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<meta name="keywords" content="C0346180, malignant germ cell neoplasm of ovary, malignant germ cell neoplasm of the ovary, malignant germ cell tumor of ovary, malignant germ cell tumor of the ovary, malignant germ cell tumour of the ovary, malignant ovarian germ cell neoplasm, malignant ovarian germ cell tumor, malignant ovarian germ cell tumour, mogct, neoplastic process, ovarian germ cell cancer, ovary malignant germ cell tumor, ovary malignant germ cell tumour, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Ovarian germ cell cancers are malignancies that arise from germ cells of the embryonic gonad. Although benign germ cell tumors are relatively common, accounting for approximately 20% of all ovarian neoplasms, malignant ovarian germ cell tumors are rare. Weiss et al. (1977) estimated that less than 5% of ovarian cancers are of germ cell origin." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=87544
|
||
ConceptID=C0346180
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Malignant germ cell tumor of ovary</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>87544</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0346180</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Ovarian germ cell cancer</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Malignant germ cell tumor of ovary (254869000)</td></tr>
|
||
<tr><td>Modes of inheritance:</td>
|
||
<td>
|
||
<div class="divPopper rprt" id="moi_989040"><div><strong>Unknown inheritance</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>989040</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier assigned by MedGen (starting with CN) for terms that cannot be identified in NLM's Unified Medical Language system (UMLS) Click for more information.">CN307042</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Source: Orphanet</div>
|
||
<div class="spaceAbove">Hereditary clinical entity whose mode of inheritance is unknown.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/989040">This record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_989040" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Unknown inheritance</a><span> (Orphanet)</span></div></td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0018171" target="_blank">MONDO:0018171</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/603737" target="_blank">603737</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=35807">ORPHA35807</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Ovarian germ cell cancers are malignancies that arise from germ cells of the embryonic gonad. Although benign germ cell tumors are relatively common, accounting for approximately 20% of all ovarian neoplasms, malignant ovarian germ cell tumors are rare. Weiss et al. (1977) estimated that less than 5% of ovarian cancers are of germ cell origin. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=87544" target="_blank" href="/omim/603737">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=87544" ref="ncbi_uid=87544">V</a></span></span><span class="TLline">Malignant germ cell tumor of ovary</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/99182" ref="tree=MeSH" title="MedGen record for Neoplasm by Morphology">Neoplasm by Morphology</a></span><ul><li><span class="TLline"><a href="/medgen/60030" ref="tree=MeSH" title="MedGen record for Germ cell tumor">Germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/890580" ref="tree=MeSH" title="MedGen record for Malignant germ cell tumor">Malignant germ cell tumor</a></span><ul><li><span class="matched_ds">Malignant germ cell tumor of ovary</span><ul><li><span class="TLline"><a href="/medgen/164003" ref="tree=MeSH" title="MedGen record for Childhood Malignant Ovarian Germ Cell Tumor">Childhood Malignant Ovarian Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/234135" ref="tree=MeSH" title="MedGen record for Childhood choriocarcinoma of the ovary">Childhood choriocarcinoma of the ovary</a></span></li><li><span class="TLline"><a href="/medgen/232352" ref="tree=MeSH" title="MedGen record for Childhood ovarian embryonal carcinoma">Childhood ovarian embryonal carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/896650" ref="tree=MeSH" title="MedGen record for Childhood Ovarian Mixed Germ Cell Tumor">Childhood Ovarian Mixed Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/234136" ref="tree=MeSH" title="MedGen record for Childhood ovarian yolk sac tumor">Childhood ovarian yolk sac tumor</a></span></li><li><span class="TLline"><a href="/medgen/272465" ref="tree=MeSH" title="MedGen record for Pediatric ovarian dysgerminoma">Pediatric ovarian dysgerminoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/798473" ref="tree=MeSH" title="MedGen record for Malignant dysgerminomatous germ cell tumor of ovary">Malignant dysgerminomatous germ cell tumor of ovary</a></span></li><li><span class="TLline"><a href="/medgen/1826164" ref="tree=MeSH" title="MedGen record for Malignant non-dysgerminomatous germ cell tumor of ovary">Malignant non-dysgerminomatous germ cell tumor of ovary</a></span></li><li><span class="TLline"><a href="/medgen/1657209" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Teratoma">Malignant Ovarian Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/137777" ref="tree=MeSH" title="MedGen record for Malignant struma ovarii">Malignant struma ovarii</a></span></li><li><span class="TLline"><a href="/medgen/275291" ref="tree=MeSH" title="MedGen record for Ovarian primitive germ cell tumor">Ovarian primitive germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/83414" ref="tree=MeSH" title="MedGen record for Dysgerminoma of ovary">Dysgerminoma of ovary</a></span><ul><li><span class="TLline"><a href="/medgen/1661411" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Dysgerminoma AJCC v6 and v7">Stage I Ovarian Dysgerminoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1670106" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Dysgerminoma AJCC v6 and v7">Stage II Ovarian Dysgerminoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1669220" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Dysgerminoma AJCC v6 and v7">Stage III Ovarian Dysgerminoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1665964" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Dysgerminoma AJCC v6 and v7">Stage IV Ovarian Dysgerminoma AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83602" ref="tree=MeSH" title="MedGen record for Ovarian mixed germ cell neoplasm">Ovarian mixed germ cell neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/769623" ref="tree=MeSH" title="MedGen record for Ovarian Non-Dysgerminomatous Germ Cell Tumor">Ovarian Non-Dysgerminomatous Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/274798" ref="tree=MeSH" title="MedGen record for Non-gestational ovarian choriocarcinoma">Non-gestational ovarian choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/91090" ref="tree=MeSH" title="MedGen record for Ovarian embryonal carcinoma">Ovarian embryonal carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/83415" ref="tree=MeSH" title="MedGen record for Ovarian yolk sac tumor">Ovarian yolk sac tumor</a></span></li><li><span class="TLline"><a href="/medgen/271323" ref="tree=MeSH" title="MedGen record for Polyembryoma of the ovary">Polyembryoma of the ovary</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/906353" ref="tree=MeSH" title="MedGen record for Primary non-gestational choriocarcinoma of ovary">Primary non-gestational choriocarcinoma of ovary</a></span></li><li><span class="TLline"><a href="/medgen/79058" ref="tree=MeSH" title="MedGen record for Recurrent Ovarian Germ Cell Tumor">Recurrent Ovarian Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/124681" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Germ Cell Tumor AJCC v6 and v7">Stage I Ovarian Germ Cell Tumor AJCC v6 and v7</a></span><ul><li><span class="TLline"><a href="/medgen/277761" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234359" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Polyembryoma AJCC v6 and v7">Stage I Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1656269" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Teratoma AJCC v6 and v7">Stage I Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277762" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236856" ref="tree=MeSH" title="MedGen