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<meta name="keywords" content="C0025222, altered blood in stool, altered blood passed per rectum, black faeces, black feces, black, tarry stool, melaena, melena, melenas, pathologic function, tarry stools, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="The passage of blackish, tarry feces associated with gastrointestinal hemorrhage. Melena occurs if the blood remains in the colon long enough for it to be broken down by colonic bacteria. One degradation product, hematin, imbues the stool with a blackish color. Thus, melena generally occurs with bleeding from the upper gastrointestinal tract (e.g., stomach ulcers or duodenal ulcers), since the blood usually remains in the gut for a longer period of time than with lower gastrointestinal bleeding." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=7523
|
||
ConceptID=C0025222
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Melena</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>7523</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0025222</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Pathologic Function</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Melenas</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Altered blood passed per rectum (2901004); Altered blood in stool (2901004); Black, tarry stool (2901004); Melena (2901004); Tarry stools (2901004)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0002249">HP:0002249</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">The passage of blackish, tarry feces associated with gastrointestinal hemorrhage. Melena occurs if the blood remains in the colon long enough for it to be broken down by colonic bacteria. One degradation product, hematin, imbues the stool with a blackish color. Thus, melena generally occurs with bleeding from the upper gastrointestinal tract (e.g., stomach ulcers or duodenal ulcers), since the blood usually remains in the gut for a longer period of time than with lower gastrointestinal bleeding. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Melena</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/3828" ref="tree=MeSH" title="MedGen record for Disorder of digestive system">Disorder of digestive system</a></span><ul><li><span class="TLline"><a href="/medgen/78584" ref="tree=MeSH" title="MedGen record for Abnormality of the digestive system">Abnormality of the digestive system</a></span><ul><li><span class="TLline"><a href="/medgen/927601" ref="tree=MeSH" title="MedGen record for Abnormality of digestive system physiology">Abnormality of digestive system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/488929" ref="tree=MeSH" title="MedGen record for Abdominal symptom">Abdominal symptom</a></span><ul><li><span class="TLline"><a href="/medgen/8360" ref="tree=MeSH" title="MedGen record for Diarrhea">Diarrhea</a></span><ul><li><span class="TLline"><a href="/medgen/56232" ref="tree=MeSH" title="MedGen record for Bloody diarrhea">Bloody diarrhea</a></span><ul><li><span class="matched_ds">Melena</span><ul><li><span class="TLline"><a href="/medgen/634842" ref="tree=MeSH" title="MedGen record for Neonatal melena">Neonatal melena</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
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<div class="portlet mgSection" id="ID_112">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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||
<div class="divPopper rprt" id="rdis_945"><div><strong>Hereditary factor IX deficiency disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>945</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0008533</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hemophilia B is characterized by deficiency in factor IX clotting activity that results in prolonged oozing after injuries, tooth extractions, or surgery, and delayed or recurrent bleeding prior to complete wound healing. The age of diagnosis and frequency of bleeding episodes are related to the level of factor IX clotting activity. In any individual with hemophilia B, bleeding episodes may be more frequent in childhood and adolescence than in adulthood. Individuals with severe hemophilia B are usually diagnosed during the first two years of life. Without prophylactic treatment, they may average up to two to five spontaneous bleeding episodes each month, including spontaneous joint or muscle bleeds, and prolonged bleeding or excessive pain and swelling from minor injuries, surgery, and tooth extractions. Individuals with moderate hemophilia B seldom have spontaneous bleeding, although it varies between individuals; however, they do have prolonged or delayed oozing after relatively minor trauma and are usually diagnosed before age five to six years. The frequency of bleeding episodes varies from once a month to once a year. Individuals with mild hemophilia B do not have spontaneous bleeding episodes; however, without pre- and postoperative treatment, abnormal bleeding occurs with surgery or tooth extractions. The frequency of bleeding may vary from once a year to once every ten years. Individuals with mild hemophilia B are often not diagnosed until later in life. Approximately 30% of heterozygous females have factor IX clotting activity lower than 40% and are at risk for bleeding (even if the affected family member has mild hemophilia B). As in males, bleeding severity generally correlates with factor levels. After major trauma or invasive procedures, prolonged or excessive bleeding usually occurs, regardless of severity.