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<!--
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UID=893107
|
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ConceptID=C3805083
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Portal fibrosis</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>893107</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3805083</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Portal fibrosis shown on biopsy</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0006580">HP:0006580</a></td></tr>
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||
<div class="portlet_content ln">Fibroblast proliferation and fiber expansion from the portal areas to the lobule. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Portal fibrosis</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/3828" ref="tree=MeSH" title="MedGen record for Disorder of digestive system">Disorder of digestive system</a></span><ul><li><span class="TLline"><a href="/medgen/78584" ref="tree=MeSH" title="MedGen record for Abnormality of the digestive system">Abnormality of the digestive system</a></span><ul><li><span class="TLline"><a href="/medgen/867396" ref="tree=MeSH" title="MedGen record for Abnormality of the abdominal organs">Abnormality of the abdominal organs</a></span><ul><li><span class="TLline"><a href="/medgen/893061" ref="tree=MeSH" title="MedGen record for Abnormality of the liver">Abnormality of the liver</a></span><ul><li><span class="TLline"><a href="/medgen/184895" ref="tree=MeSH" title="MedGen record for Abnormality of the biliary system">Abnormality of the biliary system</a></span><ul><li><span class="matched_ds">Portal fibrosis</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_42426"><div><strong>Wilson disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>42426</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0019202</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Wilson disease is a disorder of copper metabolism that, when untreated, can present with hepatic, neurologic, or psychiatric disturbances – or a combination of these – in individuals ages three years to older than 70 years. Manifestations in untreated individuals vary among and within families. Liver disease can include recurrent jaundice, simple acute self-limited hepatitis-like illness, autoimmune-type hepatitis, fulminant hepatic failure, or chronic liver disease. Neurologic presentations can include dysarthria, movement disorders (tremors, involuntary movements, chorea, choreoathetosis), dystonia (mask-like facies, rigidity, gait disturbance, pseudobulbar involvement), dysautonomia, seizures, sleep disorders, or insomnia. Psychiatric disturbances can include depression, bipolar disorder / bipolar spectrum disorder, neurotic behaviors, personality changes, or psychosis. Other multisystem involvement can include the eye (Kayser-Fleischer rings), hemolytic anemia, the kidneys, the endocrine glands, and the heart.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/42426">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_78688"><div><strong>Arginase deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>78688</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0268548</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Arginase deficiency in untreated individuals is characterized by episodic hyperammonemia of variable degree that is infrequently severe enough to be life threatening or to cause death. Most commonly, birth and early childhood are normal. Untreated individuals have slowing of linear growth at age one to three years, followed by development of spasticity, plateauing of cognitive development, and subsequent loss of developmental milestones. If untreated, arginase deficiency usually progresses to severe spasticity, loss of ambulation, complete loss of bowel and bladder control, and severe intellectual disability. Seizures are common and are usually controlled easily. Individuals treated from birth, either as a result of newborn screening or having an affected older sib, appear to have minimal symptoms.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/78688">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_340091"><div><strong>Neonatal intrahepatic cholestasis due to citrin deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>340091</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1853942</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Citrin deficiency can manifest in newborns or infants as neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD), in older children as failure to thrive and dyslipidemia caused by citrin deficiency (FTTDCD), and in adults as recurrent hyperammonemia with neuropsychiatric symptoms in citrullinemia type II (CTLN2). Often citrin deficiency is characterized by strong preference for protein-rich and/or lipid-rich foods and aversion to carbohydrate-rich foods. NICCD. Children younger than age one year have a history of low birth weight with growth restriction and transient intrahepatic cholestasis, hepatomegaly, diffuse fatty liver, and parenchymal cellular infiltration associated with hepatic fibrosis, variable liver dysfunction, hypoproteinemia, decreased coagulation factors, hemolytic anemia, and/or hypoglycemia. NICCD is generally not severe and symptoms often resolve by age one year with appropriate treatment, although liver transplantation has been required in rare instances. FTTDCD. Beyond age one year, many children with citrin deficiency develop a protein-rich and/or lipid-rich food preference and aversion to carbohydrate-rich foods. Clinical abnormalities may include growth restriction, hypoglycemia, pancreatitis, severe fatigue, anorexia, and impaired quality of life. Laboratory changes are dyslipidemia, increased lactate-to-pyruvate ratio, higher levels of urinary oxidative stress markers, and considerable deviation in tricarboxylic acid (TCA) cycle metabolites. One or more decades later, some individuals with NICCD or FTTDCD develop CTLN2. CTLN2. Presentation is sudden and usually between ages 20 and 50 years. Manifestations are recurrent hyperammonemia with neuropsychiatric symptoms including nocturnal delirium, aggression, irritability, hyperactivity, delusions, disorientation, restlessness, drowsiness, loss of memory, flapping tremor, convulsive seizures, and coma. Symptoms are often provoked by alcohol and sugar intake, medication, and/or surgery. Affected individuals may or may not have a prior history of NICCD or FTTDCD.