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<meta name="keywords" content="C0398623, blood hyperviscosity, disease or syndrome, excessive blood clotting, hypercoagulabilities, hypercoagulability, hypercoagulability state, hypercoagulable, hypercoagulable state, non rare in europe: non rare thrombophilia, thrombophilia, thrombophilias, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="An abnormality of coagulation associated with an increased risk of thrombosis." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=98306
|
||
ConceptID=C0398623
|
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-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Hypercoagulability</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98306</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0398623</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Thrombophilia</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Hypercoagulability state (76612001); Hypercoagulable state (76612001); Hypercoagulability (76612001); Thrombophilia (234467004)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0100724">HP:0100724</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0002305" target="_blank">MONDO:0002305</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=64738">ORPHA64738</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">An abnormality of coagulation associated with an increased risk of thrombosis. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
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||
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||
<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0398623[DISCUI]&test_type=Clinical" ref="ncbi_uid=98306">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=98306" ref="ncbi_uid=98306">V</a></span></span><span class="TLline">Hypercoagulability</span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C2584620[DISCUI]&test_type=Clinical" ref="ncbi_uid=391721">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/391721" ref="tree=GTR&ncbi_uid=391721&link_uid=391721" title="View MedGen record for 'Hereditary thrombophilia'">Hereditary thrombophilia</a></span></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/163092" ref="tree=MeSH" title="MedGen record for Abnormality of blood and blood-forming tissues">Abnormality of blood and blood-forming tissues</a></span><ul><li><span class="TLline"><a href="/medgen/375979" ref="tree=MeSH" title="MedGen record for Abnormality of coagulation">Abnormality of coagulation</a></span><ul><li><span class="matched_ds">Hypercoagulability</span><ul><li><span class="TLline"><a href="/medgen/41620" ref="tree=MeSH" title="MedGen record for Disseminated intravascular coagulation">Disseminated intravascular coagulation</a></span><ul><li><span class="TLline"><a href="/medgen/868744" ref="tree=MeSH" title="MedGen record for Acute disseminated intravascular coagulation">Acute disseminated intravascular coagulation</a></span></li><li><span class="TLline"><a href="/medgen/354681" ref="tree=MeSH" title="MedGen record for Chronic disseminated intravascular coagulation">Chronic disseminated intravascular coagulation</a></span></li><li><span class="TLline"><a href="/medgen/510687" ref="tree=MeSH" title="MedGen record for Disseminated intravascular coagulation in newborn">Disseminated intravascular coagulation in newborn</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/75781" ref="tree=MeSH" title="MedGen record for Hereditary antithrombin deficiency">Hereditary antithrombin deficiency</a></span></li><li><span class="TLline"><a href="/medgen/391721" ref="tree=MeSH" title="MedGen record for Hereditary thrombophilia">Hereditary thrombophilia</a></span><ul><li><span class="TLline"><a href="/medgen/416465" ref="tree=MeSH" title="MedGen record for Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency">Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency</a></span></li><li><span class="TLline"><a href="/medgen/671121" ref="tree=MeSH" title="MedGen record for Hereditary thrombophilia due to congenital protein C deficiency">Hereditary thrombophilia due to congenital protein C deficiency</a></span></li><li><span class="TLline"><a href="/medgen/748876" ref="tree=MeSH" title="MedGen record for Hereditary thrombophilia due to congenital protein S deficiency">Hereditary thrombophilia due to congenital protein S deficiency</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/69229" ref="tree=MeSH" title="MedGen record for Protein S deficiency disease">Protein S deficiency disease</a></span></li><li><span class="TLline"><a href="/medgen/96016" ref="tree=MeSH" title="MedGen record for Reduced protein C activity">Reduced protein C activity</a></span></li><li><span class="TLline"><a href="/medgen/109068" ref="tree=MeSH" title="MedGen record for Resistance to activated protein C">Resistance to activated protein C</a></span></li><li><span class="TLline"><a href="/medgen/48266" ref="tree=MeSH" title="MedGen record for Thrombotic thrombocytopenic purpura">Thrombotic thrombocytopenic purpura</a></span><ul><li><span class="TLline"><a href="/medgen/391723" ref="tree=MeSH" title="MedGen record for Acquired thrombotic thrombocytopenic purpura">Acquired thrombotic thrombocytopenic purpura</a></span></li><li><span class="TLline"><a href="/medgen/224783" ref="tree=MeSH" title="MedGen record for