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<meta name="keywords" content="C1140680, akt1, ca - cancer of ovary, cancer of ovary, cancer of the ovary, cancer, ovarian, cancer, ovary, cancers, ovarian, cancers, ovary, cdh1, ctnnb1, erbb2, malignant neoplasm of ovary, malignant neoplasm of the ovary, malignant ovarian neoplasm, malignant ovarian tumor, malignant ovarian tumour, malignant ovary neoplasm, malignant tumor of ovary, malignant tumor of the ovary, malignant tumour of ovary, malignant tumour of the ovary, neoplastic process, opcml, ovarian cancer, ovarian cancer, epithelial, ovarian cancer, somatic, ovarian cancers, ovarian malignant tumor, ovarian malignant tumour, ovary cancer, ovary cancers, pik3ca, primary ovarian cancer, prkn, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases (Chi et al., 2001). These typical features relate to the biology of the disease, which is a principal determinant of outcome (Auersperg et al., 2001). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium (Stany et al., 2008; Soslow, 2008)." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=216027
|
||
ConceptID=C1140680
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Ovarian cancer</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>216027</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1140680</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>OVARIAN CANCER, SOMATIC</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>CA - Cancer of ovary (363443007); Cancer of ovary (363443007); Ovarian cancer (363443007); Malignant tumor of ovary (363443007)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Genes (locations):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="AKT1 - ID: 207 - NCBI Gene" href="/gene/207" class="medgenPMinfo">AKT1</a> (14q32.33); <a target="_blank" title="CDH1 - ID: 999 - NCBI Gene" href="/gene/999" class="medgenPMinfo">CDH1</a> (16q22.1); <a target="_blank" title="CTNNB1 - ID: 1499 - NCBI Gene" href="/gene/1499" class="medgenPMinfo">CTNNB1</a> (3p22.1); <a target="_blank" title="ERBB2 - ID: 2064 - NCBI Gene" href="/gene/2064" class="medgenPMinfo">ERBB2</a> (17q12); <a target="_blank" title="OPCML - ID: 4978 - NCBI Gene" href="/gene/4978" class="medgenPMinfo">OPCML</a> (11q25); <a target="_blank" title="PIK3CA - ID: 5290 - NCBI Gene" href="/gene/5290" class="medgenPMinfo">PIK3CA</a> (3q26.32); <a target="_blank" title="PRKN - ID: 5071 - NCBI Gene" href="/gene/5071" class="medgenPMinfo">PRKN</a> (6q26)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0008170" target="_blank">MONDO:0008170</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/167000" target="_blank">167000</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=213500">ORPHA213500</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases (Chi et al., 2001). These typical features relate to the biology of the disease, which is a principal determinant of outcome (Auersperg et al., 2001). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium (Stany et al., 2008; Soslow, 2008). [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_117">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Additional_description">Additional description</h1><a sid="117" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><div class="mgSection"><strong>From MedlinePlus Genetics</strong><br />Ovarian cancer is a disease that affects women. In this form of cancer, certain cells in the ovary become abnormal and multiply uncontrollably to form a tumor. The ovaries are the female reproductive organs in which egg cells are produced. In about 90 percent of cases, ovarian cancer occurs after age 40, and most cases occur after age 60.<br /><br />The most common form of ovarian cancer begins in epithelial cells, which are the cells that line the surfaces and cavities of the body. These cancers can arise in the epithelial cells on the surface of the ovary. However, researchers suggest that many or even most ovarian cancers begin in epithelial cells on the fringes (fimbriae) at the end of one of the fallopian tubes, and the cancerous cells migrate to the ovary.<br /><br />Cancer can also begin in epithelial cells that form the lining of the abdomen (the peritoneum). This form of cancer, called primary peritoneal cancer, resembles epithelial ovarian cancer in its origin, symptoms, progression, and treatment. Primary peritoneal cancer often spreads to the ovaries. It can also occur even if the ovaries have been removed. Because cancers that begin in the ovaries, fallopian tubes, and peritoneum are so similar and spread easily from one of these structures to the others, they are often difficult to distinguish. These cancers are so closely related that they are generally considered collectively by experts.<br /><br />In about 10 percent of cases, ovarian cancer develops not in epithelial cells but in germ cells, which are precursors to egg cells, or in hormone-producing ovarian cells called granulosa cells.<br /><br />In its early stages, ovarian cancer usually does not cause noticeable symptoms. As the cancer progresses, signs and symptoms can include pain or a feeling of heaviness in the pelvis or lower abdomen, bloating, feeling full quickly when eating, back pain, vaginal bleeding between menstrual periods or after menopause, or changes in urinary or bowel habits. However, these changes can occur as part of many different conditions. Having one or more of these symptoms does not mean that a woman has ovarian cancer.<br /><br />In some cases, cancerous tumors can invade surrounding tissue and spread to other parts of the body. If ovarian cancer spreads, cancerous tumors most often appear in the abdominal cavity or on the surfaces of nearby organs such as the bladder or colon. Tumors that begin at one site and then spread to other areas of the body are called metastatic cancers.<br /><br />Some ovarian cancers cluster in families. These cancers are described as hereditary and are associated with inherited gene mutations. Hereditary ovarian cancers tend to develop earlier in life than non-inherited (sporadic) cases.<br /><br />Because it is often diagnosed at a late stage, ovarian cancer can be difficult to treat; it leads to the deaths of about 14,000 women annually in the United States, more than any other gynecological cancer. However, when it is diagnosed and treated early, the 5-year survival rate is high. <a target="_blank" href="https://medlineplus.gov/genetics/condition/ovarian-cancer">https://medlineplus.gov/genetics/condition/ovarian-cancer</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_41680"><div><strong>Dysgerminoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>41680</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0013377</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The presence of a dysgerminoma, i.e., an undifferentiated germ cell tumor of the ovary.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/41680">Feature record</a> | <a href="/medgen?term=%22Dysgerminoma%22%5BClinical%20Features%5D%20OR%2041680%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_870531"><div><strong>Ovarian papillary adenocarcinoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>870531</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4024979</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The presence of a papillary adenocarcinoma of the ovary.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/870531">Feature record</a> | <a href="/medgen?term=%22Ovarian%20papillary%20adenocarcinoma%22%5BClinical%20Features%5D%20OR%20870531%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_146260"><div><strong>Breast carcinoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>146260</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0678222</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The presence of a carcinoma of the breast.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/146260">Feature record</a> | <a href="/medgen?term=%22Breast%20carcinoma%22%5BClinical%20Features%5D%20OR%20146260%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of the breast</span><ul><li class="TLline">
