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1113 lines
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<div><div class="rprt full-rprt"><div class="portlet" style="border-top-style: none; margin-top: 0px; padding-top: 0px; margin-bottom: 0px; padding-left: 0.2em;">
|
||
<!--
|
||
UID=9030
|
||
ConceptID=C0017638
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Glioma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>9030</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0017638</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Glial Cell Tumor; Glial Cell Tumors; Gliomas; Tumor, Glial Cell; Tumors, Glial Cell</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Glioma (393564001); Glioma (115240006)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help" data-jig="ncbipopper" href="#target-gene-related">Related genes:<img src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div id="target-gene-related" class="display-none">
|
||
Gene(s) associated with related conditions. For conditions<br />
|
||
in a hierarchy, the parent condition will list the genes<br />
|
||
associated with the children conditions.</div></td>
|
||
<td><a target="_blank" href="/gene/51684">SUFU</a>, <a target="_blank" href="/gene/23432">GPR161</a>, <a target="_blank" href="/gene/8643">PTCH2</a>, <a target="_blank" href="/gene/8518">ELP1</a>, <a target="_blank" href="/gene/7157">TP53</a>, <a target="_blank" href="/gene/3417">IDH1</a>, <a target="_blank" href="/gene/2064">ERBB2</a>, <a target="_blank" href="/gene/1499">CTNNB1</a>, <a target="_blank" href="/gene/675">BRCA2</a></td></tr><tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0009733">HP:0009733</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0021042" target="_blank">MONDO:0021042</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=182067">ORPHA182067</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">The presence of a glioma, which is a neoplasm of the central nervous system originating from a glial cell (astrocytes or oligodendrocytes). [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0017638[DISCUI]&test_type=Clinical" ref="ncbi_uid=9030">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=9030" ref="ncbi_uid=9030">V</a></span></span><span class="TLline">Glioma</span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0004114[DISCUI]&test_type=Clinical" ref="ncbi_uid=438">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=438" target="_blank" href="/omim/137800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=438" ref="ncbi_uid=438">V</a></span></span><span class="TLline"><a href="/medgen/438" ref="tree=GTR&ncbi_uid=438&link_uid=438" title="View MedGen record for 'Astrocytoma'">Astrocytoma</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0017636[DISCUI]&test_type=Clinical" ref="ncbi_uid=42228">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C0017636[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=42228">R</a></span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=42228" ref="ncbi_uid=42228">V</a></span></span><span class="TLline"><a href="/medgen/42228" ref="tree=GTR&ncbi_uid=42228&link_uid=42228" title="View MedGen record for 'Glioblastoma'">Glioblastoma</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0014474[DISCUI]&test_type=Clinical" ref="ncbi_uid=41825">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=41825" target="_blank" href="/omim/137800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=41825" ref="ncbi_uid=41825">V</a></span></span><span class="TLline"><a href="/medgen/41825" ref="tree=GTR&ncbi_uid=41825&link_uid=41825" title="View MedGen record for 'Ependymoma'">Ependymoma</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=64637" target="_blank" href="/omim/137800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/64637" ref="tree=GTR&ncbi_uid=64637&link_uid=64637" title="View MedGen record for 'Subependymal glioma'">Subependymal glioma</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=CN305335[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=986435">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/986435" ref="tree=GTR&ncbi_uid=986435&link_uid=986435" title="View MedGen record for 'Glioma susceptibility'">Glioma susceptibility</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C2750850[DISCUI]&test_type=Clinical" ref="ncbi_uid=413414">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=413414" target="_blank" href="/omim/137800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=413414" ref="ncbi_uid=413414">V</a></span></span><span class="TLline"><a href="/medgen/413414" ref="tree=GTR&ncbi_uid=413414&link_uid=413414" title="View MedGen record for 'Glioma susceptibility 1'">Glioma susceptibility 1</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0025149[DISCUI]&test_type=Clinical" ref="ncbi_uid=7517">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=7517" target="_blank" href="/omim/155255">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=7517" ref="ncbi_uid=7517">V</a></span></span><span class="TLline"><a href="/medgen/7517" ref="tree=GTR&ncbi_uid=7517&link_uid=7517" title="View MedGen record for 'Medulloblastoma'">Medulloblastoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0547065[DISCUI]&test_type=Clinical" ref="ncbi_uid=154285">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/154285" ref="tree=GTR&ncbi_uid=154285&link_uid=154285" title="View MedGen record for 'Oligoastrocytoma'">Oligoastrocytoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0028945[DISCUI]&test_type=Clinical" ref="ncbi_uid=45190">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=45190" target="_blank" href="/omim/137800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=45190" ref="ncbi_uid=45190">V</a></span></span><span class="TLline"><a href="/medgen/45190" ref="tree=GTR&ncbi_uid=45190&link_uid=45190" title="View MedGen record for 'Oligodendroglioma'">Oligodendroglioma</a></span></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/14297" ref="tree=MeSH" title="MedGen record for Malignant neoplastic disease">Malignant neoplastic disease</a></span><ul><li><span class="TLline"><a href="/medgen/99231" ref="tree=MeSH" title="MedGen record for Malignant neoplasm of nervous system">Malignant neoplasm of nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/87593" ref="tree=MeSH" title="MedGen record for Malignant neoplasm of the central nervous system">Malignant neoplasm of the central nervous system</a></span><ul><li><span class="matched_ds">Glioma</span><ul><li><span class="TLline"><a href="/medgen/90811" ref="tree=MeSH" title="MedGen record for Astroblastoma">Astroblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/417678" ref="tree=MeSH" title="MedGen record for Anaplastic Astroblastoma, MN1-Altered">Anaplastic Astroblastoma, MN1-Altered</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/438" ref="tree=MeSH" title="MedGen record for Astrocytoma">Astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/272290" ref="tree=MeSH" title="MedGen record for Adult astrocytic tumor">Adult astrocytic tumor</a></span><ul><li><span class="TLline"><a href="/medgen/233962" ref="tree=MeSH" title="MedGen record for Adult brainstem astrocytoma">Adult brainstem astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/79278" ref="tree=MeSH" title="MedGen record for Adult infiltrating astrocytic neoplasm">Adult infiltrating astrocytic neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/128889" ref="tree=MeSH" title="MedGen record for Adult Pilocytic Astrocytoma">Adult Pilocytic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/859690" ref="tree=MeSH" title="MedGen record for Adult Pineal Gland Astrocytoma">Adult Pineal Gland Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/321874" ref="tree=MeSH" title="MedGen record for Adult Subependymal Giant Cell Astrocytoma">Adult Subependymal Giant Cell Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/924393" ref="tree=MeSH" title="MedGen record for Anaplastic pleomorphic xanthoastrocytoma">Anaplastic pleomorphic xanthoastrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/1685266" ref="tree=MeSH" title="MedGen record for Recurrent Anaplastic Pleomorphic Xanthoastrocytoma">Recurrent Anaplastic Pleomorphic Xanthoastrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1701639" ref="tree=MeSH" title="MedGen record for Refractory Anaplastic Pleomorphic Xanthoastrocytoma">Refractory Anaplastic Pleomorphic Xanthoastrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/137784" ref="tree=MeSH" title="MedGen record for Astrocytoma, anaplastic">Astrocytoma, anaplastic</a></span><ul><li><span class="TLline"><a href="/medgen/76118" ref="tree=MeSH" title="MedGen record for Adult Anaplastic Astrocytoma">Adult Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/927512" ref="tree=MeSH" title="MedGen record for Anaplastic Astrocytoma, IDH-Wildtype">Anaplastic Astrocytoma, IDH-Wildtype</a></span></li><li><span class="TLline"><a href="/medgen/233983" ref="tree=MeSH" title="MedGen record for Anaplastic Brain Stem Astrocytoma">Anaplastic Brain Stem Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/231068" ref="tree=MeSH" title="MedGen record for Anaplastic Diencephalic Astrocytoma">Anaplastic Diencephalic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/927513" ref="tree=MeSH" title="MedGen record for Astrocytoma, IDH-mutant, grade 3">Astrocytoma, IDH-mutant, grade 3</a></span></li><li><span class="TLline"><a href="/medgen/1635918" ref="tree=MeSH" title="MedGen record for Childhood Anaplastic Astrocytoma">Childhood Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/231069" ref="tree=MeSH" title="MedGen record for Hemispheric Anaplastic Astrocytoma">Hemispheric Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1621925" ref="tree=MeSH" title="MedGen record for Recurrent Anaplastic Astrocytoma">Recurrent Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1709594" ref="tree=MeSH" title="MedGen record for Refractory Anaplastic Astrocytoma">Refractory Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/231374" ref="tree=MeSH" title="MedGen record for Secondary Supratentorial Anaplastic Astrocytoma">Secondary Supratentorial Anaplastic Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/811330" ref="tree=MeSH" title="MedGen record for Brain astrocytoma">Brain astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/231458" ref="tree=MeSH" title="MedGen record for Brain stem astrocytic neoplasm">Brain stem astrocytic neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/196631" ref="tree=MeSH" title="MedGen record for Cerebellar astrocytoma">Cerebellar astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/196691" ref="tree=MeSH" title="MedGen record for Cerebral astrocytoma">Cerebral astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/234121" ref="tree=MeSH" title="MedGen record for Childhood Brain Anaplastic Astrocytoma">Childhood Brain Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/232072" ref="tree=MeSH" title="MedGen record for Childhood optic tract astrocytoma">Childhood optic tract astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/272542" ref="tree=MeSH" title="MedGen record for Diencephalic astrocytomas">Diencephalic astrocytomas</a></span></li><li><span class="TLline"><a href="/medgen/83711" ref="tree=MeSH" title="MedGen record for Pineal gland astrocytoma">Pineal gland astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1660183" ref="tree=MeSH" title="MedGen record for Supratentorial Pleomorphic Xanthoastrocytoma">Supratentorial Pleomorphic Xanthoastrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1663242" ref="tree=MeSH" title="MedGen record for Third Ventricle Pilocytic Astrocytoma">Third Ventricle Pilocytic Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/235225" ref="tree=MeSH" title="MedGen record for Cauda equina intradural extramedullary astrocytoma">Cauda equina intradural extramedullary astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/272112" ref="tree=MeSH" title="MedGen record for Childhood astrocytic tumor">Childhood astrocytic tumor</a></span><ul><li><span class="TLline"><a href="/medgen/898003" ref="tree=MeSH" title="MedGen record for Childhood Astrocytoma">Childhood Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/128836" ref="tree=MeSH" title="MedGen record for Childhood Glioblastoma">Childhood Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/857352" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Astrocytic Tumor">Recurrent Childhood Astrocytic Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/42228" ref="tree=MeSH" title="MedGen record for Glioblastoma">Glioblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/83169" ref="tree=MeSH" title="MedGen record for Giant cell glioblastoma">Giant cell glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/64638" ref="tree=MeSH" title="MedGen record for Gliosarcoma">Gliosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/226850" ref="tree=MeSH" title="MedGen record for Gliofibroma">Gliofibroma</a></span></li><li><span class="TLline"><a href="/medgen/457397" ref="tree=MeSH" title="MedGen record for Glioneuronal Tumor with Neuropil-Like Islands">Glioneuronal Tumor with Neuropil-Like Islands</a></span></li><li><span class="TLline"><a href="/medgen/769639" ref="tree=MeSH" title="MedGen record for High grade astrocytic tumor">High grade astrocytic tumor</a></span><ul><li><span class="TLline"><a href="/medgen/458884" ref="tree=MeSH" title="MedGen record for Diffuse intrinsic pontine glioma">Diffuse intrinsic pontine glioma</a></span></li><li><span class="TLline"><a href="/medgen/301585" ref="tree=MeSH" title="MedGen record for Glioblastoma multiforme">Glioblastoma multiforme</a></span></li><li><span class="TLline"><a href="/medgen/87267" ref="tree=MeSH" title="MedGen record for Gliomatosis cerebri">Gliomatosis cerebri</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/727259" ref="tree=MeSH" title="MedGen record for Low-grade astrocytoma">Low-grade astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/83708" ref="tree=MeSH" title="MedGen record for Diffuse astrocytoma">Diffuse astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1791573" ref="tree=MeSH" title="MedGen record for Metastatic Low Grade Astrocytoma">Metastatic Low Grade Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/87271" ref="tree=MeSH" title="MedGen record for Pilocytic astrocytoma">Pilocytic astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/458776" ref="tree=MeSH" title="MedGen record for Pituicytoma">Pituicytoma</a></span></li><li><span class="TLline"><a href="/medgen/137786" ref="tree=MeSH" title="MedGen record for Pleomorphic xanthoastrocytoma">Pleomorphic xanthoastrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1781955" ref="tree=MeSH" title="MedGen record for Recurrent Low Grade Astrocytoma">Recurrent Low Grade Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1791071" ref="tree=MeSH" title="MedGen record for Refractory Low Grade Astrocytoma">Refractory Low Grade Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/61446" ref="tree=MeSH" title="MedGen record for Subependymal giant-cell astrocytoma">Subependymal giant-cell astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/237052" ref="tree=MeSH" title="MedGen record for Optic tract astrocytoma">Optic tract astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/235405" ref="tree=MeSH" title="MedGen record for Optic nerve astrocytoma">Optic nerve astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/137924" ref="tree=MeSH" title="MedGen record for Retinal astrocytic hamartoma">Retinal astrocytic hamartoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/276757" ref="tree=MeSH" title="MedGen record for Pilomyxoid astrocytoma">Pilomyxoid astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/859240" ref="tree=MeSH" title="MedGen record for Childhood Pilomyxoid Astrocytoma">Childhood Pilomyxoid Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1663605" ref="tree=MeSH" title="MedGen record for Hypothalamic-Chiasmatic Pilomyxoid Astrocytoma">Hypothalamic-Chiasmatic