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<!--
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||
UID=651
|
||
ConceptID=C0006142
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Malignant tumor of breast</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>651</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0006142</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Cancer breast; Malignant breast neoplasm</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Malignant neoplasm of breast (254837009); Malignant tumor of breast (254837009); Breast cancer (254837009); CA - Breast cancer (254837009)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help" data-jig="ncbipopper" href="#target-gene-related">Related genes:<img src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div id="target-gene-related" class="display-none">
|
||
Gene(s) associated with related conditions. For conditions<br />
|
||
in a hierarchy, the parent condition will list the genes<br />
|
||
associated with the children conditions.</div></td>
|
||
<td><a target="_blank" href="/gene/83990">BRIP1</a>, <a target="_blank" href="/gene/79728">PALB2</a>, <a target="_blank" href="/gene/11200">CHEK2</a>, <a target="_blank" href="/gene/9821">RB1CC1</a>, <a target="_blank" href="/gene/8493">PPM1D</a>, <a target="_blank" href="/gene/8438">RAD54L</a>, <a target="_blank" href="/gene/7517">XRCC3</a>, <a target="_blank" href="/gene/7157">TP53</a>, <a target="_blank" href="/gene/6794">STK11</a>, <a target="_blank" href="/gene/5892">RAD51D</a>, <a target="_blank" href="/gene/5889">RAD51C</a>, <a target="_blank" href="/gene/5888">RAD51</a>, <a target="_blank" href="/gene/5728">PTEN</a>, <a target="_blank" href="/gene/5290">PIK3CA</a>, <a target="_blank" href="/gene/5245">PHB1</a>, <a target="_blank" href="/gene/5002">SLC67A1</a>, <a target="_blank" href="/gene/4835">NQO2</a>, <a target="_blank" href="/gene/3845">KRAS</a>, <a target="_blank" href="/gene/3161">HMMR</a>, <a target="_blank" href="/gene/2099">ESR1</a>, <a target="_blank" href="/gene/999">CDH1</a>, <a target="_blank" href="/gene/841">CASP8</a>, <a target="_blank" href="/gene/675">BRCA2</a>, <a target="_blank" href="/gene/672">BRCA1</a>, <a target="_blank" href="/gene/580">BARD1</a>, <a target="_blank" href="/gene/472">ATM</a>, <a target="_blank" href="/gene/207">AKT1</a></td></tr><tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0007254" target="_blank">MONDO:0007254</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/114480" target="_blank">114480</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Breast cancer is a disease in which certain cells in the breast become abnormal and multiply uncontrollably to form a tumor. Although breast cancer is much more common in women, this form of cancer can also develop in men. In both women and men, the most common form of breast cancer begins in cells lining the milk ducts (ductal cancer). In women, cancer can also develop in the glands that produce milk (lobular cancer). Most men have little or no lobular tissue, so lobular cancer in men is very rare. <br /><br />In its early stages, breast cancer usually does not cause pain and may exhibit no noticeable symptoms. As the cancer progresses, signs and symptoms can include a lump or thickening in or near the breast; a change in the size or shape of the breast; nipple discharge, tenderness, or retraction (turning inward); and skin irritation, dimpling, redness, or scaliness. However, these changes can occur as part of many different conditions. Having one or more of these symptoms does not mean that a person definitely has breast cancer.<br /><br />In some cases, cancerous cells can invade surrounding breast tissue. In these cases, the condition is known as invasive breast cancer. Sometimes, tumors spread to other parts of the body. If breast cancer spreads, cancerous cells most often appear in the bones, liver, lungs, or brain. Tumors that begin at one site and then spread to other areas of the body are called metastatic cancers.<br /><br />A small percentage of all breast cancers cluster in families. These cancers are described as hereditary and are associated with inherited gene mutations. Hereditary breast cancers tend to develop earlier in life than noninherited (sporadic) cases, and new (primary) tumors are more likely to develop in both breasts. [from <a title="MedlinePlus Genetics" href="https://medlineplus.gov/genetics/" class="defSource" target="_blank">MedlinePlus Genetics</a>]</div>
|
||
</div>
|
||
|
