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<meta name="keywords" content="C0339573, chronic primary open angle glaucoma, chronic simple glaucoma, coag - chronic open-angle glaucoma, csg - chronic simple glaucoma, disease or syndrome, glaucoma 1, open angle, e, glaucoma, primary open angle, optn, optn-related open angle glaucoma, poag, poag - primary open-angle glaucoma, primary open angle glaucoma, primary open-angle glaucoma, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Quigley (1993) reviewed adult-onset primary open angle glaucoma, which combines a particular abnormal appearance of the optic disc (optic nerve head) with a slowly progressive loss of visual sensitivity. Many patients with glaucoma have intraocular pressures above the normal range, although this cannot be considered part of the definition of the disease, since some patients have normal intraocular pressures. Changes in the optic disc, either inherited or acquired, contribute to the development of the disorder, which leads to visual loss from increasing nerve fiber layer atrophy. Quigley et al. (1994) stated that POAG should be reviewed as a multifactorial disorder. Genetic Heterogeneity of Primary Open Angle Glaucoma Other forms of primary open angle glaucoma include GLC1A (137750), caused by mutation in the MYOC gene (601652) on chromosome 1q24; GLC1B (606689) on chromosome 2cen-q13; GLC1C (601682) on chromosome 3q21-q24; GLC1D (602429) on chromosome 8q23; GLC1F (603383), caused by mutation in the ASB10 gene (615054) on chromosome 7q36; GLC1G (609887), caused by mutation in the WDR36 gene (609669) on chromosome 5q22; GLC1H (611276), caused by mutation in the EFEMP1 gene (601548) on chromosome 2p16; GLC1I (609745) on chromosome 15q11-q13; GLC1J (608695) on chromosome 9q22; GLC1K (608696) on chromosome 20p12; GLC1L (see 137750) on chromosome 3p22-p21; GLC1M (610535) on chromosome 5q22; GLC1N (611274) on chromosome 15q22-q24; GLC1O (613100), caused by mutation in the NTF4 gene (162662) on chromosome 19q13; GLC1P (177700), caused by an approximately 300-kb duplication on chromosome 12q24, most likely involving the TBK1 gene (604834). Nail-patella syndrome (NPS; 161200), which is caused by mutation in the LMX1B gene (602575) on chromosome 9q34, has open angle glaucoma as a pleiotropic feature. Other Forms of Glaucoma For a general description and a discussion of genetic heterogeneity of congenital forms of glaucoma, see GLC3A (231300). See 606657 for a discussion of normal tension glaucoma (NTG) or normal pressure glaucoma (NPG), a subtype of POAG. See 618880 for a discussion of primary closed-angle glaucoma." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=87389
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ConceptID=C0339573
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Primary open angle glaucoma<span class="h1sub">(POAG)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>87389</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0339573</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>OPTN-related open angle glaucoma; POAG</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Primary open angle glaucoma (77075001); Chronic simple glaucoma (77075001); Primary open-angle glaucoma (77075001); COAG - chronic open-angle glaucoma (77075001); CSG - chronic simple glaucoma (77075001); POAG - primary open-angle glaucoma (77075001)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="OPTN - ID: 10133 - NCBI Gene" href="/gene/10133" class="medgenPMinfo">OPTN</a> (10p13)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0100553" target="_blank">MONDO:0100553</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/137760" target="_blank">137760</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Quigley (1993) reviewed adult-onset primary open angle glaucoma, which combines a particular abnormal appearance of the optic disc (optic nerve head) with a slowly progressive loss of visual sensitivity. Many patients with glaucoma have intraocular pressures above the normal range, although this cannot be considered part of the definition of the disease, since some patients have normal intraocular pressures. Changes in the optic disc, either inherited or acquired, contribute to the development of the disorder, which leads to visual loss from increasing nerve fiber layer atrophy. Quigley et al. (1994) stated that POAG should be reviewed as a multifactorial disorder. Genetic Heterogeneity of Primary Open Angle Glaucoma Other forms of primary open angle glaucoma include GLC1A (137750), caused by mutation in the MYOC gene (601652) on chromosome 1q24; GLC1B (606689) on chromosome 2cen-q13; GLC1C (601682) on chromosome 3q21-q24; GLC1D (602429) on chromosome 8q23; GLC1F (603383), caused by mutation in the ASB10 gene (615054) on chromosome 7q36; GLC1G (609887), caused by mutation in the WDR36 gene (609669) on chromosome 5q22; GLC1H (611276), caused by mutation in the EFEMP1 gene (601548) on chromosome 2p16; GLC1I (609745) on chromosome 15q11-q13; GLC1J (608695) on chromosome 9q22; GLC1K (608696) on chromosome 20p12; GLC1L (see 137750) on chromosome 3p22-p21; GLC1M (610535) on chromosome 5q22; GLC1N (611274) on chromosome 15q22-q24; GLC1O (613100), caused by mutation in the NTF4 gene (162662) on chromosome 19q13; GLC1P (177700), caused by an approximately 300-kb duplication on chromosome 12q24, most likely involving the TBK1 gene (604834). Nail-patella syndrome (NPS; 161200), which is caused by mutation in the LMX1B gene (602575) on chromosome 9q34, has open angle glaucoma as a pleiotropic feature. Other Forms of Glaucoma For a general description and a discussion of genetic heterogeneity of congenital forms of glaucoma, see GLC3A (231300). See 606657 for a discussion of normal tension glaucoma (NTG) or normal pressure glaucoma (NPG), a subtype of POAG. See 618880 for a discussion of primary closed-angle glaucoma. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_6611"><div><strong>Open-angle glaucoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>6611</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0017612</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A type of glaucoma defined by an open, normal appearing anterior chamber angle and raised intraocular pressure,</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/6611">Feature record</a> | <a href="/medgen?term=%22Open-angle%20glaucoma%22%5BClinical%20Features%5D%20OR%206611%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_44558"><div><strong>Myopia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>44558</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0027092</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Nearsightedness, also known as myopia, is an eye condition that causes blurry distance vision. People who are nearsighted have more trouble seeing things that are far away (such as when driving) than things that are close up (such as when reading or using a computer). If it is not treated with corrective lenses or surgery, nearsightedness can lead to squinting, eyestrain, headaches, and significant visual impairment.\n\nNearsightedness usually begins in childhood or adolescence. It tends to worsen with age until adulthood, when it may stop getting worse (stabilize). In some people, nearsightedness improves in later adulthood.\n\nFor normal vision, light passes through the clear cornea at the front of the eye and is focused by the lens onto the surface of the retina, which is the lining of the back of the eye that contains light-sensing cells. People who are nearsighted typically have eyeballs that are too long from front to back. As a result, light entering the eye is focused too far forward, in front of the retina instead of on its surface. It is this change that causes distant objects to appear blurry. The longer the eyeball is, the farther forward light rays will be focused and the more severely nearsighted a person will be.\n\nNearsightedness is measured by how powerful a lens must be to correct it. The standard unit of lens power is called a diopter. Negative (minus) powered lenses are used to correct nearsightedness. The more severe a person's nearsightedness, the larger the number of diopters required for correction. In an individual with nearsightedness, one eye may be more nearsighted than the other.\n\nEye doctors often refer to nearsightedness less than -5 or -6 diopters as "common myopia." Nearsightedness of -6 diopters or more is commonly called "high myopia." This distinction is important because high myopia increases a person's risk of developing other eye problems that can lead to permanent vision loss or blindness. These problems include tearing and detachment of the retina, clouding of the lens (cataract), and an eye disease called glaucoma that is usually related to increased pressure within the eye. The risk of these other eye problems increases with the severity of the nearsightedness. The term "pathological myopia" is used to describe cases in which high myopia leads to tissue damage within the eye.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/44558">Feature record</a> | <a href="/medgen?term=%22Myopia%22%5BClinical%20Features%5D%20OR%2044558%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite"><ul><li><span class="TLline">Abnormality of the eye</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_44558" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Myopia</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_6611" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Open-angle glaucoma</a></span></li></ul></li></ul></div></div>
|
