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<meta name="keywords" content="C2751607, atfb8, atrial fibrillation, familial, 8, disease or syndrome, zfhx3, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Atrial fibrillation is the most common sustained cardiac rhythm disturbance, affecting more than 2 million Americans, with an overall prevalence of 0.89%. The prevalence increases rapidly with age, to 2.3% between the ages of 40 and 60 years, and to 5.9% over the age of 65. The most dreaded complication is thromboembolic stroke (Brugada et al., 1997). For a discussion of genetic heterogeneity of atrial fibrillation, see 608583." /><meta name="robots" content="index,nofollow,noarchive" />
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|
||
<!--
|
||
UID=414420
|
||
ConceptID=C2751607
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Atrial fibrillation, familial, 8<span class="h1sub">(ATFB8)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>414420</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C2751607</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>ATFB8</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="ZFHX3 - ID: 463 - NCBI Gene" href="/gene/463" class="medgenPMinfo">ZFHX3</a> (16q22.2-22.3)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0013100" target="_blank">MONDO:0013100</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/613055" target="_blank">613055</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Atrial fibrillation is the most common sustained cardiac rhythm disturbance, affecting more than 2 million Americans, with an overall prevalence of 0.89%. The prevalence increases rapidly with age, to 2.3% between the ages of 40 and 60 years, and to 5.9% over the age of 65. The most dreaded complication is thromboembolic stroke (Brugada et al., 1997). For a discussion of genetic heterogeneity of atrial fibrillation, see 608583. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_445"><div><strong>Atrial fibrillation</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>445</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0004238</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An atrial arrhythmia characterized by disorganized atrial activity without discrete P waves on the surface EKG, but instead by an undulating baseline or more sharply circumscribed atrial deflections of varying amplitude an frequency ranging from 350 to 600 per minute.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/445">Feature record</a> | <a href="/medgen?term=%22Atrial%20fibrillation%22%5BClinical%20Features%5D%20OR%20445%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite"><ul><li><span class="TLline">Abnormality of the cardiovascular system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_445" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Atrial fibrillation</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38532020">Contemporary pharmacological treatment and management of heart failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bozkurt B</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Cardiol</span>
|
||
2024 Aug;21(8):545-555.
|
||
Epub 2024 Mar 26
|
||
doi: 10.1038/s41569-024-00997-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38532020" target="_blank">38532020</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35093388">Beta-blockers for the treatment of arrhythmias: Bisoprolol - a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Muresan L,
|
||
Cismaru G,
|
||
Muresan C,
|
||
Rosu R,
|
||
Gusetu G,
|
||
Puiu M,
|
||
Mada RO,
|
||
Martins RP</span><br />
|
||
<span class="medgenPMjournal">Ann Pharm Fr</span>
|
||
2022 Sep;80(5):617-634.
|
||
Epub 2022 Jan 31
|
||
doi: 10.1016/j.pharma.2022.01.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35093388" target="_blank">35093388</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30879339">2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Arnett DK,
|
||
Blumenthal RS,
|
||
Albert MA,
|
||
Buroker AB,
|
||
Goldberger ZD,
|
||
Hahn EJ,
|
||
Himmelfarb CD,
|
||
Khera A,
|
||
Lloyd-Jones D,
|
||
McEvoy JW,
|
||
Michos ED,
|
||
Miedema MD,
|
||
Muñoz D,
|
||
Smith SC Jr,
|
||
Virani SS,
|
||
Williams KA Sr,
|
||
Yeboah J,
|
||
Ziaeian B</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2019 Sep 10;140(11):e563-e595.
