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106 KiB
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<!--
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UID=68698
|
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ConceptID=C0240182
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Leukonychia</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>68698</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0240182</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Leuconychia; White discoloration of nails</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Leuconychia (111202002); Leukonychia (111202002)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0001820">HP:0001820</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">White discoloration of the nails. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Leukonychia</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/871273" ref="tree=MeSH" title="MedGen record for Abnormality of the integument">Abnormality of the integument</a></span><ul><li><span class="TLline"><a href="/medgen/869100" ref="tree=MeSH" title="MedGen record for Abnormal skin adnexa morphology">Abnormal skin adnexa morphology</a></span><ul><li><span class="TLline"><a href="/medgen/163115" ref="tree=MeSH" title="MedGen record for Abnormal nail morphology">Abnormal nail morphology</a></span><ul><li><span class="TLline"><a href="/medgen/866614" ref="tree=MeSH" title="MedGen record for Abnormality of nail color">Abnormality of nail color</a></span><ul><li><span class="matched_ds">Leukonychia</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_82666"><div><strong>Atrophoderma vermiculatum</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>82666</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0263429</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Atrophoderma vermiculata, a form of keratosis pilaris atrophicans, typically presents in childhood with erythema and follicular keratotic papules that slowly progress to characteristic atrophy, which has been described as worm-eaten, reticular, or honeycomb, and occurs on the cheeks, preauricular area, and forehead. More rarely, the atrophy may extend to the upper lip, helices, ear lobes, and, in some cases, the limbs. The degree of inflammation, the presence of milia, and the extent of follicular plugs are variable (summary by Luria and Conologue, 2009).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/82666">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_82727"><div><strong>Knuckle pads, deafness AND leukonychia syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>82727</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0266004</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Bart-Pumphrey syndrome (BAPS) is an autosomal dominant disorder characterized by sensorineural hearing loss, palmoplantar keratoderma, knuckle pads, and leukonychia, which shows considerable phenotypic variability (summary by Richard et al., 2004).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/82727">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_75686"><div><strong>Hooft disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>75686</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268479</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/75686">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_140929"><div><strong>Trichorhinophalangeal dysplasia type I</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>140929</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0432233</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Trichorhinophalangeal syndrome (TRPS) comprises TRPS I (caused by a heterozygous pathogenic variant in TRPS1) and TRPS II (caused by a contiguous gene deletion of TRPS1, RAD21, and EXT1). Both TRPS types are characterized by distinctive facial features (large nose with broad nasal ridge and tip and underdeveloped alae; thick and broad medial eyebrows; long philtrum; thin vermilion of the upper lip; and large prominent ears); ectodermal features (fine, sparse, depigmented, and slow-growing hair and dystrophic nails); and skeletal findings (short stature, brachydactyly with ulnar or radial deviation of the fingers, short feet, and early, marked hip dysplasia). TRPS II is additionally characterized by multiple osteochondromas and an increased risk of mild-to-moderate intellectual disability.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/140929">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_107463"><div><strong>Nonsyndromic congenital nail disorder 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>107463</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0544855</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Any inherited isolated nail anomaly in which the cause of the disease is a mutation in the PLCD1 gene.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/107463">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_371355"><div><strong>Autosomal recessive congenital ichthyosis 4A</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>371355</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1832550</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal recessive congenital ichthyosis (ARCI) is a heterogeneous group of disorders of keratinization characterized primarily by abnormal skin scaling over the whole body. These disorders are limited to skin, with approximately two-thirds of patients presenting severe symptoms. The main skin phenotypes are lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE), although phenotypic overlap within the same patient or among patients from the same family can occur (summary by Fischer, 2009). Neither histopathologic findings nor ultrastructural features clearly distinguish between NCIE and LI. In addition, mutations in several genes have been shown to cause both lamellar and nonbullous ichthyosiform erythrodermal phenotypes (Akiyama et al., 2003). At the First Ichthyosis Consensus Conference in Soreze in 2009, the term 