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<meta name="keywords" content="C0004134, ataxia, ataxia (loss of muscle coordination), ataxia,, ataxias, ataxy, coordination impairment, coordination impairments, dyssynergia, impairment, coordination, impairments, coordination, sign or symptom, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A type of ataxia characterized by the impairment of the ability to smoothly perform the elements of a voluntary movement in the appropriate order and speed. With dyssynergia, a voluntary movement appears broken down into its component parts." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Dyssynergia (Concept Id: C0004134)
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<!--
UID=13945
ConceptID=C0004134
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Dyssynergia</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>13945</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C0004134</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Sign or Symptom</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>Ataxia</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Ataxia (loss of muscle coordination) (20262006); Ataxia (20262006); Dyssynergia (39384006)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0010867">HP:0010867</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A type of ataxia characterized by the impairment of the ability to smoothly perform the elements of a voluntary movement in the appropriate order and speed. With dyssynergia, a voluntary movement appears broken down into its component parts. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0004134[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=13945">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=13945" ref="ncbi_uid=13945">V</a></span></span><span class="TLline">Dyssynergia</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/474891" ref="tree=MeSH" title="MedGen record for Congenital Systemic Disorder">Congenital Systemic Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/105425" ref="tree=MeSH" title="MedGen record for Abnormality of the nervous system">Abnormality of the nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/868417" ref="tree=MeSH" title="MedGen record for Abnormal nervous system physiology">Abnormal nervous system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/868940" ref="tree=MeSH" title="MedGen record for Abnormal central motor function">Abnormal central motor function</a></span><ul><li><span class="TLline"><a href="/medgen/868939" ref="tree=MeSH" title="MedGen record for Abnormality of coordination">Abnormality of coordination</a></span><ul><li><span class="TLline"><a href="/medgen/849" ref="tree=MeSH" title="MedGen record for Cerebellar ataxia">Cerebellar ataxia</a></span><ul><li><span class="matched_ds">Dyssynergia</span><ul><li><span class="TLline"><a href="/medgen/451003" ref="tree=MeSH" title="MedGen record for Asynergia">Asynergia</a></span></li><li><span class="TLline"><a href="/medgen/849" ref="tree=MeSH" title="MedGen record for Cerebellar ataxia">Cerebellar ataxia</a></span><ul><li><span class="TLline"><a href="/medgen/115975" ref="tree=MeSH" title="MedGen record for Dysdiadochokinesis">Dysdiadochokinesis</a></span></li><li><span class="TLline"><a href="/medgen/68583" ref="tree=MeSH" title="MedGen record for Dysmetria">Dysmetria</a></span><ul><li><span class="TLline"><a href="/medgen/340244" ref="tree=MeSH" title="MedGen record for Limb dysmetria">Limb dysmetria</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/314033" ref="tree=MeSH" title="MedGen record for Hereditary episodic ataxia">Hereditary episodic ataxia</a></span><ul><li><span class="TLline"><a href="/medgen/318554" ref="tree=MeSH" title="MedGen record for Episodic ataxia type 1">Episodic ataxia type 1</a></span></li><li><span class="TLline"><a href="/medgen/314039" ref="tree=MeSH" title="MedGen record for Episodic ataxia type 2">Episodic ataxia type 2</a></span></li><li><span class="TLline"><a href="/medgen/376220" ref="tree=MeSH" title="MedGen record for Episodic ataxia type 3">Episodic ataxia type 3</a></span></li><li><span class="TLline"><a href="/medgen/376222" ref="tree=MeSH" title="MedGen record for Episodic ataxia type 4">Episodic ataxia type 4</a></span></li><li><span class="TLline"><a href="/medgen/356142" ref="tree=MeSH" title="MedGen record for Episodic ataxia type 5">Episodic ataxia type 5</a></span></li><li><span class="TLline"><a href="/medgen/390739" ref="tree=MeSH" title="MedGen record for Episodic ataxia type 6">Episodic