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<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1458155[DISCUI]&test_type=Clinical" ref="ncbi_uid=264172">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1458155[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=264172">R</a></span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=264172" ref="ncbi_uid=264172">V</a></span></span><span class="TLline"><a href="/medgen/264172" ref="tree=GTR&ncbi_uid=264172&link_uid=264172" title="View MedGen record for 'Breast neoplasm'">Breast neoplasm</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0858252[DISCUI]&test_type=Clinical" ref="ncbi_uid=167809">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=167809" ref="ncbi_uid=167809">V</a></span></span><span class="TLline"><a href="/medgen/167809" ref="tree=GTR&ncbi_uid=167809&link_uid=167809" title="View MedGen record for 'Breast adenocarcinoma'">Breast adenocarcinoma</a></span></li><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0006142[DISCUI]&test_type=Clinical" ref="ncbi_uid=651">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=651" target="_blank" href="/omim/114480">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=651" ref="ncbi_uid=651">V</a></span></span><span class="TLline">Malignant tumor of breast</span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0346153[DISCUI]&test_type=Clinical" ref="ncbi_uid=87542">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=87542" target="_blank" href="/omim/114480">O</a></span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/NBK1247/" ref="ncbi_uid=87542">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=87542" ref="ncbi_uid=87542">V</a></span></span><span class="TLline"><a href="/medgen/87542" ref="tree=GTR&ncbi_uid=87542&link_uid=87542" title="View MedGen record for 'Familial cancer of breast'">Familial cancer of breast</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0004135[DISCUI]&test_type=Clinical" ref="ncbi_uid=439">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=439" target="_blank" href="/omim/208900">O</a></span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/?term=(NBK1138%20OR%20NBK26468)%20AND%20gene%5Bbook%5D&showtype=onebook" ref="ncbi_uid=439">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=439" ref="ncbi_uid=439">V</a></span></span><span class="TLline"><a href="/medgen/439" ref="tree=GTR&ncbi_uid=439&link_uid=439" title="View MedGen record for 'Ataxia-telangiectasia syndrome'">Ataxia-telangiectasia syndrome</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C4016951[DISCUI]&test_type=Clinical" ref="ncbi_uid=865388">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C4016951[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=865388">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=865388" target="_blank" href="/omim/605882">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=865388" ref="ncbi_uid=865388">V</a></span></span><span class="TLline"><a href="/medgen/865388" ref="tree=GTR&ncbi_uid=865388&link_uid=865388" title="View MedGen record for 'Breast cancer, early-onset'">Breast cancer, early-onset</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1861906[DISCUI]&test_type=Clinical" ref="ncbi_uid=350535">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1861906[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=350535">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=350535" target="_blank" href="/omim/114480">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/350535" ref="tree=GTR&ncbi_uid=350535&link_uid=350535" title="View MedGen record for 'Breast cancer, familial male'">Breast cancer, familial male</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C3469522[DISCUI]&test_type=Clinical" ref="ncbi_uid=854012">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C3469522[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=854012">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=854012" target="_blank" href="/omim/176705">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=854012" ref="ncbi_uid=854012">V</a></span></span><span class="TLline"><a href="/medgen/854012" ref="tree=GTR&ncbi_uid=854012&link_uid=854012" title="View MedGen record for 'Breast cancer, susceptibility to'">Breast cancer, susceptibility to</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1836860[DISCUI]&test_type=Clinical" ref="ncbi_uid=323015">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=323015" target="_blank" href="/omim/605882">O</a></span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/NBK1401/" ref="ncbi_uid=323015">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=323015" ref="ncbi_uid=323015">V</a></span></span><span class="TLline"><a href="/medgen/323015" ref="tree=GTR&ncbi_uid=323015&link_uid=323015" title="View MedGen record for 'Fanconi anemia complementation group J'">Fanconi anemia complementation group J</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1835817[DISCUI]&test_type=Clinical" ref="ncbi_uid=372133">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=372133" target="_blank" href="/omim/610355">O</a></span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/NBK1401/" ref="ncbi_uid=372133">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=372133" ref="ncbi_uid=372133">V</a></span></span><span class="TLline"><a href="/medgen/372133" ref="tree=GTR&ncbi_uid=372133&link_uid=372133" title="View MedGen record for 'Fanconi anemia complementation group N'">Fanconi anemia complementation group N</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0677776[DISCUI]&test_type=Clinical" ref="ncbi_uid=151793">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/NBK1247/" ref="ncbi_uid=151793">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=151793" ref="ncbi_uid=151793">V</a></span></span><span