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/340091">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_356333"><div><strong>Progressive familial intrahepatic cholestasis type 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>356333</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1865643</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Most people with PFIC3 have signs and symptoms related to liver disease only. Signs and symptoms of PFIC3 usually do not appear until later in infancy or early childhood; rarely, people are diagnosed in early adulthood. Liver failure can occur in childhood or adulthood in people with PFIC3.\n\nThe signs and symptoms of PFIC2 are typically related to liver disease only; however, these signs and symptoms tend to be more severe than those experienced by people with PFIC1. People with PFIC2 often develop liver failure within the first few years of life. Additionally, affected individuals are at increased risk of developing a type of liver cancer called hepatocellular carcinoma.\n\nIn addition to signs and symptoms related to liver disease, people with PFIC1 may have short stature, deafness, diarrhea, inflammation of the pancreas (pancreatitis), and low levels of fat-soluble vitamins (vitamins A, D, E, and K) in the blood. Affected individuals typically develop liver failure before adulthood.\n\nThere are three known types of PFIC: PFIC1, PFIC2, and PFIC3. The types are also sometimes described as shortages of particular proteins needed for normal liver function. Each type has a different genetic cause.\n\nSigns and symptoms of PFIC typically begin in infancy and are related to bile buildup and liver disease. Specifically, affected individuals experience severe itching, yellowing of the skin and whites of the eyes (jaundice), failure to gain weight and grow at the expected rate (failure to thrive), high blood pressure in the vein that supplies blood to the liver (portal hypertension), and an enlarged liver and spleen (hepatosplenomegaly).\n\nProgressive familial intrahepatic cholestasis (PFIC) is a disorder that causes progressive liver disease, which typically leads to liver failure. In people with PFIC, liver cells are less able to secrete a digestive fluid called bile. The buildup of bile in liver cells causes liver disease in affected individuals.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/356333">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_462224"><div><strong>Cranioectodermal dysplasia 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462224</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3150874</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Cranioectodermal dysplasia (CED) is a ciliopathy with skeletal involvement (narrow thorax, shortened proximal limbs, syndactyly, polydactyly, brachydactyly), ectodermal features (widely spaced hypoplastic teeth, hypodontia, sparse hair, skin laxity, abnormal nails), joint laxity, growth deficiency, and characteristic facial features (frontal bossing, low-set simple ears, high forehead, telecanthus, epicanthal folds, full cheeks, everted lower lip). Most affected children develop nephronophthisis that often leads to end-stage kidney disease in infancy or childhood, a major cause of morbidity and mortality. Hepatic fibrosis and retinal dystrophy are also observed. Dolichocephaly, often secondary to sagittal craniosynostosis, is a primary manifestation that distinguishes CED from most other ciliopathies. Brain malformations and developmental delay may also occur.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/462224">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_855697"><div><strong>Nephronophthisis 18</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>855697</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3890591</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Nephronophthisis-18 is an autosomal recessive disorder characterized by chronic tubulointerstitial nephritis resulting in end-stage renal disease in early childhood. Extrarenal manifestations, including intellectual disability or liver changes, may occur in some patients (summary by Failler et al., 2014). For a general phenotypic description and a discussion of genetic heterogeneity of nephronophthisis, see NPHP1 (256100).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/855697">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_904751"><div><strong>Congenital bile acid synthesis defect 5</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>904751</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4225390</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Any congenital bile acid synthesis defect in which the cause of the disease is a mutation in the ABCD3 gene.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/904751">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1393230"><div><strong>Isolated neonatal sclerosing cholangitis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1393230</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4479344</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Neonatal sclerosing cholangitis (NSC) is a rare autosomal recessive form of severe liver disease with onset in infancy. Affected infants have jaundice, cholestasis, acholic stools, and progressive liver dysfunction resulting in fibrosis and cirrhosis; most require liver transplantation in the first few decades of life. Cholangiography shows patent biliary ducts, but there are bile duct irregularities (summary by Girard et al., 2016; Grammatikopoulos et al., 2016).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1393230">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1621383"><div><strong>Extrahepatic biliary atresia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1621383</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4520983</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Biliary atresia is a disorder of infants in which there is progressive obliteration or discontinuity of the extrahepatic biliary system, resulting in obstruction of bile flow. Untreated, the resulting cholestasis leads to progressive conjugated hyperbilirubinemia, cirrhosis, and hepatic failure (Bates et al., 1998). Most patients require liver transplantation within the first year of life (Leyva-Vega et al., 2010). See also Alagille syndrome (118450), which includes biliary atresia as a feature.