'autosomal recessive congenital ichthyosis' (ARCI) was designated to encompass LI, NCIE, and harlequin ichthyosis (ARCI4B; 242500) (Oji et al., 2010). NCIE is characterized by prominent erythroderma and fine white, superficial, semiadherent scales. Most patients present with collodion membrane at birth and have palmoplantar keratoderma, often with painful fissures, digital contractures, and loss of pulp volume. In half of the cases, a nail dystrophy including ridging, subungual hyperkeratosis, or hypoplasia has been described. Ectropion, eclabium, scalp involvement, and loss of eyebrows and lashes seem to be more frequent in NCIE than in lamellar ichthyosis (summary by Fischer et al., 2000). In LI, the scales are large, adherent, dark, and pigmented with no skin erythema. Overlapping phenotypes may depend on the age of the patient and the region of the body. The terminal differentiation of the epidermis is perturbed in both forms, leading to a reduced barrier function and defects of lipid composition in the stratum corneum (summary by Lefevre et al., 2006). In later life, the skin in ARCI may have scales that cover the entire body surface, including the flexural folds, and the scales are highly variable in size and color. Erythema may be very mild and almost invisible. Some affected persons exhibit scarring alopecia, and many have secondary anhidrosis (summary by Eckl et al., 2005). For a general phenotypic description and discussion of genetic heterogeneity of autosomal recessive congenital ichthyosis, see ARCI1 (242300).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/371355">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_442697"><div><strong>Hereditary hypotrichosis with recurrent skin vesicles</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>442697</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2751292</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hypotrichosis and recurrent skin vesicles (HYPTSV) is characterized by sparse to absent scalp hair, eyebrows, eyelashes, and body hair, as well as recurrent vesicles of scalp and skin. Some patients also exhibit trauma-induced blistering, and anomalies of dental enamel and of nails may be observed (Ayub et al., 2009; Onoufriadis et al., 2020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/442697">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_862830"><div><strong>Cardiomyopathy, dilated, with wooly hair, keratoderma, and tooth agenesis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>862830</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4014393</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Keratoderma with woolly hair is a group of related conditions that affect the skin and hair and in many cases increase the risk of potentially life-threatening heart problems. People with these conditions have hair that is unusually coarse, dry, fine, and tightly curled. In some cases, the hair is also sparse. The woolly hair texture typically affects only scalp hair and is present from birth. Starting early in life, affected individuals also develop palmoplantar keratoderma, a condition that causes skin on the palms of the hands and the soles of the feet to become thick, scaly, and calloused.\n\nCardiomyopathy, which is a disease of the heart muscle, is a life-threatening health problem that can develop in people with keratoderma with woolly hair. Unlike the other features of this condition, signs and symptoms of cardiomyopathy may not appear until adolescence or later. Complications of cardiomyopathy can include an abnormal heartbeat (arrhythmia), heart failure, and sudden death.\n\nKeratoderma with woolly hair comprises several related conditions with overlapping signs and symptoms. Researchers have recently proposed classifying keratoderma with woolly hair into four types, based on the underlying genetic cause. Type I, also known as Naxos disease, is characterized by palmoplantar keratoderma, woolly hair, and a form of cardiomyopathy called arrhythmogenic right ventricular cardiomyopathy (ARVC). Type II, also known as Carvajal syndrome, has hair and skin abnormalities similar to type I but features a different form of cardiomyopathy, called dilated left ventricular cardiomyopathy. Type III also has signs and symptoms similar to those of type I, including ARVC, although the hair and skin abnormalities are often milder. Type IV is characterized by palmoplantar keratoderma and woolly and sparse hair, as well as abnormal fingernails and toenails. Type IV does not appear to cause cardiomyopathy.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/862830">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_863639"><div><strong>Wooly hair-palmoplantar keratoderma syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>863639</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4015202</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Palmoplantar keratoderma and woolly hair (PPKWH) is an autosomal recessive disorder characterized by the presence of these cardinal features and the absence of cardiomyopathy symptoms or findings on echocardiography and electrocardiogram. Palmoplantar keratoderma is of the striate type; hair is generally sparse; and leukonychia is present (Ramot et al., 2014).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/863639">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_903520"><div><strong>Heimler syndrome 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>903520</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4225267</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Heimler syndrome, which represents the mildest end of the peroxisomal biogenesis disorder spectrum (see PBD1A, 214100), is a rare autosomal recessive disorder characterized by sensorineural hearing loss, enamel hypoplasia of the secondary dentition, and nail abnormalities (Ratbi et al., 2015). For a discussion of genetic heterogeneity of Heimler syndrome, see HMLR1 (234580).