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0017601[DISCUI]&test_type=Clinical" ref="ncbi_uid=42224">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=42224" ref="ncbi_uid=42224">V</a></span></span><span class="TLline"><a href="/medgen/42224" ref="tree=GTR&ncbi_uid=42224&link_uid=42224" title="View MedGen record for 'Glaucoma'">Glaucoma</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1842028[DISCUI]&test_type=Clinical" ref="ncbi_uid=333974">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1842028[DISCUI]&test_type=Research" ref="ncbi_uid=333974">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=333974" target="_blank" href="/omim/137750">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=333974" ref="ncbi_uid=333974">V</a></span></span><span class="TLline"><a href="/medgen/333974" ref="tree=GTR&ncbi_uid=333974&link_uid=333974" title="View MedGen record for 'Glaucoma 1, open angle, A'">Glaucoma 1, open angle, A</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C3887942[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=854650">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=854650" target="_blank" href="/omim/606689">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=854650" ref="ncbi_uid=854650">V</a></span></span><span class="TLline"><a href="/medgen/854650" ref="tree=GTR&ncbi_uid=854650&link_uid=854650" title="View MedGen record for 'Glaucoma 1, open angle, B'">Glaucoma 1, open angle, B</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1865427[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=355468">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=355468" target="_blank" href="/omim/602429">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/355468" ref="tree=GTR&ncbi_uid=355468&link_uid=355468" title="View MedGen record for 'Glaucoma 1, open angle, D'">Glaucoma 1, open angle, D</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1863926[DISCUI]&test_type=Clinical" ref="ncbi_uid=355096">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1863926[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=355096">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=355096" target="_blank" href="/omim/603383">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=355096" ref="ncbi_uid=355096">V</a></span></span><span class="TLline"><a href="/medgen/355096" ref="tree=GTR&ncbi_uid=355096&link_uid=355096" title="View MedGen record for 'Glaucoma 1, open angle, F'">Glaucoma 1, open angle, F</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1835933[DISCUI]&test_type=Clinical" ref="ncbi_uid=332090">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1835933[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=332090">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=332090" target="_blank" href="/omim/609669">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=332090" ref="ncbi_uid=332090">V</a></span></span><span class="TLline"><a href="/medgen/332090" ref="tree=GTR&ncbi_uid=332090&link_uid=332090" title="View MedGen record for 'Glaucoma 1, open angle, G'">Glaucoma 1, open angle, G</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1969811[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=409919">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=409919" target="_blank" href="/omim/601548">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=409919" ref="ncbi_uid=409919">V</a></span></span><span class="TLline"><a href="/medgen/409919" ref="tree=GTR&ncbi_uid=409919&link_uid=409919" title="View MedGen record for 'Glaucoma 1, open angle, H'">Glaucoma 1, open angle, H</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1857852[DISCUI]&test_type=Research" ref="ncbi_uid=341861">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=341861" target="_blank" href="/omim/609745">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/341861" ref="tree=GTR&ncbi_uid=341861&link_uid=341861" title="View MedGen record for 'Glaucoma 1, open angle, I'">Glaucoma 1, open angle, I</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1837528[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=324818">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=324818" target="_blank" href="/omim/608695">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/324818" ref="tree=GTR&ncbi_uid=324818&link_uid=324818" title="View MedGen record for 'Glaucoma 1, open angle, J'">Glaucoma 1, open angle, J</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1837527[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=324817">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=324817" target="_blank" href="/omim/608696">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/324817" ref="tree=GTR&ncbi_uid=324817&link_uid=324817" title="View MedGen record for 'Glaucoma 1, open angle, K'">Glaucoma 1, open angle, K</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1864653[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=400584">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=400584" target="_blank" href="/omim/610535">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/400584" ref="tree=GTR&ncbi_uid=400584&link_uid=400584" title="View