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<meta name="keywords" content="C0149925, carcinoma, small cell lung, lung oat cell carcinoma, lung small cell carcinoma, lung small cell neuroendocrine carcinoma, neoplastic process, oat cell carcinoma of lung, oat cell carcinoma of the lung, oat cell lung cancer, oat cell lung carcinoma, rb1, sccl, sclc, sclc - small cell lung cancer, sclc1, small cell cancer of the lung, small cell cancer of the lung, somatic, small cell carcinoma of lung, small cell carcinoma of the lung, small cell lung cancer, small cell lung carcinoma, small cell neuroendocrine carcinoma of lung, small cell neuroendocrine carcinoma of the lung, small-cell cancer of lung, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Small cell lung cancer (SCLC) is a type of highly malignant lung cancer that is composed of small ovoid cells. In the past, SCLC was called oat cell carcinoma because the microscopic appearance of the cells was felt to resemble oats. SLCLC usually originates near the bronchi and in many cases may grow and metastasize quickly." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=57450
|
||
ConceptID=C0149925
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Small cell lung carcinoma<span class="h1sub">(SCCL)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>57450</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0149925</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Lung oat cell carcinoma; SMALL CELL CANCER OF THE LUNG, SOMATIC; Small cell lung cancer</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Small cell carcinoma of lung (254632001); SCLC - Small cell lung cancer (254632001); Small cell lung cancer (254632001); Oat cell carcinoma of lung (254632001)</td></tr>
|
||
<tr><td>Modes of inheritance:</td>
|
||
<td>
|
||
<div class="divPopper rprt" id="moi_988794"><div><strong>Not genetically inherited</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>988794</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier assigned by MedGen (starting with CN) for terms that cannot be identified in NLM's Unified Medical Language system (UMLS) Click for more information.">CN307044</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Source: Orphanet</div>
|
||
<div class="spaceAbove">clinical entity without genetic inheritance.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/988794">This record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_988794" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Not genetically inherited</a><span> (Orphanet)</span></div></td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="RB1 - ID: 5925 - NCBI Gene" href="/gene/5925" class="medgenPMinfo">RB1</a> (13q14.2)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0030357">HP:0030357</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0008433" target="_blank">MONDO:0008433</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/182280" target="_blank">182280</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=70573">ORPHA70573</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
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<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Small cell lung cancer (SCLC) is a type of highly malignant lung cancer that is composed of small ovoid cells. In the past, SCLC was called oat cell carcinoma because the microscopic appearance of the cells was felt to resemble oats. SLCLC usually originates near the bronchi and in many cases may grow and metastasize quickly. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_7400"><div><strong>Neoplasm of lung</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>7400</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0024121</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Tumor of the lung.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/7400">Feature record</a> | <a href="/medgen?term=%22Neoplasm%20of%20lung%22%5BClinical%20Features%5D%20OR%207400%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite"><ul><li><span class="TLline">Neoplasm</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_7400" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neoplasm of lung</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0149925[DISCUI]&test_type=Clinical" ref="ncbi_uid=57450">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=57450" target="_blank" href="/omim/182280">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=57450" ref="ncbi_uid=57450">V</a></span></span><span class="TLline">Small cell lung carcinoma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/19750" ref="tree=MeSH" title="MedGen record for Disease, Respiratory Tract">Disease, Respiratory Tract</a></span><ul><li><span class="TLline"><a href="/medgen/14233" ref="tree=MeSH" title="MedGen record for Abnormality of the bronchi">Abnormality of the bronchi</a></span><ul><li><span class="TLline"><a href="/medgen/2735" ref="tree=MeSH" title="MedGen record for Bronchial neoplasm">Bronchial neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/2872" ref="tree=MeSH" title="MedGen record for Bronchogenic carcinoma">Bronchogenic carcinoma</a></span><ul><li><span class="matched_ds">Small cell lung carcinoma</span><ul><li><span class="TLline"><a href="/medgen/859235" ref="tree=MeSH" title="MedGen record for Childhood Lung Small Cell Carcinoma">Childhood Lung Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234167" ref="tree=MeSH" title="MedGen