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<meta name="keywords" content="C0339182, adhesion of eyelids, anatomical abnormality, ankyloblepharon, ankyloblepharon filiforme adnatum, eyelid synechiae, eyelids stuck together, fused eyelid, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Partial fusion of the upper and lower eyelid margins by single or multiple bands of tissue." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Ankyloblepharon (Concept Id: C0339182)
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<!--
UID=83282
ConceptID=C0339182
-->
<!--imgCountBooks = 0--><div class="ncbi_carousel" data-ncbicarousel-config="imageWidth:'100px',numItemsVisible:2,toggler:false"><div class="nc_header"><span class="img_strip_title">Image</span></div><div class="nc_content"><div class="nc_item"><a class="figpopup"><img alt="Figure 1" src="/projects/medgen/images/thumb/9aefd466e74d3204.1.thumb.jpg" src-large="/projects/medgen/images/9aefd466e74d3204.1.jpg" /></a><br /><a href="http://elementsofmorphology.nih.gov/index.cgi?tid=9aefd466e74d3204" target="_blank" title="Elements of Morphology: Human Malformation Terminology - NHGRI">details</a></div></div></div><h1 class="medgenTitle"><div class="MedGenTitleText">Ankyloblepharon</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>83282</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0339182</a></dd><dt><span class="dotprefix"></span></dt><dd>Anatomical Abnormality</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Adhesion of eyelids; Ankyloblepharon filiforme adnatum; Eyelid synechiae; Eyelids stuck together; Fused eyelid</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Ankyloblepharon (193953008)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0009755">HP:0009755</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Partial fusion of the upper and lower eyelid margins by single or multiple bands of tissue. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Ankyloblepharon</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867438" ref="tree=MeSH" title="MedGen record for Abnormality of the head">Abnormality of the head</a></span><ul><li><span class="TLline"><a href="/medgen/871375" ref="tree=MeSH" title="MedGen record for Abnormality of the face">Abnormality of the face</a></span><ul><li><span class="TLline"><a href="/medgen/871367" ref="tree=MeSH" title="MedGen record for Abnormality of the orbital region">Abnormality of the orbital region</a></span><ul><li><span class="TLline"><a href="/medgen/1670962" ref="tree=MeSH" title="MedGen record for Abnormality of the ocular adnexa">Abnormality of the ocular adnexa</a></span><ul><li><span class="TLline"><a href="/medgen/893067" ref="tree=MeSH" title="MedGen record for Abnormal ocular adnexa morphology">Abnormal ocular adnexa morphology</a></span><ul><li><span class="TLline"><a href="/medgen/867429" ref="tree=MeSH" title="MedGen record for Abnormal eyelid morphology">Abnormal eyelid morphology</a></span><ul><li><span class="matched_ds">Ankyloblepharon</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_98032"><div><strong>Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98032</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0406709</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">The TP63-related disorders comprise six overlapping phenotypes: Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome (which includes Rapp-Hodgkin syndrome). Acro-dermo-ungual-lacrimal-tooth (ADULT) syndrome. Ectrodactyly, ectodermal dysplasia, cleft lip/palate syndrome 3 (EEC3). Limb-mammary syndrome. Split-hand/foot malformation type 4 (SHFM4). Isolated cleft lip/cleft palate (orofacial cleft 8). Individuals typically have varying combinations of ectodermal dysplasia (hypohidrosis, nail dysplasia, sparse hair, tooth abnormalities), cleft lip/palate, split-hand/foot malformation/syndactyly, lacrimal duct obstruction, hypopigmentation, hypoplastic breasts and/or nipples, and hypospadias. Findings associated with a single phenotype include ankyloblepharon filiforme adnatum (tissue strands that completely or partially fuse the upper and lower eyelids), skin erosions especially on the scalp associated with areas of scarring, and alopecia, trismus, and excessive freckling.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/98032">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_98035"><div><strong>Curly hair, ankyloblepharon, nail dysplasia syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98035</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0406733</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">CHAND syndrome is characterized by ankyloblepharon, sparse, curly, and woolly hair, nail dysplasia, and oral frenula (summary by Busa et al., 2017).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/98035">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_337894"><div><strong>Bartsocas-Papas syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>337894</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1849718</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Bartsocas-Papas syndrome-1 (BPS1) is an autosomal recessive disorder characterized by multiple popliteal pterygia, ankyloblepharon, filiform bands between the jaws, cleft lip and palate, and syndactyly. Early lethality is common, although survival into childhood and beyond has been reported (summary by Mitchell et al., 2012).