Pilomyxoid Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/91152" ref="tree=MeSH" title="MedGen record for Spinal cord astrocytoma">Spinal cord astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1764584" ref="tree=MeSH" title="MedGen record for Bilateral Thalamic Glioma">Bilateral Thalamic Glioma</a></span></li><li><span class="TLline"><a href="/medgen/195650" ref="tree=MeSH" title="MedGen record for Brainstem glioma">Brainstem glioma</a></span><ul><li><span class="TLline"><a href="/medgen/124526" ref="tree=MeSH" title="MedGen record for Adult brainstem glioma">Adult brainstem glioma</a></span><ul><li><span class="TLline"><a href="/medgen/277992" ref="tree=MeSH" title="MedGen record for Adult brainstem gliosarcoma">Adult brainstem gliosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/237180" ref="tree=MeSH" title="MedGen record for Adult brainstem mixed glioma">Adult brainstem mixed glioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/231067" ref="tree=MeSH" title="MedGen record for Anaplastic Brain Stem Glioma">Anaplastic Brain Stem Glioma</a></span></li><li><span class="TLline"><a href="/medgen/231459" ref="tree=MeSH" title="MedGen record for Brain stem ependymoma">Brain stem ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/231460" ref="tree=MeSH" title="MedGen record for Brain Stem Glioblastoma">Brain Stem Glioblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/854376" ref="tree=MeSH" title="MedGen record for Childhood Brain Stem Gliosarcoma">Childhood Brain Stem Gliosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124481" ref="tree=MeSH" title="MedGen record for Childhood brain stem glioma">Childhood brain stem glioma</a></span><ul><li><span class="TLline"><a href="/medgen/854375" ref="tree=MeSH" title="MedGen record for Childhood Brain Stem Mixed Glioma">Childhood Brain Stem Mixed Glioma</a></span></li><li><span class="TLline"><a href="/medgen/234123" ref="tree=MeSH" title="MedGen record for Childhood brainstem astrocytoma">Childhood brainstem astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/90909" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Brain Stem Glioma">Recurrent Childhood Brain Stem Glioma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/869274" ref="tree=MeSH" title="MedGen record for Cerebellar glioma">Cerebellar glioma</a></span></li><li><span class="TLline"><a href="/medgen/232956" ref="tree=MeSH" title="MedGen record for Chordoid glioma of the third ventricle">Chordoid glioma of the third ventricle</a></span></li><li><span class="TLline"><a href="/medgen/927222" ref="tree=MeSH" title="MedGen record for Diffuse Glioma">Diffuse Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/90812" ref="tree=MeSH" title="MedGen record for Anaplastic oligodendroglioma">Anaplastic oligodendroglioma</a></span><ul><li><span class="TLline"><a href="/medgen/128892" ref="tree=MeSH" title="MedGen record for Adult Anaplastic Oligodendroglioma">Adult Anaplastic Oligodendroglioma</a></span></li><li><span class="TLline"><a href="/medgen/927511" ref="tree=MeSH" title="MedGen record for Anaplastic Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted">Anaplastic Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted</a></span></li><li><span class="TLline"><a href="/medgen/272457" ref="tree=MeSH" title="MedGen record for Childhood Anaplastic Oligodendroglioma">Childhood Anaplastic Oligodendroglioma</a></span></li><li><span class="TLline"><a href="/medgen/1650540" ref="tree=MeSH" title="MedGen record for Frontal Lobe Anaplastic Oligodendroglioma">Frontal Lobe Anaplastic Oligodendroglioma</a></span></li><li><span class="TLline"><a href="/medgen/1631096" ref="tree=MeSH" title="MedGen record for Recurrent Anaplastic Oligodendroglioma">Recurrent Anaplastic Oligodendroglioma</a></span></li><li><span class="TLline"><a href="/medgen/1716709" ref="tree=MeSH" title="MedGen record for Refractory Anaplastic Oligodendroglioma">Refractory Anaplastic Oligodendroglioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/927220" ref="tree=MeSH" title="MedGen record for Diffuse midline glioma, H3 K27M-mutant">Diffuse midline glioma, H3 K27M-mutant</a></span><ul><li><span class="TLline"><a href="/medgen/1791979" ref="tree=MeSH" title="MedGen record for Recurrent Diffuse Midline Glioma, H3 K27M-Mutant">Recurrent Diffuse Midline Glioma, H3 K27M-Mutant</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/75477" ref="tree=MeSH" title="MedGen record for Mixed glioma">Mixed glioma</a></span><ul><li><span class="TLline"><a href="/medgen/859693" ref="tree=MeSH" title="MedGen record for Adult Mixed Glioma">Adult Mixed Glioma</a></span></li><li><span class="TLline"><a href="/medgen/96556" ref="tree=MeSH" title="MedGen record for Anaplastic oligoastrocytoma">Anaplastic oligoastrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/859246" ref="tree=MeSH" title="MedGen record for Childhood Mixed Glioma">Childhood Mixed Glioma</a></span></li><li><span class="TLline"><a href="/medgen/76166" ref="tree=MeSH" title="MedGen record for Mixed astrocytoma-ependymoma">Mixed astrocytoma-ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/79184" ref="tree=MeSH" title="MedGen record for Mixed astrocytoma-ependymoma-oligodendroglioma">Mixed astrocytoma-ependymoma-oligodendroglioma</a></span></li><li><span class="TLline"><a href="/medgen/79185" ref="tree=MeSH" title="MedGen record for Oligoastrocytic tumor">Oligoastrocytic tumor</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/232459" ref="tree=MeSH" title="MedGen record for Ependymal tumor">Ependymal tumor</a></span><ul><li><span class="TLline"><a href="/medgen/323813" ref="tree=MeSH" title="MedGen record for Adult Ependymal Tumor">Adult Ependymal Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/83709" ref="tree=MeSH" title="MedGen record for Adult anaplastic ependymoma">Adult anaplastic ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/78896" ref="tree=MeSH" title="MedGen record for Adult Ependymoma">Adult Ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/854377" ref="tree=MeSH" title="MedGen record for Adult Myxopapillary Ependymoma">Adult Myxopapillary Ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/79277" ref="tree=MeSH" title="MedGen record for Adult Subependymoma">Adult Subependymoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/128891" ref="tree=MeSH" title="MedGen record for Anaplastic ependymoma">Anaplastic ependymoma</a></span><ul><li><span class="TLline"><a href="/medgen/906224" ref="tree=MeSH" title="MedGen record for Childhood Anaplastic Ependymoma">Childhood Anaplastic Ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/1693176" ref="tree=MeSH" title="MedGen record for Recurrent Anaplastic Ependymoma">Recurrent Anaplastic Ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/1703773" ref="tree=MeSH" title="MedGen record for Refractory Anaplastic Ependymoma">Refractory Anaplastic Ependymoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/859261" ref="tree=MeSH" title="MedGen record for Childhood Ependymal Tumor">Childhood Ependymal Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/343609" ref="tree=MeSH" title="MedGen record for Childhood ependymoma">Childhood ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/908952" ref="tree=MeSH" title="MedGen record for Childhood Myxopapillary Ependymoma">Childhood Myxopapillary Ependymoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/116038" ref="tree=MeSH" title="MedGen record for Ependymal tumor of brain">Ependymal tumor of brain</a></span><ul><li><span class="TLline"><a href="/medgen/1670388" ref="tree=MeSH" title="MedGen record for Brain Ependymoma">Brain Ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/1393571" ref="tree=MeSH" title="MedGen record for Cerebellar and Brain Stem Ependymal Tumor">Cerebellar and Brain Stem Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1389242" ref="tree=MeSH" title="MedGen record for Cerebellar and Ventricular Ependymal Tumor">Cerebellar and Ventricular Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1383048" ref="tree=MeSH" title="MedGen