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<meta name="keywords" content="C0518656, chronic extreme exhaustion, chronic fatigue, finding, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Subjective feeling of tiredness characterized by a lack of energy and motivation that persists for six months or longer." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=760077
|
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ConceptID=C0518656
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Chronic fatigue</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>760077</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0518656</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Chronic extreme exhaustion</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0012432">HP:0012432</a></td></tr>
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||
<div class="portlet_content ln">Subjective feeling of tiredness characterized by a lack of energy and motivation that persists for six months or longer. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Chronic fatigue</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/19974" ref="tree=MeSH" title="MedGen record for Clinical finding">Clinical finding</a></span><ul><li><span class="TLline"><a href="/medgen/41971" ref="tree=MeSH" title="MedGen record for Fatigue">Fatigue</a></span><ul><li><span class="matched_ds">Chronic fatigue</span></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
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<div class="portlet mgSection" id="ID_112">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_120634"><div><strong>Familial amyloid nephropathy with urticaria AND deafness</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>120634</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268390</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Muckle-Wells syndrome (MWS) is characterized by episodic skin rash, arthralgias, and fever associated with late-onset sensorineural deafness and renal amyloidosis (Dode et al., 2002).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/120634">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_90956"><div><strong>Familial pulmonary capillary hemangiomatosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>90956</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0340848</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pulmonary venoocclusive disease-2 is an autosomal recessive subtype of primary pulmonary hypertension (PPH; see 178600). It is characterized histologically by widespread fibrous intimal proliferation of septal veins and preseptal venules, and is frequently associated with pulmonary capillary dilatation and proliferation. The disorder can cause occult alveolar hemorrhage. High-resolution CT imaging of the chest shows patchy centrilobular ground-glass opacities, septal lines, and lymph node enlargement (summary by Eyries et al., 2014). For a discussion of genetic heterogeneity of pulmonary venoocclusive disease, see PVOD1 (265450).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/90956">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_350479"><div><strong>Gaucher disease due to saposin C deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>350479</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1864651</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Any Gaucher disease in which the cause of the disease is a mutation in the PSAP gene.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/350479">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_462437"><div><strong>Aneurysm-osteoarthritis syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462437</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3151087</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, and cervical spine malformation and/or instability), craniofacial features (hypertelorism, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/462437">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1646567"><div><strong>Loeys-Dietz syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1646567</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551955</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, and cervical spine malformation and/or instability), craniofacial features (hypertelorism, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1646567">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1632001"><div><strong>Ehlers-Danlos syndrome, classic-like, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1632001</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4693870</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Ehlers-Danlos syndrome classic-like-2 (EDSCLL2) is characterized by severe joint and skin laxity, osteoporosis involving the hips and spine, osteoarthritis, soft redundant skin that can be acrogeria-like, delayed wound healing with abnormal atrophic scarring, and shoulder, hip, knee, and ankle dislocations. Variable features include gastrointestinal and genitourinary manifestations, such as bowel rupture, gut dysmotility, cryptorchidism, and hernias; vascular complications, such as mitral valve prolapse and aortic root dilation; and skeletal anomalies (Blackburn et al., 2018). For a discussion of genetic heterogeneity of classic-like Ehlers-Danlos syndrome, see 606408. For a discussion of the classification of EDS, see 130000.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1632001">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1717739"><div><strong>Bone marrow failure syndrome 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1717739</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5394274</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Bone marrow failure syndrome-6 (BMFS6) is an autosomal dominant disorder characterized by variable features of hypocellular bone marrow, anemia, neutropenia, lymphopenia, and increased incidence of cancer (Toufektchan et al., 2020). For a discussion of genetic heterogeneity of BMFS, see BMFS1 (614675).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1717739">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1740270"><div><strong>Immunodeficiency 70</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1740270</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5436501</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Immunodeficiency-70 (IMD70) is an autosomal dominant immunologic disorder characterized by severe cutaneous warts on the hands, feet, and face, suggesting increased susceptibility to human papillomavirus (HPV) infection. Affected individuals may also have recurrent bacterial infections, such as sinusitis, as well as feature of autoinflammation, such as colitis, celiac disease, and retinal vasculitis. Laboratory studies show decreased CD4+ T cells and decreased CD19+ B cells; hypogammaglobulinemia has also been observed (summary by Thaventhiran et al., 2020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1740270">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1794251"><div><strong>Loeys-Dietz syndrome 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1794251</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5562041</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, and cervical spine malformation and/or instability), craniofacial features (hypertelorism, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1794251">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462437" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Aneurysm-osteoarthritis syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1717739" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Bone marrow failure syndrome 6</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1632001" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ehlers-Danlos syndrome, classic-like, 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_120634" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial amyloid nephropathy with urticaria AND deafness</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_90956" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial pulmonary capillary hemangiomatosis</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (9)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_350479" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Gaucher disease due to saposin C deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1740270" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency 70</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1646567" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Loeys-Dietz syndrome 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1794251" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Loeys-Dietz syndrome 6</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37793728">Diagnosis and Management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Grach SL,
