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<meta name="keywords" content="C1522135, finding, high blood magnesium levels, high blood mg levels, hypermagnesemia, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="An abnormally increased magnesium concentration in the blood." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=312005
ConceptID=C1522135
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Hypermagnesemia</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>312005</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C1522135</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>High blood magnesium levels; High blood Mg levels</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0002918">HP:0002918</a></td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">An abnormally increased magnesium concentration in the blood. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1522135[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=312005">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=312005" ref="ncbi_uid=312005">V</a></span></span><span class="TLline">Hypermagnesemia</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/233128" ref="tree=MeSH" title="MedGen record for Abnormal Blood Chemistry and Hematology Test Result">Abnormal Blood Chemistry and Hematology Test Result</a></span><ul><li><span class="matched_ds">Hypermagnesemia</span></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_137973"><div><strong>Familial hypocalciuric hypercalcemia 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>137973</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0342637</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Familial hypocalciuric hypercalcemia (HHC) is a heritable disorder of mineral homeostasis that is transmitted as an autosomal dominant trait with a high degree of penetrance. HHC is characterized biochemically by lifelong elevation of serum calcium concentrations and is associated with inappropriately low urinary calcium excretion and a normal or mildly elevated circulating parathyroid hormone (PTH; 168450) level. Hypermagnesemia is typically present. Individuals with HHC are usually asymptomatic and the disorder is considered benign. However, chondrocalcinosis and pancreatitis occur in some adults (summary by Hannan et al., 2010).&#13; Characteristic features of familial hypocalciuric hypercalcemia include mild to moderate hypercalcemia, nonsuppressed parathyroid hormone, relative hypocalciuria while hypercalcemic (calcium/creatinine clearance ratio less than 0.01, or 24-hr urine calcium less than 6.25 mmol), almost 100% penetrance of hypercalcemia from birth, absence of complications, persistence of hypercalcemia following subtotal parathyroidectomy, and normal parathyroid size, weight, and histology at surgery. However, atypical presentations with severe hypercalcemia, hypercalciuria with or without nephrolithiasis or nephrocalcinosis, kindreds with affected members displaying either hypercalciuria or hypocalciuria, postoperative normocalcemia, and pancreatitis have all been described in FHH (Warner et al., 2004).&#13; Genetic Heterogeneity of Hypocalciuric Hypercalcemia&#13; Familial hypocalciuric hypercalcemia type II (HHC2; 145981) is caused by mutation in the GNA11 gene (139313) on chromosome 19p13, and HHC3 (600740) is caused by mutation in the AP2S1 gene (602242) on chromosome 19q13.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/137973">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_322173"><div><strong>Familial hypocalciuric hypercalcemia 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>322173</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1833372</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Any familial hypocalciuric hypercalcemia in which the cause of the disease is a mutation in the AP2S1 gene.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/322173">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_374447"><div><strong>Familial hypocalciuric hypercalcemia 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>374447</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1840347</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Familial hypocalciuric hypercalcemia type II (HHC2) is an autosomal dominant disorder characterized by lifelong elevations of serum calcium concentrations with low urinary calcium excretion and normal circulating parathyroid hormone concentrations in most patients. Patients are generally asymptomatic (summary by Nesbit et al., 2013).&#13; For a general phenotypic description and a discussion of genetic heterogeneity of hypocalciuric hypercalcemia, see HHC1 (145980).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/374447">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1621482"><div><strong>HELIX syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1621482</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4522164</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">HELIX syndrome is an autosomal recessive disorder characterized by Hypohidrosis, Electrolyte imbalance, Lacrimal gland dysfunction, Ichthyosis, and Xerostomia (summary by Hadj-Rabia et al., 2018).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1621482">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_137973" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial hypocalciuric hypercalcemia 1</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_374447" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial hypocalciuric hypercalcemia 2</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_322173" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial hypocalciuric hypercalcemia 3</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1621482" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">HELIX syndrome</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/37696258">Current Treatment Practices for Adult Patients with Constipation in Japan.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kessoku T,
Misawa N,
Ohkubo H,
Nakajima A</span><br />
<span class="medgenPMjournal">Digestion</span>
2024;105(1):40-48.
Epub 2023 Sep 11
doi: 10.1159/000533548.
<span class="bold">PMID: </span><a href="/pubmed/37696258" target="_blank">37696258</a><a href="/pmc/articles/PMC10777713" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36241476">The Effects of Magnesium Coadminstration During Treatment of Hypokalemia in the Emergency Department.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tuttle A,
Fitter S,
Hua H,
Moussavi K</span><br />
<span class="medgenPMjournal">J Emerg Med</span>
2022 Sep;63(3):399-413.
Epub 2022 Oct 11
doi: 10.1016/j.jemermed.2022.06.007.