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||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_146260" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Breast carcinoma</a></span></li></ul></li><li><span class="TLline">Neoplasm</span><ul><li class="TLline">
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<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_41680" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Dysgerminoma</a></span></li><li class="TLline">
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<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_870531" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ovarian papillary adenocarcinoma</a></span></li></ul></li></ul></div></div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0042065[DISCUI]&test_type=Clinical" ref="ncbi_uid=22583">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/22583" ref="tree=GTR&ncbi_uid=22583&link_uid=22583" title="View MedGen record for 'Neoplasm of the genitourinary tract'">Neoplasm of the genitourinary tract</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0474809[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=105374">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/105374" ref="tree=GTR&ncbi_uid=105374&link_uid=105374" title="View MedGen record for 'Endometrioid tumor'">Endometrioid tumor</a></span></li><li class="TLclosed"><span class="TLline"><a href="/medgen/69146" ref="tree=GTR&ncbi_uid=69146&link_uid=69146" title="View MedGen record for 'Kidney angiomyolipoma'">Kidney angiomyolipoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0376358[DISCUI]&test_type=Clinical" ref="ncbi_uid=138169">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=138169" target="_blank" href="/omim/176807">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=138169" ref="ncbi_uid=138169">V</a></span></span><span class="TLline"><a href="/medgen/138169" ref="tree=GTR&ncbi_uid=138169&link_uid=138169" title="View MedGen record for 'Malignant tumor of prostate'">Malignant tumor of prostate</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C2931456[DISCUI]&test_type=Clinical" ref="ncbi_uid=419810">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=419810" ref="ncbi_uid=419810">V</a></span></span><span class="TLline"><a href="/medgen/419810" ref="tree=GTR&ncbi_uid=419810&link_uid=419810" title="View MedGen record for 'Familial prostate cancer'">Familial prostate cancer</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0153594[DISCUI]&test_type=Clinical" ref="ncbi_uid=56313">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=56313" ref="ncbi_uid=56313">V</a></span></span><span class="TLline"><a href="/medgen/56313" ref="tree=GTR&ncbi_uid=56313&link_uid=56313" title="View MedGen record for 'Malignant tumor of testis'">Malignant tumor of testis</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1336708[DISCUI]&test_type=Clinical" ref="ncbi_uid=277809">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=277809" target="_blank" href="/omim/273300">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=277809" ref="ncbi_uid=277809">V</a></span></span><span class="TLline"><a href="/medgen/277809" ref="tree=GTR&ncbi_uid=277809&link_uid=277809" title="View MedGen record for 'Germ cell tumor of testis'">Germ cell tumor of testis</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=11371" target="_blank" href="/omim/273300">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/11371" ref="tree=GTR&ncbi_uid=11371&link_uid=11371" title="View MedGen record for 'Seminoma'">Seminoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=68669" target="_blank" href="/omim/273300">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/68669" ref="tree=GTR&ncbi_uid=68669&link_uid=68669" title="View MedGen record for 'Testicular teratoma'">Testicular teratoma</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=102281" target="_blank" href="/omim/191600">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/102281" ref="tree=GTR&ncbi_uid=102281&link_uid=102281" title="View MedGen record for 'Malignant tumor of ureter'">Malignant tumor of ureter</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0005684[DISCUI]&test_type=Clinical" ref="ncbi_uid=14150">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=14150" target="_blank" href="/omim/109800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=14150" ref="ncbi_uid=14150">V</a></span></span><span class="TLline"><a href="/medgen/14150" ref="tree=GTR&ncbi_uid=14150&link_uid=14150" title="View MedGen record for 'Malignant tumor of urinary bladder'">Malignant tumor of urinary bladder</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0699885[DISCUI]&test_type=Clinical" ref="ncbi_uid=147071">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/147071" ref="tree=GTR&ncbi_uid=147071&link_uid=147071" title="View MedGen record for 'Urinary bladder carcinoma'">Urinary bladder carcinoma</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0015558[DISCUI]&test_type=Clinical" ref="ncbi_uid=8775">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/8775" ref="tree=GTR&ncbi_uid=8775&link_uid=8775" title="View MedGen record for 'Neoplasm of fallopian tube'">Neoplasm of fallopian tube</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0042138[DISCUI]&test_type=Clinical" ref="ncbi_uid=12030">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=12030" ref="ncbi_uid=12030">V</a></span></span><span class="TLline"><a href="/medgen/12030" ref="tree=GTR&ncbi_uid=12030&link_uid=12030" title="View MedGen record for 'Neoplasm of uterus'">Neoplasm of uterus</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0014170[DISCUI]&test_type=Clinical" ref="ncbi_uid=8619">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/8619" ref="tree=GTR&ncbi_uid=8619&link_uid=8619" title="View MedGen record for 'Endometrium neoplasm'">Endometrium neoplasm</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0007873[DISCUI]&test_type=Clinical" ref="ncbi_uid=40201">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/40201" ref="tree=GTR&ncbi_uid=40201&link_uid=40201" title="View MedGen record for 'Neoplasm of uterine cervix'">Neoplasm of uterine cervix</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/91094" ref="tree=GTR&ncbi_uid=91094&link_uid=91094" title="View MedGen record for 'Oncocytoma of kidney'">Oncocytoma of kidney</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0919267[DISCUI]&test_type=Clinical" ref="ncbi_uid=181539">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=181539" ref="ncbi_uid=181539">V</a></span></span><span class="TLline"><a href="/medgen/181539" ref="tree=GTR&ncbi_uid=181539&link_uid=181539" title="View MedGen record for 'Ovarian neoplasm'">Ovarian neoplasm</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1333992[DISCUI]&test_type=Clinical" ref="ncbi_uid=272713">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=272713" ref="ncbi_uid=272713">V</a></span></span><span class="TLline"><a href="/medgen/272713" ref="tree=GTR&ncbi_uid=272713&link_uid=272713" title="View MedGen record for 'Familial ovarian carcinoma'">Familial ovarian carcinoma</a></span></li><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1140680[DISCUI]&test_type=Clinical" ref="ncbi_uid=216027">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=216027" target="_blank" href="/omim/167000">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=216027" ref="ncbi_uid=216027">V</a></span></span><span