|
||
Seltzer J,
|
||
Chon TY,
|
||
Ganesh R</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
2023 Oct;98(10):1544-1551.
|
||
doi: 10.1016/j.mayocp.2023.07.032.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37793728" target="_blank">37793728</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34454716">Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Essentials of Diagnosis and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bateman L,
|
||
Bested AC,
|
||
Bonilla HF,
|
||
Chheda BV,
|
||
Chu L,
|
||
Curtin JM,
|
||
Dempsey TT,
|
||
Dimmock ME,
|
||
Dowell TG,
|
||
Felsenstein D,
|
||
Kaufman DL,
|
||
Klimas NG,
|
||
Komaroff AL,
|
||
Lapp CW,
|
||
Levine SM,
|
||
Montoya JG,
|
||
Natelson BH,
|
||
Peterson DL,
|
||
Podell RN,
|
||
Rey IR,
|
||
Ruhoy IS,
|
||
Vera-Nunez MA,
|
||
Yellman BP</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
2021 Nov;96(11):2861-2878.
|
||
Epub 2021 Aug 25
|
||
doi: 10.1016/j.mayocp.2021.07.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34454716" target="_blank">34454716</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33246515">Approach to Fatigue: Best Practice.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dukes JC,
|
||
Chakan M,
|
||
Mills A,
|
||
Marcaurd M</span><br />
|
||
<span class="medgenPMjournal">Med Clin North Am</span>
|
||
2021 Jan;105(1):137-148.
|
||
doi: 10.1016/j.mcna.2020.09.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33246515" target="_blank">33246515</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22chronic%20fatigue%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (382)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38386732">Chronic fatigue study shows syndrome's complexity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Couzin-Frankel J</span><br />
|
||
<span class="medgenPMjournal">Science</span>
|
||
2024 Feb 23;383(6685):804-805.
|
||
Epub 2024 Feb 22
|
||
doi: 10.1126/science.ado7759.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38386732" target="_blank">38386732</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37526404">A multicenter virome analysis of blood, feces, and saliva in myalgic encephalomyelitis/chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Briese T,
|
||
Tokarz R,
|
||
Bateman L,
|
||
Che X,
|
||
Guo C,
|
||
Jain K,
|
||
Kapoor V,
|
||
Levine S,
|
||
Hornig M,
|
||
Oleynik A,
|
||
Quan PL,
|
||
Wong WH,
|
||
Williams BL,
|
||
Vernon SD,
|
||
Klimas NG,
|
||
Peterson DL,
|
||
Montoya JG,
|
||
Ian Lipkin W</span><br />
|
||
<span class="medgenPMjournal">J Med Virol</span>
|
||
2023 Aug;95(8):e28993.
|
||
doi: 10.1002/jmv.28993.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37526404" target="_blank">37526404</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26415100">Chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cleare AJ,
|
||
Reid S,
|
||
Chalder T,
|
||
Hotopf M,
|
||
Wessely S</span><br />
|
||
<span class="medgenPMjournal">BMJ Clin Evid</span>
|
||
2015 Sep 28;2015
|
||
<span class="bold">PMID: </span><a href="/pubmed/26415100" target="_blank">26415100</a><a href="/pmc/articles/PMC4585442" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23101300">Chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tracy M</span><br />
|
||
<span class="medgenPMjournal">Nurs Stand</span>
|
||
2012 Sep 26-Oct 2;27(4):57.
|
||
doi: 10.7748/ns2012.09.27.4.57.c9315.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23101300" target="_blank">23101300</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9436061">Chronic fatigue syndrome in children and adolescents: a review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jordan KM,
|
||
Landis DA,
|
||
Downey MC,
|
||
Osterman SL,
|
||
Thurm AE,
|
||
Jason LA</span><br />
|
||
<span class="medgenPMjournal">J Adolesc Health</span>
|
||
1998 Jan;22(1):4-18.
|
||
doi: 10.1016/S1054-139X(97)00212-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9436061" target="_blank">9436061</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20fatigue%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3143)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37793728">Diagnosis and Management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Grach SL,
|
||
Seltzer J,
|
||
Chon TY,
|
||
Ganesh R</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
2023 Oct;98(10):1544-1551.
|
||
doi: 10.1016/j.mayocp.2023.07.032.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37793728" target="_blank">37793728</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33559123">Young and exhausted.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Oleksak F,
|
||
Durdik P,
|
||
Jakusova L,
|
||
Turcan T,
|
||
Banovcin P</span><br />
|
||
<span class="medgenPMjournal">Adv Respir Med</span>
|
||
2021;89(1):92-95.
