,
|
||
Onar-Thomas A,
|
||
Ernst KJ,
|
||
Yang L,
|
||
Li Y,
|
||
Zhu X,
|
||
Ocasio JK,
|
||
Budd KM,
|
||
Dalton J,
|
||
Li X,
|
||
Chepyala D,
|
||
Zhang J,
|
||
Xu K,
|
||
Hover L,
|
||
Roach JT,
|
||
Chan KC,
|
||
Hofmann N,
|
||
McKinnon PJ,
|
||
Pfister SM,
|
||
Shelat AA,
|
||
Rankovic Z,
|
||
Freeman BB 3rd,
|
||
Chiang J,
|
||
Jones DTW,
|
||
Tinkle CL,
|
||
Baker SJ</span><br />
|
||
<span class="medgenPMjournal">Mol Cancer</span>
|
||
2024 Jun 7;23(1):123.
|
||
doi: 10.1186/s12943-024-02027-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38849845" target="_blank">38849845</a><a href="/pmc/articles/PMC11157767" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35397478">Upfront molecular targeted therapy for the treatment of BRAF-mutant pediatric high-grade glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rosenberg T,
|
||
Yeo KK,
|
||
Mauguen A,
|
||
Alexandrescu S,
|
||
Prabhu SP,
|
||
Tsai JW,
|
||
Malinowski S,
|
||
Joshirao M,
|
||
Parikh K,
|
||
Farouk Sait S,
|
||
Rosenblum MK,
|
||
Benhamida JK,
|
||
Michaiel G,
|
||
Tran HN,
|
||
Dahiya S,
|
||
Kachurak K,
|
||
Friedman GK,
|
||
Krystal JI,
|
||
Huang MA,
|
||
Margol AS,
|
||
Wright KD,
|
||
Aguilera D,
|
||
MacDonald TJ,
|
||
Chi SN,
|
||
Karajannis MA</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2022 Nov 2;24(11):1964-1975.
|
||
doi: 10.1093/neuonc/noac096.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35397478" target="_blank">35397478</a><a href="/pmc/articles/PMC9629451" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26448930">Molecular Biology in Pediatric High-Grade Glioma: Impact on Prognosis and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rizzo D,
|
||
Ruggiero A,
|
||
Martini M,
|
||
Rizzo V,
|
||
Maurizi P,
|
||
Riccardi R</span><br />
|
||
<span class="medgenPMjournal">Biomed Res Int</span>
|
||
2015;2015:215135.
|
||
Epub 2015 Sep 13
|
||
doi: 10.1155/2015/215135.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26448930" target="_blank">26448930</a><a href="/pmc/articles/PMC4584033" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22pediatric%20high-grade%20glioma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (9)</a></div></div>
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||
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|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38423245">Clinicopathological and molecular landscape of 5-year IDH-wild-type glioblastoma survivors: A multicentric retrospective study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Miele E,