class="TLline">Ovarian cancer</span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1868358[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=358303">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=358303" target="_blank" href="/omim/171834">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=358303" ref="ncbi_uid=358303">V</a></span></span><span class="TLline"><a href="/medgen/358303" ref="tree=GTR&ncbi_uid=358303&link_uid=358303" title="View MedGen record for 'OVARIAN CANCER, EPITHELIAL, SOMATIC'">OVARIAN CANCER, EPITHELIAL, SOMATIC</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1336839[DISCUI]&test_type=Clinical" ref="ncbi_uid=237026">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=237026" target="_blank" href="/omim/164860">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=237026" ref="ncbi_uid=237026">V</a></span></span><span class="TLline"><a href="/medgen/237026" ref="tree=GTR&ncbi_uid=237026&link_uid=237026" title="View MedGen record for 'Papillary renal cell carcinoma type 1'">Papillary renal cell carcinoma type 1</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1266142[DISCUI]&test_type=Clinical" ref="ncbi_uid=690113">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/690113" ref="tree=GTR&ncbi_uid=690113&link_uid=690113" title="View MedGen record for 'Renal hamartoma'">Renal hamartoma</a></span></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/232130" ref="tree=MeSH" title="MedGen record for Disorder by Site">Disorder by Site</a></span><ul><li><span class="TLline"><a href="/medgen/508335" ref="tree=MeSH" title="MedGen record for Disorder of the genitourinary system">Disorder of the genitourinary system</a></span><ul><li><span class="TLline"><a href="/medgen/61253" ref="tree=MeSH" title="MedGen record for Reproductive system disorder">Reproductive system disorder</a></span><ul><li><span class="TLline"><a href="/medgen/65928" ref="tree=MeSH" title="MedGen record for Female reproductive system disorder">Female reproductive system disorder</a></span><ul><li><span class="TLline"><a href="/medgen/9004" ref="tree=MeSH" title="MedGen record for Female reproductive system neoplasm">Female reproductive system neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/195944" ref="tree=MeSH" title="MedGen record for Female reproductive organ cancer">Female reproductive organ cancer</a></span><ul><li><span class="matched_ds">Ovarian cancer</span><ul><li><span class="TLline"><a href="/medgen/266966" ref="tree=MeSH" title="MedGen record for Adenocarcinofibroma">Adenocarcinofibroma</a></span><ul><li><span class="TLline"><a href="/medgen/384483" ref="tree=MeSH" title="MedGen record for Ovarian clear cell malignant adenofibroma">Ovarian clear cell malignant adenofibroma</a></span></li><li><span class="TLline"><a href="/medgen/384497" ref="tree=MeSH" title="MedGen record for Ovarian mucinous adenocarcinofibroma">Ovarian mucinous adenocarcinofibroma</a></span></li><li><span class="TLline"><a href="/medgen/473548" ref="tree=MeSH" title="MedGen record for Ovarian Serous Adenocarcinofibroma">Ovarian Serous Adenocarcinofibroma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/91089" ref="tree=MeSH" title="MedGen record for Choriocarcinoma of ovary">Choriocarcinoma of ovary</a></span><ul><li><span class="TLline"><a href="/medgen/274586" ref="tree=MeSH" title="MedGen record for Gestational ovarian choriocarcinoma">Gestational ovarian choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/274798" ref="tree=MeSH" title="MedGen record for Non-gestational ovarian choriocarcinoma">Non-gestational ovarian choriocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/234135" ref="tree=MeSH" title="MedGen record for Childhood choriocarcinoma of the ovary">Childhood choriocarcinoma of the ovary</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163165" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Choriocarcinoma">Stage I Ovarian Choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/167734" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Choriocarcinoma">Stage II Ovarian Choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/163166" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Choriocarcinoma">Stage III Ovarian Choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/167735" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Choriocarcinoma">Stage IV Ovarian Choriocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1737130" ref="tree=MeSH" title="MedGen record for Extrarenal Rhabdoid Tumor of the Ovary">Extrarenal Rhabdoid Tumor of the Ovary</a></span><ul><li><span class="TLline"><a href="/medgen/1734687" ref="tree=MeSH" title="MedGen record for Recurrent Extrarenal Rhabdoid Tumor of the Ovary">Recurrent Extrarenal Rhabdoid Tumor of the Ovary</a></span></li><li><span class="TLline"><a href="/medgen/1749849" ref="tree=MeSH" title="MedGen record for Refractory Extrarenal Rhabdoid Tumor of the Ovary">Refractory Extrarenal Rhabdoid Tumor of the Ovary</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87544" ref="tree=MeSH" title="MedGen record for Malignant germ cell tumor of ovary">Malignant germ cell tumor of ovary</a></span><ul><li><span class="TLline"><a href="/medgen/164003" ref="tree=MeSH" title="MedGen record for Childhood Malignant Ovarian Germ Cell Tumor">Childhood Malignant Ovarian Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/232352" ref="tree=MeSH" title="MedGen record for Childhood ovarian embryonal carcinoma">Childhood ovarian embryonal carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/896650" ref="tree=MeSH" title="MedGen record for Childhood Ovarian Mixed Germ Cell Tumor">Childhood Ovarian Mixed Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/234136" ref="tree=MeSH" title="MedGen record for Childhood ovarian yolk sac tumor">Childhood ovarian yolk sac tumor</a></span></li><li><span class="TLline"><a href="/medgen/272465" ref="tree=MeSH" title="MedGen record for Pediatric ovarian dysgerminoma">Pediatric ovarian dysgerminoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/798473" ref="tree=MeSH" title="MedGen record for Malignant dysgerminomatous germ cell tumor of ovary">Malignant dysgerminomatous germ cell tumor of ovary</a></span></li><li><span class="TLline"><a href="/medgen/1826164" ref="tree=MeSH" title="MedGen record for Malignant non-dysgerminomatous germ cell tumor of ovary">Malignant non-dysgerminomatous germ cell tumor of ovary</a></span></li><li><span class="TLline"><a href="/medgen/1657209" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Teratoma">Malignant Ovarian Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/137777" ref="tree=MeSH" title="MedGen record for Malignant struma ovarii">Malignant struma ovarii</a></span></li><li><span class="TLline"><a href="/medgen/275291" ref="tree=MeSH" title="MedGen record for Ovarian primitive germ cell tumor">Ovarian primitive germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/83414" ref="tree=MeSH" title="MedGen record for Dysgerminoma of ovary">Dysgerminoma of ovary</a></span></li><li><span class="TLline"><a href="/medgen/83602" ref="tree=MeSH" title="MedGen record for Ovarian mixed germ cell neoplasm">Ovarian mixed germ cell neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/769623" ref="tree=MeSH" title="MedGen record for Ovarian Non-Dysgerminomatous Germ Cell Tumor">Ovarian Non-Dysgerminomatous Germ Cell Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/906353" ref="tree=MeSH" title="MedGen record for Primary non-gestational choriocarcinoma of ovary">Primary non-gestational choriocarcinoma of ovary</a></span></li><li><span class="TLline"><a href="/medgen/79058" ref="tree=MeSH" title="MedGen record for Recurrent Ovarian Germ Cell Tumor">Recurrent