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<!--
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||
UID=57739
|
||
ConceptID=C0151900
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Increased circulating iron concentration</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>57739</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0151900</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Increased serum iron</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Serum iron raised (165624002); Serum iron above reference range (165624002)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0003452">HP:0003452</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">The concentration of iron in the blood circulation is above the upper limit of normal. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Increased circulating iron concentration</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/1701080" ref="tree=MeSH" title="MedGen record for Abnormal circulating metabolite concentration">Abnormal circulating metabolite concentration</a></span><ul><li><span class="TLline"><a href="/medgen/312393" ref="tree=MeSH" title="MedGen record for Abnormal blood ion concentration">Abnormal blood ion concentration</a></span><ul><li><span class="TLline"><a href="/medgen/869223" ref="tree=MeSH" title="MedGen record for Abnormal blood cation concentration">Abnormal blood cation concentration</a></span><ul><li><span class="TLline"><a href="/medgen/869164" ref="tree=MeSH" title="MedGen record for Abnormal blood transition element cation concentration">Abnormal blood transition element cation concentration</a></span><ul><li><span class="TLline"><a href="/medgen/869163" ref="tree=MeSH" title="MedGen record for Abnormality of iron homeostasis">Abnormality of iron homeostasis</a></span><ul><li><span class="TLline"><a href="/medgen/808235" ref="tree=MeSH" title="MedGen record for Abnormal circulating iron concentration">Abnormal circulating iron concentration</a></span><ul><li><span class="matched_ds">Increased circulating iron concentration</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_82768"><div><strong>Neonatal hemochromatosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>82768</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268059</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Neonatal hemochromatosis (NH) is characterized by hepatic failure in the newborn period and heavy iron staining in the liver. In addition, there is marked siderosis of extrahepatic tissues, including the heart and pancreas (Driscoll et al., 1988). Whitington (2007) postulated that some cases of neonatal hemochromatosis result from maternal alloimmunity directed at the fetal liver, and therefore do not represent an inherited mendelian disorder. Other causes may result from metabolic disease or perinatal infection. In particular, he commented that the disorder is not related to the family of inherited liver diseases that fall under the classification of hereditary hemochromatosis (see, e.g., 235200). Whitington (2007) proposed the term 'congenital alloimmune hepatitis.' In the past, the disorder has loosely been labeled 'neonatal hepatitis' and 'giant cell hepatitis,' which are pathologic findings in the liver representing a common response to a variety of insults, including cholestatic disorders and infection, among others (Fawaz et al., 1975; Knisely et al., 1987; Kelly et al., 2001).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/82768">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_341982"><div><strong>Hemochromatosis type 5</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>341982</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1851316</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare disorder of iron metabolism and transport characterised by elevated serum ferritin levels, increased serum iron, increased transferrin saturation and heavy iron deposition in hepatocytes. Iron deposition has also been indicated in heart and bone marrow, while haematological examination of peripheral blood shows no abnormalities.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/341982">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_388114"><div><strong>Hemochromatosis type 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>388114</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1858664</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">TFR2-related hemochromatosis (TFR2-HC) is characterized by increased intestinal iron absorption resulting in iron accumulation in the liver, heart, pancreas, and endocrine organs. Age of onset is earlier than in HFE-related hemochromatosis. The majority of individuals present with signs and symptoms of iron overload in the third decade (e.g., weakness, fatigue, abdominal pain, hepatomegaly, arthritis, arthralgia, and progressive increase in skin pigmentation). Others present as young adults with nonspecific symptoms and abnormal serum iron studies or as adults with abnormal serum iron studies and signs of organ involvement including cirrhosis, diabetes mellitus, arthropathy, hypogonadism, cardiomyopathy, and increase in skin pigmentation.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/388114">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_400428"><div><strong>GRACILE syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>400428</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1864002</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">GRACILE syndrome is an autosomal recessive lethal disorder characterized by fetal growth retardation, lactic acidosis, aminoaciduria, cholestasis, and abnormalities in iron metabolism. Patients develop fulminant lactic acidosis during the first day of life. Despite intensive care, about half of affected infants die during the first days of life, and the remainder within 4 months of life. Finnish and British patients have been reported, with slightly different phenotypes; the British patients have additional features of complex III deficiency and neurologic symptoms (Visapaa et al., 2002).