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<!--
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UID=604849
|
||
ConceptID=C0426396
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Dark urine</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>604849</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0426396</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Urine looks dark</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Urine looks dark (39575007)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0040319">HP:0040319</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">An abnormal dark color of the urine. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Dark urine</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/52948" ref="tree=MeSH" title="MedGen record for Abnormality of the genitourinary system">Abnormality of the genitourinary system</a></span><ul><li><span class="TLline"><a href="/medgen/867444" ref="tree=MeSH" title="MedGen record for Abnormality of the urinary system">Abnormality of the urinary system</a></span><ul><li><span class="TLline"><a href="/medgen/869020" ref="tree=MeSH" title="MedGen record for Abnormality of the urinary system physiology">Abnormality of the urinary system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/871178" ref="tree=MeSH" title="MedGen record for Abnormality of urine homeostasis">Abnormality of urine homeostasis</a></span><ul><li><span class="TLline"><a href="/medgen/1746789" ref="tree=MeSH" title="MedGen record for Abnormal macroscopic urine appearance">Abnormal macroscopic urine appearance</a></span><ul><li><span class="TLline"><a href="/medgen/105508" ref="tree=MeSH" title="MedGen record for Abnormal urinary color">Abnormal urinary color</a></span><ul><li><span class="matched_ds">Dark urine</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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|
||
<div class="portlet mgSection" id="ID_112">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_1413"><div><strong>Alkaptonuria</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1413</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0002066</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Alkaptonuria is caused by deficiency of homogentisate 1,2-dioxygenase, an enzyme that converts homogentisic acid (HGA) to maleylacetoacetic acid in the tyrosine degradation pathway. The three major features of alkaptonuria are dark urine or urine that turns dark on standing, ochronosis (bluish-black pigmentation in connective tissue), and arthritis of the spine and larger joints. Ochronosis generally occurs after age 30 years; arthritis often begins in the third decade. Other manifestations can include pigment in the sclera, ear cartilage, and skin of the hands; aortic or mitral valve calcification or regurgitation and occasionally aortic dilatation; renal stones; prostate stones; and hypothyroidism.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1413">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_5341"><div><strong>Glycogen storage disease, type V</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5341</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0017924</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Glycogen storage disease type V (GSDV, McArdle disease) is a metabolic myopathy characterized by exercise intolerance manifested by rapid fatigue, myalgia, and cramps in exercising muscles. Symptoms are usually precipitated by isometric exercise or sustained aerobic exercise. Most individuals improve their exercise tolerance by exploiting the "second-wind" phenomenon with relief of myalgia and fatigue after a few minutes of rest. Age of onset is frequently in the first decade of life but can vary; however, diagnosis is typically delayed as myalgia and fatigability are dismissed/overlooked. Fixed muscle weakness occurs in approximately 25% of affected individuals, is more likely to involve proximal muscles, and is more common in individuals of advanced age. Approximately 50% of affected individuals have recurrent episodes of myoglobinuria that can – on occasion – eventually result in acute renal failure.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5341">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_338045"><div><strong>Mitochondrial DNA depletion syndrome 6 (hepatocerebral type)</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>338045</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1850406</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">MPV17-related mitochondrial DNA (mtDNA) maintenance defect presents in the vast majority of affected individuals as an early-onset encephalohepatopathic (hepatocerebral) disease that is typically associated with mtDNA depletion, particularly in the liver. A later-onset neuromyopathic disease characterized by myopathy and neuropathy, and associated with multiple mtDNA deletions in muscle, has also rarely been described. MPV17-related mtDNA maintenance defect, encephalohepatopathic form is characterized by: Hepatic manifestations (liver dysfunction that typically progresses to liver failure, cholestasis, hepatomegaly, and steatosis); Neurologic involvement (developmental delay, hypotonia, microcephaly, and motor and sensory peripheral neuropathy); Gastrointestinal manifestations (gastrointestinal dysmotility, feeding difficulties, and failure to thrive); and Metabolic derangements (lactic acidosis and hypoglycemia). Less frequent manifestations include renal tubulopathy, nephrocalcinosis, and hypoparathyroidism. Progressive liver disease often leads to death in infancy or early childhood. Hepatocellular carcinoma has been reported.