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<meta name="keywords" content="C0266061, absence of overlap of upper and lower teeth, anatomical abnormality, apertognathia, bite, open, nonocclusion, open bite, open bite between upper and lower teeth, openbite, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Visible space between the dental arches in occlusion." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=78589
ConceptID=C0266061
-->
<!--imgCountBooks = 0--><div class="ncbi_carousel" data-ncbicarousel-config="imageWidth:'100px',numItemsVisible:2,toggler:false"><div class="nc_header"><span class="img_strip_title">Image</span></div><div class="nc_content"><div class="nc_item"><a class="figpopup"><img alt="Figure 1" src="/projects/medgen/images/thumb/10b2b6e5a7551847.1.thumb.jpg" src-large="/projects/medgen/images/10b2b6e5a7551847.1.jpg" /></a><br /><a href="http://elementsofmorphology.nih.gov/index.cgi?tid=10b2b6e5a7551847" target="_blank" title="Elements of Morphology: Human Malformation Terminology - NHGRI">details</a></div></div></div><h1 class="medgenTitle"><div class="MedGenTitleText">Open bite</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>78589</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0266061</a></dd><dt><span class="dotprefix"></span></dt><dd>Anatomical Abnormality</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Apertognathia; Bite, Open; Nonocclusion; Open Bite; Openbite</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Open bite (35580009)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0010807">HP:0010807</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Visible space between the dental arches in occlusion. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Open bite</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/6448" ref="tree=MeSH" title="MedGen record for Mouth disorder">Mouth disorder</a></span><ul><li><span class="TLline"><a href="/medgen/6448" ref="tree=MeSH" title="MedGen record for Mouth disorder">Mouth disorder</a></span><ul><li><span class="TLline"><a href="/medgen/312378" ref="tree=MeSH" title="MedGen record for Disorder of teeth AND/OR supporting structures">Disorder of teeth AND/OR supporting structures</a></span><ul><li><span class="TLline"><a href="/medgen/233769" ref="tree=MeSH" title="MedGen record for Non-Neoplastic Dental Disorder">Non-Neoplastic Dental Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/105412" ref="tree=MeSH" title="MedGen record for Disorder of tooth development">Disorder of tooth development</a></span><ul><li><span class="TLline"><a href="/medgen/9869" ref="tree=MeSH" title="MedGen record for Dental malocclusion">Dental malocclusion</a></span><ul><li><span class="matched_ds">Open bite</span><ul><li><span class="TLline"><a href="/medgen/120566" ref="tree=MeSH" title="MedGen record for Anterior open-bite malocclusion">Anterior open-bite malocclusion</a></span></li><li><span class="TLline"><a href="/medgen/346491" ref="tree=MeSH" title="MedGen record for Frontal open bite">Frontal open bite</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_266149"><div><strong>Cardio-facio-cutaneous syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>266149</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1275081</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Cardiofaciocutaneous (CFC) syndrome is characterized by cardiac abnormalities (pulmonic stenosis and other valve dysplasias, septal defects, hypertrophic cardiomyopathy, rhythm disturbances), distinctive craniofacial appearance, and cutaneous abnormalities (including xerosis, hyperkeratosis, ichthyosis, keratosis pilaris, ulerythema ophryogenes, eczema, pigmented moles, hemangiomas, and palmoplantar hyperkeratosis). The hair is typically sparse, curly, fine or thick, and woolly or brittle; eyelashes and eyebrows may be absent or sparse. Nails may be dystrophic or fast growing. Affected individuals typically have some form of neurologic and/or cognitive delay (ranging from mild to severe). Most individuals have severe feeding issues, which can contribute to poor growth, and many require nasogastric or gastrostomy tube feeding. Many affected individuals have eye findings, including strabismus, nystagmus, refractive errors, and optic nerve hypoplasia. Seizures may be present and can be refractory to therapy.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/266149">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_462274"><div><strong>Intellectual disability, anterior maxillary protrusion, and strabismus</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462274</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3150924</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">A rare genetic multiple congenital anomalies/dysmorphic syndrome with the association of severe intellectual disability, strabismus and anterior maxillary protrusion with vertical maxillary excess, open bite and prominent crowded teeth. Mild cochlear hearing loss has been reported in addition.