class="TLline"><a href="/medgen/151793" ref="tree=GTR&ncbi_uid=151793&link_uid=151793" title="View MedGen record for 'Hereditary breast ovarian cancer syndrome'">Hereditary breast ovarian cancer syndrome</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0085390[DISCUI]&test_type=Clinical" ref="ncbi_uid=88399">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=88399" target="_blank" href="/omim/151623">O</a></span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/NBK1311/" ref="ncbi_uid=88399">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=88399" ref="ncbi_uid=88399">V</a></span></span><span class="TLline"><a href="/medgen/88399" ref="tree=GTR&ncbi_uid=88399&link_uid=88399" title="View MedGen record for 'Li-Fraumeni syndrome'">Li-Fraumeni syndrome</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0031269[DISCUI]&test_type=Clinical" ref="ncbi_uid=18404">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=18404" target="_blank" href="/omim/175200">O</a></span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/NBK1266/" ref="ncbi_uid=18404">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=18404" ref="ncbi_uid=18404">V</a></span></span><span class="TLline"><a href="/medgen/18404" ref="tree=GTR&ncbi_uid=18404&link_uid=18404" title="View MedGen record for 'Peutz-Jeghers syndrome'">Peutz-Jeghers syndrome</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1959582[DISCUI]&test_type=Clinical" ref="ncbi_uid=368366">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=368366" target="_blank" href="/omim/158350">O</a></span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/NBK1488/" ref="ncbi_uid=368366">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=368366" ref="ncbi_uid=368366">V</a></span></span><span class="TLline"><a href="/medgen/368366" ref="tree=GTR&ncbi_uid=368366&link_uid=368366" title="View MedGen record for 'PTEN hamartoma tumor syndrome'">PTEN hamartoma tumor syndrome</a></span></li></ul></li></ul></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/871338" ref="tree=MeSH" title="MedGen record for Abnormality of the breast">Abnormality of the breast</a></span><ul><li><span class="TLline"><a href="/medgen/1627648" ref="tree=MeSH" title="MedGen record for Abnormal breast morphology">Abnormal breast morphology</a></span><ul><li><span class="TLline"><a href="/medgen/264172" ref="tree=MeSH" title="MedGen record for Breast neoplasm">Breast neoplasm</a></span><ul><li><span class="matched_ds">Malignant tumor of breast</span><ul><li><span class="TLline"><a href="/medgen/146260" ref="tree=MeSH" title="MedGen record for Breast carcinoma">Breast carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/128977" ref="tree=MeSH" title="MedGen record for Bilateral breast carcinoma">Bilateral breast carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/476342" ref="tree=MeSH" title="MedGen record for Contralateral Breast Carcinoma">Contralateral Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/271163" ref="tree=MeSH" title="MedGen record for Synchronous bilateral breast carcinoma">Synchronous bilateral breast carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/167809" ref="tree=MeSH" title="MedGen record for Breast adenocarcinoma">Breast adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/272988" ref="tree=MeSH" title="MedGen record for Acinic cell breast carcinoma">Acinic cell breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/267902" ref="tree=MeSH" title="MedGen record for Breast Adenocarcinoma with Spindle Cell Metaplasia">Breast Adenocarcinoma with Spindle Cell Metaplasia</a></span></li><li><span class="TLline"><a href="/medgen/231960" ref="tree=MeSH" title="MedGen record for Breast Adenocarcinoma with Squamous Metaplasia">Breast Adenocarcinoma with Squamous Metaplasia</a></span></li><li><span class="TLline"><a href="/medgen/272319" ref="tree=MeSH" title="MedGen record for Breast apocrine carcinoma">Breast apocrine carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/770984" ref="tree=MeSH" title="MedGen record for Breast carcinoma by gene expression profile">Breast carcinoma by gene expression profile</a></span></li><li><span class="TLline"><a href="/medgen/315942" ref="tree=MeSH" title="MedGen record for Breast ductal adenocarcinoma">Breast ductal adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/64634" ref="tree=MeSH" title="MedGen record for Breast lobular carcinoma">Breast lobular carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/235337" ref="tree=MeSH" title="MedGen record for Breast mucinous carcinoma">Breast mucinous carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/267769" ref="tree=MeSH" title="MedGen record for Breast mucinous cystadenocarcinoma">Breast mucinous cystadenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/818226" ref="tree=MeSH" title="MedGen record for Breast papillary carcinoma">Breast papillary carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1792206" ref="tree=MeSH" title="MedGen record for HER2-Low Breast Carcinoma">HER2-Low Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1714400" ref="tree=MeSH" title="MedGen record for HER2-Negative Breast