Ovarian Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/124681" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Germ Cell Tumor AJCC v6 and v7">Stage I Ovarian Germ Cell Tumor AJCC v6 and v7</a></span><ul><li><span class="TLline"><a href="/medgen/1661411" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Dysgerminoma AJCC v6 and v7">Stage I Ovarian Dysgerminoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277761" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234359" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Polyembryoma AJCC v6 and v7">Stage I Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1656269" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Teratoma AJCC v6 and v7">Stage I Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277762" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236856" ref="tree=MeSH" title="MedGen record for Stage IA Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IA Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277680" ref="tree=MeSH" title="MedGen record for Stage IB Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IB Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236865" ref="tree=MeSH" title="MedGen record for Stage IC Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IC Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/76052" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Germ Cell Tumor AJCC v6 and v7">Stage II Ovarian Germ Cell Tumor AJCC v6 and v7</a></span><ul><li><span class="TLline"><a href="/medgen/1670106" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Dysgerminoma AJCC v6 and v7">Stage II Ovarian Dysgerminoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236906" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236907" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Polyembryoma AJCC v6 and v7">Stage II Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1663837" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Teratoma AJCC v6 and v7">Stage II Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234856" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277689" ref="tree=MeSH" title="MedGen record for Stage IIA Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIA Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277695" ref="tree=MeSH" title="MedGen record for Stage IIB Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIB Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/233492" ref="tree=MeSH" title="MedGen record for Stage IIC Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIC Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124682" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Germ Cell Tumor AJCC v6 and v7">Stage III Ovarian Germ Cell Tumor AJCC v6 and v7</a></span><ul><li><span class="TLline"><a href="/medgen/1669220" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Dysgerminoma AJCC v6 and v7">Stage III Ovarian Dysgerminoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236896" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277714" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Polyembryoma AJCC v6 and v7">Stage III Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1648756" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Teratoma AJCC v6 and v7">Stage III Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236897" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234840" ref="tree=MeSH" title="MedGen record for Stage IIIA Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIIA Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236887" ref="tree=MeSH" title="MedGen record for Stage IIIB Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIIB Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/233497" ref="tree=MeSH" title="MedGen record for Stage IIIC Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIIC Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1669130" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IV Ovarian Germ Cell Tumor AJCC v6 and v7</a></span><ul><li><span class="TLline"><a href="/medgen/1665964" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Dysgerminoma AJCC v6 and v7">Stage IV Ovarian Dysgerminoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234888" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234889" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Polyembryoma AJCC v6 and v7">Stage IV Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1661846" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Teratoma AJCC v6 and v7">Stage IV Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234890" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/273560" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Epithelial Tumor">Malignant Ovarian Epithelial Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/309396" ref="tree=MeSH" title="MedGen record for Malignant ovarian serous tumor">Malignant ovarian serous tumor</a></span><ul><li><span class="TLline"><a href="/medgen/233278" ref="tree=MeSH" title="MedGen record for Ovarian serous adenocarcinoma">Ovarian serous adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/274767" ref="tree=MeSH" title="MedGen record for Mucinous ovarian cancer">Mucinous ovarian cancer</a></span><ul><li><span class="TLline"><a href="/medgen/235418" ref="tree=MeSH" title="MedGen record for Ovarian mucinous adenocarcinoma">Ovarian mucinous adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1648335" ref="tree=MeSH" title="MedGen record for Ovarian carcinoma">Ovarian carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/272713" ref="tree=MeSH" title="MedGen record for Familial ovarian carcinoma">Familial ovarian carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/90793" ref="tree=MeSH" title="MedGen record for Malignant ovarian Brenner tumor">Malignant ovarian Brenner tumor</a></span></li><li><span class="TLline"><a href="/medgen/78864" ref="tree=MeSH" title="MedGen record for Metastatic Ovarian Carcinoma">Metastatic Ovarian Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1792731" ref="tree=MeSH" title="MedGen record for Microsatellite Stable Ovarian Carcinoma">Microsatellite Stable Ovarian Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/181757" ref="tree=MeSH" title="MedGen record for Ovarian adenocarcinoma">Ovarian adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/925360" ref="tree=MeSH" title="MedGen record for Ovarian Cancer by AJCC v6 and v7 Stage">Ovarian Cancer by AJCC v6 and v7 Stage</a></span></li><li><span class="TLline"><a href="/medgen/1633131" ref="tree=MeSH" title="MedGen record for Ovarian Cancer by AJCC v8 Stage">Ovarian Cancer by AJCC v8 Stage</a></span></li><li><span class="TLline"><a href="/medgen/925359" ref="tree=MeSH" title="MedGen record for Ovarian Cancer by FIGO Stage">Ovarian Cancer by FIGO Stage</a></span></li><li><span class="TLline"><a href="/medgen/1792061" ref="tree=MeSH" title="MedGen record for Ovarian Dedifferentiated Carcinoma">Ovarian Dedifferentiated Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1771718" ref="tree=MeSH" title="MedGen record for Ovarian Neuroendocrine Carcinoma">Ovarian Neuroendocrine Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1651770" ref="tree=MeSH" title="MedGen record for Ovarian seromucinous carcinoma">Ovarian seromucinous carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/389177" ref="tree=MeSH" title="MedGen record for Ovarian small cell carcinoma">Ovarian small cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/384474" ref="tree=MeSH" title="MedGen record for Ovarian squamous cell carcinoma">Ovarian squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233811" ref="tree=MeSH" title="MedGen record for Ovarian transitional cell carcinoma">Ovarian transitional cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1692268" ref="tree=MeSH" title="MedGen record for Platinum-Sensitive