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||
<!--
|
||
UID=743175
|
||
ConceptID=C1960398
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">HER2 positive breast carcinoma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>743175</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1960398</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>ERBB2 Overexpressing Subtype of Breast Carcinoma; ERBB2 Overexpressing subtype of breast carcinoma; HER2 Overexpressing Breast Carcinoma; HER2 Overexpressing breast carcinoma; HER2 Overexpressing Subtype of Breast Carcinoma; HER2 Overexpressing subtype of breast carcinoma; HER2 Positive Breast Cancer; HER2 Positive breast cancer; HER2 Positive Breast Carcinoma; HER2-Positive Breast Carcinoma; HER2-positive carcinoma of breast; Her2-receptor positive breast cancer; Human epidermal growth factor 2 positive carcinoma of breast</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>HER2-positive carcinoma of breast (427685000); Human epidermal growth factor 2 positive carcinoma of breast (427685000)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0006244" target="_blank">MONDO:0006244</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A biologic subset of breast carcinoma defined by high expression of HER2, GRB7, and TRAP100, and by lack of expression of estrogen receptor (ER). [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
|
||
</div>
|
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|
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<div class="portlet mgSection" id="ID_118">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">HER2 positive breast carcinoma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/277963" ref="tree=MeSH" title="MedGen record for Epithelial neoplasm">Epithelial neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/2867" ref="tree=MeSH" title="MedGen record for Carcinoma">Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/122" ref="tree=MeSH" title="MedGen record for Adenocarcinoma">Adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/167809" ref="tree=MeSH" title="MedGen record for Breast adenocarcinoma">Breast adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/770984" ref="tree=MeSH" title="MedGen record for Breast carcinoma by gene expression profile">Breast carcinoma by gene expression profile</a></span><ul><li><span class="matched_ds">HER2 positive breast carcinoma</span><ul><li><span class="TLline"><a href="/medgen/1793161" ref="tree=MeSH" title="MedGen record for Metastatic HER2-Positive Breast Carcinoma">Metastatic HER2-Positive Breast Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1793162" ref="tree=MeSH" title="MedGen record for Advanced HER2-Positive Breast Carcinoma">Advanced HER2-Positive Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1793709" ref="tree=MeSH" title="MedGen record for Locally Advanced HER2-Positive Breast Carcinoma">Locally Advanced HER2-Positive Breast Carcinoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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|
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<div class="portlet mgSection" id="ID_105">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30429889">Theranostic pretargeted radioimmunotherapy of internalizing solid tumor antigens in human tumor xenografts in mice: Curative treatment of HER2-positive breast carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cheal SM,
|
||
Xu H,
|
||
Guo HF,
|
||
Patel M,
|
||
Punzalan B,
|
||
Fung EK,
|
||
Lee SG,
|
||
Bell M,
|
||
Singh M,
|
||
Jungbluth AA,
|
||
Zanzonico PB,
|
||
Piersigilli A,
|
||
Larson SM,
|
||
Cheung NV</span><br />
|
||
<span class="medgenPMjournal">Theranostics</span>
|
||
2018;8(18):5106-5125.
|
||
Epub 2018 Oct 6
|
||
doi: 10.7150/thno.26585.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30429889" target="_blank">30429889</a><a href="/pmc/articles/PMC6217068" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30342077">Successful intracranial delivery of trastuzumab by gene-therapy for treatment of HER2-positive breast cancer brain metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zafir-Lavie I,