&#13; Genetic Heterogeneity of Bartsocas-Papas Syndrome&#13; Bartsocas-Papas syndrome-2 (BPS2) is caused by mutation in the CHUK gene (600664).&#13; A less severe form of popliteal pterygium syndrome (PPS; 119500) is caused by mutation in the IRF6 gene (607199).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/337894">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_342242"><div><strong>Isolated cryptophthalmia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>342242</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1852453</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Cryptophthalmos is a condition of eyelid malformation with an underlying malformed eye. Complete, incomplete, and symblepharon varieties exist. The skin in complete cryptophthalmos extends uninterrupted from the forehead to the cheek. In the incomplete form, there is medial eyelid fusion, but coincident intact lateral structures. The symblepharon variety presents with fusion of the upper eyelid skin to the superior aspect of the globe. The complete variety is the most common form (summary by Egier et al., 2005).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/342242">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_400148"><div><strong>Ankyloblepharon filiforme adnatum-cleft palate syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>400148</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1862866</a></dd><dt><span class="dotprefix"></span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
<div class="spaceAbove">A rare syndromic developmental defect of the eye malformation with characteristics of unilateral or bilateral, single or multiple, filiforme bands of elastic tissue which connect the eyelid margins at the gray line, associated with cleft lip and palate. Eye examination is otherwise normal.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/400148">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_390740"><div><strong>Endocrine-cerebro-osteodysplasia syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>390740</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C2675227</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Endocrine-cerebro-osteodysplasia (ECO) syndrome is characterized by various anomalies of the endocrine, cerebral, and skeletal systems resulting in neonatal mortality.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/390740">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_444125"><div><strong>Gollop syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>444125</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C2931720</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">The features of frontofacionasal dysplasia include blepharophimosis, lower lid lagophthalmos, primary telecanthus, S-shaped palpebral fissures, facial hypoplasia, eyelid coloboma, widow's peak, cranium bifidum occultum, frontal lipoma, nasal hypoplasia, deformed nostrils, bifid nose, and cleft of lip, premaxilla, palate, and uvula (White et al., 1991). Also see frontonasal dysplasia (136760).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/444125">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1778443"><div><strong>Bartsocas-Papas syndrome 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1778443</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5543445</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Bartsocas-Papas syndrome-2 (BPS2) is a severe form of popliteal pterygium disorder characterized by cutaneous webbing across one or more joints, cleft lip and/or palate, syndactyly, and genital malformations (summary by Leslie et al., 2015).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1778443">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1823955"><div><strong>Isolated microphthalmia 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1823955</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5774181</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Syndromic microphthalmia-16 (MCOPS16) is characterized by bilateral severe microphthalmia or anophthalmia with variable presence of midline defects, including cleft lip and palate, absence of frontal and/or sphenoidal sinuses, and absent pituitary gland. Some patients exhibit developmental delay and intellectual disability or autism (Voronina et al., 2004; Abouzeid et al., 2012; Chassaing et al., 2014; Brachet et al., 2019).&#13; For discussion of the genetic heterogeneity of syndromic microphthalmia, see MCOPS1 (309800).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1823955">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1844082"><div><strong>Autosomal dominant popliteal pterygium syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1844082</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5848052</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Most commonly, IRF6-related disorders span a spectrum from isolated cleft lip and palate and Van der Woude syndrome (VWS) at the mild end to popliteal pterygium syndrome (PPS) at the more severe end. In rare instances, IRF6 pathogenic variants have also been reported in individuals with nonsyndromic orofacial cleft (18/3,811; 0.47%) and in individuals with spina bifida (2/192). Individuals with VWS show one or more of the following anomalies: Congenital, usually