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<meta name="keywords" content="C4021199, eeg with focal epileptiform discharges, finding, focal eeg abnormality, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="EEG discharges recorded in particular areas of a localized (focal) abnormality in cerebral electrical activity recorded along the scalp by electroencephalography (EEG)." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>EEG with focal epileptiform discharges (Concept Id: C4021199)
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<!--
UID=866845
ConceptID=C4021199
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">EEG with focal epileptiform discharges</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>866845</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C4021199</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>Focal EEG Abnormality</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0011185">HP:0011185</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">EEG discharges recorded in particular areas of a localized (focal) abnormality in cerebral electrical activity recorded along the scalp by electroencephalography (EEG). [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">EEG with focal epileptiform discharges</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/868417" ref="tree=MeSH" title="MedGen record for Abnormal nervous system physiology">Abnormal nervous system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/867410" ref="tree=MeSH" title="MedGen record for Abnormal nervous system electrophysiology">Abnormal nervous system electrophysiology</a></span><ul><li><span class="TLline"><a href="/medgen/868205" ref="tree=MeSH" title="MedGen record for Abnormality of central nervous system electrophysiology">Abnormality of central nervous system electrophysiology</a></span><ul><li><span class="TLline"><a href="/medgen/56235" ref="tree=MeSH" title="MedGen record for EEG abnormality">EEG abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/1377364" ref="tree=MeSH" title="MedGen record for Interictal EEG abnormality">Interictal EEG abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/869073" ref="tree=MeSH" title="MedGen record for Interictal epileptiform activity">Interictal epileptiform activity</a></span><ul><li><span class="matched_ds">EEG with focal epileptiform discharges</span><ul><li><span class="TLline"><a href="/medgen/1781579" ref="tree=MeSH" title="MedGen record for EEG with central epileptiform discharges">EEG with central epileptiform discharges</a></span><ul><li><span class="TLline"><a href="/medgen/868679" ref="tree=MeSH" title="MedGen record for EEG with central focal spike waves">EEG with central focal spike waves</a></span></li><li><span class="TLline"><a href="/medgen/868674" ref="tree=MeSH" title="MedGen record for EEG with central focal spikes">EEG with central focal spikes</a></span></li><li><span class="TLline"><a href="/medgen/869008" ref="tree=MeSH" title="MedGen record for EEG with central sharp slow waves">EEG with central sharp slow waves</a></span></li><li><span class="TLline"><a href="/medgen/777019" ref="tree=MeSH" title="MedGen record for EEG with central sharp waves">EEG with central sharp waves</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1782134" ref="tree=MeSH" title="MedGen record for EEG with centrotemporal epileptiform discharges">EEG with centrotemporal epileptiform discharges</a></span><ul><li><span class="TLline"><a href="/medgen/868454" ref="tree=MeSH" title="MedGen record for EEG with centrotemporal focal spike waves">EEG with centrotemporal focal spike waves</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/869061" ref="tree=MeSH" title="MedGen record for EEG with focal sharp slow waves">EEG with focal sharp slow waves</a></span></li><li><span class="TLline"><a href="/medgen/869060" ref="tree=MeSH" title="MedGen record for EEG with focal sharp waves">EEG with focal sharp waves</a></span></li><li><span class="TLline"><a href="/medgen/869059" ref="tree=MeSH" title="MedGen record for EEG with focal spike waves">EEG with focal spike waves</a></span></li><li><span class="TLline"><a