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<meta name="keywords" content="C3280266, disease or syndrome, mog, mog narcolepsy, narcolepsy 7, narcolepsy caused by mutation in mog, narcolepsy type 7, nrclp7, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Some people with narcolepsy have all of the major features of the disorder, while others have only one or two. Most of the signs and symptoms persist throughout life, although episodes of cataplexy may become less frequent with age and treatment.\n\nAnother common feature of narcolepsy is cataplexy, which is a sudden loss of muscle tone in response to strong emotion (such as laughing, surprise, or anger). These episodes of muscle weakness can cause an affected person to slump over or fall, which occasionally leads to injury. Episodes of cataplexy usually last just a few seconds, and they may occur from several times a day to a few times a year. Most people diagnosed with narcolepsy also have cataplexy. However, some do not, which has led researchers to distinguish two major forms of the condition: narcolepsy with cataplexy and narcolepsy without cataplexy.\n\nNarcolepsy also affects nighttime sleep. Most affected individuals have trouble sleeping for more than a few hours at night. They often experience vivid hallucinations while falling asleep (hypnogogic hallucinations) or while waking up (hypnopompic hallucinations). Affected individuals often have realistic and distressing dreams, and they may act out their dreams by moving excessively or talking in their sleep. Many people with narcolepsy also experience sleep paralysis, which is an inability to move or speak for a short period while falling asleep or awakening. The combination of hallucinations, vivid dreams, and sleep paralysis is often frightening and unpleasant for affected individuals.\n\nNarcolepsy is characterized by excessive daytime sleepiness. Affected individuals feel tired during the day, and several times a day they may experience an overwhelming urge to sleep. "Sleep attacks" can occur at unusual times, such as during a meal or in the middle of a conversation. They last from a few seconds to a few minutes and often lead to a longer nap, after which affected individuals wake up feeling refreshed.\n\nNarcolepsy is a chronic sleep disorder that disrupts the normal sleep-wake cycle. Although this condition can appear at any age, it most often begins in adolescence." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=481896
|
||
ConceptID=C3280266
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Narcolepsy 7<span class="h1sub">(NRCLP7)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>481896</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C3280266</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>NRCLP7</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="MOG - ID: 4340 - NCBI Gene" href="/gene/4340" class="medgenPMinfo">MOG</a> (6p22.1)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0013652" target="_blank">MONDO:0013652</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/614250" target="_blank">614250</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Some people with narcolepsy have all of the major features of the disorder, while others have only one or two. Most of the signs and symptoms persist throughout life, although episodes of cataplexy may become less frequent with age and treatment.<br /><br />Another common feature of narcolepsy is cataplexy, which is a sudden loss of muscle tone in response to strong emotion (such as laughing, surprise, or anger). These episodes of muscle weakness can cause an affected person to slump over or fall, which occasionally leads to injury. Episodes of cataplexy usually last just a few seconds, and they may occur from several times a day to a few times a year. Most people diagnosed with narcolepsy also have cataplexy. However, some do not, which has led researchers to distinguish two major forms of the condition: narcolepsy with cataplexy and narcolepsy without cataplexy.<br /><br />Narcolepsy also affects nighttime sleep. Most affected individuals have trouble sleeping for more than a few hours at night. They often experience vivid hallucinations while falling asleep (hypnogogic hallucinations) or while waking up (hypnopompic hallucinations). Affected individuals often have realistic and distressing dreams, and they may act out their dreams by moving excessively or talking in their sleep. Many people with narcolepsy also experience sleep paralysis, which is an inability to move or speak for a short period while falling asleep or awakening. The combination of hallucinations, vivid dreams, and sleep paralysis is often frightening and unpleasant for affected individuals.<br /><br />Narcolepsy is characterized by excessive daytime sleepiness. Affected individuals feel tired during the day, and several times a day they may experience an overwhelming urge to sleep. "Sleep attacks" can occur at unusual times, such as during a meal or in the middle of a conversation. They last from a few seconds to a few minutes and often lead to a longer nap, after which affected individuals wake up feeling refreshed.<br /><br />Narcolepsy is a chronic sleep disorder that disrupts the normal sleep-wake cycle. Although this condition can appear at any age, it most often begins in adolescence. [from <a title="MedlinePlus Genetics" href="https://medlineplus.gov/genetics/" class="defSource" target="_blank">MedlinePlus Genetics</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_18127"><div><strong>Obesity</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>18127</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0028754</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Accumulation of substantial excess body fat.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/18127">Feature record</a> | <a href="/medgen?term=%22Obesity%22%5BClinical%20Features%5D%20OR%2018127%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_2862"><div><strong>Cataplexy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>2862</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0007384</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A sudden and transient episode of bilateral loss of muscle tone, often triggered by emotions.