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<meta name="keywords" content="C0152021, abnormalities, heart, abnormality, heart, chd, chd - congenital heart disease, congenital abnormality, congenital anomaly of heart, congenital heart defect, congenital heart defects, congenital heart disease, defect, congenital heart, defects, congenital heart, heart abnormalities, heart abnormality, heart defect, heart defect, congenital, heart, malformation of, heart-congenital defect, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="People with CCHD have one or more specific heart defects. The heart defects classified as CCHD include coarctation of the aorta, double-outlet right ventricle, D-transposition of the great arteries, Ebstein anomaly, hypoplastic left heart syndrome, interrupted aortic arch, pulmonary atresia with intact septum, single ventricle, total anomalous pulmonary venous connection, tetralogy of Fallot, tricuspid atresia, and truncus arteriosus.\n\nEach of the heart defects associated with CCHD affects the flow of blood into, out of, or through the heart. Some of the heart defects involve structures within the heart itself, such as the two lower chambers of the heart (the ventricles) or the valves that control blood flow through the heart. Others affect the structure of the large blood vessels leading into and out of the heart (including the aorta and pulmonary artery). Still others involve a combination of these structural abnormalities.\n\nSome people with treated CCHD have few related health problems later in life. However, long-term effects of CCHD can include delayed development and reduced stamina during exercise. Adults with these heart defects have an increased risk of abnormal heart rhythms, heart failure, sudden cardiac arrest, stroke, and premature death.\n\nAlthough babies with CCHD may appear healthy for the first few hours or days of life, signs and symptoms soon become apparent. These can include an abnormal heart sound during a heartbeat (heart murmur), rapid breathing (tachypnea), low blood pressure (hypotension), low levels of oxygen in the blood (hypoxemia), and a blue or purple tint to the skin caused by a shortage of oxygen (cyanosis). If untreated, CCHD can lead to shock, coma, and death. However, most people with CCHD now survive past infancy due to improvements in early detection, diagnosis, and treatment.\n\nCritical congenital heart disease (CCHD) is a term that refers to a group of serious heart defects that are present from birth. These abnormalities result from problems with the formation of one or more parts of the heart during the early stages of embryonic development. CCHD prevents the heart from pumping blood effectively or reduces the amount of oxygen in the blood. As a result, organs and tissues throughout the body do not receive enough oxygen, which can lead to organ damage and life-threatening complications. Individuals with CCHD usually require surgery soon after birth." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=57501
|
||
ConceptID=C0152021
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Congenital heart disease<span class="h1sub">(CHD)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>57501</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0152021</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>CHD</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Congenital heart disease (13213009); CHD - Congenital heart disease (13213009)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0005453" target="_blank">MONDO:0005453</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">People with CCHD have one or more specific heart defects. The heart defects classified as CCHD include coarctation of the aorta, double-outlet right ventricle, D-transposition of the great arteries, Ebstein anomaly, hypoplastic left heart syndrome, interrupted aortic arch, pulmonary atresia with intact septum, single ventricle, total anomalous pulmonary venous connection, tetralogy of Fallot, tricuspid atresia, and truncus arteriosus.<br /><br />Each of the heart defects associated with CCHD affects the flow of blood into, out of, or through the heart. Some of the heart defects involve structures within the heart itself, such as the two lower chambers of the heart (the ventricles) or the valves that control blood flow through the heart. Others affect the structure of the large blood vessels leading into and out of the heart (including the aorta and pulmonary artery). Still others involve a combination of these structural abnormalities.<br /><br />Some people with treated CCHD have few related health problems later in life. However, long-term effects of CCHD can include delayed development and reduced stamina during exercise. Adults with these heart defects have an increased risk of abnormal heart rhythms, heart failure, sudden cardiac arrest, stroke, and premature death.<br /><br />Although babies with CCHD may appear healthy for the first few hours or days of life, signs and symptoms soon become apparent. These can include an abnormal heart sound during a heartbeat (heart murmur), rapid breathing (tachypnea), low blood pressure (hypotension), low levels of oxygen in the blood (hypoxemia), and a blue or purple tint to the skin caused by a shortage of oxygen (cyanosis). If untreated, CCHD can lead to shock, coma, and death. However, most people with CCHD now survive past infancy due to improvements in early detection, diagnosis, and treatment.<br /><br />Critical congenital heart disease (CCHD) is a term that refers to a group of serious heart defects that are present from birth. These abnormalities result from problems with the formation of one or more parts of the heart during the early stages of embryonic development. CCHD prevents the heart from pumping blood effectively or reduces the amount of oxygen in the blood. As a result, organs and tissues throughout the body do not receive enough oxygen, which can lead to organ damage and life-threatening complications. Individuals with CCHD usually require surgery soon after birth. [from <a title="MedlinePlus Genetics" href="https://medlineplus.gov/genetics/" class="defSource" target="_blank">MedlinePlus Genetics</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0152021[DISCUI]&test_type=Clinical" ref="ncbi_uid=57501">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=57501" ref="ncbi_uid=57501">V</a></span></span><span class="TLline">Congenital heart disease</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/871309" ref="tree=MeSH" title="MedGen record for Abnormality of prenatal development or birth">Abnormality of prenatal development or birth</a></span><ul><li><span class="TLline"><a