|
||
Epub 2021 Feb 9
|
||
doi: 10.5603/ARM.a2020.0196.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33559123" target="_blank">33559123</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33328173">Updated NICE guidance on chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Turner-Stokes L,
|
||
Wade DT</span><br />
|
||
<span class="medgenPMjournal">BMJ</span>
|
||
2020 Dec 16;371:m4774.
|
||
doi: 10.1136/bmj.m4774.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33328173" target="_blank">33328173</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23062157">Chronic fatigue syndrome: diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yancey JR,
|
||
Thomas SM</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2012 Oct 15;86(8):741-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23062157" target="_blank">23062157</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7747645">Chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McKenzie R,
|
||
Straus SE</span><br />
|
||
<span class="medgenPMjournal">Adv Intern Med</span>
|
||
1995;40:119-53.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7747645" target="_blank">7747645</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20fatigue%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3240)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28730271">Serious adverse events after HPV vaccination: a critical review of randomized trials and post-marketing case series.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Martínez-Lavín M,
|
||
Amezcua-Guerra L</span><br />
|
||
<span class="medgenPMjournal">Clin Rheumatol</span>
|
||
2017 Oct;36(10):2169-2178.
|
||
Epub 2017 Jul 20
|
||
doi: 10.1007/s10067-017-3768-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28730271" target="_blank">28730271</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28444695">Exercise therapy for chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Larun L,
|
||
Brurberg KG,
|
||
Odgaard-Jensen J,
|
||
Price JR</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2017 Apr 25;4(4):CD003200.
|
||
doi: 10.1002/14651858.CD003200.pub7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28444695" target="_blank">28444695</a><a href="/pmc/articles/PMC6419524" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26883460">Autoantibody pain.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Goebel A</span><br />
|
||
<span class="medgenPMjournal">Autoimmun Rev</span>
|
||
2016 Jun;15(6):552-7.
|
||
Epub 2016 Feb 12
|
||
doi: 10.1016/j.autrev.2016.02.011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26883460" target="_blank">26883460</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12094819">Focus on amisulpride.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Green B</span><br />
|
||
<span class="medgenPMjournal">Curr Med Res Opin</span>
|
||
2002;18(3):113-7.
|
||
doi: 10.1185/030079902125000363.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12094819" target="_blank">12094819</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7747645">Chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McKenzie R,
|
||
Straus SE</span><br />
|
||
<span class="medgenPMjournal">Adv Intern Med</span>
|
||
1995;40:119-53.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7747645" target="_blank">7747645</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20fatigue%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1726)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/29908859">Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493 737 UK Biobank participants.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hanlon P,
|
||
Nicholl BI,
|
||
Jani BD,
|
||
Lee D,
|
||
McQueenie R,
|
||
Mair FS</span><br />
|
||
<span class="medgenPMjournal">Lancet Public Health</span>
|
||
2018 Jul;3(7):e323-e332.
|
||
Epub 2018 Jun 14
|
||
doi: 10.1016/S2468-2667(18)30091-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29908859" target="_blank">29908859</a><a href="/pmc/articles/PMC6028743" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28228103">Disease manifestations and burden of illness in patients with acid sphingomyelinase deficiency (ASMD).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McGovern MM,
|
||
Avetisyan R,
|
||
Sanson BJ,
|
||
Lidove O</span><br />
|
||
<span class="medgenPMjournal">Orphanet J Rare Dis</span>
|
||
2017 Feb 23;12(1):41.
|
||
doi: 10.1186/s13023-017-0572-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28228103" target="_blank">28228103</a><a href="/pmc/articles/PMC5322625" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23101300">Chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tracy M</span><br />
|
||
<span class="medgenPMjournal">Nurs Stand</span>
|
||
2012 Sep 26-Oct 2;27(4):57.
|
||
doi: 10.7748/ns2012.09.27.4.57.c9315.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23101300" target="_blank">23101300</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9174726">Chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Demitrack MA,
|
||
Engleberg NC</span><br />
|
||
<span class="medgenPMjournal">Curr Ther Endocrinol Metab</span>
|
||
1997;6:152-60.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9174726" target="_blank">9174726</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8521932">The epidemiology of chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wessely S</span><br />
|
||
<span class="medgenPMjournal">Epidemiol Rev</span>
|
||
1995;17(1):139-51.