|
||
Sherbo S,
|
||
Goltsman H,
|
||
Badinter F,
|
||
Yeini E,
|
||
Ofek P,
|
||
Miari R,
|
||
Tal O,
|
||
Liran A,
|
||
Shatil T,
|
||
Krispel S,
|
||
Shapir N,
|
||
Neil GA,
|
||
Benhar I,
|
||
Panet A,
|
||
Satchi-Fainaro R</span><br />
|
||
<span class="medgenPMjournal">J Control Release</span>
|
||
2018 Dec 10;291:80-89.
|
||
Epub 2018 Oct 17
|
||
doi: 10.1016/j.jconrel.2018.10.017.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30342077" target="_blank">30342077</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24308017">Trastuzumab emtansine for the treatment of HER2-positive metastatic breast cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Haddley K</span><br />
|
||
<span class="medgenPMjournal">Drugs Today (Barc)</span>
|
||
2013 Nov;49(11):701-15.
|
||
doi: 10.1358/dot.2013.49.11.2020937.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24308017" target="_blank">24308017</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22her2%20positive%20breast%20carcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (4)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34775151">Poor histologic tumor response after adjuvant therapy in basal-like HER2-positive breast carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhao D,
|
||
Fu X,
|
||
Rohr J,
|
||
Wang Y,
|
||
Li M,
|
||
Zhang X,
|
||
Qin J,
|
||
Xu M,
|
||
Li C,
|
||
Sun G,
|
||
Wang Z,
|
||
Guo S</span><br />
|
||
<span class="medgenPMjournal">Pathol Res Pract</span>
|
||
2021 Dec;228:153677.
|
||
Epub 2021 Oct 30
|
||
doi: 10.1016/j.prp.2021.153677.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34775151" target="_blank">34775151</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33423217">ER staining levels affect HER2 staining and heterogeneity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Akashi M,
|
||
Yamaguchi R,
|
||
Kusano H,
|
||
Yamaguchi M,
|
||
Akiba J,
|
||
Kakuma T,
|
||
Tanaka M,
|
||
Akagi Y,
|
||
Yano H</span><br />
|
||
<span class="medgenPMjournal">Breast Cancer</span>
|
||
2021 May;28(3):720-726.
|
||
Epub 2021 Jan 9
|
||
doi: 10.1007/s12282-020-01208-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33423217" target="_blank">33423217</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31554015">Diverse histomorphology of HER2-positive breast carcinomas based on differential ER expression.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Akashi M,
|
||
Yamaguchi R,
|
||
Kusano H,
|
||
Obara H,
|
||
Yamaguchi M,
|
||
Toh U,
|
||
Akiba J,
|
||
Kakuma T,
|
||
Tanaka M,
|
||
Akagi Y,
|
||
Yano H</span><br />
|
||
<span class="medgenPMjournal">Histopathology</span>
|
||
2020 Mar;76(4):560-571.
|
||
Epub 2020 Feb 3
|
||
doi: 10.1111/his.14003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31554015" target="_blank">31554015</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27993117">Role of Genomic Alterations in HER2 Positive Breast Carcinoma: Focus on Susceptibility and Trastuzumab-therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Singla H,
|
||
Kalra S,
|
||
Kheterpal P,
|
||
Kumar V,
|
||
Munshi A</span><br />
|
||
<span class="medgenPMjournal">Curr Cancer Drug Targets</span>
|
||
2017;17(4):344-356.
|
||
doi: 10.2174/1568009616666161216094026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27993117" target="_blank">27993117</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27462779">Gasdermin B expression predicts poor clinical outcome in HER2-positive breast cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hergueta-Redondo M,