MedGen record for 'Glaucoma 1, open angle, M'">Glaucoma 1, open angle, M</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1969812[DISCUI]&test_type=Research" ref="ncbi_uid=370756">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=370756" target="_blank" href="/omim/611274">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/370756" ref="tree=GTR&ncbi_uid=370756&link_uid=370756" title="View MedGen record for 'Glaucoma 1, open angle, N'">Glaucoma 1, open angle, N</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C2751294[DISCUI]&test_type=Clinical" ref="ncbi_uid=416515">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C2751294[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=416515">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=416515" target="_blank" href="/omim/162662">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=416515" ref="ncbi_uid=416515">V</a></span></span><span class="TLline"><a href="/medgen/416515" ref="tree=GTR&ncbi_uid=416515&link_uid=416515" title="View MedGen record for 'Glaucoma 1, open angle, O'">Glaucoma 1, open angle, O</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1866483[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=356544">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=356544" target="_blank" href="/omim/601682">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/356544" ref="tree=GTR&ncbi_uid=356544&link_uid=356544" title="View MedGen record for 'Glaucoma type 1C'">Glaucoma type 1C</a></span></li><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0339573[DISCUI]&test_type=Clinical" ref="ncbi_uid=87389">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C0339573[DISCUI]&test_type=Research" ref="ncbi_uid=87389">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=87389" target="_blank" href="/omim/137760">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=87389" ref="ncbi_uid=87389">V</a></span></span><span class="TLline">Primary open angle glaucoma</span></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/1370071" ref="tree=MeSH" title="MedGen record for Abnormality of the eye">Abnormality of the eye</a></span><ul><li><span class="TLline"><a href="/medgen/868525" ref="tree=MeSH" title="MedGen record for Abnormal eye physiology">Abnormal eye physiology</a></span><ul><li><span class="TLline"><a href="/medgen/42224" ref="tree=MeSH" title="MedGen record for Glaucoma">Glaucoma</a></span><ul><li><span class="matched_ds">Primary open angle glaucoma</span></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36920817">Glaucoma: Diagnosis and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Michels TC,
|
||
Ivan O</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2023 Mar;107(3):253-262.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36920817" target="_blank">36920817</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34933745">Primary Open-Angle Glaucoma Preferred Practice Pattern®.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gedde SJ,
|
||
Vinod K,
|
||
Wright MM,
|
||
Muir KW,
|
||
Lind JT,
|
||
Chen PP,
|
||
Li T,
|
||
Mansberger SL;
|
||
American Academy of Ophthalmology Preferred Practice Pattern Glaucoma Panel</span><br />
|
||
<span class="medgenPMjournal">Ophthalmology</span>
|
||
2021 Jan;128(1):P71-P150.
|
||
Epub 2020 Nov 12
|
||
doi: 10.1016/j.ophtha.2020.10.022.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34933745" target="_blank">34933745</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34933743">Primary Open-Angle Glaucoma Suspect Preferred Practice Pattern®.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gedde SJ,
|
||
Lind JT,
|
||
Wright MM,
|
||
Chen PP,
|
||
Muir KW,
|
||
Vinod K,
|
||
Li T,
|
||
Mansberger SL;
|
||
American Academy of Ophthalmology Preferred Practice Pattern Glaucoma Panel</span><br />
|
||
<span class="medgenPMjournal">Ophthalmology</span>
|
||
2021 Jan;128(1):P151-P192.
|
||
Epub 2020 Nov 12
|
||
doi: 10.1016/j.ophtha.2020.10.023.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34933743" target="_blank">34933743</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22primary%20open%20angle%20glaucoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (388)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng81" target="_blank">UK NICE Guideline NG81, Glaucoma: diagnosis and management</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38904834">Double implantation of Xen 45 gel stent in primary open-angle glaucoma: a pilot study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Grosso A,
|
||
Ceruti P,
|
||
Garlasco J,
|
||
Fröhlich J,
|
||
Orione M,
|
||
Gugleta K,
|
||
Fioretto M,
|
||
Calzetti G</span><br />
|
||
<span class="medgenPMjournal">Int Ophthalmol</span>
|
||
2024 Jun 21;44(1):243.
|
||
doi: 10.1007/s10792-024-03153-2.