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/945">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_5501"><div><strong>Hereditary factor VIII deficiency disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5501</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0019069</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hemophilia A is characterized by deficiency in factor VIII clotting activity that results in prolonged bleeding after injuries, tooth extractions, or surgery, and delayed or recurrent bleeding prior to complete wound healing. The age of diagnosis and frequency of bleeding episodes are related to the level of factor VIII clotting activity. Individuals with severe hemophilia A are usually diagnosed during the first two years of life following oral or soft tissue bleeding either with procedures or due to a known family history of hemophilia. Without prophylactic treatment, individuals may average up to two to five spontaneous bleeding episodes each month including spontaneous joint bleeds or deep-muscle hematomas, and prolonged bleeding or excessive pain and swelling from minor injuries, surgery, and tooth extractions. Individuals with moderate hemophilia A seldom have spontaneous bleeding, although it varies between individuals; however, they do have prolonged or delayed bleeding after relatively minor trauma and are usually diagnosed before age five to six years; the frequency of bleeding episodes varies, usually from once a month to once a year. Individuals with mild hemophilia A do not have spontaneous bleeding episodes; however, without pre- and postoperative treatment, abnormal bleeding occurs with surgery or tooth extractions; the frequency of bleeding episodes varies widely, typically from once a year to once every ten years. Individuals with mild hemophilia A are often not diagnosed until later in life. Approximately 30% of heterozygous females have factor VIII clotting activity below 40% and are at risk for bleeding (even if males in the family are only mildly affected). After major trauma or invasive procedures, prolonged or excessive bleeding usually occurs, regardless of severity. In addition, 25% of heterozygous females with normal factor VIII clotting activity report an increased bleeding tendency.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5501">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_21921"><div><strong>Wiskott-Aldrich syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>21921</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0043194</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The WAS-related disorders, which include Wiskott-Aldrich syndrome, X-linked thrombocytopenia (XLT), and X-linked neutropenia (XLN), are a spectrum of disorders of hematopoietic cells, with predominant defects of platelets and lymphocytes. Wiskott-Aldrich syndrome usually presents in infancy. Affected males have thrombocytopenia with intermittent mucosal bleeding, bloody diarrhea, and intermittent or chronic petechiae and purpura; recurrent bacterial, viral, fungal, and/or opportunistic infections; and eczema. Approximately 25%-40% of those who survive the early complications develop one or more autoimmune conditions including hemolytic anemia, immune thrombocytopenic purpura, immune-mediated neutropenia, vasculitis, rheumatoid arthritis, and immune-mediated damage to the kidneys and liver. Individuals with a WAS-related disorder, particularly those who have been exposed to Epstein-Barr virus (EBV), are at increased risk of developing lymphomas, which often occur in unusual extranodal locations including the brain, lung, or gastrointestinal tract. Males with XLT have small platelet volume and thrombocytopenia. Severe disease-related events include severe bleeding episodes (14%), autoimmunity (12%), life-threatening infections (7%), and malignancy (5%). Males with XLN typically have congenital neutropenia associated with myelodysplasia, hyperactive neutrophils, increased myeloid cell apoptosis, and lymphoid cell abnormalities.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/21921">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_75688"><div><strong>Tyrosinemia type I</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>75688</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268490</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Untreated tyrosinemia type I usually presents either in young infants with severe liver involvement or later in the first year with liver dysfunction and renal tubular dysfunction associated with growth failure and rickets. Untreated children may have repeated, often unrecognized, neurologic crises lasting one to seven days that can include change in mental status, abdominal pain, peripheral neuropathy, and/or respiratory failure requiring mechanical ventilation. Death in the untreated child usually occurs before age ten years, typically from liver failure, neurologic crisis, or hepatocellular carcinoma. Combined treatment with nitisinone and a low-tyrosine diet has resulted in a greater than 90% survival rate, normal growth, improved liver function, prevention of cirrhosis, correction of renal tubular acidosis, and improvement in secondary rickets.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/75688">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_220887"><div><strong>Hereditary mucoepithelial dysplasia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>220887</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1274795</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary mucoepithelial dysplasia (HMD) is a rare autosomal dominant genodermatosis characterized by onset in infancy of a panepithelial defect involving the oral, nasal, conjunctival, vaginal, cervical, perineal, urethral, and bladder mucosa. Patients develop cataracts, blindness, nonscarring alopecia, perineal psoriasiform lesions, and follicular keratoses (Witkop et al., 1982). Although 1 family was reported to have progressive severe interstitial lung disease (Witkop et al., 1979), this feature has not been reported in other families and is not considered a criterion for diagnosis. However, the clinical triad of nonscarring alopecia, well-demarcated fiery red mucosa, and psoriasiform perineal involvement has been consistently observed (review by Boralevi et al., 2005).