href="/medgen/869063" ref="tree=MeSH" title="MedGen record for EEG with focal spikes">EEG with focal spikes</a></span><ul><li><span class="TLline"><a href="/medgen/869062" ref="tree=MeSH" title="MedGen record for EEG with series of focal spikes">EEG with series of focal spikes</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1782918" ref="tree=MeSH" title="MedGen record for EEG with frontal epileptiform discharges">EEG with frontal epileptiform discharges</a></span><ul><li><span class="TLline"><a href="/medgen/868678" ref="tree=MeSH" title="MedGen record for EEG with frontal focal spike waves">EEG with frontal focal spike waves</a></span></li><li><span class="TLline"><a href="/medgen/868673" ref="tree=MeSH" title="MedGen record for EEG with frontal focal spikes">EEG with frontal focal spikes</a></span></li><li><span class="TLline"><a href="/medgen/869009" ref="tree=MeSH" title="MedGen record for EEG with frontal sharp slow waves">EEG with frontal sharp slow waves</a></span></li><li><span class="TLline"><a href="/medgen/777014" ref="tree=MeSH" title="MedGen record for EEG with frontal sharp waves">EEG with frontal sharp waves</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1780269" ref="tree=MeSH" title="MedGen record for EEG with occipital epileptiform discharges">EEG with occipital epileptiform discharges</a></span><ul><li><span class="TLline"><a href="/medgen/868677" ref="tree=MeSH" title="MedGen record for EEG with occipital focal spike waves">EEG with occipital focal spike waves</a></span></li><li><span class="TLline"><a href="/medgen/868672" ref="tree=MeSH" title="MedGen record for EEG with occipital focal spikes">EEG with occipital focal spikes</a></span></li><li><span class="TLline"><a href="/medgen/869012" ref="tree=MeSH" title="MedGen record for EEG with occipital sharp slow waves">EEG with occipital sharp slow waves</a></span></li><li><span class="TLline"><a href="/medgen/777017" ref="tree=MeSH" title="MedGen record for EEG with occipital sharp waves">EEG with occipital sharp waves</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1780876" ref="tree=MeSH" title="MedGen record for EEG with parietal epileptiform discharges">EEG with parietal epileptiform discharges</a></span><ul><li><span class="TLline"><a href="/medgen/868676" ref="tree=MeSH" title="MedGen record for EEG with parietal focal spike waves">EEG with parietal focal spike waves</a></span></li><li><span class="TLline"><a href="/medgen/868671" ref="tree=MeSH" title="MedGen record for EEG with parietal focal spikes">EEG with parietal focal spikes</a></span></li><li><span class="TLline"><a href="/medgen/869011" ref="tree=MeSH" title="MedGen record for EEG with parietal sharp slow waves">EEG with parietal sharp slow waves</a></span></li><li><span class="TLline"><a href="/medgen/777016" ref="tree=MeSH" title="MedGen record for EEG with parietal sharp waves">EEG with parietal sharp waves</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1785327" ref="tree=MeSH" title="MedGen record for EEG with temporal epileptiform discharges">EEG with temporal epileptiform discharges</a></span><ul><li><span class="TLline"><a href="/medgen/868675" ref="tree=MeSH" title="MedGen record for EEG with temporal focal spike waves">EEG with temporal focal spike waves</a></span></li><li><span class="TLline"><a href="/medgen/868670" ref="tree=MeSH" title="MedGen record for EEG with temporal focal spikes">EEG with temporal focal spikes</a></span></li><li><span class="TLline"><a href="/medgen/869010" ref="tree=MeSH" title="MedGen record for EEG with temporal sharp slow waves">EEG with temporal sharp slow waves</a></span></li><li><span class="TLline"><a href="/medgen/777015" ref="tree=MeSH" title="MedGen record for EEG with temporal sharp waves">EEG with temporal sharp waves</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/869069" ref="tree=MeSH" title="MedGen record for Focal EEG discharges with propagation to ipsilateral hemisphere">Focal EEG discharges with propagation to ipsilateral hemisphere</a></span></li><li><span class="TLline"><a href="/medgen/869068" ref="tree=MeSH" title="MedGen record for Focal EEG discharges with secondary generalization">Focal EEG discharges with