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/2862">Feature record</a> | <a href="/medgen?term=%22Cataplexy%22%5BClinical%20Features%5D%20OR%202862%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_45001"><div><strong>Narcolepsy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>45001</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0027404</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An abnormal phenomenon characterized by a classic tetrad of excessive daytime sleepiness with irresistible sleep attacks, cataplexy (sudden bilateral loss of muscle tone), hypnagogic hallucinations, and sleep paralysis.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/45001">Feature record</a> | <a href="/medgen?term=%22Narcolepsy%22%5BClinical%20Features%5D%20OR%2045001%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_68578"><div><strong>Hypnagogic hallucination</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>68578</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0233773</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Sign or Symptom</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hypnagogic hallucinations are brief hallucinations that occur as you are falling asleep.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/68578">Feature record</a> | <a href="/medgen?term=%22Hypnagogic%20hallucination%22%5BClinical%20Features%5D%20OR%2068578%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_96820"><div><strong>Sleep paralysis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>96820</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0456511</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An inability to move the body at the onset of sleep or upon awakening from sleep, lasting for seconds to a few minutes.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/96820">Feature record</a> | <a href="/medgen?term=%22Sleep%20paralysis%22%5BClinical%20Features%5D%20OR%2096820%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_101045"><div><strong>Obstructive sleep apnea syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>101045</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0520679</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Obstructive sleep apnea is a common, chronic, complex disease associated with serious cardiovascular and neuropsychologic sequelae and with substantial social and economic costs (Palmer et al., 2003).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/101045">Feature record</a> | <a href="/medgen?term=%22Obstructive%20sleep%20apnea%20syndrome%22%5BClinical%20Features%5D%20OR%20101045%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_1635612"><div><strong>Excessive daytime somnolence</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1635612</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551761</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Sign or Symptom</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A state of abnormally strong desire for sleep during the daytime.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1635612">Feature record</a> | <a href="/medgen?term=%22Excessive%20daytime%20somnolence%22%5BClinical%20Features%5D%20OR%201635612%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_41523"><div><strong>Type 2 diabetes mellitus</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>41523</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0011860</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">WFS1 spectrum disorder (WFS1-SD) comprises classic WFS1 spectrum disorder and nonclassic WFS1 spectrum disorder. Classic WFS1-SD, a progressive neurodegenerative disorder, is characterized by onset of diabetes mellitus and optic atrophy before age 16 years. Additional complications may include one or more of the following: variable hearing impairment / deafness, diabetes insipidus, neurologic abnormalities, neurogenic bladder, and psychiatric abnormalities. Nonclassic WFS1-SD is less common than classic WFS1-SD. Phenotypes that appear to be milder than classic WFS1-SD include: optic atrophy and hearing impairment; neonatal diabetes, profound congenital deafness, and cataracts; isolated diabetes mellitus; isolated congenital cataracts; and isolated congenital, slowly progressive, and low-frequency (<2000 Hz) sensorineural hearing loss.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/41523">Feature record</a> | <a href="/medgen?term=%22Type%202%20diabetes%20mellitus%22%5BClinical%20Features%5D%20OR%2041523%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of metabolism/homeostasis</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_41523" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Type 2 diabetes mellitus</a></span></li></ul></li><li><span class="TLline">Abnormality of the nervous system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_2862" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cataplexy</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_1635612" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Excessive daytime somnolence</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_68578" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypnagogic hallucination</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_45001" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Narcolepsy</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_101045" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Obstructive sleep apnea syndrome</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_96820" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Sleep paralysis</a></span></li></ul></li><li><span class="TLline">Growth abnormality</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_18127" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Obesity</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33882756">Solriamfetol for the Management of Excessive Daytime Sleepiness.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cuomo MC,
