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<meta name="keywords" content="C0231688, finding, gait, shuffling, shuffled walk, shuffling gait, shuffling gaits, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A type of gait (walking) characterized by by dragging one's feet along or without lifting the feet fully from the ground." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=68545
|
||
ConceptID=C0231688
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-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Shuffling gait</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>68545</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0231688</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Gait, Shuffling; Shuffling Gait; Shuffling Gaits</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Shuffling gait (43005009)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0002362">HP:0002362</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A type of gait (walking) characterized by by dragging one's feet along or without lifting the feet fully from the ground. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0231688[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=68545">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=68545" ref="ncbi_uid=68545">V</a></span></span><span class="TLline">Shuffling gait</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/19974" ref="tree=MeSH" title="MedGen record for Clinical finding">Clinical finding</a></span><ul><li><span class="TLline"><a href="/medgen/272632" ref="tree=MeSH" title="MedGen record for Finding by Site or System">Finding by Site or System</a></span><ul><li><span class="TLline"><a href="/medgen/98386" ref="tree=MeSH" title="MedGen record for Neurological finding">Neurological finding</a></span><ul><li><span class="TLline"><a href="/medgen/66714" ref="tree=MeSH" title="MedGen record for Neurological symptom">Neurological symptom</a></span><ul><li><span class="TLline"><a href="/medgen/233196" ref="tree=MeSH" title="MedGen record for Motor Manifestations">Motor Manifestations</a></span><ul><li><span class="TLline"><a href="/medgen/107895" ref="tree=MeSH" title="MedGen record for Gait disturbance">Gait disturbance</a></span><ul><li><span class="matched_ds">Shuffling gait</span><ul><li><span class="TLline"><a href="/medgen/812045" ref="tree=MeSH" title="MedGen record for Short stepped shuffling gait">Short stepped shuffling gait</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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||
</div>
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||
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<div class="portlet mgSection" id="ID_112">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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||
<div class="divPopper rprt" id="rdis_162894"><div><strong>MASA syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>162894</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0795953</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">L1 syndrome involves a phenotypic spectrum ranging from severe to mild and includes three clinical phenotypes: X-linked hydrocephalus with stenosis of the aqueduct of Sylvius (HSAS). MASA (mental retardation [intellectual disability], aphasia [delayed speech], spastic paraplegia [shuffling gait], adducted thumbs) syndrome including X-linked complicated hereditary spastic paraplegia type 1. X-linked complicated corpus callosum agenesis. Males with HSAS are born with severe hydrocephalus, adducted thumbs, and spasticity; intellectual disability is severe. In less severely affected males, hydrocephalus may be subclinically present and documented only because of developmental delay; intellectual disability ranges from mild (IQ: 50-70) to moderate (IQ: 30-50). It is important to note that all phenotypes can be observed in affected individuals within the same family.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/162894">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_208674"><div><strong>Early-onset parkinsonism-intellectual disability syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>208674</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0796195</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Waisman syndrome (WSMN) is an X-linked neurologic disorder characterized by delayed psychomotor development, impaired intellectual development, and early-onset Parkinson disease (summary by Wilson et al., 2014).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/208674">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_163232"><div><strong>X-linked intellectual disability-psychosis-macroorchidism syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>163232</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0796222</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The spectrum of MECP2-related phenotypes in females ranges from classic Rett syndrome to variant Rett syndrome with a broader clinical phenotype (either milder or more severe than classic Rett syndrome) to mild learning disabilities; the spectrum in males ranges from severe neonatal encephalopathy to pyramidal signs, parkinsonism, and macroorchidism (PPM-X) syndrome to severe syndromic/nonsyndromic intellectual disability. Females: Classic Rett syndrome, a progressive neurodevelopmental disorder primarily affecting girls, is characterized by apparently normal psychomotor development during the first six to 18 months of life, followed by a short period of developmental stagnation, then rapid regression in language and motor skills, followed by long-term stability. During the phase of rapid regression, repetitive, stereotypic hand movements replace purposeful hand use. Additional findings include fits of screaming and inconsolable crying, autistic features, panic-like attacks, bruxism, episodic apnea and/or hyperpnea, gait ataxia and apraxia, tremors, seizures, and acquired microcephaly. Males: Severe neonatal-onset encephalopathy, the most common phenotype in affected males, is characterized by a relentless clinical course that follows a metabolic-degenerative type of pattern, abnormal tone, involuntary movements, severe seizures, and breathing abnormalities. Death often occurs before age two years.