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/462274">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1794274"><div><strong>Mucopolysaccharidosis, type 10</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1794274</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5562064</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Mucopolysaccharidosis type X (MPS10) is an autosomal recessive childhood-onset disorder associated with disproportionate short-trunk short stature and skeletal, cardiac, and ophthalmologic abnormalities (Verheyen et al., 2022).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1794274">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1824008"><div><strong>Neurodevelopmental disorder with craniofacial dysmorphism and skeletal defects</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1824008</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5774235</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Neurodevelopmental disorder with craniofacial dysmorphism and skeletal defects (NEDCDS) is characterized by global developmental delay, severely impaired intellectual development with poor or absent speech, characteristic facial features, and variable skeletal abnormalities. Additional features include feeding difficulties, inability to walk or walking with an abnormal gait, and cerebellar or other abnormalities on brain imaging (Reichert et al., 2020).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1824008">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_266149" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cardio-facio-cutaneous syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462274" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual disability, anterior maxillary protrusion, and strabismus</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1794274" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mucopolysaccharidosis, type 10</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1824008" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neurodevelopmental disorder with craniofacial dysmorphism and skeletal defects</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/37330726">Predictability of anterior open bite treatment with Invisalign.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blundell HL,
Weir T,
Byrne G</span><br />
<span class="medgenPMjournal">Am J Orthod Dentofacial Orthop</span>
2023 Nov;164(5):674-681.
Epub 2023 Jun 16
doi: 10.1016/j.ajodo.2023.04.017.
<span class="bold">PMID: </span><a href="/pubmed/37330726" target="_blank">37330726</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35034464">Open bite and atypical swallowing: orthodontic treatment, speech therapy or both? A literature review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Cenzato N,
Iannotti L,
Maspero C</span><br />
<span class="medgenPMjournal">Eur J Paediatr Dent</span>
2021 Dec;22(4):286-290.
doi: 10.23804/ejpd.2021.22.04.5.
<span class="bold">PMID: </span><a href="/pubmed/35034464" target="_blank">35034464</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23949448">Orthodontic treatment of anterior open bite: a review article--is surgery always necessary?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Reichert I,
Figel P,
Winchester L</span><br />
<span class="medgenPMjournal">Oral Maxillofac Surg</span>
2014 Sep;18(3):271-7.
Epub 2013 Aug 16
doi: 10.1007/s10006-013-0430-5.
<span class="bold">PMID: </span><a href="/pubmed/23949448" target="_blank">23949448</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22open%20bite%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (197)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37953383">Assessment of the efficacy of various maxillary molar intrusion therapies: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Abu Arqub S,
Al-Moghrabi D,
Iverson MG,
Farha P,
Alsalman HA,
Uribe F</span><br />
<span class="medgenPMjournal">Prog Orthod</span>
2023 Nov 13;24(1):37.
doi: 10.1186/s40510-023-00490-3.
<span class="bold">PMID: </span><a href="/pubmed/37953383" target="_blank">37953383</a><a href="/pmc/articles/PMC10641061" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35042361">Anterior open bite - diagnostics and therapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Michl P,
Broniš T,
Jurásková Sedlatá E,
Heinz P,
Pink R,
Šebek J,
Mottl R,
Dvořák Z,
Tvrdý P</span><br />
<span class="medgenPMjournal">Acta Chir Plast</span>
2021 Winter;63(4):181-184.
doi: 10.48095/ccachp2021181.
<span class="bold">PMID: </span><a href="/pubmed/35042361" target="_blank">35042361</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29532184">The effect of pacifier sucking on orofacial structures: a systematic literature review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Schmid KM,
Kugler R,
Nalabothu P,
Bosch C,
Verna C</span><br />
<span class="medgenPMjournal">Prog Orthod</span>
2018 Mar 13;19(1):8.
doi: 10.1186/s40510-018-0206-4.
<span class="bold">PMID: </span><a href="/pubmed/29532184" target="_blank">29532184</a><a href="/pmc/articles/PMC5847634" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27615261">Systematic review for orthodontic and orthopedic treatments for anterior open bite in the mixed dentition.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Pisani L,
Bonaccorso L,
Fastuca R,
Spena R,
Lombardo L,
Caprioglio A</span><br />
<span class="medgenPMjournal">Prog Orthod</span>
2016 Dec;17(1):28.
Epub 2016 Sep 19
doi: 10.1186/s40510-016-0142-0.