href="/medgen/1254" ref="tree=MeSH" title="MedGen record for Fetal anomaly">Fetal anomaly</a></span><ul><li><span class="TLline"><a href="/medgen/474891" ref="tree=MeSH" title="MedGen record for Congenital Systemic Disorder">Congenital Systemic Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/777113" ref="tree=MeSH" title="MedGen record for Congenital anomaly of cardiovascular system">Congenital anomaly of cardiovascular system</a></span><ul><li><span class="matched_ds">Congenital heart disease</span><ul><li><span class="TLline"><a href="/medgen/6748" ref="tree=MeSH" title="MedGen record for Abnormal heart morphology">Abnormal heart morphology</a></span><ul><li><span class="TLline"><a href="/medgen/422333" ref="tree=MeSH" title="MedGen record for 22q11 Deletion Syndrome">22q11 Deletion Syndrome</a></span><ul><li><span class="TLline"><a href="/medgen/4297" ref="tree=MeSH" title="MedGen record for DiGeorge syndrome">DiGeorge syndrome</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/107893" ref="tree=MeSH" title="MedGen record for 3-Methylglutaconic aciduria type 2">3-Methylglutaconic aciduria type 2</a></span></li><li><span class="TLline"><a href="/medgen/870897" ref="tree=MeSH" title="MedGen record for Abnormal anatomic location of the heart">Abnormal anatomic location of the heart</a></span><ul><li><span class="TLline"><a href="/medgen/868864" ref="tree=MeSH" title="MedGen record for Abnormal direction of ventricular apex">Abnormal direction of ventricular apex</a></span></li><li><span class="TLline"><a href="/medgen/4255" ref="tree=MeSH" title="MedGen record for Dextrocardia">Dextrocardia</a></span></li><li><span class="TLline"><a href="/medgen/41703" ref="tree=MeSH" title="MedGen record for Ectopia cordis">Ectopia cordis</a></span></li><li><span class="TLline"><a href="/medgen/488817" ref="tree=MeSH" title="MedGen record for Mesocardia">Mesocardia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1709890" ref="tree=MeSH" title="MedGen record for Abnormal bulbus cordis morphology">Abnormal bulbus cordis morphology</a></span></li><li><span class="TLline"><a href="/medgen/870789" ref="tree=MeSH" title="MedGen record for Abnormal cardiac atrium morphology">Abnormal cardiac atrium morphology</a></span><ul><li><span class="TLline"><a href="/medgen/488866" ref="tree=MeSH" title="MedGen record for Abnormal coronary sinus morphology">Abnormal coronary sinus morphology</a></span></li><li><span class="TLline"><a href="/medgen/1631247" ref="tree=MeSH" title="MedGen record for Abnormal left atrium morphology">Abnormal left atrium morphology</a></span></li><li><span class="TLline"><a href="/medgen/1646893" ref="tree=MeSH" title="MedGen record for Abnormal right atrium morphology">Abnormal right atrium morphology</a></span></li><li><span class="TLline"><a href="/medgen/1621471" ref="tree=MeSH" title="MedGen record for Atrial septal hypertrophy">Atrial septal hypertrophy</a></span></li><li><span class="TLline"><a href="/medgen/488886" ref="tree=MeSH" title="MedGen record for Common atrium">Common atrium</a></span></li><li><span class="TLline"><a href="/medgen/3238" ref="tree=MeSH" title="MedGen record for Triatrial heart">Triatrial heart</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1778223" ref="tree=MeSH" title="MedGen record for Abnormal cardiac magnetic resonance imaging finding">Abnormal cardiac magnetic resonance imaging finding</a></span><ul><li><span class="TLline"><a href="/medgen/1785178" ref="tree=MeSH" title="MedGen record for Elevated myocardial native T1">Elevated myocardial native T1</a></span></li><li><span class="TLline"><a href="/medgen/1788876" ref="tree=MeSH" title="MedGen record for Elevated myocardial native T2">Elevated myocardial native T2</a></span></li><li><span class="TLline"><a href="/medgen/1783233" ref="tree=MeSH" title="MedGen record for Myocardial late gadolinium enhancement">Myocardial late gadolinium enhancement</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1830392" ref="tree=MeSH" title="MedGen record for Abnormal cardiac septum morphology">Abnormal cardiac septum morphology</a></span><ul><li><span class="TLline"><a href="/medgen/488868" ref="tree=MeSH" title="MedGen record for Abnormal atrial septum morphology">Abnormal atrial septum morphology</a></span></li><li><span class="TLline"><a href="/medgen/235591" ref="tree=MeSH" title="MedGen record for Atrioventricular canal defect">Atrioventricular canal defect</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/871266" ref="tree=MeSH" title="MedGen record for Abnormal cardiac ventricle morphology">Abnormal cardiac ventricle morphology</a></span><ul><li><span class="TLline"><a href="/medgen/91037" ref="tree=MeSH" title="MedGen record for Abnormal left ventricle morphology">Abnormal left ventricle morphology</a></span></li><li><span class="TLline"><a href="/medgen/91036" ref="tree=MeSH" title="MedGen record for Abnormal right ventricle morphology">Abnormal right ventricle morphology</a></span></li><li><span class="TLline"><a href="/medgen/866908" ref="tree=MeSH" title="MedGen record for Abnormal ventricular septum morphology">Abnormal ventricular septum morphology</a></span></li><li><span class="TLline"><a href="/medgen/903640" ref="tree=MeSH" title="MedGen record for Cardiac diverticulum">Cardiac diverticulum</a></span></li><li><span class="TLline"><a href="/medgen/870552" ref="tree=MeSH" title="MedGen record for Myocardial steatosis">Myocardial steatosis</a></span></li><li><span class="TLline"><a href="/medgen/56289" ref="tree=MeSH" title="MedGen record for Single ventricle">Single ventricle</a></span></li><li><span class="TLline"><a href="/medgen/87400" ref="tree=MeSH" title="MedGen record for Ventricular hypertrophy">Ventricular hypertrophy</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/868895" ref="tree=MeSH" title="MedGen record for Abnormal connection of the cardiac segments">Abnormal connection of the cardiac segments</a></span><ul><li><span class="TLline"><a href="/medgen/488858" ref="tree=MeSH" title="MedGen record for Abnormal atrioventricular connection">Abnormal atrioventricular connection</a></span></li><li><span class="TLline"><a href="/medgen/754542" ref="tree=MeSH" title="MedGen record for Abnormal ventriculoarterial connection">Abnormal ventriculoarterial connection</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/867299" ref="tree=MeSH" title="MedGen record for Abnormal endocardium morphology">Abnormal endocardium morphology</a></span><ul><li><span class="TLline"><a href="/medgen/4041" ref="tree=MeSH" title="MedGen record for Endocardial fibroelastosis">Endocardial fibroelastosis</a></span></li><li><span class="TLline"><a href="/medgen/107513" ref="tree=MeSH" title="MedGen