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<meta name="keywords" content="C0021122, disinhibition, disorders, impulse control, disruptive, impulse control, and conduct disorders, icd, impulse control disorder, impulse control disorders, impulse-control disorder, impulse-control disorders, mental or behavioral dysfunction, self-control, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Reduced ability to control, or a failure to resist a temptation, urge, or impulse. Examples include disregard for social conventions, general impulsivity, and poor risk assessment." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=5769
|
||
ConceptID=C0021122
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-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Impulse control disorder</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5769</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0021122</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Mental or Behavioral Dysfunction</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Disinhibition</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Impulse control disorder (66347000)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000734">HP:0000734</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0001162" target="_blank">MONDO:0001162</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Reduced ability to control, or a failure to resist a temptation, urge, or impulse. Examples include disregard for social conventions, general impulsivity, and poor risk assessment. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Impulse control disorder</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/105425" ref="tree=MeSH" title="MedGen record for Abnormality of the nervous system">Abnormality of the nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/868417" ref="tree=MeSH" title="MedGen record for Abnormal nervous system physiology">Abnormal nervous system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/868938" ref="tree=MeSH" title="MedGen record for Abnormality of mental function">Abnormality of mental function</a></span><ul><li><span class="TLline"><a href="/medgen/1056192" ref="tree=MeSH" title="MedGen record for Abnormal affect">Abnormal affect</a></span><ul><li><span class="TLline"><a href="/medgen/1053648" ref="tree=MeSH" title="MedGen record for Abnormal volitional state">Abnormal volitional state</a></span><ul><li><span class="TLline"><a href="/medgen/1853215" ref="tree=MeSH" title="MedGen record for Abnormally increased volition">Abnormally increased volition</a></span><ul><li><span class="matched_ds">Impulse control disorder</span><ul><li><span class="TLline"><a href="/medgen/1375" ref="tree=MeSH" title="MedGen record for Aggressive behavior">Aggressive behavior</a></span><ul><li><span class="TLline"><a href="/medgen/1853121" ref="tree=MeSH" title="MedGen record for Aggression towards others">Aggression towards others</a></span><ul><li><span class="TLline"><a href="/medgen/1841702" ref="tree=MeSH" title="MedGen record for Aggression toward non-caregivers">Aggression toward non-caregivers</a></span></li><li><span class="TLline"><a href="/medgen/1853116" ref="tree=MeSH" title="MedGen record for Aggression towards caregivers">Aggression towards caregivers</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/98076" ref="tree=MeSH" title="MedGen record for Bullying">Bullying</a></span></li><li><span class="TLline"><a href="/medgen/18178" ref="tree=MeSH" title="MedGen record for Oppositional defiant disorder">Oppositional defiant disorder</a></span></li><li><span class="TLline"><a href="/medgen/98408" ref="tree=MeSH" title="MedGen record for Violent behavior">Violent behavior</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/98406" ref="tree=MeSH" title="MedGen record for Hyperactivity">Hyperactivity</a></span><ul><li><span class="TLline"><a href="/medgen/220387" ref="tree=MeSH" title="MedGen record for Attention deficit hyperactivity disorder">Attention deficit hyperactivity disorder</a></span><ul><li><span class="TLline"><a href="/medgen/473060" ref="tree=MeSH" title="MedGen record for Attention deficit hyperactivity disorder, inattentive type">Attention deficit hyperactivity disorder, inattentive type</a></span></li><li><span class="TLline"><a href="/medgen/1004009" ref="tree=MeSH" title="MedGen record for Hereditary attention deficit-hyperactivity disorder">Hereditary attention deficit-hyperactivity disorder</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/43850" ref="tree=MeSH" title="MedGen record for Impulsivity">Impulsivity</a></span><ul><li><span class="TLline"><a href="/medgen/109373" ref="tree=MeSH" title="MedGen record for Compulsive behaviors">Compulsive behaviors</a></span><ul><li><span class="TLline"><a href="/medgen/88373" ref="tree=MeSH" title="MedGen record for Addictive behavior">Addictive behavior</a></span></li><li><span class="TLline"><a href="/medgen/1841736" ref="tree=MeSH" title="MedGen record for Atypical sorting">Atypical sorting</a></span></li><li><span class="TLline"><a href="/medgen/603043" ref="tree=MeSH" title="MedGen record for Collectionism">Collectionism</a></span></li><li><span class="TLline"><a href="/medgen/1841724" ref="tree=MeSH" title="MedGen record for Excessive checking">Excessive checking</a></span></li><li><span class="TLline"><a href="/medgen/1841977" ref="tree=MeSH" title="MedGen record for Excessive cleaning">Excessive cleaning</a></span></li><li><span class="TLline"><a href="/medgen/1841840" ref="tree=MeSH" title="MedGen record for Excessive hand washing">Excessive hand washing</a></span></li><li><span class="TLline"><a href="/medgen/5974" ref="tree=MeSH" title="MedGen record for Kleptomania">Kleptomania</a></span></li><li><span class="TLline"><a href="/medgen/322417" ref="tree=MeSH" title="MedGen record for Obsessive-compulsive trait">Obsessive-compulsive trait</a></span></li><li><span class="TLline"><a href="/medgen/42028" ref="tree=MeSH" title="MedGen record for Pyromania">Pyromania</a></span></li><li><span class="TLline"><a href="/medgen/853666" ref="tree=MeSH" title="MedGen record for Tics">Tics</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1841637" ref="tree=MeSH" title="MedGen record for Insistence on sameness">Insistence on sameness</a></span><ul><li><span class="TLline"><a href="/medgen/1842039" ref="tree=MeSH" title="MedGen record for Abnormal rituals">Abnormal rituals</a></span></li><li><span class="TLline"><a href="/medgen/1853268" ref="tree=MeSH" title="MedGen record for Inflexible adherence to routines">Inflexible