record for Cerebellar, Fourth Ventricle, and Brain Stem Ependymal Tumor">Cerebellar, Fourth Ventricle, and Brain Stem Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1378217" ref="tree=MeSH" title="MedGen record for Frontal Lobe and Parietal Lobe Ependymal Tumor">Frontal Lobe and Parietal Lobe Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1385705" ref="tree=MeSH" title="MedGen record for Infratentorial ependymal tumor">Infratentorial ependymal tumor</a></span></li><li><span class="TLline"><a href="/medgen/1371874" ref="tree=MeSH" title="MedGen record for Occipital Lobe, Parietal Lobe, and Ventricular Ependymal Tumor">Occipital Lobe, Parietal Lobe, and Ventricular Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1372579" ref="tree=MeSH" title="MedGen record for Parietal Lobe and Occipital Lobe Ependymal Tumor">Parietal Lobe and Occipital Lobe Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1389924" ref="tree=MeSH" title="MedGen record for Posterior Fossa Ependymal Tumor">Posterior Fossa Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1379596" ref="tree=MeSH" title="MedGen record for Supratentorial ependymal tumor">Supratentorial ependymal tumor</a></span></li><li><span class="TLline"><a href="/medgen/1374204" ref="tree=MeSH" title="MedGen record for Temporal Lobe and Parietal Lobe Ependymal Tumor">Temporal Lobe and Parietal Lobe Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1385359" ref="tree=MeSH" title="MedGen record for Temporal Lobe, Parietal Lobe, and Lateral Ventricle Ependymal Tumor">Temporal Lobe, Parietal Lobe, and Lateral Ventricle Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1388921" ref="tree=MeSH" title="MedGen record for Ventricular and Brain Stem Ependymal Tumor">Ventricular and Brain Stem Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1378899" ref="tree=MeSH" title="MedGen record for Ventricular Ependymal Tumor">Ventricular Ependymal Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1379203" ref="tree=MeSH" title="MedGen record for Ependymal Tumor of Brain and Spinal Cord">Ependymal Tumor of Brain and Spinal Cord</a></span><ul><li><span class="TLline"><a href="/medgen/1382563" ref="tree=MeSH" title="MedGen record for Cerebellar, Brain Stem, and Cervical Spinal Cord Ependymal Tumor">Cerebellar, Brain Stem, and Cervical Spinal Cord Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1372129" ref="tree=MeSH" title="MedGen record for Infratentorial and Spinal Cord Ependymal Tumor">Infratentorial and Spinal Cord Ependymal Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1389203" ref="tree=MeSH" title="MedGen record for Ependymal tumor of spinal cord">Ependymal tumor of spinal cord</a></span><ul><li><span class="TLline"><a href="/medgen/1381580" ref="tree=MeSH" title="MedGen record for Cervical and Lumbosacral Spinal Cord Ependymal Tumor">Cervical and Lumbosacral Spinal Cord Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1391795" ref="tree=MeSH" title="MedGen record for Cervical and Thoracic Spinal Cord Ependymal Tumor">Cervical and Thoracic Spinal Cord Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1375805" ref="tree=MeSH" title="MedGen record for Cervical Spinal Cord Ependymal Tumor">Cervical Spinal Cord Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1373588" ref="tree=MeSH" title="MedGen record for Cervical, Thoracic, and Lumbosacral Spinal Cord Ependymal Tumor">Cervical, Thoracic, and Lumbosacral Spinal Cord Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1379499" ref="tree=MeSH" title="MedGen record for Lumbosacral Spinal Cord Ependymal Tumor">Lumbosacral Spinal Cord Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/65968" ref="tree=MeSH" title="MedGen record for Spinal cord ependymoma">Spinal cord ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/1372829" ref="tree=MeSH" title="MedGen record for Thoracic and Lumbosacral Spinal Cord Ependymal Tumor">Thoracic and Lumbosacral Spinal Cord Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1383650" ref="tree=MeSH" title="MedGen record for Thoracic Spinal Cord Ependymal Tumor">Thoracic Spinal Cord Ependymal Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/41825" ref="tree=MeSH" title="MedGen record for Ependymoma">Ependymoma</a></span><ul><li><span class="TLline"><a href="/medgen/235137" ref="tree=MeSH" title="MedGen record for Cellular ependymoma">Cellular ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/90810" ref="tree=MeSH" title="MedGen record for Papillary ependymoma">Papillary ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/1679281" ref="tree=MeSH" title="MedGen record for Recurrent Ependymoma">Recurrent Ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/1637579" ref="tree=MeSH" title="MedGen record for Refractory Ependymoma">Refractory Ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/64637" ref="tree=MeSH" title="MedGen record for Subependymal glioma">Subependymal glioma</a></span></li><li><span class="TLline"><a href="/medgen/237159" ref="tree=MeSH" title="MedGen record for Tanycytic ependymoma">Tanycytic ependymoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/104717" ref="tree=MeSH" title="MedGen record for Myxopapillary ependymoma">Myxopapillary ependymoma</a></span></li><li><span class="TLline"><a href="/medgen/1389857" ref="tree=MeSH" title="MedGen record for Recurrent Ependymal Tumor">Recurrent Ependymal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/927113" ref="tree=MeSH" title="MedGen record for RELA fusion-positive ependymoma">RELA fusion-positive ependymoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/60216" ref="tree=MeSH" title="MedGen record for Ganglioglioma">Ganglioglioma</a></span><ul><li><span class="TLline"><a href="/medgen/231040" ref="tree=MeSH" title="MedGen record for Adult Ganglioglioma">Adult Ganglioglioma</a></span></li><li><span class="TLline"><a href="/medgen/234128" ref="tree=MeSH" title="MedGen record for Childhood ganglioglioma">Childhood ganglioglioma</a></span></li><li><span class="TLline"><a href="/medgen/1786513" ref="tree=MeSH" title="MedGen record for Nasal ganglioglioma">Nasal ganglioglioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/986435" ref="tree=MeSH" title="MedGen record for Glioma susceptibility">Glioma susceptibility</a></span></li><li><span class="TLline"><a href="/medgen/413414" ref="tree=MeSH" title="MedGen record for Glioma susceptibility 1">Glioma susceptibility 1</a></span></li><li><span class="TLline"><a href="/medgen/744283" ref="tree=MeSH" title="MedGen record for Low grade glioma">Low grade glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1391502" ref="tree=MeSH" title="MedGen record for Grade II glioma">Grade II glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1632231" ref="tree=MeSH" title="MedGen record for Recurrent WHO Grade 2 Glioma">Recurrent WHO Grade 2 Glioma</a></span></li><li><span class="TLline"><a href="/medgen/1682187" ref="tree=MeSH" title="MedGen record for Refractory WHO Grade 2 Glioma">Refractory WHO Grade 2 Glioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1791572" ref="tree=MeSH" title="MedGen record for Metastatic Low Grade Glioma">Metastatic Low Grade Glioma</a></span></li><li><span class="TLline"><a href="/medgen/1791070" ref="tree=MeSH" title="MedGen record for Recurrent Low Grade Glioma">Recurrent Low Grade Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1791072" ref="tree=MeSH" title="MedGen record for Recurrent WHO Grade 1 Glioma">Recurrent WHO Grade 1 Glioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1791069" ref="tree=MeSH" title="MedGen record for Refractory Low Grade Glioma">Refractory Low Grade Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1791074" ref="tree=MeSH" title="MedGen record for Refractory WHO Grade 1 Glioma">Refractory WHO Grade 1 Glioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1656726" ref="tree=MeSH" title="MedGen record for Unresectable Low Grade Glioma">Unresectable Low Grade Glioma</a></span></li><li><span class="TLline"><a href="/medgen/1791073" ref="tree=MeSH" title="MedGen record for WHO Grade 