record for Combined small cell lung carcinoma">Combined small cell lung carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/231029" ref="tree=MeSH" title="MedGen record for Lung combined type small cell adenocarcinoma">Lung combined type small cell adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/235331" ref="tree=MeSH" title="MedGen record for Lung mixed small cell and squamous cell carcinoma">Lung mixed small cell and squamous cell carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124501" ref="tree=MeSH" title="MedGen record for Extensive Stage Lung Small Cell Carcinoma">Extensive Stage Lung Small Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1633456" ref="tree=MeSH" title="MedGen record for Recurrent Extensive Stage Lung Small Cell Carcinoma">Recurrent Extensive Stage Lung Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1643507" ref="tree=MeSH" title="MedGen record for Refractory Extensive Stage Lung Small Cell Carcinoma">Refractory Extensive Stage Lung Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/236888" ref="tree=MeSH" title="MedGen record for Stage IIIB Lung Small Cell Carcinoma with Pleural Effusion AJCC v7">Stage IIIB Lung Small Cell Carcinoma with Pleural Effusion AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/236943" ref="tree=MeSH" title="MedGen record for Stage IV Lung Small Cell Carcinoma AJCC v7">Stage IV Lung Small Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/75862" ref="tree=MeSH" title="MedGen record for Limited Stage Lung Small Cell Carcinoma">Limited Stage Lung Small Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/277765" ref="tree=MeSH" title="MedGen record for Stage I Lung Small Cell Carcinoma AJCC v7">Stage I Lung Small Cell Carcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/233479" ref="tree=MeSH" title="MedGen record for Stage IA Lung Small Cell Carcinoma AJCC v7">Stage IA Lung Small Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/233483" ref="tree=MeSH" title="MedGen record for Stage IB Lung Small Cell Carcinoma AJCC v7">Stage IB Lung Small Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/277726" ref="tree=MeSH" title="MedGen record for Stage II Lung Small Cell Carcinoma AJCC v7">Stage II Lung Small Cell Carcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/233487" ref="tree=MeSH" title="MedGen record for Stage IIA Lung Small Cell Carcinoma AJCC v7">Stage IIA Lung Small Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/234833" ref="tree=MeSH" title="MedGen record for Stage IIB Lung Small Cell Carcinoma AJCC v7">Stage IIB Lung Small Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233493" ref="tree=MeSH" title="MedGen record for Stage IIIA Lung Small Cell Carcinoma AJCC v7">Stage IIIA Lung Small Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/277705" ref="tree=MeSH" title="MedGen record for Stage IIIB Lung Small Cell Carcinoma without Pleural Effusion AJCC v7">Stage IIIB Lung Small Cell Carcinoma without Pleural Effusion AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1619815" ref="tree=MeSH" title="MedGen record for Lung Small Cell Carcinoma by AJCC v7 Stage">Lung Small Cell Carcinoma by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/236899" ref="tree=MeSH" title="MedGen record for Stage III Lung Small Cell Carcinoma AJCC v7">Stage III Lung Small Cell Carcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/277704" ref="tree=MeSH" title="MedGen record for Stage IIIB Lung Small Cell Carcinoma AJCC v7">Stage IIIB Lung Small Cell Carcinoma AJCC v7</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1664088" ref="tree=MeSH" title="MedGen record for Metastatic Lung Small Cell Carcinoma">Metastatic Lung Small Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1705311" ref="tree=MeSH" title="MedGen record for Advanced Lung Small Cell Carcinoma">Advanced Lung Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1784772" ref="tree=MeSH" title="MedGen record for Locally Advanced Lung Small Cell Carcinoma">Locally Advanced Lung Small Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233791" ref="tree=MeSH" title="MedGen record for Occult small cell lung carcinoma">Occult small cell lung carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1683050" ref="tree=MeSH" title="MedGen record for Platinum-Sensitive Lung Small Cell Carcinoma">Platinum-Sensitive Lung Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/75863" ref="tree=MeSH" title="MedGen record for Recurrent Lung Small Cell Carcinoma">Recurrent Lung Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1662162" ref="tree=MeSH" title="MedGen record for Refractory Lung Small Cell Carcinoma">Refractory Lung Small Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1679488" ref="tree=MeSH" title="MedGen record for Platinum-Resistant Lung Small Cell Carcinoma">Platinum-Resistant Lung Small Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1701768" ref="tree=MeSH" title="MedGen record for Unresectable Lung Small Cell Carcinoma">Unresectable Lung Small Cell Carcinoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=10953&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Small cell lung carcinoma</span> in Orphanet.</div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38684283">Oral targeted therapy for the treatment of non-small cell lung carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Phillips WJ,