record for Endomyocardial fibrosis">Endomyocardial fibrosis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/892837" ref="tree=MeSH" title="MedGen record for Abnormal heart valve morphology">Abnormal heart valve morphology</a></span><ul><li><span class="TLline"><a href="/medgen/488999" ref="tree=MeSH" title="MedGen record for Abnormal aortic valve morphology">Abnormal aortic valve morphology</a></span></li><li><span class="TLline"><a href="/medgen/870547" ref="tree=MeSH" title="MedGen record for Abnormal atrioventricular valve morphology">Abnormal atrioventricular valve morphology</a></span></li><li><span class="TLline"><a href="/medgen/488998" ref="tree=MeSH" title="MedGen record for Abnormal pulmonary valve morphology">Abnormal pulmonary valve morphology</a></span></li><li><span class="TLline"><a href="/medgen/1864342" ref="tree=MeSH" title="MedGen record for Cardiac valve vegetations">Cardiac valve vegetations</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/871271" ref="tree=MeSH" title="MedGen record for Abnormal myocardium morphology">Abnormal myocardium morphology</a></span><ul><li><span class="TLline"><a href="/medgen/892696" ref="tree=MeSH" title="MedGen record for Abnormal morphology of myocardial trabeculae">Abnormal morphology of myocardial trabeculae</a></span></li><li><span class="TLline"><a href="/medgen/1617610" ref="tree=MeSH" title="MedGen record for Abnormal ventricular myocardium morphology">Abnormal ventricular myocardium morphology</a></span></li><li><span class="TLline"><a href="/medgen/1841855" ref="tree=MeSH" title="MedGen record for Cardiac polyglucosan accumulation">Cardiac polyglucosan accumulation</a></span></li><li><span class="TLline"><a href="/medgen/209232" ref="tree=MeSH" title="MedGen record for Cardiomyopathy">Cardiomyopathy</a></span></li><li><span class="TLline"><a href="/medgen/1863473" ref="tree=MeSH" title="MedGen record for Elevated myocardial iron load">Elevated myocardial iron load</a></span></li><li><span class="TLline"><a href="/medgen/1614677" ref="tree=MeSH" title="MedGen record for Fatty replacement of ventricular myocardial tissue">Fatty replacement of ventricular myocardial tissue</a></span></li><li><span class="TLline"><a href="/medgen/871154" ref="tree=MeSH" title="MedGen record for Focal necrosis of right ventricular muscle cells">Focal necrosis of right ventricular muscle cells</a></span></li><li><span class="TLline"><a href="/medgen/1841883" ref="tree=MeSH" title="MedGen record for Increased myocardial glycogen content">Increased myocardial glycogen content</a></span></li><li><span class="TLline"><a href="/medgen/1863997" ref="tree=MeSH" title="MedGen record for Increased myocardial pyrophosphate uptake">Increased myocardial pyrophosphate uptake</a></span></li><li><span class="TLline"><a href="/medgen/56239" ref="tree=MeSH" title="MedGen record for Myocardial fibrosis">Myocardial fibrosis</a></span></li><li><span class="TLline"><a href="/medgen/1627222" ref="tree=MeSH" title="MedGen record for Myocardial immune cell infiltration">Myocardial immune cell infiltration</a></span></li><li><span class="TLline"><a href="/medgen/254841" ref="tree=MeSH" title="MedGen record for Myocardial necrosis">Myocardial necrosis</a></span></li><li><span class="TLline"><a href="/medgen/44553" ref="tree=MeSH" title="MedGen record for Myocarditis">Myocarditis</a></span></li><li><span class="TLline"><a href="/medgen/1615672" ref="tree=MeSH" title="MedGen record for Myofiber disarray">Myofiber disarray</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/871268" ref="tree=MeSH" title="MedGen record for Abnormal pericardium morphology">Abnormal pericardium morphology</a></span><ul><li><span class="TLline"><a href="/medgen/868851" ref="tree=MeSH" title="MedGen record for Congenital defect of the pericardium">Congenital defect of the pericardium</a></span></li><li><span class="TLline"><a href="/medgen/116108" ref="tree=MeSH" title="MedGen record for Pericardial constriction">Pericardial constriction</a></span></li><li><span class="TLline"><a href="/medgen/10653" ref="tree=MeSH" title="MedGen record for Pericardial effusion">Pericardial effusion</a></span></li><li><span class="TLline"><a href="/medgen/1778734" ref="tree=MeSH" title="MedGen record for Pericardial late gadolinium enhancement">Pericardial late gadolinium enhancement</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/868902" ref="tree=MeSH" title="MedGen record for Abnormal spatial orientation of the cardiac segments">Abnormal spatial orientation of the cardiac segments</a></span><ul><li><span class="TLline"><a href="/medgen/488996" ref="tree=MeSH" title="MedGen record for Abnormal atrial arrangement">Abnormal atrial arrangement</a></span></li><li><span class="TLline"><a href="/medgen/868899" ref="tree=MeSH" title="MedGen record for Criss-cross atrioventricular valves">Criss-cross atrioventricular valves</a></span></li><li><span class="TLline"><a href="/medgen/868896" ref="tree=MeSH" title="MedGen record for L-looping of the right ventricle">L-looping of the right ventricle</a></span></li><li><span class="TLline"><a href="/medgen/1642262" ref="tree=MeSH" title="MedGen record for Situs inversus">Situs inversus</a></span></li><li><span class="TLline"><a href="/medgen/7331" ref="tree=MeSH" title="MedGen record for Situs inversus with levocardia">Situs inversus with levocardia</a></span></li><li><span class="TLline"><a href="/medgen/868897" ref="tree=MeSH" title="MedGen record for Superior-inferior ventricles without criss-cross atrioventricular valves">Superior-inferior ventricles without criss-cross atrioventricular valves</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/868852" ref="tree=MeSH" title="MedGen record for Aorto-ventricular tunnel">Aorto-ventricular tunnel</a></span><ul><li><span class="TLline"><a href="/medgen/576719" ref="tree=MeSH" title="MedGen record for Aorto-left ventricular tunnel">Aorto-left ventricular tunnel</a></span></li><li><span class="TLline"><a href="/medgen/576720" ref="tree=MeSH" title="MedGen record for Aorto-right ventricular tunnel">Aorto-right ventricular tunnel</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87618" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular cardiomyopathy">Arrhythmogenic right ventricular cardiomyopathy</a></span><ul><li><span class="TLline"><a href="/medgen/349530" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 1">Arrhythmogenic right ventricular dysplasia 1</a></span></li><li><span class="TLline"><a href="/medgen/318748" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 2">Arrhythmogenic right ventricular dysplasia 2</a></span></li><li><span class="TLline"><a