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/163232">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_335139"><div><strong>Syndromic X-linked intellectual disability Claes-Jensen type</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>335139</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1845243</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Claes-Jensen type of X-linked syndromic intellectual developmental disorder (MRXSCJ) is characterized by impaired intellectual development with substantial clinical heterogeneity in affected males. However, males are usually reported to have short stature, microcephaly, hyperreflexia, and aggressive behavior. In rare cases, female carriers exhibit mildly impaired intellectual development or learning difficulties (summary by Guerra et al., 2020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/335139">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_375796"><div><strong>Hereditary spastic paraplegia 16</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>375796</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1846046</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Spastic paraplegias (SPGs) are a genetically heterogeneous group of neurologic disorders characterized by progressive weakness and spasticity of the legs. Complicated SPGs are accompanied by additional neurologic symptoms such as cerebellar ataxia, sensory loss, mental retardation, nystagmus, and optic atrophy (summary by Steinmuller et al., 1997). A locus for spastic paraplegia-16 has been mapped to Xq11.2-q23 (Steinmuller et al., 1997). For a discussion of genetic heterogeneity of X-linked spastic paraplegia, see 303350.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/375796">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_357008"><div><strong>Autosomal dominant Parkinson disease 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>357008</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1868595</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Parkinson disease is the second most common neurogenic disorder after Alzheimer disease (AD; 104300), affecting approximately 1% of the population over age 50. Clinical manifestations include resting tremor, muscular rigidity, bradykinesia, and postural instability. Additional features are characteristic postural abnormalities, dysautonomia, dystonic cramps, and dementia (Polymeropoulos et al., 1996). For a general phenotypic description and a discussion of genetic heterogeneity of Parkinson disease, see 168600.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/357008">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_401500"><div><strong>Autosomal recessive juvenile Parkinson disease 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>401500</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1868675</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Parkin type of early-onset Parkinson disease (PARK-Parkin) is characterized by the cardinal signs of Parkinson disease (PD): bradykinesia, resting tremor, and rigidity. The median age at onset is 31 years (range: 3-81 years). The disease is slowly progressive: disease duration of more than 50 years has been reported. Clinical findings vary; hyperreflexia is common. Lower-limb dystonia may be a presenting sign and cognitive decline appears to be no more frequent than in the general population. Dyskinesia as a result of treatment with levodopa frequently occurs.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/401500">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_816141"><div><strong>Juvenile onset Parkinson disease 19A</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>816141</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3809811</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">DNAJC6 Parkinson disease is a complex early-onset neurologic disorder whose core features are typical parkinsonian symptoms including bradykinesia, resting tremor, rigidity, and postural instability. The majority of individuals have juvenile onset and develop symptoms before age 21 years. Developmental delay, intellectual disability, seizures, other movement disorders (e.g., dystonia, spasticity, myoclonus), and neuropsychiatric features occur in the majority of individuals with juvenile onset and often precede parkinsonism. The onset of parkinsonian features usually occurs toward the end of the first or beginning of the second decade and the disease course is rapidly progressive with loss of ambulation in mid-adolescence in the majority of individuals. Additional features include gastrointestinal manifestations and bulbar dysfunction. A minority of individuals with DNAJC6 Parkinson disease develop early-onset parkinsonism with symptom onset in the third to fourth decade and absence of additional neurologic features.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/816141">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_816154"><div><strong>Early-onset Parkinson disease 20</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>816154</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3809824</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Parkinson disease-20 is an autosomal recessive neurodegenerative disorder characterized by young adult-onset of parkinsonism. Additional features may include seizures, cognitive decline, abnormal eye movements, and dystonia (summary by Krebs et al., 2013 and Quadri et al., 2013). For a phenotypic description and a discussion of genetic heterogeneity of Parkinson disease, see PD (168600).