|
||
Leighl NB,
|
||
Blais N,
|
||
Wheatley-Price P</span><br />
|
||
<span class="medgenPMjournal">CMAJ</span>
|
||
2024 Apr 28;196(16):E558-E561.
|
||
doi: 10.1503/cmaj.231562.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38684283" target="_blank">38684283</a><a href="/pmc/articles/PMC11057882" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34932393">Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vogelbaum MA,
|
||
Brown PD,
|
||
Messersmith H,
|
||
Brastianos PK,
|
||
Burri S,
|
||
Cahill D,
|
||
Dunn IF,
|
||
Gaspar LE,
|
||
Gatson NTN,
|
||
Gondi V,
|
||
Jordan JT,
|
||
Lassman AB,
|
||
Maues J,
|
||
Mohile N,
|
||
Redjal N,
|
||
Stevens G,
|
||
Sulman E,
|
||
van den Bent M,
|
||
Wallace HJ,
|
||
Weinberg JS,
|
||
Zadeh G,
|
||
Schiff D</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2022 Feb 10;40(5):492-516.
|
||
Epub 2021 Dec 21
|
||
doi: 10.1200/JCO.21.02314.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34932393" target="_blank">34932393</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33435596">Treatment of Brain Metastases of Non-Small Cell Lung Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rybarczyk-Kasiuchnicz A,
|
||
Ramlau R,
|
||
Stencel K</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2021 Jan 8;22(2)
|
||
doi: 10.3390/ijms22020593.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33435596" target="_blank">33435596</a><a href="/pmc/articles/PMC7826874" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22small%20cell%20lung%20carcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (294)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/sclc.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Small Cell Lung Cancer, 2023</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng122" target="_blank">UK NICE guideline NG122, Lung cancer: diagnosis and management, 2023</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.cms.gov/Medicare/Coverage/DeterminationProcess/downloads/id90TA.pdf" target="_blank">Technology Assessment on Genetic Testing or Molecular Pathology Testing of Cancers with Unknown Primary Site to Determine Origin (ARCHIVED)</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36243387">SCLC: Epidemiology, Risk Factors, Genetic Susceptibility, Molecular Pathology, Screening, and Early Detection.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Q,
|
||
Gümüş ZH,
|
||
Colarossi C,
|
||
Memeo L,
|
||
Wang X,
|
||
Kong CY,
|
||
Boffetta P</span><br />
|
||
<span class="medgenPMjournal">J Thorac Oncol</span>
|
||
2023 Jan;18(1):31-46.
|
||
Epub 2022 Oct 12
|
||
doi: 10.1016/j.jtho.2022.10.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36243387" target="_blank">36243387</a><a href="/pmc/articles/PMC10797993" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34953709">Radiotherapy for primary lung cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khalifa J,
|
||
Lerouge D,
|
||
Le Péchoux C,
|
||
Pourel N,
|
||
Darréon J,
|
||
Mornex F,
|
||
Giraud P</span><br />
|
||
<span class="medgenPMjournal">Cancer Radiother</span>
|
||
2022 Feb-Apr;26(1-2):231-243.
|
||
Epub 2021 Dec 22
|
||
doi: 10.1016/j.canrad.2021.11.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34953709" target="_blank">34953709</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34908517">Lung Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lareau S,
|
||
Slatore C,
|
||
Smyth R</span><br />
|
||
<span class="medgenPMjournal">Am J Respir Crit Care Med</span>
|
||
2021 Dec 15;204(12):P21-P22.
|
||
doi: 10.1164/rccm.20411P21.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34908517" target="_blank">34908517</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33864941">Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up(☆).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dingemans AC,
|
||
Früh M,
|
||
Ardizzoni A,
|
||
Besse B,
|
||
Faivre-Finn C,
|
||
Hendriks LE,
|
||
Lantuejoul S,
|
||
Peters S,
|
||
Reguart N,
|
||
Rudin CM,
|
||
De Ruysscher D,
|
||
Van Schil PE,
|
||
Vansteenkiste J,
|
||
Reck M;
|
||
ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org</span><br />
|
||
<span class="medgenPMjournal">Ann Oncol</span>
|
||
2021 Jul;32(7):839-853.
|
||
Epub 2021 Apr 20
|
||
doi: 10.1016/j.annonc.2021.03.207.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33864941" target="_blank">33864941</a><a href="/pmc/articles/PMC9464246" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20045787">Lung Cancer OncoGuia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lung Cancer OncoGuia Group,