|
||
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<div class="nl"><a target="_blank" href="/pubmed/32958214">Genetics of primary open-angle glaucoma and its endophenotypes.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Sakurada Y,
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Mabuchi F,
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<div class="nl"><a target="_blank" href="/pubmed/30430469">The determinants of therapeutic observance in open-angle glaucoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Amara F,
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Ben Amor H,
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Kaibi I,
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Taktak M,
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Taktak J</span><br />
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<div class="nl"><a target="_blank" href="/pubmed/23346803">Influence of rheological factors on the development of primary open angle glaucoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Michalska-Małecka K,
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<div class="nl"><a target="_blank" href="/pubmed/10149671">Diagnosis and follow-up of primary open-angle glaucoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Morrison JC</span><br />
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<div class="nl"><a target="_blank" href="/pubmed/36521470">Screening for Primary Open-Angle Glaucoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Jin J</span><br />
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<div class="nl"><a target="_blank" href="/pubmed/15158634">Primary open-angle glaucoma.</a></div>
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Rubin G,
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<span class="medgenPMjournal">Lancet</span>
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2019 Apr 13;393(10180):1505-1516.
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Epub 2019 Mar 9
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<div class="nl"><a target="_blank" href="/pubmed/29582808">Simplifying "target" intraocular pressure for different stages of primary open-angle glaucoma and primary angle-closure glaucoma.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/26526633">Comparative Effectiveness of First-Line Medications for Primary Open-Angle Glaucoma: A Systematic Review and Network Meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Li T,
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Lindsley K,
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Rouse B,
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<div class="nl"><a target="_blank" href="/pubmed/10577657">Glaucoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Coleman AL</span><br />
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Primary%20open%20angle%20glaucoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2198)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38904834">Double implantation of Xen 45 gel stent in primary open-angle glaucoma: a pilot study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Grosso A,
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<div class="nl"><a target="_blank" href="/pubmed/32071036">Optic disc haemorrhage and primary open-angle glaucoma: a clinical review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Jasty U,
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Harris A,
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Siesky B,
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Verticchio Vercellin AC,
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<div class="portlet_content ln"><span class="medgenPMauthor">Kondkar AA,
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Azad TA,
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Almobarak FA,
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Abu-Amero KK,
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<div class="nl"><a target="_blank" href="/pubmed/10149671">Diagnosis and follow-up of primary open-angle glaucoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Morrison JC</span><br />
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<span class="medgenPMjournal">Curr Opin Ophthalmol</span>
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<span class="bold">PMID: </span><a href="/pubmed/10149671" target="_blank">10149671</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/3189477">Intraocular pressure response to topical dexamethasone as a predictor for the development of primary open-angle glaucoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Lewis JM,
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Priddy T,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Primary%20open%20angle%20glaucoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1499)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37602651">Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/33075485">Inflammation in Glaucoma: From the back to the front of the eye, and beyond.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Baudouin C,
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<span class="bold">PMID: </span><a href="/pubmed/33075485" target="_blank">33075485</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/32958214">Genetics of primary open-angle glaucoma and its endophenotypes.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Sakurada Y,
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Mabuchi F,
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Kashiwagi K</span><br />
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<span class="medgenPMjournal">Prog Brain Res</span>
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2020;256(1):31-47.
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Epub 2020 Jul 1
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doi: 10.1016/bs.pbr.2020.06.001.
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<span class="bold">PMID: </span><a href="/pubmed/32958214" target="_blank">32958214</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/32414512">Aqueous humor interleukin-6 levels in primary open-angle glaucoma (POAG): A systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ulhaq ZS,
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Soraya GV</span><br />
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Epub 2020 May 12
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doi: 10.1016/j.oftal.2020.03.018.