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/903520">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_902464"><div><strong>Peeling skin-leukonuchia-acral punctate keratoses-cheilitis-knuckle pads syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>902464</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4225381</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare genetic skin disease characterized by generalized skin peeling, leukonychia, acral punctate keratoses coalescing into focal keratoderma on the weight-bearing areas, angular cheilitis and knuckle pads with multiple hyperkeratotic micropapules. The skin appears dry and scaly with superficial exfoliation and underlying erythema. Histopathologic examination of affected skin areas shows hyperkeratosis, acanthosis and intraepidermal clefting with irregular acantholysis. Additional systemic abnormalities are absent.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/902464">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_930338"><div><strong>Autosomal dominant palmoplantar keratoderma and congenital alopecia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>930338</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4304669</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Palmoplantar keratoderma and congenital alopecia-1 (PPKCA1) is a rare autosomal dominant disorder characterized by severe hyperkeratosis and congenital alopecia. Nail changes occur in some patients (summary by Castori et al., 2010). Also see PPKCA2 (212360), an autosomal recessive disorder characterized by congenital alopecia and progressive hyperkeratosis resulting in sclerodactyly, severe contractures and tapering of the digits, and pseudoainhum formation.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/930338">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1380593"><div><strong>Erythrokeratodermia variabilis et progressiva 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1380593</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4479619</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Erythrokeratodermia variabilis et progressiva is a rare skin disease. Patients with EKVP3 have normal skin at birth but develop hyperpigmentation and scaling at sites of friction in childhood, with progression to near-confluent corrugated hyperkeratosis, palmoplantar keratoderma, and transient figurate erythema (summary by Boyden et al., 2015). For a discussion of genetic heterogeneity of EKVP, see EKVP1 (133200).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1380593">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1647369"><div><strong>Heimler syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1647369</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551980</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Heimler syndrome-1 (HMLR1), which represents the mildest end of the peroxisomal biogenesis disorder spectrum (see PBD1A, 214100), is a rare autosomal recessive disorder characterized by sensorineural hearing loss, enamel hyoplasia of the secondary dentition, and nail abnormalities (Ratbi et al., 2015). Genetic Heterogeneity of Heimler Syndrome Another form of Heimler syndrome (HMLR2; 616617) is caused by mutation in the PEX6 gene (601498) on chromosome 6p21.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1647369">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1852819"><div><strong>Ichthyosis with erythrokeratoderma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1852819</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882691</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Ichthyosis with erythrokeratoderma (IEKD) is an autosomal dominant disorder of cornification characterized by abnormal desquamation in addition to erythematous hyperkeratotic plaques or patches. Lesions are present at birth or appear soon after (Gong et al., 2023; Takeichi et al., 2023).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1852819">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_82666" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Atrophoderma vermiculatum</a></div>
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||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_930338" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal dominant palmoplantar keratoderma and congenital alopecia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_371355" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal recessive congenital ichthyosis 4A</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_862830" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cardiomyopathy, dilated, with wooly hair, keratoderma, and tooth agenesis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1380593" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Erythrokeratodermia variabilis et progressiva 3</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (15)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1647369" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Heimler syndrome 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_903520" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Heimler syndrome 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_442697" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary hypotrichosis with recurrent skin vesicles</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_75686" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hooft disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1852819" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ichthyosis with erythrokeratoderma</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_82727" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Knuckle pads, deafness AND leukonychia syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_107463" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Nonsyndromic congenital nail disorder 3</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_902464" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Peeling skin-leukonuchia-acral punctate keratoses-cheilitis-knuckle pads syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_140929" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Trichorhinophalangeal dysplasia type I</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_863639" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Wooly hair-palmoplantar keratoderma syndrome</a></div></span></div></div>