adherence to routines</a></span></li><li><span class="TLline"><a href="/medgen/1841659" ref="tree=MeSH" title="MedGen record for Resistance to trivial environmental changes">Resistance to trivial environmental changes</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/7116" ref="tree=MeSH" title="MedGen record for intermittent explosive disorder">intermittent explosive disorder</a></span></li><li><span class="TLline"><a href="/medgen/14632" ref="tree=MeSH" title="MedGen record for Pathological gambling">Pathological gambling</a></span></li><li><span class="TLline"><a href="/medgen/1853270" ref="tree=MeSH" title="MedGen record for Risky behavior">Risky behavior</a></span></li><li><span class="TLline"><a href="/medgen/21654" ref="tree=MeSH" title="MedGen record for Trichotillomania">Trichotillomania</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_116020"><div><strong>Pick disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>116020</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0236642</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pick disease refers to the neuropathologic finding of 'Pick bodies,' which are argyrophilic, intraneuronal inclusions, and 'Pick cells,' which are enlarged neurons. The clinical correlates of Pick disease of brain include those of frontotemporal dementia, which encompass the behavioral variant of FTD, semantic dementia, and progressive nonfluent aphasia (summary by Piguet et al., 2011). Kertesz (2003) suggested the term 'Pick complex' to represent the overlapping syndromes of FTD, primary progressive aphasia (PPA), corticobasal degeneration (CBD), progressive supranuclear palsy (601104), and FTD with motor neuron disease. He noted that frontotemporal dementia may also be referred to as 'clinical Pick disease,' and that the term 'Pick disease' should be restricted to the pathologic finding of Pick bodies.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/116020">Condition Record</a></div></div>
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||
<div class="divPopper rprt" id="rdis_83266"><div><strong>Frontotemporal dementia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>83266</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0338451</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">In general, frontotemporal dementia (FTD) refers to a clinical manifestation of the pathologic finding of frontotemporal lobar degeneration (FTLD). FTD, the most common subtype of FTLD, is a behavioral variant characterized by changes in social and personal conduct with loss of volition, executive dysfunction, loss of abstract thought, and decreased speech output. A second clinical subtype of FTLD is 'semantic dementia,' characterized by specific loss of comprehension of language and impaired facial and object recognition. A third clinical subtype of FTLD is 'primary progressive aphasia' (PPA), characterized by a reduction in speech production, speech errors, and word retrieval difficulties resulting in mutism and an inability to communicate. All subtypes have relative preservation of memory, at least in the early stages. FTLD is often associated with parkinsonism or motor neuron disease (MND) resembling amyotrophic lateral sclerosis (ALS; 105400) (reviews by Tolnay and Probst, 2002 and Mackenzie and Rademakers, 2007). Mackenzie et al. (2009, 2010) provided a classification of FTLD subtypes according to the neuropathologic findings (see PATHOGENESIS below). Clinical Variability of Tauopathies Tauopathies comprise a clinically variable group of neurodegenerative diseases characterized neuropathologically by accumulation of abnormal MAPT-positive inclusions in nerve and/or glial cells. In addition to frontotemporal dementia, semantic dementia, and PPA, different clinical syndromes with overlapping features have been described, leading to confusion in the terminology (Tolnay and Probst, 2002). Other terms used historically include parkinsonism and dementia with pallidopontonigral degeneration (PPND) (Wszolek et al., 1992); disinhibition-dementia-parkinsonism-amyotrophy complex (DDPAC) (Lynch et al., 1994); frontotemporal dementia with parkinsonism (FLDEM) (Yamaoka et al., 1996); and multiple system tauopathy with presenile dementia (MSTD) (Spillantini et al., 1997). These disorders are characterized by variable degrees of frontal lobe dementia, parkinsonism, motor neuron disease, and amyotrophy. Other neurodegenerative disorders associated with mutations in the MAPT gene include Pick disease (172700) and progressive supranuclear palsy (PSP; 601104). Inherited neurodegenerative tauopathies linked to chromosome 17 and caused by mutation in the MAPT gene have also collectively been termed 'FTDP17' (Lee et al., 2001). Kertesz (2003) suggested the term 'Pick complex' to represent the overlapping syndromes of FTD, primary progressive aphasia (PPA), corticobasal degeneration (CBD), PSP, and FTD with motor neuron disease. He noted that frontotemporal dementia may also be referred to as 'clinical Pick disease' and that the term 'Pick disease' should be restricted to the pathologic finding of Pick bodies. Genetic Heterogeneity of Frontotemporal Lobar Degeneration Mutations in several different genes can cause frontotemporal dementia and frontotemporal lobar degeneration, with or without motor neuron disease. See FTD2 (607485), caused by mutation in the GRN gene (138945) on chromosome 17q21; FTDALS7 (600795), caused by mutation in the CHMP2B gene (609512) on chromosome 3p11; inclusion body myopathy with Paget disease and FTD (IBMPFD; 167320), caused by mutation in the VCP gene (601023) on chromosome 9p13; ALS6 (608030), caused by mutation in the FUS gene (137070) on 16p11; ALS10 (612069), caused by mutation in the TARDBP gene (605078) on 1p36; and FTDALS1 (105550), caused by mutation in the C9ORF72 gene (614260) on 9p21. In 1 family with FTD, a mutation was identified in the presenilin-1 gene (PSEN1; 104311) on chromosome 14, which is usually associated with a familial form of early-onset Alzheimer disease (AD3; 607822).