|
||
Anghileri E,
|
||
Calatozzolo C,
|
||
Lazzarini E,
|
||
Patrizi S,
|
||
Ciolfi A,
|
||
Pedace L,
|
||
Patanè M,
|
||
Abballe L,
|
||
Paterra R,
|
||
Maddaloni L,
|
||
Barresi S,
|
||
Mastronuzzi A,
|
||
Petruzzi A,
|
||
Tramacere I,
|
||
Farinotti M,
|
||
Gurrieri L,
|
||
Pirola E,
|
||
Scarpelli M,
|
||
Lombardi G,
|
||
Villani V,
|
||
Simonelli M,
|
||
Merli R,
|
||
Salmaggi A,
|
||
Tartaglia M,
|
||
Silvani A,
|
||
DiMeco F,
|
||
Calistri D,
|
||
Lamperti E,
|
||
Locatelli F,
|
||
Indraccolo S,
|
||
Pollo B</span><br />
|
||
<span class="medgenPMjournal">Cancer Lett</span>
|
||
2024 Apr 28;588:216711.
|
||
Epub 2024 Feb 27
|
||
doi: 10.1016/j.canlet.2024.216711.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38423245" target="_blank">38423245</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32504402">Pediatric high-grade glioma: aberrant epigenetics and kinase signaling define emerging therapeutic opportunities.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sun Y,
|
||
Bailey CP,
|
||
Sadighi Z,
|
||
Zaky W,
|
||
Chandra J</span><br />
|
||
<span class="medgenPMjournal">J Neurooncol</span>
|
||
2020 Oct;150(1):17-26.
|
||
Epub 2020 Jun 5
|
||
doi: 10.1007/s11060-020-03546-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32504402" target="_blank">32504402</a><a href="/pmc/articles/PMC10141680" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27282398">Pediatric high-grade glioma: biologically and clinically in need of new thinking.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jones C,
|
||
Karajannis MA,
|
||
Jones DTW,
|
||
Kieran MW,
|
||
Monje M,
|
||
Baker SJ,
|
||
Becher OJ,
|
||
Cho YJ,
|
||
Gupta N,
|
||
Hawkins C,
|
||
Hargrave D,
|
||
Haas-Kogan DA,
|
||
Jabado N,
|
||
Li XN,
|
||
Mueller S,
|
||
Nicolaides T,
|
||
Packer RJ,
|
||
Persson AI,
|
||
Phillips JJ,
|
||
Simonds EF,
|
||
Stafford JM,
|
||
Tang Y,
|
||
Pfister SM,
|
||
Weiss WA</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2017 Feb 1;19(2):153-161.
|
||
doi: 10.1093/neuonc/now101.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27282398" target="_blank">27282398</a><a href="/pmc/articles/PMC5464243" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27006176">Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jakacki RI,
|
||
Cohen KJ,
|
||
Buxton A,
|
||
Krailo MD,
|
||
Burger PC,
|
||
Rosenblum MK,
|
||
Brat DJ,
|
||
Hamilton RL,
|
||
Eckel SP,
|
||
Zhou T,
|
||
Lavey RS,
|
||
Pollack IF</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2016 Oct;18(10):1442-50.
|
||
Epub 2016 Mar 22
|
||
doi: 10.1093/neuonc/now038.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27006176" target="_blank">27006176</a><a href="/pmc/articles/PMC5035517" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24705251">The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wu G,