|
||
doi: 10.1093/oxfordjournals.epirev.a036170.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8521932" target="_blank">8521932</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20fatigue%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1219)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38331137">Clinical and Laboratory Characteristics of Fatigue-Dominant Long-COVID Subjects: A Cross-Sectional Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee JS,
|
||
Choi Y,
|
||
Joung JY,
|
||
Son CG</span><br />
|
||
<span class="medgenPMjournal">Am J Med</span>
|
||
2025 Feb;138(2):346-353.e1.
|
||
Epub 2024 Feb 6
|
||
doi: 10.1016/j.amjmed.2024.01.025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38331137" target="_blank">38331137</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28805514">Investigator bias and the PACE trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lubet S</span><br />
|
||
<span class="medgenPMjournal">J Health Psychol</span>
|
||
2017 Aug;22(9):1123-1127.
|
||
Epub 2017 Mar 7
|
||
doi: 10.1177/1359105317697324.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28805514" target="_blank">28805514</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28444695">Exercise therapy for chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Larun L,
|
||
Brurberg KG,
|
||
Odgaard-Jensen J,
|
||
Price JR</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2017 Apr 25;4(4):CD003200.
|
||
doi: 10.1002/14651858.CD003200.pub7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28444695" target="_blank">28444695</a><a href="/pmc/articles/PMC6419524" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25583468">Nonceliac gluten sensitivity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fasano A,
|
||
Sapone A,
|
||
Zevallos V,
|
||
Schuppan D</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2015 May;148(6):1195-204.
|
||
Epub 2015 Jan 9
|
||
doi: 10.1053/j.gastro.2014.12.049.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25583468" target="_blank">25583468</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12093668">Evidence for the presence of immune dysfunction in chronic fatigue syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Natelson BH,
|
||
Haghighi MH,
|
||
Ponzio NM</span><br />
|
||
<span class="medgenPMjournal">Clin Diagn Lab Immunol</span>
|
||
2002 Jul;9(4):747-52.
|
||
doi: 10.1128/cdli.9.4.747-752.2002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12093668" target="_blank">12093668</a><a href="/pmc/articles/PMC120010" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20fatigue%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2084)</a></div></div>
|
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|
||
|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
|
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<div class="nl"><a target="_blank" href="/pubmed/36901108">Effectiveness of Pain Neuroscience Education in Patients with Chronic Musculoskeletal Pain and Central Sensitization: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lepri B,
|
||
Romani D,
|
||
Storari L,
|
||
Barbari V</span><br />
|
||
<span class="medgenPMjournal">Int J Environ Res Public Health</span>
|
||
2023 Feb 24;20(5)
|
||
doi: 10.3390/ijerph20054098.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36901108" target="_blank">36901108</a><a href="/pmc/articles/PMC10001851" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34445021">Plant Adaptogens-History and Future Perspectives.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Todorova V,
|
||
Ivanov K,
|
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Delattre C,
|
||
Nalbantova V,
|
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Karcheva-Bahchevanska D,
|
||
Ivanova S</span><br />
|
||
<span class="medgenPMjournal">Nutrients</span>
|
||
2021 Aug 20;13(8)
|
||
doi: 10.3390/nu13082861.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34445021" target="_blank">34445021</a><a href="/pmc/articles/PMC8398443" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31906979">Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kim DY,
|
||
Lee JS,
|
||
Park SY,
|
||
Kim SJ,
|
||
Son CG</span><br />
|
||
<span class="medgenPMjournal">J Transl Med</span>
|
||
2020 Jan 6;18(1):7.
|
||
doi: 10.1186/s12967-019-02196-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31906979" target="_blank">31906979</a><a href="/pmc/articles/PMC6943902" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29624410">Ginseng as a Treatment for Fatigue: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Arring NM,
|
||
Millstine D,
|
||
Marks LA,
|
||
Nail LM</span><br />
|
||
<span class="medgenPMjournal">J Altern Complement Med</span>
|
||
2018 Jul;24(7):624-633.
|
||
Epub 2018 Apr 6
|
||
doi: 10.1089/acm.2017.0361.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29624410" target="_blank">29624410</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27557747">Adrenal fatigue does not exist: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cadegiani FA,
|
||
Kater CE</span><br />
|
||
<span class="medgenPMjournal">BMC Endocr Disord</span>
|
||
2016 Aug 24;16(1):48.
|
||
doi: 10.1186/s12902-016-0128-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27557747" target="_blank">27557747</a><a href="/pmc/articles/PMC4997656" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20fatigue%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (209)</a></div></div>
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22chronic%20fatigue%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Chronic%20fatigue%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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