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/400428">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_356321"><div><strong>Hemochromatosis type 2A</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>356321</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1865614</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Juvenile hemochromatosis is characterized by onset of severe iron overload occurring typically in the first to third decades of life. Males and females are equally affected. Prominent clinical features include hypogonadotropic hypogonadism, cardiomyopathy, glucose intolerance and diabetes, arthropathy, and liver fibrosis or cirrhosis. Hepatocellular cancer has been reported occasionally. The main cause of death is cardiac disease. If juvenile hemochromatosis is detected early enough and if blood is removed regularly through the process of phlebotomy to achieve iron depletion, morbidity and mortality are greatly reduced.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/356321">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_356040"><div><strong>Hemochromatosis type 2B</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>356040</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1865616</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Juvenile hemochromatosis is characterized by onset of severe iron overload occurring typically in the first to third decades of life. Males and females are equally affected. Prominent clinical features include hypogonadotropic hypogonadism, cardiomyopathy, glucose intolerance and diabetes, arthropathy, and liver fibrosis or cirrhosis. Hepatocellular cancer has been reported occasionally. The main cause of death is cardiac disease. If juvenile hemochromatosis is detected early enough and if blood is removed regularly through the process of phlebotomy to achieve iron depletion, morbidity and mortality are greatly reduced.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/356040">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_854011"><div><strong>Hemochromatosis type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>854011</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3469186</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">HFE-related hemochromatosis (HFE HC) is characterized by increased intestinal iron absorption and increased recycling of iron derived from senescent red blood cells. The phenotypic spectrum of HFE HC includes clinical HFE HC (increased serum ferritin and transferrin saturation and end-organ damage secondary to iron overload), biochemical HFE HC (increased serum ferritin and transferrin saturation without end-organ damage), and non-penetrant HFE HC (neither clinical manifestations of HFE HC nor iron overload are present, although elevated transferrin saturation may occur). Clinical HFE HC is characterized by excessive iron in the liver, pancreas, heart, skin, joints, and anterior pituitary gland. In untreated individuals, early manifestations include weakness, chronic fatigue, abdominal pain, weight loss, arthralgias, and diabetes mellitus. Individuals with HFE HC have an increased risk of cirrhosis when their serum ferritin is higher than 1,000 µg/L. Other findings of severe iron overload include hypogonadism, congestive heart failure, arrhythmias, and progressive increase in skin pigmentation. Clinical HFE HC is more common in males than females.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/854011">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_812483"><div><strong>Microcytic anemia with liver iron overload</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>812483</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3806153</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hypochromic microcytic anemia with iron overload is a condition that impairs the normal transport of iron in cells. Iron is an essential component of hemoglobin, which is the substance that red blood cells use to carry oxygen to cells and tissues throughout the body. In this condition, red blood cells cannot access iron in the blood, so there is a decrease of red blood cell production (anemia) that is apparent at birth. The red blood cells that are produced are abnormally small (microcytic) and pale (hypochromic). Hypochromic microcytic anemia with iron overload can lead to pale skin (pallor), tiredness (fatigue), and slow growth.\n\nIn hypochromic microcytic anemia with iron overload, the iron that is not used by red blood cells accumulates in the liver, which can impair its function over time. The liver problems typically become apparent in adolescence or early adulthood.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/812483">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1644087"><div><strong>Trichohepatoenteric syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1644087</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551982</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Trichohepatoenteric syndrome (THES), generally considered to be a neonatal enteropathy, is characterized by intractable diarrhea (seen in almost all affected children), woolly hair (seen in all), intrauterine growth restriction, facial dysmorphism, and short stature. Additional findings include poorly characterized immunodeficiency, recurrent infections, skin abnormalities, and liver disease. Mild intellectual disability (ID) is seen in about 50% of affected individuals. Less common findings include congenital heart defects and platelet anomalies. To date 52 affected individuals have been reported.