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<meta name="keywords" content="C0023437, acute basophilic leukemia, acute basophilic leukemias, basophilic leukaemia, basophilic leukemia, basophilic leukemia, acute, basophilic leukemias, acute, leukaemia basophilic, leukemia basophilic, leukemia, acute basophilic, leukemia, basophilic, acute, leukemias, acute basophilic, neoplastic process, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A rare acute myeloid leukemia characterized by primary differentiation to basophils. Microscopically, peripheral blood and bone marrow blasts contain coarse cytoplasmic basophilic granules which are positive with metachromatic staining (toluidine blue). Electron microscopy confirms that granules show features characteristic of basophil precursors. Mature basophils are usually sparse. Patients may present with manifestations related to bone marrow failure, as well as hepatosplenomegaly, cutaneous involvement, lytic lesions, and hyperhistaminemia. The disease is associated with a poor prognosis." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=7314
|
||
ConceptID=C0023437
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Acute basophilic leukemia</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>7314</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0023437</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Acute Basophilic Leukemia; Acute Basophilic Leukemias; Basophilic Leukemia, Acute; Basophilic Leukemias, Acute; Leukemia, Acute Basophilic; Leukemia, Basophilic, Acute; Leukemias, Acute Basophilic</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Acute basophilic leukemia (69077002)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0019458" target="_blank">MONDO:0019458</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=86849">ORPHA86849</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A rare acute myeloid leukemia characterized by primary differentiation to basophils. Microscopically, peripheral blood and bone marrow blasts contain coarse cytoplasmic basophilic granules which are positive with metachromatic staining (toluidine blue). Electron microscopy confirms that granules show features characteristic of basophil precursors. Mature basophils are usually sparse. Patients may present with manifestations related to bone marrow failure, as well as hepatosplenomegaly, cutaneous involvement, lytic lesions, and hyperhistaminemia. The disease is associated with a poor prognosis. [from <a title="Orphanet Rare Disease Ontology (ORDO)" href="http://www.orphadata.org/cgi-bin/inc/ordo_orphanet.inc.php" class="defSource" target="_blank">ORDO</a>]</div>
|
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Acute basophilic leukemia</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/208860" ref="tree=MeSH" title="MedGen record for Hematopoietic and Lymphatic System Disorder">Hematopoietic and Lymphatic System Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/5483" ref="tree=MeSH" title="MedGen record for Hematologic disorder">Hematologic disorder</a></span><ul><li><span class="TLline"><a href="/medgen/138213" ref="tree=MeSH" title="MedGen record for Hematologic neoplasm">Hematologic neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/9725" ref="tree=MeSH" title="MedGen record for Leukemia">Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/43225" ref="tree=MeSH" title="MedGen record for Acute leukemia">Acute leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/9730" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia">Acute myeloid leukemia</a></span><ul><li><span class="matched_ds">Acute basophilic leukemia</span><ul><li><span class="TLline"><a href="/medgen/124637" ref="tree=MeSH" title="MedGen record for Adult Acute Basophilic Leukemia">Adult Acute Basophilic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/83536" ref="tree=MeSH" title="MedGen record for Childhood Acute Basophilic Leukemia">Childhood Acute Basophilic Leukemia</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=11754&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Acute basophilic leukemia</span> in Orphanet.</div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28090091">Proposed diagnostic criteria and classification of basophilic leukemias and related disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Valent P,