Ovarian Carcinoma">Platinum-Sensitive Ovarian Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/78865" ref="tree=MeSH" title="MedGen record for Recurrent Ovarian Carcinoma">Recurrent Ovarian Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1651209" ref="tree=MeSH" title="MedGen record for Refractory Ovarian Carcinoma">Refractory Ovarian Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/83410" ref="tree=MeSH" title="MedGen record for Undifferentiated ovarian carcinoma">Undifferentiated ovarian carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1715019" ref="tree=MeSH" title="MedGen record for Unresectable Ovarian Carcinoma">Unresectable Ovarian Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/276544" ref="tree=MeSH" title="MedGen record for Ovarian clear cell cancer">Ovarian clear cell cancer</a></span><ul><li><span class="TLline"><a href="/medgen/276659" ref="tree=MeSH" title="MedGen record for Ovarian clear cell adenocarcinoma">Ovarian clear cell adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/276545" ref="tree=MeSH" title="MedGen record for Ovarian endometrial cancer">Ovarian endometrial cancer</a></span><ul><li><span class="TLline"><a href="/medgen/140705" ref="tree=MeSH" title="MedGen record for Ovarian carcinosarcoma">Ovarian carcinosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/91087" ref="tree=MeSH" title="MedGen record for Ovarian endometrioid adenocarcinoma">Ovarian endometrioid adenocarcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/233667" ref="tree=MeSH" title="MedGen record for Malignant sex cord stromal tumor of ovary">Malignant sex cord stromal tumor of ovary</a></span><ul><li><span class="TLline"><a href="/medgen/138043" ref="tree=MeSH" title="MedGen record for Maligant granulosa cell tumor of ovary">Maligant granulosa cell tumor of ovary</a></span><ul><li><span class="TLline"><a href="/medgen/1695109" ref="tree=MeSH" title="MedGen record for Recurrent Malignant Ovarian Granulosa Cell Tumor">Recurrent Malignant Ovarian Granulosa Cell Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/412169" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Steroid Cell Tumor">Malignant Ovarian Steroid Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/83139" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Thecoma">Malignant Ovarian Thecoma</a></span><ul><li><span class="TLline"><a href="/medgen/233666" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Luteinized Thecoma">Malignant Ovarian Luteinized Thecoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1825991" ref="tree=MeSH" title="MedGen record for Malignant Sertoli-Leydig cell tumor of ovary">Malignant Sertoli-Leydig cell tumor of ovary</a></span></li><li><span class="TLline"><a href="/medgen/83412" ref="tree=MeSH" title="MedGen record for Ovarian gynandroblastoma">Ovarian gynandroblastoma</a></span></li><li><span class="TLline"><a href="/medgen/362651" ref="tree=MeSH" title="MedGen record for Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor">Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/307990" ref="tree=MeSH" title="MedGen record for Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor, Variant with Heterologous Elements">Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor, Variant with Heterologous Elements</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/904268" ref="tree=MeSH" title="MedGen record for Theca steroid-producing cell malignant tumor of ovary, not further specified">Theca steroid-producing cell malignant tumor of ovary, not further specified</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/777081" ref="tree=MeSH" title="MedGen record for Metastatic Malignant Neoplasm in the Ovary">Metastatic Malignant Neoplasm in the Ovary</a></span><ul><li><span class="TLline"><a href="/medgen/9652" ref="tree=MeSH" title="MedGen record for Krukenberg carcinoma">Krukenberg carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/276669" ref="tree=MeSH" title="MedGen record for Ovarian lymphoma">Ovarian lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/274089" ref="tree=MeSH" title="MedGen record for Ovarian malignant mesothelioma">Ovarian malignant mesothelioma</a></span></li><li><span class="TLline"><a href="/medgen/1790038" ref="tree=MeSH" title="MedGen record for Ovarian melanoma">Ovarian melanoma</a></span></li><li><span class="TLline"><a href="/medgen/1792161" ref="tree=MeSH" title="MedGen record for Ovarian Neuroectodermal-Type Tumor">Ovarian Neuroectodermal-Type Tumor</a></span></li><li><span class="TLline"><a href="/medgen/128881" ref="tree=MeSH" title="MedGen record for Ovarian sarcoma">Ovarian sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/233808" ref="tree=MeSH" title="MedGen record for Liposarcoma of the ovary">Liposarcoma of the ovary</a></span><ul><li><span class="TLline"><a href="/medgen/235420" ref="tree=MeSH" title="MedGen record for Ovarian myxoid liposarcoma">Ovarian myxoid liposarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/277458" ref="tree=MeSH" title="MedGen record for Ovarian adenosarcoma">Ovarian adenosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233805" ref="tree=MeSH" title="MedGen record for Ovarian angiosarcoma">Ovarian angiosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/235417" ref="tree=MeSH" title="MedGen record for Ovarian Fibrosarcoma">Ovarian Fibrosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/276498" ref="tree=MeSH" title="MedGen record for Ovarian Low Grade Endometrioid Stromal Sarcoma">Ovarian Low Grade Endometrioid Stromal Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/384493" ref="tree=MeSH" title="MedGen record for Ovarian Undifferentiated Sarcoma">Ovarian Undifferentiated Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233275" ref="tree=MeSH" title="MedGen record for Ovary leiomyosarcoma">Ovary leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233277" ref="tree=MeSH" title="MedGen record for Ovary rhabdomyosarcoma">Ovary rhabdomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/275296" ref="tree=MeSH" title="MedGen record for Ovarian Wilms tumor">Ovarian Wilms tumor</a></span></li><li><span class="TLline"><a href="/medgen/1709430" ref="tree=MeSH" title="MedGen record for Solid Pseudopapillary Neoplasm of the Ovary">Solid Pseudopapillary Neoplasm of the Ovary</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/37856201">NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2024.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Daly MB,
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Pal T,
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Maxwell KN,
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Churpek J,
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||
Kohlmann W,
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||
AlHilli Z,
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||
Arun B,
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||
Buys SS,
|
||
Cheng H,
|
||
Domchek SM,
|
||
Friedman S,
|
||
Giri V,
|
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Goggins M,
|
||
Hagemann A,
|
||
Hendrix A,
|
||
Hutton ML,
|
||
Karlan BY,
|
||
Kassem N,
|
||
Khan S,
|
||
Khoury K,
|
||
Kurian AW,
|
||
Laronga C,
|
||
Mak JS,
|
||
Mansour J,
|
||
McDonnell K,
|
||
Menendez CS,
|
||
Merajver SD,
|
||
Norquist BS,
|
||
Offit K,
|
||
Rash D,
|
||
Reiser G,
|
||
Senter-Jamieson L,
|
||
Shannon KM,
|
||
Visvanathan K,
|
||
Welborn J,
|
||
Wick MJ,
|
||
Wood M,
|
||
Yurgelun MB,
|
||
Dwyer MA,
|
||
Darlow SD</span><br />
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<span class="medgenPMjournal">J Natl Compr Canc Netw</span>
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2023 Oct;21(10):1000-1010.
|
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doi: 10.6004/jnccn.2023.0051.