|
||
</div>
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||
<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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||
<div class="nl"><a target="_blank" href="/pubmed/36539135">SYMPTOMATOLOGY AND TREATMENT OF COVID-19 AFFECTING SKIN APPENDAGES: A NARRATIVE REVIEW BEYOND COVID-TOES.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Wollina U,
|
||
Abdelmaksoud A,
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||
Chiriac A,
|
||
Brzezinski P,
|
||
Temiz S</span><br />
|
||
<span class="medgenPMjournal">Georgian Med News</span>
|
||
2022 Oct;(331):78-84.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36539135" target="_blank">36539135</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19391293">Fungal nail infections: diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMjournal">Prescrire Int</span>
|
||
2009 Feb;18(99):26-30.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19391293" target="_blank">19391293</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22leukonychia%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (2)</a></div></div>
|
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</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
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to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
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<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38759225">Multiple Onychopapillomas and BAP1 Tumor Predisposition Syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lebensohn A,
|
||
Ghafoor A,
|
||
Bloomquist L,
|
||
Royer MC,
|
||
Castelo-Soccio L,
|
||
Karacki K,
|
||
Hathaway O,
|
||
Maglo T,
|
||
Wagner C,
|
||
Agra MG,
|
||
Blakely AM,
|
||
Schrump DS,
|
||
Hassan R,
|
||
Cowen EW</span><br />
|
||
<span class="medgenPMjournal">JAMA Dermatol</span>
|
||
2024 Aug 1;160(8):838-845.
|
||
doi: 10.1001/jamadermatol.2024.1804.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38759225" target="_blank">38759225</a><a href="/pmc/articles/PMC11102040" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35697407">Nail Psoriasis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Canal-García E,
|
||
Bosch-Amate X,
|
||
Belinchón I,
|
||
Puig L</span><br />
|
||
<span class="medgenPMjournal">Actas Dermosifiliogr</span>
|
||
2022 May;113(5):481-490.
|
||
Epub 2022 Feb 2
|
||
doi: 10.1016/j.ad.2022.01.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35697407" target="_blank">35697407</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35181410">Nail involvement in autosomal recessive congenital ichthyosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zaouak A,
|
||
Chamli A,
|
||
Ben Mansour N,
|
||
Jouini W,
|
||
Fenniche S,
|
||
Hammami H</span><br />
|
||
<span class="medgenPMjournal">Clin Dermatol</span>
|
||
2022 Jul-Aug;40(4):388-394.
|
||
Epub 2022 Feb 15
|
||
doi: 10.1016/j.clindermatol.2022.02.012.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35181410" target="_blank">35181410</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25828714">Diagnosis using nail matrix.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Richert B,
|
||
Caucanas M,
|
||
André J</span><br />
|
||
<span class="medgenPMjournal">Dermatol Clin</span>
|
||
2015 Apr;33(2):243-55.
|
||
Epub 2015 Feb 21
|
||
doi: 10.1016/j.det.2014.12.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25828714" target="_blank">25828714</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20347658">Other fungi causing onychomycosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moreno G,
|
||
Arenas R</span><br />
|
||
<span class="medgenPMjournal">Clin Dermatol</span>
|
||
2010 Mar 4;28(2):160-3.
|
||
doi: 10.1016/j.clindermatol.2009.12.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20347658" target="_blank">20347658</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Leukonychia%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (37)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35697407">Nail Psoriasis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Canal-García E,
|
||
Bosch-Amate X,
|
||
Belinchón I,
|
||
Puig L</span><br />
|
||
<span class="medgenPMjournal">Actas Dermosifiliogr</span>
|
||
2022 May;113(5):481-490.
|
||
Epub 2022 Feb 2
|
||
doi: 10.1016/j.ad.2022.01.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35697407" target="_blank">35697407</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35112320">Leukonychia: What Can White Nails Tell Us?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Iorizzo M,
|
||
Starace M,
|
||
Pasch MC</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Dermatol</span>
|
||
2022 Mar;23(2):177-193.
|
||
Epub 2022 Feb 2
|
||
doi: 10.1007/s40257-022-00671-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35112320" target="_blank">35112320</a><a href="/pmc/articles/PMC8809498" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34478047">Challenge of Nail Psoriasis: An Update Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ji C,
|
||
Wang H,
|
||
Bao C,
|
||
Zhang L,
|
||
Ruan S,
|
||
Zhang J,
|
||
Gong T,
|
||
Cheng B</span><br />
|
||
<span class="medgenPMjournal">Clin Rev Allergy Immunol</span>
|
||
2021 Dec;61(3):377-402.
|
||
Epub 2021 Sep 3
|
||
doi: 10.1007/s12016-021-08896-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34478047" target="_blank">34478047</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15450905">Nail dystrophies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bodman MA</span><br />
|
||
<span class="medgenPMjournal">Clin Podiatr Med Surg</span>
|
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2004 Oct;21(4):663-87, viii.