|
||
Sotlar K,
|
||
Blatt K,
|
||
Hartmann K,
|
||
Reiter A,
|
||
Sadovnik I,
|
||
Sperr WR,
|
||
Bettelheim P,
|
||
Akin C,
|
||
Bauer K,
|
||
George TI,
|
||
Hadzijusufovic E,
|
||
Wolf D,
|
||
Gotlib J,
|
||
Mahon FX,
|
||
Metcalfe DD,
|
||
Horny HP,
|
||
Arock M</span><br />
|
||
<span class="medgenPMjournal">Leukemia</span>
|
||
2017 Apr;31(4):788-797.
|
||
Epub 2017 Jan 16
|
||
doi: 10.1038/leu.2017.15.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28090091" target="_blank">28090091</a><a href="/pmc/articles/PMC7115817" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25025369">Myelomastocytic leukemia: histopathological features, diagnostic criteria and differential diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Horny HP,
|
||
Sotlar K,
|
||
Reiter A,
|
||
Valent P</span><br />
|
||
<span class="medgenPMjournal">Expert Rev Hematol</span>
|
||
2014 Aug;7(4):431-7.
|
||
doi: 10.1586/17474086.2014.942280.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25025369" target="_blank">25025369</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22acute%20basophilic%20leukemia%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (2)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37702688">Complex Karyotype Acute Basophilic Leukemia with Reactive Mast Cell Hyperplasia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wu Y,
|
||
Zhang X,
|
||
Guo H,
|
||
Guo J,
|
||
Li R</span><br />
|
||
<span class="medgenPMjournal">Clin Lab</span>
|
||
2023 Sep 1;69(9)
|
||
doi: 10.7754/Clin.Lab.2023.230337.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37702688" target="_blank">37702688</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25025369">Myelomastocytic leukemia: histopathological features, diagnostic criteria and differential diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Horny HP,
|
||
Sotlar K,
|
||
Reiter A,
|
||
Valent P</span><br />
|
||
<span class="medgenPMjournal">Expert Rev Hematol</span>
|
||
2014 Aug;7(4):431-7.
|
||
doi: 10.1586/17474086.2014.942280.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25025369" target="_blank">25025369</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16189800">Allergenic characteristics of a modified peanut allergen.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">King N,
|
||
Helm R,
|
||
Stanley JS,
|
||
Vieths S,
|
||
Lüttkopf D,
|
||
Hatahet L,
|
||
Sampson H,
|
||
Pons L,
|
||
Burks W,
|
||
Bannon GA</span><br />
|
||
<span class="medgenPMjournal">Mol Nutr Food Res</span>
|
||
2005 Oct;49(10):963-71.
|
||
doi: 10.1002/mnfr.200500073.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16189800" target="_blank">16189800</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11377685">Myelomastocytic overlap syndromes: biology, criteria, and relationship to mastocytosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Valent P,
|
||
Sperr WR,
|
||
Samorapoompichit P,
|
||
Geissler K,
|
||
Lechner K,
|
||
Horny HP,
|
||
Bennett JM</span><br />
|
||
<span class="medgenPMjournal">Leuk Res</span>
|
||
2001 Jul;25(7):595-602.
|
||
doi: 10.1016/s0145-2126(01)00040-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11377685" target="_blank">11377685</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1862771">Acute basophilic leukemia. A clinical, morphologic, and cytogenetic study of eight cases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Peterson LC,
|
||
Parkin JL,
|
||
Arthur DC,
|
||
Brunning RD</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Pathol</span>
|
||
1991 Aug;96(2):160-70.
|
||
doi: 10.1093/ajcp/96.2.160.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1862771" target="_blank">1862771</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Acute%20basophilic%20leukemia%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (19)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34689541">Acute Basophilic Leukemia Arising from Chronic Myeloid Leukemia with Isolated Thrombocytosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang Y,
|
||
Kang X,
|
||
Chen X,
|
||
Li T</span><br />
|
||
<span class="medgenPMjournal">Turk J Haematol</span>
|
||
2021 Dec 7;38(4):341-343.
|
||
Epub 2021 Oct 25
|
||
doi: 10.4274/tjh.galenos.2021.2021.0546.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34689541" target="_blank">34689541</a><a href="/pmc/articles/PMC8656129" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28090091">Proposed diagnostic criteria and classification of basophilic leukemias and related disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Valent P,