Carcinoma">HER2-Negative Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1713331" ref="tree=MeSH" title="MedGen record for Hormone Receptor-Negative Breast Carcinoma">Hormone Receptor-Negative Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1670518" ref="tree=MeSH" title="MedGen record for Hormone Receptor-Positive Breast Carcinoma">Hormone Receptor-Positive Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1631521" ref="tree=MeSH" title="MedGen record for Hormone-resistant breast carcinoma">Hormone-resistant breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/75841" ref="tree=MeSH" title="MedGen record for Inflammatory breast carcinoma">Inflammatory breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233580" ref="tree=MeSH" title="MedGen record for Invasive Breast Cribriform Carcinoma">Invasive Breast Cribriform Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/230969" ref="tree=MeSH" title="MedGen record for Invasive tubular breast carcinoma">Invasive tubular breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/18263" ref="tree=MeSH" title="MedGen record for Mammary Paget disease">Mammary Paget disease</a></span></li><li><span class="TLline"><a href="/medgen/1712425" ref="tree=MeSH" title="MedGen record for Metastatic Breast Adenocarcinoma">Metastatic Breast Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1779609" ref="tree=MeSH" title="MedGen record for Mixed lobular and ductal breast carcinoma">Mixed lobular and ductal breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1778672" ref="tree=MeSH" title="MedGen record for Recurrent Breast Adenocarcinoma">Recurrent Breast Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1715668" ref="tree=MeSH" title="MedGen record for Refractory Breast Adenocarcinoma">Refractory Breast Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/236816" ref="tree=MeSH" title="MedGen record for Signet ring cell breast carcinoma">Signet ring cell breast carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/455939" ref="tree=MeSH" title="MedGen record for Breast Cancer by AJCC v6 Stage">Breast Cancer by AJCC v6 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1614733" ref="tree=MeSH" title="MedGen record for Stage 0 Breast Cancer AJCC v6 and v7">Stage 0 Breast Cancer AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/75824" ref="tree=MeSH" title="MedGen record for Stage I Breast Cancer AJCC v6">Stage I Breast Cancer AJCC v6</a></span></li><li><span class="TLline"><a href="/medgen/1625688" ref="tree=MeSH" title="MedGen record for Stage II Breast Cancer AJCC v6 and v7">Stage II Breast Cancer AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/75825" ref="tree=MeSH" title="MedGen record for Stage III Breast Cancer AJCC v6">Stage III Breast Cancer AJCC v6</a></span></li><li><span class="TLline"><a href="/medgen/1615085" ref="tree=MeSH" title="MedGen record for Stage IV Breast Cancer AJCC v6 and v7">Stage IV Breast Cancer AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/456321" ref="tree=MeSH" title="MedGen record for Breast Cancer by AJCC v7 Stage">Breast Cancer by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/453226" ref="tree=MeSH" title="MedGen record for Stage I Breast Cancer AJCC v7">Stage I Breast Cancer AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/459999" ref="tree=MeSH" title="MedGen record for Stage III Breast Cancer AJCC v7">Stage III Breast Cancer AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1615855" ref="tree=MeSH" title="MedGen record for Breast Cancer by AJCC v8 Stage">Breast Cancer by AJCC v8 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1612798" ref="tree=MeSH" title="MedGen record for Breast Cancer by AJCC v8 Anatomic Stage">Breast Cancer by AJCC v8 Anatomic Stage</a></span></li><li><span class="TLline"><a href="/medgen/1615156" ref="tree=MeSH" title="MedGen record for Breast Cancer by AJCC v8 Prognostic Stage">Breast Cancer by AJCC v8 Prognostic Stage</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/68650" ref="tree=MeSH" title="MedGen record for Carcinoma of male breast">Carcinoma of male breast</a></span><ul><li><span class="TLline"><a href="/medgen/232280" ref="tree=MeSH" title="MedGen record for Hereditary Male Breast Carcinoma">Hereditary Male Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1788755" ref="tree=MeSH" title="MedGen record for Invasive Male Breast Carcinoma">Invasive Male Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/673213" ref="tree=MeSH" title="MedGen record for Male Breast Carcinoma In Situ">Male Breast Carcinoma In Situ</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/856665" ref="tree=MeSH" title="MedGen record for Childhood Breast Carcinoma">Childhood Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/458891" ref="tree=MeSH" title="MedGen record for Early Stage Breast Carcinoma">Early Stage Breast Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1793278" ref="tree=MeSH" title="MedGen record for Early Stage Triple-Negative Breast Carcinoma">Early Stage Triple-Negative Breast Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87542" ref="tree=MeSH" title="MedGen record for Familial cancer of breast">Familial cancer of breast</a></span><ul><li><span