Upshaw-Schulman syndrome">Upshaw-Schulman syndrome</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_396074"><div><strong>Thrombophilia due to activated protein C resistance</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>396074</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1861171</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Factor V Leiden thrombophilia is characterized by venous thromboembolism (VTE) manifesting most commonly in adults as deep vein thrombosis (DVT) in the legs or pulmonary embolism. Thrombosis in unusual locations is less common. Factors that predispose to VTE in factor V Leiden thrombophilia include: the number of factor V Leiden variant alleles (homozygotes have a much greater thrombotic risk); family history of VTE; presence of coexisting genetic thrombophilic disorders; acquired thrombophilic disorders (e.g., antiphospholipid antibody syndrome, paroxysmal nocturnal hemoglobinuria, myeloproliferative disorders); and circumstantial risk factors (e.g., pregnancy, malignancy, central venous catheters, travel, combined oral contraceptive use and other combined contraceptives, oral hormone replacement therapy [HRT], obesity, leg injury, and advancing age).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/396074">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_436138"><div><strong>Thrombophilia due to protein C deficiency, autosomal dominant</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>436138</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2674321</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Heterozygous protein C deficiency is characterized by recurrent venous thrombosis. However, many adults with heterozygous disease may be asymptomatic (Millar et al., 2000). Individuals with decreased amounts of protein C are classically referred to as having type I deficiency and those with normal amounts of a functionally defective protein as having type II deficiency (Bertina et al., 1984). Acquired protein C deficiency is a clinically similar disorder caused by development of an antibody against protein C. Clouse and Comp (1986) reviewed the structural and functional properties of protein C and discussed both hereditary and acquired deficiency of protein C.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/436138">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_394120"><div><strong>Thrombophilia due to protein C deficiency, autosomal recessive</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>394120</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2676759</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal recessive protein C deficiency resulting from homozygous or compound heterozygous PROC mutations is a thrombotic condition that can manifest as a severe neonatal disorder or as a milder disorder with late-onset thrombophilia (Millar et al., 2000).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/394120">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_411730"><div><strong>Thrombophilia, X-linked, due to factor 9 defect</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>411730</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2749016</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A hemostatic disorder characterized by a tendency to thrombosis that has X-linked recessive inheritance, and can be caused by a gain-of-function mutation in the gene encoding factor IX (F9).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/411730">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_416465"><div><strong>Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>416465</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2751090</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency is a rare, genetic, coagulation disorder characterized by a tendency to develop thrombosis, resulting from decreased histidine-rich glycoprotein (HRG) plasma levels. Manifestations are variable depending on location of thrombosis, but may include headaches, diplopia, progressive pain, limb swelling, itching or ulceration, and brownish skin discoloration, among others.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/416465">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_479841"><div><strong>Thrombophilia due to protein S deficiency, autosomal dominant</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>479841</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3278211</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Heterozygous protein S deficiency, like protein C deficiency (176860), is characterized by recurrent venous thrombosis. Bertina (1990) classified protein S deficiency into 3 clinical subtypes based on laboratory findings. Type I refers to deficiency of both free and total protein S as well as decreased protein S activity; type II shows normal plasma values, but decreased protein S activity; and type III shows decreased free protein S levels and activity, but normal total protein S levels. Approximately 40% of protein S circulates as a free active form, whereas the remaining 60% circulates as an inactive form bound to C4BPA (120830). Zoller et al. (1995) observed coexistence of type I and type III PROS1-deficient phenotypes within a single family and determined that the subtypes are allelic. Under normal conditions, the concentration of protein S exceeds that of C4BPA by approximately 30 to 40%. Thus, free protein S is the molar surplus of protein S over C4BPA. Mild protein S deficiency will thus present with selective deficiency of free protein S, whereas more pronounced protein S deficiency will also decrease the complexed protein S and consequently the total protein S level. These findings explained why assays for free protein S have a higher predictive value for protein S deficiency. See also autosomal recessive thrombophilia due to protein S deficiency (THPH6; 614514), which is a more severe disorder.