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/338045">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1648376"><div><strong>X-linked congenital hemolytic anemia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648376</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4746970</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1648376">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1794200"><div><strong>Biliary, renal, neurologic, and skeletal syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1794200</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5561990</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Biliary, renal, neurologic, and skeletal syndrome (BRENS) is an autosomal recessive complex ciliopathy with multisystemic manifestations. The most common presentation is severe neonatal cholestasis that progresses to liver fibrosis and cirrhosis. Most patients have additional clinical features suggestive of a ciliopathy, including postaxial polydactyly, hydrocephalus, retinal abnormalities, and situs inversus. Additional features of the syndrome may include congenital cardiac defects, echogenic kidneys with renal failure, ocular abnormalities, joint hyperextensibility, and dysmorphic facial features. Some patients have global developmental delay. Brain imaging typically shows dilated ventricles, hypomyelination, and white matter abnormalities, although some patients have been described with abnormal pituitary development (summary by Shaheen et al., 2020 and David et al., 2020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1794200">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1413" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Alkaptonuria</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1794200" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Biliary, renal, neurologic, and skeletal syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_5341" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease, type V</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_338045" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mitochondrial DNA depletion syndrome 6 (hepatocerebral type)</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648376" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">X-linked congenital hemolytic anemia</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28235546">Non-traumatic rhabdomyolysis: Background, laboratory features, and acute clinical management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cervellin G,
|
||
Comelli I,
|
||
Benatti M,
|
||
Sanchis-Gomar F,
|
||
Bassi A,
|
||
Lippi G</span><br />
|
||
<span class="medgenPMjournal">Clin Biochem</span>
|
||
2017 Aug;50(12):656-662.
|
||
Epub 2017 Feb 21
|
||
doi: 10.1016/j.clinbiochem.2017.02.016.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28235546" target="_blank">28235546</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24191431">Improving detection and treatment of liver cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Keane MG,
|
||
Pereira SP</span><br />
|
||
<span class="medgenPMjournal">Practitioner</span>
|
||
2013 Jul-Aug;257(1763):21-6, 2-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24191431" target="_blank">24191431</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23350673">Asia-Pacific consensus recommendations for endoscopic and interventional management of hilar cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rerknimitr R,
|
||
Angsuwatcharakon P,
|
||
Ratanachu-ek T,
|
||
Khor CJ,
|
||
Ponnudurai R,
|
||
Moon JH,
|
||
Seo DW,
|
||
Pantongrag-Brown L,
|
||
Sangchan A,
|
||
Pisespongsa P,
|
||
Akaraviputh T,
|
||
Reddy ND,
|
||
Maydeo A,
|
||
Itoi T,
|
||
Pausawasdi N,
|
||
Punamiya S,
|
||
Attasaranya S,
|
||
Devereaux B,
|
||
Ramchandani M,
|
||
Goh KL;
|
||
Asia-Pacific Working Group on Hepatobiliary Cancers</span><br />
|
||
<span class="medgenPMjournal">J Gastroenterol Hepatol</span>
|
||
2013 Apr;28(4):593-607.
|
||
doi: 10.1111/jgh.12128.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23350673" target="_blank">23350673</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22dark%20urine%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (14)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34889404">Management of hemolytic transfusion reactions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hendrickson JE,