|
||
Epub 2019 Mar 17
|
||
doi: 10.1161/CIR.0000000000000677.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30879339" target="_blank">30879339</a><a href="/pmc/articles/PMC8351755" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(atrial%20fibrillation%2C%20familial%2C%208)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1156)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng196" target="_blank">UK NICE Guideline NG196, Atrial fibrillation: diagnosis and management, 2021</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37494795">Associations of Life's Essential 8 and fine particulate matter pollution with the incidence of atrial fibrillation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang J,
|
||
Chen G,
|
||
Xia H,
|
||
Wang X,
|
||
Wang C,
|
||
Cai M,
|
||
Gao Y,
|
||
Lip GYH,
|
||
Lin H</span><br />
|
||
<span class="medgenPMjournal">J Hazard Mater</span>
|
||
2023 Oct 5;459:132114.
|
||
Epub 2023 Jul 22
|
||
doi: 10.1016/j.jhazmat.2023.132114.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37494795" target="_blank">37494795</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36179758">Artificial intelligence-guided screening for atrial fibrillation using electrocardiogram during sinus rhythm: a prospective non-randomised interventional trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Noseworthy PA,
|
||
Attia ZI,
|
||
Behnken EM,
|
||
Giblon RE,
|
||
Bews KA,
|
||
Liu S,
|
||
Gosse TA,
|
||
Linn ZD,
|
||
Deng Y,
|
||
Yin J,
|
||
Gersh BJ,
|
||
Graff-Radford J,
|
||
Rabinstein AA,
|
||
Siontis KC,
|
||
Friedman PA,
|
||
Yao X</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2022 Oct 8;400(10359):1206-1212.
|
||
Epub 2022 Sep 27
|
||
doi: 10.1016/S0140-6736(22)01637-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36179758" target="_blank">36179758</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30071583">Potential Impact of Oral Inflammations on Cardiac Functions and Atrial Fibrillation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aarabi G,
|
||
Schnabel RB,
|
||
Heydecke G,
|
||
Seedorf U</span><br />
|
||
<span class="medgenPMjournal">Biomolecules</span>
|
||
2018 Aug 1;8(3)
|
||
doi: 10.3390/biom8030066.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30071583" target="_blank">30071583</a><a href="/pmc/articles/PMC6164509" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28822529">Atrial fibrillation and hyperthyroidism: A literature review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reddy V,
|
||
Taha W,
|
||
Kundumadam S,
|
||
Khan M</span><br />
|
||
<span class="medgenPMjournal">Indian Heart J</span>
|
||
2017 Jul-Aug;69(4):545-550.
|
||
Epub 2017 Jul 5
|
||
doi: 10.1016/j.ihj.2017.07.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28822529" target="_blank">28822529</a><a href="/pmc/articles/PMC5560908" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25496544">The left atrial appendage: anatomy, function, and noninvasive evaluation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Beigel R,
|
||
Wunderlich NC,
|
||
Ho SY,
|
||
Arsanjani R,
|
||
Siegel RJ</span><br />
|
||
<span class="medgenPMjournal">JACC Cardiovasc Imaging</span>
|
||
2014 Dec;7(12):1251-65.
|
||
doi: 10.1016/j.jcmg.2014.08.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25496544" target="_blank">25496544</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Atrial%20fibrillation%2C%20familial%2C%208%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (18650)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39084712">Top stories: Atrial fibrillation diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Marcus GM,
|
||
Noubiap JJ</span><br />
|
||
<span class="medgenPMjournal">Heart Rhythm</span>
|
||
2024 Aug;21(8):1452-1453.
|
||
doi: 10.1016/j.hrthm.2024.06.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39084712" target="_blank">39084712</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36179758">Artificial intelligence-guided screening for atrial fibrillation using electrocardiogram during sinus rhythm: a prospective non-randomised interventional trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Noseworthy PA,
|
||
Attia ZI,
|
||
Behnken EM,
|
||
Giblon RE,
|
||
Bews KA,
|
||
Liu S,
|
||
Gosse TA,
|
||
Linn ZD,
|
||
Deng Y,
|
||
Yin J,
|
||
Gersh BJ,
|
||
Graff-Radford J,
|
||
Rabinstein AA,
|
||
Siontis KC,
|
||
Friedman PA,
|
||
Yao X</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2022 Oct 8;400(10359):1206-1212.