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/220887">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_324960"><div><strong>Telangiectasia, hereditary hemorrhagic, type 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>324960</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1838163</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary hemorrhagic telangiectasia (HHT) is characterized by the presence of multiple arteriovenous malformations (AVMs) that lack intervening capillaries and result in direct connections between arteries and veins. The most common clinical manifestation is spontaneous and recurrent nosebleeds (epistaxis) beginning on average at age 12 years. Telangiectases (small AVMs) are characteristically found on the lips, tongue, buccal and gastrointestinal (GI) mucosa, face, and fingers. The appearance of telangiectases is generally later than epistaxis but may be during childhood. Large AVMs occur most often in the lungs, liver, or brain; complications from bleeding or shunting may be sudden and catastrophic. A minority of individuals with HHT have GI bleeding, which is rarely seen before age 50 years.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/324960">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1643786"><div><strong>Telangiectasia, hereditary hemorrhagic, type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1643786</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551861</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary hemorrhagic telangiectasia (HHT) is characterized by the presence of multiple arteriovenous malformations (AVMs) that lack intervening capillaries and result in direct connections between arteries and veins. The most common clinical manifestation is spontaneous and recurrent nosebleeds (epistaxis) beginning on average at age 12 years. Telangiectases (small AVMs) are characteristically found on the lips, tongue, buccal and gastrointestinal (GI) mucosa, face, and fingers. The appearance of telangiectases is generally later than epistaxis but may be during childhood. Large AVMs occur most often in the lungs, liver, or brain; complications from bleeding or shunting may be sudden and catastrophic. A minority of individuals with HHT have GI bleeding, which is rarely seen before age 50 years.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1643786">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1657285"><div><strong>Gastric adenocarcinoma and proximal polyposis of the stomach</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1657285</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4749917</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">APC-associated polyposis conditions include (classic or attenuated) familial adenomatous polyposis (FAP) and gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS). FAP is a colorectal cancer (CRC) predisposition syndrome that can manifest in either classic or attenuated form. Classic FAP is characterized by hundreds to thousands of adenomatous colonic polyps, beginning on average at age 16 years (range 7-36 years). For those with the classic form of FAP, 95% of individuals have polyps by age 35 years; CRC is inevitable without colectomy. The mean age of CRC diagnosis in untreated individuals is 39 years (range 34-43 years). The attenuated form is characterized by multiple colonic polyps (average of 30), more proximally located polyps, and a diagnosis of CRC at a later age than in classic FAP. For those with an attenuated form, there is a 70% lifetime risk of CRC and the mean age of diagnosis is 50-55 years. Extracolonic manifestations are variably present and include polyps of the stomach and duodenum, osteomas, dental abnormalities, congenital hypertrophy of the retinal pigment epithelium (CHRPE), benign cutaneous lesions, desmoid tumors, adrenal masses, and other associated cancers. GAPPS is characterized by proximal gastric polyposis, increased risk of gastric adenocarcinoma, and no duodenal or colonic involvement in most individuals reported.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1657285">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1657285" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Gastric adenocarcinoma and proximal polyposis of the stomach</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_945" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary factor IX deficiency disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_5501" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary factor VIII deficiency disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_220887" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary mucoepithelial dysplasia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1643786" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Telangiectasia, hereditary hemorrhagic, type 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_324960" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Telangiectasia, hereditary hemorrhagic, type 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_75688" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Tyrosinemia type I</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_21921" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Wiskott-Aldrich syndrome</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36948753">Gastrointestinal Bleeding in Children: Current Management, Controversies, and Advances.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Novak I,