class="TLline"><a href="/medgen/439" ref="tree=MeSH" title="MedGen record for Ataxia-telangiectasia syndrome">Ataxia-telangiectasia syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1710970" ref="tree=MeSH" title="MedGen record for BRCA-Associated Breast Carcinoma">BRCA-Associated Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/865388" ref="tree=MeSH" title="MedGen record for Breast cancer, early-onset">Breast cancer, early-onset</a></span></li><li><span class="TLline"><a href="/medgen/350535" ref="tree=MeSH" title="MedGen record for Breast cancer, familial male">Breast cancer, familial male</a></span></li><li><span class="TLline"><a href="/medgen/854012" ref="tree=MeSH" title="MedGen record for Breast cancer, susceptibility to">Breast cancer, susceptibility to</a></span></li><li><span class="TLline"><a href="/medgen/323015" ref="tree=MeSH" title="MedGen record for Fanconi anemia complementation group J">Fanconi anemia complementation group J</a></span></li><li><span class="TLline"><a href="/medgen/372133" ref="tree=MeSH" title="MedGen record for Fanconi anemia complementation group N">Fanconi anemia complementation group N</a></span></li><li><span class="TLline"><a href="/medgen/151793" ref="tree=MeSH" title="MedGen record for Hereditary breast ovarian cancer syndrome">Hereditary breast ovarian cancer syndrome</a></span></li><li><span class="TLline"><a href="/medgen/272712" ref="tree=MeSH" title="MedGen record for Hereditary Female Breast Carcinoma">Hereditary Female Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/88399" ref="tree=MeSH" title="MedGen record for Li-Fraumeni syndrome">Li-Fraumeni syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1716658" ref="tree=MeSH" title="MedGen record for PALB2-Associated Breast Carcinoma">PALB2-Associated Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/18404" ref="tree=MeSH" title="MedGen record for Peutz-Jeghers syndrome">Peutz-Jeghers syndrome</a></span></li><li><span class="TLline"><a href="/medgen/368366" ref="tree=MeSH" title="MedGen record for PTEN hamartoma tumor syndrome">PTEN hamartoma tumor syndrome</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/40099" ref="tree=MeSH" title="MedGen record for Female breast carcinoma">Female breast carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/673174" ref="tree=MeSH" title="MedGen record for Female Breast Carcinoma In Situ">Female Breast Carcinoma In Situ</a></span></li><li><span class="TLline"><a href="/medgen/1781389" ref="tree=MeSH" title="MedGen record for Invasive Female Breast Carcinoma">Invasive Female Breast Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163435" ref="tree=MeSH" title="MedGen record for Invasive breast carcinoma">Invasive breast carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/231031" ref="tree=MeSH" title="MedGen record for Adenoid cystic breast carcinoma">Adenoid cystic breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/273396" ref="tree=MeSH" title="MedGen record for Breast Mixed Carcinoma">Breast Mixed Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1784659" ref="tree=MeSH" title="MedGen record for Breast Neuroendocrine Carcinoma">Breast Neuroendocrine Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/569658" ref="tree=MeSH" title="MedGen record for Breast Paget Disease with Invasive Ductal Carcinoma">Breast Paget Disease with Invasive Ductal Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1785472" ref="tree=MeSH" title="MedGen record for Breast Polymorphous Adenocarcinoma">Breast Polymorphous Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/87226" ref="tree=MeSH" title="MedGen record for Breast secretory carcinoma">Breast secretory carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1784377" ref="tree=MeSH" title="MedGen record for Breast Tall Cell Carcinoma with Reversed Polarity">Breast Tall Cell Carcinoma with Reversed Polarity</a></span></li><li><span class="TLline"><a href="/medgen/232670" ref="tree=MeSH" title="MedGen record for Invasive Breast Apocrine Carcinoma">Invasive Breast Apocrine Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233578" ref="tree=MeSH" title="MedGen record for Invasive Breast Carcinoma by Histologic Grade">Invasive Breast Carcinoma by Histologic Grade</a></span></li><li><span class="TLline"><a href="/medgen/233581" ref="tree=MeSH" title="MedGen record for Invasive Breast Papillary Carcinoma">Invasive Breast Papillary Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/75994" ref="tree=MeSH" title="MedGen record for Invasive lobular breast carcinoma">Invasive lobular breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/309375" ref="tree=MeSH" title="MedGen record for Malignant breast myoepithelioma">Malignant breast myoepithelioma</a></span></li><li><span class="TLline"><a href="/medgen/277360" ref="tree=MeSH" title="MedGen record for Metaplastic breast carcinoma">Metaplastic breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/473642" ref="tree=MeSH" title="MedGen record for Microinvasive Breast Carcinoma">Microinvasive Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233721" ref="tree=MeSH" title="MedGen record for Mucoepidermoid breast carcinoma">Mucoepidermoid breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233465" ref="tree=MeSH" title="MedGen record for Squamous cell breast carcinoma">Squamous cell breast carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1690308" ref="tree=MeSH" title="MedGen record for Localized Breast Carcinoma">Localized Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1651514" ref="tree=MeSH" title="MedGen record for Metastatic Breast Carcinoma">Metastatic Breast Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1687643" ref="tree=MeSH" title="MedGen record for Advanced Breast Carcinoma">Advanced Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/272383" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Bone">Breast Carcinoma Metastatic in the Bone</a></span></li><li><span class="TLline"><a href="/medgen/1612003" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Central Nervous System">Breast Carcinoma Metastatic in the Central Nervous System</a></span></li><li><span class="TLline"><a href="/medgen/272384" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Liver">Breast Carcinoma Metastatic in the Liver</a></span></li><li><span class="TLline"><a href="/medgen/231964" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Lung">Breast Carcinoma Metastatic in the Lung</a></span></li><li><span class="TLline"><a href="/medgen/1659340" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Lymph Nodes">Breast Carcinoma Metastatic in the Lymph Nodes</a></span></li><li><span class="TLline"><a href="/medgen/1703295" ref="tree=MeSH" title="MedGen record for Locally Advanced Breast Carcinoma">Locally Advanced Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1697431" ref="tree=MeSH" title="MedGen record for Metastatic BRCA-Associated Breast Carcinoma">Metastatic BRCA-Associated Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/182595" ref="tree=MeSH" title="MedGen record for Metastatic Breast Carcinoma in the Skin">Metastatic Breast Carcinoma in the Skin</a></span></li><li><span class="TLline"><a href="/medgen/233188" ref="tree=MeSH" title="MedGen record for Metastatic Breast Squamous Cell Carcinoma">Metastatic Breast Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1792180" ref="tree=MeSH" title="MedGen record for Oligometastatic Breast Carcinoma">Oligometastatic Breast Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/458890" ref="tree=MeSH" title="MedGen record for Multicentric Breast Carcinoma">Multicentric Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/458888" ref="tree=MeSH" title="MedGen record for Multifocal breast carcinoma">Multifocal breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233756" ref="tree=MeSH" title="MedGen record for Nipple carcinoma">Nipple carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/352830" ref="tree=MeSH" title="MedGen record for Paget disease of the nipple">Paget disease of the nipple</a></span></li><li><span class="TLline"><a href="/medgen/236845" ref="tree=MeSH" title="MedGen record for Squamous Cell Carcinoma In Situ of the Nipple">Squamous Cell Carcinoma In Situ of the Nipple</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1612883" ref="tree=MeSH" title="MedGen record for Occult Breast Carcinoma">Occult Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/75826" ref="tree=MeSH" title="MedGen record for Recurrent Breast Carcinoma">Recurrent Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1647173" ref="tree=MeSH" title="MedGen record for Refractory Breast Carcinoma">Refractory Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233463" ref="tree=MeSH" title="MedGen record for Sporadic breast cancer">Sporadic breast cancer</a></span></li><li><span class="TLline"><a href="/medgen/328143" ref="tree=MeSH" title="MedGen record for Unilateral Breast Carcinoma">Unilateral Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1702294" ref="tree=MeSH" title="MedGen record for Unresectable Breast Carcinoma">Unresectable Breast Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1698790" ref="tree=MeSH" title="MedGen record for Locally Advanced Unresectable Breast Carcinoma">Locally Advanced Unresectable Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1702632" ref="tree=MeSH" title="MedGen record for Unresectable Breast Inflammatory Carcinoma">Unresectable Breast Inflammatory Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1718900" ref="tree=MeSH" title="MedGen record for Unresectable Triple-Negative Breast Carcinoma">Unresectable Triple-Negative Breast Carcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/309939" ref="tree=MeSH" title="MedGen record for Breast lymphoma">Breast lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/277531" ref="tree=MeSH" title="MedGen record for Breast Non-Hodgkin Lymphoma">Breast Non-Hodgkin Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/267398" ref="tree=MeSH" title="MedGen record for Breast Burkitt Lymphoma">Breast Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/267764" ref="tree=MeSH" title="MedGen record for Breast diffuse large B-cell lymphoma">Breast diffuse large B-cell lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/267765" ref="tree=MeSH" title="MedGen record for Breast Follicular