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/479841">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_482606"><div><strong>Thrombomodulin-related bleeding disorder</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>482606</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3280976</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The role of thrombomodulin in thrombosis is controversial. Although there have been several reports of THBD mutations in patients with venous thrombosis, clear functional evidence for the pathogenicity of these mutations is lacking. In a review, Anastasiou et al. (2012) noted that thrombomodulin has a major role in capillary beds and that THBD variation may not be associated with large vessel thrombosis. It is likely that genetic or environmental risk factors in addition to THBD variation are involved in the pathogenesis of venous thrombosis. However, variation in the THBD gene may be associated with increased risk for arterial thrombosis and myocardial infarction. This association may be attributed to the fact that thrombomodulin can modulate inflammatory processes, complement activity, and fibrinolysis.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/482606">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_482722"><div><strong>Thrombophilia due to protein S deficiency, autosomal recessive</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>482722</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3281092</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal recessive thrombophilia due to protein S deficiency is a very rare and severe hematologic disorder resulting in thrombosis and secondary hemorrhage usually beginning in early infancy. Some affected individuals develop neonatal purpura fulminans, multifocal thrombosis, or intracranial hemorrhage (Pung-amritt et al., 1999; Fischer et al., 2010), whereas others have recurrent thromboses later in childhood (Comp et al., 1984). See also autosomal dominant thrombophilia due to protein S deficiency (THPH5; 612336), a less severe disorder caused by heterozygous mutation in the PROS1 gene.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/482722">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_416465" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_482606" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Thrombomodulin-related bleeding disorder</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_396074" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Thrombophilia due to activated protein C resistance</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_436138" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Thrombophilia due to protein C deficiency, autosomal dominant</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_394120" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Thrombophilia due to protein C deficiency, autosomal recessive</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_479841" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Thrombophilia due to protein S deficiency, autosomal dominant</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_482722" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Thrombophilia due to protein S deficiency, autosomal recessive</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_411730" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Thrombophilia, X-linked, due to factor 9 defect</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35149395">Management of venous thromboembolism in pregnancy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kalaitzopoulos DR,
|
||
Panagopoulos A,
|
||
Samant S,
|
||
Ghalib N,
|
||
Kadillari J,
|
||
Daniilidis A,
|
||
Samartzis N,
|
||
Makadia J,
|
||
Palaiodimos L,
|
||
Kokkinidis DG,
|
||
Spyrou N</span><br />
|
||
<span class="medgenPMjournal">Thromb Res</span>
|
||
2022 Mar;211:106-113.
|
||
Epub 2022 Feb 7
|
||
doi: 10.1016/j.thromres.2022.02.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35149395" target="_blank">35149395</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34228062">Diagnosis and Management of Infertility: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Carson SA,
|
||
Kallen AN</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2021 Jul 6;326(1):65-76.
|
||
doi: 10.1001/jama.2021.4788.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34228062" target="_blank">34228062</a><a href="/pmc/articles/PMC9302705" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33143632">Herbal Medicines for Diabetes Management and its Secondary Complications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kumar S,
|
||
Mittal A,
|
||
Babu D,
|
||
Mittal A</span><br />
|
||
<span class="medgenPMjournal">Curr Diabetes Rev</span>
|
||
2021;17(4):437-456.