<span class="bold">PMID: </span><a href="/pubmed/27615261" target="_blank">27615261</a><a href="/pmc/articles/PMC5027197" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23338275">Open bite: diagnosis, treatment and stability.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Matsumoto MA,
Romano FL,
Ferreira JT,
Valério RA</span><br />
<span class="medgenPMjournal">Braz Dent J</span>
2012;23(6):768-78.
doi: 10.1590/s0103-64402012000600024.
<span class="bold">PMID: </span><a href="/pubmed/23338275" target="_blank">23338275</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Open%20bite%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1166)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/35042361">Anterior open bite - diagnostics and therapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Michl P,
Broniš T,
Jurásková Sedlatá E,
Heinz P,
Pink R,
Šebek J,
Mottl R,
Dvořák Z,
Tvrdý P</span><br />
<span class="medgenPMjournal">Acta Chir Plast</span>
2021 Winter;63(4):181-184.
doi: 10.48095/ccachp2021181.
<span class="bold">PMID: </span><a href="/pubmed/35042361" target="_blank">35042361</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23852257">Goldenhar syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sharma N,
Passi S</span><br />
<span class="medgenPMjournal">Indian J Dent Res</span>
2013 Jan-Feb;24(1):149.
doi: 10.4103/0970-9290.114952.
<span class="bold">PMID: </span><a href="/pubmed/23852257" target="_blank">23852257</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23338275">Open bite: diagnosis, treatment and stability.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Matsumoto MA,
Romano FL,
Ferreira JT,
Valério RA</span><br />
<span class="medgenPMjournal">Braz Dent J</span>
2012;23(6):768-78.
doi: 10.1590/s0103-64402012000600024.
<span class="bold">PMID: </span><a href="/pubmed/23338275" target="_blank">23338275</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23263437">Rabson-Mendenhall syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta J,
Daniel JM,
Vasudevan V</span><br />
<span class="medgenPMjournal">J Indian Soc Pedod Prev Dent</span>
2012 Jul-Sep;30(3):279-82.
doi: 10.4103/0970-4388.105026.
<span class="bold">PMID: </span><a href="/pubmed/23263437" target="_blank">23263437</a></div>
<div class="nl"><a target="_blank" href="/pubmed/20038906">Cri du chat syndrome: a critical review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rodríguez-Caballero A,
Torres-Lagares D,
Rodríguez-Pérez A,
Serrera-Figallo MA,
Hernández-Guisado JM,
Machuca-Portillo G</span><br />
<span class="medgenPMjournal">Med Oral Patol Oral Cir Bucal</span>
2010 May 1;15(3):e473-8.
doi: 10.4317/medoral.15.e473.
<span class="bold">PMID: </span><a href="/pubmed/20038906" target="_blank">20038906</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Open%20bite%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (542)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/37953383">Assessment of the efficacy of various maxillary molar intrusion therapies: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Abu Arqub S,
Al-Moghrabi D,
Iverson MG,
Farha P,
Alsalman HA,
Uribe F</span><br />
<span class="medgenPMjournal">Prog Orthod</span>
2023 Nov 13;24(1):37.
doi: 10.1186/s40510-023-00490-3.
<span class="bold">PMID: </span><a href="/pubmed/37953383" target="_blank">37953383</a><a href="/pmc/articles/PMC10641061" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35742703">Prevalence of Orthodontic Malocclusions in Healthy Children and Adolescents: A Systematic Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">De Ridder L,
Aleksieva A,
Willems G,
Declerck D,
Cadenas de Llano-Pérula M</span><br />
<span class="medgenPMjournal">Int J Environ Res Public Health</span>
2022 Jun 17;19(12)
doi: 10.3390/ijerph19127446.
<span class="bold">PMID: </span><a href="/pubmed/35742703" target="_blank">35742703</a><a href="/pmc/articles/PMC9223594" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29532184">The effect of pacifier sucking on orofacial structures: a systematic literature review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Schmid KM,
Kugler R,
Nalabothu P,
Bosch C,
Verna C</span><br />
<span class="medgenPMjournal">Prog Orthod</span>
2018 Mar 13;19(1):8.
doi: 10.1186/s40510-018-0206-4.