Lymphoma">Breast Follicular Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/234051" ref="tree=MeSH" title="MedGen record for Breast mucosa-associated lymphoid tissue lymphoma">Breast mucosa-associated lymphoid tissue lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/233348" ref="tree=MeSH" title="MedGen record for Breast T-Cell Non-Hodgkin Lymphoma">Breast T-Cell Non-Hodgkin Lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1617010" ref="tree=MeSH" title="MedGen record for Recurrent Breast Lymphoma">Recurrent Breast Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/1778761" ref="tree=MeSH" title="MedGen record for Recurrent Breast Implant-Associated Anaplastic Large Cell Lymphoma">Recurrent Breast Implant-Associated Anaplastic Large Cell Lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1627359" ref="tree=MeSH" title="MedGen record for Refractory Breast Lymphoma">Refractory Breast Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/1784135" ref="tree=MeSH" title="MedGen record for Refractory Breast Implant-Associated Anaplastic Large Cell Lymphoma">Refractory Breast Implant-Associated Anaplastic Large Cell Lymphoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/277329" ref="tree=MeSH" title="MedGen record for Breast malignant eccrine spiradenoma">Breast malignant eccrine spiradenoma</a></span></li><li><span class="TLline"><a href="/medgen/1791978" ref="tree=MeSH" title="MedGen record for Breast Periductal Stromal Tumor">Breast Periductal Stromal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/87613" ref="tree=MeSH" title="MedGen record for Breast sarcoma">Breast sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/272382" ref="tree=MeSH" title="MedGen record for Breast angiosarcoma">Breast angiosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/307996" ref="tree=MeSH" title="MedGen record for Postradiation Breast Angiosarcoma">Postradiation Breast Angiosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/928936" ref="tree=MeSH" title="MedGen record for Primary Breast Angiosarcoma">Primary Breast Angiosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1616375" ref="tree=MeSH" title="MedGen record for Recurrent Breast Angiosarcoma">Recurrent Breast Angiosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/235414" ref="tree=MeSH" title="MedGen record for Breast extraskeletal osteosarcoma">Breast extraskeletal osteosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/272385" ref="tree=MeSH" title="MedGen record for Breast fibrosarcoma">Breast fibrosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/234050" ref="tree=MeSH" title="MedGen record for Breast leiomyosarcoma">Breast leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/231968" ref="tree=MeSH" title="MedGen record for Breast liposarcoma">Breast liposarcoma</a></span></li><li><span class="TLline"><a href="/medgen/231970" ref="tree=MeSH" title="MedGen record for Breast rhabdomyosarcoma">Breast rhabdomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1736326" ref="tree=MeSH" title="MedGen record for Recurrent Breast Sarcoma">Recurrent Breast Sarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233142" ref="tree=MeSH" title="MedGen record for Malignant Breast Adenomyoepithelioma">Malignant Breast Adenomyoepithelioma</a></span></li><li><span class="TLline"><a href="/medgen/138069" ref="tree=MeSH" title="MedGen record for Malignant breast melanoma">Malignant breast melanoma</a></span></li><li><span class="TLline"><a href="/medgen/87543" ref="tree=MeSH" title="MedGen record for Malignant breast phyllodes tumor">Malignant breast phyllodes tumor</a></span></li><li><span class="TLline"><a href="/medgen/163564" ref="tree=MeSH" title="MedGen record for Malignant Nipple Neoplasm">Malignant Nipple Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/882994" ref="tree=MeSH" title="MedGen record for Female Malignant Nipple Neoplasm">Female Malignant Nipple Neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/889752" ref="tree=MeSH" title="MedGen record for Male Malignant Nipple Neoplasm">Male Malignant Nipple Neoplasm</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1737420" ref="tree=MeSH" title="MedGen record for Metastatic Malignant Breast Neoplasm">Metastatic Malignant Breast Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/1666248" ref="tree=MeSH" title="MedGen record for Metastatic Breast Neuroendocrine Neoplasm">Metastatic Breast Neuroendocrine Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/233179" ref="tree=MeSH" title="MedGen record for Metastatic Breast Neuroendocrine Tumor G1">Metastatic Breast Neuroendocrine Tumor G1</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1787931" ref="tree=MeSH" title="MedGen record for Metastatic Malignant Neoplasm in the Breast">Metastatic Malignant Neoplasm in the Breast</a></span></li><li><span class="TLline"><a href="/medgen/1721094" ref="tree=MeSH" title="MedGen record for Recurrent Malignant Breast Neoplasm">Recurrent Malignant Breast Neoplasm</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31099174">EAA clinical practice guidelines-gynecomastia evaluation and management.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Kanakis GA,