|
||
doi: 10.2174/1573399816666201103143225.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33143632" target="_blank">33143632</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22hypercoagulability%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (201)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36410400">Thrombosis in Pregnant Women with Hemolytic Anemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Papadakis E,
|
||
Brenner B</span><br />
|
||
<span class="medgenPMjournal">Semin Thromb Hemost</span>
|
||
2023 Jun;49(4):364-370.
|
||
Epub 2022 Nov 21
|
||
doi: 10.1055/s-0042-1758819.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36410400" target="_blank">36410400</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34000740">The Pathophysiology of Hypercoagulability and Infertility.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Malinowski AK</span><br />
|
||
<span class="medgenPMjournal">Semin Reprod Med</span>
|
||
2021 Mar;39(1-02):34-61.
|
||
Epub 2021 May 17
|
||
doi: 10.1055/s-0041-1729763.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34000740" target="_blank">34000740</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30470272">Stroke in Pregnancy: An Update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Camargo EC,
|
||
Feske SK,
|
||
Singhal AB</span><br />
|
||
<span class="medgenPMjournal">Neurol Clin</span>
|
||
2019 Feb;37(1):131-148.
|
||
doi: 10.1016/j.ncl.2018.09.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30470272" target="_blank">30470272</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30122183">Hypercoagulability in Pulmonary Hypertension.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bazan IS,
|
||
Fares WH</span><br />
|
||
<span class="medgenPMjournal">Clin Chest Med</span>
|
||
2018 Sep;39(3):595-603.
|
||
doi: 10.1016/j.ccm.2018.04.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30122183" target="_blank">30122183</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28049361">Oral Contraceptives and HRT Risk of Thrombosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gialeraki A,
|
||
Valsami S,
|
||
Pittaras T,
|
||
Panayiotakopoulos G,
|
||
Politou M</span><br />
|
||
<span class="medgenPMjournal">Clin Appl Thromb Hemost</span>
|
||
2018 Mar;24(2):217-225.
|
||
Epub 2017 Jan 4
|
||
doi: 10.1177/1076029616683802.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28049361" target="_blank">28049361</a><a href="/pmc/articles/PMC6714678" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypercoagulability%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2611)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35985703">The Antiphospholipid Syndrome in the Pediatric Population.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sloan EE,
|
||
McCurdy D</span><br />
|
||
<span class="medgenPMjournal">Adv Pediatr</span>
|
||
2022 Aug;69(1):107-121.
|
||
Epub 2022 Jun 21
|
||
doi: 10.1016/j.yapd.2022.03.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35985703" target="_blank">35985703</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32722984">Plantar vein thrombosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Edwards SR,
|
||
Wood OD</span><br />
|
||
<span class="medgenPMjournal">Phlebology</span>
|
||
2021 Feb;36(1):26-31.
|
||
Epub 2020 Jul 28
|
||
doi: 10.1177/0268355520946620.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32722984" target="_blank">32722984</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30122183">Hypercoagulability in Pulmonary Hypertension.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bazan IS,
|
||
Fares WH</span><br />
|
||
<span class="medgenPMjournal">Clin Chest Med</span>
|
||
2018 Sep;39(3):595-603.
|
||
doi: 10.1016/j.ccm.2018.04.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30122183" target="_blank">30122183</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28049361">Oral Contraceptives and HRT Risk of Thrombosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gialeraki A,
|
||
Valsami S,
|
||
Pittaras T,
|
||
Panayiotakopoulos G,
|
||
Politou M</span><br />
|
||
<span class="medgenPMjournal">Clin Appl Thromb Hemost</span>
|
||
2018 Mar;24(2):217-225.
|
||
Epub 2017 Jan 4
|
||
doi: 10.1177/1076029616683802.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28049361" target="_blank">28049361</a><a href="/pmc/articles/PMC6714678" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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|
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<div class="nl"><a target="_blank" href="/pubmed/24365309">Nephrotic syndrome.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Liebeskind DS</span><br />
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|
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<span class="bold">PMID: </span><a href="/pubmed/24365309" target="_blank">24365309</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypercoagulability%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1562)</a></div><h3 class="subhead">Therapy</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/35221084">Clinical Features and Management of COVID-19-Associated Hypercoagulability.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Massaro G,
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Lecis D,
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Martuscelli E,
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Chiricolo G,
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Sangiorgi GM</span><br />
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2022 Mar;14(1):41-52.