bilateral, paramedian lower-lip fistulae (pits) or sometimes small mounds with a sinus tract leading from a mucous gland of the lip. Cleft lip (CL). Cleft palate (CP). Note: Cleft lip with or without cleft palate (CL±P) is observed about twice as often as CP only. Submucous cleft palate (SMCP). The PPS phenotype includes the following: CL±P. Fistulae of the lower lip. Webbing of the skin extending from the ischial tuberosities to the heels. In males: bifid scrotum and cryptorchidism. In females: hypoplasia of the labia majora. Syndactyly of fingers and/or toes. Anomalies of the skin around the nails. A characteristic pyramidal fold of skin overlying the nail of the hallux (almost pathognomonic). In some nonclassic forms of PPS: filiform synechiae connecting the upper and lower jaws (syngnathia) or the upper and lower eyelids (ankyloblepharon). Other musculoskeletal anomalies may include spina bifida occulta, talipes equinovarus, digital reduction, bifid ribs, and short sternum. In VWS, PPS, IRF6-related neural tube defect, and IRF6-related orofacial cleft, growth and intelligence are typical.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1844082">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_400148" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ankyloblepharon filiforme adnatum-cleft palate syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_98032" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1844082" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal dominant popliteal pterygium syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_337894" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Bartsocas-Papas syndrome 1</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1778443" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Bartsocas-Papas syndrome 2</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (10)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_98035" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Curly hair, ankyloblepharon, nail dysplasia syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_390740" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Endocrine-cerebro-osteodysplasia syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_444125" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Gollop syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_342242" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Isolated cryptophthalmia</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1823955" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Isolated microphthalmia 3</a></div></span></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/35535356">Perioperative Management and Long-Term Outcomes in Ocular Cicatricial Pemphigoid Patients Undergoing Cataract Surgery.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">He Y,
Quan Z,
Zhang R,
Ji Z,
Jia J,
Liu H,
Zhang C,
He B,
Ren Y,
Feng Y</span><br />
<span class="medgenPMjournal">Oxid Med Cell Longev</span>
2022;2022:2496649.
Epub 2022 Apr 30
doi: 10.1155/2022/2496649.
<span class="bold">PMID: </span><a href="/pubmed/35535356" target="_blank">35535356</a><a href="/pmc/articles/PMC9078804" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28691991">Intraoperative Mitomycin C in the Treatment of Recalcitrant Ankyloblepharon.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Vahdani K,
Mcveigh K,
Tavassoli S,
Garrott H,
Ford R,
Collin R</span><br />
<span class="medgenPMjournal">Ophthalmic Plast Reconstr Surg</span>
2017 Jul/Aug;33(4):312-313.
doi: 10.1097/IOP.0000000000000915.
<span class="bold">PMID: </span><a href="/pubmed/28691991" target="_blank">28691991</a></div>
<div class="nl"><a target="_blank" href="/pubmed/3561941">More of the conservative management of cyanoacrylate ankyloblepharon.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Donnenfeld ED,
Perry HD,
Nelson DB</span><br />
<span class="medgenPMjournal">Ophthalmic Surg</span>
1987 Jan;18(1):74-5.
<span class="bold">PMID: </span><a href="/pubmed/3561941" target="_blank">3561941</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22ankyloblepharon%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (6)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/35170449">Simple surgical approach for treatment of ankyloblepharon filiforme adnatum: A case report.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Akagun N</span><br />
<span class="medgenPMjournal">Niger J Clin Pract</span>
2022 Feb;25(2):203-204.
doi: 10.4103/njcp.njcp_571_20.
<span class="bold">PMID: </span><a href="/pubmed/35170449" target="_blank">35170449</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35130400">TP63-related disorders: two case reports and a brief review of the literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nanda A,
AlLafi A,
Wolf S,
AlMasry IM,
Betz R</span><br />
<span class="medgenPMjournal">Dermatol Online J</span>
2021 Nov 15;27(11)
doi: 10.5070/D3271156088.
<span class="bold">PMID: </span><a href="/pubmed/35130400" target="_blank">35130400</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33933124">Ocular manifestations of ectodermal dysplasia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Landau Prat D,
Katowitz WR,
Strong A,
Katowitz JA</span><br />
<span class="medgenPMjournal">Orphanet J Rare Dis</span>
2021 May 1;16(1):197.
doi: 10.1186/s13023-021-01824-2.