href="/medgen/356108" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 3">Arrhythmogenic right ventricular dysplasia 3</a></span></li><li><span class="TLline"><a href="/medgen/356107" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 4">Arrhythmogenic right ventricular dysplasia 4</a></span></li><li><span class="TLline"><a href="/medgen/346805" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 5">Arrhythmogenic right ventricular dysplasia 5</a></span></li><li><span class="TLline"><a href="/medgen/346892" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 6">Arrhythmogenic right ventricular dysplasia 6</a></span></li><li><span class="TLline"><a href="/medgen/336069" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 8">Arrhythmogenic right ventricular dysplasia 8</a></span></li><li><span class="TLline"><a href="/medgen/373205" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 9">Arrhythmogenic right ventricular dysplasia 9</a></span></li><li><span class="TLline"><a href="/medgen/347543" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 10">Arrhythmogenic right ventricular dysplasia 10</a></span></li><li><span class="TLline"><a href="/medgen/351237" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 11">Arrhythmogenic right ventricular dysplasia 11</a></span></li><li><span class="TLline"><a href="/medgen/409749" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 12">Arrhythmogenic right ventricular dysplasia 12</a></span></li><li><span class="TLline"><a href="/medgen/816468" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia 13">Arrhythmogenic right ventricular dysplasia 13</a></span></li><li><span class="TLline"><a href="/medgen/373153" ref="tree=MeSH" title="MedGen record for Arrhythmogenic right ventricular dysplasia, familial, 7">Arrhythmogenic right ventricular dysplasia, familial, 7</a></span></li><li><span class="TLline"><a href="/medgen/901869" ref="tree=MeSH" title="MedGen record for Familial isolated arrhythmogenic right ventricular dysplasia">Familial isolated arrhythmogenic right ventricular dysplasia</a></span></li><li><span class="TLline"><a href="/medgen/321991" ref="tree=MeSH" title="MedGen record for Naxos disease">Naxos disease</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/39014" ref="tree=MeSH" title="MedGen record for Arteriohepatic dysplasia">Arteriohepatic dysplasia</a></span><ul><li><span class="TLline"><a href="/medgen/1826025" ref="tree=MeSH" title="MedGen record for Alagille syndrome due to 20p12 microdeletion">Alagille syndrome due to 20p12 microdeletion</a></span></li><li><span class="TLline"><a href="/medgen/365434" ref="tree=MeSH" title="MedGen record for Alagille syndrome due to a JAG1 point mutation">Alagille syndrome due to a JAG1 point mutation</a></span></li><li><span class="TLline"><a href="/medgen/341844" ref="tree=MeSH" title="MedGen record for Alagille syndrome due to a NOTCH2 point mutation">Alagille syndrome due to a NOTCH2 point mutation</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/57436" ref="tree=MeSH" title="MedGen record for Bicuspid aortic valve">Bicuspid aortic valve</a></span><ul><li><span class="TLline"><a href="/medgen/1373386" ref="tree=MeSH" title="MedGen record for Purely bicuspid aortic valve">Purely bicuspid aortic valve</a></span></li><li><span class="TLline"><a href="/medgen/1385423" ref="tree=MeSH" title="MedGen record for Single raphe bicuspid aortic valve">Single raphe bicuspid aortic valve</a></span></li><li><span class="TLline"><a href="/medgen/1376892" ref="tree=MeSH" title="MedGen record for Two-raphe bicuspid aortic valve">Two-raphe bicuspid aortic valve</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1863420" ref="tree=MeSH" title="MedGen record for Boot-shaped cardiac silhouette">Boot-shaped cardiac silhouette</a></span></li><li><span class="TLline"><a href="/medgen/1864377" ref="tree=MeSH" title="MedGen record for Cardiac mass">Cardiac mass</a></span></li><li><span class="TLline"><a href="/medgen/5459" ref="tree=MeSH" title="MedGen record for Cardiomegaly">Cardiomegaly</a></span><ul><li><span class="TLline"><a href="/medgen/151958" ref="tree=MeSH" title="MedGen record for Cardiomegaly due to hypertension">Cardiomegaly due to hypertension</a></span></li><li><span class="TLline"><a href="/medgen/57442" ref="tree=MeSH" title="MedGen record for Left ventricular hypertrophy">Left ventricular hypertrophy</a></span></li><li><span class="TLline"><a href="/medgen/2880" ref="tree=MeSH" title="MedGen record for Primary dilated cardiomyopathy">Primary dilated cardiomyopathy</a></span></li><li><span class="TLline"><a href="/medgen/57981" ref="tree=MeSH" title="MedGen record for Right ventricular hypertrophy">Right ventricular hypertrophy</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1617" ref="tree=MeSH" title="MedGen record for Coarctation of aorta">Coarctation of aorta</a></span><ul><li><span class="TLline"><a href="/medgen/758831" ref="tree=MeSH" title="MedGen record for Atypical coarctation of aorta">Atypical coarctation of aorta</a></span></li><li><span class="TLline"><a href="/medgen/443900" ref="tree=MeSH" title="MedGen record for Autosomal dominant coarctation of aorta">Autosomal dominant coarctation of aorta</a></span></li><li><span class="TLline"><a href="/medgen/1385566" ref="tree=MeSH" title="MedGen record for Coarctation in the transverse aortic arch">Coarctation in the transverse aortic arch</a></span></li><li><span class="TLline"><a href="/medgen/870806" ref="tree=MeSH" title="MedGen record for Coarctation of abdominal aorta">Coarctation of abdominal aorta</a></span></li><li><span class="TLline"><a href="/medgen/1378073" ref="tree=MeSH" title="MedGen record for Long segment coarctation of the aorta">Long segment coarctation of the aorta</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/868006" ref="tree=MeSH" title="MedGen record for Congenital malformation of the left heart">Congenital malformation of the left heart</a></span><ul><li><span class="TLline"><a href="/medgen/57746" ref="tree=MeSH" title="MedGen record for Hypoplastic left heart syndrome">Hypoplastic left heart syndrome</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/868809" ref="tree=MeSH" title="MedGen record for Congenital malformation of the right heart">Congenital malformation of the right heart</a></span><ul><li><span class="TLline"><a href="/medgen/41649" ref="tree=MeSH" title="MedGen record for Double outlet right ventricle">Double outlet right ventricle</a></span></li><li><span class="TLline"><a href="/medgen/451017" ref="tree=MeSH" title="MedGen record for Hypoplastic right heart">Hypoplastic right heart</a></span></li><li><span class="TLline"><a href="/medgen/78576" ref="tree=MeSH" title="MedGen