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Epub 2021 Oct 30
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<span class="bold">PMID: </span><a href="/pubmed/35221084" target="_blank">35221084</a><a href="/pmc/articles/PMC8556574" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/33706160">The pathogenesis of abnormal uterine bleeding in myopathic uteri.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Turner BM,
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Cramer SF,
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Heller DS</span><br />
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<span class="medgenPMjournal">Ann Diagn Pathol</span>
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2021 Jun;52:151726.
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<span class="bold">PMID: </span><a href="/pubmed/33706160" target="_blank">33706160</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/33089935">Viscoelastic testing in liver transplantation.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Sakai T</span><br />
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2020 Oct;60 Suppl 6:S61-S69.
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<span class="bold">PMID: </span><a href="/pubmed/33089935" target="_blank">33089935</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28181217">Hypercoagulability and Migraine.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Tietjen GE,
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<span class="medgenPMjournal">Headache</span>
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2018 Jan;58(1):173-183.
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<span class="bold">PMID: </span><a href="/pubmed/28181217" target="_blank">28181217</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28049361">Oral Contraceptives and HRT Risk of Thrombosis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gialeraki A,
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Pittaras T,
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Panayiotakopoulos G,
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2018 Mar;24(2):217-225.
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<span class="bold">PMID: </span><a href="/pubmed/28049361" target="_blank">28049361</a><a href="/pmc/articles/PMC6714678" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypercoagulability%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1608)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37024364">Stroke and cancer.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Zuber M</span><br />
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2023 Jun;179(5):417-424.
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<span class="bold">PMID: </span><a href="/pubmed/37024364" target="_blank">37024364</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/36117463">To Clot or Not to Clot: Deepening Our Understanding of Alterations in the Hemostatic System.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Reagan WJ,
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Brooks MB,
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Grozovsky R,
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Pittman D,
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Vitsky A,
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Brenneman K</span><br />
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<span class="medgenPMjournal">Toxicol Pathol</span>
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2022 Oct;50(7):890-894.
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Epub 2022 Sep 17
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doi: 10.1177/01926233221125172.
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<span class="bold">PMID: </span><a href="/pubmed/36117463" target="_blank">36117463</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/35961476">Venous thromboembolism in cancer and cancer immunotherapy.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kacimi SEO,
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Moeinafshar A,
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Haghighi SS,
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Saghazadeh A,
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Rezaei N</span><br />
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<span class="medgenPMjournal">Crit Rev Oncol Hematol</span>
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2022 Oct;178:103782.
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Epub 2022 Aug 10
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doi: 10.1016/j.critrevonc.2022.103782.
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<span class="bold">PMID: </span><a href="/pubmed/35961476" target="_blank">35961476</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/33074732">COVID-19 and Hypercoagulability: A Review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kichloo A,
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Dettloff K,
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Aljadah M,
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Jamal S,
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Singh J,
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Kumar A,
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<span class="bold">PMID: </span><a href="/pubmed/33074732" target="_blank">33074732</a><a href="/pmc/articles/PMC7592310" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/19654481">The link between cancer and venous thromboembolism: a review.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypercoagulability%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1042)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37024364">Stroke and cancer.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Zuber M</span><br />
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<span class="medgenPMjournal">Rev Neurol (Paris)</span>
|
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2023 Jun;179(5):417-424.
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Epub 2023 Apr 4
|
||
doi: 10.1016/j.neurol.2023.03.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37024364" target="_blank">37024364</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36117463">To Clot or Not to Clot: Deepening Our Understanding of Alterations in the Hemostatic System.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reagan WJ,
|
||
Brooks MB,
|
||
Grozovsky R,
|
||
Pittman D,
|
||
Vitsky A,
|
||
Brenneman K</span><br />
|
||
<span class="medgenPMjournal">Toxicol Pathol</span>
|
||
2022 Oct;50(7):890-894.
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||
Epub 2022 Sep 17
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doi: 10.1177/01926233221125172.