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/83266">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_98277"><div><strong>Chorea-acanthocytosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98277</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0393576</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">VPS13A disease, caused by VPS13A loss-of-function pathogenic variants, is characterized by a spectrum of movement disorders (chorea, dystonia, tics, sometimes parkinsonism); predominant orofacial choreic and dystonic movements and tics (with involuntary tongue protrusion on attempted swallowing, habitual tongue and lip biting resulting in self-mutilation, involuntary vocalizations); dysarthria and dysphagia; psychiatric, cognitive, and behavioral changes ("frontal lobe type"); seizures; and progressive neuromuscular involvement. Huntingtonism (triad of progressive movement disorder and cognitive and behavioral alterations) is a typical presentation. Phenotypic variability is considerable even within the same family, including for monozygotic twins. Mean age of onset is about 30 years. VPS13A disease runs a chronic progressive course and may lead to major disability within a few years. Some affected individuals are bedridden or wheelchair dependent by the third decade. Age at death ranges from 28 to 61 years; several instances of sudden unexplained death or death during epileptic seizures have been reported.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/98277">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_318833"><div><strong>Frontotemporal dementia and/or amyotrophic lateral sclerosis 7</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>318833</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1833296</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">CHMP2B frontotemporal dementia (CHMP2B-FTD) has been described in a single family from Denmark, in one individual with familial FTD from Belgium, and in one individual with FTD and no family history. It typically starts between ages 46 and 65 years with subtle personality changes and slowly progressive behavioral changes, dysexecutive syndrome, dyscalculia, and language disturbances. Disinhibition or loss of initiative is the most common presenting symptom. The disease progresses over a few years into profound dementia with extrapyramidal symptoms and mutism. Several individuals have developed an asymmetric akinetic rigid syndrome with arm and gait dystonia and pyramidal signs that may be related to treatment with neuroleptic drugs. Symptoms and disease course are highly variable. Disease duration may be as short as three years or longer than 20 years.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/318833">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_333403"><div><strong>Fragile X-associated tremor/ataxia syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>333403</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1839780</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">FMR1 disorders include fragile X syndrome (FXS), fragile X-associated tremor/ataxia syndrome (FXTAS), and fragile X-associated primary ovarian insufficiency (FXPOI). Fragile X syndrome occurs in individuals with an FMR1 full mutation or other loss-of-function variant and is nearly always characterized in affected males by developmental delay and intellectual disability along with a variety of behavioral issues. Autism spectrum disorder is present in 50%-70% of individuals with FXS. Affected males may have characteristic craniofacial features (which become more obvious with age) and medical problems including hypotonia, gastroesophageal reflux, strabismus, seizures, sleep disorders, joint laxity, pes planus, scoliosis, and recurrent otitis media. Adults may have mitral valve prolapse or aortic root dilatation. The physical and behavioral features seen in males with FXS have been reported in females heterozygous for the FMR1 full mutation, but with lower frequency and milder involvement. FXTAS occurs in individuals who have an FMR1 premutation and is characterized by late-onset, progressive cerebellar ataxia and intention tremor followed by cognitive impairment. Psychiatric disorders are common. Age of onset is typically between 60 and 65 years and is more common among males who are hemizygous for the premutation (40%) than among females who are heterozygous for the premutation (16%-20%). FXPOI, defined as hypergonadotropic hypogonadism before age 40 years, has been observed in 20% of women who carry a premutation allele compared to 1% in the general population.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/333403">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_375285"><div><strong>GRN-related frontotemporal lobar degeneration with Tdp43 inclusions</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>375285</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1843792</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">The spectrum of GRN frontotemporal dementia (GRN-FTD) includes the behavioral variant (bvFTD), primary progressive aphasia (PPA; further subcategorized as progressive nonfluent aphasia [PNFA] and semantic dementia [SD]), and movement disorders with extrapyramidal features such as parkinsonism and corticobasal syndrome (CBS). A broad range of clinical features both within and between families is observed. The age of onset ranges from 35 to 87 years. Behavioral disturbances are the most common early feature, followed by progressive aphasia. Impairment in executive function manifests as loss of judgment and insight. In early stages, PPA often manifests as deficits in naming, word finding, or word comprehension. In late stages, affected individuals often become mute and lose their ability to communicate. Early findings of parkinsonism include rigidity, bradykinesia or akinesia (slowing or absence of movements), limb dystonia, apraxia (loss of ability to carry out learned purposeful movements), and disequilibrium. Late motor findings may include myoclonus, dysarthria, and dysphagia. Most affected individuals eventually lose the ability to walk. Disease duration is three to 12 years.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/375285">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_381211"><div><strong>Neuroferritinopathy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>381211</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1853578</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Neuroferritinopathy is an adult-onset progressive movement disorder characterized by chorea or dystonia and speech and swallowing deficits. The movement disorder typically affects one or two limbs and progresses to become more generalized within 20 years of disease onset. When present, asymmetry in the movement abnormalities remains throughout the course of the disorder. Most individuals develop a characteristic orofacial action-specific dystonia related to speech that leads to dysarthrophonia. Frontalis overactivity and orolingual dyskinesia are common. Cognitive deficits and behavioral issues become major problems with time.