|
||
Manchon Walsh P,
|
||
Manchon P,
|
||
Borràs JM,
|
||
Ferro T,
|
||
Espinàs JA</span><br />
|
||
<span class="medgenPMjournal">Clin Transl Oncol</span>
|
||
2009 Dec;11(12):805-24.
|
||
doi: 10.1007/s12094-009-0449-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20045787" target="_blank">20045787</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20cell%20lung%20carcinoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4361)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36243387">SCLC: Epidemiology, Risk Factors, Genetic Susceptibility, Molecular Pathology, Screening, and Early Detection.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Q,
|
||
Gümüş ZH,
|
||
Colarossi C,
|
||
Memeo L,
|
||
Wang X,
|
||
Kong CY,
|
||
Boffetta P</span><br />
|
||
<span class="medgenPMjournal">J Thorac Oncol</span>
|
||
2023 Jan;18(1):31-46.
|
||
Epub 2022 Oct 12
|
||
doi: 10.1016/j.jtho.2022.10.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36243387" target="_blank">36243387</a><a href="/pmc/articles/PMC10797993" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34663914">Lung neuroendocrine neoplasms: recent progress and persistent challenges.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rekhtman N</span><br />
|
||
<span class="medgenPMjournal">Mod Pathol</span>
|
||
2022 Jan;35(Suppl 1):36-50.
|
||
Epub 2021 Oct 18
|
||
doi: 10.1038/s41379-021-00943-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34663914" target="_blank">34663914</a><a href="/pmc/articles/PMC8695375" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34273294">Lung cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Thai AA,
|
||
Solomon BJ,
|
||
Sequist LV,
|
||
Gainor JF,
|
||
Heist RS</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2021 Aug 7;398(10299):535-554.
|
||
Epub 2021 Jul 21
|
||
doi: 10.1016/S0140-6736(21)00312-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34273294" target="_blank">34273294</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33864941">Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up(☆).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dingemans AC,
|
||
Früh M,
|
||
Ardizzoni A,
|
||
Besse B,
|
||
Faivre-Finn C,
|
||
Hendriks LE,
|
||
Lantuejoul S,
|
||
Peters S,
|
||
Reguart N,
|
||
Rudin CM,
|
||
De Ruysscher D,
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<div class="nl"><a target="_blank" href="/pubmed/21565397">Small-cell lung cancer.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/34932393">Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Vogelbaum MA,
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Brown PD,
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<div class="nl"><a target="_blank" href="/pubmed/31590988">Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial.</a></div>
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<span class="medgenPMjournal">Lancet</span>
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<div class="nl"><a target="_blank" href="/pubmed/31046803">Emerging therapies for small cell lung cancer.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Yang S,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20cell%20lung%20carcinoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4279)</a></div><h3 class="subhead">Prognosis</h3>
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<span class="medgenPMjournal">Ann Oncol</span>
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Epub 2021 Apr 20
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<span class="bold">PMID: </span><a href="/pubmed/33864941" target="_blank">33864941</a><a href="/pmc/articles/PMC9464246" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/33662285">High-dose versus standard-dose twice-daily thoracic radiotherapy for patients with limited stage small-cell lung cancer: an open-label, randomised, phase 2 trial.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28642008">Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial.</a></div>
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<span class="medgenPMjournal">Lancet Oncol</span>
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<div class="nl"><a target="_blank" href="/pubmed/27912830">Advances in Small Cell Lung Cancer.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20cell%20lung%20carcinoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4850)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/36661372">An Autoantibody Subset Can Be Used for SCLC Early Detection.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/36520421">Emerging Strategies for the Treatment of Small Cell Lung Cancer: A Review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Petty WJ,
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<span class="bold">PMID: </span><a href="/pubmed/36520421" target="_blank">36520421</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/34041615">The efficacy of music therapy to relieve pain, anxiety, and promote sleep quality, in patients with small cell lung cancer receiving platinum-based chemotherapy.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Tang H,
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Chen L,
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<span class="medgenPMjournal">Support Care Cancer</span>
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2021 Dec;29(12):7299-7306.
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<span class="bold">PMID: </span><a href="/pubmed/34041615" target="_blank">34041615</a></div>
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Nambirajan A,
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<div class="nl"><a target="_blank" href="/pubmed/23885909">Personalized oncology in interventional radiology.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Abi-Jaoudeh N,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20cell%20lung%20carcinoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3968)</a></div></div>
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</div>
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<div class="portlet mgSection" id="ID_104">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
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<div class="nl"><a target="_blank" href="/pubmed/38625698">Neoadjuvant Chemo-Immunotherapy for Early-Stage Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Banna GL,
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Hassan MA,
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Signori A,
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Giunta EF,
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Maniam A,
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Anpalakhan S,
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Acharige S,
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Ghose A,
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Addeo A</span><br />
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<span class="medgenPMjournal">JAMA Netw Open</span>
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2024 Apr 1;7(4):e246837.