|
||
Diaz AK,
|
||
Paugh BS,
|
||
Rankin SL,
|
||
Ju B,
|
||
Li Y,
|
||
Zhu X,
|
||
Qu C,
|
||
Chen X,
|
||
Zhang J,
|
||
Easton J,
|
||
Edmonson M,
|
||
Ma X,
|
||
Lu C,
|
||
Nagahawatte P,
|
||
Hedlund E,
|
||
Rusch M,
|
||
Pounds S,
|
||
Lin T,
|
||
Onar-Thomas A,
|
||
Huether R,
|
||
Kriwacki R,
|
||
Parker M,
|
||
Gupta P,
|
||
Becksfort J,
|
||
Wei L,
|
||
Mulder HL,
|
||
Boggs K,
|
||
Vadodaria B,
|
||
Yergeau D,
|
||
Russell JC,
|
||
Ochoa K,
|
||
Fulton RS,
|
||
Fulton LL,
|
||
Jones C,
|
||
Boop FA,
|
||
Broniscer A,
|
||
Wetmore C,
|
||
Gajjar A,
|
||
Ding L,
|
||
Mardis ER,
|
||
Wilson RK,
|
||
Taylor MR,
|
||
Downing JR,
|
||
Ellison DW,
|
||
Zhang J,
|
||
Baker SJ</span><br />
|
||
<span class="medgenPMjournal">Nat Genet</span>
|
||
2014 May;46(5):444-450.
|
||
Epub 2014 Apr 6
|
||
doi: 10.1038/ng.2938.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24705251" target="_blank">24705251</a><a href="/pmc/articles/PMC4056452" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pediatric%20high-grade%20glioma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (44)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38423245">Clinicopathological and molecular landscape of 5-year IDH-wild-type glioblastoma survivors: A multicentric retrospective study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Miele E,
|
||
Anghileri E,
|
||
Calatozzolo C,
|
||
Lazzarini E,
|
||
Patrizi S,
|
||
Ciolfi A,
|
||
Pedace L,
|
||
Patanè M,
|
||
Abballe L,
|
||
Paterra R,
|
||
Maddaloni L,
|
||
Barresi S,
|
||
Mastronuzzi A,
|
||
Petruzzi A,
|
||
Tramacere I,
|
||
Farinotti M,
|
||
Gurrieri L,
|
||
Pirola E,
|
||
Scarpelli M,
|
||
Lombardi G,
|
||
Villani V,
|
||
Simonelli M,
|
||
Merli R,
|
||
Salmaggi A,
|
||
Tartaglia M,
|
||
Silvani A,
|
||
DiMeco F,
|
||
Calistri D,
|
||
Lamperti E,
|
||
Locatelli F,
|
||
Indraccolo S,
|
||
Pollo B</span><br />
|
||
<span class="medgenPMjournal">Cancer Lett</span>
|
||
2024 Apr 28;588:216711.
|
||
Epub 2024 Feb 27
|
||
doi: 10.1016/j.canlet.2024.216711.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38423245" target="_blank">38423245</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33838625">Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Friedman GK,
|
||
Johnston JM,
|
||
Bag AK,
|
||
Bernstock JD,
|
||
Li R,
|
||
Aban I,
|
||
Kachurak K,
|
||
Nan L,
|
||
Kang KD,
|
||
Totsch S,
|
||
Schlappi C,
|
||
Martin AM,
|
||
Pastakia D,
|
||
McNall-Knapp R,
|
||
Farouk Sait S,
|
||
Khakoo Y,
|
||
Karajannis MA,
|
||
Woodling K,
|
||
Palmer JD,
|
||
Osorio DS,
|
||
Leonard J,
|
||
Abdelbaki MS,
|
||
Madan-Swain A,
|
||
Atkinson TP,
|
||
Whitley RJ,
|
||
Fiveash JB,
|
||
Markert JM,
|
||
Gillespie GY</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2021 Apr 29;384(17):1613-1622.
|
||
Epub 2021 Apr 10
|
||
doi: 10.1056/NEJMoa2024947.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33838625" target="_blank">33838625</a><a href="/pmc/articles/PMC8284840" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28357536">Pediatric high-grade glioma: current molecular landscape and therapeutic approaches.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Braunstein S,
|
||
Raleigh D,
|
||
Bindra R,
|
||
Mueller S,
|
||
Haas-Kogan D</span><br />
|
||
<span class="medgenPMjournal">J Neurooncol</span>
|
||
2017 Sep;134(3):541-549.
|
||
Epub 2017 Mar 29
|
||
doi: 10.1007/s11060-017-2393-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28357536" target="_blank">28357536</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27006176">Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jakacki RI,
|
||
Cohen KJ,
|
||
Buxton A,
|
||
Krailo MD,
|
||
Burger PC,
|
||
Rosenblum MK,
|
||
Brat DJ,
|
||
Hamilton RL,
|
||
Eckel SP,
|
||
Zhou T,
|
||
Lavey RS,
|
||
Pollack IF</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2016 Oct;18(10):1442-50.