|
||
Bass LM</span><br />
|
||
<span class="medgenPMjournal">Gastrointest Endosc Clin N Am</span>
|
||
2023 Apr;33(2):401-421.
|
||
doi: 10.1016/j.giec.2022.11.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36948753" target="_blank">36948753</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32109037">Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wilkins T,
|
||
Wheeler B,
|
||
Carpenter M</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2020 Mar 1;101(5):294-300.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32109037" target="_blank">32109037</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30947833">Upper Gastrointestinal Bleeding: Etiologies and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kamboj AK,
|
||
Hoversten P,
|
||
Leggett CL</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
2019 Apr;94(4):697-703.
|
||
doi: 10.1016/j.mayocp.2019.01.022.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30947833" target="_blank">30947833</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22melena%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (77)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33213769">Upper Gastrointestinal Bleeding.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Costable NJ,
|
||
Greenwald DA</span><br />
|
||
<span class="medgenPMjournal">Clin Geriatr Med</span>
|
||
2021 Feb;37(1):155-172.
|
||
doi: 10.1016/j.cger.2020.09.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33213769" target="_blank">33213769</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31247176">An Unusual Thrombocytopenia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gao J,
|
||
Soleimani A,
|
||
Law J</span><br />
|
||
<span class="medgenPMjournal">Am J Med</span>
|
||
2019 Dec;132(12):e815-e816.
|
||
Epub 2019 Jun 24
|
||
doi: 10.1016/j.amjmed.2019.05.044.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31247176" target="_blank">31247176</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30947833">Upper Gastrointestinal Bleeding: Etiologies and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kamboj AK,
|
||
Hoversten P,
|
||
Leggett CL</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
2019 Apr;94(4):697-703.
|
||
doi: 10.1016/j.mayocp.2019.01.022.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30947833" target="_blank">30947833</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23281973">Transfusion strategies for acute upper gastrointestinal bleeding.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Villanueva C,
|
||
Colomo A,
|
||
Bosch A,
|
||
Concepción M,
|
||
Hernandez-Gea V,
|
||
Aracil C,
|
||
Graupera I,
|
||
Poca M,
|
||
Alvarez-Urturi C,
|
||
Gordillo J,
|
||
Guarner-Argente C,
|
||
Santaló M,
|
||
Muñiz E,
|
||
Guarner C</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2013 Jan 3;368(1):11-21.
|
||
doi: 10.1056/NEJMoa1211801.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23281973" target="_blank">23281973</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21515178">Gastrointestinal bleeding.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kumar R,
|
||
Mills AM</span><br />
|
||
<span class="medgenPMjournal">Emerg Med Clin North Am</span>
|
||
2011 May;29(2):239-52, viii.
|
||
doi: 10.1016/j.emc.2011.01.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21515178" target="_blank">21515178</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Melena%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (791)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37349077">Woman With Melena and Nausea.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yang X,
|
||
Xu L,
|
||
Liang C,
|
||
Yang L</span><br />
|
||
<span class="medgenPMjournal">Ann Emerg Med</span>
|
||
2023 Jul;82(1):e13-e14.
|
||
doi: 10.1016/j.annemergmed.2023.01.031.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37349077" target="_blank">37349077</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33213769">Upper Gastrointestinal Bleeding.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Costable NJ,
|
||
Greenwald DA</span><br />
|
||
<span class="medgenPMjournal">Clin Geriatr Med</span>
|
||
2021 Feb;37(1):155-172.
|
||
doi: 10.1016/j.cger.2020.09.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33213769" target="_blank">33213769</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30947833">Upper Gastrointestinal Bleeding: Etiologies and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kamboj AK,
|
||
Hoversten P,
|
||
Leggett CL</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
2019 Apr;94(4):697-703.
|
||
doi: 10.1016/j.mayocp.2019.01.022.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30947833" target="_blank">30947833</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2196781">Meckel's diverticulum.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Turgeon DK,
|
||
Barnett JL</span><br />
|
||
<span class="medgenPMjournal">Am J Gastroenterol</span>
|
||
1990 Jul;85(7):777-81.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2196781" target="_blank">2196781</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4136718">Endoscopy in gastrointestinal bleeding.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Forrest JA,
|
||
Finlayson ND,
|
||
Shearman DJ</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
1974 Aug 17;2(7877):394-7.
|
||
doi: 10.1016/s0140-6736(74)91770-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4136718" target="_blank">4136718</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Melena%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1702)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36948753">Gastrointestinal Bleeding in Children: Current Management, Controversies, and Advances.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Novak I,
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Bass LM</span><br />
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<span class="medgenPMjournal">Gastrointest Endosc Clin N Am</span>
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2023 Apr;33(2):401-421.