|
||
Epub 2022 Sep 27
|
||
doi: 10.1016/S0140-6736(22)01637-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36179758" target="_blank">36179758</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35393446">Atrial fibrillation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brundel BJJM,
|
||
Ai X,
|
||
Hills MT,
|
||
Kuipers MF,
|
||
Lip GYH,
|
||
de Groot NMS</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Dis Primers</span>
|
||
2022 Apr 7;8(1):21.
|
||
doi: 10.1038/s41572-022-00347-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35393446" target="_blank">35393446</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28822529">Atrial fibrillation and hyperthyroidism: A literature review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reddy V,
|
||
Taha W,
|
||
Kundumadam S,
|
||
Khan M</span><br />
|
||
<span class="medgenPMjournal">Indian Heart J</span>
|
||
2017 Jul-Aug;69(4):545-550.
|
||
Epub 2017 Jul 5
|
||
doi: 10.1016/j.ihj.2017.07.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28822529" target="_blank">28822529</a><a href="/pmc/articles/PMC5560908" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25496544">The left atrial appendage: anatomy, function, and noninvasive evaluation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Beigel R,
|
||
Wunderlich NC,
|
||
Ho SY,
|
||
Arsanjani R,
|
||
Siegel RJ</span><br />
|
||
<span class="medgenPMjournal">JACC Cardiovasc Imaging</span>
|
||
2014 Dec;7(12):1251-65.
|
||
doi: 10.1016/j.jcmg.2014.08.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25496544" target="_blank">25496544</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Atrial%20fibrillation%2C%20familial%2C%208%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (10061)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37698564">Atrial Fibrillation Catheter Ablation vs Medical Therapy and Psychological Distress: A Randomized Clinical Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Al-Kaisey AM,
|
||
Parameswaran R,
|
||
Bryant C,
|
||
Anderson RD,
|
||
Hawson J,
|
||
Chieng D,
|
||
Segan L,
|
||
Voskoboinik A,
|
||
Sugumar H,
|
||
Wong GR,
|
||
Finch S,
|
||
Joseph SA,
|
||
McLellan A,
|
||
Ling LH,
|
||
Morton J,
|
||
Sparks P,
|
||
Sanders P,
|
||
Lee G,
|
||
Kistler PM,
|
||
Kalman JM</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2023 Sep 12;330(10):925-933.
|
||
doi: 10.1001/jama.2023.14685.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37698564" target="_blank">37698564</a><a href="/pmc/articles/PMC10498333" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36179758">Artificial intelligence-guided screening for atrial fibrillation using electrocardiogram during sinus rhythm: a prospective non-randomised interventional trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Noseworthy PA,
|
||
Attia ZI,
|
||
Behnken EM,
|
||
Giblon RE,
|
||
Bews KA,
|
||
Liu S,
|
||
Gosse TA,
|
||
Linn ZD,
|
||
Deng Y,
|
||
Yin J,
|
||
Gersh BJ,
|
||
Graff-Radford J,
|
||
Rabinstein AA,
|
||
Siontis KC,
|
||
Friedman PA,
|
||
Yao X</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2022 Oct 8;400(10359):1206-1212.
|
||
Epub 2022 Sep 27
|
||
doi: 10.1016/S0140-6736(22)01637-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36179758" target="_blank">36179758</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30874766">Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Packer DL,
|
||
Mark DB,
|
||
Robb RA,
|
||
Monahan KH,
|
||
Bahnson TD,
|
||
Poole JE,
|
||
Noseworthy PA,
|
||
Rosenberg YD,
|
||
Jeffries N,
|
||
Mitchell LB,
|
||
Flaker GC,
|
||
Pokushalov E,
|
||
Romanov A,
|
||
Bunch TJ,
|
||
Noelker G,
|
||
Ardashev A,
|
||
Revishvili A,
|
||
Wilber DJ,
|
||
Cappato R,
|
||
Kuck KH,
|
||
Hindricks G,
|
||
Davies DW,
|
||
Kowey PR,
|
||
Naccarelli GV,
|
||
Reiffel JA,
|
||
Piccini JP,
|
||
Silverstein AP,
|
||
Al-Khalidi HR,
|
||
Lee KL;
|
||
CABANA Investigators</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2019 Apr 2;321(13):1261-1274.
