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<meta name="keywords" content="C0152013, adenocarcinoma of lung, adenocarcinoma of lung, somatic, adenocarcinoma of the lung, adenocarcinoma, lung, adenocarcinomas, lung, bronchogenic lung adenocarcinoma, lung adenocarcinoma, lung adenocarcinomas, neoplastic process, non rare in europe: adenocarcinoma of the lung, non-small cell lung adenocarcinoma, nonsmall cell adenocarcinoma, pulmonary adenocarcinoma, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A carcinoma that arises from the lung and is characterized by the presence of malignant glandular epithelial cells. There is a male predilection with a male to female ratio of 2:1. Usually lung adenocarcinoma is asymptomatic and is identified through screening studies or as an incidental radiologic finding. If clinical symptoms are present they include shortness of breath, cough, hemoptysis, chest pain, and fever. Tobacco smoke is a known risk factor." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=57744
|
||
ConceptID=C0152013
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Lung adenocarcinoma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>57744</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0152013</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Adenocarcinoma of lung; Adenocarcinoma of lung, somatic</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Adenocarcinoma of lung (254626006)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0030078">HP:0030078</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0005061" target="_blank">MONDO:0005061</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/211980" target="_blank">211980</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=415268">ORPHA415268</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A carcinoma that arises from the lung and is characterized by the presence of malignant glandular epithelial cells. There is a male predilection with a male to female ratio of 2:1. Usually lung adenocarcinoma is asymptomatic and is identified through screening studies or as an incidental radiologic finding. If clinical symptoms are present they include shortness of breath, cough, hemoptysis, chest pain, and fever. Tobacco smoke is a known risk factor. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
|
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0024121[DISCUI]&test_type=Clinical" ref="ncbi_uid=7400">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/7400" ref="tree=GTR&ncbi_uid=7400&link_uid=7400" title="View MedGen record for 'Neoplasm of lung'">Neoplasm of lung</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0242379[DISCUI]&test_type=Clinical" ref="ncbi_uid=66885">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=66885" target="_blank" href="/omim/211980">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=66885" ref="ncbi_uid=66885">V</a></span></span><span class="TLline"><a href="/medgen/66885" ref="tree=GTR&ncbi_uid=66885&link_uid=66885" title="View MedGen record for 'Lung cancer'">Lung cancer</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0684249[DISCUI]&test_type=Clinical" ref="ncbi_uid=195765">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=195765" ref="ncbi_uid=195765">V</a></span></span><span class="TLline"><a href="/medgen/195765" ref="tree=GTR&ncbi_uid=195765&link_uid=195765" title="View MedGen record for 'Lung carcinoma'">Lung carcinoma</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=CN130014[DISCUI]&test_type=Clinical" ref="ncbi_uid=472093">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=472093" ref="ncbi_uid=472093">V</a></span></span><span class="TLline"><a href="/medgen/472093" ref="tree=GTR&ncbi_uid=472093&link_uid=472093" title="View MedGen record for 'EGFR-related lung cancer'">EGFR-related lung cancer</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=CN130015[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=472094">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/472094" ref="tree=GTR&ncbi_uid=472094&link_uid=472094" title="View MedGen record for 'GSTM1-related lung cancer'">GSTM1-related lung cancer</a></span></li><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0152013[DISCUI]&test_type=Clinical" ref="ncbi_uid=57744">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=57744" target="_blank" href="/omim/211980">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=57744" ref="ncbi_uid=57744">V</a></span></span><span class="TLline">Lung adenocarcinoma</span></li></ul></li></ul></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/277963" ref="tree=MeSH" title="MedGen record for Epithelial neoplasm">Epithelial neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/2867" ref="tree=MeSH" title="MedGen record for Carcinoma">Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/122" ref="tree=MeSH" title="MedGen record for Adenocarcinoma">Adenocarcinoma</a></span><ul><li><span class="matched_ds">Lung adenocarcinoma</span><ul><li><span class="TLline"><a href="/medgen/233130" ref="tree=MeSH" title="MedGen record for Acinar lung adenocarcinoma">Acinar lung adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1626367" ref="tree=MeSH" title="MedGen record for Invasive Lung Mucinous Adenocarcinoma">Invasive Lung Mucinous Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/883345" ref="tree=MeSH" title="MedGen record for Lepidic Adenocarcinoma">Lepidic Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1622442" ref="tree=MeSH" title="MedGen record for Lung Adenocarcinoma by AJCC v7 