|
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doi: 10.1016/j.cpm.2004.05.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15450905" target="_blank">15450905</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7600507">Miscellaneous nail presentations.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bodman MA</span><br />
|
||
<span class="medgenPMjournal">Clin Podiatr Med Surg</span>
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1995 Apr;12(2):327-46.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7600507" target="_blank">7600507</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Leukonychia%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (90)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36851881">Onychomycosis Presenting as Longitudinal Leukonychia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Conway J,
|
||
Lipner SR</span><br />
|
||
<span class="medgenPMjournal">J Cutan Med Surg</span>
|
||
2023 May-Jun;27(3):298.
|
||
Epub 2023 Feb 27
|
||
doi: 10.1177/12034754231159598.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36851881" target="_blank">36851881</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20347658">Other fungi causing onychomycosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moreno G,
|
||
Arenas R</span><br />
|
||
<span class="medgenPMjournal">Clin Dermatol</span>
|
||
2010 Mar 4;28(2):160-3.
|
||
doi: 10.1016/j.clindermatol.2009.12.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20347658" target="_blank">20347658</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15257962">Chemotherapy-induced leukonychia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Benatti C,
|
||
Gnocchi M,
|
||
Travaglino E,
|
||
Invernizzi R,
|
||
Ascari E</span><br />
|
||
<span class="medgenPMjournal">Haematologica</span>
|
||
2004 Jul;89(7):EIM16.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15257962" target="_blank">15257962</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1451320">Leukonychia due to cytostatic agents.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Unamuno P,
|
||
Fernández-López E,
|
||
Santos C</span><br />
|
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<span class="medgenPMjournal">Clin Exp Dermatol</span>
|
||
1992 Jul;17(4):273-4.
|
||
doi: 10.1111/j.1365-2230.1992.tb02166.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1451320" target="_blank">1451320</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1862030">Transverse striate leukonychia associated with cancer chemotherapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hogan PA,
|
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Krafchik BR,
|
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Boxall L</span><br />
|
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<span class="medgenPMjournal">Pediatr Dermatol</span>
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1991 Mar;8(1):67-8.
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doi: 10.1111/j.1525-1470.1991.tb00845.x.
|
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<span class="bold">PMID: </span><a href="/pubmed/1862030" target="_blank">1862030</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Leukonychia%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (47)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38426318">Nail involvement in connective tissue diseases: an epidemiological, clinical, and dermoscopic study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ghannem A,
|
||
Zaouak A,
|
||
Aydi Z,
|
||
Somai M,
|
||
Hammami H,
|
||
Boussema F,
|
||
Fenniche S</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2024 Jul;63(7):942-946.
|
||
Epub 2024 Mar 1
|
||
doi: 10.1111/ijd.17113.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38426318" target="_blank">38426318</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36539135">SYMPTOMATOLOGY AND TREATMENT OF COVID-19 AFFECTING SKIN APPENDAGES: A NARRATIVE REVIEW BEYOND COVID-TOES.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wollina U,
|
||
Abdelmaksoud A,
|
||
Chiriac A,
|
||
Brzezinski P,
|
||
Temiz S</span><br />
|
||
<span class="medgenPMjournal">Georgian Med News</span>
|
||
2022 Oct;(331):78-84.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36539135" target="_blank">36539135</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29318582">Nail changes in alopecia areata: an update and review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chelidze K,
|
||
Lipner SR</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2018 Jul;57(7):776-783.
