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<meta name="keywords" content="C1838332, disease or syndrome, h. pylori infection, susceptibility to, helicobacter pylori infection, susceptibility to, ifngr1, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Helicobacter pylori is a microaerophilic, gram-negative bacterium that colonizes the gastric mucosa of approximately 50% of the world's population, and is a primary pathogenic factor in benign and malignant gastroduodenal disease (Warren and Marshall, 1983; Blaser and Parsonnet, 1994). Tomb et al. (1997) reported the complete sequence of the circular genome of H. pylori. The 1,667,867-bp genome contains 1,590 predicted coding sequences (genes). Sequence analysis of these genes indicated that the organism has systems for motility, for scavenging iron, and for DNA restriction and modification. Its survival in acid conditions depends, in part, on its ability to establish a positive inside-membrane potential in low pH." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=325004
|
||
ConceptID=C1838332
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Helicobacter pylori infection, susceptibility to</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>325004</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1838332</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>HELICOBACTER PYLORI INFECTION, SUSCEPTIBILITY TO</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="IFNGR1 - ID: 3459 - NCBI Gene" href="/gene/3459" class="medgenPMinfo">IFNGR1</a> (6q23.3)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0010853" target="_blank">MONDO:0010853</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/600263" target="_blank">600263</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Helicobacter pylori is a microaerophilic, gram-negative bacterium that colonizes the gastric mucosa of approximately 50% of the world's population, and is a primary pathogenic factor in benign and malignant gastroduodenal disease (Warren and Marshall, 1983; Blaser and Parsonnet, 1994). Tomb et al. (1997) reported the complete sequence of the circular genome of H. pylori. The 1,667,867-bp genome contains 1,590 predicted coding sequences (genes). Sequence analysis of these genes indicated that the organism has systems for motility, for scavenging iron, and for DNA restriction and modification. Its survival in acid conditions depends, in part, on its ability to establish a positive inside-membrane potential in low pH. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_208857"><div><strong>Helicobacter pylori infection</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>208857</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0850666</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A recurrent infection of the GI tract with helicobacter pylori, a gram-negative, microaerophilic bacterium usually found in the stomach.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/208857">Feature record</a> | <a href="/medgen?term=%22Helicobacter%20pylori%20infection%22%5BClinical%20Features%5D%20OR%20208857%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite"><ul><li><span class="TLline">Abnormality of the digestive system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_208857" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Helicobacter pylori infection</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38414319">Revolution of Helicobacter pylori treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yamaoka Y</span><br />
|
||
<span class="medgenPMjournal">J Gastroenterol Hepatol</span>
|
||
2024 Jun;39(6):1016-1026.
|
||
Epub 2024 Feb 27
|
||
doi: 10.1111/jgh.16526.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38414319" target="_blank">38414319</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37806461">Evolving Concepts in Helicobacter pylori Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moss SF,
|
||
Shah SC,
|
||
Tan MC,
|
||
El-Serag HB</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2024 Feb;166(2):267-283.
|
||
Epub 2023 Oct 6
|
||
doi: 10.1053/j.gastro.2023.09.047.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37806461" target="_blank">37806461</a><a href="/pmc/articles/PMC10843279" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28541262">Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents (Update 2016).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jones NL,
|
||
Koletzko S,
|
||
Goodman K,
|
||
Bontems P,
|
||
Cadranel S,
|
||
Casswall T,
|
||
Czinn S,
|
||
Gold BD,
|
||
Guarner J,
|
||
Elitsur Y,
|
||
Homan M,
|
||
Kalach N,
|
||
Kori M,
|
||
Madrazo A,
|
||
Megraud F,
|
||
Papadopoulou A,
|
||
Rowland M;
|
||
ESPGHAN, NASPGHAN</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Gastroenterol Nutr</span>
|
||
2017 Jun;64(6):991-1003.
|
||
doi: 10.1097/MPG.0000000000001594.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28541262" target="_blank">28541262</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(helicobacter%20pylori%20infection%2C%20susceptibility%20to)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (233)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/cg184" target="_blank">UK NICE Clinical Guideline CG184, Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management, 2019</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39148213">Updated joint ESPGHAN/NASPGHAN guidelines for management of Helicobacter pylori infection in children and adolescents (2023).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Homan M,
|
||
Jones NL,
|
||
Bontems P,
|
||
Carroll MW,
|
||
Czinn SJ,
|
||
Gold BD,
|
||
Goodman K,
|
||
Harris PR,
|
||
Jerris R,
|
||
Kalach N,
|
||
Kori M,
|
||
Megraud F,
|
||
Rowland M,
|
||
Tavares M;
|
||
on behalf of ESPGHAN/NASPGHAN</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Gastroenterol Nutr</span>
|
||
2024 Sep;79(3):758-785.
|
||
Epub 2024 Aug 15
|
||
doi: 10.1002/jpn3.12314.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39148213" target="_blank">39148213</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37806461">Evolving Concepts in Helicobacter pylori Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moss SF,
|
||
Shah SC,
|
||
Tan MC,
|
||
El-Serag HB</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2024 Feb;166(2):267-283.