|
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<span class="bold">PMID: </span><a href="/pubmed/37856201" target="_blank">37856201</a></div>
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|
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<div class="nl"><a target="_blank" href="/pubmed/33406487">Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Daly MB,
|
||
Pal T,
|
||
Berry MP,
|
||
Buys SS,
|
||
Dickson P,
|
||
Domchek SM,
|
||
Elkhanany A,
|
||
Friedman S,
|
||
Goggins M,
|
||
Hutton ML;
|
||
CGC,
|
||
Karlan BY,
|
||
Khan S,
|
||
Klein C,
|
||
Kohlmann W;
|
||
CGC,
|
||
Kurian AW,
|
||
Laronga C,
|
||
Litton JK,
|
||
Mak JS;
|
||
LCGC,
|
||
Menendez CS,
|
||
Merajver SD,
|
||
Norquist BS,
|
||
Offit K,
|
||
Pederson HJ,
|
||
Reiser G;
|
||
CGC,
|
||
Senter-Jamieson L;
|
||
CGC,
|
||
Shannon KM,
|
||
Shatsky R,
|
||
Visvanathan K,
|
||
Weitzel JN,
|
||
Wick MJ,
|
||
Wisinski KB,
|
||
Yurgelun MB,
|
||
Darlow SD,
|
||
Dwyer MA</span><br />
|
||
<span class="medgenPMjournal">J Natl Compr Canc Netw</span>
|
||
2021 Jan 6;19(1):77-102.
|
||
doi: 10.6004/jnccn.2021.0001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33406487" target="_blank">33406487</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29420391">Clinical Management of Endometriosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Falcone T,
|
||
Flyckt R</span><br />
|
||
<span class="medgenPMjournal">Obstet Gynecol</span>
|
||
2018 Mar;131(3):557-571.
|
||
doi: 10.1097/AOG.0000000000002469.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29420391" target="_blank">29420391</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22ovarian%20cancer%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (4182)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/ovarian.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/cg122" target="_blank">UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38353066">Screening and prevention of ovarian cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sideris M,
|
||
Menon U,
|
||
Manchanda R</span><br />
|
||
<span class="medgenPMjournal">Med J Aust</span>
|
||
2024 Mar 18;220(5):264-274.
|
||
Epub 2024 Feb 14
|
||
doi: 10.5694/mja2.52227.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38353066" target="_blank">38353066</a><a href="/pmc/articles/PMC7617385" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36233339">Molecular Biomarkers for the Early Detection of Ovarian Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang R,
|
||
Siu MKY,
|
||
Ngan HYS,
|
||
Chan KKL</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2022 Oct 10;23(19)
|
||
doi: 10.3390/ijms231912041.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36233339" target="_blank">36233339</a><a href="/pmc/articles/PMC9569881" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35322413">Ovarian cancer today and tomorrow: A global assessment by world region and Human Development Index using GLOBOCAN 2020.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cabasag CJ,
|
||
Fagan PJ,
|
||
Ferlay J,
|
||
Vignat J,
|
||
Laversanne M,
|
||
Liu L,
|
||
van der Aa MA,
|
||
Bray F,
|
||
Soerjomataram I</span><br />
|
||
<span class="medgenPMjournal">Int J Cancer</span>
|
||
2022 Nov 1;151(9):1535-1541.
|
||
Epub 2022 Mar 30
|
||
doi: 10.1002/ijc.34002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35322413" target="_blank">35322413</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32468105">Early detection of ovarian cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Forstner R</span><br />
|
||
<span class="medgenPMjournal">Eur Radiol</span>
|
||
2020 Oct;30(10):5370-5373.
|
||
Epub 2020 May 28
|
||
doi: 10.1007/s00330-020-06937-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32468105" target="_blank">32468105</a><a href="/pmc/articles/PMC7476911" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30867104">Ovarian Cancer: An Integrated Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Stewart C,
|
||
Ralyea C,
|
||
Lockwood S</span><br />
|
||
<span class="medgenPMjournal">Semin Oncol Nurs</span>
|
||
2019 Apr;35(2):151-156.
|
||
Epub 2019 Mar 11
|
||
doi: 10.1016/j.soncn.2019.02.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30867104" target="_blank">30867104</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20cancer%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (23208)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36233339">Molecular Biomarkers for the Early Detection of Ovarian Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang R,
|
||
Siu MKY,
|
||
Ngan HYS,
|
||
Chan KKL</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2022 Oct 10;23(19)
|
||
doi: 10.3390/ijms231912041.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36233339" target="_blank">36233339</a><a href="/pmc/articles/PMC9569881" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34918284">Clinical Staging of Ovarian Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">O'Shea AS</span><br />
|
||
<span class="medgenPMjournal">Methods Mol Biol</span>
|
||
2022;2424:3-10.
|
||
doi: 10.1007/978-1-0716-1956-8_1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34918284" target="_blank">34918284</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32606233">Ovarian Cancer: An Overview.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Penny SM</span><br />
|
||
<span class="medgenPMjournal">Radiol Technol</span>
|
||
2020 Jul;91(6):561-575.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32606233" target="_blank">32606233</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32468105">Early detection of ovarian cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Forstner R</span><br />
|
||
<span class="medgenPMjournal">Eur Radiol</span>
|
||
2020 Oct;30(10):5370-5373.
|
||
Epub 2020 May 28
|
||
doi: 10.1007/s00330-020-06937-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32468105" target="_blank">32468105</a><a href="/pmc/articles/PMC7476911" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30867104">Ovarian Cancer: An Integrated Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Stewart C,
|
||
Ralyea C,
|
||
Lockwood S</span><br />
|
||
<span class="medgenPMjournal">Semin Oncol Nurs</span>
|
||
2019 Apr;35(2):151-156.
|
||
Epub 2019 Mar 11
|
||
doi: 10.1016/j.soncn.2019.02.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30867104" target="_blank">30867104</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20cancer%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (21448)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38583868">Cancer Stage Compared With Mortality as End Points in Randomized Clinical Trials of Cancer Screening: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Feng X,
|
||
Zahed H,
|
||
Onwuka J,
|
||
Callister MEJ,
|
||
Johansson M,
|
||
Etzioni R,
|
||
Robbins HA</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2024 Jun 11;331(22):1910-1917.
|
||
doi: 10.1001/jama.2024.5814.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38583868" target="_blank">38583868</a><a href="/pmc/articles/PMC11000135" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36116421">Hyperthermic intraperitoneal chemotherapy (HIPEC) for the management of primary advanced and recurrent ovarian cancer: a systematic review and meta-analysis of randomized trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Filis P,
|
||
Mauri D,
|
||
Markozannes G,
|
||
Tolia M,
|
||
Filis N,
|
||
Tsilidis K</span><br />
|
||
<span class="medgenPMjournal">ESMO Open</span>
|
||
2022 Oct;7(5):100586.
|
||
Epub 2022 Sep 16
|
||
doi: 10.1016/j.esmoop.2022.100586.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36116421" target="_blank">36116421</a><a href="/pmc/articles/PMC9588894" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32335505">Bevacizumab (Avastin®) in cancer treatment: A review of 15 years of clinical experience and future outlook.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Garcia J,