Stage">Lung Adenocarcinoma by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1618775" ref="tree=MeSH" title="MedGen record for Stage 0 Lung Adenocarcinoma AJCC v6 and v7">Stage 0 Lung Adenocarcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/163489" ref="tree=MeSH" title="MedGen record for Stage I Lung Adenocarcinoma AJCC v7">Stage I Lung Adenocarcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/234818" ref="tree=MeSH" title="MedGen record for Stage IA Lung Adenocarcinoma AJCC v7">Stage IA Lung Adenocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/236861" ref="tree=MeSH" title="MedGen record for Stage IB Lung Adenocarcinoma AJCC v7">Stage IB Lung Adenocarcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163490" ref="tree=MeSH" title="MedGen record for Stage II Lung Adenocarcinoma AJCC v7">Stage II Lung Adenocarcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/234826" ref="tree=MeSH" title="MedGen record for Stage IIA Lung Adenocarcinoma AJCC v7">Stage IIA Lung Adenocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/234831" ref="tree=MeSH" title="MedGen record for Stage IIB Lung Adenocarcinoma AJCC v7">Stage IIB Lung Adenocarcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/208936" ref="tree=MeSH" title="MedGen record for Stage III Lung Adenocarcinoma AJCC v7">Stage III Lung Adenocarcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/163582" ref="tree=MeSH" title="MedGen record for Stage IIIA Lung Adenocarcinoma AJCC v7">Stage IIIA Lung Adenocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/163583" ref="tree=MeSH" title="MedGen record for Stage IIIB Lung Adenocarcinoma AJCC v7">Stage IIIB Lung Adenocarcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163491" ref="tree=MeSH" title="MedGen record for Stage IV Lung Adenocarcinoma AJCC v7">Stage IV Lung Adenocarcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1620128" ref="tree=MeSH" title="MedGen record for Lung adenocarcinoma in situ">Lung adenocarcinoma in situ</a></span><ul><li><span class="TLline"><a href="/medgen/1618107" ref="tree=MeSH" title="MedGen record for Lung Mucinous Adenocarcinoma In Situ">Lung Mucinous Adenocarcinoma In Situ</a></span></li><li><span class="TLline"><a href="/medgen/1621951" ref="tree=MeSH" title="MedGen record for Lung Non-Mucinous Adenocarcinoma In Situ">Lung Non-Mucinous Adenocarcinoma In Situ</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/313370" ref="tree=MeSH" title="MedGen record for Lung colloid adenocarcinoma">Lung colloid adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1621526" ref="tree=MeSH" title="MedGen record for Lung Enteric Adenocarcinoma">Lung Enteric Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/353690" ref="tree=MeSH" title="MedGen record for Lung Fetal Adenocarcinoma">Lung Fetal Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/277443" ref="tree=MeSH" title="MedGen record for Lung occult adenocarcinoma">Lung occult adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1660921" ref="tree=MeSH" title="MedGen record for Metastatic Lung Adenocarcinoma">Metastatic Lung Adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1786216" ref="tree=MeSH" title="MedGen record for Advanced Lung Adenocarcinoma">Advanced Lung Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1763375" ref="tree=MeSH" title="MedGen record for Locally Advanced Lung Adenocarcinoma">Locally Advanced Lung Adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/2871" ref="tree=MeSH" title="MedGen record for Minimally invasive lung adenocarcinoma">Minimally invasive lung adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/266090" ref="tree=MeSH" title="MedGen record for Minimally Invasive Lung Mucinous Adenocarcinoma">Minimally Invasive Lung Mucinous Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/266089" ref="tree=MeSH" title="MedGen record for Nonmucinous bronchioloalveolar adenocarcinoma">Nonmucinous bronchioloalveolar adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/277495" ref="tree=MeSH" title="MedGen record for Papillary lung adenocarcinoma">Papillary lung adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/926281" ref="tree=MeSH" title="MedGen record for Lung Micropapillary Adenocarcinoma">Lung Micropapillary Adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/167748" ref="tree=MeSH" title="MedGen record for Recurrent Lung Adenocarcinoma">Recurrent Lung Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1791973" ref="tree=MeSH" title="MedGen record for Refractory Lung Adenocarcinoma">Refractory Lung Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234799" ref="tree=MeSH" title="MedGen record for Solid Lung Adenocarcinoma">Solid Lung Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1772480" ref="tree=MeSH" title="MedGen record for Unresectable Lung Adenocarcinoma">Unresectable Lung Adenocarcinoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
|
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|
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<div class="portlet mgSection" id="ID_112">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_66885"><div><strong>Lung cancer</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>66885</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0242379</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