|
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<span class="bold">PMID: </span><a href="/pubmed/36117463" target="_blank">36117463</a></div>
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||
|
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<div class="nl"><a target="_blank" href="/pubmed/29904875">Frequency and clinical implications of hypercoagulability states in a cohort of patients with migraine with aura.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Cecchi G,
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Paolucci M,
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Ulivi M,
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Assenza F,
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Brunelli N,
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Cascio Rizzo A,
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Altamura C,
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<span class="bold">PMID: </span><a href="/pubmed/29904875" target="_blank">29904875</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/17336687">The antiphospholipid syndrome.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Fischer MJ,
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<span class="medgenPMjournal">Semin Nephrol</span>
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<div class="nl"><a target="_blank" href="/pubmed/16860994">Hemostasis and aging.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Franchini M</span><br />
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypercoagulability%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1274)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/35468241">What is the optimal prophylaxis against postoperative deep vein thrombosis in the living donor to avoid complications and enhance recovery? - A systematic review of the literature and expert panel recommendations.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ruffolo LI,
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Levstik M,
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Boehly J,
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Spiro M,
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||
Raptis DA,
|
||
Liu L,
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||
Hernandez-Alejandro R;
|
||
ERAS4OLT.org Working Group</span><br />
|
||
<span class="medgenPMjournal">Clin Transplant</span>
|
||
2022 Oct;36(10):e14688.
|
||
doi: 10.1111/ctr.14688.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35468241" target="_blank">35468241</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32551814">Coagulation Dysfunction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fei Y,
|
||
Tang N,
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||
Liu H,
|
||
Cao W</span><br />
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<span class="medgenPMjournal">Arch Pathol Lab Med</span>
|
||
2020 Oct 1;144(10):1223-1229.
|
||
doi: 10.5858/arpa.2020-0324-SA.
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||
<span class="bold">PMID: </span><a href="/pubmed/32551814" target="_blank">32551814</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32282949">Hematological findings and complications of COVID-19.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Terpos E,
|
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Ntanasis-Stathopoulos I,
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Elalamy I,
|
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Kastritis E,
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||
Sergentanis TN,
|
||
Politou M,
|
||
Psaltopoulou T,
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Gerotziafas G,
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Dimopoulos MA</span><br />
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<span class="medgenPMjournal">Am J Hematol</span>
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2020 Jul;95(7):834-847.
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||
Epub 2020 May 23
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||
doi: 10.1002/ajh.25829.
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<span class="bold">PMID: </span><a href="/pubmed/32282949" target="_blank">32282949</a><a href="/pmc/articles/PMC7262337" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28395787">Testing for thrombophilia in mesenteric venous thrombosis - Retrospective original study and systematic review.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Zarrouk M,
|
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Salim S,
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Elf J,
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Gottsäter A,
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Acosta S</span><br />
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<span class="medgenPMjournal">Best Pract Res Clin Gastroenterol</span>
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2017 Feb;31(1):39-48.
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Epub 2017 Jan 4
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||
doi: 10.1016/j.bpg.2016.11.002.
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||
<span class="bold">PMID: </span><a href="/pubmed/28395787" target="_blank">28395787</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25261079">Effect of thromboelastography (TEG®) and rotational thromboelastometry (ROTEM®) on diagnosis of coagulopathy, transfusion guidance and mortality in trauma: descriptive systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Da Luz LT,
|
||
Nascimento B,
|
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Shankarakutty AK,
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Adhikari NK</span><br />
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<span class="medgenPMjournal">Crit Care</span>
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2014 Sep 27;18(5):518.
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<span class="bold">PMID: </span><a href="/pubmed/25261079" target="_blank">25261079</a><a href="/pmc/articles/PMC4206701" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypercoagulability%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (83)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
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|
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|
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|
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|
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<div class="supplemental col three_col last">
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0398623%5bDISCUI%5d&filter=method%3A1%5F1" target="_blank">Analyte (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0398623%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (17)</a></li>
|
||
<li><a href="/gtr/tests?term=C0398623%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (19)</a></li>
|
||
<li><a href="/gtr/tests?term=C0398623%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (26)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0398623%5bDISCUI%5d" target="_blank">See all (46)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=64738" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Thrombophilia" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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