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/381211">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_401097"><div><strong>Hereditary spastic paraplegia 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>401097</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1866855</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Spastic paraplegia 4 (SPG4; also known as SPAST-HSP) is characterized by insidiously progressive bilateral lower-limb gait spasticity. More than 50% of affected individuals have some weakness in the legs and impaired vibration sense at the ankles. Sphincter disturbances are very common. Onset is insidious, mostly in young adulthood, although symptoms may start as early as age one year and as late as age 76 years. Intrafamilial variation is considerable.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/401097">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_357007"><div><strong>Perry syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>357007</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1868594</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">The spectrum of DCTN1-related neurodegeneration includes Perry syndrome, distal hereditary motor neuronopathy type 7B (dHMN7B), frontotemporal dementia (FTD), motor neuron disease / amyotrophic lateral sclerosis (ALS), and progressive supranuclear palsy. Some individuals present with overlapping phenotypes (e.g., FTD-ALS, Perry syndrome-dHMN7B). Perry syndrome (the most common of the phenotypes associated with DCTN1) is characterized by parkinsonism, neuropsychiatric symptoms, hypoventilation, and weight loss. The mean age of onset in those with Perry syndrome is 49 years (range: 35-70 years), and the mean disease duration is five years (range: 2-14 years). In most affected persons, the reported cause/circumstance of death relates to sudden death/hypoventilation or suicide.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/357007">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_383137"><div><strong>Amyotrophic lateral sclerosis type 10</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>383137</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2677565</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">In this GeneReview, TARDBP amyotrophic lateral sclerosis-frontotemporal dementia (TARDBP-ALS-FTD) refers to the spectrum of phenotypes caused by pathogenic variants in TARDBP, the gene encoding TDP-43. The phenotypic spectrum encompasses pure (i.e., without other neurologic findings) amyotrophic lateral sclerosis (ALS; most common), pure (i.e., without other neurologic findings) frontotemporal dementia (FTD; rare), a combination of ALS and FTD, and atypical neurologic phenotypes (very rare). Individuals with the same TARDBP pathogenic variant (even within the same family) may have clinical features that vary in both type and severity. Common manifestations are dysarthria and dysphagia; less common manifestations can include parkinsonism, cognitive deterioration, and behavioral and psychological manifestations of dementia. Life expectancy for TARDBP-ALS is highly variable and mainly associated with an individual's clinical features; overall disease duration averages three to five years. For TARDBP-FTD, disease duration averages one to 16 years.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/383137">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_902979"><div><strong>Frontotemporal dementia and/or amyotrophic lateral sclerosis 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>902979</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4225325</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Frontotemporal dementia and/or amyotrophic lateral sclerosis-4 is an autosomal dominant neurodegenerative disorder characterized by adult or late adult onset of cognitive impairment, behavioral abnormalities, and speech apraxia and/or upper and lower motor neuron signs. The phenotype is highly variable (summary by Freischmidt et al., 2015). For a discussion of genetic heterogeneity of FTDALS, see FTDALS1 (105550).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/902979">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_897127"><div><strong>Frontotemporal dementia and/or amyotrophic lateral sclerosis 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>897127</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4225326</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Frontotemporal dementia and/or amyotrophic lateral sclerosis-3 is an autosomal dominant neurodegenerative disorder characterized by adult or late adult onset of cognitive impairment, behavioral abnormalities, and speech apraxia and/or upper and lower motor neuron signs. Some patients may also develop Paget disease of bone. The phenotype is highly variable, even within families (summary by Rea et al., 2014). For a discussion of genetic heterogeneity of FTDALS, see FTDALS1 (105550).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/897127">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_924255"><div><strong>Alzheimer disease 9</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>924255</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4282179</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/924255">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1648386"><div><strong>Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648386</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4721893</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) is characterized by fractures (resulting from radiologically demonstrable polycystic osseous lesions), frontal lobe syndrome, and progressive presenile dementia beginning in the fourth decade. The clinical course of PLOSL can be divided into four stages: 1.. The latent stage is characterized by normal early development. 2.. The osseous stage (3rd decade of life) is characterized by pain and tenderness, mostly in ankles and feet, usually following strain or injury. Fractures are typically diagnosed several years later, most commonly in the bones of the extremities. 3.. In the early neurologic stage (4th decade of life), a change of personality begins to develop insidiously. Affected individuals show a frontal lobe syndrome (loss of judgment, euphoria, loss of social inhibitions, disturbance of concentration, and lack of insight, libido, and motor persistence) leading to serious social issues. 