|
||
Fasano RM</span><br />
|
||
<span class="medgenPMjournal">Hematology Am Soc Hematol Educ Program</span>
|
||
2021 Dec 10;2021(1):704-709.
|
||
doi: 10.1182/hematology.2021000308.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34889404" target="_blank">34889404</a><a href="/pmc/articles/PMC8791106" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34652109">Hepatitis A.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Langan RC,
|
||
Goodbred AJ</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2021 Oct 1;104(4):368-374.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34652109" target="_blank">34652109</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34276082">Rhabdomyolysis: Revisited.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta A,
|
||
Thorson P,
|
||
Penmatsa KR,
|
||
Gupta P</span><br />
|
||
<span class="medgenPMjournal">Ulster Med J</span>
|
||
2021 May;90(2):61-69.
|
||
Epub 2021 Jul 8
|
||
<span class="bold">PMID: </span><a href="/pubmed/34276082" target="_blank">34276082</a><a href="/pmc/articles/PMC8278949" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12467281">Methimazole-induced hepatotoxicity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Woeber KA</span><br />
|
||
<span class="medgenPMjournal">Endocr Pract</span>
|
||
2002 May-Jun;8(3):222-4.
|
||
doi: 10.4158/EP.8.3.222.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12467281" target="_blank">12467281</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1894526">Lovastatin-associated rhabdomyolysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sylvain-Moore H,
|
||
Worden JP Jr</span><br />
|
||
<span class="medgenPMjournal">Heart Lung</span>
|
||
1991 Sep;20(5 Pt 1):464-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1894526" target="_blank">1894526</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dark%20urine%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (119)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38453957">Alkaptonuria.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bernardini G,
|
||
Braconi D,
|
||
Zatkova A,
|
||
Sireau N,
|
||
Kujawa MJ,
|
||
Introne WJ,
|
||
Spiga O,
|
||
Geminiani M,
|
||
Gallagher JA,
|
||
Ranganath LR,
|
||
Santucci A</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Dis Primers</span>
|
||
2024 Mar 7;10(1):16.
|
||
doi: 10.1038/s41572-024-00498-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38453957" target="_blank">38453957</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35385123">Black fingers and dark urine: cold agglutinin disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Oda N,
|
||
Rokutanda R,
|
||
Terao T</span><br />
|
||
<span class="medgenPMjournal">QJM</span>
|
||
2022 Jun 7;115(6):393-394.
|
||
doi: 10.1093/qjmed/hcac095.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35385123" target="_blank">35385123</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34872769">Rhabdomyolysis: A syndrome to be considered.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baeza-Trinidad R</span><br />
|
||
<span class="medgenPMjournal">Med Clin (Barc)</span>
|
||
2022 Mar 25;158(6):277-283.
|
||
Epub 2021 Dec 3
|
||
doi: 10.1016/j.medcli.2021.09.025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34872769" target="_blank">34872769</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34652109">Hepatitis A.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Langan RC,
|
||
Goodbred AJ</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2021 Oct 1;104(4):368-374.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34652109" target="_blank">34652109</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34276082">Rhabdomyolysis: Revisited.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta A,
|
||
Thorson P,
|
||
Penmatsa KR,
|
||
Gupta P</span><br />
|
||
<span class="medgenPMjournal">Ulster Med J</span>
|
||
2021 May;90(2):61-69.
|
||
Epub 2021 Jul 8
|
||
<span class="bold">PMID: </span><a href="/pubmed/34276082" target="_blank">34276082</a><a href="/pmc/articles/PMC8278949" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dark%20urine%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (262)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36877581">Exertional Rhabdomyolysis in Athletes: Systematic Review and Current Perspectives.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bäcker HC,
|
||
Richards JT,
|
||
Kienzle A,
|
||
Cunningham J,
|
||
Braun KF</span><br />
|
||
<span class="medgenPMjournal">Clin J Sport Med</span>
|
||
2023 Mar 1;33(2):187-194.
|
||
Epub 2022 Oct 20
|
||
doi: 10.1097/JSM.0000000000001082.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36877581" target="_blank">36877581</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34872769">Rhabdomyolysis: A syndrome to be considered.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baeza-Trinidad R</span><br />