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1644087">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1658844"><div><strong>Ferro-cerebro-cutaneous syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1658844</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4751570</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare genetic metabolic liver disease with characteristics of progressive neurodegeneration, cutaneous abnormalities including varying degrees of ichthyosis or seborrheic dermatitis, and systemic iron overload. Patients manifest with infantile-onset seizures, encephalopathy, abnormal eye movements, axial hypotonia with peripheral hypertonia, brisk reflexes, cortical blindness and deafness, myoclonus and hepato/splenomegaly, as well as oral manifestations including microdontia, widely spaced and pointed teeth with delayed eruption and gingival overgrowth.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1658844">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1658844" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ferro-cerebro-cutaneous syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_400428" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">GRACILE syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_854011" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hemochromatosis type 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_356321" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hemochromatosis type 2A</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_356040" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hemochromatosis type 2B</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (10)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_388114" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hemochromatosis type 3</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_341982" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hemochromatosis type 5</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_812483" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Microcytic anemia with liver iron overload</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_82768" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neonatal hemochromatosis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1644087" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Trichohepatoenteric syndrome 1</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39851221">Mechanisms Underlying Iron Deficiency-Induced Cardiac Disorders: Implications for Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cirovic A,
|
||
Starcevic A,
|
||
Ivanovski A,
|
||
Bogicevic D,
|
||
Orisakwe OE,
|
||
Cirovic A</span><br />
|
||
<span class="medgenPMjournal">Discov Med</span>
|
||
2025 Jan;37(192):31-41.
|
||
doi: 10.24976/Discov.Med.202537192.3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39851221" target="_blank">39851221</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37164495">Umbilical cord pH, blood gases, and lactate at birth: normal values, interpretation, and clinical utility.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Olofsson P</span><br />
|
||
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
|
||
2023 May;228(5S):S1222-S1240.
|
||
Epub 2023 Mar 19
|
||
doi: 10.1016/j.ajog.2022.07.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37164495" target="_blank">37164495</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27170390">Pathogenesis, Diagnosis and Treatment of Hemochromatosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zoller H,
|
||
Henninger B</span><br />
|
||
<span class="medgenPMjournal">Dig Dis</span>
|
||
2016;34(4):364-73.
|
||
Epub 2016 May 11
|
||
doi: 10.1159/000444549.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27170390" target="_blank">27170390</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(increased%20circulating%20iron%20concentration)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (8)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37164495">Umbilical cord pH, blood gases, and lactate at birth: normal values, interpretation, and clinical utility.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Olofsson P</span><br />
|
||
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
|
||
2023 May;228(5S):S1222-S1240.
|
||
Epub 2023 Mar 19
|
||
doi: 10.1016/j.ajog.2022.07.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37164495" target="_blank">37164495</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32044999">Dapagliflozin Suppresses Hepcidin And Increases Erythropoiesis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ghanim H,
|
||
Abuaysheh S,
|
||
Hejna J,
|
||
Green K,
|
||
Batra M,
|
||
Makdissi A,
|
||
Chaudhuri A,
|
||
Dandona P</span><br />
|
||
<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
|
||
2020 Apr 1;105(4)
|
||
doi: 10.1210/clinem/dgaa057.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32044999" target="_blank">32044999</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31668584">Modifiable pathways for colorectal cancer: a mendelian randomisation analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cornish AJ,
|
||
Law PJ,
|
||
Timofeeva M,
|
||
Palin K,
|
||
Farrington SM,
|
||
Palles C,
|
||
Jenkins MA,
|
||
Casey G,
|
||
Brenner H,
|
||
Chang-Claude J,
|
||
Hoffmeister M,
|
||
Kirac I,
|
||
Maughan T,
|
||
Brezina S,
|
||
Gsur A,
|
||
Cheadle JP,
|
||
Aaltonen LA,
|
||
Tomlinson I,
|
||
Dunlop MG,
|
||
Houlston RS</span><br />
|
||
<span class="medgenPMjournal">Lancet Gastroenterol Hepatol</span>
|
||
2020 Jan;5(1):55-62.
|
||
Epub 2019 Oct 24
|
||
doi: 10.1016/S2468-1253(19)30294-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31668584" target="_blank">31668584</a><a href="/pmc/articles/PMC7026696" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23843134">Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McDonald SJ,
|
||
Middleton P,
|
||
Dowswell T,
|
||
Morris PS</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2013 Jul 11;2013(7):CD004074.