<span class="bold">PMID: </span><a href="/pubmed/36241476" target="_blank">36241476</a></div>
<div class="nl"><a target="_blank" href="/pubmed/16085929">Treatment of electrolyte disorders in adult patients in the intensive care unit.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kraft MD,
Btaiche IF,
Sacks GS,
Kudsk KA</span><br />
<span class="medgenPMjournal">Am J Health Syst Pharm</span>
2005 Aug 15;62(16):1663-82.
doi: 10.2146/ajhp040300.
<span class="bold">PMID: </span><a href="/pubmed/16085929" target="_blank">16085929</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22hypermagnesemia%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (11)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37512002">Hypermagnesemia in Clinical Practice.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Aal-Hamad AH,
Al-Alawi AM,
Kashoub MS,
Falhammar H</span><br />
<span class="medgenPMjournal">Medicina (Kaunas)</span>
2023 Jun 24;59(7)
doi: 10.3390/medicina59071190.
<span class="bold">PMID: </span><a href="/pubmed/37512002" target="_blank">37512002</a><a href="/pmc/articles/PMC10384947" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35076791">The emerging role of magnesium in CKD.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sakaguchi Y</span><br />
<span class="medgenPMjournal">Clin Exp Nephrol</span>
2022 May;26(5):379-384.
Epub 2022 Jan 25
doi: 10.1007/s10157-022-02182-4.
<span class="bold">PMID: </span><a href="/pubmed/35076791" target="_blank">35076791</a><a href="/pmc/articles/PMC9012765" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27906866">Inherited and acquired disorders of magnesium homeostasis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wolf MT</span><br />
<span class="medgenPMjournal">Curr Opin Pediatr</span>
2017 Apr;29(2):187-198.
doi: 10.1097/MOP.0000000000000450.
<span class="bold">PMID: </span><a href="/pubmed/27906866" target="_blank">27906866</a><a href="/pmc/articles/PMC5572672" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26404370">Magnesium in Prevention and Therapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gröber U,
Schmidt J,
Kisters K</span><br />
<span class="medgenPMjournal">Nutrients</span>
2015 Sep 23;7(9):8199-226.
doi: 10.3390/nu7095388.
<span class="bold">PMID: </span><a href="/pubmed/26404370" target="_blank">26404370</a><a href="/pmc/articles/PMC4586582" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26303319">Pathophysiology of Calcium, Phosphorus, and Magnesium Dysregulation in Chronic Kidney Disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Felsenfeld AJ,
Levine BS,
Rodriguez M</span><br />
<span class="medgenPMjournal">Semin Dial</span>
2015 Nov-Dec;28(6):564-77.
Epub 2015 Aug 25
doi: 10.1111/sdi.12411.
<span class="bold">PMID: </span><a href="/pubmed/26303319" target="_blank">26303319</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypermagnesemia%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (180)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/36868730">Physiology of a Forgotten Electrolyte-Magnesium Disorders.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ray E,
Mohan K,
Ahmad S,
Wolf MTF</span><br />
<span class="medgenPMjournal">Adv Kidney Dis Health</span>
2023 Mar;30(2):148-163.
doi: 10.1053/j.akdh.2022.12.001.
<span class="bold">PMID: </span><a href="/pubmed/36868730" target="_blank">36868730</a><a href="/pmc/articles/PMC10291516" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30220246">Hypomagnesemia and hypermagnesemia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Van Laecke S</span><br />
<span class="medgenPMjournal">Acta Clin Belg</span>
2019 Feb;74(1):41-47.
Epub 2018 Sep 17
doi: 10.1080/17843286.2018.1516173.
<span class="bold">PMID: </span><a href="/pubmed/30220246" target="_blank">30220246</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26404370">Magnesium in Prevention and Therapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gröber U,
Schmidt J,
Kisters K</span><br />
<span class="medgenPMjournal">Nutrients</span>
2015 Sep 23;7(9):8199-226.
doi: 10.3390/nu7095388.
<span class="bold">PMID: </span><a href="/pubmed/26404370" target="_blank">26404370</a><a href="/pmc/articles/PMC4586582" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12766548">Hypomagnesemia and hypermagnesemia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Topf JM,
Murray PT</span><br />
<span class="medgenPMjournal">Rev Endocr Metab Disord</span>
2003 May;4(2):195-206.
doi: 10.1023/a:1022950321817.