1 Glioma">WHO Grade 1 Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/453267" ref="tree=MeSH" title="MedGen record for Angiocentric glioma">Angiocentric glioma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/107826" ref="tree=MeSH" title="MedGen record for Malignant glioma">Malignant glioma</a></span><ul><li><span class="TLline"><a href="/medgen/925529" ref="tree=MeSH" title="MedGen record for Grade III glioma">Grade III glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1641844" ref="tree=MeSH" title="MedGen record for Recurrent WHO Grade 3 Glioma">Recurrent WHO Grade 3 Glioma</a></span></li><li><span class="TLline"><a href="/medgen/1659708" ref="tree=MeSH" title="MedGen record for Refractory WHO Grade 3 Glioma">Refractory WHO Grade 3 Glioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/578810" ref="tree=MeSH" title="MedGen record for Malignant Brain Glioma">Malignant Brain Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/138100" ref="tree=MeSH" title="MedGen record for Brain glioblastoma">Brain glioblastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233693" ref="tree=MeSH" title="MedGen record for Meningeal Gliomatosis">Meningeal Gliomatosis</a></span></li><li><span class="TLline"><a href="/medgen/1789444" ref="tree=MeSH" title="MedGen record for Metastatic Glioma">Metastatic Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1793124" ref="tree=MeSH" title="MedGen record for Locally Advanced Glioma">Locally Advanced Glioma</a></span></li><li><span class="TLline"><a href="/medgen/1762790" ref="tree=MeSH" title="MedGen record for Metastatic Glioblastoma">Metastatic Glioblastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1646561" ref="tree=MeSH" title="MedGen record for Recurrent Malignant Glioma">Recurrent Malignant Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1624822" ref="tree=MeSH" title="MedGen record for Recurrent Diffuse Intrinsic Pontine Glioma">Recurrent Diffuse Intrinsic Pontine Glioma</a></span></li><li><span class="TLline"><a href="/medgen/925837" ref="tree=MeSH" title="MedGen record for Recurrent Glioblastoma">Recurrent Glioblastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1635459" ref="tree=MeSH" title="MedGen record for Refractory Malignant Glioma">Refractory Malignant Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1627149" ref="tree=MeSH" title="MedGen record for Refractory Diffuse Intrinsic Pontine Glioma">Refractory Diffuse Intrinsic Pontine Glioma</a></span></li><li><span class="TLline"><a href="/medgen/1645398" ref="tree=MeSH" title="MedGen record for Refractory Glioblastoma">Refractory Glioblastoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/7517" ref="tree=MeSH" title="MedGen record for Medulloblastoma">Medulloblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/78898" ref="tree=MeSH" title="MedGen record for Adult medulloblastoma">Adult medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/457446" ref="tree=MeSH" title="MedGen record for Anaplastic Medulloblastoma">Anaplastic Medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1389864" ref="tree=MeSH" title="MedGen record for Anaplastic/large cell medulloblastoma">Anaplastic/large cell medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/870487" ref="tree=MeSH" title="MedGen record for Cerebellar medulloblastoma">Cerebellar medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/232044" ref="tree=MeSH" title="MedGen record for Cerebellar vermis medulloblastoma">Cerebellar vermis medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/75829" ref="tree=MeSH" title="MedGen record for Childhood medulloblastoma">Childhood medulloblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/137886" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Medulloblastoma">Recurrent Childhood Medulloblastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/353541" ref="tree=MeSH" title="MedGen record for Classic medulloblastoma">Classic medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/148272" ref="tree=MeSH" title="MedGen record for Desmoplastic/nodular medulloblastoma">Desmoplastic/nodular medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/234263" ref="tree=MeSH" title="MedGen record for Familial Adenomatous Polyposis Associated Medulloblastoma">Familial Adenomatous Polyposis Associated Medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1653585" ref="tree=MeSH" title="MedGen record for Fourth Ventricle Medulloblastoma">Fourth Ventricle Medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/226852" ref="tree=MeSH" title="MedGen record for Large cell medulloblastoma">Large cell medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/233759" ref="tree=MeSH" title="MedGen record for Medulloblastoma with extensive nodularity">Medulloblastoma with extensive nodularity</a></span></li><li><span class="TLline"><a href="/medgen/1371227" ref="tree=MeSH" title="MedGen record for Medulloblastoma, Not Otherwise Specified">Medulloblastoma, Not Otherwise Specified</a></span></li><li><span class="TLline"><a href="/medgen/104731" ref="tree=MeSH" title="MedGen record for Medullomyoblastoma with myogenic differentiation">Medullomyoblastoma with myogenic differentiation</a></span></li><li><span class="TLline"><a href="/medgen/224818" ref="tree=MeSH" title="MedGen record for Melanotic medulloblastoma">Melanotic medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1783727" ref="tree=MeSH" title="MedGen record for Metastatic Medulloblastoma">Metastatic Medulloblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/277356" ref="tree=MeSH" title="MedGen record for Medulloblastoma with Leptomeningeal Spread">Medulloblastoma with Leptomeningeal Spread</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/277414" ref="tree=MeSH" title="MedGen record for Nevoid Basal Cell Carcinoma Syndrome Associated Medulloblastoma">Nevoid Basal Cell Carcinoma Syndrome Associated Medulloblastoma</a></span></li><li><span class="TLline"><a href="/medgen/235539" ref="tree=MeSH" title="MedGen record for Recurrent Medulloblastoma">Recurrent Medulloblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/1633055" ref="tree=MeSH" title="MedGen record for Recurrent Medulloblastoma, SHH-Activated">Recurrent Medulloblastoma, SHH-Activated</a></span></li><li><span class="TLline"><a href="/medgen/1793138" ref="tree=MeSH" title="MedGen record for Recurrent Medulloblastoma, WNT-Activated">Recurrent Medulloblastoma, WNT-Activated</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1642493" ref="tree=MeSH" title="MedGen record for Refractory Medulloblastoma">Refractory Medulloblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/1642267" ref="tree=MeSH" title="MedGen record for Refractory Medulloblastoma, SHH-Activated">Refractory Medulloblastoma, SHH-Activated</a></span></li><li><span class="TLline"><a href="/medgen/1793137" ref="tree=MeSH" title="MedGen record for Refractory Medulloblastoma, WNT-Activated">Refractory Medulloblastoma, WNT-Activated</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233916" ref="tree=MeSH" title="MedGen record for Region 17p13 Allelic Loss Associated Medulloblastoma">Region 17p13 Allelic Loss Associated Medulloblastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/154285" ref="tree=MeSH" title="MedGen record for Oligoastrocytoma">Oligoastrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/233266" ref="tree=MeSH" title="MedGen record for Oligodendroglial tumor">Oligodendroglial tumor</a></span><ul><li><span class="TLline"><a href="/medgen/289306" ref="tree=MeSH" title="MedGen record for Adult Oligodendroglial Tumor">Adult Oligodendroglial Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/75924" ref="tree=MeSH" title="MedGen record for Adult oligodendroglioma">Adult oligodendroglioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/45190" ref="tree=MeSH" title="MedGen record for Oligodendroglioma">Oligodendroglioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/138056" ref="tree=MeSH" title="MedGen record for Optic nerve glioma">Optic nerve glioma</a></span><ul><li><span