|
||
Sarrio D,
|
||
Molina-Crespo Á,
|
||
Vicario R,
|
||
Bernadó-Morales C,
|
||
Martínez L,
|
||
Rojo-Sebastián A,
|
||
Serra-Musach J,
|
||
Mota A,
|
||
Martínez-Ramírez Á,
|
||
Castilla MÁ,
|
||
González-Martin A,
|
||
Pernas S,
|
||
Cano A,
|
||
Cortes J,
|
||
Nuciforo PG,
|
||
Peg V,
|
||
Palacios J,
|
||
Pujana MÁ,
|
||
Arribas J,
|
||
Moreno-Bueno G</span><br />
|
||
<span class="medgenPMjournal">Oncotarget</span>
|
||
2016 Aug 30;7(35):56295-56308.
|
||
doi: 10.18632/oncotarget.10787.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27462779" target="_blank">27462779</a><a href="/pmc/articles/PMC5302915" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22HER2%20positive%20breast%20carcinoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (13)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38350067">Clinical Internal Dosimetry and Biodistribution of 177 Lu-DOTA-Trastuzumab in HER2-Positive Metastatic and Locally Advanced Breast Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Narwadkar YS,
|
||
Parghane RV,
|
||
Sahu S,
|
||
Lad S,
|
||
Deep K,
|
||
Wanage G,
|
||
Suralkar T,
|
||
Banerjee S,
|
||
Gupta S,
|
||
Basu S,
|
||
Badwe RA</span><br />
|
||
<span class="medgenPMjournal">Clin Nucl Med</span>
|
||
2024 Apr 1;49(4):e149-e155.
|
||
Epub 2024 Feb 1
|
||
doi: 10.1097/RLU.0000000000005067.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38350067" target="_blank">38350067</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37204204">Predictive markers for pathological complete response (pCR) after neo-adjuvant chemotherapy in HER2-positive breast carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Van Bockstal MR,
|
||
Dano H,
|
||
Benhaddi N,
|
||
Dubois D,
|
||
Vanderveken J,
|
||
Van Marcke C,
|
||
Vandermeulen A,
|
||
Duhoux FP,
|
||
Vernaeve H,
|
||
Berlière M,
|
||
Galant C</span><br />
|
||
<span class="medgenPMjournal">Histol Histopathol</span>
|
||
2024 Feb;39(2):153-164.
|
||
Epub 2023 May 10
|
||
doi: 10.14670/HH-18-626.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37204204" target="_blank">37204204</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32237061">rBC2LCN lectin as a potential probe of early-stage HER2-positive breast carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mawaribuchi S,
|
||
Haramoto Y,
|
||
Tateno H,
|
||
Onuma Y,
|
||
Aiki Y,
|
||
Ito Y</span><br />
|
||
<span class="medgenPMjournal">FEBS Open Bio</span>
|
||
2020 Jun;10(6):1056-1064.
|
||
Epub 2020 May 5
|
||
doi: 10.1002/2211-5463.12852.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32237061" target="_blank">32237061</a><a href="/pmc/articles/PMC7262912" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27993117">Role of Genomic Alterations in HER2 Positive Breast Carcinoma: Focus on Susceptibility and Trastuzumab-therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Singla H,
|
||
Kalra S,
|
||
Kheterpal P,
|
||
Kumar V,
|
||
Munshi A</span><br />
|
||
<span class="medgenPMjournal">Curr Cancer Drug Targets</span>
|
||
2017;17(4):344-356.
|
||
doi: 10.2174/1568009616666161216094026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27993117" target="_blank">27993117</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26449837">Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Keyaerts M,
|
||
Xavier C,
|
||
Heemskerk J,
|
||
Devoogdt N,
|
||
Everaert H,
|
||
Ackaert C,
|
||
Vanhoeij M,
|
||
Duhoux FP,
|
||
Gevaert T,
|
||
Simon P,
|
||
Schallier D,
|
||
Fontaine C,
|
||
Vaneycken I,
|
||
Vanhove C,
|
||
De Greve J,
|
||
Lamote J,
|
||
Caveliers V,
|
||
Lahoutte T</span><br />
|
||
<span class="medgenPMjournal">J Nucl Med</span>
|
||
2016 Jan;57(1):27-33.
|
||
Epub 2015 Oct 8
|
||
doi: 10.2967/jnumed.115.162024.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26449837" target="_blank">26449837</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22HER2%20positive%20breast%20carcinoma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34775151">Poor histologic tumor response after adjuvant therapy in basal-like HER2-positive breast carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhao D,