|
||
Epub 2023 Oct 6
|
||
doi: 10.1053/j.gastro.2023.09.047.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37806461" target="_blank">37806461</a><a href="/pmc/articles/PMC10843279" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36988593">Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Usui Y,
|
||
Taniyama Y,
|
||
Endo M,
|
||
Koyanagi YN,
|
||
Kasugai Y,
|
||
Oze I,
|
||
Ito H,
|
||
Imoto I,
|
||
Tanaka T,
|
||
Tajika M,
|
||
Niwa Y,
|
||
Iwasaki Y,
|
||
Aoi T,
|
||
Hakozaki N,
|
||
Takata S,
|
||
Suzuki K,
|
||
Terao C,
|
||
Hatakeyama M,
|
||
Hirata M,
|
||
Sugano K,
|
||
Yoshida T,
|
||
Kamatani Y,
|
||
Nakagawa H,
|
||
Matsuda K,
|
||
Murakami Y,
|
||
Spurdle AB,
|
||
Matsuo K,
|
||
Momozawa Y</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2023 Mar 30;388(13):1181-1190.
|
||
doi: 10.1056/NEJMoa2211807.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36988593" target="_blank">36988593</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28891138">Epidemiology of Helicobacter pylori infection.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Burucoa C,
|
||
Axon A</span><br />
|
||
<span class="medgenPMjournal">Helicobacter</span>
|
||
2017 Sep;22 Suppl 1
|
||
doi: 10.1111/hel.12403.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28891138" target="_blank">28891138</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28541262">Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents (Update 2016).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jones NL,
|
||
Koletzko S,
|
||
Goodman K,
|
||
Bontems P,
|
||
Cadranel S,
|
||
Casswall T,
|
||
Czinn S,
|
||
Gold BD,
|
||
Guarner J,
|
||
Elitsur Y,
|
||
Homan M,
|
||
Kalach N,
|
||
Kori M,
|
||
Madrazo A,
|
||
Megraud F,
|
||
Papadopoulou A,
|
||
Rowland M;
|
||
ESPGHAN, NASPGHAN</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Gastroenterol Nutr</span>
|
||
2017 Jun;64(6):991-1003.
|
||
doi: 10.1097/MPG.0000000000001594.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28541262" target="_blank">28541262</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Helicobacter%20pylori%20infection%2C%20susceptibility%20to%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1348)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39148213">Updated joint ESPGHAN/NASPGHAN guidelines for management of Helicobacter pylori infection in children and adolescents (2023).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Homan M,
|
||
Jones NL,
|
||
Bontems P,
|
||
Carroll MW,
|
||
Czinn SJ,
|
||
Gold BD,
|
||
Goodman K,
|
||
Harris PR,
|
||
Jerris R,
|
||
Kalach N,
|
||
Kori M,
|
||
Megraud F,
|
||
Rowland M,
|
||
Tavares M;
|
||
on behalf of ESPGHAN/NASPGHAN</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Gastroenterol Nutr</span>
|
||
2024 Sep;79(3):758-785.
|
||
Epub 2024 Aug 15
|
||
doi: 10.1002/jpn3.12314.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39148213" target="_blank">39148213</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38193664">Testing for Helicobacter pylori in an era of antimicrobial resistance.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schuetz AN,
|
||
Theel ES,
|
||
Cole NC,
|
||
Rothstein TE,
|
||
Gordy GG,
|
||
Patel R</span><br />
|
||
<span class="medgenPMjournal">J Clin Microbiol</span>
|
||
2024 Feb 14;62(2):e0073223.
|
||
Epub 2024 Jan 9
|
||
doi: 10.1128/jcm.00732-23.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38193664" target="_blank">38193664</a><a href="/pmc/articles/PMC10865822" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37806461">Evolving Concepts in Helicobacter pylori Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moss SF,
|
||
Shah SC,
|
||
Tan MC,
|
||
El-Serag HB</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2024 Feb;166(2):267-283.