|
||
doi: 10.1002/14651858.CD004074.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23843134" target="_blank">23843134</a><a href="/pmc/articles/PMC6544813" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19405553">Ferric carboxymaltose: a review of its use in iron-deficiency anaemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lyseng-Williamson KA,
|
||
Keating GM</span><br />
|
||
<span class="medgenPMjournal">Drugs</span>
|
||
2009;69(6):739-56.
|
||
doi: 10.2165/00003495-200969060-00007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19405553" target="_blank">19405553</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20iron%20concentration%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (152)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37632469">Relating Lipoprotein(a) Concentrations to Cardiovascular Event Risk After Acute Coronary Syndrome: A Comparison of 3 Tests.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Szarek M,
|
||
Reijnders E,
|
||
Jukema JW,
|
||
Bhatt DL,
|
||
Bittner VA,
|
||
Diaz R,
|
||
Fazio S,
|
||
Garon G,
|
||
Goodman SG,
|
||
Harrington RA,
|
||
Ruhaak LR,
|
||
Schwertfeger M,
|
||
Tsimikas S,
|
||
White HD,
|
||
Steg PG,
|
||
Cobbaert C,
|
||
Schwartz GG;
|
||
ODYSSEY OUTCOMES Investigators</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2024 Jan 16;149(3):192-203.
|
||
Epub 2023 Aug 26
|
||
doi: 10.1161/CIRCULATIONAHA.123.066398.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37632469" target="_blank">37632469</a><a href="/pmc/articles/PMC10782942" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38067440">New Perspectives on Circulating Ferritin: Its Role in Health and Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fonseca Ó,
|
||
Ramos AS,
|
||
Gomes LTS,
|
||
Gomes MS,
|
||
Moreira AC</span><br />
|
||
<span class="medgenPMjournal">Molecules</span>
|
||
2023 Nov 22;28(23)
|
||
doi: 10.3390/molecules28237707.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38067440" target="_blank">38067440</a><a href="/pmc/articles/PMC10708148" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37164495">Umbilical cord pH, blood gases, and lactate at birth: normal values, interpretation, and clinical utility.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Olofsson P</span><br />
|
||
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
|
||
2023 May;228(5S):S1222-S1240.
|
||
Epub 2023 Mar 19
|
||
doi: 10.1016/j.ajog.2022.07.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37164495" target="_blank">37164495</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36335431">Pitfalls in the interpretation of blood tests used to assess and monitor micronutrient nutrition status.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Berger MM,
|
||
Talwar D,
|
||
Shenkin A</span><br />
|
||
<span class="medgenPMjournal">Nutr Clin Pract</span>
|
||
2023 Feb;38(1):56-69.
|
||
Epub 2022 Nov 5
|
||
doi: 10.1002/ncp.10924.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36335431" target="_blank">36335431</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29762515">Iron Status and Gestational Diabetes-A Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kataria Y,
|
||
Wu Y,
|
||
Horskjær PH,
|
||
Mandrup-Poulsen T,
|
||
Ellervik C</span><br />
|
||
<span class="medgenPMjournal">Nutrients</span>
|
||
2018 May 15;10(5)
|
||
doi: 10.3390/nu10050621.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29762515" target="_blank">29762515</a><a href="/pmc/articles/PMC5986501" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20iron%20concentration%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (70)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36335431">Pitfalls in the interpretation of blood tests used to assess and monitor micronutrient nutrition status.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Berger MM,