|
||
Epub 2016 Mar 22
|
||
doi: 10.1093/neuonc/now038.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27006176" target="_blank">27006176</a><a href="/pmc/articles/PMC5035517" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24705251">The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wu G,
|
||
Diaz AK,
|
||
Paugh BS,
|
||
Rankin SL,
|
||
Ju B,
|
||
Li Y,
|
||
Zhu X,
|
||
Qu C,
|
||
Chen X,
|
||
Zhang J,
|
||
Easton J,
|
||
Edmonson M,
|
||
Ma X,
|
||
Lu C,
|
||
Nagahawatte P,
|
||
Hedlund E,
|
||
Rusch M,
|
||
Pounds S,
|
||
Lin T,
|
||
Onar-Thomas A,
|
||
Huether R,
|
||
Kriwacki R,
|
||
Parker M,
|
||
Gupta P,
|
||
Becksfort J,
|
||
Wei L,
|
||
Mulder HL,
|
||
Boggs K,
|
||
Vadodaria B,
|
||
Yergeau D,
|
||
Russell JC,
|
||
Ochoa K,
|
||
Fulton RS,
|
||
Fulton LL,
|
||
Jones C,
|
||
Boop FA,
|
||
Broniscer A,
|
||
Wetmore C,
|
||
Gajjar A,
|
||
Ding L,
|
||
Mardis ER,
|
||
Wilson RK,
|
||
Taylor MR,
|
||
Downing JR,
|
||
Ellison DW,
|
||
Zhang J,
|
||
Baker SJ</span><br />
|
||
<span class="medgenPMjournal">Nat Genet</span>
|
||
2014 May;46(5):444-450.
|
||
Epub 2014 Apr 6
|
||
doi: 10.1038/ng.2938.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24705251" target="_blank">24705251</a><a href="/pmc/articles/PMC4056452" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pediatric%20high-grade%20glioma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (57)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37643378">Phase II Trial of Dabrafenib Plus Trametinib in Relapsed/Refractory BRAF V600-Mutant Pediatric High-Grade Glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hargrave DR,
|
||
Terashima K,
|
||
Hara J,
|
||
Kordes UR,
|
||
Upadhyaya SA,
|
||
Sahm F,
|
||
Bouffet E,
|
||
Packer RJ,
|
||
Witt O,
|
||
Sandalic L,
|
||
Kieloch A,
|
||
Russo M,
|
||
Cohen KJ;
|
||
Investigators involved in the high-grade glioma cohort</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2023 Nov 20;41(33):5174-5183.
|
||
Epub 2023 Aug 29
|
||
doi: 10.1200/JCO.23.00558.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37643378" target="_blank">37643378</a><a href="/pmc/articles/PMC10666989" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36125896">H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Haase S,
|
||
Banerjee K,
|
||
Mujeeb AA,
|
||
Hartlage CS,
|
||
Núñez FM,
|
||
Núñez FJ,
|
||
Alghamri MS,
|
||
Kadiyala P,
|
||
Carney S,
|
||
Barissi MN,
|
||
Taher AW,
|
||
Brumley EK,
|
||
Thompson S,
|
||
Dreyer JT,
|
||
Alindogan CT,
|
||
Garcia-Fabiani MB,
|
||
Comba A,
|
||
Venneti S,
|
||
Ravikumar V,
|
||
Koschmann C,
|
||
Carcaboso ÁM,
|
||
Vinci M,
|
||
Rao A,
|
||
Yu JS,
|
||
Lowenstein PR,
|
||
Castro MG</span><br />
|
||
<span class="medgenPMjournal">J Clin Invest</span>
|
||
2022 Nov 15;132(22)
|
||
doi: 10.1172/JCI154229.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36125896" target="_blank">36125896</a><a href="/pmc/articles/PMC9663161" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35191733">Nimotuzumab as Additional Therapy for GLIOMA in Pediatric and Adolescent: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Parenrengi MA,
|
||
Suryaningtyas W,
|
||
Al Fauzi A,
|
||
Hafid Bajamal A,
|
||
Kusumastuti K,
|
||
Utomo B,
|
||
Muslim Hidayat Thamrin A,
|
||
Sulistiono B</span><br />
|
||
<span class="medgenPMjournal">Cancer Control</span>
|
||
2022 Jan-Dec;29:10732748211053927.
|
||
doi: 10.1177/10732748211053927.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35191733" target="_blank">35191733</a><a href="/pmc/articles/PMC8874160" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32504402">Pediatric high-grade glioma: aberrant epigenetics and kinase signaling define emerging therapeutic opportunities.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sun Y,