|
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doi: 10.1016/j.giec.2022.11.003.
|
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<span class="bold">PMID: </span><a href="/pubmed/36948753" target="_blank">36948753</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/33213769">Upper Gastrointestinal Bleeding.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Costable NJ,
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Greenwald DA</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/33213769" target="_blank">33213769</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/31247176">An Unusual Thrombocytopenia.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gao J,
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Soleimani A,
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<div class="portlet_content ln"><span class="medgenPMauthor">Butt MU,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Melena%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (850)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38263189">Gastrointestinal bleeding in children: diagnostic approach.</a></div>
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doi: 10.1186/s13052-024-01592-2.
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<span class="bold">PMID: </span><a href="/pubmed/38263189" target="_blank">38263189</a><a href="/pmc/articles/PMC10807079" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/26118584">Deadly Air.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Coremans L,
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Van Der Meersch F,
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Colle I,
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2015 Jan-Mar;78(1):69.
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<span class="bold">PMID: </span><a href="/pubmed/26118584" target="_blank">26118584</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/22416103">Does this patient have a severe upper gastrointestinal bleed?</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Srygley FD,
|
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Gerardo CJ,
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Tran T,
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Fisher DA</span><br />
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<span class="medgenPMjournal">JAMA</span>
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2012 Mar 14;307(10):1072-9.
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doi: 10.1001/jama.2012.253.
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<span class="bold">PMID: </span><a href="/pubmed/22416103" target="_blank">22416103</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/21515178">Gastrointestinal bleeding.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kumar R,
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<div class="nl"><a target="_blank" href="/pubmed/16393207">Rodeo endoscopy.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Scott LD</span><br />
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2005 Dec;100(12):2611.
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<span class="bold">PMID: </span><a href="/pubmed/16393207" target="_blank">16393207</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Melena%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (631)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/34627388">Clinical predictors of severe dengue: a systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Tsheten T,
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Clements ACA,
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Gray DJ,
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Adhikary RK,
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Furuya-Kanamori L,
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Wangdi K</span><br />
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<span class="medgenPMjournal">Infect Dis Poverty</span>
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2021 Oct 9;10(1):123.
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doi: 10.1186/s40249-021-00908-2.
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<span class="bold">PMID: </span><a href="/pubmed/34627388" target="_blank">34627388</a><a href="/pmc/articles/PMC8501593" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/33213769">Upper Gastrointestinal Bleeding.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Costable NJ,
|
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Greenwald DA</span><br />
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<span class="medgenPMjournal">Clin Geriatr Med</span>
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2021 Feb;37(1):155-172.
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doi: 10.1016/j.cger.2020.09.001.
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<span class="bold">PMID: </span><a href="/pubmed/33213769" target="_blank">33213769</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/32109037">Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Wilkins T,
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Wheeler B,
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Carpenter M</span><br />
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<span class="medgenPMjournal">Am Fam Physician</span>
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2020 Mar 1;101(5):294-300.
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<span class="bold">PMID: </span><a href="/pubmed/32109037" target="_blank">32109037</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/22416103">Does this patient have a severe upper gastrointestinal bleed?</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Srygley FD,
|
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Gerardo CJ,
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Tran T,
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Fisher DA</span><br />
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<span class="medgenPMjournal">JAMA</span>
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2012 Mar 14;307(10):1072-9.
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doi: 10.1001/jama.2012.253.