<span class="bold">PMID: </span><a href="/pubmed/12766548" target="_blank">12766548</a></div>
<div class="nl"><a target="_blank" href="/pubmed/2195859">Magnesium replacement therapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">DiPalma JR</span><br />
<span class="medgenPMjournal">Am Fam Physician</span>
1990 Jul;42(1):173-6.
<span class="bold">PMID: </span><a href="/pubmed/2195859" target="_blank">2195859</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypermagnesemia%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (96)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/38372687">Magnesium Disorders: Core Curriculum 2024.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Adomako EA,
Yu ASL</span><br />
<span class="medgenPMjournal">Am J Kidney Dis</span>
2024 Jun;83(6):803-815.
Epub 2024 Feb 17
doi: 10.1053/j.ajkd.2023.10.017.
<span class="bold">PMID: </span><a href="/pubmed/38372687" target="_blank">38372687</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37512002">Hypermagnesemia in Clinical Practice.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Aal-Hamad AH,
Al-Alawi AM,
Kashoub MS,
Falhammar H</span><br />
<span class="medgenPMjournal">Medicina (Kaunas)</span>
2023 Jun 24;59(7)
doi: 10.3390/medicina59071190.
<span class="bold">PMID: </span><a href="/pubmed/37512002" target="_blank">37512002</a><a href="/pmc/articles/PMC10384947" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33525523">Magnesium Oxide in Constipation.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mori H,
Tack J,
Suzuki H</span><br />
<span class="medgenPMjournal">Nutrients</span>
2021 Jan 28;13(2)
doi: 10.3390/nu13020421.
<span class="bold">PMID: </span><a href="/pubmed/33525523" target="_blank">33525523</a><a href="/pmc/articles/PMC7911806" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26404370">Magnesium in Prevention and Therapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gröber U,
Schmidt J,
Kisters K</span><br />
<span class="medgenPMjournal">Nutrients</span>
2015 Sep 23;7(9):8199-226.
doi: 10.3390/nu7095388.
<span class="bold">PMID: </span><a href="/pubmed/26404370" target="_blank">26404370</a><a href="/pmc/articles/PMC4586582" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/16085929">Treatment of electrolyte disorders in adult patients in the intensive care unit.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kraft MD,
Btaiche IF,
Sacks GS,
Kudsk KA</span><br />
<span class="medgenPMjournal">Am J Health Syst Pharm</span>
2005 Aug 15;62(16):1663-82.
doi: 10.2146/ajhp040300.
<span class="bold">PMID: </span><a href="/pubmed/16085929" target="_blank">16085929</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypermagnesemia%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (202)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/27906866">Inherited and acquired disorders of magnesium homeostasis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wolf MT</span><br />
<span class="medgenPMjournal">Curr Opin Pediatr</span>
2017 Apr;29(2):187-198.
doi: 10.1097/MOP.0000000000000450.
<span class="bold">PMID: </span><a href="/pubmed/27906866" target="_blank">27906866</a><a href="/pmc/articles/PMC5572672" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24766937">Calcium, magnesium, and phosphate abnormalities in the emergency department.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chang WT,
Radin B,
McCurdy MT</span><br />
<span class="medgenPMjournal">Emerg Med Clin North Am</span>
2014 May;32(2):349-66.
Epub 2014 Feb 19
doi: 10.1016/j.emc.2013.12.006.
<span class="bold">PMID: </span><a href="/pubmed/24766937" target="_blank">24766937</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22990036">Calcium administration during cardiac arrest: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kette F,
Ghuman J,
Parr M</span><br />
<span class="medgenPMjournal">Eur J Emerg Med</span>
2013 Apr;20(2):72-8.
doi: 10.1097/MEJ.0b013e328358e336.
<span class="bold">PMID: </span><a href="/pubmed/22990036" target="_blank">22990036</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10661484">Fatal hypermagnesemia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Schelling JR</span><br />
<span class="medgenPMjournal">Clin Nephrol</span>
2000 Jan;53(1):61-5.
<span class="bold">PMID: </span><a href="/pubmed/10661484" target="_blank">10661484</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10726809">Magnesium in disease: a review with special emphasis on the serum ionized magnesium.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sanders GT,
Huijgen HJ,
Sanders R</span><br />
<span class="medgenPMjournal">Clin Chem Lab Med</span>
1999 Nov-Dec;37(11-12):1011-33.
doi: 10.1515/CCLM.1999.151.
<span class="bold">PMID: </span><a href="/pubmed/10726809" target="_blank">10726809</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypermagnesemia%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (99)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/32866952">Continuous Observation of Serum Total Magnesium Level in Patients Undergoing Hemodialysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Yang W,
Wang E,
Chen W,
Chen C,
Chen S</span><br />
<span class="medgenPMjournal">Blood Purif</span>
2021;50(2):196-204.
Epub 2020 Aug 31
doi: 10.1159/000509788.