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1621383">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1632232"><div><strong>Adenosine kinase deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1632232</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4706555</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hypermethioninemia due to adenosine kinase deficiency is an autosomal recessive inborn error of metabolism characterized by global developmental delay, early-onset seizures, mild dysmorphic features, and characteristic biochemical anomalies, including persistent hypermethioninemia with increased levels of S-adenosylmethionine (AdoMet) and S-adenosylhomocysteine (AdoHcy); homocysteine is typically normal (summary by Bjursell et al., 2011).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1632232">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1752166"><div><strong>COACH syndrome 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1752166</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5436837</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">COACH syndrome is classically defined as Cerebellar vermis hypoplasia, Oligophrenia, Ataxia, Colobomas, and Hepatic fibrosis (Verloes and Lambotte, 1989). Brain MRI demonstrates the molar tooth sign, which is a feature of Joubert syndrome. The disorder has been described as a Joubert syndrome-related disorder with liver disease (summary by Doherty et al., 2010). For a general phenotypic description and a discussion of genetic heterogeneity of COACH syndrome, see 216360.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1752166">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1755565"><div><strong>COACH syndrome 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1755565</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5436841</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">COACH syndrome is classically defined as Cerebellar vermis hypoplasia, Oligophrenia, Ataxia, Colobomas, and Hepatic fibrosis (Verloes and Lambotte, 1989). Brain MRI demonstrates the molar tooth sign, which is a feature of Joubert syndrome. The disorder has been described as a Joubert syndrome-related disorder with liver disease (summary by Doherty et al., 2010). For a general phenotypic description and a discussion of genetic heterogeneity of COACH syndrome, see 216360.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1755565">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1785846"><div><strong>Osteootohepatoenteric syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1785846</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543557</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Osteootohepatoenteric syndrome (OOHE) is characterized by a variable combination of bone fragility, hearing loss, cholestasis, and congenital diarrhea. Some patients also display mild developmental delay and intellectual disability (Esteve et al., 2018).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1785846">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1807702"><div><strong>Cholestasis, progressive familial intrahepatic, 10</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1807702</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5676981</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Progressive familial intrahepatic cholestasis-10 (PFIC10) is an autosomal recessive liver disorder characterized by the onset of symptoms in the first months or years of life. Features include jaundice, pruritis, and hepatomegaly associated with increased serum bilirubin and bile acids. Liver transaminases may be variably increased, but gamma-glutamyltransferase (GGT; see 612346) is normal. Liver biopsy shows hepatocellular and canalicular cholestasis with giant cell changes. Although rare patients may have episodes of diarrhea and even show endoscopic features of microvillus inclusion disease (MVID), this tends to be transient and cholestasis dominates the clinical picture (Gonzales et al., 2017; Cockar et al., 2020). For a discussion of genetic heterogeneity of progressive familial intrahepatic cholestasis, see PFIC1 (211600).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1807702">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1632232" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Adenosine kinase deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_78688" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Arginase deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1807702" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cholestasis, progressive familial intrahepatic, 10</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1752166" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">COACH syndrome 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1755565" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">COACH syndrome 3</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (14)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_904751" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Congenital bile acid synthesis defect 5</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462224" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cranioectodermal dysplasia 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1621383" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Extrahepatic biliary atresia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1393230" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Isolated neonatal sclerosing cholangitis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_340091" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neonatal intrahepatic cholestasis due to citrin deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_855697" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Nephronophthisis 18</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1785846" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Osteootohepatoenteric syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_356333" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Progressive familial intrahepatic cholestasis type 3</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_42426" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Wilson disease</a></div></span></div></div>
|
||
</div>
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||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/26593297">Total Parenteral Nutrition-Induced Cholestasis: Prevention and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Beath SV,