|
||
<span class="medgenPMjournal">Med Clin (Barc)</span>
|
||
2022 Mar 25;158(6):277-283.
|
||
Epub 2021 Dec 3
|
||
doi: 10.1016/j.medcli.2021.09.025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34872769" target="_blank">34872769</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34889404">Management of hemolytic transfusion reactions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hendrickson JE,
|
||
Fasano RM</span><br />
|
||
<span class="medgenPMjournal">Hematology Am Soc Hematol Educ Program</span>
|
||
2021 Dec 10;2021(1):704-709.
|
||
doi: 10.1182/hematology.2021000308.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34889404" target="_blank">34889404</a><a href="/pmc/articles/PMC8791106" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34652109">Hepatitis A.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Langan RC,
|
||
Goodbred AJ</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2021 Oct 1;104(4):368-374.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34652109" target="_blank">34652109</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27759359">Statin-Induced Rhabdomyolysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ambapkar SN,
|
||
Shetty N,
|
||
Dwivedy A</span><br />
|
||
<span class="medgenPMjournal">J Assoc Physicians India</span>
|
||
2016 Jul;64(7):93-94.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27759359" target="_blank">27759359</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dark%20urine%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (150)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34872769">Rhabdomyolysis: A syndrome to be considered.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baeza-Trinidad R</span><br />
|
||
<span class="medgenPMjournal">Med Clin (Barc)</span>
|
||
2022 Mar 25;158(6):277-283.
|
||
Epub 2021 Dec 3
|
||
doi: 10.1016/j.medcli.2021.09.025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34872769" target="_blank">34872769</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15686266">Neonatal cholestasis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Venigalla S,
|
||
Gourley GR</span><br />
|
||
<span class="medgenPMjournal">Semin Perinatol</span>
|
||
2004 Oct;28(5):348-55.
|
||
doi: 10.1053/j.semperi.2004.09.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15686266" target="_blank">15686266</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12208100">Neonatal cholestasis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McKiernan PJ</span><br />
|
||
<span class="medgenPMjournal">Semin Neonatol</span>
|
||
2002 Apr;7(2):153-65.
|
||
doi: 10.1053/siny.2002.0103.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12208100" target="_blank">12208100</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2655764">Drug-induced jaundice.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Neuberger J</span><br />
|
||
<span class="medgenPMjournal">Baillieres Clin Gastroenterol</span>
|
||
1989 Apr;3(2):447-66.
|
||
doi: 10.1016/0950-3528(89)90010-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2655764" target="_blank">2655764</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4684624">Halothane hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Qizilbash AH</span><br />
|
||
<span class="medgenPMjournal">Can Med Assoc J</span>
|
||
1973 Jan 20;108(2):171-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4684624" target="_blank">4684624</a><a href="/pmc/articles/PMC1941149" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dark%20urine%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (95)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37808625">Clinical and Epidemiological Characteristics of Rhabdomyolysis: A Retrospective Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sun K,
|
||
Shi Z,
|
||
Abudureheman Y,
|
||
Liu Q,
|
||
Zhao Y,
|
||
Zhang X,
|
||
Lv Q,
|
||
Zhang Y,
|
||
Shou S,
|
||
Jin H</span><br />
|
||
<span class="medgenPMjournal">Int J Clin Pract</span>
|
||
2023;2023:6396576.
|
||
Epub 2023 Sep 29
|
||
doi: 10.1155/2023/6396576.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37808625" target="_blank">37808625</a><a href="/pmc/articles/PMC10558265" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37730538">Clinical manifestation, staging and prognosis of hepatocellular carcinoma in Gambian patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bittaye SO,