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<span class="bold">PMID: </span><a href="/pubmed/32414512" target="_blank">32414512</a></div>
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||
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||
<div class="nl"><a target="_blank" href="/pubmed/30430469">The determinants of therapeutic observance in open-angle glaucoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Amara F,
|
||
Ben Amor H,
|
||
Kaibi I,
|
||
Taktak M,
|
||
Taktak J</span><br />
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<span class="medgenPMjournal">Tunis Med</span>
|
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2018 Jun;96(6):335-338.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30430469" target="_blank">30430469</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Primary%20open%20angle%20glaucoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2049)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/32414512">Aqueous humor interleukin-6 levels in primary open-angle glaucoma (POAG): A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ulhaq ZS,
|
||
Soraya GV</span><br />
|
||
<span class="medgenPMjournal">Arch Soc Esp Oftalmol (Engl Ed)</span>
|
||
2020 Jul;95(7):315-321.
|
||
Epub 2020 May 12
|
||
doi: 10.1016/j.oftal.2020.03.018.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32414512" target="_blank">32414512</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30430469">The determinants of therapeutic observance in open-angle glaucoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Amara F,
|
||
Ben Amor H,
|
||
Kaibi I,
|
||
Taktak M,
|
||
Taktak J</span><br />
|
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<span class="medgenPMjournal">Tunis Med</span>
|
||
2018 Jun;96(6):335-338.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30430469" target="_blank">30430469</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/28850575">Minimally-invasive glaucoma surgeries (MIGS) for open angle glaucoma: A systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Lavia C,
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Dallorto L,
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Maule M,
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Ceccarelli M,
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Fea AM</span><br />
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<span class="medgenPMjournal">PLoS One</span>
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Epub 2017 Aug 29
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<span class="bold">PMID: </span><a href="/pubmed/28850575" target="_blank">28850575</a><a href="/pmc/articles/PMC5574616" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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|
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<div class="nl"><a target="_blank" href="/pubmed/26526633">Comparative Effectiveness of First-Line Medications for Primary Open-Angle Glaucoma: A Systematic Review and Network Meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Li T,
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Lindsley K,
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Rouse B,
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Hong H,
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Shi Q,
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Friedman DS,
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Wormald R,
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Dickersin K</span><br />
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<span class="medgenPMjournal">Ophthalmology</span>
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2016 Jan;123(1):129-40.
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Epub 2015 Oct 31
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<span class="bold">PMID: </span><a href="/pubmed/26526633" target="_blank">26526633</a><a href="/pmc/articles/PMC4695285" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/24974815">Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Tham YC,
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Li X,
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Wong TY,
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Quigley HA,
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Aung T,
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Cheng CY</span><br />
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<span class="medgenPMjournal">Ophthalmology</span>
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2014 Nov;121(11):2081-90.
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Epub 2014 Jun 26
|
||
doi: 10.1016/j.ophtha.2014.05.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24974815" target="_blank">24974815</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Primary%20open%20angle%20glaucoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (86)</a></div></div>
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0339573%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (12)</a></li>
|
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<li><a href="/gtr/tests?term=C0339573%5bDISCUI%5d&test_type=Research" target="_blank">Research (2)</a></li>
|
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<li><a href="/gtr/tests?term=C0339573%5bDISCUI%5d&filter=method%3A2%5F9" target="_blank">Sequence analysis of select exons (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0339573%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (19)</a></li>
|
||
<li><a href="/gtr/tests?term=C0339573%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (2)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0339573%5bDISCUI%5d" target="_blank">See all (23)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=137760" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Primary%20open%20angle%20glaucoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22primary%20open%20angle%20glaucoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Primary%20open%20angle%20glaucoma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng81">NICE, 2022</a><div>UK NICE Guideline NG81, Glaucoma: diagnosis and management</div></li></ul></div>
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