|
||
Sotlar K,
|
||
Blatt K,
|
||
Hartmann K,
|
||
Reiter A,
|
||
Sadovnik I,
|
||
Sperr WR,
|
||
Bettelheim P,
|
||
Akin C,
|
||
Bauer K,
|
||
George TI,
|
||
Hadzijusufovic E,
|
||
Wolf D,
|
||
Gotlib J,
|
||
Mahon FX,
|
||
Metcalfe DD,
|
||
Horny HP,
|
||
Arock M</span><br />
|
||
<span class="medgenPMjournal">Leukemia</span>
|
||
2017 Apr;31(4):788-797.
|
||
Epub 2017 Jan 16
|
||
doi: 10.1038/leu.2017.15.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28090091" target="_blank">28090091</a><a href="/pmc/articles/PMC7115817" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24941894">Acute myeloid leukemia with myelodysplasia-related changes showing basophilic differentiation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wells R,
|
||
Williams B,
|
||
Bain BJ</span><br />
|
||
<span class="medgenPMjournal">Am J Hematol</span>
|
||
2014 Nov;89(11):1082.
|
||
Epub 2014 Jun 27
|
||
doi: 10.1002/ajh.23789.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24941894" target="_blank">24941894</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21576634">Acute basophilic leukemia associated with loss of gene ETV6 and protean complications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kritharis A,
|
||
Brody J,
|
||
Koduru P,
|
||
Teichberg S,
|
||
Allen SL</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2011 Jul 20;29(21):e623-6.
|
||
Epub 2011 May 16
|
||
doi: 10.1200/JCO.2010.34.5710.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21576634" target="_blank">21576634</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11722593">Acute basophilic leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Giagounidis AA,
|
||
Hildebrandt B,
|
||
Heinsch M,
|
||
Germing U,
|
||
Aivado M,
|
||
Aul C</span><br />
|
||
<span class="medgenPMjournal">Eur J Haematol</span>
|
||
2001 Aug;67(2):72-6.
|
||
doi: 10.1034/j.1600-0609.2001.t01-1-00487.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11722593" target="_blank">11722593</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Acute%20basophilic%20leukemia%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (44)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30599775">c-MYB and DMTF1 in Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fry EA,
|
||
Inoue K</span><br />
|
||
<span class="medgenPMjournal">Cancer Invest</span>
|
||
2019;37(1):46-65.
|
||
Epub 2019 Jan 2
|
||
doi: 10.1080/07357907.2018.1550090.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30599775" target="_blank">30599775</a><a href="/pmc/articles/PMC6431554" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24949509">Acute basophilic leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Eveillard M,
|
||
Desjonqueres A</span><br />
|
||
<span class="medgenPMjournal">Blood</span>
|
||
2014 May 15;123(20):3071.
|
||
doi: 10.1182/blood-2014-02-555698.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24949509" target="_blank">24949509</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23422134">Arsenic trioxide in treatment of de novo acute basophilic leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhao YH,
|
||
Kong DS,
|
||
Han LN,
|
||
Hu LH,
|
||
Zhang Z,
|
||
Liu JJ,
|
||
Liu SX,
|
||
Qin F,
|
||
Zhou J</span><br />
|
||
<span class="medgenPMjournal">Chin Med J (Engl)</span>
|
||
2013 Feb;126(3):593-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23422134" target="_blank">23422134</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21576634">Acute basophilic leukemia associated with loss of gene ETV6 and protean complications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kritharis A,
|
||
Brody J,
|
||
Koduru P,
|
||
Teichberg S,
|
||
Allen SL</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2011 Jul 20;29(21):e623-6.
|
||
Epub 2011 May 16
|
||
doi: 10.1200/JCO.2010.34.5710.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21576634" target="_blank">21576634</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11722593">Acute basophilic leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Giagounidis AA,
|
||
Hildebrandt B,
|
||
Heinsch M,
|
||
Germing U,
|
||
Aivado M,
|
||
Aul C</span><br />
|
||
<span class="medgenPMjournal">Eur J Haematol</span>
|
||
2001 Aug;67(2):72-6.
|
||
doi: 10.1034/j.1600-0609.2001.t01-1-00487.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11722593" target="_blank">11722593</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Acute%20basophilic%20leukemia%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/21576634">Acute basophilic leukemia associated with loss of gene ETV6 and protean complications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kritharis A,
|
||
Brody J,
|
||
Koduru P,
|
||
Teichberg S,
|
||
Allen SL</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2011 Jul 20;29(21):e623-6.