class="TLline"><a href="/medgen/234589" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Optic Nerve Glioma">Recurrent Childhood Optic Nerve Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/277579" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Optic Nerve Astrocytoma">Recurrent Childhood Optic Nerve Astrocytoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/162950" ref="tree=MeSH" title="MedGen record for Optic pathway glioma">Optic pathway glioma</a></span><ul><li><span class="TLline"><a href="/medgen/124487" ref="tree=MeSH" title="MedGen record for Childhood optic nerve glioma">Childhood optic nerve glioma</a></span><ul><li><span class="TLline"><a href="/medgen/137884" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Visual Pathway Glioma">Recurrent Childhood Visual Pathway Glioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1661286" ref="tree=MeSH" title="MedGen record for Recurrent Visual Pathway Glioma">Recurrent Visual Pathway Glioma</a></span></li><li><span class="TLline"><a href="/medgen/1667706" ref="tree=MeSH" title="MedGen record for Refractory Visual Pathway Glioma">Refractory Visual Pathway Glioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1391323" ref="tree=MeSH" title="MedGen record for Recurrent Glioma">Recurrent Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1792787" ref="tree=MeSH" title="MedGen record for Recurrent Tectal Glioma">Recurrent Tectal Glioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1633847" ref="tree=MeSH" title="MedGen record for Refractory Glioma">Refractory Glioma</a></span></li><li><span class="TLline"><a href="/medgen/1719148" ref="tree=MeSH" title="MedGen record for Resectable Glioma">Resectable Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1715986" ref="tree=MeSH" title="MedGen record for Resectable Glioblastoma">Resectable Glioblastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/423646" ref="tree=MeSH" title="MedGen record for Spinal cord glioma">Spinal cord glioma</a></span><ul><li><span class="TLline"><a href="/medgen/138055" ref="tree=MeSH" title="MedGen record for Spinal cord oligodendroglioma">Spinal cord oligodendroglioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1792786" ref="tree=MeSH" title="MedGen record for Tectal Glioma">Tectal Glioma</a></span></li><li><span class="TLline"><a href="/medgen/1784331" ref="tree=MeSH" title="MedGen record for Unresectable Glioma">Unresectable Glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1788246" ref="tree=MeSH" title="MedGen record for Unresectable Glioblastoma">Unresectable Glioblastoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=18203&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Glioma</span> in Orphanet.</div></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="divPopper rprt" id="rdis_18013"><div><strong>Neurofibromatosis, type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>18013</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0027831</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
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<div class="spaceAbove">Neurofibromatosis 1 (NF1) is a multisystem disorder characterized by multiple café au lait macules, intertriginous freckling, multiple cutaneous neurofibromas, and learning disability or behavior problems. About half of people with NF1 have plexiform neurofibromas, but most are internal and not suspected clinically. Plexiform neurofibromas can cause pain, neurologic deficits, and abnormalities of involved or adjacent structures. Less common but potentially more serious manifestations include optic nerve and other central nervous system gliomas, malignant peripheral nerve sheath tumors, scoliosis, tibial dysplasia, vasculopathy, and gastrointestinal, endocrine, or pulmonary disease.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/18013">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_137970"><div><strong>Hamartoma of hypothalamus</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>137970</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0342418</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
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<div class="spaceAbove">Pallister-Hall-like syndrome (PHLS) is a pleiotropic autosomal recessive disorder characterized by phenotypic variability. Patients exhibit postaxial polydactyly as well as hypothalamic hamartoma, cardiac and skeletal anomalies, and craniofacial dysmorphisms. Hirschsprung disease has also been observed (Rubino et al., 2018; Le et al., 2020). Pallister-Hall syndrome (146510) is an autosomal dominant disorder with features overlapping those of PHLS, caused by mutation in the GLI3 gene (165240).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/137970">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_140771"><div><strong>Microcephaly, normal intelligence and immunodeficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>140771</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0398791</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Nijmegen breakage syndrome (NBS) is characterized by progressive microcephaly, early growth deficiency that improves with age, recurrent respiratory infections, an increased risk for malignancy (primarily lymphoma), and premature ovarian failure in females. Developmental milestones are attained at the usual time during the first year; however, borderline delays in development and hyperactivity may be observed in early childhood. Intellectual abilities tend to decline over time. Recurrent pneumonia and bronchitis may result in respiratory failure and early death. Other reported malignancies include solid tumors (e.g., medulloblastoma, glioma, rhabdomyosarcoma).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/140771">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1849727"><div><strong>Li-Fraumeni syndrome 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1849727</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882668</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Li-Fraumeni syndrome is a rare disorder that greatly increases the risk of developing several types of cancer, particularly in children and young adults.\n\nThe cancers most often associated with Li-Fraumeni syndrome include breast cancer, a form of bone cancer called osteosarcoma, and cancers of soft tissues (such as muscle) called soft tissue sarcomas. Other cancers commonly seen in this syndrome include brain tumors, cancers of blood-forming tissues (leukemias), and a cancer called adrenocortical carcinoma that affects the outer layer of the adrenal glands (small hormone-producing glands on top of each kidney). Several other types of cancer also occur more frequently in people with Li-Fraumeni syndrome.\n\nA very similar condition called Li-Fraumeni-like syndrome shares many of the features of classic Li-Fraumeni syndrome. Both conditions significantly increase the chances of developing multiple cancers beginning in childhood; however, the pattern of specific cancers seen in affected family members is different.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1849727">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_137970" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hamartoma of hypothalamus</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1849727" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Li-Fraumeni syndrome 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_140771" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Microcephaly, normal intelligence and immunodeficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_18013" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neurofibromatosis, type 1</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37738997">Primary brain tumours in adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">van den Bent MJ,
|
||
Geurts M,
|
||
French PJ,
|
||
Smits M,
|
||
Capper D,
|
||
Bromberg JEC,
|
||
Chang SM</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2023 Oct 28;402(10412):1564-1579.