|
||
Epub 2018 Jan 10
|
||
doi: 10.1111/ijd.13866.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29318582" target="_blank">29318582</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16551786">Transverse leukonychia and AIDS.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Carvalho VO,
|
||
da Cruz CR,
|
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Marinoni LP,
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Lima JH</span><br />
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<span class="medgenPMjournal">Arch Dis Child</span>
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2006 Apr;91(4):326.
|
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doi: 10.1136/adc.2005.083030.
|
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<span class="bold">PMID: </span><a href="/pubmed/16551786" target="_blank">16551786</a><a href="/pmc/articles/PMC2065967" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/14965801">Transverse leukonychia in severe hypocalcemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Foti C,
|
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Cassano N,
|
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Palmieri VO,
|
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Portincasa P,
|
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Conserva A,
|
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Lamuraglia M,
|
||
Palasciano G,
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Vena GA</span><br />
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<span class="medgenPMjournal">Eur J Dermatol</span>
|
||
2004 Jan-Feb;14(1):67-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/14965801" target="_blank">14965801</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Leukonychia%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34396563">Clinical and onychoscopic features of histopathologically proven onychopapillomas and literature update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Starace M,
|
||
Alessandrini A,
|
||
Ferrari T,
|
||
Wong V,
|
||
Baraldi C,
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||
Piraccini BM</span><br />
|
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<span class="medgenPMjournal">J Cutan Pathol</span>
|
||
2022 Feb;49(2):147-152.
|
||
Epub 2021 Aug 30
|
||
doi: 10.1111/cup.14119.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34396563" target="_blank">34396563</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25168385">Exome sequencing reveals mutation in GJA1 as a cause of keratoderma-hypotrichosis-leukonychia totalis syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang H,
|
||
Cao X,
|
||
Lin Z,
|
||
Lee M,
|
||
Jia X,
|
||
Ren Y,
|
||
Dai L,
|
||
Guan L,
|
||
Zhang J,
|
||
Lin X,
|
||
Zhang J,
|
||
Chen Q,
|
||
Feng C,
|
||
Zhou EY,
|
||
Yin J,
|
||
Xu G,
|
||
Yang Y</span><br />
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||
<span class="medgenPMjournal">Hum Mol Genet</span>
|
||
2015 Jan 1;24(1):243-50.
|
||
Epub 2014 Aug 28
|
||
doi: 10.1093/hmg/ddu442.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25168385" target="_blank">25168385</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21665001">Hereditary leukonychia, or porcelain nails, resulting from mutations in PLCD1.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kiuru M,
|
||
Kurban M,
|
||
Itoh M,
|
||
Petukhova L,
|
||
Shimomura Y,
|
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Wajid M,
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Christiano AM</span><br />
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<span class="medgenPMjournal">Am J Hum Genet</span>
|
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2011 Jun 10;88(6):839-844.
|
||
doi: 10.1016/j.ajhg.2011.05.014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21665001" target="_blank">21665001</a><a href="/pmc/articles/PMC3113240" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20347658">Other fungi causing onychomycosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moreno G,
|
||
Arenas R</span><br />
|
||
<span class="medgenPMjournal">Clin Dermatol</span>
|
||
2010 Mar 4;28(2):160-3.
|
||
doi: 10.1016/j.clindermatol.2009.12.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20347658" target="_blank">20347658</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16092325">Transverse leukonychia: a case report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Modesto dos Santos V,
|
||
Sugai TA,
|
||
Cezar BF,
|
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Vasconcellos de Rezende AC</span><br />
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<span class="medgenPMjournal">West Afr J Med</span>
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2005 Apr-Jun;24(2):181-2.
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||
doi: 10.4314/wajm.v24i2.28194.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16092325" target="_blank">16092325</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Leukonychia%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (38)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38520074">Dermoscopic features of nail psoriasis: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rachadi H,
|
||
Chiheb S</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2024 Aug;63(8):1013-1019.
|
||
Epub 2024 Mar 22
|
||
doi: 10.1111/ijd.17138.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38520074" target="_blank">38520074</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Leukonychia%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
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|
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|
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</div>
|
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</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
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<div class="portlet mgSection" id="ID_113">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln"><ul id="my-toc"></ul></div>
|
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|
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|
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<div class="portlet mgSection" id="ID_119">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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