record for Stage IA Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IA Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277680" ref="tree=MeSH" title="MedGen record for Stage IB Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IB Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236865" ref="tree=MeSH" title="MedGen record for Stage IC Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IC Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/76052" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Germ Cell Tumor AJCC v6 and v7">Stage II Ovarian Germ Cell Tumor AJCC v6 and v7</a></span><ul><li><span class="TLline"><a href="/medgen/236906" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236907" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Polyembryoma AJCC v6 and v7">Stage II Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1663837" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Teratoma AJCC v6 and v7">Stage II Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234856" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277689" ref="tree=MeSH" title="MedGen record for Stage IIA Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIA Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277695" ref="tree=MeSH" title="MedGen record for Stage IIB Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIB Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/233492" ref="tree=MeSH" title="MedGen record for Stage IIC Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIC Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124682" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Germ Cell Tumor AJCC v6 and v7">Stage III Ovarian Germ Cell Tumor AJCC v6 and v7</a></span><ul><li><span class="TLline"><a href="/medgen/236896" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277714" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Polyembryoma AJCC v6 and v7">Stage III Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1648756" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Teratoma AJCC v6 and v7">Stage III Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236897" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234840" ref="tree=MeSH" title="MedGen record for Stage IIIA Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIIA Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236887" ref="tree=MeSH" title="MedGen record for Stage IIIB Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIIB Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/233497" ref="tree=MeSH" title="MedGen record for Stage IIIC Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IIIC Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1669130" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IV Ovarian Germ Cell Tumor AJCC v6 and v7</a></span><ul><li><span class="TLline"><a href="/medgen/234888" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234889" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Polyembryoma AJCC v6 and v7">Stage IV Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1661846" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Teratoma AJCC v6 and v7">Stage IV Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234890" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=10400&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Malignant germ cell tumor of ovary</span> in Orphanet.</div></div></div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/32615119">ESGO-SIOPE guidelines for the management of adolescents and young adults with non-epithelial ovarian cancers.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Sessa C,
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Schneider DT,
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Planchamp F,
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Baust K,
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Braicu EI,
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Concin N,
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Godzinski J,
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McCluggage WG,
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Orbach D,
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Pautier P,
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Peccatori FA,
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Morice P,
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Calaminus G</span><br />
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<span class="medgenPMjournal">Lancet Oncol</span>
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2020 Jul;21(7):e360-e368.
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doi: 10.1016/S1470-2045(20)30091-7.
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<span class="bold">PMID: </span><a href="/pubmed/32615119" target="_blank">32615119</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/29697741">Non-epithelial ovarian cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ray-Coquard I,
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Morice P,
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Lorusso D,
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Prat J,
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Oaknin A,
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Pautier P,
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Colombo N;
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ESMO Guidelines Committee</span><br />
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<span class="medgenPMjournal">Ann Oncol</span>
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2018 Oct 1;29(Suppl 4):iv1-iv18.
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doi: 10.1093/annonc/mdy001.
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<span class="bold">PMID: </span><a href="/pubmed/29697741" target="_blank">29697741</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/6362873">The diagnosis and treatment of yolk sac tumors in infants and children.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Green DM</span><br />
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<span class="medgenPMjournal">Cancer Treat Rev</span>
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1983 Dec;10(4):265-88.
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doi: 10.1016/0305-7372(83)90014-2.
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<span class="bold">PMID: </span><a href="/pubmed/6362873" target="_blank">6362873</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(malignant%20germ%20cell%20tumor%20of%20ovary)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (129)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/ovarian.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024</a></h3>
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<h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/cg122" target="_blank">UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023</a></h3>
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</div>
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</div>
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<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
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to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></div></div></div></div></div></div></div>
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div>
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<!-- MedGen supplemental column starts here -->
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=603737" target="_blank">OMIM</a></li><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=35807" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Malignant%20germ%20cell%20tumor%20of%20ovary" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(malignant%20germ%20cell%20tumor%20of%20ovary)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Malignant%20germ%20cell%20tumor%20of%20ovary%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/ovarian.pdf">NCCN, 2024</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024</div></li><li><a target="_blank" href="https://www.nice.org.uk/guidance/cg122">NICE, 2023</a><div>UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023</div></li></ul></div>
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