ataxia type 6</a></span></li><li><span class="TLline"><a href="/medgen/383209" ref="tree=MeSH" title="MedGen record for Episodic ataxia type 7">Episodic ataxia type 7</a></span></li><li><span class="TLline"><a href="/medgen/863545" ref="tree=MeSH" title="MedGen record for Episodic ataxia type 8">Episodic ataxia type 8</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/196692" ref="tree=MeSH" title="MedGen record for Limb ataxia">Limb ataxia</a></span></li><li><span class="TLline"><a href="/medgen/335079" ref="tree=MeSH" title="MedGen record for Nonprogressive cerebellar ataxia">Nonprogressive cerebellar ataxia</a></span></li><li><span class="TLline"><a href="/medgen/1635801" ref="tree=MeSH" title="MedGen record for Optic ataxia">Optic ataxia</a></span></li><li><span class="TLline"><a href="/medgen/140727" ref="tree=MeSH" title="MedGen record for Progressive cerebellar ataxia">Progressive cerebellar ataxia</a></span></li><li><span class="TLline"><a href="/medgen/376528" ref="tree=MeSH" title="MedGen record for Spastic ataxia">Spastic ataxia</a></span><ul><li><span class="TLline"><a href="/medgen/905660" ref="tree=MeSH" title="MedGen record for Spasticity-ataxia-gait anomalies syndrome">Spasticity-ataxia-gait anomalies syndrome</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/39733" ref="tree=MeSH" title="MedGen record for Spinocerebellar atrophy">Spinocerebellar atrophy</a></span><ul><li><span class="TLline"><a href="/medgen/767604" ref="tree=MeSH" title="MedGen record for Ataxia with oculomotor apraxia type 3">Ataxia with oculomotor apraxia type 3</a></span></li><li><span class="TLline"><a href="/medgen/395301" ref="tree=MeSH" title="MedGen record for Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia">Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia</a></span></li><li><span class="TLline"><a href="/medgen/439" ref="tree=MeSH" title="MedGen record for Ataxia-telangiectasia syndrome">Ataxia-telangiectasia syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1684639" ref="tree=MeSH" title="MedGen record for Autosomal dominant cerebellar ataxia">Autosomal dominant cerebellar ataxia</a></span></li><li><span class="TLline"><a href="/medgen/1843058" ref="tree=MeSH" title="MedGen record for Autosomal recessive cerebellar ataxia">Autosomal recessive cerebellar ataxia</a></span></li><li><span class="TLline"><a href="/medgen/9841" ref="tree=MeSH" title="MedGen record for Azorean disease">Azorean disease</a></span></li><li><span class="TLline"><a href="/medgen/341248" ref="tree=MeSH" title="MedGen record for Familial isolated deficiency of vitamin E">Familial isolated deficiency of vitamin E</a></span></li><li><span class="TLline"><a href="/medgen/156006" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia 7">Spinocerebellar ataxia 7</a></span></li><li><span class="TLline"><a href="/medgen/155703" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 1">Spinocerebellar ataxia type 1</a></span></li><li><span class="TLline"><a href="/medgen/155704" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 2">Spinocerebellar ataxia type 2</a></span></li><li><span class="TLline"><a href="/medgen/148458" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 6">Spinocerebellar ataxia type 6</a></span></li><li><span class="TLline"><a href="/medgen/347653" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 12">Spinocerebellar ataxia type 12</a></span></li><li><span class="TLline"><a href="/medgen/337637" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 17">Spinocerebellar ataxia type 17</a></span></li><li><span class="TLline"><a href="/medgen/1711119" ref="tree=MeSH" title="MedGen record for Spinocerebellar Ataxia Type 19/22">Spinocerebellar Ataxia Type 19/22</a></span></li><li><span class="TLline"><a href="/medgen/348439" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 31">Spinocerebellar ataxia type 31</a></span></li><li><span class="TLline"><a href="/medgen/483339" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 36">Spinocerebellar ataxia type 36</a></span></li><li><span class="TLline"><a href="/medgen/902592" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 42">Spinocerebellar ataxia type 42</a></span></li><li><span class="TLline"><a href="/medgen/340052" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2">Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/96535" ref="tree=MeSH" title="MedGen record for Truncal ataxia">Truncal ataxia</a></span><ul><li><span class="TLline"><a href="/medgen/341389" ref="tree=MeSH" title="MedGen record for Progressive truncal