record for Uhl anomaly">Uhl anomaly</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/3627" ref="tree=MeSH" title="MedGen record for Coronary Vessel Anomalies">Coronary Vessel Anomalies</a></span><ul><li><span class="TLline"><a href="/medgen/1676988" ref="tree=MeSH" title="MedGen record for Anomalous Left Coronary Artery">Anomalous Left Coronary Artery</a></span></li><li><span class="TLline"><a href="/medgen/760471" ref="tree=MeSH" title="MedGen record for Anomalous origin of left coronary artery from the pulmonary artery">Anomalous origin of left coronary artery from the pulmonary artery</a></span></li><li><span class="TLline"><a href="/medgen/182684" ref="tree=MeSH" title="MedGen record for Myocardial bridging">Myocardial bridging</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/8181" ref="tree=MeSH" title="MedGen record for Criss-cross heart">Criss-cross heart</a></span></li><li><span class="TLline"><a href="/medgen/4435" ref="tree=MeSH" title="MedGen record for Ebstein anomaly">Ebstein anomaly</a></span></li><li><span class="TLline"><a href="/medgen/4479" ref="tree=MeSH" title="MedGen record for Eisenmenger syndrome">Eisenmenger syndrome</a></span></li><li><span class="TLline"><a href="/medgen/52848" ref="tree=MeSH" title="MedGen record for Fallot trilogy">Fallot trilogy</a></span></li><li><span class="TLline"><a href="/medgen/6752" ref="tree=MeSH" title="MedGen record for Heart septal defect">Heart septal defect</a></span><ul><li><span class="TLline"><a href="/medgen/895830" ref="tree=MeSH" title="MedGen record for Aorticopulmonary Septal Defect">Aorticopulmonary Septal Defect</a></span></li><li><span class="TLline"><a href="/medgen/365" ref="tree=MeSH" title="MedGen record for Aortopulmonary window">Aortopulmonary window</a></span></li><li><span class="TLline"><a href="/medgen/6753" ref="tree=MeSH" title="MedGen record for Atrial septal defect">Atrial septal defect</a></span></li><li><span class="TLline"><a href="/medgen/501123" ref="tree=MeSH" title="MedGen record for Atrioventricular septal defect">Atrioventricular septal defect</a></span></li><li><span class="TLline"><a href="/medgen/41778" ref="tree=MeSH" title="MedGen record for Endocardial cushion defect">Endocardial cushion defect</a></span></li><li><span class="TLline"><a href="/medgen/42366" ref="tree=MeSH" title="MedGen record for Ventricular septal defect">Ventricular septal defect</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/462875" ref="tree=MeSH" title="MedGen record for Hypoplastic heart">Hypoplastic heart</a></span></li><li><span class="TLline"><a href="/medgen/403467" ref="tree=MeSH" title="MedGen record for Isolated Noncompaction of the Ventricular Myocardium">Isolated Noncompaction of the Ventricular Myocardium</a></span></li><li><span class="TLline"><a href="/medgen/44193" ref="tree=MeSH" title="MedGen record for Long QT syndrome">Long QT syndrome</a></span><ul><li><span class="TLline"><a href="/medgen/327586" ref="tree=MeSH" title="MedGen record for Andersen Tawil syndrome">Andersen Tawil syndrome</a></span></li><li><span class="TLline"><a href="/medgen/685787" ref="tree=MeSH" title="MedGen record for Congenital long QT syndrome">Congenital long QT syndrome</a></span></li><li><span class="TLline"><a href="/medgen/5929" ref="tree=MeSH" title="MedGen record for Jervell and Lange-Nielsen syndrome">Jervell and Lange-Nielsen syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1641146" ref="tree=MeSH" title="MedGen record for Long QT syndrome 1">Long QT syndrome 1</a></span></li><li><span class="TLline"><a href="/medgen/462293" ref="tree=MeSH" title="MedGen record for Long QT syndrome 2">Long QT syndrome 2</a></span></li><li><span class="TLline"><a href="/medgen/349087" ref="tree=MeSH" title="MedGen record for Long QT syndrome 3">Long QT syndrome 3</a></span></li><li><span class="TLline"><a href="/medgen/358092" ref="tree=MeSH" title="MedGen record for Long QT syndrome 5">Long QT syndrome 5</a></span></li><li><span class="TLline"><a href="/medgen/864108" ref="tree=MeSH" title="MedGen record for Long QT syndrome 14">Long QT syndrome 14</a></span></li><li><span class="TLline"><a href="/medgen/331395" ref="tree=MeSH" title="MedGen record for Timothy syndrome">Timothy syndrome</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/44287" ref="tree=MeSH" title="MedGen record for Marfan syndrome">Marfan syndrome</a></span><ul><li><span class="TLline"><a href="/medgen/443966" ref="tree=MeSH" title="MedGen record for Loeys-Dietz Syndrome Type 2">Loeys-Dietz Syndrome Type 2</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/18073" ref="tree=MeSH" title="MedGen record for Noonan syndrome">Noonan syndrome</a></span><ul><li><span class="TLline"><a href="/medgen/1638960" ref="tree=MeSH" title="MedGen record for Noonan syndrome 1">Noonan syndrome 1</a></span></li><li><span class="TLline"><a href="/medgen/344290" ref="tree=MeSH" title="MedGen record for Noonan syndrome 2">Noonan syndrome 2</a></span></li><li><span class="TLline"><a href="/medgen/349931" ref="tree=MeSH" title="MedGen record for Noonan syndrome 3">Noonan syndrome 3</a></span></li><li><span class="TLline"><a href="/medgen/339908" ref="tree=MeSH" title="MedGen record for Noonan syndrome 4">Noonan syndrome 4</a></span></li><li><span class="TLline"><a href="/medgen/370589" ref="tree=MeSH" title="MedGen record for Noonan syndrome 5">Noonan syndrome 5</a></span></li><li><span class="TLline"><a href="/medgen/413028" ref="tree=MeSH" title="MedGen record for Noonan syndrome 6">Noonan syndrome 6</a></span></li><li><span class="TLline"><a href="/medgen/462320" ref="tree=MeSH" title="MedGen record for Noonan syndrome 7">Noonan syndrome 7</a></span></li><li><span class="TLline"><a href="/medgen/815563" ref="tree=MeSH" title="MedGen record for Noonan syndrome 8">Noonan syndrome 8</a></span></li><li><span class="TLline"><a href="/medgen/896352" ref="tree=MeSH" title="MedGen record for Noonan syndrome 9">Noonan syndrome 9</a></span></li><li><span class="TLline"><a href="/medgen/902892" ref="tree=MeSH" title="MedGen record for Noonan syndrome 10">Noonan syndrome 10</a></span></li><li><span class="TLline"><a href="/medgen/1681177" ref="tree=MeSH" title="MedGen record for Noonan syndrome 11">Noonan syndrome 11</a></span></li><li><span class="TLline"><a href="/medgen/1684730" ref="tree=MeSH" title="MedGen record for Noonan syndrome 12">Noonan syndrome 12</a></span></li><li><span class="TLline"><a href="/medgen/1761918" ref="tree=MeSH" title="MedGen record for Noonan syndrome 13">Noonan syndrome 13</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/104494" ref="tree=MeSH" title="MedGen record for Noonan syndrome with multiple lentigines">Noonan syndrome with