|
||
Bailey CP,
|
||
Sadighi Z,
|
||
Zaky W,
|
||
Chandra J</span><br />
|
||
<span class="medgenPMjournal">J Neurooncol</span>
|
||
2020 Oct;150(1):17-26.
|
||
Epub 2020 Jun 5
|
||
doi: 10.1007/s11060-020-03546-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32504402" target="_blank">32504402</a><a href="/pmc/articles/PMC10141680" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27006176">Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jakacki RI,
|
||
Cohen KJ,
|
||
Buxton A,
|
||
Krailo MD,
|
||
Burger PC,
|
||
Rosenblum MK,
|
||
Brat DJ,
|
||
Hamilton RL,
|
||
Eckel SP,
|
||
Zhou T,
|
||
Lavey RS,
|
||
Pollack IF</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2016 Oct;18(10):1442-50.
|
||
Epub 2016 Mar 22
|
||
doi: 10.1093/neuonc/now038.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27006176" target="_blank">27006176</a><a href="/pmc/articles/PMC5035517" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pediatric%20high-grade%20glioma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (44)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38423245">Clinicopathological and molecular landscape of 5-year IDH-wild-type glioblastoma survivors: A multicentric retrospective study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Miele E,
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Anghileri E,
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Calatozzolo C,
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Lazzarini E,
|
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Patrizi S,
|
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Ciolfi A,
|
||
Pedace L,
|
||
Patanè M,
|
||
Abballe L,
|
||
Paterra R,
|
||
Maddaloni L,
|
||
Barresi S,
|
||
Mastronuzzi A,
|
||
Petruzzi A,
|
||
Tramacere I,
|
||
Farinotti M,
|
||
Gurrieri L,
|
||
Pirola E,
|
||
Scarpelli M,
|
||
Lombardi G,
|
||
Villani V,
|
||
Simonelli M,
|
||
Merli R,
|
||
Salmaggi A,
|
||
Tartaglia M,
|
||
Silvani A,
|
||
DiMeco F,
|
||
Calistri D,
|
||
Lamperti E,
|
||
Locatelli F,
|
||
Indraccolo S,
|
||
Pollo B</span><br />
|
||
<span class="medgenPMjournal">Cancer Lett</span>
|
||
2024 Apr 28;588:216711.
|
||
Epub 2024 Feb 27
|
||
doi: 10.1016/j.canlet.2024.216711.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38423245" target="_blank">38423245</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38306270">H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Leszczynska KB,
|
||
Freitas-Huhtamäki A,
|
||
Jayaprakash C,
|
||
Dzwigonska M,
|
||
Vitorino FNL,
|
||
Horth C,
|
||
Wojnicki K,
|
||
Gielniewski B,
|
||
Szadkowska P,
|
||
Kaza B,
|
||
Nazarian J,
|
||
Ciolkowski MK,
|
||
Trubicka J,
|
||
Grajkowska W,
|
||
Garcia BA,
|
||
Majewski J,
|
||
Kaminska B,
|
||
Mieczkowski J</span><br />
|
||
<span class="medgenPMjournal">Cell Rep</span>
|
||
2024 Feb 27;43(2):113707.
|
||
Epub 2024 Feb 1
|
||
doi: 10.1016/j.celrep.2024.113707.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38306270" target="_blank">38306270</a><a href="/pmc/articles/PMC11026119" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37934854">Tumor and immune cell types interact to produce heterogeneous phenotypes of pediatric high-grade glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">DeSisto J,
|
||
Donson AM,
|
||
Griesinger AM,
|
||
Fu R,
|
||
Riemondy K,
|
||
Mulcahy Levy J,
|
||
Siegenthaler JA,
|
||
Foreman NK,
|
||
Vibhakar R,
|
||
Green AL</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2024 Mar 4;26(3):538-552.