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/816154">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_929215"><div><strong>Brain dopamine-serotonin vesicular transport disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>929215</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4303546</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An infantile-onset neurometabolic disease with characteristics of dystonia, parkinsonism, nonambulation, autonomic dysfunction, developmental delay and mood disturbances. The prevalence is unknown. It has been described in 8 patients from one Saudi Arabian family to date. Caused by a mutation in the SLC18A2 gene (10q25), encoding the vesicular monoamine transporter 2 (VMAT2) which is responsible for the transport of dopamine and serotonin into synaptic vesicles. Mutations in this gene lead to the impairment of VMAT2 and consequently to problems with motor control, autonomic functioning and mood regulation. It is inherited in an autosomal recessive manner.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/929215">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1631337"><div><strong>Leukodystrophy, hypomyelinating, 16</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1631337</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4693779</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hypomyelinating leukodystrophy-16 (HLD16) is an autosomal dominant neurologic disorder characterized by onset of hypotonia, nystagmus, and mildly delayed motor development in infancy. Affected individuals have motor disabilities, including ataxic or broad-based gait, hyperreflexia, intention tremor, dysmetria, and a mild pyramidal syndrome. Some patients have cognitive impairment, whereas others may have normal cognition or mild intellectual disability with speech difficulties. Brain imaging typically shows hypomyelination, leukodystrophy, and thin corpus callosum (summary by Simons et al., 2017). For a general phenotypic description and a discussion of genetic heterogeneity of hypomyelinating leukodystrophy, see 312080.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1631337">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1794139"><div><strong>Leukoencephalopathy, diffuse hereditary, with spheroids 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1794139</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5561929</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The spectrum of CSF1R-related disorder ranges from early-onset disease (age <18 years) to late-onset disease (age =18 years). Early-onset disease is associated with hypotonia, delayed acquisition of developmental milestones, and non-neurologic manifestations (such as skeletal abnormalities); both early- and late-onset disease have similar neurodegenerative involvement. Most affected individuals eventually become bedridden with spasticity, rigidity, and loss of the ability to walk. They lose speech and voluntary movement and appear to be generally unaware of their surroundings. The last stage of disease progresses to a vegetative state with presence of primitive reflexes, such as visual and tactile grasp, mouth-opening reflex, and sucking reflex. Death most commonly results from pneumonia or other infections. About 500 individuals with CSF1R-related disorder have been reported to date.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1794139">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1857802"><div><strong>Neurodevelopmental disorder with early-onset parkinsonism and behavioral abnormalities</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1857802</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5935590</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Neurodevelopmental disorder with early-onset parkinsonism and behavioral abnormalities (NEDPBA) is an autosomal recessive disorder characterized by delayed developmental milestones apparent in late infancy or early childhood, impaired intellectual development with learning difficulties, and behavioral abnormalities. Motor abnormalities, including parkinsonism and spasticity, usually develop in the third or fourth decades, although earlier onset has been reported. Some patients have seizures. There is inter- and intrafamilial variability (Kuipers et al., 2018; Al-Kasbi et al., 2021).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1857802">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_357008" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal dominant Parkinson disease 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_401500" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal recessive juvenile Parkinson disease 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_929215" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Brain dopamine-serotonin vesicular transport disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_816154" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Early-onset Parkinson disease 20</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_208674" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Early-onset parkinsonism-intellectual disability syndrome</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (13)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_375796" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary spastic paraplegia 16</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_816141" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Juvenile onset Parkinson disease 19A</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1631337" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Leukodystrophy, hypomyelinating, 16</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1794139" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Leukoencephalopathy, diffuse hereditary, with spheroids 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_162894" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">MASA syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1857802" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neurodevelopmental disorder with early-onset parkinsonism and behavioral abnormalities</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_335139" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Syndromic X-linked intellectual disability Claes-Jensen type</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_163232" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">X-linked intellectual disability-psychosis-macroorchidism syndrome</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39419777">Drug-induced parkinsonism: diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Conn H,