secondary generalization</a></span></li><li><span class="TLline"><a href="/medgen/869070" ref="tree=MeSH" title="MedGen record for Focal epileptiform discharges with limited propagation to contralateral hemisphere">Focal epileptiform discharges with limited propagation to contralateral hemisphere</a></span><ul><li><span class="TLline"><a href="/medgen/866860" ref="tree=MeSH" title="MedGen record for EEG with periodic lateralized epileptiform discharges">EEG with periodic lateralized epileptiform discharges</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/869042" ref="tree=MeSH" title="MedGen record for Hemihypsarrhythmia">Hemihypsarrhythmia</a></span></li><li><span class="TLline"><a href="/medgen/866864" ref="tree=MeSH" title="MedGen record for Multifocal epileptiform discharges">Multifocal epileptiform discharges</a></span><ul><li><span class="TLline"><a href="/medgen/869067" ref="tree=MeSH" title="MedGen record for Bilateral multifocal epileptiform discharges">Bilateral multifocal epileptiform discharges</a></span></li><li><span class="TLline"><a href="/medgen/869066" ref="tree=MeSH" title="MedGen record for Uni- and bilateral multifocal epileptiform discharges">Uni- and bilateral multifocal epileptiform discharges</a></span></li><li><span class="TLline"><a href="/medgen/869065" ref="tree=MeSH" title="MedGen record for Unilateral multifocal epileptiform discharges">Unilateral multifocal epileptiform discharges</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/869064" ref="tree=MeSH" title="MedGen record for Polymorphic focal epileptiform discharges">Polymorphic focal epileptiform discharges</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_1672905"><div><strong>Hypotonia, hypoventilation, impaired intellectual development, dysautonomia, epilepsy, and eye abnormalities</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1672905</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5193124</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Hypotonia, hypoventilation, impaired intellectual development, dysautonomia, epilepsy, and eye abnormalities (HIDEA) is an autosomal recessive neurodevelopmental syndrome characterized by global developmental delay, poor or absent speech, hypotonia, variable ocular movement and visual abnormalities, and respiratory difficulties, including hypoventilation, and sleep apnea. Patients may have significant breathing problems during respiratory infections that may lead to early death (summary by Rahikkala et al., 2019).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1672905">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1672905" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypotonia, hypoventilation, impaired intellectual development, dysautonomia, epilepsy, and eye abnormalities</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/37492027">Intraventricular SEEG and laser ablation for the treatment of infantile spasm: Technical note.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Xu X,
Wang Q,
Zhao Y,
Xu X,
Gan Z,
Zhang S,
Chen X</span><br />
<span class="medgenPMjournal">Brain Behav</span>
2023 Oct;13(10):e3184.
Epub 2023 Jul 26
doi: 10.1002/brb3.3184.
<span class="bold">PMID: </span><a href="/pubmed/37492027" target="_blank">37492027</a><a href="/pmc/articles/PMC10570471" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32563898">Expert opinion: Proposed diagnostic and treatment algorithms for Lennox-Gastaut syndrome in adult patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Montouris G,
Aboumatar S,
Burdette D,
Kothare S,
Kuzniecky R,
Rosenfeld W,
Chung S</span><br />
<span class="medgenPMjournal">Epilepsy Behav</span>
2020 Sep;110:107146.
Epub 2020 Jun 18
doi: 10.1016/j.yebeh.2020.107146.
<span class="bold">PMID: </span><a href="/pubmed/32563898" target="_blank">32563898</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27687685">Treatment of epilepsy in patients with Alzheimer's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Giorgi FS,
Guida M,
Vergallo A,
Bonuccelli U,
Zaccara G</span><br />
<span class="medgenPMjournal">Expert Rev Neurother</span>
2017 Mar;17(3):309-318.
Epub 2016 Oct 11
doi: 10.1080/14737175.2017.1243469.