|
||
Epub 2023 Oct 6
|
||
doi: 10.1053/j.gastro.2023.09.047.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37806461" target="_blank">37806461</a><a href="/pmc/articles/PMC10843279" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28541262">Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents (Update 2016).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jones NL,
|
||
Koletzko S,
|
||
Goodman K,
|
||
Bontems P,
|
||
Cadranel S,
|
||
Casswall T,
|
||
Czinn S,
|
||
Gold BD,
|
||
Guarner J,
|
||
Elitsur Y,
|
||
Homan M,
|
||
Kalach N,
|
||
Kori M,
|
||
Madrazo A,
|
||
Megraud F,
|
||
Papadopoulou A,
|
||
Rowland M;
|
||
ESPGHAN, NASPGHAN</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Gastroenterol Nutr</span>
|
||
2017 Jun;64(6):991-1003.
|
||
doi: 10.1097/MPG.0000000000001594.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28541262" target="_blank">28541262</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25278682">Diagnosis of Helicobacter pylori: what should be the gold standard?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Patel SK,
|
||
Pratap CB,
|
||
Jain AK,
|
||
Gulati AK,
|
||
Nath G</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
||
2014 Sep 28;20(36):12847-59.
|
||
doi: 10.3748/wjg.v20.i36.12847.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25278682" target="_blank">25278682</a><a href="/pmc/articles/PMC4177467" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Helicobacter%20pylori%20infection%2C%20susceptibility%20to%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (689)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39148213">Updated joint ESPGHAN/NASPGHAN guidelines for management of Helicobacter pylori infection in children and adolescents (2023).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Homan M,
|
||
Jones NL,
|
||
Bontems P,
|
||
Carroll MW,
|
||
Czinn SJ,
|
||
Gold BD,
|
||
Goodman K,
|
||
Harris PR,
|
||
Jerris R,
|
||
Kalach N,
|
||
Kori M,
|
||
Megraud F,
|
||
Rowland M,
|
||
Tavares M;
|
||
on behalf of ESPGHAN/NASPGHAN</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Gastroenterol Nutr</span>
|
||
2024 Sep;79(3):758-785.
|
||
Epub 2024 Aug 15
|
||
doi: 10.1002/jpn3.12314.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39148213" target="_blank">39148213</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38414319">Revolution of Helicobacter pylori treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yamaoka Y</span><br />
|
||
<span class="medgenPMjournal">J Gastroenterol Hepatol</span>
|
||
2024 Jun;39(6):1016-1026.
|
||
Epub 2024 Feb 27
|
||
doi: 10.1111/jgh.16526.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38414319" target="_blank">38414319</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37806461">Evolving Concepts in Helicobacter pylori Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moss SF,
|
||
Shah SC,
|
||
Tan MC,
|
||
El-Serag HB</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2024 Feb;166(2):267-283.
|
||
Epub 2023 Oct 6
|
||
doi: 10.1053/j.gastro.2023.09.047.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37806461" target="_blank">37806461</a><a href="/pmc/articles/PMC10843279" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28541262">Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents (Update 2016).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jones NL,
|
||
Koletzko S,
|
||
Goodman K,
|
||
Bontems P,
|
||
Cadranel S,
|
||
Casswall T,
|
||
Czinn S,
|
||
Gold BD,
|
||
Guarner J,
|
||
Elitsur Y,
|
||
Homan M,
|
||
Kalach N,
|
||
Kori M,
|
||
Madrazo A,
|
||
Megraud F,
|
||
Papadopoulou A,
|
||
Rowland M;
|
||
ESPGHAN, NASPGHAN</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Gastroenterol Nutr</span>
|
||
2017 Jun;64(6):991-1003.
|
||
doi: 10.1097/MPG.0000000000001594.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28541262" target="_blank">28541262</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28529929">Novel and Effective Therapeutic Regimens for Helicobacter pylori in an Era of Increasing Antibiotic Resistance.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hu Y,
|
||
Zhu Y,
|
||
Lu NH</span><br />
|
||
<span class="medgenPMjournal">Front Cell Infect Microbiol</span>
|
||
2017;7:168.