|
||
Fu X,
|
||
Rohr J,
|
||
Wang Y,
|
||
Li M,
|
||
Zhang X,
|
||
Qin J,
|
||
Xu M,
|
||
Li C,
|
||
Sun G,
|
||
Wang Z,
|
||
Guo S</span><br />
|
||
<span class="medgenPMjournal">Pathol Res Pract</span>
|
||
2021 Dec;228:153677.
|
||
Epub 2021 Oct 30
|
||
doi: 10.1016/j.prp.2021.153677.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34775151" target="_blank">34775151</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32237061">rBC2LCN lectin as a potential probe of early-stage HER2-positive breast carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mawaribuchi S,
|
||
Haramoto Y,
|
||
Tateno H,
|
||
Onuma Y,
|
||
Aiki Y,
|
||
Ito Y</span><br />
|
||
<span class="medgenPMjournal">FEBS Open Bio</span>
|
||
2020 Jun;10(6):1056-1064.
|
||
Epub 2020 May 5
|
||
doi: 10.1002/2211-5463.12852.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32237061" target="_blank">32237061</a><a href="/pmc/articles/PMC7262912" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27993117">Role of Genomic Alterations in HER2 Positive Breast Carcinoma: Focus on Susceptibility and Trastuzumab-therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Singla H,
|
||
Kalra S,
|
||
Kheterpal P,
|
||
Kumar V,
|
||
Munshi A</span><br />
|
||
<span class="medgenPMjournal">Curr Cancer Drug Targets</span>
|
||
2017;17(4):344-356.
|
||
doi: 10.2174/1568009616666161216094026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27993117" target="_blank">27993117</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26449837">Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Keyaerts M,
|
||
Xavier C,
|
||
Heemskerk J,
|
||
Devoogdt N,
|
||
Everaert H,
|
||
Ackaert C,
|
||
Vanhoeij M,
|
||
Duhoux FP,
|
||
Gevaert T,
|
||
Simon P,
|
||
Schallier D,
|
||
Fontaine C,
|
||
Vaneycken I,
|
||
Vanhove C,
|
||
De Greve J,
|
||
Lamote J,
|
||
Caveliers V,
|
||
Lahoutte T</span><br />
|
||
<span class="medgenPMjournal">J Nucl Med</span>
|
||
2016 Jan;57(1):27-33.
|
||
Epub 2015 Oct 8
|
||
doi: 10.2967/jnumed.115.162024.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26449837" target="_blank">26449837</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24308017">Trastuzumab emtansine for the treatment of HER2-positive metastatic breast cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Haddley K</span><br />
|
||
<span class="medgenPMjournal">Drugs Today (Barc)</span>
|
||
2013 Nov;49(11):701-15.
|
||
doi: 10.1358/dot.2013.49.11.2020937.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24308017" target="_blank">24308017</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22HER2%20positive%20breast%20carcinoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (17)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37268505">Molecular Classification of Breast Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Roy M,
|
||
Fowler AM,
|
||
Ulaner GA,
|
||
Mahajan A</span><br />
|
||
<span class="medgenPMjournal">PET Clin</span>
|
||
2023 Oct;18(4):441-458.
|
||
Epub 2023 May 31
|
||
doi: 10.1016/j.cpet.2023.04.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37268505" target="_blank">37268505</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31554015">Diverse histomorphology of HER2-positive breast carcinomas based on differential ER expression.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Akashi M,
|
||
Yamaguchi R,
|
||
Kusano H,
|
||
Obara H,
|
||
Yamaguchi M,
|
||
Toh U,
|
||
Akiba J,
|
||
Kakuma T,
|
||
Tanaka M,
|
||
Akagi Y,
|
||
Yano H</span><br />
|
||
<span class="medgenPMjournal">Histopathology</span>
|
||
2020 Mar;76(4):560-571.
|
||
Epub 2020 Feb 3
|
||
doi: 10.1111/his.14003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31554015" target="_blank">31554015</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27993117">Role of Genomic Alterations in HER2 Positive Breast Carcinoma: Focus on Susceptibility and Trastuzumab-therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Singla H,
|
||
Kalra S,
|
||
Kheterpal P,
|
||
Kumar V,
|
||
Munshi A</span><br />
|
||
<span class="medgenPMjournal">Curr Cancer Drug Targets</span>
|
||
2017;17(4):344-356.