ataxia">Progressive truncal ataxia</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/338620" ref="tree=MeSH" title="MedGen record for Charlevoix-Saguenay spastic ataxia">Charlevoix-Saguenay spastic ataxia</a></span></li><li><span class="TLline"><a href="/medgen/1726347" ref="tree=MeSH" title="MedGen record for COVID-19-Associated Ataxia">COVID-19-Associated Ataxia</a></span></li><li><span class="TLline"><a href="/medgen/155642" ref="tree=MeSH" title="MedGen record for Gait ataxia">Gait ataxia</a></span><ul><li><span class="TLline"><a href="/medgen/776653" ref="tree=MeSH" title="MedGen record for Abasia">Abasia</a></span></li><li><span class="TLline"><a href="/medgen/375309" ref="tree=MeSH" title="MedGen record for Progressive gait ataxia">Progressive gait ataxia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/78726" ref="tree=MeSH" title="MedGen record for Hereditary cerebellar ataxia">Hereditary cerebellar ataxia</a></span><ul><li><span class="TLline"><a href="/medgen/5276" ref="tree=MeSH" title="MedGen record for Friedreich ataxia">Friedreich ataxia</a></span><ul><li><span class="TLline"><a href="/medgen/383962" ref="tree=MeSH" title="MedGen record for Friedreich ataxia 1">Friedreich ataxia 1</a></span></li><li><span class="TLline"><a href="/medgen/356134" ref="tree=MeSH" title="MedGen record for Friedreich ataxia 2">Friedreich ataxia 2</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/869256" ref="tree=MeSH" title="MedGen record for Ocular dyssynergia">Ocular dyssynergia</a></span></li><li><span class="TLline"><a href="/medgen/370750" ref="tree=MeSH" title="MedGen record for Spastic ataxia 2">Spastic ataxia 2</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/37452811">AGA Clinical Practice Update on Evaluation and Management of Belching, Abdominal Bloating, and Distention: Expert Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Moshiree B,
Drossman D,
Shaukat A</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2023 Sep;165(3):791-800.e3.
Epub 2023 Jul 13
doi: 10.1053/j.gastro.2023.04.039.
<span class="bold">PMID: </span><a href="/pubmed/37452811" target="_blank">37452811</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36729157">Pathophysiological basis, clinical assessment, investigation and management of patients with obstruction defecation syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bunni J,
Laugharne MJ</span><br />
<span class="medgenPMjournal">Langenbecks Arch Surg</span>
2023 Feb 2;408(1):75.
doi: 10.1007/s00423-023-02755-1.
<span class="bold">PMID: </span><a href="/pubmed/36729157" target="_blank">36729157</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31407463">The international anorectal physiology working group (IAPWG) recommendations: Standardized testing protocol and the London classification for disorders of anorectal function.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Carrington EV,
Heinrich H,
Knowles CH,
Fox M,
Rao S,
Altomare DF,
Bharucha AE,
Burgell R,
Chey WD,
Chiarioni G,
Dinning P,
Emmanuel A,
Farouk R,
Felt-Bersma RJF,
Jung KW,
Lembo A,
Malcolm A,
Mittal RK,
Mion F,
Myung SJ,
O'Connell PR,
Pehl C,
Remes-Troche JM,
Reveille RM,
Vaizey CJ,
Vitton V,
Whitehead WE,
Wong RK,
Scott SM;
All members of the International Anorectal Physiology Working Group</span><br />
<span class="medgenPMjournal">Neurogastroenterol Motil</span>
2020 Jan;32(1):e13679.
Epub 2019 Aug 12
doi: 10.1111/nmo.13679.
<span class="bold">PMID: </span><a href="/pubmed/31407463" target="_blank">31407463</a><a href="/pmc/articles/PMC6923590" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22dyssynergia%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (97)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37452811">AGA Clinical Practice Update on Evaluation and Management of Belching, Abdominal Bloating, and Distention: Expert Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Moshiree B,
Drossman D,
Shaukat A</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2023 Sep;165(3):791-800.e3.
Epub 2023 Jul 13
doi: 10.1053/j.gastro.2023.04.039.
<span class="bold">PMID: </span><a href="/pubmed/37452811" target="_blank">37452811</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29752515">Epidemiology and pathophysiology of neurogenic bladder after spinal cord injury.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Hamid R,
Averbeck MA,
Chiang H,
Garcia A,
Al Mousa RT,
Oh SJ,
Patel A,
Plata M,
Del Popolo G</span><br />
<span class="medgenPMjournal">World J Urol</span>
2018 Oct;36(10):1517-1527.
Epub 2018 May 11
doi: 10.1007/s00345-018-2301-z.