<span class="bold">PMID: </span><a href="/pubmed/27687685" target="_blank">27687685</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(eeg%20with%20focal%20epileptiform%20discharges)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (16)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/38289522">EEG microstates show different features in focal epilepsy and psychogenic nonepileptic seizures.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kučikienė D,
Rajkumar R,
Timpte K,
Heckelmann J,
Neuner I,
Weber Y,
Wolking S</span><br />
<span class="medgenPMjournal">Epilepsia</span>
2024 Apr;65(4):974-983.
Epub 2024 Jan 30
doi: 10.1111/epi.17897.
<span class="bold">PMID: </span><a href="/pubmed/38289522" target="_blank">38289522</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36165814">Interictal and seizure-onset EEG patterns in malformations of cortical development: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shakhatreh L,
Janmohamed M,
Baker AA,
Willard A,
Laing J,
Rychkova M,
Chen Z,
Kwan P,
O'Brien TJ,
Perucca P</span><br />
<span class="medgenPMjournal">Neurobiol Dis</span>
2022 Nov;174:105863.
Epub 2022 Sep 19
doi: 10.1016/j.nbd.2022.105863.
<span class="bold">PMID: </span><a href="/pubmed/36165814" target="_blank">36165814</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34750097">Etiology and prognostic significance of ictal EEG patterns in patients with non-convulsive seizures.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Singh J,
Gopal M,
Amin A,
Peng J</span><br />
<span class="medgenPMjournal">Epileptic Disord</span>
2022 Feb 1;24(1):75-81.
doi: 10.1684/epd.2021.1363.
<span class="bold">PMID: </span><a href="/pubmed/34750097" target="_blank">34750097</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28882721">Clinical presentation of neurocysticercosis-related epilepsy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Duque KR,
Burneo JG</span><br />
<span class="medgenPMjournal">Epilepsy Behav</span>
2017 Nov;76:151-157.
Epub 2017 Sep 5
doi: 10.1016/j.yebeh.2017.08.008.
<span class="bold">PMID: </span><a href="/pubmed/28882721" target="_blank">28882721</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26341812">Clinical Impact of Epileptiform Discharge in Children With Attention-Deficit/Hyperactivity Disorder (ADHD).</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lee EH,
Choi YS,
Yoon HS,
Bahn GH</span><br />
<span class="medgenPMjournal">J Child Neurol</span>
2016 Apr;31(5):584-8.
Epub 2015 Sep 4
doi: 10.1177/0883073815604223.
<span class="bold">PMID: </span><a href="/pubmed/26341812" target="_blank">26341812</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EEG%20with%20focal%20epileptiform%20discharges%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (543)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38116690">Learn how to interpret and use intracranial EEG findings.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Frauscher B,
Mansilla D,
Abdallah C,
Astner-Rohracher A,
Beniczky S,
Brazdil M,
Gnatkovsky V,
Jacobs J,
Kalamangalam G,
Perucca P,
Ryvlin P,
Schuele S,
Tao J,
Wang Y,
Zijlmans M,
McGonigal A</span><br />
<span class="medgenPMjournal">Epileptic Disord</span>
2024 Feb;26(1):1-59.
Epub 2024 Feb 13
doi: 10.1002/epd2.20190.
<span class="bold">PMID: </span><a href="/pubmed/38116690" target="_blank">38116690</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32563898">Expert opinion: Proposed diagnostic and treatment algorithms for Lennox-Gastaut syndrome in adult patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Montouris G,
Aboumatar S,
Burdette D,
Kothare S,
Kuzniecky R,
Rosenfeld W,
Chung S</span><br />
<span class="medgenPMjournal">Epilepsy Behav</span>
2020 Sep;110:107146.
Epub 2020 Jun 18
doi: 10.1016/j.yebeh.2020.107146.
<span class="bold">PMID: </span><a href="/pubmed/32563898" target="_blank">32563898</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30921017">Electroencephalography in Epilepsy Evaluation.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chen H,
Koubeissi MZ</span><br />
<span class="medgenPMjournal">Continuum (Minneap Minn)</span>
2019 Apr;25(2):431-453.
doi: 10.1212/CON.0000000000000705.