|
||
Kelly DA</span><br />
|
||
<span class="medgenPMjournal">Clin Liver Dis</span>
|
||
2016 Feb;20(1):159-76.
|
||
Epub 2015 Oct 9
|
||
doi: 10.1016/j.cld.2015.08.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26593297" target="_blank">26593297</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23978714">Non-cirrhotic portal hypertension - diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khanna R,
|
||
Sarin SK</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
2014 Feb;60(2):421-41.
|
||
Epub 2013 Aug 23
|
||
doi: 10.1016/j.jhep.2013.08.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23978714" target="_blank">23978714</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19940839">Genotype-phenotype correlations in fetuses and neonates with autosomal recessive polycystic kidney disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Denamur E,
|
||
Delezoide AL,
|
||
Alberti C,
|
||
Bourillon A,
|
||
Gubler MC,
|
||
Bouvier R,
|
||
Pascaud O,
|
||
Elion J,
|
||
Grandchamp B,
|
||
Michel-Calemard L,
|
||
Missy P,
|
||
Zaccaria I,
|
||
Le Nagard H,
|
||
Gerard B,
|
||
Loirat C;
|
||
Société Française de Foetopathologie,
|
||
Barbet J,
|
||
Beaufrère AM,
|
||
Berchel C,
|
||
Bessières B,
|
||
Boudjemaa S,
|
||
Buenerd A,
|
||
Carles D,
|
||
Clemenson A,
|
||
Dechelotte P,
|
||
Devisme L,
|
||
Dijoud F,
|
||
Espérandieu O,
|
||
Fallet C,
|
||
Gonzalès M,
|
||
Hillion Y,
|
||
Jacob B,
|
||
Joubert M,
|
||
Kermanach P,
|
||
Lallemand A,
|
||
Laquerrière A,
|
||
Laurent N,
|
||
Liprandi A,
|
||
Loeuillet L,
|
||
Loget P,
|
||
Martinovic J,
|
||
Ménez F,
|
||
Narcy F,
|
||
Roux JJ,
|
||
Rouleau-Dubois C,
|
||
Sinico M,
|
||
Tantau J,
|
||
Wann AR</span><br />
|
||
<span class="medgenPMjournal">Kidney Int</span>
|
||
2010 Feb;77(4):350-8.
|
||
Epub 2009 Nov 25
|
||
doi: 10.1038/ki.2009.440.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19940839" target="_blank">19940839</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22portal%20fibrosis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (35)</a></div></div>
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</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/23978714">Non-cirrhotic portal hypertension - diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khanna R,
|
||
Sarin SK</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
2014 Feb;60(2):421-41.
|
||
Epub 2013 Aug 23
|
||
doi: 10.1016/j.jhep.2013.08.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23978714" target="_blank">23978714</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23180936">Portal biliopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chattopadhyay S,
|
||
Nundy S</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
||
2012 Nov 21;18(43):6177-82.
|
||
doi: 10.3748/wjg.v18.i43.6177.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23180936" target="_blank">23180936</a><a href="/pmc/articles/PMC3501764" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17162232">Noncirrhotic portal hypertension.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sarin SK,