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<span class="bold">PMID: </span><a href="/pubmed/22416103" target="_blank">22416103</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/10197501">Patent ductus venosus.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Nagano K,
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Hoshino H,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Melena%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (427)</a></div></div>
|
||
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|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37629790">The Prevalence of Gastrointestinal Bleeding in COVID-19 Patients: A Systematic Review and Meta-Analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Karlafti E,
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Tsavdaris D,
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Kotzakioulafi E,
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Protopapas AA,
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Kaiafa G,
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Netta S,
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Savopoulos C,
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Michalopoulos A,
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Paramythiotis D</span><br />
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<span class="medgenPMjournal">Medicina (Kaunas)</span>
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2023 Aug 21;59(8)
|
||
doi: 10.3390/medicina59081500.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37629790" target="_blank">37629790</a><a href="/pmc/articles/PMC10456782" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34627388">Clinical predictors of severe dengue: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tsheten T,
|
||
Clements ACA,
|
||
Gray DJ,
|
||
Adhikary RK,
|
||
Furuya-Kanamori L,
|
||
Wangdi K</span><br />
|
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<span class="medgenPMjournal">Infect Dis Poverty</span>
|
||
2021 Oct 9;10(1):123.
|
||
doi: 10.1186/s40249-021-00908-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34627388" target="_blank">34627388</a><a href="/pmc/articles/PMC8501593" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33472441">Jejunal Dieulafoy's Lesion: A Systematic Review of Evaluation, Diagnosis, and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Malik A,
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Inayat F,
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Goraya MHN,
|
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Almas T,
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Ishtiaq R,
|
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Malik S,
|
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Tarar ZI</span><br />
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<span class="medgenPMjournal">J Investig Med High Impact Case Rep</span>
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2021 Jan-Dec;9:2324709620987703.
|
||
doi: 10.1177/2324709620987703.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33472441" target="_blank">33472441</a><a href="/pmc/articles/PMC7829607" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32687691">Primary gastric melanoma in adult population: a systematic review of the literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schizas D,
|
||
Tomara N,
|
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Katsaros I,
|
||
Sakellariou S,
|
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Machairas N,
|
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Paspala A,
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Tsilimigras DI,
|
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Papanikolaou IS,
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Mantas D</span><br />
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<span class="medgenPMjournal">ANZ J Surg</span>
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2021 Mar;91(3):269-275.
|
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Epub 2020 Jul 20
|
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doi: 10.1111/ans.16160.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32687691" target="_blank">32687691</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30933549">Clinical presentations, management, and outcomes of acute esophageal necrosis: a systemic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Abdullah HM,
|
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Ullah W,
|
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Abdallah M,
|
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Khan U,
|
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Hurairah A,
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Atiq M</span><br />
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|
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|
||
<span class="bold">PMID: </span><a href="/pubmed/30933549" target="_blank">30933549</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Melena%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (11)</a></div></div>
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|
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<div class="col-lg-3 col-12">
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<p class="address_footer text-white">National Library of Medicine<br />
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<a href="https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/@38.9959508,-77.101021,17z/data=!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb:0x19156f88b27635b8!8m2!3d38.9959508!4d-77.0988323" class="text-white" target="_blank" rel="noopener noreferrer">8600 Rockville Pike<br />
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Bethesda, MD 20894</a></p>
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</div>
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<div class="col-lg-3 col-12 centered-lg">
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<p><a href="https://www.nlm.nih.gov/web_policies.html" class="text-white">Web Policies</a><br />
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||
<a href="https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office" class="text-white">FOIA</a><br />
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||
<a href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html" class="text-white" id="vdp">HHS Vulnerability Disclosure</a></p>
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||
</div>
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||
<div class="col-lg-3 col-12 centered-lg">
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<p><a class="supportLink text-white" href="https://support.nlm.nih.gov/">Help</a><br />
|
||
<a href="https://www.nlm.nih.gov/accessibility.html" class="text-white">Accessibility</a><br />
|
||
<a href="https://www.nlm.nih.gov/careers/careers.html" class="text-white">Careers</a></p>
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</div>
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</div>
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<div class="row">
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<div class="col-lg-12 centered-lg">
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<nav class="bottom-links">
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<ul class="mt-3">
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<li>
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<a class="text-white" href="//www.nlm.nih.gov/">NLM</a>
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||
</li>
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<li>
|
||
<a class="text-white" href="https://www.nih.gov/">NIH</a>
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||
</li>
|
||
<li>
|
||
<a class="text-white" href="https://www.hhs.gov/">HHS</a>
|
||
</li>
|
||
<li>
|
||
<a class="text-white" href="https://www.usa.gov/">USA.gov</a>
|
||
</li>
|
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</ul>
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</nav>
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</div>
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</div>
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</div>
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</section>
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