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<div class="spaceAbove">A primary or metastatic malignant neoplasm involving the lung.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/66885">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_322656"><div><strong>Li-Fraumeni syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>322656</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1835398</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Li-Fraumeni syndrome (LFS) is a cancer predisposition syndrome associated with high risks for a broad spectrum of cancers including early-onset cancers. Five cancer types account for the majority of LFS tumors: adrenocortical carcinomas, breast cancer, central nervous system tumors, osteosarcomas, and soft-tissue sarcomas. Other cancers associated with LFS include leukemia, colorectal cancer, stomach cancer, lung cancer, melanoma, pediatric head and neck cancers, pancreatic cancer, and prostate cancer. Cancer survivors are at increased risk for developing additional primary cancers and treatment-related secondary cancers. The lifetime risks of cancer for women and men with classic LFS are 90% and 70%, respectively, and 50% of cancers occur prior to age 40 years.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/322656">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_482122"><div><strong>BAP1-related tumor predisposition syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>482122</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3280492</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">BAP1 tumor predisposition syndrome (BAP1-TPDS) is associated with an increased risk for a specific skin lesion, BAP1-inactivated melanocytic tumors (BIMT; formerly called atypical Spitz tumors), and the following cancers, in descending order of frequency: uveal (eye) melanoma (UM), malignant mesothelioma (MMe), cutaneous melanoma (CM), renal cell carcinoma (RCC), basal cell carcinoma (BCC), meningioma, and cholangiocarcinoma. Onychopapillomas, hepatocellular carcinoma, and ovarian sex cord-stromal tumors may also be associated with BAP1-TPDS. Affected individuals can have more than one type of primary cancer. In general, the median age of onset of these tumors is younger than in the general population. UM tends to be a more aggressive class 2 tumor with higher risk for metastasis and reduced survival compared to UM occurring in the general population. RCC is usually of clear cell morphology, but other pathologies have been reported. MMe, especially pleural, has better survival and responds better to platinum chemotherapy than MMe not associated with a germline BAP1 pathogenic variant. The penetrance, natural history, life-time cancer risk for carriers, and frequencies of BAP1-associated tumors are yet to be fully determined.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/482122">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1711127"><div><strong>Fanconi renotubular syndrome 5</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1711127</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5394473</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Fanconi renotubular syndrome-5 (FRTS5) is a mitochondrial disorder characterized by proximal renotubular dysfunction from birth, followed by progressive kidney disease and pulmonary fibrosis. It occurs only in individuals of Acadian descent (Crocker et al., 1997 and Hartmannova et al., 2016). For a discussion of genetic heterogeneity of Fanconi renotubular syndrome, see FRTS1 (134600).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1711127">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_482122" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">BAP1-related tumor predisposition syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1711127" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Fanconi renotubular syndrome 5</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_322656" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Li-Fraumeni syndrome 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_66885" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Lung cancer</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35276343">Small cell lung cancer transformation: From pathogenesis to treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yin X,
|
||
Li Y,
|
||
Wang H,
|
||
Jia T,
|
||
Wang E,
|
||
Luo Y,
|
||
Wei Y,
|
||
Qin Z,
|
||
Ma X</span><br />
|
||
<span class="medgenPMjournal">Semin Cancer Biol</span>
|
||
2022 Nov;86(Pt 2):595-606.
|
||
Epub 2022 Mar 8
|
||
doi: 10.1016/j.semcancer.2022.03.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35276343" target="_blank">35276343</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34246791">Liquid Biopsy for Advanced NSCLC: A Consensus Statement From the International Association for the Study of Lung Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rolfo C,
|
||
Mack P,
|
||
Scagliotti GV,
|
||
Aggarwal C,
|
||
Arcila ME,
|
||
Barlesi F,
|
||
Bivona T,
|
||
Diehn M,
|
||
Dive C,
|
||
Dziadziuszko R,
|
||
Leighl N,
|
||
Malapelle U,
|
||
Mok T,
|
||
Peled N,
|
||
Raez LE,
|
||
Sequist L,
|
||
Sholl L,
|
||
Swanton C,
|
||
Abbosh C,
|
||
Tan D,
|
||
Wakelee H,
|
||
Wistuba I,
|
||
Bunn R,
|
||
Freeman-Daily J,
|
||
Wynes M,
|
||
Belani C,
|
||
Mitsudomi T,
|
||
Gandara D</span><br />
|
||
<span class="medgenPMjournal">J Thorac Oncol</span>
|
||
2021 Oct;16(10):1647-1662.
|
||
Epub 2021 Jul 8
|
||
doi: 10.1016/j.jtho.2021.06.017.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34246791" target="_blank">34246791</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29371589">Cell death-based treatment of lung adenocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Denisenko TV,