<span class="bold">PMID: </span><a href="/pubmed/29532184" target="_blank">29532184</a><a href="/pmc/articles/PMC5847634" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27615261">Systematic review for orthodontic and orthopedic treatments for anterior open bite in the mixed dentition.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Pisani L,
Bonaccorso L,
Fastuca R,
Spena R,
Lombardo L,
Caprioglio A</span><br />
<span class="medgenPMjournal">Prog Orthod</span>
2016 Dec;17(1):28.
Epub 2016 Sep 19
doi: 10.1186/s40510-016-0142-0.
<span class="bold">PMID: </span><a href="/pubmed/27615261" target="_blank">27615261</a><a href="/pmc/articles/PMC5027197" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25267151">Atypical swallowing: a review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Maspero C,
Prevedello C,
Giannini L,
Galbiati G,
Farronato G</span><br />
<span class="medgenPMjournal">Minerva Stomatol</span>
2014 Jun;63(6):217-27.
<span class="bold">PMID: </span><a href="/pubmed/25267151" target="_blank">25267151</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Open%20bite%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (426)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37330726">Predictability of anterior open bite treatment with Invisalign.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blundell HL,
Weir T,
Byrne G</span><br />
<span class="medgenPMjournal">Am J Orthod Dentofacial Orthop</span>
2023 Nov;164(5):674-681.
Epub 2023 Jun 16
doi: 10.1016/j.ajodo.2023.04.017.
<span class="bold">PMID: </span><a href="/pubmed/37330726" target="_blank">37330726</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35042361">Anterior open bite - diagnostics and therapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Michl P,
Broniš T,
Jurásková Sedlatá E,
Heinz P,
Pink R,
Šebek J,
Mottl R,
Dvořák Z,
Tvrdý P</span><br />
<span class="medgenPMjournal">Acta Chir Plast</span>
2021 Winter;63(4):181-184.
doi: 10.48095/ccachp2021181.
<span class="bold">PMID: </span><a href="/pubmed/35042361" target="_blank">35042361</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25376143">Bilateral condylar resorption in down syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Grippaudo C,
Grippaudo FR,
Marianetti TM,
Cacucci L,
Deli R,
Pelo S</span><br />
<span class="medgenPMjournal">J Craniofac Surg</span>
2014 Nov;25(6):e580-2.
doi: 10.1097/SCS.0000000000001019.
<span class="bold">PMID: </span><a href="/pubmed/25376143" target="_blank">25376143</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23338275">Open bite: diagnosis, treatment and stability.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Matsumoto MA,
Romano FL,
Ferreira JT,
Valério RA</span><br />
<span class="medgenPMjournal">Braz Dent J</span>
2012;23(6):768-78.
doi: 10.1590/s0103-64402012000600024.
<span class="bold">PMID: </span><a href="/pubmed/23338275" target="_blank">23338275</a></div>
<div class="nl"><a target="_blank" href="/pubmed/5280426">Open-bite.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Worms FW,
Meskin LH,
Isaacson RJ</span><br />
<span class="medgenPMjournal">Am J Orthod</span>
1971 Jun;59(6):589-95.
doi: 10.1016/0002-9416(71)90005-4.
<span class="bold">PMID: </span><a href="/pubmed/5280426" target="_blank">5280426</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Open%20bite%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (542)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37953383">Assessment of the efficacy of various maxillary molar intrusion therapies: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Abu Arqub S,
Al-Moghrabi D,
Iverson MG,
Farha P,
Alsalman HA,
Uribe F</span><br />
<span class="medgenPMjournal">Prog Orthod</span>
2023 Nov 13;24(1):37.
doi: 10.1186/s40510-023-00490-3.
<span class="bold">PMID: </span><a href="/pubmed/37953383" target="_blank">37953383</a><a href="/pmc/articles/PMC10641061" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37330726">Predictability of anterior open bite treatment with Invisalign.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blundell HL,
Weir T,
Byrne G</span><br />
<span class="medgenPMjournal">Am J Orthod Dentofacial Orthop</span>
2023 Nov;164(5):674-681.
Epub 2023 Jun 16
doi: 10.1016/j.ajodo.2023.04.017.