|
||
Epub 2017 May 5
|
||
doi: 10.3389/fcimb.2017.00168.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28529929" target="_blank">28529929</a><a href="/pmc/articles/PMC5418237" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Helicobacter%20pylori%20infection%2C%20susceptibility%20to%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (909)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37105073">Patient-derived organoid culture of gastric cancer for disease modeling and drug sensitivity testing.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zu M,
|
||
Hao X,
|
||
Ning J,
|
||
Zhou X,
|
||
Gong Y,
|
||
Lang Y,
|
||
Xu W,
|
||
Zhang J,
|
||
Ding S</span><br />
|
||
<span class="medgenPMjournal">Biomed Pharmacother</span>
|
||
2023 Jul;163:114751.
|
||
Epub 2023 Apr 26
|
||
doi: 10.1016/j.biopha.2023.114751.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37105073" target="_blank">37105073</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31484488">Epidemiology of gallbladder cancer in India.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dutta U,
|
||
Bush N,
|
||
Kalsi D,
|
||
Popli P,
|
||
Kapoor VK</span><br />
|
||
<span class="medgenPMjournal">Chin Clin Oncol</span>
|
||
2019 Aug;8(4):33.
|
||
doi: 10.21037/cco.2019.08.03.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31484488" target="_blank">31484488</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31433314">Treatment of Helicobacter pylori.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Argueta EA,
|
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Moss SF</span><br />
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<span class="medgenPMjournal">Curr Opin Gastroenterol</span>
|
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2019 Nov;35(6):544-550.
|
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doi: 10.1097/MOG.0000000000000578.
|
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<span class="bold">PMID: </span><a href="/pubmed/31433314" target="_blank">31433314</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25469011">Causes and consequences of microsatellite instability in gastric carcinogenesis.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Velho S,
|
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Fernandes MS,
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Leite M,
|
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Figueiredo C,
|
||
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|
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<span class="medgenPMjournal">World J Gastroenterol</span>
|
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2014 Nov 28;20(44):16433-42.
|
||
doi: 10.3748/wjg.v20.i44.16433.
|
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<span class="bold">PMID: </span><a href="/pubmed/25469011" target="_blank">25469011</a><a href="/pmc/articles/PMC4248186" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25278682">Diagnosis of Helicobacter pylori: what should be the gold standard?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Patel SK,
|
||
Pratap CB,
|
||
Jain AK,
|
||
Gulati AK,
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||
Nath G</span><br />
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<span class="medgenPMjournal">World J Gastroenterol</span>
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2014 Sep 28;20(36):12847-59.
|
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doi: 10.3748/wjg.v20.i36.12847.
|
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<span class="bold">PMID: </span><a href="/pubmed/25278682" target="_blank">25278682</a><a href="/pmc/articles/PMC4177467" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Helicobacter%20pylori%20infection%2C%20susceptibility%20to%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (406)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/38809553">Helicobacter pylori Treatment and Gastric Cancer Risk Among Individuals With High Genetic Risk for Gastric Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Xu HM,
|
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Han Y,
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Liu ZC,
|
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Yin ZY,
|
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Wang MY,
|
||
Yu C,
|
||
Ma JL,
|
||
Sun D,
|
||
Liu WD,
|
||
Zhang Y,
|
||
Zhou T,
|
||
Zhang JY,
|
||
Pei P,
|
||
Yang L,
|
||
Millwood IY,
|
||
Walters RG,
|
||
Chen Y,
|
||
Du H,
|
||
Chen Z,
|
||
You WC,
|
||
Li L,
|
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Pan KF,
|
||
Lv J,
|
||
Li WQ</span><br />
|
||
<span class="medgenPMjournal">JAMA Netw Open</span>
|
||
2024 May 1;7(5):e2413708.
|
||
doi: 10.1001/jamanetworkopen.2024.13708.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38809553" target="_blank">38809553</a><a href="/pmc/articles/PMC11137637" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33692136">Helicobacter pylori Antimicrobial Resistance and Gene Variants in High- and Low-Gastric-Cancer-Risk Populations.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mannion A,
|
||
Dzink-Fox J,
|
||
Shen Z,
|
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Piazuelo MB,
|
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Wilson KT,
|
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Correa P,
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Peek RM Jr,
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Camargo MC,
|
||
Fox JG</span><br />
|
||
<span class="medgenPMjournal">J Clin Microbiol</span>
|
||
2021 Apr 20;59(5)
|
||
doi: 10.1128/JCM.03203-20.
|
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<span class="bold">PMID: </span><a href="/pubmed/33692136" target="_blank">33692136</a><a href="/pmc/articles/PMC8091839" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29990487">Prevalence of Antibiotic Resistance in Helicobacter pylori: A Systematic Review and Meta-analysis in World Health Organization Regions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Savoldi A,
|
||
Carrara E,
|
||
Graham DY,
|
||
Conti M,
|
||
Tacconelli E</span><br />
|
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<span class="medgenPMjournal">Gastroenterology</span>
|
||
2018 Nov;155(5):1372-1382.e17.
|
||
Epub 2018 Jul 7
|
||
doi: 10.1053/j.gastro.2018.07.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29990487" target="_blank">29990487</a><a href="/pmc/articles/PMC6905086" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28529929">Novel and Effective Therapeutic Regimens for Helicobacter pylori in an Era of Increasing Antibiotic Resistance.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hu Y,
|
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Zhu Y,
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Lu NH</span><br />
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<span class="medgenPMjournal">Front Cell Infect Microbiol</span>
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2017;7:168.
|
||
Epub 2017 May 5
|
||
doi: 10.3389/fcimb.2017.00168.