<span class="bold">PMID: </span><a href="/pubmed/29752515" target="_blank">29752515</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29072046">Diagnosis and clinical evaluation of neurogenic bladder.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Amarenco G,
Sheikh Ismaël S,
Chesnel C,
Charlanes A,
LE Breton F</span><br />
<span class="medgenPMjournal">Eur J Phys Rehabil Med</span>
2017 Dec;53(6):975-980.
Epub 2017 Oct 25
doi: 10.23736/S1973-9087.17.04992-9.
<span class="bold">PMID: </span><a href="/pubmed/29072046" target="_blank">29072046</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26826587">Detrusor-External Sphincter Dyssynergia: Review of Minimally Invasive and Endoscopic Management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Barbalat Y,
Rutman M</span><br />
<span class="medgenPMjournal">Urology</span>
2016 Apr;90:3-7.
Epub 2016 Jan 27
doi: 10.1016/j.urology.2015.11.049.
<span class="bold">PMID: </span><a href="/pubmed/26826587" target="_blank">26826587</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9440859">Role of permanent stents.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Badlani GH</span><br />
<span class="medgenPMjournal">J Endourol</span>
1997 Dec;11(6):473-5.
doi: 10.1089/end.1997.11.473.
<span class="bold">PMID: </span><a href="/pubmed/9440859" target="_blank">9440859</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dyssynergia%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (483)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37452811">AGA Clinical Practice Update on Evaluation and Management of Belching, Abdominal Bloating, and Distention: Expert Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Moshiree B,
Drossman D,
Shaukat A</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2023 Sep;165(3):791-800.e3.
Epub 2023 Jul 13
doi: 10.1053/j.gastro.2023.04.039.
<span class="bold">PMID: </span><a href="/pubmed/37452811" target="_blank">37452811</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33060396">Solitary rectal ulcer syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Felt-Bersma RJF</span><br />
<span class="medgenPMjournal">Curr Opin Gastroenterol</span>
2021 Jan;37(1):59-65.
doi: 10.1097/MOG.0000000000000689.
<span class="bold">PMID: </span><a href="/pubmed/33060396" target="_blank">33060396</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32718574">Refractory Constipation: How to Evaluate and Treat.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Camilleri M,
Brandler J</span><br />
<span class="medgenPMjournal">Gastroenterol Clin North Am</span>
2020 Sep;49(3):623-642.
Epub 2020 Jun 14
doi: 10.1016/j.gtc.2020.05.002.
<span class="bold">PMID: </span><a href="/pubmed/32718574" target="_blank">32718574</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29072046">Diagnosis and clinical evaluation of neurogenic bladder.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Amarenco G,
Sheikh Ismaël S,
Chesnel C,
Charlanes A,
LE Breton F</span><br />
<span class="medgenPMjournal">Eur J Phys Rehabil Med</span>
2017 Dec;53(6):975-980.
Epub 2017 Oct 25
doi: 10.23736/S1973-9087.17.04992-9.
<span class="bold">PMID: </span><a href="/pubmed/29072046" target="_blank">29072046</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28645341">Spinocerebellar Ataxia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wentz S,
Jusufbegovic D</span><br />
<span class="medgenPMjournal">Ophthalmology</span>
2017 Jul;124(7):1071.
doi: 10.1016/j.ophtha.2017.01.019.
<span class="bold">PMID: </span><a href="/pubmed/28645341" target="_blank">28645341</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dyssynergia%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (430)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/33737146">Non-pharmacologic approach to pediatric constipation.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Santucci NR,
Chogle A,
Leiby A,
Mascarenhas M,
Borlack RE,
Lee A,
Perez M,
Russell A,
Yeh AM</span><br />
<span class="medgenPMjournal">Complement Ther Med</span>
2021 Jun;59:102711.
Epub 2021 Mar 15
doi: 10.1016/j.ctim.2021.102711.
<span class="bold">PMID: </span><a href="/pubmed/33737146" target="_blank">33737146</a></div>
<div class="nl"><a target="_blank" href="/pubmed/16477480">Botulinum toxin in multiple sclerosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jost WH</span><br />
<span class="medgenPMjournal">J Neurol</span>
2006 Feb;253 Suppl 1:I16-20.
doi: 10.1007/s00415-006-1104-0.