|
||
Kambi A,
|
||
Tekanyi MAI,
|
||
Tamba S,
|
||
Sanneh L,
|
||
Sisawo MM,
|
||
Jatta A,
|
||
Fatty G,
|
||
Jeng A,
|
||
Jallow MS,
|
||
Leigh O,
|
||
Njie R</span><br />
|
||
<span class="medgenPMjournal">BMC Gastroenterol</span>
|
||
2023 Sep 20;23(1):321.
|
||
doi: 10.1186/s12876-023-02952-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37730538" target="_blank">37730538</a><a href="/pmc/articles/PMC10510158" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35254210">Clinical characteristics and outcomes of exertional rhabdomyolysis after indoor spinning: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Masuda Y,
|
||
Wam R,
|
||
Paik B,
|
||
Ngoh C,
|
||
Choong AM,
|
||
Ng JJ</span><br />
|
||
<span class="medgenPMjournal">Phys Sportsmed</span>
|
||
2023 Aug;51(4):294-305.
|
||
Epub 2022 Mar 10
|
||
doi: 10.1080/00913847.2022.2049645.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35254210" target="_blank">35254210</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23644623">Dysphagia in the setting of left ventricular assist device hemolysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mentz RJ,
|
||
Schlendorf K,
|
||
Hernandez AF,
|
||
Milano CA,
|
||
Felker GM,
|
||
Blue LJ,
|
||
Schroder JN,
|
||
Rogers JG,
|
||
Patel CB</span><br />
|
||
<span class="medgenPMjournal">ASAIO J</span>
|
||
2013 May-Jun;59(3):322-3.
|
||
doi: 10.1097/MAT.0b013e31828bbb00.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23644623" target="_blank">23644623</a><a href="/pmc/articles/PMC4158398" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22999899">Eosinophilic fasciitis with paroxysmal nocturnal hemoglobinuria.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Boysson H,
|
||
Chèze S,
|
||
Chapon F,
|
||
Le Mauff B,
|
||
Auzary C,
|
||
Geffray L</span><br />
|
||
<span class="medgenPMjournal">Joint Bone Spine</span>
|
||
2013 Mar;80(2):208-10.
|
||
Epub 2012 Sep 19
|
||
doi: 10.1016/j.jbspin.2012.07.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22999899" target="_blank">22999899</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dark%20urine%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (58)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/36877581">Exertional Rhabdomyolysis in Athletes: Systematic Review and Current Perspectives.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bäcker HC,
|
||
Richards JT,
|
||
Kienzle A,
|
||
Cunningham J,
|
||
Braun KF</span><br />
|
||
<span class="medgenPMjournal">Clin J Sport Med</span>
|
||
2023 Mar 1;33(2):187-194.
|
||
Epub 2022 Oct 20
|
||
doi: 10.1097/JSM.0000000000001082.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36877581" target="_blank">36877581</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35254210">Clinical characteristics and outcomes of exertional rhabdomyolysis after indoor spinning: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Masuda Y,
|
||
Wam R,
|
||
Paik B,
|
||
Ngoh C,
|
||
Choong AM,
|
||
Ng JJ</span><br />
|
||
<span class="medgenPMjournal">Phys Sportsmed</span>
|
||
2023 Aug;51(4):294-305.
|
||
Epub 2022 Mar 10
|
||
doi: 10.1080/00913847.2022.2049645.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35254210" target="_blank">35254210</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29189310">Muscle Damage Due to Fusidic Acid-Statin Interaction: Review of 75 Cases From the French Pharmacovigilance Database and Literature Reports.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bataillard M,
|
||
Beyens MN,
|
||
Mounier G,
|
||
Vergnon-Miszczycha D,
|
||
Bagheri H,
|
||
Cathebras P</span><br />
|
||
<span class="medgenPMjournal">Am J Ther</span>
|
||
2019 May/Jun;26(3):e375-e379.
|
||
doi: 10.1097/MJT.0000000000000679.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29189310" target="_blank">29189310</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dark%20urine%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
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|
||
|
||
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Dark%20urine" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
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</div>
|
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|
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<div class="portlet mgSection" id="ID_121">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22dark%20urine%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Dark%20urine%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Dark%20urine" target="_blank">MedlinePlus</a></li></ul></div>
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<li>
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<a href="/pubmed/clinical?term=Dark%20urine" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
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<a href="/pubmed?term=Dark%20urine%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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