|
||
Epub 2023 Sep 19
|
||
doi: 10.1016/S0140-6736(23)01054-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37738997" target="_blank">37738997</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32044356">Immunotherapy for glioma: Current management and future application.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Xu S,
|
||
Tang L,
|
||
Li X,
|
||
Fan F,
|
||
Liu Z</span><br />
|
||
<span class="medgenPMjournal">Cancer Lett</span>
|
||
2020 Apr 28;476:1-12.
|
||
Epub 2020 Feb 7
|
||
doi: 10.1016/j.canlet.2020.02.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32044356" target="_blank">32044356</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30531227">Management of pediatric low-grade glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Blank P,
|
||
Bandopadhayay P,
|
||
Haas-Kogan D,
|
||
Fouladi M,
|
||
Fangusaro J</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Pediatr</span>
|
||
2019 Feb;31(1):21-27.
|
||
doi: 10.1097/MOP.0000000000000717.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30531227" target="_blank">30531227</a><a href="/pmc/articles/PMC6664811" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22glioma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (2015)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/22138009">NCCN Task Force report: Evaluating the clinical utility of tumor markers in oncology.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Febbo PG,
|
||
Ladanyi M,
|
||
Aldape KD,
|
||
De Marzo AM,
|
||
Hammond ME,
|
||
Hayes DF,
|
||
Iafrate AJ,
|
||
Kelley RK,
|
||
Marcucci G,
|
||
Ogino S,
|
||
Pao W,
|
||
Sgroi DC,
|
||
Birkeland ML</span><br />
|
||
<span class="medgenPMjournal">J Natl Compr Canc Netw</span>
|
||
2011 Nov;9 Suppl 5:S1-32; quiz S33.
|
||
doi: 10.6004/jnccn.2011.0137.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22138009" target="_blank">22138009</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=" title="PubMed search"></a></div><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/cns.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Central Nervous System Cancers, 2023</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng99" target="_blank">UK NICE Guideline NG99, Brain tumours (primary) and brain metastases in over 16s, 2021</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37832944">Role of the Microenvironment in Glioma Pathogenesis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jayaram MA,
|
||
Phillips JJ</span><br />
|
||
<span class="medgenPMjournal">Annu Rev Pathol</span>
|
||
2024 Jan 24;19:181-201.
|
||
Epub 2023 Oct 13
|
||
doi: 10.1146/annurev-pathmechdis-051122-110348.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37832944" target="_blank">37832944</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33558264">Diffuse Glioma Heterogeneity and Its Therapeutic Implications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nicholson JG,
|
||
Fine HA</span><br />
|
||
<span class="medgenPMjournal">Cancer Discov</span>
|
||
2021 Mar;11(3):575-590.
|
||
Epub 2021 Feb 8
|
||
doi: 10.1158/2159-8290.CD-20-1474.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33558264" target="_blank">33558264</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31227792">Genetic and molecular epidemiology of adult diffuse glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Molinaro AM,
|
||
Taylor JW,
|
||
Wiencke JK,
|
||
Wrensch MR</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Neurol</span>
|
||
2019 Jul;15(7):405-417.
|
||
Epub 2019 Jun 21
|
||
doi: 10.1038/s41582-019-0220-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31227792" target="_blank">31227792</a><a href="/pmc/articles/PMC7286557" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30392758">Epidemiology and Overview of Gliomas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Davis ME</span><br />
|
||
<span class="medgenPMjournal">Semin Oncol Nurs</span>
|
||
2018 Dec;34(5):420-429.
|
||
Epub 2018 Nov 2
|
||
doi: 10.1016/j.soncn.2018.10.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30392758" target="_blank">30392758</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24842956">The epidemiology of glioma in adults: a "state of the science" review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ostrom QT,
|
||
Bauchet L,
|
||
Davis FG,
|
||
Deltour I,
|
||
Fisher JL,
|
||
Langer CE,
|
||
Pekmezci M,
|
||
Schwartzbaum JA,
|
||
Turner MC,
|
||
Walsh KM,
|
||
Wrensch MR,
|
||
Barnholtz-Sloan JS</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2014 Jul;16(7):896-913.
|
||
doi: 10.1093/neuonc/nou087.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24842956" target="_blank">24842956</a><a href="/pmc/articles/PMC4057143" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Glioma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (14019)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37452933">Malignant Glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang LM,
|
||
Englander ZK,
|
||
Miller ML,
|
||
Bruce JN</span><br />
|
||
<span class="medgenPMjournal">Adv Exp Med Biol</span>
|
||
2023;1405:1-30.
|
||
doi: 10.1007/978-3-031-23705-8_1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37452933" target="_blank">37452933</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33791988">Metabolomics of Glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Feng S,
|
||
Liu Y</span><br />
|
||
<span class="medgenPMjournal">Adv Exp Med Biol</span>
|
||
2021;1280:261-276.