4.. The late neurologic stage is characterized by progressive dementia and loss of mobility. Death usually occurs before age 50 years.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1648386">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1648374"><div><strong>Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648374</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4748657</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy-2 (PLOSL2), or Nasu-Hakola disease, is a recessively inherited presenile frontal dementia with leukoencephalopathy and basal ganglia calcification. In most cases the disorder first manifests in early adulthood as pain and swelling in ankles and feet, followed by bone fractures. Neurologic symptoms manifest in the fourth decade of life as a frontal lobe syndrome with loss of judgment, euphoria, and disinhibition. Progressive decline in other cognitive domains begins to develop at about the same time. The disorder culminates in a profound dementia and death by age 50 years (summary by Klunemann et al., 2005). For a discussion of genetic heterogeneity of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy, see 221770.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1648374">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1845571"><div><strong>Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1845571</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882680</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Parkinson disease-25 (PARK25) is a progressive neurodegenerative disorder characterized by onset of parkinsonism in late childhood/adolescence and developmental delay/impaired intellectual development. Cognitive impairment is mild to moderate and nonprogressive (Fevga et al., 2023). For a general phenotypic description and a discussion of genetic heterogeneity of Parkinson disease, see 168600.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1845571">Condition Record</a></div></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_924255" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Alzheimer disease 9</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_383137" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Amyotrophic lateral sclerosis type 10</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_98277" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Chorea-acanthocytosis</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_333403" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Fragile X-associated tremor/ataxia syndrome</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_83266" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Frontotemporal dementia</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (16)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_897127" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Frontotemporal dementia and/or amyotrophic lateral sclerosis 3</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_902979" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Frontotemporal dementia and/or amyotrophic lateral sclerosis 4</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_318833" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Frontotemporal dementia and/or amyotrophic lateral sclerosis 7</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_375285" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">GRN-related frontotemporal lobar degeneration with Tdp43 inclusions</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_401097" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary spastic paraplegia 4</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_381211" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neuroferritinopathy</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1845571" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_357007" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Perry syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_116020" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pick disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648386" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648374" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38529667">Assessment and treatment of compulsive sexual behavior disorder: a sexual medicine perspective.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Briken P,
|
||
Bőthe B,
|
||
Carvalho J,
|
||
Coleman E,
|
||
Giraldi A,
|
||
Kraus SW,
|
||
Lew-Starowicz M,
|
||
Pfaus JG</span><br />
|
||
<span class="medgenPMjournal">Sex Med Rev</span>
|
||
2024 Jun 26;12(3):355-370.
|
||
doi: 10.1093/sxmrev/qeae014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38529667" target="_blank">38529667</a><a href="/pmc/articles/PMC11214846" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28925637">Hair Loss: Common Causes and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Phillips TG,
|
||
Slomiany WP,
|
||
Allison R</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2017 Sep 15;96(6):371-378.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28925637" target="_blank">28925637</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24176427">Clinical neurogenetics: behavioral management of inherited neurodegenerative disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wexler E</span><br />
|
||
<span class="medgenPMjournal">Neurol Clin</span>
|
||
2013 Nov;31(4):1121-44.
|
||
doi: 10.1016/j.ncl.2013.04.016.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24176427" target="_blank">24176427</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22impulse%20control%20disorder%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (25)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38952083">DRD4 gene polymorphism and impulse control disorder induced by dopamine agonists in Parkinson's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Torres V,
|
||
Pérez-Montesino J,
|
||
Fernández-Santiago R,
|
||
Fernández M,
|
||
Camara A,
|
||
Compta Y,
|
||
Martí MJ,
|
||
Guerra Beltran À,
|
||
Rios J,
|
||
Valldeoriola F,
|
||
Ezquerra M</span><br />
|
||
<span class="medgenPMjournal">Ann Clin Transl Neurol</span>
|
||
2024 Aug;11(8):2222-2229.
|
||
Epub 2024 Jul 1
|
||
doi: 10.1002/acn3.52111.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38952083" target="_blank">38952083</a><a href="/pmc/articles/PMC11330210" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36083776">Treatments and interventions for compulsive sexual behavior disorder with a focus on problematic pornography use: A preregistered systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Antons S,