|
||
Kumar A</span><br />
|
||
<span class="medgenPMjournal">Clin Liver Dis</span>
|
||
2006 Aug;10(3):627-51, x.
|
||
doi: 10.1016/j.cld.2006.08.021.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17162232" target="_blank">17162232</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10484010">Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brunt EM,
|
||
Janney CG,
|
||
Di Bisceglie AM,
|
||
Neuschwander-Tetri BA,
|
||
Bacon BR</span><br />
|
||
<span class="medgenPMjournal">Am J Gastroenterol</span>
|
||
1999 Sep;94(9):2467-74.
|
||
doi: 10.1111/j.1572-0241.1999.01377.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10484010" target="_blank">10484010</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3669114">Arsenicosis in India.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Narang AP</span><br />
|
||
<span class="medgenPMjournal">J Toxicol Clin Toxicol</span>
|
||
1987;25(4):287-95.
|
||
doi: 10.3109/15563658708992632.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3669114" target="_blank">3669114</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Portal%20fibrosis%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (292)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31405536">Idiopathic noncirrhotic portal hypertension.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fiel MI,
|
||
Schiano TD</span><br />
|
||
<span class="medgenPMjournal">Semin Diagn Pathol</span>
|
||
2019 Nov;36(6):395-403.
|
||
Epub 2019 Jul 24
|
||
doi: 10.1053/j.semdp.2019.07.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31405536" target="_blank">31405536</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28631037">Inclusion bodies of aggregated hemosiderins in liver macrophages.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hayashi H,
|
||
Tatsumi Y,
|
||
Wakusawa S,
|
||
Shigemasa R,
|
||
Koide R,
|
||
Tsuchida KI,
|
||
Morotomi N,
|
||
Yamashita T,
|
||
Kumagai K,
|
||
Ono Y,
|
||
Hayashi K,
|
||
Ishigami M,
|
||
Goto H,
|
||
Kato A,
|
||
Kato K</span><br />
|
||
<span class="medgenPMjournal">Med Mol Morphol</span>
|
||
2017 Dec;50(4):205-210.
|
||
Epub 2017 Jun 19
|
||
doi: 10.1007/s00795-017-0163-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28631037" target="_blank">28631037</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23978714">Non-cirrhotic portal hypertension - diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khanna R,
|
||
Sarin SK</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
2014 Feb;60(2):421-41.
|
||
Epub 2013 Aug 23
|
||
doi: 10.1016/j.jhep.2013.08.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23978714" target="_blank">23978714</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23180936">Portal biliopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chattopadhyay S,
|
||
Nundy S</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
||
2012 Nov 21;18(43):6177-82.
|
||
doi: 10.3748/wjg.v18.i43.6177.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23180936" target="_blank">23180936</a><a href="/pmc/articles/PMC3501764" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17162232">Noncirrhotic portal hypertension.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sarin SK,
|
||
Kumar A</span><br />
|
||
<span class="medgenPMjournal">Clin Liver Dis</span>
|
||
2006 Aug;10(3):627-51, x.
|
||
doi: 10.1016/j.cld.2006.08.021.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17162232" target="_blank">17162232</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Portal%20fibrosis%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (255)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35802227">Maternal and perinatal outcome in pregnancies complicated with portal hypertension: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pal K,
|
||
Sadanandan DM,
|
||
Gupta A,
|
||
Nayak D,
|
||
Pyakurel M,
|
||
Keepanasseril A,
|
||
Maurya DK,
|
||
Nair NS,
|
||
Keepanasseril A</span><br />
|
||
<span class="medgenPMjournal">Hepatol Int</span>
|
||
2023 Feb;17(1):170-179.
|
||
Epub 2022 Jul 8
|
||
doi: 10.1007/s12072-022-10385-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35802227" target="_blank">35802227</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35331404">Long-term outcomes of biliary atresia patients surviving with their native livers.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hukkinen M,