|
||
Talwar D,
|
||
Shenkin A</span><br />
|
||
<span class="medgenPMjournal">Nutr Clin Pract</span>
|
||
2023 Feb;38(1):56-69.
|
||
Epub 2022 Nov 5
|
||
doi: 10.1002/ncp.10924.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36335431" target="_blank">36335431</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33918997">Iron Deficiency in Obesity and after Bariatric Surgery.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bjørklund G,
|
||
Peana M,
|
||
Pivina L,
|
||
Dosa A,
|
||
Aaseth J,
|
||
Semenova Y,
|
||
Chirumbolo S,
|
||
Medici S,
|
||
Dadar M,
|
||
Costea DO</span><br />
|
||
<span class="medgenPMjournal">Biomolecules</span>
|
||
2021 Apr 21;11(5)
|
||
doi: 10.3390/biom11050613.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33918997" target="_blank">33918997</a><a href="/pmc/articles/PMC8142987" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32044999">Dapagliflozin Suppresses Hepcidin And Increases Erythropoiesis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ghanim H,
|
||
Abuaysheh S,
|
||
Hejna J,
|
||
Green K,
|
||
Batra M,
|
||
Makdissi A,
|
||
Chaudhuri A,
|
||
Dandona P</span><br />
|
||
<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
|
||
2020 Apr 1;105(4)
|
||
doi: 10.1210/clinem/dgaa057.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32044999" target="_blank">32044999</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31668584">Modifiable pathways for colorectal cancer: a mendelian randomisation analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cornish AJ,
|
||
Law PJ,
|
||
Timofeeva M,
|
||
Palin K,
|
||
Farrington SM,
|
||
Palles C,
|
||
Jenkins MA,
|
||
Casey G,
|
||
Brenner H,
|
||
Chang-Claude J,
|
||
Hoffmeister M,
|
||
Kirac I,
|
||
Maughan T,
|
||
Brezina S,
|
||
Gsur A,
|
||
Cheadle JP,
|
||
Aaltonen LA,
|
||
Tomlinson I,
|
||
Dunlop MG,
|
||
Houlston RS</span><br />
|
||
<span class="medgenPMjournal">Lancet Gastroenterol Hepatol</span>
|
||
2020 Jan;5(1):55-62.
|
||
Epub 2019 Oct 24
|
||
doi: 10.1016/S2468-1253(19)30294-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31668584" target="_blank">31668584</a><a href="/pmc/articles/PMC7026696" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19405553">Ferric carboxymaltose: a review of its use in iron-deficiency anaemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lyseng-Williamson KA,
|
||
Keating GM</span><br />
|
||
<span class="medgenPMjournal">Drugs</span>
|
||
2009;69(6):739-56.
|
||
doi: 10.2165/00003495-200969060-00007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19405553" target="_blank">19405553</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20iron%20concentration%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (126)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37632469">Relating Lipoprotein(a) Concentrations to Cardiovascular Event Risk After Acute Coronary Syndrome: A Comparison of 3 Tests.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Szarek M,
|
||
Reijnders E,
|
||
Jukema JW,
|
||
Bhatt DL,
|
||
Bittner VA,
|
||
Diaz R,
|
||
Fazio S,
|
||
Garon G,
|
||
Goodman SG,
|
||
Harrington RA,
|
||
Ruhaak LR,
|
||
Schwertfeger M,
|
||
Tsimikas S,
|
||
White HD,
|
||
Steg PG,
|
||
Cobbaert C,
|
||
Schwartz GG;
|
||
ODYSSEY OUTCOMES Investigators</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2024 Jan 16;149(3):192-203.