|
||
doi: 10.1001/jama.2019.0693.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30874766" target="_blank">30874766</a><a href="/pmc/articles/PMC6450284" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30561633">Atrial fibrillation ablation in heart failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Richter S,
|
||
Di Biase L,
|
||
Hindricks G</span><br />
|
||
<span class="medgenPMjournal">Eur Heart J</span>
|
||
2019 Feb 21;40(8):663-671.
|
||
doi: 10.1093/eurheartj/ehy778.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30561633" target="_blank">30561633</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28181684">Exercise-based cardiac rehabilitation for adults with atrial fibrillation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Risom SS,
|
||
Zwisler AD,
|
||
Johansen PP,
|
||
Sibilitz KL,
|
||
Lindschou J,
|
||
Gluud C,
|
||
Taylor RS,
|
||
Svendsen JH,
|
||
Berg SK</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2017 Feb 9;2(2):CD011197.
|
||
doi: 10.1002/14651858.CD011197.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28181684" target="_blank">28181684</a><a href="/pmc/articles/PMC6464537" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Atrial%20fibrillation%2C%20familial%2C%208%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (12343)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37639219">Prevalence and incidence of diastolic dysfunction in atrial fibrillation: clinical implications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Naser JA,
|
||
Lee E,
|
||
Scott CG,
|
||
Kennedy AM,
|
||
Pellikka PA,
|
||
Lin G,
|
||
Pislaru SV,
|
||
Borlaug BA</span><br />
|
||
<span class="medgenPMjournal">Eur Heart J</span>
|
||
2023 Dec 21;44(48):5049-5060.
|
||
doi: 10.1093/eurheartj/ehad592.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37639219" target="_blank">37639219</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37494795">Associations of Life's Essential 8 and fine particulate matter pollution with the incidence of atrial fibrillation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang J,
|
||
Chen G,
|
||
Xia H,
|
||
Wang X,
|
||
Wang C,
|
||
Cai M,
|
||
Gao Y,
|
||
Lip GYH,
|
||
Lin H</span><br />
|
||
<span class="medgenPMjournal">J Hazard Mater</span>
|
||
2023 Oct 5;459:132114.
|
||
Epub 2023 Jul 22
|
||
doi: 10.1016/j.jhazmat.2023.132114.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37494795" target="_blank">37494795</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29019809">Atrial Fibrillation and Central Nervous Complications in Liver Transplanted Hereditary Transthyretin Amyloidosis Patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wange N,
|
||
Anan I,
|
||
Ericzon BG,
|
||
Pennlert J,
|
||
Pilebro B,
|
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<div class="nl"><a target="_blank" href="/pubmed/25960110">50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Schnabel RB,
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<div class="nl"><a target="_blank" href="/pubmed/23453452">Dental scaling and atrial fibrillation: a nationwide cohort study.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Atrial%20fibrillation%2C%20familial%2C%208%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (11328)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38613511">Blood-based cardiometabolic phenotypes in atrial fibrillation and their associated risk: EAST-AFNET 4 biomolecule study.</a></div>
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2024 Jul 2;120(8):855-868.
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<span class="bold">PMID: </span><a href="/pubmed/38613511" target="_blank">38613511</a><a href="/pmc/articles/PMC11218688" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/32641592">Heart Failure in Atrial Fibrillation - An Update on Clinical and Echocardiographic Implications.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Taniguchi N,
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Miyasaka Y,
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Suwa Y,
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2020 Jul 22;84(8):1212-1217.
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<span class="bold">PMID: </span><a href="/pubmed/32641592" target="_blank">32641592</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/31378392">An artificial intelligence-enabled ECG algorithm for the identification of patients with atrial fibrillation during sinus rhythm: a retrospective analysis of outcome prediction.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Attia ZI,
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Noseworthy PA,
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Lopez-Jimenez F,
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Asirvatham SJ,
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Deshmukh AJ,
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Gersh BJ,
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Carter RE,
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Yao X,
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Rabinstein AA,
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2019 Sep 7;394(10201):861-867.