|
||
Engel J,
|
||
Briken P,
|
||
Krüger THC,
|
||
Brand M,
|
||
Stark R</span><br />
|
||
<span class="medgenPMjournal">J Behav Addict</span>
|
||
2022 Sep 26;11(3):643-666.
|
||
Epub 2022 Sep 9
|
||
doi: 10.1556/2006.2022.00061.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36083776" target="_blank">36083776</a><a href="/pmc/articles/PMC9872540" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30792114">Prevalence of mental disorders in China: a cross-sectional epidemiological study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang Y,
|
||
Wang Y,
|
||
Wang H,
|
||
Liu Z,
|
||
Yu X,
|
||
Yan J,
|
||
Yu Y,
|
||
Kou C,
|
||
Xu X,
|
||
Lu J,
|
||
Wang Z,
|
||
He S,
|
||
Xu Y,
|
||
He Y,
|
||
Li T,
|
||
Guo W,
|
||
Tian H,
|
||
Xu G,
|
||
Xu X,
|
||
Ma Y,
|
||
Wang L,
|
||
Wang L,
|
||
Yan Y,
|
||
Wang B,
|
||
Xiao S,
|
||
Zhou L,
|
||
Li L,
|
||
Tan L,
|
||
Zhang T,
|
||
Ma C,
|
||
Li Q,
|
||
Ding H,
|
||
Geng H,
|
||
Jia F,
|
||
Shi J,
|
||
Wang S,
|
||
Zhang N,
|
||
Du X,
|
||
Du X,
|
||
Wu Y</span><br />
|
||
<span class="medgenPMjournal">Lancet Psychiatry</span>
|
||
2019 Mar;6(3):211-224.
|
||
Epub 2019 Feb 18
|
||
doi: 10.1016/S2215-0366(18)30511-X.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30792114" target="_blank">30792114</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30450025">Psychiatric Manifestation in Patients with Parkinson's Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Han JW,
|
||
Ahn YD,
|
||
Kim WS,
|
||
Shin CM,
|
||
Jeong SJ,
|
||
Song YS,
|
||
Bae YJ,
|
||
Kim JM</span><br />
|
||
<span class="medgenPMjournal">J Korean Med Sci</span>
|
||
2018 Nov 19;33(47):e300.
|
||
Epub 2018 Nov 1
|
||
doi: 10.3346/jkms.2018.33.e300.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30450025" target="_blank">30450025</a><a href="/pmc/articles/PMC6236081" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28104232">Dopamine agonist withdrawal syndrome: A comprehensive review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yu XX,
|
||
Fernandez HH</span><br />
|
||
<span class="medgenPMjournal">J Neurol Sci</span>
|
||
2017 Mar 15;374:53-55.
|
||
Epub 2017 Jan 2
|
||
doi: 10.1016/j.jns.2016.12.070.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28104232" target="_blank">28104232</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impulse%20control%20disorder%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (231)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38529667">Assessment and treatment of compulsive sexual behavior disorder: a sexual medicine perspective.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Briken P,
|
||
Bőthe B,
|
||
Carvalho J,
|
||
Coleman E,
|
||
Giraldi A,
|
||
Kraus SW,
|
||
Lew-Starowicz M,
|
||
Pfaus JG</span><br />
|
||
<span class="medgenPMjournal">Sex Med Rev</span>
|
||
2024 Jun 26;12(3):355-370.
|
||
doi: 10.1093/sxmrev/qeae014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38529667" target="_blank">38529667</a><a href="/pmc/articles/PMC11214846" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34687915">Prolactinomas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wildemberg LE,
|
||
Fialho C,
|
||
Gadelha MR</span><br />
|
||
<span class="medgenPMjournal">Presse Med</span>
|
||
2021 Dec;50(4):104080.
|
||
Epub 2021 Oct 21
|
||
doi: 10.1016/j.lpm.2021.104080.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34687915" target="_blank">34687915</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30792114">Prevalence of mental disorders in China: a cross-sectional epidemiological study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang Y,
|
||
Wang Y,
|
||
Wang H,
|
||
Liu Z,
|
||
Yu X,
|
||
Yan J,
|
||
Yu Y,
|
||
Kou C,
|
||
Xu X,
|
||
Lu J,
|
||
Wang Z,
|
||
He S,
|
||
Xu Y,
|
||
He Y,
|
||
Li T,
|
||
Guo W,
|
||
Tian H,
|
||
Xu G,
|
||
Xu X,
|
||
Ma Y,
|
||
Wang L,
|
||
Wang L,
|
||
Yan Y,
|
||
Wang B,
|
||
Xiao S,
|
||
Zhou L,
|
||
Li L,
|
||
Tan L,
|
||
Zhang T,
|
||
Ma C,
|
||
Li Q,
|
||
Ding H,
|
||
Geng H,
|
||
Jia F,
|
||
Shi J,
|
||
Wang S,
|
||
Zhang N,
|
||
Du X,
|
||
Du X,
|
||
Wu Y</span><br />
|
||
<span class="medgenPMjournal">Lancet Psychiatry</span>
|
||
2019 Mar;6(3):211-224.
|
||
Epub 2019 Feb 18
|
||
doi: 10.1016/S2215-0366(18)30511-X.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30792114" target="_blank">30792114</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30450025">Psychiatric Manifestation in Patients with Parkinson's Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Han JW,