<span class="bold">PMID: </span><a href="/pubmed/33933124" target="_blank">33933124</a><a href="/pmc/articles/PMC8088613" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/18633439">IKKalpha is a p63 transcriptional target involved in the pathogenesis of ectodermal dysplasias.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Marinari B,
Ballaro C,
Koster MI,
Giustizieri ML,
Moretti F,
Crosti F,
Papoutsaki M,
Karin M,
Alema S,
Chimenti S,
Roop DR,
Costanzo A</span><br />
<span class="medgenPMjournal">J Invest Dermatol</span>
2009 Jan;129(1):60-9.
Epub 2008 Jul 17
doi: 10.1038/jid.2008.202.
<span class="bold">PMID: </span><a href="/pubmed/18633439" target="_blank">18633439</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12692135">P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Fomenkov A,
Huang YP,
Topaloglu O,
Brechman A,
Osada M,
Fomenkova T,
Yuriditsky E,
Trink B,
Sidransky D,
Ratovitski E</span><br />
<span class="medgenPMjournal">J Biol Chem</span>
2003 Jun 27;278(26):23906-14.
Epub 2003 Apr 10
doi: 10.1074/jbc.M300746200.
<span class="bold">PMID: </span><a href="/pubmed/12692135" target="_blank">12692135</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ankyloblepharon%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (33)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/35130400">TP63-related disorders: two case reports and a brief review of the literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nanda A,
AlLafi A,
Wolf S,
AlMasry IM,
Betz R</span><br />
<span class="medgenPMjournal">Dermatol Online J</span>
2021 Nov 15;27(11)
doi: 10.5070/D3271156088.
<span class="bold">PMID: </span><a href="/pubmed/35130400" target="_blank">35130400</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32611653">Multidisciplinary management of ankyloblepharon filiforme adnatum.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Armes H,
Williams SA,
Dunne J,
Eccles SJ</span><br />
<span class="medgenPMjournal">BMJ Case Rep</span>
2020 Jul 1;13(7)
doi: 10.1136/bcr-2020-234249.
<span class="bold">PMID: </span><a href="/pubmed/32611653" target="_blank">32611653</a><a href="/pmc/articles/PMC7332181" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29305408">Ankyloblepharon filiforme adnatum.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Elbashier SE,
Zakharchenko L,
Boyle MA</span><br />
<span class="medgenPMjournal">Arch Dis Child Fetal Neonatal Ed</span>
2018 May;103(3):F207.
Epub 2018 Jan 5
doi: 10.1136/archdischild-2017-313932.
<span class="bold">PMID: </span><a href="/pubmed/29305408" target="_blank">29305408</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21299053">Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome in monozygotic twins: two cases report and reviews.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jenwitheesuk K,
Surakunprapha P,
Chowchuen B,
Jetsrisuparb C</span><br />
<span class="medgenPMjournal">J Med Assoc Thai</span>
2010 Oct;93 Suppl 4:S78-82.
<span class="bold">PMID: </span><a href="/pubmed/21299053" target="_blank">21299053</a></div>
<div class="nl"><a target="_blank" href="/pubmed/3809025">Hay-Wells syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shwayder TA,
Lane AT,
Miller ME</span><br />
<span class="medgenPMjournal">Pediatr Dermatol</span>
1986 Nov;3(5):399-402.
doi: 10.1111/j.1525-1470.1986.tb00549.x.
<span class="bold">PMID: </span><a href="/pubmed/3809025" target="_blank">3809025</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ankyloblepharon%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (83)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/35535356">Perioperative Management and Long-Term Outcomes in Ocular Cicatricial Pemphigoid Patients Undergoing Cataract Surgery.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">He Y,
Quan Z,
Zhang R,
Ji Z,
Jia J,
Liu H,
Zhang C,
He B,
Ren Y,
Feng Y</span><br />
<span class="medgenPMjournal">Oxid Med Cell Longev</span>
2022;2022:2496649.
Epub 2022 Apr 30
doi: 10.1155/2022/2496649.