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<span class="bold">PMID: </span><a href="/pubmed/31378392" target="_blank">31378392</a></div>
|
||
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||
<div class="nl"><a target="_blank" href="/pubmed/29019809">Atrial Fibrillation and Central Nervous Complications in Liver Transplanted Hereditary Transthyretin Amyloidosis Patients.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Wange N,
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Wixner J</span><br />
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<span class="medgenPMjournal">Transplantation</span>
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2018 Feb;102(2):e59-e66.
|
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doi: 10.1097/TP.0000000000001975.
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<span class="bold">PMID: </span><a href="/pubmed/29019809" target="_blank">29019809</a><a href="/pmc/articles/PMC5802266" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/25496544">The left atrial appendage: anatomy, function, and noninvasive evaluation.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Beigel R,
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2014 Dec;7(12):1251-65.
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<span class="bold">PMID: </span><a href="/pubmed/25496544" target="_blank">25496544</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Atrial%20fibrillation%2C%20familial%2C%208%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (12216)</a></div></div>
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||
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<div class="nl"><a target="_blank" href="/pubmed/36006608">A systematic review of the efficacy and safety of anticoagulants in advanced chronic kidney disease.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Parker K,
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Hartemink J,
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Saha A,
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Mitra R,
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2022 Nov;35(8):2015-2033.
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Epub 2022 Aug 25
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doi: 10.1007/s40620-022-01413-x.
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<span class="bold">PMID: </span><a href="/pubmed/36006608" target="_blank">36006608</a><a href="/pmc/articles/PMC9584987" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/35787150">Colchicine for cardiovascular medicine: a systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Casula M,
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Andreis A,
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Avondo S,
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Vaira MP,
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Imazio M</span><br />
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<span class="medgenPMjournal">Future Cardiol</span>
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2022 Aug;18(8):647-659.
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Epub 2022 Jul 5
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||
doi: 10.2217/fca-2020-0206.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35787150" target="_blank">35787150</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/35716859">Cardioneuroablation for vasovagal syncope: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vandenberk B,
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Lei LY,
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Ballantyne B,
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Vickers D,
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Liang Z,
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Sheldon RS,
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Aksu T,
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<span class="medgenPMjournal">Heart Rhythm</span>
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||
2022 Nov;19(11):1804-1812.
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||
Epub 2022 Jun 16
|
||
doi: 10.1016/j.hrthm.2022.06.017.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35716859" target="_blank">35716859</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35093388">Beta-blockers for the treatment of arrhythmias: Bisoprolol - a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Muresan L,
|
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Cismaru G,
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Muresan C,
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Rosu R,
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Gusetu G,
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Puiu M,
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<span class="medgenPMjournal">Ann Pharm Fr</span>
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2022 Sep;80(5):617-634.
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Epub 2022 Jan 31
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<span class="bold">PMID: </span><a href="/pubmed/35093388" target="_blank">35093388</a></div>
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||
<div class="nl"><a target="_blank" href="/pubmed/29061566">Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Baumgartner C,
|
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da Costa BR,
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Collet TH,
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Feller M,
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Ceresini G,
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Peeters RP,
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Luben R,
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Dörr M,
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Walsh JP,
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Bremner A,
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Iacoviello M,
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Macfarlane P,
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Heeringa J,
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Stott DJ,
|
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Westendorp RGJ,
|
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Khaw KT,
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Magnani JW,
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Aujesky D,
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Rodondi N;
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Thyroid Studies Collaboration</span><br />
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<span class="medgenPMjournal">Circulation</span>
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||
2017 Nov 28;136(22):2100-2116.
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||
Epub 2017 Oct 23
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||
doi: 10.1161/CIRCULATIONAHA.117.028753.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29061566" target="_blank">29061566</a><a href="/pmc/articles/PMC5705446" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Atrial%20fibrillation%2C%20familial%2C%208%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (635)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C2751607%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (1)</a></li>
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<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=104155" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=463[geneid]" target="_blank">View ZFHX3 variations in ClinVar</a></li><li><a href="/nuccore/261598996" target="_blank">RefSeqGene</a></li><li><a href="https://catalog.coriell.org/Search?q=613055" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
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