multiple lentigines</a></span><ul><li><span class="TLline"><a href="/medgen/1631694" ref="tree=MeSH" title="MedGen record for LEOPARD syndrome 1">LEOPARD syndrome 1</a></span></li><li><span class="TLline"><a href="/medgen/370588" ref="tree=MeSH" title="MedGen record for LEOPARD syndrome 2">LEOPARD syndrome 2</a></span></li><li><span class="TLline"><a href="/medgen/462321" ref="tree=MeSH" title="MedGen record for LEOPARD syndrome 3">LEOPARD syndrome 3</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/4415" ref="tree=MeSH" title="MedGen record for Patent ductus arteriosus">Patent ductus arteriosus</a></span><ul><li><span class="TLline"><a href="/medgen/488905" ref="tree=MeSH" title="MedGen record for Bilateral ductus arteriosus">Bilateral ductus arteriosus</a></span></li><li><span class="TLline"><a href="/medgen/868839" ref="tree=MeSH" title="MedGen record for Patent ductus arteriosus after birth at term">Patent ductus arteriosus after birth at term</a></span></li><li><span class="TLline"><a href="/medgen/868838" ref="tree=MeSH" title="MedGen record for Patent ductus arteriosus after premature birth">Patent ductus arteriosus after premature birth</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/576685" ref="tree=MeSH" title="MedGen record for Quadricuspid aortic valve">Quadricuspid aortic valve</a></span></li><li><span class="TLline"><a href="/medgen/21498" ref="tree=MeSH" title="MedGen record for Tetralogy of Fallot">Tetralogy of Fallot</a></span><ul><li><span class="TLline"><a href="/medgen/768726" ref="tree=MeSH" title="MedGen record for Complete atrioventricular canal-tetralogy of fallot syndrome">Complete atrioventricular canal-tetralogy of fallot syndrome</a></span></li><li><span class="TLline"><a href="/medgen/868826" ref="tree=MeSH" title="MedGen record for Tetralogy of Fallot with absent subarterial conus">Tetralogy of Fallot with absent subarterial conus</a></span></li><li><span class="TLline"><a href="/medgen/868825" ref="tree=MeSH" title="MedGen record for Tetralogy of Fallot with atrioventricular canal defect">Tetralogy of Fallot with atrioventricular canal defect</a></span></li><li><span class="TLline"><a href="/medgen/576595" ref="tree=MeSH" title="MedGen record for Tetralogy of Fallot with pulmonary atresia">Tetralogy of Fallot with pulmonary atresia</a></span></li><li><span class="TLline"><a href="/medgen/488870" ref="tree=MeSH" title="MedGen record for Tetralogy of Fallot with pulmonary stenosis">Tetralogy of Fallot with pulmonary stenosis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/21245" ref="tree=MeSH" title="MedGen record for Transposition of the great arteries">Transposition of the great arteries</a></span><ul><li><span class="TLline"><a href="/medgen/462571" ref="tree=MeSH" title="MedGen record for Congenital heart defects, multiple types, 6">Congenital heart defects, multiple types, 6</a></span></li><li><span class="TLline"><a href="/medgen/87489" ref="tree=MeSH" title="MedGen record for Congenitally corrected transposition of the great arteries">Congenitally corrected transposition of the great arteries</a></span></li><li><span class="TLline"><a href="/medgen/699062" ref="tree=MeSH" title="MedGen record for D - transposition of the great vessels">D - transposition of the great vessels</a></span></li><li><span class="TLline"><a href="/medgen/1812310" ref="tree=MeSH" title="MedGen record for Dextro-looped transposition of the great arteries">Dextro-looped transposition of the great arteries</a></span></li><li><span class="TLline"><a href="/medgen/768659" ref="tree=MeSH" title="MedGen record for Dextro-Transposition of the Great Vessels with Intact Ventricular Septum">Dextro-Transposition of the Great Vessels with Intact Ventricular Septum</a></span></li><li><span class="TLline"><a href="/medgen/768660" ref="tree=MeSH" title="MedGen record for Dextro-Transposition of the Great Vessels with Ventricular Septal Defect">Dextro-Transposition of the Great Vessels with Ventricular Septal Defect</a></span></li><li><span class="TLline"><a href="/medgen/758887" ref="tree=MeSH" title="MedGen record for Dextrotransposition of the great arteries">Dextrotransposition of the great arteries</a></span></li><li><span class="TLline"><a href="/medgen/237904" ref="tree=MeSH" title="MedGen record for Heterotaxy, visceral, 2, autosomal">Heterotaxy, visceral, 2, autosomal</a></span></li><li><span class="TLline"><a href="/medgen/476121" ref="tree=MeSH" title="MedGen record for Levo-Transposition of the Great Arteries">Levo-Transposition of the Great Arteries</a></span></li><li><span class="TLline"><a href="/medgen/699035" ref="tree=MeSH" title="MedGen record for Levotransposition of the great arteries">Levotransposition of the great arteries</a></span></li><li><span class="TLline"><a href="/medgen/332422" ref="tree=MeSH" title="MedGen record for Transposition of the great arteries, dextro-looped">Transposition of the great arteries, dextro-looped</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/67034" ref="tree=MeSH" title="MedGen record for Tricuspid atresia">Tricuspid atresia</a></span><ul><li><span class="TLline"><a href="/medgen/576468" ref="tree=MeSH" title="MedGen record for Unguarded tricuspid valve">Unguarded tricuspid valve</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1379406" ref="tree=MeSH" title="MedGen record for Trisomy 13 Syndromes">Trisomy 13 Syndromes</a></span></li><li><span class="TLline"><a href="/medgen/1384417" ref="tree=MeSH" title="MedGen record for Trisomy 18">Trisomy 18</a></span></li><li><span class="TLline"><a href="/medgen/21734" ref="tree=MeSH" title="MedGen record for Turner syndrome">Turner syndrome</a></span><ul><li><span class="TLline"><a href="/medgen/116607" ref="tree=MeSH" title="MedGen record for Monosomy X">Monosomy X</a></span></li><li><span class="TLline"><a href="/medgen/873772" ref="tree=MeSH" title="MedGen record for Mosaic Turner syndrome">Mosaic Turner syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1842425" ref="tree=MeSH" title="MedGen record for Turner syndrome due to structural X chromosome anomalies">Turner syndrome due to structural X chromosome anomalies</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/465273" ref="tree=MeSH" title="MedGen record for Visceral heterotaxy">Visceral heterotaxy</a></span><ul><li><span class="TLline"><a href="/medgen/75620" ref="tree=MeSH" title="MedGen record for Heterotaxy">Heterotaxy</a></span></li><li><span class="TLline"><a href="/medgen/465274" ref="tree=MeSH" title="MedGen record for Right atrial isomerism">Right atrial isomerism</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/12162" ref="tree=MeSH" title="MedGen record for Wolff-Parkinson-White