<span class="bold">PMID: </span><a href="/pubmed/37330726" target="_blank">37330726</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33223374">Class II malocclusion correction with Invisalign: Is it possible?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Patterson BD,
Foley PF,
Ueno H,
Mason SA,
Schneider PP,
Kim KB</span><br />
<span class="medgenPMjournal">Am J Orthod Dentofacial Orthop</span>
2021 Jan;159(1):e41-e48.
Epub 2020 Nov 19
doi: 10.1016/j.ajodo.2020.08.016.
<span class="bold">PMID: </span><a href="/pubmed/33223374" target="_blank">33223374</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32830306">Evaluation of open bite closure using clear aligners: a retrospective study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Harris K,
Ojima K,
Dan C,
Upadhyay M,
Alshehri A,
Kuo CL,
Mu J,
Uribe F,
Nanda R</span><br />
<span class="medgenPMjournal">Prog Orthod</span>
2020 Aug 24;21(1):23.
doi: 10.1186/s40510-020-00325-5.
<span class="bold">PMID: </span><a href="/pubmed/32830306" target="_blank">32830306</a><a href="/pmc/articles/PMC7443419" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30672991">Global distribution of malocclusion traits: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Alhammadi MS,
Halboub E,
Fayed MS,
Labib A,
El-Saaidi C</span><br />
<span class="medgenPMjournal">Dental Press J Orthod</span>
2018 Nov-Dec;23(6):40.e1-40.e10.
doi: 10.1590/2177-6709.23.6.40.e1-10.onl.
<span class="bold">PMID: </span><a href="/pubmed/30672991" target="_blank">30672991</a><a href="/pmc/articles/PMC6340198" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Open%20bite%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (572)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/35742703">Prevalence of Orthodontic Malocclusions in Healthy Children and Adolescents: A Systematic Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">De Ridder L,
Aleksieva A,
Willems G,
Declerck D,
Cadenas de Llano-Pérula M</span><br />
<span class="medgenPMjournal">Int J Environ Res Public Health</span>
2022 Jun 17;19(12)
doi: 10.3390/ijerph19127446.
<span class="bold">PMID: </span><a href="/pubmed/35742703" target="_blank">35742703</a><a href="/pmc/articles/PMC9223594" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35034464">Open bite and atypical swallowing: orthodontic treatment, speech therapy or both? A literature review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Cenzato N,
Iannotti L,
Maspero C</span><br />
<span class="medgenPMjournal">Eur J Paediatr Dent</span>
2021 Dec;22(4):286-290.
doi: 10.23804/ejpd.2021.22.04.5.
<span class="bold">PMID: </span><a href="/pubmed/35034464" target="_blank">35034464</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32888097">Stability of anterior open bite treatment with molar intrusion using skeletal anchorage: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">González Espinosa D,
de Oliveira Moreira PE,
da Sousa AS,
Flores-Mir C,
Normando D</span><br />
<span class="medgenPMjournal">Prog Orthod</span>
2020 Sep 5;21(1):35.
doi: 10.1186/s40510-020-00328-2.
<span class="bold">PMID: </span><a href="/pubmed/32888097" target="_blank">32888097</a><a href="/pmc/articles/PMC7474024" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30672991">Global distribution of malocclusion traits: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Alhammadi MS,
Halboub E,
Fayed MS,
Labib A,
El-Saaidi C</span><br />
<span class="medgenPMjournal">Dental Press J Orthod</span>
2018 Nov-Dec;23(6):40.e1-40.e10.
doi: 10.1590/2177-6709.23.6.40.e1-10.onl.
<span class="bold">PMID: </span><a href="/pubmed/30672991" target="_blank">30672991</a><a href="/pmc/articles/PMC6340198" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27615261">Systematic review for orthodontic and orthopedic treatments for anterior open bite in the mixed dentition.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Pisani L,
Bonaccorso L,
Fastuca R,
Spena R,
Lombardo L,
Caprioglio A</span><br />
<span class="medgenPMjournal">Prog Orthod</span>
2016 Dec;17(1):28.
Epub 2016 Sep 19
doi: 10.1186/s40510-016-0142-0.
<span class="bold">PMID: </span><a href="/pubmed/27615261" target="_blank">27615261</a><a href="/pmc/articles/PMC5027197" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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