|
||
Ruuska S,
|
||
Pihlajoki M,
|
||
Kyrönlahti A,
|
||
Pakarinen MP</span><br />
|
||
<span class="medgenPMjournal">Best Pract Res Clin Gastroenterol</span>
|
||
2022 Feb-Mar;56-57:101764.
|
||
Epub 2021 Sep 4
|
||
doi: 10.1016/j.bpg.2021.101764.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35331404" target="_blank">35331404</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12382201">African iron overload.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gordeuk VR</span><br />
|
||
<span class="medgenPMjournal">Semin Hematol</span>
|
||
2002 Oct;39(4):263-9.
|
||
doi: 10.1053/shem.2002.35636.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12382201" target="_blank">12382201</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7647282">Fibrosing cholestatic hepatitis and HBV after bone marrow transplantation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cooksley WG,
|
||
McIvor CA</span><br />
|
||
<span class="medgenPMjournal">Biomed Pharmacother</span>
|
||
1995;49(3):117-24.
|
||
doi: 10.1016/0753-3322(96)82604-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7647282" target="_blank">7647282</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1086057">Idiopathic portal hypertension.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Villeneuve JP,
|
||
Huet PM,
|
||
Joly JG,
|
||
Marleau D,
|
||
Côté J,
|
||
Légaré A,
|
||
Lafortune M,
|
||
Lavoie P,
|
||
Viallet A</span><br />
|
||
<span class="medgenPMjournal">Am J Med</span>
|
||
1976 Oct;61(4):459-64.
|
||
doi: 10.1016/0002-9343(76)90323-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1086057" target="_blank">1086057</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Portal%20fibrosis%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (180)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/24679506">Non-cirrhotic portal hypertension.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sarin SK,
|
||
Khanna R</span><br />
|
||
<span class="medgenPMjournal">Clin Liver Dis</span>
|
||
2014 May;18(2):451-76.
|
||
doi: 10.1016/j.cld.2014.01.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24679506" target="_blank">24679506</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23978714">Non-cirrhotic portal hypertension - diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khanna R,
|
||
Sarin SK</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
2014 Feb;60(2):421-41.
|
||
Epub 2013 Aug 23
|
||
doi: 10.1016/j.jhep.2013.08.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23978714" target="_blank">23978714</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23180936">Portal biliopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chattopadhyay S,
|
||
Nundy S</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
||
2012 Nov 21;18(43):6177-82.
|
||
doi: 10.3748/wjg.v18.i43.6177.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23180936" target="_blank">23180936</a><a href="/pmc/articles/PMC3501764" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19940839">Genotype-phenotype correlations in fetuses and neonates with autosomal recessive polycystic kidney disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Denamur E,
|
||
Delezoide AL,
|
||
Alberti C,
|
||
Bourillon A,
|
||
Gubler MC,
|
||
Bouvier R,
|
||
Pascaud O,
|
||
Elion J,
|
||
Grandchamp B,
|
||
Michel-Calemard L,
|
||
Missy P,
|
||
Zaccaria I,
|
||
Le Nagard H,
|
||
Gerard B,
|
||
Loirat C;