|
||
Hurwitz HI,
|
||
Sandler AB,
|
||
Miles D,
|
||
Coleman RL,
|
||
Deurloo R,
|
||
Chinot OL</span><br />
|
||
<span class="medgenPMjournal">Cancer Treat Rev</span>
|
||
2020 Jun;86:102017.
|
||
Epub 2020 Mar 26
|
||
doi: 10.1016/j.ctrv.2020.102017.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32335505" target="_blank">32335505</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30470299">Improving Oncology Clinical Trial Participation and Experience.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zaharoff B,
|
||
Cipra S</span><br />
|
||
<span class="medgenPMjournal">Trends Cancer</span>
|
||
2018 Dec;4(12):793-796.
|
||
Epub 2018 Nov 13
|
||
doi: 10.1016/j.trecan.2018.10.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30470299" target="_blank">30470299</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22180408">New drugs for ovarian cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bell-McGuinn K,
|
||
Konner J,
|
||
Tew W,
|
||
Spriggs DR</span><br />
|
||
<span class="medgenPMjournal">Ann Oncol</span>
|
||
2011 Dec;22 Suppl 8:viii77-viii82.
|
||
doi: 10.1093/annonc/mdr531.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22180408" target="_blank">22180408</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20cancer%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (18392)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35322413">Ovarian cancer today and tomorrow: A global assessment by world region and Human Development Index using GLOBOCAN 2020.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cabasag CJ,
|
||
Fagan PJ,
|
||
Ferlay J,
|
||
Vignat J,
|
||
Laversanne M,
|
||
Liu L,
|
||
van der Aa MA,
|
||
Bray F,
|
||
Soerjomataram I</span><br />
|
||
<span class="medgenPMjournal">Int J Cancer</span>
|
||
2022 Nov 1;151(9):1535-1541.
|
||
Epub 2022 Mar 30
|
||
doi: 10.1002/ijc.34002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35322413" target="_blank">35322413</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31046082">Antitumor activity and safety of pembrolizumab in patients with advanced recurrent ovarian cancer: results from the phase II KEYNOTE-100 study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Matulonis UA,
|
||
Shapira-Frommer R,
|
||
Santin AD,
|
||
Lisyanskaya AS,
|
||
Pignata S,
|
||
Vergote I,
|
||
Raspagliesi F,
|
||
Sonke GS,
|
||
Birrer M,
|
||
Provencher DM,
|
||
Sehouli J,
|
||
Colombo N,
|
||
González-Martín A,
|
||
Oaknin A,
|
||
Ottevanger PB,
|
||
Rudaitis V,
|
||
Katchar K,
|
||
Wu H,
|
||
Keefe S,
|
||
Ruman J,
|
||
Ledermann JA</span><br />
|
||
<span class="medgenPMjournal">Ann Oncol</span>
|
||
2019 Jul 1;30(7):1080-1087.
|
||
doi: 10.1093/annonc/mdz135.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31046082" target="_blank">31046082</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28470962">Do patients have worse outcomes in heart failure than in cancer? A primary care-based cohort study with 10-year follow-up in Scotland.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mamas MA,
|
||
Sperrin M,
|
||
Watson MC,
|
||
Coutts A,
|
||
Wilde K,
|
||
Burton C,
|
||
Kadam UT,
|
||
Kwok CS,
|
||
Clark AB,
|
||
Murchie P,
|
||
Buchan I,
|
||
Hannaford PC,
|
||
Myint PK</span><br />
|
||
<span class="medgenPMjournal">Eur J Heart Fail</span>
|
||
2017 Sep;19(9):1095-1104.
|
||
Epub 2017 May 3
|
||
doi: 10.1002/ejhf.822.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28470962" target="_blank">28470962</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21803880">Bevacizumab-induced bowel perforation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sliesoraitis S,
|
||
Tawfik B</span><br />
|
||
<span class="medgenPMjournal">J Am Osteopath Assoc</span>
|
||
2011 Jul;111(7):437-41.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21803880" target="_blank">21803880</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9484630">Progress in ovarian cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen LM,
|
||
Berek JS</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Obstet Gynecol</span>
|
||
1998 Feb;10(1):51-5.
|
||
doi: 10.1097/00001703-199802000-00010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9484630" target="_blank">9484630</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20cancer%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (19384)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28443762">Prediction of therapy response in ovarian cancer: Where are we now?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">El Bairi K,
|
||
Amrani M,
|
||
Kandhro AH,
|
||
Afqir S</span><br />
|
||
<span class="medgenPMjournal">Crit Rev Clin Lab Sci</span>
|
||
2017 Jun;54(4):233-266.
|
||
Epub 2017 Apr 26
|
||
doi: 10.1080/10408363.2017.1313190.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28443762" target="_blank">28443762</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26976419">Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tung N,
|
||
Lin NU,
|
||
Kidd J,
|
||
Allen BA,
|
||
Singh N,
|
||
Wenstrup RJ,
|
||
Hartman AR,
|
||
Winer EP,
|
||
Garber JE</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2016 May 1;34(13):1460-8.
|
||
Epub 2016 Mar 14
|
||
doi: 10.1200/JCO.2015.65.0747.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26976419" target="_blank">26976419</a><a href="/pmc/articles/PMC4872307" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25320247">Evaluating the risk of ovarian cancer before surgery using the ADNEX model to differentiate between benign, borderline, early and advanced stage invasive, and secondary metastatic tumours: prospective multicentre diagnostic study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Van Calster B,
|
||
Van Hoorde K,
|
||
Valentin L,
|
||
Testa AC,
|
||
Fischerova D,
|
||
Van Holsbeke C,
|
||
Savelli L,
|
||
Franchi D,
|
||
Epstein E,
|
||
Kaijser J,
|
||
Van Belle V,
|
||
Czekierdowski A,
|
||
Guerriero S,
|
||
Fruscio R,
|
||
Lanzani C,
|
||
Scala F,
|
||
Bourne T,
|
||
Timmerman D;
|
||
International Ovarian Tumour Analysis Group</span><br />
|
||
<span class="medgenPMjournal">BMJ</span>
|
||
2014 Oct 15;349:g5920.
|
||
doi: 10.1136/bmj.g5920.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25320247" target="_blank">25320247</a><a href="/pmc/articles/PMC4198550" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18504770">Simple ultrasound-based rules for the diagnosis of ovarian cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Timmerman D,
|
||
Testa AC,
|
||
Bourne T,
|
||
Ameye L,
|
||
Jurkovic D,
|
||
Van Holsbeke C,
|
||
Paladini D,
|
||
Van Calster B,
|
||
Vergote I,
|
||
Van Huffel S,
|
||
Valentin L</span><br />
|
||
<span class="medgenPMjournal">Ultrasound Obstet Gynecol</span>
|
||
2008 Jun;31(6):681-90.
|
||
doi: 10.1002/uog.5365.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18504770" target="_blank">18504770</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12797860">Screening for ovarian cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Anderiesz C,