|
||
Jankovic J</span><br />
|
||
<span class="medgenPMjournal">Expert Opin Drug Saf</span>
|
||
2024 Dec;23(12):1503-1513.
|
||
Epub 2024 Oct 25
|
||
doi: 10.1080/14740338.2024.2418950.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39419777" target="_blank">39419777</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25528921">Dysfunctions associated with dementia and their treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Malak R,
|
||
Kostiukow A,
|
||
Krawczyk-Wasielewska A,
|
||
Keczmer P,
|
||
Mojs E,
|
||
Głodowska K,
|
||
Samborski W</span><br />
|
||
<span class="medgenPMjournal">Ann Agric Environ Med</span>
|
||
2014;21(4):790-1.
|
||
doi: 10.5604/12321966.1129934.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25528921" target="_blank">25528921</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15197700">Clinicopathological investigation of vascular parkinsonism, including clinical criteria for diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zijlmans JC,
|
||
Daniel SE,
|
||
Hughes AJ,
|
||
Révész T,
|
||
Lees AJ</span><br />
|
||
<span class="medgenPMjournal">Mov Disord</span>
|
||
2004 Jun;19(6):630-40.
|
||
doi: 10.1002/mds.20083.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15197700" target="_blank">15197700</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22shuffling%20gait%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (4)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39419777">Drug-induced parkinsonism: diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Conn H,
|
||
Jankovic J</span><br />
|
||
<span class="medgenPMjournal">Expert Opin Drug Saf</span>
|
||
2024 Dec;23(12):1503-1513.
|
||
Epub 2024 Oct 25
|
||
doi: 10.1080/14740338.2024.2418950.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39419777" target="_blank">39419777</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38438818">Symptoms and signs did not predict outcome after surgery: a prospective study of 143 patients with idiopathic normal pressure hydrocephalus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Andrén K,
|
||
Wikkelsø C,
|
||
Laurell K,
|
||
Kollén L,
|
||
Hellström P,
|
||
Tullberg M</span><br />
|
||
<span class="medgenPMjournal">J Neurol</span>
|
||
2024 Jun;271(6):3215-3226.
|
||
Epub 2024 Mar 5
|
||
doi: 10.1007/s00415-024-12248-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38438818" target="_blank">38438818</a><a href="/pmc/articles/PMC11136756" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36775676">With life there is motion. Activity biomarkers signal important health and performance outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Friedl KE,
|
||
Looney DP</span><br />
|
||
<span class="medgenPMjournal">J Sci Med Sport</span>
|
||
2023 Jun;26 Suppl 1:S3-S8.
|
||
Epub 2023 Feb 3
|
||
doi: 10.1016/j.jsams.2023.01.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36775676" target="_blank">36775676</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29953178">Parkinson’s Disease: Basic knowledge.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rose O</span><br />
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2016 Jul;39(7):277-81.
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<span class="bold">PMID: </span><a href="/pubmed/29953178" target="_blank">29953178</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/18344392">Parkinson's disease: clinical features and diagnosis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Jankovic J</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/18344392" target="_blank">18344392</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Shuffling%20gait%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (23)</a></div><h3 class="subhead">Diagnosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/39419777">Drug-induced parkinsonism: diagnosis and treatment.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Conn H,
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Jankovic J</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/39419777" target="_blank">39419777</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/34334283">Sporadic Creutzfeldt-Jakob disease.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Salehi P,
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Clark M,
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Pinzon J,
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Patil A</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/34334283" target="_blank">34334283</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/29953178">Parkinson’s Disease: Basic knowledge.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Rose O</span><br />
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<span class="medgenPMjournal">Med Monatsschr Pharm</span>
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2016 Jul;39(7):277-81.
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<span class="bold">PMID: </span><a href="/pubmed/29953178" target="_blank">29953178</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/25059014">Syndromes presenting adducted thumb with/without clubfoot and Dundar syndrome.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Uzak AS,
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Fryns JP,
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Dundar M</span><br />
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2014;25(2):159-69.