|
||
Sheehan AH,
|
||
Jordan JK</span><br />
|
||
<span class="medgenPMjournal">J Pharm Pract</span>
|
||
2022 Dec;35(6):963-970.
|
||
Epub 2021 Apr 22
|
||
doi: 10.1177/08971900211009080.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33882756" target="_blank">33882756</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22narcolepsy%207%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36881684">Pediatric sleep: current knowledge, gaps, and opportunities for the future.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reynolds AM,
|
||
Spaeth AM,
|
||
Hale L,
|
||
Williamson AA,
|
||
LeBourgeois MK,
|
||
Wong SD,
|
||
Hartstein LE,
|
||
Levenson JC,
|
||
Kwon M,
|
||
Hart CN,
|
||
Greer A,
|
||
Richardson CE,
|
||
Gradisar M,
|
||
Clementi MA,
|
||
Simon SL,
|
||
Reuter-Yuill LM,
|
||
Picchietti DL,
|
||
Wild S,
|
||
Tarokh L,
|
||
Sexton-Radek K,
|
||
Malow BA,
|
||
Lenker KP,
|
||
Calhoun SL,
|
||
Johnson DA,
|
||
Lewin D,
|
||
Carskadon MA</span><br />
|
||
<span class="medgenPMjournal">Sleep</span>
|
||
2023 Jul 11;46(7)
|
||
doi: 10.1093/sleep/zsad060.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36881684" target="_blank">36881684</a><a href="/pmc/articles/PMC10334737" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36515157">Management of REM sleep behavior disorder: an American Academy of Sleep Medicine clinical practice guideline.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Howell M,
|
||
Avidan AY,
|
||
Foldvary-Schaefer N,
|
||
Malkani RG,
|
||
During EH,
|
||
Roland JP,
|
||
McCarter SJ,
|
||
Zak RS,
|
||
Carandang G,
|
||
Kazmi U,
|
||
Ramar K</span><br />
|
||
<span class="medgenPMjournal">J Clin Sleep Med</span>
|
||
2023 Apr 1;19(4):759-768.
|
||
doi: 10.5664/jcsm.10424.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36515157" target="_blank">36515157</a><a href="/pmc/articles/PMC10071384" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33607035">Real-time dialogue between experimenters and dreamers during REM sleep.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Konkoly KR,
|
||
Appel K,
|
||
Chabani E,
|
||
Mangiaruga A,
|
||
Gott J,
|
||
Mallett R,
|
||
Caughran B,
|
||
Witkowski S,
|
||
Whitmore NW,
|
||
Mazurek CY,
|
||
Berent JB,
|
||
Weber FD,
|
||
Türker B,
|
||
Leu-Semenescu S,
|
||
Maranci JB,
|
||
Pipa G,
|
||
Arnulf I,
|
||
Oudiette D,
|
||
Dresler M,
|
||
Paller KA</span><br />
|
||
<span class="medgenPMjournal">Curr Biol</span>
|
||
2021 Apr 12;31(7):1417-1427.e6.
|
||
Epub 2021 Feb 18
|
||
doi: 10.1016/j.cub.2021.01.026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33607035" target="_blank">33607035</a><a href="/pmc/articles/PMC8162929" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27250813">The Development of Sleep Medicine: A Historical Sketch.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schulz H,
|
||
Salzarulo P</span><br />
|
||
<span class="medgenPMjournal">J Clin Sleep Med</span>
|
||
2016 Jul 15;12(7):1041-52.
|
||
doi: 10.5664/jcsm.5946.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27250813" target="_blank">27250813</a><a href="/pmc/articles/PMC4918987" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12849366">The hypothalamus in episodic brain disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Overeem S,