<span class="bold">PMID: </span><a href="/pubmed/35535356" target="_blank">35535356</a><a href="/pmc/articles/PMC9078804" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32611653">Multidisciplinary management of ankyloblepharon filiforme adnatum.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Armes H,
Williams SA,
Dunne J,
Eccles SJ</span><br />
<span class="medgenPMjournal">BMJ Case Rep</span>
2020 Jul 1;13(7)
doi: 10.1136/bcr-2020-234249.
<span class="bold">PMID: </span><a href="/pubmed/32611653" target="_blank">32611653</a><a href="/pmc/articles/PMC7332181" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30088137">Sweating ability of patients with p63-associated syndromes.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ferstl P,
Wohlfart S,
Schneider H</span><br />
<span class="medgenPMjournal">Eur J Pediatr</span>
2018 Nov;177(11):1727-1731.
Epub 2018 Aug 7
doi: 10.1007/s00431-018-3227-6.
<span class="bold">PMID: </span><a href="/pubmed/30088137" target="_blank">30088137</a></div>
<div class="nl"><a target="_blank" href="/pubmed/2199891">Cicatricial pemphigoid and erythema multiforme.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mondino BJ</span><br />
<span class="medgenPMjournal">Ophthalmology</span>
1990 Jul;97(7):939-52.
doi: 10.1016/s0161-6420(90)32479-x.
<span class="bold">PMID: </span><a href="/pubmed/2199891" target="_blank">2199891</a></div>
<div class="nl"><a target="_blank" href="/pubmed/3688719">Ankyloblepharon associated with systemic 5-fluorouracil treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Insler MS,
Helm CJ</span><br />
<span class="medgenPMjournal">Ann Ophthalmol</span>
1987 Oct;19(10):374-5.
<span class="bold">PMID: </span><a href="/pubmed/3688719" target="_blank">3688719</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ankyloblepharon%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (11)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/33713555">A novel homozygous RIPK4 variant in a family with severe Bartsocas-Papas syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dinçer T,
Gümüş E,
Toraman B,
Er İ,
Yildiz G,
Yüksel Z,
Kalay E</span><br />
<span class="medgenPMjournal">Am J Med Genet A</span>
2021 Jun;185(6):1691-1699.
Epub 2021 Mar 13
doi: 10.1002/ajmg.a.62154.
<span class="bold">PMID: </span><a href="/pubmed/33713555" target="_blank">33713555</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27729131">Congenital oral synechia and ankyloblepharon filiforme adnatum: Case report and literature review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lima LB,
Barbosa de Paulo LF,
Silva CJ,
Mendes VC,
Simamoto-Júnior PC,
Durighetto AF</span><br />
<span class="medgenPMjournal">Int J Pediatr Otorhinolaryngol</span>
2016 Nov;90:196-199.
Epub 2016 Sep 20
doi: 10.1016/j.ijporl.2016.09.023.
<span class="bold">PMID: </span><a href="/pubmed/27729131" target="_blank">27729131</a></div>
<div class="nl"><a target="_blank" href="/pubmed/17185446">Ankyloblepharon filiforme adnatum.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Williams MA,
White ST,
McGinnity G</span><br />
<span class="medgenPMjournal">Arch Dis Child</span>
2007 Jan;92(1):73-4.
doi: 10.1136/adc.2006.103069.
<span class="bold">PMID: </span><a href="/pubmed/17185446" target="_blank">17185446</a><a href="/pmc/articles/PMC2083170" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/15807690">De novo missense mutation, S541Y, in the p63 gene underlying Rapp-Hodgkin ectodermal dysplasia syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shotelersuk V,
Janklat S,
Siriwan P,
Tongkobpetch S</span><br />
<span class="medgenPMjournal">Clin Exp Dermatol</span>
2005 May;30(3):282-5.
doi: 10.1111/j.1365-2230.2005.01722.x.
<span class="bold">PMID: </span><a href="/pubmed/15807690" target="_blank">15807690</a></div>
<div class="nl"><a target="_blank" href="/pubmed/14608644">Unreported manifestations in two Dutch families with Bartsocas-Papas syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Veenstra-Knol HE,
Kleibeuker A,
Timmer A,
ten Kate LP,
van Essen AJ</span><br />
<span class="medgenPMjournal">Am J Med Genet A</span>
2003 Dec 15;123A(3):243-8.
doi: 10.1002/ajmg.a.20308.