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<span class="bold">PMID: </span><a href="/pubmed/25059014" target="_blank">25059014</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/18344392">Parkinson's disease: clinical features and diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jankovic J</span><br />
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<span class="medgenPMjournal">J Neurol Neurosurg Psychiatry</span>
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2008 Apr;79(4):368-76.
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doi: 10.1136/jnnp.2007.131045.
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<span class="bold">PMID: </span><a href="/pubmed/18344392" target="_blank">18344392</a></div>
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||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Shuffling%20gait%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (59)</a></div><h3 class="subhead">Therapy</h3>
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||
<div class="nl"><a target="_blank" href="/pubmed/39419777">Drug-induced parkinsonism: diagnosis and treatment.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Conn H,
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Jankovic J</span><br />
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<span class="medgenPMjournal">Expert Opin Drug Saf</span>
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2024 Dec;23(12):1503-1513.
|
||
Epub 2024 Oct 25
|
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doi: 10.1080/14740338.2024.2418950.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39419777" target="_blank">39419777</a></div>
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||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35718278">Neuroprotective approaches to halt Parkinson's disease progression.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Sola P,
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Krishnamurthy PT,
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Kumari M,
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Byran G,
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Gangadharappa HV,
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Garikapati KK</span><br />
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<span class="medgenPMjournal">Neurochem Int</span>
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2022 Sep;158:105380.
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Epub 2022 Jun 17
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doi: 10.1016/j.neuint.2022.105380.
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<span class="bold">PMID: </span><a href="/pubmed/35718278" target="_blank">35718278</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/31039230">Aquatic antagonists: stingray injury update.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Rensch GP,
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Elston DM</span><br />
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<span class="medgenPMjournal">Cutis</span>
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2019 Mar;103(3):138-140.
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<span class="bold">PMID: </span><a href="/pubmed/31039230" target="_blank">31039230</a></div>
|
||
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||
<div class="nl"><a target="_blank" href="/pubmed/29953178">Parkinson’s Disease: Basic knowledge.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rose O</span><br />
|
||
<span class="medgenPMjournal">Med Monatsschr Pharm</span>
|
||
2016 Jul;39(7):277-81.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29953178" target="_blank">29953178</a></div>
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||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27379905">A potential case of remission of Parkinson's disease.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Smart K,
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Durso R,
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Morgan J,
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McNamara P</span><br />
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<span class="medgenPMjournal">J Complement Integr Med</span>
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2016 Sep 1;13(3):311-315.
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<span class="bold">PMID: </span><a href="/pubmed/27379905" target="_blank">27379905</a></div>
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||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Shuffling%20gait%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38438818">Symptoms and signs did not predict outcome after surgery: a prospective study of 143 patients with idiopathic normal pressure hydrocephalus.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Andrén K,
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Wikkelsø C,
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Laurell K,
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Kollén L,
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Hellström P,
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Tullberg M</span><br />
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<span class="medgenPMjournal">J Neurol</span>
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2024 Jun;271(6):3215-3226.
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Epub 2024 Mar 5
|
||
doi: 10.1007/s00415-024-12248-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38438818" target="_blank">38438818</a><a href="/pmc/articles/PMC11136756" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36775676">With life there is motion. Activity biomarkers signal important health and performance outcomes.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Friedl KE,
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Looney DP</span><br />
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<span class="medgenPMjournal">J Sci Med Sport</span>
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2023 Jun;26 Suppl 1:S3-S8.
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Epub 2023 Feb 3
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doi: 10.1016/j.jsams.2023.01.009.
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<span class="bold">PMID: </span><a href="/pubmed/36775676" target="_blank">36775676</a></div>
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||
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||
<div class="nl"><a target="_blank" href="/pubmed/36192179">Progressive Supranuclear Palsy Syndrome Associated With a Novel Tauopathy: Case Study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Forrest SL,
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Tartaglia MC,
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Kim A,
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Alcaide-Leon P,
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Rogaeva E,
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Lang A,
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Kovacs GG</span><br />
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<span class="medgenPMjournal">Neurology</span>
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<span class="bold">PMID: </span><a href="/pubmed/36192179" target="_blank">36192179</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/30103972">The phenotype of idiopathic normal pressure hydrocephalus-a single center study of 429 patients.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Agerskov S,
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Hellström P,
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Andrén K,
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Kollén L,
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Wikkelsö C,
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Tullberg M</span><br />
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2018 Aug 15;391:54-60.