|
||
van Vliet JA,
|
||
Lammers GJ,
|
||
Zitman FG,
|
||
Swaab DF,
|
||
Ferrari MD</span><br />
|
||
<span class="medgenPMjournal">Lancet Neurol</span>
|
||
2002 Nov;1(7):437-44.
|
||
doi: 10.1016/s1474-4422(02)00191-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12849366" target="_blank">12849366</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Narcolepsy%207%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (450)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37634997">Narcolepsies, update in 2023.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barateau L,
|
||
Pizza F,
|
||
Chenini S,
|
||
Peter-Derex L,
|
||
Dauvilliers Y</span><br />
|
||
<span class="medgenPMjournal">Rev Neurol (Paris)</span>
|
||
2023 Oct;179(7):727-740.
|
||
Epub 2023 Aug 25
|
||
doi: 10.1016/j.neurol.2023.08.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37634997" target="_blank">37634997</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37598089">Sleepiness in neurological disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dubessy AL,
|
||
Arnulf I</span><br />
|
||
<span class="medgenPMjournal">Rev Neurol (Paris)</span>
|
||
2023 Oct;179(7):755-766.
|
||
Epub 2023 Aug 17
|
||
doi: 10.1016/j.neurol.2023.07.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37598089" target="_blank">37598089</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31004212">Update on narcolepsy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reading PJ</span><br />
|
||
<span class="medgenPMjournal">J Neurol</span>
|
||
2019 Jul;266(7):1809-1815.
|
||
Epub 2019 Apr 19
|
||
doi: 10.1007/s00415-019-09310-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31004212" target="_blank">31004212</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24816752">Metabolic consequences of sleep and circadian disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Depner CM,
|
||
Stothard ER,
|
||
Wright KP Jr</span><br />
|
||
<span class="medgenPMjournal">Curr Diab Rep</span>
|
||
2014 Jul;14(7):507.
|
||
doi: 10.1007/s11892-014-0507-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24816752" target="_blank">24816752</a><a href="/pmc/articles/PMC4308960" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21807160">Hypersomnia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Freedom T</span><br />
|
||
<span class="medgenPMjournal">Dis Mon</span>
|
||
2011 Jul;57(7):353-63.
|
||
doi: 10.1016/j.disamonth.2011.04.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21807160" target="_blank">21807160</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Narcolepsy%207%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (415)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36515157">Management of REM sleep behavior disorder: an American Academy of Sleep Medicine clinical practice guideline.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Howell M,
|
||
Avidan AY,
|
||
Foldvary-Schaefer N,
|
||
Malkani RG,
|
||
During EH,
|
||
Roland JP,
|
||
McCarter SJ,
|
||
Zak RS,
|
||
Carandang G,
|
||
Kazmi U,
|
||
Ramar K</span><br />
|
||
<span class="medgenPMjournal">J Clin Sleep Med</span>
|
||
2023 Apr 1;19(4):759-768.
|
||
doi: 10.5664/jcsm.10424.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36515157" target="_blank">36515157</a><a href="/pmc/articles/PMC10071384" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33417072">γ-Hydroxybutyric Acid: Pharmacokinetics, Pharmacodynamics, and Toxicology.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Felmlee MA,
|
||
Morse BL,
|
||
Morris ME</span><br />
|
||
<span class="medgenPMjournal">AAPS J</span>
|
||
2021 Jan 8;23(1):22.
|
||
doi: 10.1208/s12248-020-00543-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33417072" target="_blank">33417072</a><a href="/pmc/articles/PMC8098080" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30694576">A randomized study of solriamfetol for excessive sleepiness in narcolepsy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Thorpy MJ,
|
||
Shapiro C,
|
||
Mayer G,
|
||
Corser BC,
|
||
Emsellem H,
|
||
Plazzi G,
|
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<div class="nl"><a target="_blank" href="/pubmed/34743789">Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine clinical practice guideline.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/18565458">CSF hypocretin-1 assessment in sleep and neurological disorders.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Bourgin P,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Narcolepsy%207%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (148)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/31004212">Update on narcolepsy.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/27250813">The Development of Sleep Medicine: A Historical Sketch.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/18565458">CSF hypocretin-1 assessment in sleep and neurological disorders.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Bourgin P,
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Mignot E</span><br />
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Narcolepsy%207%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (324)</a></div></div>
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||
</div>
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||
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||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/35820399">Heterogeneity in Estimates of Incidence and Prevalence of Narcolepsy: A Systematic Review and Meta-Regression Analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Wang Y,
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Chen Y,
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Tong Y,
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Li C,
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Li J,
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Epub 2022 Jul 12
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doi: 10.1159/000525282.