|
||
Société Française de Foetopathologie,
|
||
Barbet J,
|
||
Beaufrère AM,
|
||
Berchel C,
|
||
Bessières B,
|
||
Boudjemaa S,
|
||
Buenerd A,
|
||
Carles D,
|
||
Clemenson A,
|
||
Dechelotte P,
|
||
Devisme L,
|
||
Dijoud F,
|
||
Espérandieu O,
|
||
Fallet C,
|
||
Gonzalès M,
|
||
Hillion Y,
|
||
Jacob B,
|
||
Joubert M,
|
||
Kermanach P,
|
||
Lallemand A,
|
||
Laquerrière A,
|
||
Laurent N,
|
||
Liprandi A,
|
||
Loeuillet L,
|
||
Loget P,
|
||
Martinovic J,
|
||
Ménez F,
|
||
Narcy F,
|
||
Roux JJ,
|
||
Rouleau-Dubois C,
|
||
Sinico M,
|
||
Tantau J,
|
||
Wann AR</span><br />
|
||
<span class="medgenPMjournal">Kidney Int</span>
|
||
2010 Feb;77(4):350-8.
|
||
Epub 2009 Nov 25
|
||
doi: 10.1038/ki.2009.440.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19940839" target="_blank">19940839</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12472939">Non-cirrhotic portal fibrosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sarin SK</span><br />
|
||
<span class="medgenPMjournal">J Gastroenterol Hepatol</span>
|
||
2002 Dec;17 Suppl 3:S214-23.
|
||
doi: 10.1046/j.1440-1746.17.s3.3.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12472939" target="_blank">12472939</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Portal%20fibrosis%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (187)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/27160101">An Observation from Liver Biopsies Two Decades Post-Fontan.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Evans WN,
|
||
Acherman RJ,
|
||
Reardon LC,
|
||
Galindo A,
|
||
Rothman A,
|
||
Ciccolo ML,
|
||
Carrillo SA,
|
||
Winn BJ,
|
||
Yumiaco NS,
|
||
Restrepo H</span><br />
|
||
<span class="medgenPMjournal">Pediatr Cardiol</span>
|
||
2016 Aug;37(6):1119-22.
|
||
Epub 2016 May 9
|
||
doi: 10.1007/s00246-016-1403-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27160101" target="_blank">27160101</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23180936">Portal biliopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chattopadhyay S,
|
||
Nundy S</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
||
2012 Nov 21;18(43):6177-82.
|
||
doi: 10.3748/wjg.v18.i43.6177.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23180936" target="_blank">23180936</a><a href="/pmc/articles/PMC3501764" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15750923">Kasai portoenterostomy--new insights from hepatic morphology.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hussein A,
|
||
Wyatt J,
|
||
Guthrie A,
|
||
Stringer MD</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Surg</span>
|
||
2005 Feb;40(2):322-6.
|
||
doi: 10.1016/j.jpedsurg.2004.10.018.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15750923" target="_blank">15750923</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12382201">African iron overload.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gordeuk VR</span><br />
|
||
<span class="medgenPMjournal">Semin Hematol</span>
|
||
2002 Oct;39(4):263-9.
|
||
doi: 10.1053/shem.2002.35636.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12382201" target="_blank">12382201</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10484010">Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brunt EM,
|
||
Janney CG,
|
||
Di Bisceglie AM,
|
||
Neuschwander-Tetri BA,
|
||
Bacon BR</span><br />
|
||
<span class="medgenPMjournal">Am J Gastroenterol</span>
|
||
1999 Sep;94(9):2467-74.
|
||
doi: 10.1111/j.1572-0241.1999.01377.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10484010" target="_blank">10484010</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Portal%20fibrosis%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (197)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/39053026">Histopathological features of idiopathic portal hypertension: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Malik A,
|
||
Malik S,
|
||
Farooq A,
|
||
Malik MI,
|
||
Javaid S</span><br />
|
||
<span class="medgenPMjournal">Sci Prog</span>
|
||
2024 Jul-Sep;107(3):368504241264996.
|
||
doi: 10.1177/00368504241264996.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39053026" target="_blank">39053026</a><a href="/pmc/articles/PMC11282518" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37119294">Noninvasive differentiation of porto-sinusoidal vascular disorder from cirrhosis: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Giri S,
|
||
Singh A,
|
||
Roy A,
|
||
Patel RK,
|
||
Tripathy T,
|
||
Angadi S</span><br />
|
||
<span class="medgenPMjournal">Abdom Radiol (NY)</span>
|
||
2023 Jul;48(7):2340-2348.
|
||
Epub 2023 Apr 29
|
||
doi: 10.1007/s00261-023-03927-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37119294" target="_blank">37119294</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35802227">Maternal and perinatal outcome in pregnancies complicated with portal hypertension: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pal K,
|
||
Sadanandan DM,
|
||
Gupta A,
|
||
Nayak D,
|
||
Pyakurel M,
|
||
Keepanasseril A,
|
||
Maurya DK,
|
||
Nair NS,
|
||
Keepanasseril A</span><br />
|
||
<span class="medgenPMjournal">Hepatol Int</span>
|
||
2023 Feb;17(1):170-179.
|
||
Epub 2022 Jul 8
|
||
doi: 10.1007/s12072-022-10385-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35802227" target="_blank">35802227</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Portal%20fibrosis%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div></div>
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