|
||
Epub 2023 Aug 26
|
||
doi: 10.1161/CIRCULATIONAHA.123.066398.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37632469" target="_blank">37632469</a><a href="/pmc/articles/PMC10782942" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32044999">Dapagliflozin Suppresses Hepcidin And Increases Erythropoiesis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ghanim H,
|
||
Abuaysheh S,
|
||
Hejna J,
|
||
Green K,
|
||
Batra M,
|
||
Makdissi A,
|
||
Chaudhuri A,
|
||
Dandona P</span><br />
|
||
<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
|
||
2020 Apr 1;105(4)
|
||
doi: 10.1210/clinem/dgaa057.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32044999" target="_blank">32044999</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31668584">Modifiable pathways for colorectal cancer: a mendelian randomisation analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cornish AJ,
|
||
Law PJ,
|
||
Timofeeva M,
|
||
Palin K,
|
||
Farrington SM,
|
||
Palles C,
|
||
Jenkins MA,
|
||
Casey G,
|
||
Brenner H,
|
||
Chang-Claude J,
|
||
Hoffmeister M,
|
||
Kirac I,
|
||
Maughan T,
|
||
Brezina S,
|
||
Gsur A,
|
||
Cheadle JP,
|
||
Aaltonen LA,
|
||
Tomlinson I,
|
||
Dunlop MG,
|
||
Houlston RS</span><br />
|
||
<span class="medgenPMjournal">Lancet Gastroenterol Hepatol</span>
|
||
2020 Jan;5(1):55-62.
|
||
Epub 2019 Oct 24
|
||
doi: 10.1016/S2468-1253(19)30294-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31668584" target="_blank">31668584</a><a href="/pmc/articles/PMC7026696" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30586731">Myocardial and Systemic Inflammation in Acute Stress-Induced (Takotsubo) Cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Scally C,
|
||
Abbas H,
|
||
Ahearn T,
|
||
Srinivasan J,
|
||
Mezincescu A,
|
||
Rudd A,
|
||
Spath N,
|
||
Yucel-Finn A,
|
||
Yuecel R,
|
||
Oldroyd K,
|
||
Dospinescu C,
|
||
Horgan G,
|
||
Broadhurst P,
|
||
Henning A,
|
||
Newby DE,
|
||
Semple S,
|
||
Wilson HM,
|
||
Dawson DK</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2019 Mar 26;139(13):1581-1592.
|
||
doi: 10.1161/CIRCULATIONAHA.118.037975.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30586731" target="_blank">30586731</a><a href="/pmc/articles/PMC6438459" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27941640">Fibroblast Growth Factor-23-A Potential Uremic Toxin.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kuczera P,
|
||
Adamczak M,
|
||
Wiecek A</span><br />
|
||
<span class="medgenPMjournal">Toxins (Basel)</span>
|
||
2016 Dec 8;8(12)
|
||
doi: 10.3390/toxins8120369.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27941640" target="_blank">27941640</a><a href="/pmc/articles/PMC5198563" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20iron%20concentration%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (68)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37632469">Relating Lipoprotein(a) Concentrations to Cardiovascular Event Risk After Acute Coronary Syndrome: A Comparison of 3 Tests.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Szarek M,
|
||
Reijnders E,
|
||
Jukema JW,
|
||
Bhatt DL,
|
||
Bittner VA,
|
||
Diaz R,
|
||
Fazio S,
|
||
Garon G,
|
||
Goodman SG,
|
||
Harrington RA,
|
||
Ruhaak LR,
|
||
Schwertfeger M,
|
||
Tsimikas S,
|
||
White HD,
|
||
Steg PG,
|
||
Cobbaert C,
|
||
Schwartz GG;
|
||
ODYSSEY OUTCOMES Investigators</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2024 Jan 16;149(3):192-203.
|
||
Epub 2023 Aug 26
|
||
doi: 10.1161/CIRCULATIONAHA.123.066398.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37632469" target="_blank">37632469</a><a href="/pmc/articles/PMC10782942" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37164495">Umbilical cord pH, blood gases, and lactate at birth: normal values, interpretation, and clinical utility.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Olofsson P</span><br />