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<span class="bold">PMID: </span><a href="/pubmed/35820399" target="_blank">35820399</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34893148">Month of birth and the risk of narcolepsy: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hsu CW,
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Tseng PT,
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Tu YK,
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Lin PY,
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Wang LJ,
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Hung CF,
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Yang YH,
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Kao HY,
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Yeh CB,
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Lai HC,
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Chen TY</span><br />
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<span class="medgenPMjournal">J Clin Sleep Med</span>
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2022 Apr 1;18(4):1113-1120.
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doi: 10.5664/jcsm.9816.
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<span class="bold">PMID: </span><a href="/pubmed/34893148" target="_blank">34893148</a><a href="/pmc/articles/PMC8974386" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34743789">Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine clinical practice guideline.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Maski K,
|
||
Trotti LM,
|
||
Kotagal S,
|
||
Robert Auger R,
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Rowley JA,
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Hashmi SD,
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||
Watson NF</span><br />
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<span class="medgenPMjournal">J Clin Sleep Med</span>
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2021 Sep 1;17(9):1881-1893.
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doi: 10.5664/jcsm.9328.
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<span class="bold">PMID: </span><a href="/pubmed/34743789" target="_blank">34743789</a><a href="/pmc/articles/PMC8636351" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33740593">Metabolic profile in patients with narcolepsy: a systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Mohammadi S,
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Moosaie F,
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Saghazadeh A,
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Mahmoudi M,
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Rezaei N</span><br />
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<span class="medgenPMjournal">Sleep Med</span>
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2021 May;81:268-284.
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||
Epub 2021 Feb 24
|
||
doi: 10.1016/j.sleep.2021.02.040.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33740593" target="_blank">33740593</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28847694">Incidence of narcolepsy after H1N1 influenza and vaccinations: Systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sarkanen TO,
|
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Alakuijala APE,
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Dauvilliers YA,
|
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Partinen MM</span><br />
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<span class="medgenPMjournal">Sleep Med Rev</span>
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<span class="bold">PMID: </span><a href="/pubmed/28847694" target="_blank">28847694</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Narcolepsy%207%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (17)</a></div></div>
|
||
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|
||
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C3280266%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C3280266%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (3)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C3280266%5bDISCUI%5d" target="_blank">See all (3)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=614250" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Narcolepsy%207" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22narcolepsy%207%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Narcolepsy%207%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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|
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<div class="portlet mgSection" id="ID_115">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Molecular_resources">Molecular resources</h1><a sid="115" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=159465" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=4340[geneid]" target="_blank">View MOG variations in ClinVar</a></li><li><a href="https://catalog.coriell.org/Search?q=614250" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
|
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<div class="portlet_content ln"><ul><li><a href="http://www.diseaseinfosearch.org/Narcolepsy+7/8970" target="_blank">Genetic Alliance</a></li><li><a href="https://www.malacards.org/card/narcolepsy_7" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Narcolepsy%207" target="_blank">MedlinePlus</a></li><li><a href="https://medlineplus.gov/genetics/condition/narcolepsy" target="_blank">MedlinePlusGenetics (GHR)</a></li><li><a href="https://rarediseases.info.nih.gov/diseases/15783/disease" target="_blank">NCATS Office of Rare Diseases Research (GARD)</a></li></ul></div>
|
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<a href="/pubmed/clinical?term=Narcolepsy%207" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67cd387484f3725e59ddfcbb">Narcolepsy 7</a>
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<div class="ralinkpop offscreen_noflow">Narcolepsy 7<div class="brieflinkpopdesc"></div></div>
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<a class="htb" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67cd387384f3725e59ddf388">C3280266[conceptid] <span class="number">(1)</span></a>
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<a class="htb" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67cd3872f4a390645eec7404">C1834372[trait identifier] AND "OMIM"[submitter] <span class="number">(1)</span></a>
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<div class="tertiary">ClinVar</div>
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<div class="tertiary">MedGen</div>
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<a class="htb" ref="log$=activity&linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67cd3870b15b832ebca19176">C1834372[conceptid] <span class="number">(1)</span></a>
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