|
||
Ahn YD,
|
||
Kim WS,
|
||
Shin CM,
|
||
Jeong SJ,
|
||
Song YS,
|
||
Bae YJ,
|
||
Kim JM</span><br />
|
||
<span class="medgenPMjournal">J Korean Med Sci</span>
|
||
2018 Nov 19;33(47):e300.
|
||
Epub 2018 Nov 1
|
||
doi: 10.3346/jkms.2018.33.e300.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30450025" target="_blank">30450025</a><a href="/pmc/articles/PMC6236081" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28925637">Hair Loss: Common Causes and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Phillips TG,
|
||
Slomiany WP,
|
||
Allison R</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2017 Sep 15;96(6):371-378.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28925637" target="_blank">28925637</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impulse%20control%20disorder%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (223)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38952083">DRD4 gene polymorphism and impulse control disorder induced by dopamine agonists in Parkinson's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Torres V,
|
||
Pérez-Montesino J,
|
||
Fernández-Santiago R,
|
||
Fernández M,
|
||
Camara A,
|
||
Compta Y,
|
||
Martí MJ,
|
||
Guerra Beltran À,
|
||
Rios J,
|
||
Valldeoriola F,
|
||
Ezquerra M</span><br />
|
||
<span class="medgenPMjournal">Ann Clin Transl Neurol</span>
|
||
2024 Aug;11(8):2222-2229.
|
||
Epub 2024 Jul 1
|
||
doi: 10.1002/acn3.52111.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38952083" target="_blank">38952083</a><a href="/pmc/articles/PMC11330210" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36083776">Treatments and interventions for compulsive sexual behavior disorder with a focus on problematic pornography use: A preregistered systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Antons S,
|
||
Engel J,
|
||
Briken P,
|
||
Krüger THC,
|
||
Brand M,
|
||
Stark R</span><br />
|
||
<span class="medgenPMjournal">J Behav Addict</span>
|
||
2022 Sep 26;11(3):643-666.
|
||
Epub 2022 Sep 9
|
||
doi: 10.1556/2006.2022.00061.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36083776" target="_blank">36083776</a><a href="/pmc/articles/PMC9872540" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34687915">Prolactinomas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wildemberg LE,
|
||
Fialho C,
|
||
Gadelha MR</span><br />
|
||
<span class="medgenPMjournal">Presse Med</span>
|
||
2021 Dec;50(4):104080.
|
||
Epub 2021 Oct 21
|
||
doi: 10.1016/j.lpm.2021.104080.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34687915" target="_blank">34687915</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30450025">Psychiatric Manifestation in Patients with Parkinson's Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Han JW,
|
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Ahn YD,
|
||
Kim WS,
|
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Shin CM,
|
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Jeong SJ,
|
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Song YS,
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2018 Nov 19;33(47):e300.
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<div class="nl"><a target="_blank" href="/pubmed/28104232">Dopamine agonist withdrawal syndrome: A comprehensive review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Yu XX,
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Fernandez HH</span><br />
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2017 Mar 15;374:53-55.
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Epub 2017 Jan 2
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<span class="bold">PMID: </span><a href="/pubmed/28104232" target="_blank">28104232</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impulse%20control%20disorder%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (173)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/36930990">Predicting impulse control disorder in Parkinson's Disease: Is there a formula?</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Valldeoriola F,
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Torres V</span><br />
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<span class="medgenPMjournal">Eur Neuropsychopharmacol</span>
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2023 Jul;72:4-5.
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Epub 2023 Mar 15
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doi: 10.1016/j.euroneuro.2023.02.017.
|
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<span class="bold">PMID: </span><a href="/pubmed/36930990" target="_blank">36930990</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28802938">Impulse Control and Related Disorders in Parkinson's Disease.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Weintraub D,
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Claassen DO</span><br />
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<span class="medgenPMjournal">Int Rev Neurobiol</span>
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2017;133:679-717.
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Epub 2017 Jun 1
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<span class="bold">PMID: </span><a href="/pubmed/28802938" target="_blank">28802938</a></div>
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||
<div class="nl"><a target="_blank" href="/pubmed/27198992">Tracking online poker problem gamblers with player account-based gambling data only.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Luquiens A,
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Tanguy ML,
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Benyamina A,
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Lagadec M,
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2016 Dec;25(4):333-342.
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|
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<div class="nl"><a target="_blank" href="/pubmed/21724302">Dopaminergic agonists in Parkinson's disease.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Alonso Cánovas A,
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Luquin Piudo R,
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García Ruiz-Espiga P,
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Burguera JA,
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Campos Arillo V,
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Castro A,
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Linazasoro G,
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López Del Val J,
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<span class="medgenPMjournal">Neurologia</span>
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2014 May;29(4):230-41.