<span class="bold">PMID: </span><a href="/pubmed/32866952" target="_blank">32866952</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32336169">Magnesium intoxication in women with preeclampsia with severe features treated with magnesium sulfate.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Akbar MIA,
Yoseph D,
- A,
Bachnas MA,
Dachlan EG,
Dekker GA,
Ernawati</span><br />
<span class="medgenPMjournal">Hypertens Pregnancy</span>
2020 Aug;39(3):221-227.
Epub 2020 Apr 25
doi: 10.1080/10641955.2020.1754851.
<span class="bold">PMID: </span><a href="/pubmed/32336169" target="_blank">32336169</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30220246">Hypomagnesemia and hypermagnesemia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Van Laecke S</span><br />
<span class="medgenPMjournal">Acta Clin Belg</span>
2019 Feb;74(1):41-47.
Epub 2018 Sep 17
doi: 10.1080/17843286.2018.1516173.
<span class="bold">PMID: </span><a href="/pubmed/30220246" target="_blank">30220246</a></div>
<div class="nl"><a target="_blank" href="/pubmed/17541217">Electrolyte disturbances in patients with hyponatremia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Liamis G,
Mitrogianni Z,
Liberopoulos EN,
Tsimihodimos V,
Elisaf M</span><br />
<span class="medgenPMjournal">Intern Med</span>
2007;46(11):685-90.
Epub 2007 Jun 1
doi: 10.2169/internalmedicine.46.6223.
<span class="bold">PMID: </span><a href="/pubmed/17541217" target="_blank">17541217</a></div>
<div class="nl"><a target="_blank" href="/pubmed/3985729">Frequency of hypomagnesemia in hospitalized patients receiving digitalis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Whang R,
Oei TO,
Watanabe A</span><br />
<span class="medgenPMjournal">Arch Intern Med</span>
1985 Apr;145(4):655-6.
<span class="bold">PMID: </span><a href="/pubmed/3985729" target="_blank">3985729</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypermagnesemia%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (109)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/34001688">Magnesium Disorders and Prognosis in Heart Failure: A Systematic Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Voultsos P,
Bazmpani MA,
Papanastasiou CA,
Papadopoulos CE,
Efthimiadis G,
Karvounis H,
Kalogeropoulos AP,
Karamitsos TD</span><br />
<span class="medgenPMjournal">Cardiol Rev</span>
2022 Nov-Dec 01;30(6):281-285.
Epub 2021 May 12
doi: 10.1097/CRD.0000000000000397.
<span class="bold">PMID: </span><a href="/pubmed/34001688" target="_blank">34001688</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30888644">Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Xiong J,
He T,
Wang M,
Nie L,
Zhang Y,
Wang Y,
Huang Y,
Feng B,
Zhang J,
Zhao J</span><br />
<span class="medgenPMjournal">J Nephrol</span>
2019 Oct;32(5):791-802.
Epub 2019 Mar 19
doi: 10.1007/s40620-019-00601-6.
<span class="bold">PMID: </span><a href="/pubmed/30888644" target="_blank">30888644</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27977579">The association of serum magnesium and mortality outcomes in heart failure patients: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Angkananard T,
Anothaisintawee T,
Eursiriwan S,
Gorelik O,
McEvoy M,
Attia J,
Thakkinstian A</span><br />
<span class="medgenPMjournal">Medicine (Baltimore)</span>
2016 Dec;95(50):e5406.
doi: 10.1097/MD.0000000000005406.
<span class="bold">PMID: </span><a href="/pubmed/27977579" target="_blank">27977579</a><a href="/pmc/articles/PMC5268025" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27016536">Hypomagnesemia and mortality in patients admitted to intensive care unit: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Upala S,
Jaruvongvanich V,
Wijarnpreecha K,
Sanguankeo A</span><br />
<span class="medgenPMjournal">QJM</span>
2016 Jul;109(7):453-459.
Epub 2016 Mar 24
doi: 10.1093/qjmed/hcw048.
<span class="bold">PMID: </span><a href="/pubmed/27016536" target="_blank">27016536</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22990036">Calcium administration during cardiac arrest: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kette F,
Ghuman J,
Parr M</span><br />
<span class="medgenPMjournal">Eur J Emerg Med</span>
2013 Apr;20(2):72-8.
doi: 10.1097/MEJ.0b013e328358e336.
<span class="bold">PMID: </span><a href="/pubmed/22990036" target="_blank">22990036</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypermagnesemia%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C1522135%5bDISCUI%5d&amp;filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (3)</a></li>
<li><a href="/gtr/tests?term=C1522135%5bDISCUI%5d&amp;filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (3)</a></li>
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