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<span class="bold">PMID: </span><a href="/pubmed/28529929" target="_blank">28529929</a><a href="/pmc/articles/PMC5418237" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25278682">Diagnosis of Helicobacter pylori: what should be the gold standard?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Patel SK,
|
||
Pratap CB,
|
||
Jain AK,
|
||
Gulati AK,
|
||
Nath G</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
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2014 Sep 28;20(36):12847-59.
|
||
doi: 10.3748/wjg.v20.i36.12847.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25278682" target="_blank">25278682</a><a href="/pmc/articles/PMC4177467" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Helicobacter%20pylori%20infection%2C%20susceptibility%20to%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (634)</a></div></div>
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|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/36687120">Third-line and rescue therapy for refractory Helicobacter pylori infection: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Moraes Andrade PV,
|
||
Monteiro YM,
|
||
Chehter EZ</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
||
2023 Jan 14;29(2):390-409.
|
||
doi: 10.3748/wjg.v29.i2.390.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36687120" target="_blank">36687120</a><a href="/pmc/articles/PMC9846933" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35410853">Helicobacter pylori Infection and Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Heydari K,
|
||
Yousefi M,
|
||
Alizadeh-Navaei R,
|
||
Lotfi P,
|
||
Sheydaee F,
|
||
Raei M,
|
||
Vahdatinia A,
|
||
Hessami A,
|
||
Rafati S,
|
||
Moosazadeh M,
|
||
Ghasemian R,
|
||
Salehi F,
|
||
Massoudi H,
|
||
Ghaffari-Saravi F,
|
||
Rismantab S</span><br />
|
||
<span class="medgenPMjournal">Turk J Gastroenterol</span>
|
||
2022 Mar;33(3):171-181.
|
||
doi: 10.5152/tjg.2022.21467.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35410853" target="_blank">35410853</a><a href="/pmc/articles/PMC9128487" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31368293">Helicobacter pylori infection and the risk of colorectal carcinoma: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yang F,
|
||
Xu YL,
|
||
Zhu RF</span><br />
|
||
<span class="medgenPMjournal">Minerva Med</span>
|
||
2019 Oct;110(5):464-470.
|
||
doi: 10.23736/S0026-4806.19.05942-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31368293" target="_blank">31368293</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29990487">Prevalence of Antibiotic Resistance in Helicobacter pylori: A Systematic Review and Meta-analysis in World Health Organization Regions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Savoldi A,
|
||
Carrara E,
|
||
Graham DY,
|
||
Conti M,
|
||
Tacconelli E</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2018 Nov;155(5):1372-1382.e17.
|
||
Epub 2018 Jul 7
|
||
doi: 10.1053/j.gastro.2018.07.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29990487" target="_blank">29990487</a><a href="/pmc/articles/PMC6905086" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28541262">Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents (Update 2016).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jones NL,
|
||
Koletzko S,
|
||
Goodman K,
|
||
Bontems P,
|
||
Cadranel S,
|
||
Casswall T,
|
||
Czinn S,
|
||
Gold BD,
|
||
Guarner J,
|
||
Elitsur Y,
|
||
Homan M,
|
||
Kalach N,
|
||
Kori M,
|
||
Madrazo A,
|
||
Megraud F,
|
||
Papadopoulou A,
|
||
Rowland M;
|
||
ESPGHAN, NASPGHAN</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Gastroenterol Nutr</span>
|
||
2017 Jun;64(6):991-1003.
|
||
doi: 10.1097/MPG.0000000000001594.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28541262" target="_blank">28541262</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Helicobacter%20pylori%20infection%2C%20susceptibility%20to%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (51)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C1838332%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (8)</a></li>
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<li><a href="/gtr/tests?term=C1838332%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (9)</a></li>
|
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<li><a href="/gtr/tests?term=C1838332%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (2)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C1838332%5bDISCUI%5d" target="_blank">See all (11)</a></total></li>
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