<span class="bold">PMID: </span><a href="/pubmed/30921017" target="_blank">30921017</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22925838">Fixation-off sensitivity.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Brigo F,
Rossini F,
Stefani A,
Nardone R,
Tezzon F,
Fiaschi A,
Manganotti P,
Bongiovanni LG</span><br />
<span class="medgenPMjournal">Clin Neurophysiol</span>
2013 Feb;124(2):221-7.
Epub 2012 Aug 24
doi: 10.1016/j.clinph.2012.07.017.
<span class="bold">PMID: </span><a href="/pubmed/22925838" target="_blank">22925838</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21349720">Frontal lobe epilepsy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Beleza P,
Pinho J</span><br />
<span class="medgenPMjournal">J Clin Neurosci</span>
2011 May;18(5):593-600.
Epub 2011 Feb 23
doi: 10.1016/j.jocn.2010.08.018.
<span class="bold">PMID: </span><a href="/pubmed/21349720" target="_blank">21349720</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EEG%20with%20focal%20epileptiform%20discharges%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (706)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/38806855">Attention deficit hyperactivity disorder in children with epilepsy: a multicenter cross-sectional analysis in China.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Pan G,
Han Y,
Wang TC,
Chen ZY,
Wang XQ,
Sun HB,
Liu YH,
Wang Q,
Lin WH,
Li JM,
Zhou SZ,
Zhang YH</span><br />
<span class="medgenPMjournal">World J Pediatr</span>
2024 Oct;20(10):1070-1078.
Epub 2024 May 28
doi: 10.1007/s12519-024-00813-2.
<span class="bold">PMID: </span><a href="/pubmed/38806855" target="_blank">38806855</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38605017">Multisensory flicker modulates widespread brain networks and reduces interictal epileptiform discharges.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blanpain LT,
Cole ER,
Chen E,
Park JK,
Walelign MY,
Gross RE,
Cabaniss BT,
Willie JT,
Singer AC</span><br />
<span class="medgenPMjournal">Nat Commun</span>
2024 Apr 11;15(1):3156.
doi: 10.1038/s41467-024-47263-y.
<span class="bold">PMID: </span><a href="/pubmed/38605017" target="_blank">38605017</a><a href="/pmc/articles/PMC11009358" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34750097">Etiology and prognostic significance of ictal EEG patterns in patients with non-convulsive seizures.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Singh J,
Gopal M,
Amin A,
Peng J</span><br />
<span class="medgenPMjournal">Epileptic Disord</span>
2022 Feb 1;24(1):75-81.
doi: 10.1684/epd.2021.1363.
<span class="bold">PMID: </span><a href="/pubmed/34750097" target="_blank">34750097</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32563898">Expert opinion: Proposed diagnostic and treatment algorithms for Lennox-Gastaut syndrome in adult patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Montouris G,
Aboumatar S,
Burdette D,
Kothare S,
Kuzniecky R,
Rosenfeld W,
Chung S</span><br />
<span class="medgenPMjournal">Epilepsy Behav</span>
2020 Sep;110:107146.
Epub 2020 Jun 18
doi: 10.1016/j.yebeh.2020.107146.
<span class="bold">PMID: </span><a href="/pubmed/32563898" target="_blank">32563898</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31185363">Periodic focal epileptiform discharges.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tatum WO,
Feyissa AM,
ReFaey K,
Grewal SS,
Alvi MA,
Castro-Apolo R,
Roth G,
Segura-Duran I,
Mahato D,
Ruiz-Garcia H,
Pamias-Portalatin E,
Yelvington K,
Chaichana K,
Bechtle P,
Quinones-Hinojosa A</span><br />
<span class="medgenPMjournal">Clin Neurophysiol</span>
2019 Aug;130(8):1320-1328.
Epub 2019 May 31
doi: 10.1016/j.clinph.2019.04.718.