|
||
Nordkap L,
|
||
Bang AK,
|
||
Calogero AE,
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||
Bártfai G,
|
||
Corona G,
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||
Forti G,
|
||
Toppari J,
|
||
Goulis DG,
|
||
Jørgensen N</span><br />
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||
<span class="medgenPMjournal">Andrology</span>
|
||
2019 Nov;7(6):778-793.
|
||
Epub 2019 May 16
|
||
doi: 10.1111/andr.12636.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31099174" target="_blank">31099174</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22malignant%20tumor%20of%20breast%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng101" target="_blank">UK NICE Guideline NG101, Early and locally advanced breast cancer: diagnosis and management, 2024</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng12" target="_blank">UK NICE Guideline NG12, Suspected cancer: recognition and referral, 2023</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Breast Cancer, 2023</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1419" target="_blank">Breast Cancer, NCCN Guidelines Version 4.2022</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/dg34" target="_blank">Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer (DG34)</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_114">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Suggested_Reading">Suggested Reading</h1><a sid="114" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/26389258">Cancer Genetics Risk Assessment and Counseling (PDQ®): Health Professional Version.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">PDQ Cancer Genetics Editorial Board</span><br />
|
||
|
||
2002
|
||
<span class="bold">PMID: </span><a href="/pubmed/26389258" target="_blank">26389258</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26389210">Genetics of Breast and Gynecologic Cancers (PDQ®): Health Professional Version.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">PDQ Cancer Genetics Editorial Board</span><br />
|
||
|
||
2002
|
||
<span class="bold">PMID: </span><a href="/pubmed/26389210" target="_blank">26389210</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=" title="PubMed search"></a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/25651902">Comprehensive lipid profiling of plasma in patients with benign breast tumor and breast cancer reveals novel biomarkers.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yang L,
|
||
Cui X,
|
||
Zhang N,
|
||
Li M,
|
||
Bai Y,
|
||
Han X,
|
||
Shi Y,
|
||
Liu H</span><br />
|
||
<span class="medgenPMjournal">Anal Bioanal Chem</span>
|
||
2015 Jul;407(17):5065-77.
|
||
Epub 2015 Feb 5
|
||
doi: 10.1007/s00216-015-8484-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25651902" target="_blank">25651902</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Malignant%20tumor%20of%20breast%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/25651902">Comprehensive lipid profiling of plasma in patients with benign breast tumor and breast cancer reveals novel biomarkers.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yang L,
|
||
Cui X,
|
||
Zhang N,
|
||
Li M,
|
||
Bai Y,
|
||
Han X,
|
||
Shi Y,
|
||
Liu H</span><br />
|
||
<span class="medgenPMjournal">Anal Bioanal Chem</span>
|
||
2015 Jul;407(17):5065-77.
|
||
Epub 2015 Feb 5
|
||
doi: 10.1007/s00216-015-8484-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25651902" target="_blank">25651902</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Malignant%20tumor%20of%20breast%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0006142%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (3)</a></li>
|
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<li><a href="/gtr/tests?term=C0006142%5bDISCUI%5d&filter=method%3A3%5F31" target="_blank">Fluorescence in situ hybridization (FISH) (1)</a></li>
|
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<li><a href="/gtr/tests?term=C0006142%5bDISCUI%5d&filter=method%3A2%5F17" target="_blank">Mutation scanning of the entire coding region (1)</a></li>
|
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<li><a href="/gtr/tests?term=C0006142%5bDISCUI%5d&filter=method%3A2%5F30" target="_blank">RNA analysis (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0006142%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (11)</a></li>
|
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<li><a href="/gtr/tests?term=C0006142%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (3)</a></li>
|
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0006142%5bDISCUI%5d" target="_blank">See all (14)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Malignant%20tumor%20of%20breast" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22malignant%20tumor%20of%20breast%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Malignant%20tumor%20of%20breast%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng101">NICE, 2024</a><div>UK NICE Guideline NG101, Early and locally advanced breast cancer: diagnosis and management, 2024</div></li><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng12">NICE, 2023</a><div>UK NICE Guideline NG12, Suspected cancer: recognition and referral, 2023</div></li><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf">NCCN, 2023</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Breast Cancer, 2023</div></li><li><a target="_blank" href="https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1419">NCCN, 2023</a><div>Breast Cancer, NCCN Guidelines Version 4.2022</div></li><li><a target="_blank" href="https://www.nice.org.uk/guidance/dg34">NICE, 2018</a><div>Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer (DG34)</div></li></ul></div>
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