|
||
Budkevich IN,
|
||
Zhivotovsky B</span><br />
|
||
<span class="medgenPMjournal">Cell Death Dis</span>
|
||
2018 Jan 25;9(2):117.
|
||
doi: 10.1038/s41419-017-0063-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29371589" target="_blank">29371589</a><a href="/pmc/articles/PMC5833343" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22lung%20adenocarcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (441)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37872108">Updates on lung adenocarcinoma: invasive size, grading and STAS.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Willner J,
|
||
Narula N,
|
||
Moreira AL</span><br />
|
||
<span class="medgenPMjournal">Histopathology</span>
|
||
2024 Jan;84(1):6-17.
|
||
Epub 2023 Oct 23
|
||
doi: 10.1111/his.15077.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37872108" target="_blank">37872108</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37657358">Identification of a disulfidptosis-related genes signature for prognostic implication in lung adenocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang J,
|
||
Zhang J,
|
||
Zhang F,
|
||
Lu S,
|
||
Guo S,
|
||
Shi R,
|
||
Zhai Y,
|
||
Gao Y,
|
||
Tao X,
|
||
Jin Z,
|
||
You L,
|
||
Wu J</span><br />
|
||
<span class="medgenPMjournal">Comput Biol Med</span>
|
||
2023 Oct;165:107402.
|
||
Epub 2023 Aug 28
|
||
doi: 10.1016/j.compbiomed.2023.107402.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37657358" target="_blank">37657358</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37552140">The expression and prognostic value of disulfidptosis progress in lung adenocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ni L,
|
||
Yang H,
|
||
Wu X,
|
||
Zhou K,
|
||
Wang S</span><br />
|
||
<span class="medgenPMjournal">Aging (Albany NY)</span>
|
||
2023 Aug 7;15(15):7741-7759.
|
||
doi: 10.18632/aging.204938.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37552140" target="_blank">37552140</a><a href="/pmc/articles/PMC10457049" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36032135">Prediction of prognosis, immunogenicity and efficacy of immunotherapy based on glutamine metabolism in lung adenocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu J,
|
||
Shen H,
|
||
Gu W,
|
||
Zheng H,
|
||
Wang Y,
|
||
Ma G,
|
||
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<div class="nl"><a target="_blank" href="/pubmed/30077210">Lung Adenocarcinoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Erickson LA</span><br />
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<div class="nl"><a target="_blank" href="/pubmed/37657358">Identification of a disulfidptosis-related genes signature for prognostic implication in lung adenocarcinoma.</a></div>
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Zhai Y,
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Epub 2023 Aug 28
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doi: 10.1016/j.compbiomed.2023.107402.
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2021 Apr;34(4):710-719.
|
||
Epub 2020 Oct 3
|
||
doi: 10.1038/s41379-020-00692-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33011748" target="_blank">33011748</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lung%20adenocarcinoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6992)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/39455981">Prognostic factors for resected invasive mucinous lung adenocarcinoma: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shen F,
|
||
Wu X,
|
||
Geng J,
|
||
Guo W,
|
||
Duan J</span><br />
|
||
<span class="medgenPMjournal">BMC Cancer</span>
|
||
2024 Oct 25;24(1):1317.
|
||
doi: 10.1186/s12885-024-13068-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39455981" target="_blank">39455981</a><a href="/pmc/articles/PMC11520044" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38303008">Prognostic factors for invasive mucinous adenocarcinoma of the lung: systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhao T,
|
||
Yi J,
|
||
Luo D,
|
||
Liu J,
|
||
Fan X,
|
||
Wu Q,
|
||
Wang W</span><br />
|
||
<span class="medgenPMjournal">World J Surg Oncol</span>
|
||
2024 Feb 2;22(1):41.
|
||
doi: 10.1186/s12957-024-03326-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38303008" target="_blank">38303008</a><a href="/pmc/articles/PMC10835932" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36583661">Computed Tomography Features and Tumor Spread Through Air Spaces in Lung Adenocarcinoma: A Meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gu Y,
|
||
Zheng B,
|
||
Zhao T,
|
||
Fan Y</span><br />
|
||
<span class="medgenPMjournal">J Thorac Imaging</span>
|
||
2023 Mar 1;38(2):W19-W29.
|
||
Epub 2022 Dec 28
|
||
doi: 10.1097/RTI.0000000000000693.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36583661" target="_blank">36583661</a><a href="/pmc/articles/PMC9936977" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31734255">Long non-coding RNA MALAT1 as a valuable biomarker for prognosis in osteosarcoma: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu M,