|
||
doi: 10.1007/978-3-030-51652-9_18.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33791988" target="_blank">33791988</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31227792">Genetic and molecular epidemiology of adult diffuse glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Molinaro AM,
|
||
Taylor JW,
|
||
Wiencke JK,
|
||
Wrensch MR</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Neurol</span>
|
||
2019 Jul;15(7):405-417.
|
||
Epub 2019 Jun 21
|
||
doi: 10.1038/s41582-019-0220-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31227792" target="_blank">31227792</a><a href="/pmc/articles/PMC7286557" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26948370">Preface.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Berger MS,
|
||
Weller M</span><br />
|
||
<span class="medgenPMjournal">Handb Clin Neurol</span>
|
||
2016;134:ix.
|
||
doi: 10.1016/B978-0-12-802997-8.09988-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26948370" target="_blank">26948370</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22230438">Neuroimaging.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Henson JW,
|
||
Gonzalez RG</span><br />
|
||
<span class="medgenPMjournal">Handb Clin Neurol</span>
|
||
2012;104:109-26.
|
||
doi: 10.1016/B978-0-444-52138-5.00008-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22230438" target="_blank">22230438</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Glioma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (17877)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36566593">Pediatric low-grade glioma: Targeted therapeutics and clinical trials in the molecular era.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Manoharan N,
|
||
Liu KX,
|
||
Mueller S,
|
||
Haas-Kogan DA,
|
||
Bandopadhayay P</span><br />
|
||
<span class="medgenPMjournal">Neoplasia</span>
|
||
2023 Feb;36:100857.
|
||
Epub 2022 Dec 24
|
||
doi: 10.1016/j.neo.2022.100857.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36566593" target="_blank">36566593</a><a href="/pmc/articles/PMC9803951" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33464762">Management of autoimmune encephalitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bien CG</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Neurol</span>
|
||
2021 Apr 1;34(2):166-171.
|
||
doi: 10.1097/WCO.0000000000000909.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33464762" target="_blank">33464762</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28125906">Difluoromethylornithine in cancer: new advances.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alexiou GA,
|
||
Lianos GD,
|
||
Ragos V,
|
||
Galani V,
|
||
Kyritsis AP</span><br />
|
||
<span class="medgenPMjournal">Future Oncol</span>
|
||
2017 Apr;13(9):809-819.
|
||
Epub 2017 Jan 27
|
||
doi: 10.2217/fon-2016-0266.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28125906" target="_blank">28125906</a></div>
|
||
|
||
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<div class="portlet_content ln"><span class="medgenPMauthor">Erker C,
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Tamrazi B,
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<div class="nl"><a target="_blank" href="/pubmed/32502457">Response assessment in paediatric low-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Fangusaro J,
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<div class="nl"><a target="_blank" href="/pubmed/30392758">Epidemiology and Overview of Gliomas.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Glioma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (14787)</a></div></div>
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</div>
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||
<div class="portlet mgSection" id="ID_104">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
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||
<div class="nl"><a target="_blank" href="/pubmed/36271873">Palliative care and end-of-life care in adults with malignant brain tumors.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Koekkoek JAF,
|
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van der Meer PB,
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Pace A,
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Hertler C,
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Harrison R,
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Leeper HE,
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Jalali R,
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Oliver K,
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Philip J,
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Taphoorn MJB,
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Dirven L,
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<span class="bold">PMID: </span><a href="/pubmed/36271873" target="_blank">36271873</a><a href="/pmc/articles/PMC10013651" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/35905783">MicroRNA delivery systems in glioma therapy and perspectives: A systematic review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Jiménez-Morales JM,
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Hernández-Cuenca YE,
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Reyes-Abrahantes A,
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Ruiz-García H,
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Barajas-Olmos F,
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García-Ortiz H,
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Orozco L,
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Quiñones-Hinojosa A,
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<span class="medgenPMjournal">J Control Release</span>
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2022 Sep;349:712-730.
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<span class="bold">PMID: </span><a href="/pubmed/35905783" target="_blank">35905783</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/32027979">Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Efferth T,
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Oesch F</span><br />
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<span class="medgenPMjournal">Semin Cancer Biol</span>
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2022 May;80:39-57.
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Epub 2020 Feb 4
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doi: 10.1016/j.semcancer.2020.01.015.
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<span class="bold">PMID: </span><a href="/pubmed/32027979" target="_blank">32027979</a></div>
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||
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||
<div class="nl"><a target="_blank" href="/pubmed/34302977">Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Wu W,
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Klockow JL,
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Zhang M,
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Lafortune F,
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Chang E,
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Jin L,
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Wu Y,
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<span class="medgenPMjournal">Pharmacol Res</span>
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2021 Sep;171:105780.
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Epub 2021 Jul 21
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doi: 10.1016/j.phrs.2021.105780.
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<span class="bold">PMID: </span><a href="/pubmed/34302977" target="_blank">34302977</a><a href="/pmc/articles/PMC8384724" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33358091">A systematic review of multifocal and multicentric glioblastoma.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Li Y,
|
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Zhang ZX,
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Huang GH,
|
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Xiang Y,
|
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Yang L,
|
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Pei YC,
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Yang W,
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Lv SQ</span><br />
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2021 Jan;83:71-76.
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Epub 2021 Jan 7
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doi: 10.1016/j.jocn.2020.11.025.
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||
<span class="bold">PMID: </span><a href="/pubmed/33358091" target="_blank">33358091</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Glioma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (641)</a></div></div>
|
||
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|
||
</div></div></div></div></div></div></div>
|
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|
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|
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<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
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<div>
|
||
|
||
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0017638%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C0017638%5bDISCUI%5d&filter=method%3A3%5F31" target="_blank">Fluorescence in situ hybridization (FISH) (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C0017638%5bDISCUI%5d&filter=method%3A1%5F3" target="_blank">Immunohistochemistry (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C0017638%5bDISCUI%5d&filter=method%3A2%5F15" target="_blank">Methylation analysis (4)</a></li>
|
||
<li><a href="/gtr/tests?term=C0017638%5bDISCUI%5d&filter=method%3A2%5F18" target="_blank">Mutation scanning of select exons (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0017638%5bDISCUI%5d&filter=method%3A2%5F30" target="_blank">RNA analysis (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0017638%5bDISCUI%5d&filter=method%3A2%5F9" target="_blank">Sequence analysis of select exons (4)</a></li>
|
||
<li><a href="/gtr/tests?term=C0017638%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (8)</a></li>
|
||
<li><a href="/gtr/tests?term=C0017638%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (8)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0017638%5bDISCUI%5d" target="_blank">See all (25)</a></total></li>
|
||
</ul></div>
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</div>
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<div class="portlet mgSection" id="ID_119">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=182067" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Glioma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22glioma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Glioma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/cns.pdf">NCCN, 2023</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Central Nervous System Cancers, 2023</div></li><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng99">NICE, 2021</a><div>UK NICE Guideline NG99, Brain tumours (primary) and brain metastases in over 16s, 2021</div></li><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov//22138009/">NCCN, 2011</a><div>NCCN Task Force report: Evaluating the clinical utility of tumor markers in oncology.</div></li></ul></div>
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