|
||
doi: 10.1093/neuonc/noad207.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37934854" target="_blank">37934854</a><a href="/pmc/articles/PMC10912009" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27006176">Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jakacki RI,
|
||
Cohen KJ,
|
||
Buxton A,
|
||
Krailo MD,
|
||
Burger PC,
|
||
Rosenblum MK,
|
||
Brat DJ,
|
||
Hamilton RL,
|
||
Eckel SP,
|
||
Zhou T,
|
||
Lavey RS,
|
||
Pollack IF</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2016 Oct;18(10):1442-50.
|
||
Epub 2016 Mar 22
|
||
doi: 10.1093/neuonc/now038.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27006176" target="_blank">27006176</a><a href="/pmc/articles/PMC5035517" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26448930">Molecular Biology in Pediatric High-Grade Glioma: Impact on Prognosis and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rizzo D,
|
||
Ruggiero A,
|
||
Martini M,
|
||
Rizzo V,
|
||
Maurizi P,
|
||
Riccardi R</span><br />
|
||
<span class="medgenPMjournal">Biomed Res Int</span>
|
||
2015;2015:215135.
|
||
Epub 2015 Sep 13
|
||
doi: 10.1155/2015/215135.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26448930" target="_blank">26448930</a><a href="/pmc/articles/PMC4584033" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pediatric%20high-grade%20glioma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (51)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38423245">Clinicopathological and molecular landscape of 5-year IDH-wild-type glioblastoma survivors: A multicentric retrospective study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Miele E,
|
||
Anghileri E,
|
||
Calatozzolo C,
|
||
Lazzarini E,
|
||
Patrizi S,
|
||
Ciolfi A,
|
||
Pedace L,
|
||
Patanè M,
|
||
Abballe L,
|
||
Paterra R,
|
||
Maddaloni L,
|
||
Barresi S,
|
||
Mastronuzzi A,
|
||
Petruzzi A,
|
||
Tramacere I,
|
||
Farinotti M,
|
||
Gurrieri L,
|
||
Pirola E,
|
||
Scarpelli M,
|
||
Lombardi G,
|
||
Villani V,
|
||
Simonelli M,
|
||
Merli R,
|
||
Salmaggi A,
|
||
Tartaglia M,
|
||
Silvani A,
|
||
DiMeco F,
|
||
Calistri D,
|
||
Lamperti E,
|
||
Locatelli F,
|
||
Indraccolo S,
|
||
Pollo B</span><br />
|
||
<span class="medgenPMjournal">Cancer Lett</span>
|
||
2024 Apr 28;588:216711.
|
||
Epub 2024 Feb 27
|
||
doi: 10.1016/j.canlet.2024.216711.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38423245" target="_blank">38423245</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37934854">Tumor and immune cell types interact to produce heterogeneous phenotypes of pediatric high-grade glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">DeSisto J,
|
||
Donson AM,
|
||
Griesinger AM,
|
||
Fu R,
|
||
Riemondy K,
|
||
Mulcahy Levy J,
|
||
Siegenthaler JA,
|
||
Foreman NK,
|
||
Vibhakar R,
|
||
Green AL</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2024 Mar 4;26(3):538-552.
|
||
doi: 10.1093/neuonc/noad207.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37934854" target="_blank">37934854</a><a href="/pmc/articles/PMC10912009" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37603953">Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Noll A,