<span class="bold">PMID: </span><a href="/pubmed/31185363" target="_blank">31185363</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EEG%20with%20focal%20epileptiform%20discharges%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (217)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38116690">Learn how to interpret and use intracranial EEG findings.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Frauscher B,
Mansilla D,
Abdallah C,
Astner-Rohracher A,
Beniczky S,
Brazdil M,
Gnatkovsky V,
Jacobs J,
Kalamangalam G,
Perucca P,
Ryvlin P,
Schuele S,
Tao J,
Wang Y,
Zijlmans M,
McGonigal A</span><br />
<span class="medgenPMjournal">Epileptic Disord</span>
2024 Feb;26(1):1-59.
Epub 2024 Feb 13
doi: 10.1002/epd2.20190.
<span class="bold">PMID: </span><a href="/pubmed/38116690" target="_blank">38116690</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37798769">The spectrum of sepsis-associated encephalopathy: a clinical perspective.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sonneville R,
Benghanem S,
Jeantin L,
de Montmollin E,
Doman M,
Gaudemer A,
Thy M,
Timsit JF</span><br />
<span class="medgenPMjournal">Crit Care</span>
2023 Oct 5;27(1):386.
doi: 10.1186/s13054-023-04655-8.
<span class="bold">PMID: </span><a href="/pubmed/37798769" target="_blank">37798769</a><a href="/pmc/articles/PMC10552444" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21156385">Directed differential connectivity graph of interictal epileptiform discharges.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Amini L,
Jutten C,
Achard S,
David O,
Soltanian-Zadeh H,
Hossein-Zadeh GA,
Kahane P,
Minotti L,
Vercueil L</span><br />
<span class="medgenPMjournal">IEEE Trans Biomed Eng</span>
2011 Apr;58(4):884-93.
Epub 2010 Dec 13
doi: 10.1109/TBME.2010.2099227.
<span class="bold">PMID: </span><a href="/pubmed/21156385" target="_blank">21156385</a><a href="/pmc/articles/PMC3368827" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12060012">Is it status?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Brenner RP</span><br />
<span class="medgenPMjournal">Epilepsia</span>
2002;43 Suppl 3:103-13.
doi: 10.1046/j.1528-1157.43.s.3.9.x.
<span class="bold">PMID: </span><a href="/pubmed/12060012" target="_blank">12060012</a></div>
<div class="nl"><a target="_blank" href="/pubmed/2050815">Principles of magnetoencephalography.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sato S,
Balish M,
Muratore R</span><br />
<span class="medgenPMjournal">J Clin Neurophysiol</span>
1991 Apr;8(2):144-56.
doi: 10.1097/00004691-199104000-00003.
<span class="bold">PMID: </span><a href="/pubmed/2050815" target="_blank">2050815</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EEG%20with%20focal%20epileptiform%20discharges%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (333)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37099548">The clinical features of familial focal epilepsy with variable foci and NPRL3 gene variant.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Y,
Yu P,
Zhu G,
Wu X,
Ding D,
Hong Z</span><br />
<span class="medgenPMjournal">PLoS One</span>
2023;18(4):e0284924.
Epub 2023 Apr 26
doi: 10.1371/journal.pone.0284924.
<span class="bold">PMID: </span><a href="/pubmed/37099548" target="_blank">37099548</a><a href="/pmc/articles/PMC10132533" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31307599">Focal epilepsies and focal disorders.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lagarde S,
Bartolomei F</span><br />
<span class="medgenPMjournal">Handb Clin Neurol</span>
2019;161:17-43.
doi: 10.1016/B978-0-444-64142-7.00039-4.
<span class="bold">PMID: </span><a href="/pubmed/31307599" target="_blank">31307599</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28766469">The forsaking of the clinical EEG by psychiatry: how justified?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Boutros NN</span><br />
<span class="medgenPMjournal">CNS Spectr</span>
2018 Jun;23(3):196-204.
Epub 2017 Aug 2
doi: 10.1017/S1092852917000505.