<span class="bold">PMID: </span><a href="/pubmed/14608644" target="_blank">14608644</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ankyloblepharon%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/29789014">A review of scoring systems for ocular involvement in chronic cutaneous bullous diseases.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lee BWH,
Tan JCK,
Radjenovic M,
Coroneo MT,
Murrell DF</span><br />
<span class="medgenPMjournal">Orphanet J Rare Dis</span>
2018 May 22;13(1):83.
doi: 10.1186/s13023-018-0823-5.
<span class="bold">PMID: </span><a href="/pubmed/29789014" target="_blank">29789014</a><a href="/pmc/articles/PMC5964694" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Koster MI,
Dinella J,
Chen J,
O'Shea C,
Koch PJ</span><br />
<span class="medgenPMjournal">Cell Commun Adhes</span>
2014 Feb;21(1):55-63.
doi: 10.3109/15419061.2013.876015.
<span class="bold">PMID: </span><a href="/pubmed/24460201" target="_blank">24460201</a><a href="/pmc/articles/PMC4117210" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/19681108">DeltaNp63 knockdown mice: A mouse model for AEC syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Koster MI,
Marinari B,
Payne AS,
Kantaputra PN,
Costanzo A,
Roop DR</span><br />
<span class="medgenPMjournal">Am J Med Genet A</span>
2009 Sep;149A(9):1942-7.
doi: 10.1002/ajmg.a.32794.
<span class="bold">PMID: </span><a href="/pubmed/19681108" target="_blank">19681108</a><a href="/pmc/articles/PMC2753548" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/18633439">IKKalpha is a p63 transcriptional target involved in the pathogenesis of ectodermal dysplasias.</a></div>
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Ballaro C,
Koster MI,
Giustizieri ML,
Moretti F,
Crosti F,
Papoutsaki M,
Karin M,
Alema S,
Chimenti S,
Roop DR,
Costanzo A</span><br />
<span class="medgenPMjournal">J Invest Dermatol</span>
2009 Jan;129(1):60-9.
Epub 2008 Jul 17
doi: 10.1038/jid.2008.202.
<span class="bold">PMID: </span><a href="/pubmed/18633439" target="_blank">18633439</a></div>
<div class="nl"><a target="_blank" href="/pubmed/15807690">De novo missense mutation, S541Y, in the p63 gene underlying Rapp-Hodgkin ectodermal dysplasia syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shotelersuk V,
Janklat S,
Siriwan P,
Tongkobpetch S</span><br />
<span class="medgenPMjournal">Clin Exp Dermatol</span>
2005 May;30(3):282-5.
doi: 10.1111/j.1365-2230.2005.01722.x.
<span class="bold">PMID: </span><a href="/pubmed/15807690" target="_blank">15807690</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ankyloblepharon%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (27)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/39074301">Clinical Characteristics of Ocular Mucous Membrane Pemphigoid: A Systematic Review and Meta-Analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bocanegra-Oyola N,
Pardo-Pizza D,
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Oliver-Hernández MV,
Romero-Osorio MJ,
Romero-Santos S,
Parra-Tanoux D,
Barragán AM,
de-la-Torre A</span><br />
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2024 Dec;32(10):2388-2404.
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<span class="bold">PMID: </span><a href="/pubmed/39074301" target="_blank">39074301</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30806540">A search for trachoma in Timor-Leste: no evidence to justify undertaking population-based prevalence surveys.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Correia M,
Brunner D,
Sharma M,
Andrade V,
Magno J,
Müller A,
Pereira BM,
Thumann G,
Verma N,
Bangert M,
Kreis AJ,
Solomon AW</span><br />
<span class="medgenPMjournal">Ophthalmic Epidemiol</span>
2018 Dec;25(sup1):131-137.
doi: 10.1080/09286586.2018.1545037.
<span class="bold">PMID: </span><a href="/pubmed/30806540" target="_blank">30806540</a><a href="/pmc/articles/PMC6858277" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ankyloblepharon%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2)</a></div></div>
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