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<span class="bold">PMID: </span><a href="/pubmed/38625698" target="_blank">38625698</a><a href="/pmc/articles/PMC11022115" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/37948842">Systematic review and meta-analysis of immune checkpoint inhibitors as single agent or in combination with chemotherapy in early-stage non-small cell lung cancer: Impact of clinicopathological factors and indirect comparison between treatment strategies.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Nuccio A,
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Viscardi G,
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Salomone F,
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Servetto A,
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Venanzi FM,
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Riva ST,
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Oresti S,
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Ogliari FR,
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Viganò M,
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Bulotta A,
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Cameron R,
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Esposito A,
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Hines J,
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Bianco R,
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Reni M,
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Cascone T,
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Garassino MC,
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Torri V,
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Veronesi G,
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<span class="bold">PMID: </span><a href="/pubmed/37948842" target="_blank">37948842</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/35644163">Stereotactic radiosurgery versus whole brain radiotherapy in patients with intracranial metastatic disease and small-cell lung cancer: a systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gaebe K,
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Li AY,
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Park A,
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Parmar A,
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Lok BH,
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<span class="medgenPMjournal">Lancet Oncol</span>
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2022 Jul;23(7):931-939.
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<span class="bold">PMID: </span><a href="/pubmed/35644163" target="_blank">35644163</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/34932393">Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Vogelbaum MA,
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Brown PD,
|
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Messersmith H,
|
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Brastianos PK,
|
||
Burri S,
|
||
Cahill D,
|
||
Dunn IF,
|
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Gaspar LE,
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Gatson NTN,
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Gondi V,
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Jordan JT,
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Lassman AB,
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Maues J,
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Mohile N,
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Redjal N,
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Stevens G,
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Sulman E,
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van den Bent M,
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Wallace HJ,
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Weinberg JS,
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Zadeh G,
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Schiff D</span><br />
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<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2022 Feb 10;40(5):492-516.
|
||
Epub 2021 Dec 21
|
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doi: 10.1200/JCO.21.02314.
|
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<span class="bold">PMID: </span><a href="/pubmed/34932393" target="_blank">34932393</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28499515">Incidence of Pneumonitis With Use of Programmed Death 1 and Programmed Death-Ligand 1 Inhibitors in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis of Trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khunger M,
|
||
Rakshit S,
|
||
Pasupuleti V,
|
||
Hernandez AV,
|
||
Mazzone P,
|
||
Stevenson J,
|
||
Pennell NA,
|
||
Velcheti V</span><br />
|
||
<span class="medgenPMjournal">Chest</span>
|
||
2017 Aug;152(2):271-281.
|
||
Epub 2017 May 10
|
||
doi: 10.1016/j.chest.2017.04.177.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28499515" target="_blank">28499515</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20cell%20lung%20carcinoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (178)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
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<div class=" bottom">
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</div>
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</div>
|
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<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
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|
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|
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<div class="rightCol mgCol">
|
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul id="my-toc"></ul></div>
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|
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0149925%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (24)</a></li>
|
||
<li><a href="/gtr/tests?term=C0149925%5bDISCUI%5d&filter=method%3A2%5F30" target="_blank">RNA analysis (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C0149925%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (25)</a></li>
|
||
<li><a href="/gtr/tests?term=C0149925%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (5)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0149925%5bDISCUI%5d" target="_blank">See all (33)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=182280" target="_blank">OMIM</a></li><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=70573" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Small%20cell%20lung%20carcinoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
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</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22small%20cell%20lung%20carcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Small%20cell%20lung%20carcinoma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/sclc.pdf">NCCN, 2023</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Small Cell Lung Cancer, 2023</div></li><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng122">NICE, 2023</a><div>UK NICE guideline NG122, Lung cancer: diagnosis and management, 2023</div></li><li><a target="_blank" href="https://www.cms.gov/Medicare/Coverage/DeterminationProcess/downloads/id90TA.pdf">AHRQ, 2013</a><div>Technology Assessment on Genetic Testing or Molecular Pathology Testing of Cancers with Unknown Primary Site to Determine Origin (ARCHIVED)</div></li></ul></div>
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