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<span class="bold">PMID: </span><a href="/pubmed/21724302" target="_blank">21724302</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/3573048">The mislabeling of sexual impulsivity.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Barth RJ,
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Kinder BN</span><br />
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<span class="medgenPMjournal">J Sex Marital Ther</span>
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<span class="bold">PMID: </span><a href="/pubmed/3573048" target="_blank">3573048</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impulse%20control%20disorder%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (76)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36930990">Predicting impulse control disorder in Parkinson's Disease: Is there a formula?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Valldeoriola F,
|
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Torres V</span><br />
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<span class="medgenPMjournal">Eur Neuropsychopharmacol</span>
|
||
2023 Jul;72:4-5.
|
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Epub 2023 Mar 15
|
||
doi: 10.1016/j.euroneuro.2023.02.017.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36930990" target="_blank">36930990</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34324797">Side Effect Profiles of Selective Serotonin Reuptake Inhibitors: A Cross-Sectional Study in a Naturalistic Setting.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Anagha K,
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Shihabudheen P,
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Uvais NA</span><br />
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<span class="medgenPMjournal">Prim Care Companion CNS Disord</span>
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2021 Jul 29;23(4)
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doi: 10.4088/PCC.20m02747.
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<span class="bold">PMID: </span><a href="/pubmed/34324797" target="_blank">34324797</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28229895">Impulse control disorders and levodopa-induced dyskinesias in Parkinson's disease: an update.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Voon V,
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Napier TC,
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Frank MJ,
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Sgambato-Faure V,
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Grace AA,
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Rodriguez-Oroz M,
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Obeso J,
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Bezard E,
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Fernagut PO</span><br />
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<span class="medgenPMjournal">Lancet Neurol</span>
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2017 Mar;16(3):238-250.
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Epub 2017 Feb 15
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doi: 10.1016/S1474-4422(17)30004-2.
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<span class="bold">PMID: </span><a href="/pubmed/28229895" target="_blank">28229895</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/27198992">Tracking online poker problem gamblers with player account-based gambling data only.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Luquiens A,
|
||
Tanguy ML,
|
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Benyamina A,
|
||
Lagadec M,
|
||
Aubin HJ,
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||
Reynaud M</span><br />
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<span class="medgenPMjournal">Int J Methods Psychiatr Res</span>
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2016 Dec;25(4):333-342.
|
||
Epub 2016 May 19
|
||
doi: 10.1002/mpr.1510.
|
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<span class="bold">PMID: </span><a href="/pubmed/27198992" target="_blank">27198992</a><a href="/pmc/articles/PMC6860303" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26577509">The Subthalamic Nucleus, Limbic Function, and Impulse Control.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Rossi PJ,
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Gunduz A,
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Okun MS</span><br />
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<span class="medgenPMjournal">Neuropsychol Rev</span>
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2015 Dec;25(4):398-410.
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Epub 2015 Nov 14
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doi: 10.1007/s11065-015-9306-9.
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<span class="bold">PMID: </span><a href="/pubmed/26577509" target="_blank">26577509</a><a href="/pmc/articles/PMC4792181" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impulse%20control%20disorder%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (138)</a></div></div>
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|
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|
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<div class="portlet mgSection" id="ID_104">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
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<div class="nl"><a target="_blank" href="/pubmed/39138440">Comorbidity of binge eating disorder and other psychiatric disorders: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kowalewska E,
|
||
Bzowska M,
|
||
Engel J,
|
||
Lew-Starowicz M</span><br />
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||
<span class="medgenPMjournal">BMC Psychiatry</span>
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||
2024 Aug 13;24(1):556.
|
||
doi: 10.1186/s12888-024-05943-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39138440" target="_blank">39138440</a><a href="/pmc/articles/PMC11323383" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37985276">Impulse Control Disorders in Patients with Pituitary Tumors Treated with Dopamine Agonists: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hamblin R,
|
||
Karavitaki N</span><br />
|
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<span class="medgenPMjournal">Arch Med Res</span>
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||
2023 Dec;54(8):102910.
|
||
Epub 2023 Nov 19
|
||
doi: 10.1016/j.arcmed.2023.102910.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37985276" target="_blank">37985276</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36087861">Delay discounting in Parkinson's disease: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pennisi P,
|
||
Salehinejad MA,
|
||
Corso AM,
|
||
Merlo EM,
|
||
Avenanti A,
|
||
Vicario CM</span><br />
|
||
<span class="medgenPMjournal">Behav Brain Res</span>
|
||
2023 Jan 5;436:114101.
|
||
Epub 2022 Sep 7
|
||
doi: 10.1016/j.bbr.2022.114101.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36087861" target="_blank">36087861</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36083776">Treatments and interventions for compulsive sexual behavior disorder with a focus on problematic pornography use: A preregistered systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Antons S,
|
||
Engel J,
|
||
Briken P,
|
||
Krüger THC,
|
||
Brand M,
|
||
Stark R</span><br />
|
||
<span class="medgenPMjournal">J Behav Addict</span>
|
||
2022 Sep 26;11(3):643-666.
|
||
Epub 2022 Sep 9
|
||
doi: 10.1556/2006.2022.00061.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36083776" target="_blank">36083776</a><a href="/pmc/articles/PMC9872540" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34281267">A Systematic Review of Parkinson's Disease Pharmacogenomics: Is There Time for Translation into the Clinics?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vuletić V,
|
||
Rački V,
|
||
Papić E,
|
||
Peterlin B</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2021 Jul 5;22(13)
|
||
doi: 10.3390/ijms22137213.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34281267" target="_blank">34281267</a><a href="/pmc/articles/PMC8268929" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impulse%20control%20disorder%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (10)</a></div></div>
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