|
||
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
|
||
2023 May;228(5S):S1222-S1240.
|
||
Epub 2023 Mar 19
|
||
doi: 10.1016/j.ajog.2022.07.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37164495" target="_blank">37164495</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31668584">Modifiable pathways for colorectal cancer: a mendelian randomisation analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cornish AJ,
|
||
Law PJ,
|
||
Timofeeva M,
|
||
Palin K,
|
||
Farrington SM,
|
||
Palles C,
|
||
Jenkins MA,
|
||
Casey G,
|
||
Brenner H,
|
||
Chang-Claude J,
|
||
Hoffmeister M,
|
||
Kirac I,
|
||
Maughan T,
|
||
Brezina S,
|
||
Gsur A,
|
||
Cheadle JP,
|
||
Aaltonen LA,
|
||
Tomlinson I,
|
||
Dunlop MG,
|
||
Houlston RS</span><br />
|
||
<span class="medgenPMjournal">Lancet Gastroenterol Hepatol</span>
|
||
2020 Jan;5(1):55-62.
|
||
Epub 2019 Oct 24
|
||
doi: 10.1016/S2468-1253(19)30294-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31668584" target="_blank">31668584</a><a href="/pmc/articles/PMC7026696" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23843134">Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McDonald SJ,
|
||
Middleton P,
|
||
Dowswell T,
|
||
Morris PS</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2013 Jul 11;2013(7):CD004074.
|
||
doi: 10.1002/14651858.CD004074.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23843134" target="_blank">23843134</a><a href="/pmc/articles/PMC6544813" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19405553">Ferric carboxymaltose: a review of its use in iron-deficiency anaemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lyseng-Williamson KA,
|
||
Keating GM</span><br />
|
||
<span class="medgenPMjournal">Drugs</span>
|
||
2009;69(6):739-56.
|
||
doi: 10.2165/00003495-200969060-00007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19405553" target="_blank">19405553</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20iron%20concentration%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (116)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/32716555">Blood transfusion for preventing primary and secondary stroke in people with sickle cell disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Estcourt LJ,
|
||
Kohli R,
|
||
Hopewell S,
|
||
Trivella M,
|
||
Wang WC</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2020 Jul 27;7(7):CD003146.
|
||
doi: 10.1002/14651858.CD003146.pub4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32716555" target="_blank">32716555</a><a href="/pmc/articles/PMC7388696" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32443563">Effects of Dietary or Supplementary Micronutrients on Sex Hormones and IGF-1 in Middle and Older Age: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Janjuha R,
|
||
Bunn D,
|
||
Hayhoe R,
|
||
Hooper L,
|
||
Abdelhamid A,
|
||
Mahmood S,
|
||
Hayden-Case J,
|
||
Appleyard W,
|
||
Morris S,
|
||
Welch A</span><br />
|
||
<span class="medgenPMjournal">Nutrients</span>
|
||
2020 May 18;12(5)
|
||
doi: 10.3390/nu12051457.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32443563" target="_blank">32443563</a><a href="/pmc/articles/PMC7284480" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/31454800">Selenium and Other Trace Elements in the Etiology of Parkinson's Disease: A Systematic Review and Meta-Analysis of Case-Control Studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Adani G,
|
||
Filippini T,
|
||
Michalke B,
|
||
Vinceti M</span><br />
|
||
<span class="medgenPMjournal">Neuroepidemiology</span>
|
||
2020;54(1):1-23.
|
||
Epub 2019 Aug 27
|
||
doi: 10.1159/000502357.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31454800" target="_blank">31454800</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28094851">Blood transfusion for preventing primary and secondary stroke in people with sickle cell disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Estcourt LJ,
|
||
Fortin PM,
|
||
Hopewell S,
|
||
Trivella M,
|
||
Wang WC</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2017 Jan 17;1(1):CD003146.
|
||
doi: 10.1002/14651858.CD003146.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28094851" target="_blank">28094851</a><a href="/pmc/articles/PMC6464911" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23843134">Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McDonald SJ,
|
||
Middleton P,
|
||
Dowswell T,
|
||
Morris PS</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2013 Jul 11;2013(7):CD004074.
|
||
doi: 10.1002/14651858.CD004074.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23843134" target="_blank">23843134</a><a href="/pmc/articles/PMC6544813" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20iron%20concentration%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div></div>
|
||
</div>
|
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