pattern">Wolff-Parkinson-White pattern</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/539575" ref="tree=MeSH" title="MedGen record for Abnormality of the pulmonary veins">Abnormality of the pulmonary veins</a></span><ul><li><span class="TLline"><a href="/medgen/1382214" ref="tree=MeSH" title="MedGen record for Abnormal pulmonary vein physiology">Abnormal pulmonary vein physiology</a></span></li><li><span class="TLline"><a href="/medgen/1648157" ref="tree=MeSH" title="MedGen record for Congenital total pulmonary venous return anomaly">Congenital total pulmonary venous return anomaly</a></span><ul><li><span class="TLline"><a href="/medgen/866779" ref="tree=MeSH" title="MedGen record for Cardiac total anomalous pulmonary venous connection">Cardiac total anomalous pulmonary venous connection</a></span></li><li><span class="TLline"><a href="/medgen/866778" ref="tree=MeSH" title="MedGen record for Infracardiac total anomalous pulmonary venous connection">Infracardiac total anomalous pulmonary venous connection</a></span></li><li><span class="TLline"><a href="/medgen/866777" ref="tree=MeSH" title="MedGen record for Mixed total anomalous pulmonary venous connection">Mixed total anomalous pulmonary venous connection</a></span></li><li><span class="TLline"><a href="/medgen/866780" ref="tree=MeSH" title="MedGen record for Supracardiac total anomalous pulmonary venous connection">Supracardiac total anomalous pulmonary venous connection</a></span></li><li><span class="TLline"><a href="/medgen/475906" ref="tree=MeSH" title="MedGen record for Type I Total Anomalous Pulmonary Venous Return">Type I Total Anomalous Pulmonary Venous Return</a></span></li><li><span class="TLline"><a href="/medgen/475908" ref="tree=MeSH" title="MedGen record for Type II Total Anomalous Pulmonary Venous Return">Type II Total Anomalous Pulmonary Venous Return</a></span></li><li><span class="TLline"><a href="/medgen/475913" ref="tree=MeSH" title="MedGen record for Type III Total Anomalous Pulmonary Venous Return">Type III Total Anomalous Pulmonary Venous Return</a></span></li><li><span class="TLline"><a href="/medgen/475914" ref="tree=MeSH" title="MedGen record for Type IV Total Anomalous Pulmonary Venous Return">Type IV Total Anomalous Pulmonary Venous Return</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/451016" ref="tree=MeSH" title="MedGen record for Aortic valve atresia">Aortic valve atresia</a></span></li><li><span class="TLline"><a href="/medgen/473062" ref="tree=MeSH" title="MedGen record for Congenital complete atrioventricular heart block">Congenital complete atrioventricular heart block</a></span></li><li><span class="TLline"><a href="/medgen/866782" ref="tree=MeSH" title="MedGen record for Left ventricular noncompaction cardiomyopathy">Left ventricular noncompaction cardiomyopathy</a></span><ul><li><span class="TLline"><a href="/medgen/767410" ref="tree=MeSH" title="MedGen record for Left ventricular noncompaction 7">Left ventricular noncompaction 7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/9872" ref="tree=MeSH" title="MedGen record for Malposition of Heart and Cardiac Apex">Malposition of Heart and Cardiac Apex</a></span></li><li><span class="TLline"><a href="/medgen/91035" ref="tree=MeSH" title="MedGen record for Mitral atresia disorder">Mitral atresia disorder</a></span></li><li><span class="TLline"><a href="/medgen/45825" ref="tree=MeSH" title="MedGen record for Ostium primum defect">Ostium primum defect</a></span></li><li><span class="TLline"><a href="/medgen/120559" ref="tree=MeSH" title="MedGen record for Overriding aorta">Overriding aorta</a></span></li><li><span class="TLline"><a href="/medgen/450995" ref="tree=MeSH" title="MedGen record for Partial anomalous pulmonary venous return">Partial anomalous pulmonary venous return</a></span><ul><li><span class="TLline"><a href="/medgen/20675" ref="tree=MeSH" title="MedGen record for Scimitar syndrome">Scimitar syndrome</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/8891" ref="tree=MeSH" title="MedGen record for Patent foramen ovale">Patent foramen ovale</a></span></li><li><span class="TLline"><a href="/medgen/52867" ref="tree=MeSH" title="MedGen record for Persistent truncus arteriosus">Persistent truncus arteriosus</a></span><ul><li><span class="TLline"><a href="/medgen/322536" ref="tree=MeSH" title="MedGen record for Type I truncus arteriosus">Type I truncus arteriosus</a></span></li><li><span class="TLline"><a href="/medgen/866786" ref="tree=MeSH" title="MedGen record for Type II truncus arteriosus">Type II truncus arteriosus</a></span></li><li><span class="TLline"><a href="/medgen/866785" ref="tree=MeSH" title="MedGen record for Type III truncus arteriosus">Type III truncus arteriosus</a></span></li><li><span class="TLline"><a href="/medgen/866784" ref="tree=MeSH" title="MedGen record for Type IV truncus arteriosus">Type IV truncus arteriosus</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/116684" ref="tree=MeSH" title="MedGen record for Pulmonary valve atresia">Pulmonary valve atresia</a></span><ul><li><span class="TLline"><a href="/medgen/87491" ref="tree=MeSH" title="MedGen record for Pulmonary atresia with intact ventricular septum">Pulmonary atresia with intact ventricular septum</a></span></li><li><span class="TLline"><a href="/medgen/87492" ref="tree=MeSH" title="MedGen record for Pulmonary atresia with ventricular septal defect">Pulmonary atresia with ventricular septal defect</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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||
</div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/36017548">2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Humbert M,
|
||
Kovacs G,
|
||
Hoeper MM,
|
||
Badagliacca R,
|
||
Berger RMF,
|
||
Brida M,
|
||
Carlsen J,
|
||
Coats AJS,
|
||
Escribano-Subias P,
|
||
Ferrari P,
|
||
Ferreira DS,
|
||
Ghofrani HA,
|
||
Giannakoulas G,
|
||
Kiely DG,
|
||
Mayer E,
|
||
Meszaros G,
|
||
Nagavci B,
|
||
Olsson KM,
|
||
Pepke-Zaba J,
|
||
Quint JK,
|
||
Rådegran G,
|
||
Simonneau G,
|
||
Sitbon O,
|
||
Tonia T,
|
||
Toshner M,
|
||
Vachiery JL,
|
||
Vonk Noordegraaf A,
|
||
Delcroix M,
|
||
Rosenkranz S;
|
||
ESC/ERS Scientific Document Group</span><br />
|
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<span class="medgenPMjournal">Eur Heart J</span>
|
||
2022 Oct 11;43(38):3618-3731.
|
||
doi: 10.1093/eurheartj/ehac237.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36017548" target="_blank">36017548</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35412560">Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ruopp NF,
|
||
Cockrill BA</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2022 Apr 12;327(14):1379-1391.