|
||
Quinn MA</span><br />
|
||
<span class="medgenPMjournal">Med J Aust</span>
|
||
2003 Jun 16;178(12):655-6.
|
||
doi: 10.5694/j.1326-5377.2003.tb05399.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12797860" target="_blank">12797860</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20cancer%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (18154)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38409030">PARP inhibitor era in ovarian cancer treatment: a systematic review and meta-analysis of randomized controlled trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baradács I,
|
||
Teutsch B,
|
||
Váradi A,
|
||
Bilá A,
|
||
Vincze Á,
|
||
Hegyi P,
|
||
Fazekas T,
|
||
Komoróczy B,
|
||
Nyirády P,
|
||
Ács N,
|
||
Bánhidy F,
|
||
Lintner B</span><br />
|
||
<span class="medgenPMjournal">J Ovarian Res</span>
|
||
2024 Feb 26;17(1):53.
|
||
doi: 10.1186/s13048-024-01362-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38409030" target="_blank">38409030</a><a href="/pmc/articles/PMC10895809" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37672283">Salpingectomy for the Primary Prevention of Ovarian Cancer: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kahn RM,
|
||
Gordhandas S,
|
||
Godwin K,
|
||
Stone RL,
|
||
Worley MJ Jr,
|
||
Lu KH,
|
||
Long Roche KC</span><br />
|
||
<span class="medgenPMjournal">JAMA Surg</span>
|
||
2023 Nov 1;158(11):1204-1211.
|
||
doi: 10.1001/jamasurg.2023.4164.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37672283" target="_blank">37672283</a><a href="/pmc/articles/PMC11185162" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36116421">Hyperthermic intraperitoneal chemotherapy (HIPEC) for the management of primary advanced and recurrent ovarian cancer: a systematic review and meta-analysis of randomized trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Filis P,
|
||
Mauri D,
|
||
Markozannes G,
|
||
Tolia M,
|
||
Filis N,
|
||
Tsilidis K</span><br />
|
||
<span class="medgenPMjournal">ESMO Open</span>
|
||
2022 Oct;7(5):100586.
|
||
Epub 2022 Sep 16
|
||
doi: 10.1016/j.esmoop.2022.100586.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36116421" target="_blank">36116421</a><a href="/pmc/articles/PMC9588894" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34758846">Investigation on factors associated with ovarian cancer: an umbrella review of systematic review and meta-analyses.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tanha K,
|
||
Mottaghi A,
|
||
Nojomi M,
|
||
Moradi M,
|
||
Rajabzadeh R,
|
||
Lotfi S,
|
||
Janani L</span><br />
|
||
<span class="medgenPMjournal">J Ovarian Res</span>
|
||
2021 Nov 11;14(1):153.
|
||
doi: 10.1186/s13048-021-00911-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34758846" target="_blank">34758846</a><a href="/pmc/articles/PMC8582179" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31986064">Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer: ASCO Guideline.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Konstantinopoulos PA,
|
||
Norquist B,
|
||
Lacchetti C,
|
||
Armstrong D,
|
||
Grisham RN,
|
||
Goodfellow PJ,
|
||
Kohn EC,
|
||
Levine DA,
|
||
Liu JF,
|
||
Lu KH,
|
||
Sparacio D,
|
||
Annunziata CM</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2020 Apr 10;38(11):1222-1245.
|
||
Epub 2020 Jan 27
|
||
doi: 10.1200/JCO.19.02960.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31986064" target="_blank">31986064</a><a href="/pmc/articles/PMC8842911" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20cancer%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (916)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
||
<div class="portlet mgSection" id="ID_113">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul id="my-toc"></ul></div>
|
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</div>
|
||
|
||
<div class="portlet mgSection" id="ID_106">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C1140680%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (14)</a></li>
|
||
<li><a href="/gtr/tests?term=C1140680%5bDISCUI%5d&filter=method%3A2%5F29" target="_blank">Detection of homozygosity (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C1140680%5bDISCUI%5d&filter=method%3A2%5F12" target="_blank">Microsatellite instability testing (MSI) (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C1140680%5bDISCUI%5d&filter=method%3A2%5F18" target="_blank">Mutation scanning of select exons (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C1140680%5bDISCUI%5d&filter=method%3A2%5F17" target="_blank">Mutation scanning of the entire coding region (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C1140680%5bDISCUI%5d&filter=method%3A2%5F9" target="_blank">Sequence analysis of select exons (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C1140680%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (23)</a></li>
|
||
<li><a href="/gtr/tests?term=C1140680%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (13)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C1140680%5bDISCUI%5d" target="_blank">See all (38)</a></total></li>
|
||
</ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_119">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=167000" target="_blank">OMIM</a></li><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=213500" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Ovarian%20cancer" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_121">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22ovarian%20cancer%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Ovarian%20cancer%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/ovarian.pdf">NCCN, 2024</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024</div></li><li><a target="_blank" href="https://www.nice.org.uk/guidance/cg122">NICE, 2023</a><div>UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023</div></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_115">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Molecular_resources">Molecular resources</h1><a sid="115" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=116806%20164730%20164870%20171834%20192090%20600632%20602544" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=207[geneid]" target="_blank">View AKT1 variations in ClinVar</a></li><li><a href="/clinvar/?term=999[geneid]" target="_blank">View CDH1 variations in ClinVar</a></li><li><a href="/clinvar/?term=1499[geneid]" target="_blank">View CTNNB1 variations in ClinVar</a></li><li><a href="/clinvar/?term=2064[geneid]" target="_blank">View ERBB2 variations in ClinVar</a></li><li><a href="/clinvar/?term=4978[geneid]" target="_blank">View OPCML variations in ClinVar</a></li><li><a href="/clinvar/?term=5071[geneid]" target="_blank">View PRKN variations in ClinVar</a></li><li><a href="/clinvar/?term=5290[geneid]" target="_blank">View PIK3CA variations in ClinVar</a></li><li><a href="/nuccore/171906587,190341080,194440663,237858736,237858742,237874257,262072976" target="_blank">RefSeqGene</a></li><li><a href="https://catalog.coriell.org/Search?q=167000" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_116">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Consumer_resources">Consumer resources</h1><a sid="116" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="https://www.malacards.org/card/ovarian_cancer" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Ovarian%20cancer" target="_blank">MedlinePlus</a></li><li><a href="https://medlineplus.gov/genetics/condition/ovarian-cancer" target="_blank">MedlinePlusGenetics (GHR)</a></li><li><a href="https://rarediseases.info.nih.gov/diseases/7295/disease" target="_blank">NCATS Office of Rare Diseases Research (GARD)</a></li></ul></div>
|
||
</div>
|
||
</div>
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Reviews</h3>
|
||
</div>
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