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Epub 2018 May 30
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doi: 10.1016/j.jns.2018.05.022.
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<span class="bold">PMID: </span><a href="/pubmed/30103972" target="_blank">30103972</a></div>
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||
<div class="nl"><a target="_blank" href="/pubmed/26891472">L1 syndrome diagnosis complemented with functional analysis of L1CAM variants located to the two N-terminal Ig-like domains.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Christaller WA,
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Vos Y,
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Gebre-Medhin S,
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Hofstra RM,
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Schäfer MK</span><br />
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2017 Jan;91(1):115-120.
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Epub 2016 Mar 15
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<span class="bold">PMID: </span><a href="/pubmed/26891472" target="_blank">26891472</a></div>
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||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Shuffling%20gait%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (13)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38438818">Symptoms and signs did not predict outcome after surgery: a prospective study of 143 patients with idiopathic normal pressure hydrocephalus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Andrén K,
|
||
Wikkelsø C,
|
||
Laurell K,
|
||
Kollén L,
|
||
Hellström P,
|
||
Tullberg M</span><br />
|
||
<span class="medgenPMjournal">J Neurol</span>
|
||
2024 Jun;271(6):3215-3226.
|
||
Epub 2024 Mar 5
|
||
doi: 10.1007/s00415-024-12248-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38438818" target="_blank">38438818</a><a href="/pmc/articles/PMC11136756" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36775676">With life there is motion. Activity biomarkers signal important health and performance outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Friedl KE,
|
||
Looney DP</span><br />
|
||
<span class="medgenPMjournal">J Sci Med Sport</span>
|
||
2023 Jun;26 Suppl 1:S3-S8.
|
||
Epub 2023 Feb 3
|
||
doi: 10.1016/j.jsams.2023.01.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36775676" target="_blank">36775676</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32416898">L1CAM mutations in three fetuses diagnosed by medical exome sequencing.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li YT,
|
||
Chen JS,
|
||
Jian W,
|
||
He YD,
|
||
Li N,
|
||
Xie YN,
|
||
Wang J,
|
||
Zhang VW,
|
||
Huang WR,
|
||
Jiang FM,
|
||
Ye XQ,
|
||
Chen DJ,
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||
Chen M</span><br />
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<span class="medgenPMjournal">Taiwan J Obstet Gynecol</span>
|
||
2020 May;59(3):451-455.
|
||
doi: 10.1016/j.tjog.2020.03.022.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32416898" target="_blank">32416898</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29960101">Clinical and genetic features of L1 syndrome patients: Definition of two novel mutations.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Isik E,
|
||
Onay H,
|
||
Atik T,
|
||
Akgun B,
|
||
Cogulu O,
|
||
Ozkinay F</span><br />
|
||
<span class="medgenPMjournal">Clin Neurol Neurosurg</span>
|
||
2018 Sep;172:20-23.
|
||
Epub 2018 Jun 18
|
||
doi: 10.1016/j.clineuro.2018.06.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29960101" target="_blank">29960101</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25059014">Syndromes presenting adducted thumb with/without clubfoot and Dundar syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Uzak AS,
|
||
Fryns JP,
|
||
Dundar M</span><br />
|
||
<span class="medgenPMjournal">Genet Couns</span>
|
||
2014;25(2):159-69.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25059014" target="_blank">25059014</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Shuffling%20gait%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (25)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
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|
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|
||
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|
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|
||
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|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0231688%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0231688%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (1)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0231688%5bDISCUI%5d" target="_blank">See all (1)</a></total></li>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Shuffling%20gait" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67d5022ccde49f3df768edb6">Figure 1. [Parkinson disease: related terms in use in the clinical setting]. - G...</a>
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