|
||
Epub 2011 May 16
|
||
doi: 10.1200/JCO.2010.34.5710.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21576634" target="_blank">21576634</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18958792">Metabolic patterns (NAD(P)H) in rat basophilic leukemia (RBL-2H3) cells and human hepatocellular carcinoma (Hep G2) cells with autofluorescence imaging.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen R,
|
||
Chen JY,
|
||
Zhou LW</span><br />
|
||
<span class="medgenPMjournal">Ultrastruct Pathol</span>
|
||
2008 Sep-Oct;32(5):193-8.
|
||
doi: 10.1080/01913120802397752.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18958792" target="_blank">18958792</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15164378">Acute basophilic leukemia: case report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta R,
|
||
Jain P,
|
||
Anand M</span><br />
|
||
<span class="medgenPMjournal">Am J Hematol</span>
|
||
2004 Jun;76(2):134-8.
|
||
doi: 10.1002/ajh.10446.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15164378" target="_blank">15164378</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11722593">Acute basophilic leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Giagounidis AA,
|
||
Hildebrandt B,
|
||
Heinsch M,
|
||
Germing U,
|
||
Aivado M,
|
||
Aul C</span><br />
|
||
<span class="medgenPMjournal">Eur J Haematol</span>
|
||
2001 Aug;67(2):72-6.
|
||
doi: 10.1034/j.1600-0609.2001.t01-1-00487.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11722593" target="_blank">11722593</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9130639">Engagement of a T cell receptor by major histocompatibility complex irrespective of peptide.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vessey SJ,
|
||
Barouch DH,
|
||
McAdam SN,
|
||
Tussey LG,
|
||
Davenport MA,
|
||
O'Callaghan CA,
|
||
Bell JI,
|
||
McMichael AJ,
|
||
Jakobsen BK</span><br />
|
||
<span class="medgenPMjournal">Eur J Immunol</span>
|
||
1997 Apr;27(4):879-85.
|
||
doi: 10.1002/eji.1830270412.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9130639" target="_blank">9130639</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Acute%20basophilic%20leukemia%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/11722593">Acute basophilic leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Giagounidis AA,
|
||
Hildebrandt B,
|
||
Heinsch M,
|
||
Germing U,
|
||
Aivado M,
|
||
Aul C</span><br />
|
||
<span class="medgenPMjournal">Eur J Haematol</span>
|
||
2001 Aug;67(2):72-6.
|
||
doi: 10.1034/j.1600-0609.2001.t01-1-00487.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11722593" target="_blank">11722593</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9886363">Human myeloid cells express an activating ILT receptor (ILT1) that associates with Fc receptor gamma-chain.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nakajima H,
|
||
Samaridis J,
|
||
Angman L,
|
||
Colonna M</span><br />
|
||
<span class="medgenPMjournal">J Immunol</span>
|
||
1999 Jan 1;162(1):5-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9886363" target="_blank">9886363</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9130639">Engagement of a T cell receptor by major histocompatibility complex irrespective of peptide.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vessey SJ,
|
||
Barouch DH,
|
||
McAdam SN,
|
||
Tussey LG,
|
||
Davenport MA,
|
||
O'Callaghan CA,
|
||
Bell JI,
|
||
McMichael AJ,
|
||
Jakobsen BK</span><br />
|
||
<span class="medgenPMjournal">Eur J Immunol</span>
|
||
1997 Apr;27(4):879-85.
|
||
doi: 10.1002/eji.1830270412.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9130639" target="_blank">9130639</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8831760">5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bhatia PA,
|
||
Brooks CD,
|
||
Basha A,
|
||
Ratajczyk JD,
|
||
Gunn BP,
|
||
Bouska JB,
|
||
Lanni C,
|
||
Young PR,
|
||
Bell RL,
|
||
Carter GW</span><br />
|
||
<span class="medgenPMjournal">J Med Chem</span>
|
||
1996 Sep 27;39(20):3938-50.
|
||
doi: 10.1021/jm960372b.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8831760" target="_blank">8831760</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7678225">Human IgE mediates stimulus secretion coupling in rat basophilic leukemia cells transfected with the alpha chain of the human high-affinity receptor.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wilson AP,
|
||
Pullar CE,
|
||
Camp AM,
|
||
Helm BA</span><br />
|
||
<span class="medgenPMjournal">Eur J Immunol</span>
|
||
1993 Jan;23(1):240-4.
|
||
doi: 10.1002/eji.1830230137.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7678225" target="_blank">7678225</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Acute%20basophilic%20leukemia%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (43)</a></div></div>
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