|
||
Yang P,
|
||
Mao G,
|
||
Deng J,
|
||
Peng G,
|
||
Ning X,
|
||
Yang H,
|
||
Sun H</span><br />
|
||
<span class="medgenPMjournal">Int J Surg</span>
|
||
2019 Dec;72:206-213.
|
||
Epub 2019 Nov 15
|
||
doi: 10.1016/j.ijsu.2019.11.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31734255" target="_blank">31734255</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21252716">International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Travis WD,
|
||
Brambilla E,
|
||
Noguchi M,
|
||
Nicholson AG,
|
||
Geisinger KR,
|
||
Yatabe Y,
|
||
Beer DG,
|
||
Powell CA,
|
||
Riely GJ,
|
||
Van Schil PE,
|
||
Garg K,
|
||
Austin JH,
|
||
Asamura H,
|
||
Rusch VW,
|
||
Hirsch FR,
|
||
Scagliotti G,
|
||
Mitsudomi T,
|
||
Huber RM,
|
||
Ishikawa Y,
|
||
Jett J,
|
||
Sanchez-Cespedes M,
|
||
Sculier JP,
|
||
Takahashi T,
|
||
Tsuboi M,
|
||
Vansteenkiste J,
|
||
Wistuba I,
|
||
Yang PC,
|
||
Aberle D,
|
||
Brambilla C,
|
||
Flieder D,
|
||
Franklin W,
|
||
Gazdar A,
|
||
Gould M,
|
||
Hasleton P,
|
||
Henderson D,
|
||
Johnson B,
|
||
Johnson D,
|
||
Kerr K,
|
||
Kuriyama K,
|
||
Lee JS,
|
||
Miller VA,
|
||
Petersen I,
|
||
Roggli V,
|
||
Rosell R,
|
||
Saijo N,
|
||
Thunnissen E,
|
||
Tsao M,
|
||
Yankelewitz D</span><br />
|
||
<span class="medgenPMjournal">J Thorac Oncol</span>
|
||
2011 Feb;6(2):244-85.
|
||
doi: 10.1097/JTO.0b013e318206a221.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21252716" target="_blank">21252716</a><a href="/pmc/articles/PMC4513953" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lung%20adenocarcinoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (58)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
||
<div class="portlet mgSection" id="ID_113">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul id="my-toc"></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_106">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0152013%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (18)</a></li>
|
||
<li><a href="/gtr/tests?term=C0152013%5bDISCUI%5d&filter=method%3A3%5F23" target="_blank">FISH-interphase (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C0152013%5bDISCUI%5d&filter=method%3A3%5F31" target="_blank">Fluorescence in situ hybridization (FISH) (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0152013%5bDISCUI%5d&filter=method%3A2%5F30" target="_blank">RNA analysis (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0152013%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (19)</a></li>
|
||
<li><a href="/gtr/tests?term=C0152013%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (1)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0152013%5bDISCUI%5d" target="_blank">See all (24)</a></total></li>
|
||
</ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_119">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=415268" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Lung%20adenocarcinoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_121">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22lung%20adenocarcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Lung%20adenocarcinoma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_116">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Consumer_resources">Consumer resources</h1><a sid="116" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.diseaseinfosearch.org/Adenocarcinoma+of+Lung/222" target="_blank">Genetic Alliance</a></li><li><a href="https://www.malacards.org/card/lung_cancer" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Lung%20adenocarcinoma" target="_blank">MedlinePlus</a></li><li><a href="https://rarediseases.info.nih.gov/diseases/5742/disease" target="_blank">NCATS Office of Rare Diseases Research (GARD)</a></li></ul></div>
|
||
</div>
|
||
</div>
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Reviews</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Reviews" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter"></a>
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||
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|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pubmed/clinical?term=Lung%20adenocarcinoma" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed?term=Lung%20adenocarcinoma%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<!-- MedGen supplemental column ends here -->
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&from_uid=57744" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0152013[DISCUI]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0152013[DISCUI]&test_type=Clinical" ref="log$=recordlinks">GTR(Clinical)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Clinical tests in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim&from_uid=57744" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related records in OMIM</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=medgen_pmc&from_uid=57744" ref="log$=recordlinks">PMC Articles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in PubMed Central Links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed&from_uid=57744" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed_omim&from_uid=57744" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="portlet">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Recent activity</h3>
|
||
</div>
|
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<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Shutter"></a>
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<div class="portlet_content">
|
||
<div id="HTDisplay" class="">
|
||
<input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Cmd" sid="1" type="hidden" />
|
||
<div class="action">
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory">
|
||
Clear
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn Off
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" sid="2" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOff" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn On
|
||
</a>
|
||
</div>
|
||
<ul id="activity">
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67d495b767c23b31e0b0adb6">Lung adenocarcinoma</a>
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