|
||
doi: 10.1001/jama.2022.4402.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35412560" target="_blank">35412560</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32199055">Congenital heart disease, prenatal diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Meller CH,
|
||
Grinenco S,
|
||
Aiello H,
|
||
Córdoba A,
|
||
Sáenz-Tejeira MM,
|
||
Marantz P,
|
||
Otaño L</span><br />
|
||
<span class="medgenPMjournal">Arch Argent Pediatr</span>
|
||
2020 Apr;118(2):e149-e161.
|
||
doi: 10.5546/aap.2020.eng.e149.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32199055" target="_blank">32199055</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22congenital%20heart%20disease%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1534)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.acmg.net/PDFLibrary/CCHD-ACT-Sheet.pdf" target="_blank">American College of Medical Genetics and Genomics, Newborn Screening ACT Sheet, Hypoxemia, Critical Congenital Heart Disease, 2013</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37357777">Pulmonary Hypertension in Congenital Heart Disease: A Scientific Statement From the American Heart Association.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jone PN,
|
||
Ivy DD,
|
||
Hauck A,
|
||
Karamlou T,
|
||
Truong U,
|
||
Coleman RD,
|
||
Sandoval JP,
|
||
Del Cerro Marín MJ,
|
||
Eghtesady P,
|
||
Tillman K,
|
||
Krishnan US</span><br />
|
||
<span class="medgenPMjournal">Circ Heart Fail</span>
|
||
2023 Jul;16(7):e00080.
|
||
Epub 2023 Jun 26
|
||
doi: 10.1161/HHF.0000000000000080.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37357777" target="_blank">37357777</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28302743">Heart Failure in Pediatric Patients With Congenital Heart Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hinton RB,
|
||
Ware SM</span><br />
|
||
<span class="medgenPMjournal">Circ Res</span>
|
||
2017 Mar 17;120(6):978-994.
|
||
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<div class="portlet mgSection" id="ID_104">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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|
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<div class="nl"><a target="_blank" href="/pubmed/31070503">Congenital Heart Disease and Risk of Cardiovascular Disease: A Meta-Analysis of Cohort Studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang T,
|
||
Chen L,
|
||
Yang T,
|
||
Huang P,
|
||
Wang L,
|
||
Zhao L,
|
||
Zhang S,
|
||
Ye Z,
|
||
Chen L,
|
||
Zheng Z,
|
||
Qin J</span><br />
|
||
<span class="medgenPMjournal">J Am Heart Assoc</span>
|
||
2019 May 21;8(10):e012030.
|
||
doi: 10.1161/JAHA.119.012030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31070503" target="_blank">31070503</a><a href="/pmc/articles/PMC6585327" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30783674">Global birth prevalence of congenital heart defects 1970-2017: updated systematic review and meta-analysis of 260 studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu Y,
|
||
Chen S,
|
||
Zühlke L,
|
||
Black GC,
|
||
Choy MK,
|
||
Li N,
|
||
Keavney BD</span><br />
|
||
<span class="medgenPMjournal">Int J Epidemiol</span>
|
||
2019 Apr 1;48(2):455-463.
|
||
doi: 10.1093/ije/dyz009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30783674" target="_blank">30783674</a><a href="/pmc/articles/PMC6469300" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30586767">2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Stout KK,
|
||
Daniels CJ,
|
||
Aboulhosn JA,
|
||
Bozkurt B,
|
||
Broberg CS,
|
||
Colman JM,
|
||
Crumb SR,
|
||
Dearani JA,
|
||
Fuller S,
|
||
Gurvitz M,
|
||
Khairy P,
|
||
Landzberg MJ,
|
||
Saidi A,
|
||
Valente AM,
|
||
Van Hare GF</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2019 Apr 2;139(14):e698-e800.
|
||
doi: 10.1161/CIR.0000000000000603.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30586767" target="_blank">30586767</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22078432">Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">van der Linde D,
|
||
Konings EE,
|
||
Slager MA,
|
||
Witsenburg M,
|
||
Helbing WA,
|
||
Takkenberg JJ,
|
||
Roos-Hesselink JW</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Cardiol</span>
|
||
2011 Nov 15;58(21):2241-7.
|
||
doi: 10.1016/j.jacc.2011.08.025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22078432" target="_blank">22078432</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Congenital%20heart%20disease%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (410)</a></div></div>
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|
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|
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|
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|
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<div class="supplemental col three_col last">
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
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|
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|
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<!-- MedGen supplemental column starts here -->
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0152021%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (17)</a></li>
|
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<li><a href="/gtr/tests?term=C0152021%5bDISCUI%5d&filter=method%3A2%5F29" target="_blank">Detection of homozygosity (1)</a></li>
|
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<li><a href="/gtr/tests?term=C0152021%5bDISCUI%5d&filter=method%3A2%5F17" target="_blank">Mutation scanning of the entire coding region (4)</a></li>
|
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<li><a href="/gtr/tests?term=C0152021%5bDISCUI%5d&filter=method%3A2%5F9" target="_blank">Sequence analysis of select exons (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0152021%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (16)</a></li>
|
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<li><a href="/gtr/tests?term=C0152021%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (5)</a></li>
|
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0152021%5bDISCUI%5d" target="_blank">See all (21)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Congenital%20heart%20disease" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22congenital%20heart%20disease%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Congenital%20heart%20disease%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.acmg.net/PDFLibrary/CCHD-ACT-Sheet.pdf">ACMG ACT, 2013</a><div>American College of Medical Genetics and Genomics, Newborn Screening ACT Sheet, Hypoxemia, Critical Congenital Heart Disease, 2013</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="http://www.diseaseinfosearch.org/Congenital+Heart+Defects/1833" target="_blank">Genetic Alliance</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Congenital%20heart%20disease" target="_blank">MedlinePlus</a></li><li><a href="https://medlineplus.gov/genetics/condition/critical-congenital-heart-disease" target="_blank">MedlinePlusGenetics (GHR)</a></li></ul></div>
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