|
||
Myers C,
|
||
Biery MC,
|
||
Meechan M,
|
||
Tahiri S,
|
||
Rajendran A,
|
||
Berens ME,
|
||
Paine D,
|
||
Byron S,
|
||
Zhang J,
|
||
Winter C,
|
||
Pakiam F,
|
||
Leary SES,
|
||
Cole BL,
|
||
Jackson ER,
|
||
Dun MD,
|
||
Foster JB,
|
||
Evans MK,
|
||
Pattwell SS,
|
||
Olson JM,
|
||
Vitanza NA</span><br />
|
||
<span class="medgenPMjournal">Neoplasia</span>
|
||
2023 Sep;43:100921.
|
||
Epub 2023 Aug 19
|
||
doi: 10.1016/j.neo.2023.100921.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37603953" target="_blank">37603953</a><a href="/pmc/articles/PMC10465940" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36961010">Spectroscopic MRI-Guided Proton Therapy in Non-Enhancing Pediatric High-Grade Glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang V,
|
||
Rejimon A,
|
||
Reddy K,
|
||
Trivedi AG,
|
||
Ramesh KK,
|
||
Giuffrida AS,
|
||
Muiruri R,
|
||
Shim H,
|
||
Eaton BR</span><br />
|
||
<span class="medgenPMjournal">Tomography</span>
|
||
2023 Mar 9;9(2):633-646.
|
||
doi: 10.3390/tomography9020051.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36961010" target="_blank">36961010</a><a href="/pmc/articles/PMC10037577" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34215733">Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">He C,
|
||
Xu K,
|
||
Zhu X,
|
||
Dunphy PS,
|
||
Gudenas B,
|
||
Lin W,
|
||
Twarog N,
|
||
Hover LD,
|
||
Kwon CH,
|
||
Kasper LH,
|
||
Zhang J,
|
||
Li X,
|
||
Dalton J,
|
||
Jonchere B,
|
||
Mercer KS,
|
||
Currier DG,
|
||
Caufield W,
|
||
Wang Y,
|
||
Xie J,
|
||
Broniscer A,
|
||
Wetmore C,
|
||
Upadhyaya SA,
|
||
Qaddoumi I,
|
||
Klimo P,
|
||
Boop F,
|
||
Gajjar A,
|
||
Zhang J,
|
||
Orr BA,
|
||
Robinson GW,
|
||
Monje M,
|
||
Freeman Iii BB,
|
||
Roussel MF,
|
||
Northcott PA,
|
||
Chen T,
|
||
Rankovic Z,
|
||
Wu G,
|
||
Chiang J,
|
||
Tinkle CL,
|
||
Shelat AA,
|
||
Baker SJ</span><br />
|
||
<span class="medgenPMjournal">Nat Commun</span>
|
||
2021 Jul 2;12(1):4089.
|
||
doi: 10.1038/s41467-021-24168-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34215733" target="_blank">34215733</a><a href="/pmc/articles/PMC8253809" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pediatric%20high-grade%20glioma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (40)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/35191733">Nimotuzumab as Additional Therapy for GLIOMA in Pediatric and Adolescent: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Parenrengi MA,
|
||
Suryaningtyas W,
|
||
Al Fauzi A,
|
||
Hafid Bajamal A,
|
||
Kusumastuti K,
|
||
Utomo B,
|
||
Muslim Hidayat Thamrin A,
|
||
Sulistiono B</span><br />
|
||
<span class="medgenPMjournal">Cancer Control</span>
|
||
2022 Jan-Dec;29:10732748211053927.
|
||
doi: 10.1177/10732748211053927.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35191733" target="_blank">35191733</a><a href="/pmc/articles/PMC8874160" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30544362">Impact of the H3K27M mutation on survival in pediatric high-grade glioma: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lu VM,
|
||
Alvi MA,
|
||
McDonald KL,
|
||
Daniels DJ</span><br />
|
||
<span class="medgenPMjournal">J Neurosurg Pediatr</span>
|
||
2019 Mar 1;23(3):308-316.
|
||
Epub 2018 Nov 30
|
||
doi: 10.3171/2018.9.PEDS18419.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30544362" target="_blank">30544362</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29204840">Survival outcomes in pediatric recurrent high-grade glioma: results of a 20-year systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kline C,
|
||
Felton E,
|
||
Allen IE,
|
||
Tahir P,
|
||
Mueller S</span><br />
|
||
<span class="medgenPMjournal">J Neurooncol</span>
|
||
2018 Mar;137(1):103-110.
|
||
Epub 2017 Dec 4
|
||
doi: 10.1007/s11060-017-2701-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29204840" target="_blank">29204840</a><a href="/pmc/articles/PMC5823744" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pediatric%20high-grade%20glioma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
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||
|
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|
||
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|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
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|
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|
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Pediatric%20high-grade%20glioma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet mgSection" id="ID_121">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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