<span class="bold">PMID: </span><a href="/pubmed/16477480" target="_blank">16477480</a></div>
<div class="nl"><a target="_blank" href="/pubmed/15679792">Urethral stents for detrusor sphincter dyssynergia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nambirajan T,
Woolsey S,
Mahendra V,
Stone AR,
Walsh IK</span><br />
<span class="medgenPMjournal">BJU Int</span>
2005 Feb;95(3):350-3.
doi: 10.1111/j.1464-410X.2005.05298.x.
<span class="bold">PMID: </span><a href="/pubmed/15679792" target="_blank">15679792</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9440859">Role of permanent stents.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Badlani GH</span><br />
<span class="medgenPMjournal">J Endourol</span>
1997 Dec;11(6):473-5.
doi: 10.1089/end.1997.11.473.
<span class="bold">PMID: </span><a href="/pubmed/9440859" target="_blank">9440859</a></div>
<div class="nl"><a target="_blank" href="/pubmed/458950">Detrusor-sphincter dyssynergia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">McGuire EJ,
Brady S</span><br />
<span class="medgenPMjournal">J Urol</span>
1979 Jun;121(6):774-7.
doi: 10.1016/s0022-5347(17)56987-6.
<span class="bold">PMID: </span><a href="/pubmed/458950" target="_blank">458950</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dyssynergia%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (326)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37579786">Constipation in Parkinson's Disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Quigley EMM</span><br />
<span class="medgenPMjournal">Semin Neurol</span>
2023 Aug;43(4):562-571.
Epub 2023 Aug 14
doi: 10.1055/s-0043-1771457.
<span class="bold">PMID: </span><a href="/pubmed/37579786" target="_blank">37579786</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36401758">Video-Based Deep Learning to Detect Dyssynergic Defecation with 3D High-Definition Anorectal Manometry.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Levy JJ,
Navas CM,
Chandra JA,
Christensen BC,
Vaickus LJ,
Curley M,
Chey WD,
Baker JR,
Shah ED</span><br />
<span class="medgenPMjournal">Dig Dis Sci</span>
2023 May;68(5):2015-2022.
Epub 2022 Nov 19
doi: 10.1007/s10620-022-07759-3.
<span class="bold">PMID: </span><a href="/pubmed/36401758" target="_blank">36401758</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26003255">Lower urinary tract dysfunction in patients with multiple sclerosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Panicker JN,
Fowler CJ</span><br />
<span class="medgenPMjournal">Handb Clin Neurol</span>
2015;130:371-81.
doi: 10.1016/B978-0-444-63247-0.00021-3.
<span class="bold">PMID: </span><a href="/pubmed/26003255" target="_blank">26003255</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9440859">Role of permanent stents.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Badlani GH</span><br />
<span class="medgenPMjournal">J Endourol</span>
1997 Dec;11(6):473-5.
doi: 10.1089/end.1997.11.473.
<span class="bold">PMID: </span><a href="/pubmed/9440859" target="_blank">9440859</a></div>
<div class="nl"><a target="_blank" href="/pubmed/1970915">Female urinary retention.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wheeler JS Jr,
Culkin DJ,
Walter JS,
Flanigan RC</span><br />
<span class="medgenPMjournal">Urology</span>
1990 May;35(5):428-32.
doi: 10.1016/0090-4295(90)80086-3.
<span class="bold">PMID: </span><a href="/pubmed/1970915" target="_blank">1970915</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dyssynergia%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (252)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/38467383">Thoracoabdominal Wall Motion-Guided Biofeedback Treatment of Abdominal Distention: A Randomized Placebo-Controlled Trial.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Barba E,
Livovsky DM,
Accarino A,
Azpiroz F</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2024 Aug;167(3):538-546.e1.
Epub 2024 Mar 11
doi: 10.1053/j.gastro.2024.03.005.
<span class="bold">PMID: </span><a href="/pubmed/38467383" target="_blank">38467383</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37452811">AGA Clinical Practice Update on Evaluation and Management of Belching, Abdominal Bloating, and Distention: Expert Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Moshiree B,
Drossman D,
Shaukat A</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2023 Sep;165(3):791-800.e3.