<span class="bold">PMID: </span><a href="/pubmed/28766469" target="_blank">28766469</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22925838">Fixation-off sensitivity.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Brigo F,
Rossini F,
Stefani A,
Nardone R,
Tezzon F,
Fiaschi A,
Manganotti P,
Bongiovanni LG</span><br />
<span class="medgenPMjournal">Clin Neurophysiol</span>
2013 Feb;124(2):221-7.
Epub 2012 Aug 24
doi: 10.1016/j.clinph.2012.07.017.
<span class="bold">PMID: </span><a href="/pubmed/22925838" target="_blank">22925838</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21156385">Directed differential connectivity graph of interictal epileptiform discharges.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Amini L,
Jutten C,
Achard S,
David O,
Soltanian-Zadeh H,
Hossein-Zadeh GA,
Kahane P,
Minotti L,
Vercueil L</span><br />
<span class="medgenPMjournal">IEEE Trans Biomed Eng</span>
2011 Apr;58(4):884-93.
Epub 2010 Dec 13
doi: 10.1109/TBME.2010.2099227.
<span class="bold">PMID: </span><a href="/pubmed/21156385" target="_blank">21156385</a><a href="/pmc/articles/PMC3368827" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EEG%20with%20focal%20epileptiform%20discharges%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (438)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/36165814">Interictal and seizure-onset EEG patterns in malformations of cortical development: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shakhatreh L,
Janmohamed M,
Baker AA,
Willard A,
Laing J,
Rychkova M,
Chen Z,
Kwan P,
O'Brien TJ,
Perucca P</span><br />
<span class="medgenPMjournal">Neurobiol Dis</span>
2022 Nov;174:105863.
Epub 2022 Sep 19
doi: 10.1016/j.nbd.2022.105863.
<span class="bold">PMID: </span><a href="/pubmed/36165814" target="_blank">36165814</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33121875">Systematic review of EEG findings in 617 patients diagnosed with COVID-19.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Antony AR,
Haneef Z</span><br />
<span class="medgenPMjournal">Seizure</span>
2020 Dec;83:234-241.
Epub 2020 Oct 19
doi: 10.1016/j.seizure.2020.10.014.
<span class="bold">PMID: </span><a href="/pubmed/33121875" target="_blank">33121875</a><a href="/pmc/articles/PMC7569418" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32957032">Electroencephalographic findings in COVID-19 patients: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Roberto KT,
Espiritu AI,
Fernandez MLL,
Gutierrez JC</span><br />
<span class="medgenPMjournal">Seizure</span>
2020 Nov;82:17-22.
Epub 2020 Sep 15
doi: 10.1016/j.seizure.2020.09.007.
<span class="bold">PMID: </span><a href="/pubmed/32957032" target="_blank">32957032</a><a href="/pmc/articles/PMC7490625" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28034485">The 'Photosensitivity Model' is (also) a model for focal (partial) seizures.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kasteleijn-Nolst Trenite D,
Genton P,
Brandt C,
Reed RC</span><br />
<span class="medgenPMjournal">Epilepsy Res</span>
2017 Jul;133:113-120.
Epub 2016 Dec 2
doi: 10.1016/j.eplepsyres.2016.11.012.
<span class="bold">PMID: </span><a href="/pubmed/28034485" target="_blank">28034485</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27513825">Transcranial magnetic stimulation for the treatment of epilepsy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chen R,
Spencer DC,
Weston J,
Nolan SJ</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2016 Aug 11;(8):CD011025.
doi: 10.1002/14651858.CD011025.pub2.
<span class="bold">PMID: </span><a href="/pubmed/27513825" target="_blank">27513825</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EEG%20with%20focal%20epileptiform%20discharges%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (9)</a></div></div>
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