|
||
doi: 10.2174/1568009616666161216094026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27993117" target="_blank">27993117</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26449837">Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Keyaerts M,
|
||
Xavier C,
|
||
Heemskerk J,
|
||
Devoogdt N,
|
||
Everaert H,
|
||
Ackaert C,
|
||
Vanhoeij M,
|
||
Duhoux FP,
|
||
Gevaert T,
|
||
Simon P,
|
||
Schallier D,
|
||
Fontaine C,
|
||
Vaneycken I,
|
||
Vanhove C,
|
||
De Greve J,
|
||
Lamote J,
|
||
Caveliers V,
|
||
Lahoutte T</span><br />
|
||
<span class="medgenPMjournal">J Nucl Med</span>
|
||
2016 Jan;57(1):27-33.
|
||
Epub 2015 Oct 8
|
||
doi: 10.2967/jnumed.115.162024.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26449837" target="_blank">26449837</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24308017">Trastuzumab emtansine for the treatment of HER2-positive metastatic breast cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Haddley K</span><br />
|
||
<span class="medgenPMjournal">Drugs Today (Barc)</span>
|
||
2013 Nov;49(11):701-15.
|
||
doi: 10.1358/dot.2013.49.11.2020937.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24308017" target="_blank">24308017</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22HER2%20positive%20breast%20carcinoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (16)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37268505">Molecular Classification of Breast Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Roy M,
|
||
Fowler AM,
|
||
Ulaner GA,
|
||
Mahajan A</span><br />
|
||
<span class="medgenPMjournal">PET Clin</span>
|
||
2023 Oct;18(4):441-458.
|
||
Epub 2023 May 31
|
||
doi: 10.1016/j.cpet.2023.04.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37268505" target="_blank">37268505</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31554015">Diverse histomorphology of HER2-positive breast carcinomas based on differential ER expression.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Akashi M,
|
||
Yamaguchi R,
|
||
Kusano H,
|
||
Obara H,
|
||
Yamaguchi M,
|
||
Toh U,
|
||
Akiba J,
|
||
Kakuma T,
|
||
Tanaka M,
|
||
Akagi Y,
|
||
Yano H</span><br />
|
||
<span class="medgenPMjournal">Histopathology</span>
|
||
2020 Mar;76(4):560-571.
|
||
Epub 2020 Feb 3
|
||
doi: 10.1111/his.14003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31554015" target="_blank">31554015</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27993117">Role of Genomic Alterations in HER2 Positive Breast Carcinoma: Focus on Susceptibility and Trastuzumab-therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Singla H,
|
||
Kalra S,
|
||
Kheterpal P,
|
||
Kumar V,
|
||
Munshi A</span><br />
|
||
<span class="medgenPMjournal">Curr Cancer Drug Targets</span>
|
||
2017;17(4):344-356.
|
||
doi: 10.2174/1568009616666161216094026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27993117" target="_blank">27993117</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26449837">Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Keyaerts M,
|
||
Xavier C,
|
||
Heemskerk J,
|
||
Devoogdt N,
|
||
Everaert H,
|
||
Ackaert C,
|
||
Vanhoeij M,
|
||
Duhoux FP,
|
||
Gevaert T,
|
||
Simon P,
|
||
Schallier D,
|
||
Fontaine C,
|
||
Vaneycken I,
|
||
Vanhove C,
|
||
De Greve J,
|
||
Lamote J,
|
||
Caveliers V,
|
||
Lahoutte T</span><br />
|
||
<span class="medgenPMjournal">J Nucl Med</span>
|
||
2016 Jan;57(1):27-33.
|
||
Epub 2015 Oct 8
|
||
doi: 10.2967/jnumed.115.162024.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26449837" target="_blank">26449837</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24308017">Trastuzumab emtansine for the treatment of HER2-positive metastatic breast cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Haddley K</span><br />
|
||
<span class="medgenPMjournal">Drugs Today (Barc)</span>
|
||
2013 Nov;49(11):701-15.
|
||
doi: 10.1358/dot.2013.49.11.2020937.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24308017" target="_blank">24308017</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22HER2%20positive%20breast%20carcinoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (16)</a></div></div>
|
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|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=HER2%20positive%20breast%20carcinoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22her2%20positive%20breast%20carcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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