Epub 2023 Jul 13
doi: 10.1053/j.gastro.2023.04.039.
<span class="bold">PMID: </span><a href="/pubmed/37452811" target="_blank">37452811</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30391939">Lower Urinary Tract Function in Familial Spastic Paraplegia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sakakibara R,
Shimizu A,
Takahashi O,
Tateno F,
Kishi M,
Aiba Y,
Suzuki H,
Yamamoto T,
Shibata C,
Yamanishi T</span><br />
<span class="medgenPMjournal">Eur Neurol</span>
2018;80(3-4):121-125.
Epub 2018 Nov 2
doi: 10.1159/000494030.
<span class="bold">PMID: </span><a href="/pubmed/30391939" target="_blank">30391939</a></div>
<div class="nl"><a target="_blank" href="/pubmed/17336775">Symptomatic myoclonus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Borg M</span><br />
<span class="medgenPMjournal">Neurophysiol Clin</span>
2006 Sep-Dec;36(5-6):309-18.
Epub 2007 Jan 17
doi: 10.1016/j.neucli.2006.12.006.
<span class="bold">PMID: </span><a href="/pubmed/17336775" target="_blank">17336775</a></div>
<div class="nl"><a target="_blank" href="/pubmed/1970915">Female urinary retention.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wheeler JS Jr,
Culkin DJ,
Walter JS,
Flanigan RC</span><br />
<span class="medgenPMjournal">Urology</span>
1990 May;35(5):428-32.
doi: 10.1016/0090-4295(90)80086-3.
<span class="bold">PMID: </span><a href="/pubmed/1970915" target="_blank">1970915</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dyssynergia%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (284)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/32197987">Use of Botulinum Toxin A (BoNT-A) in Detrusor External Sphincter Dyssynergia (DESD): A Systematic Review and Meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Goel S,
Pierce H,
Pain K,
Christos P,
Dmochowski R,
Chughtai B</span><br />
<span class="medgenPMjournal">Urology</span>
2020 Jun;140:7-13.
Epub 2020 Mar 19
doi: 10.1016/j.urology.2020.03.007.
<span class="bold">PMID: </span><a href="/pubmed/32197987" target="_blank">32197987</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28716323">Chronic Urinary Retention in Multiple Sclerosis Patients: Physiology, Systematic Review of Urodynamic Data, and Recommendations for Care.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Stoffel JT</span><br />
<span class="medgenPMjournal">Urol Clin North Am</span>
2017 Aug;44(3):429-439.
doi: 10.1016/j.ucl.2017.04.009.
<span class="bold">PMID: </span><a href="/pubmed/28716323" target="_blank">28716323</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27214096">Biomarkers to distinguish functional constipation from irritable bowel syndrome with constipation.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Whitehead WE,
Palsson OS,
Simrén M</span><br />
<span class="medgenPMjournal">Neurogastroenterol Motil</span>
2016 Jun;28(6):783-92.
doi: 10.1111/nmo.12852.
<span class="bold">PMID: </span><a href="/pubmed/27214096" target="_blank">27214096</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25800696">Iatrogenic urological triggers of autonomic dysreflexia: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Liu N,
Zhou M,
Biering-Sørensen F,
Krassioukov AV</span><br />
<span class="medgenPMjournal">Spinal Cord</span>
2015 Jul;53(7):500-9.
Epub 2015 Mar 24
doi: 10.1038/sc.2015.39.
<span class="bold">PMID: </span><a href="/pubmed/25800696" target="_blank">25800696</a></div>
<div class="nl"><a target="_blank" href="/pubmed/11686993">Sphincterotomy for biliary sphincter of Oddi dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Craig AG,
Toouli J</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2001;(3):CD001509.
doi: 10.1002/14651858.CD001509.
<span class="bold">PMID: </span><a href="/pubmed/11686993" target="_blank">11686993</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dyssynergia%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0004134%5bDISCUI%5d&amp;filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (74)</a></li>
<li><a href="/gtr/tests?term=C0004134%5bDISCUI%5d&amp;filter=method%3A2%5F18" target="_blank">Mutation scanning of select exons (2)</a></li>
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<li><a href="/gtr/tests?term=C0004134%5bDISCUI%5d&amp;filter=method%3A2%5F19" target="_blank">Targeted variant analysis (1)</a></li>
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